Journal articles on the topic 'RUNT domain family'
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Thirunavukkarasu, Kannan, Muktar Mahajan, Keith W. McLarren, Stefano Stifani, and Gerard Karsenty. "Two Domains Unique to Osteoblast-Specific Transcription Factor Osf2/Cbfa1 Contribute to Its Transactivation Function and Its Inability To Heterodimerize with Cbfβ." Molecular and Cellular Biology 18, no. 7 (July 1, 1998): 4197–208. http://dx.doi.org/10.1128/mcb.18.7.4197.
Full textAronson, B. D., A. L. Fisher, K. Blechman, M. Caudy, and J. P. Gergen. "Groucho-dependent and -independent repression activities of Runt domain proteins." Molecular and Cellular Biology 17, no. 9 (September 1997): 5581–87. http://dx.doi.org/10.1128/mcb.17.9.5581.
Full textGolling, G., L. Li, M. Pepling, M. Stebbins, and J. P. Gergen. "Drosophila homologs of the proto-oncogene product PEBP2/CBF beta regulate the DNA-binding properties of Runt." Molecular and Cellular Biology 16, no. 3 (March 1996): 932–42. http://dx.doi.org/10.1128/mcb.16.3.932.
Full textKagoshima, Hiroshi, Katsuya Shigesada, Masanobu Satake, Yoshiaki Ito, Hiroyuki Miyoshi, Misao Ohki, Melissa Pepling, and Peter Gergen. "The runt domain identifies a new family of heterometric transcriptional regulators." Trends in Genetics 9, no. 10 (October 1993): 338–41. http://dx.doi.org/10.1016/0168-9525(93)90026-e.
Full textLi, L. H., and J. P. Gergen. "Differential interactions between Brother proteins and Runt domain proteins in the Drosophila embryo and eye." Development 126, no. 15 (August 1, 1999): 3313–22. http://dx.doi.org/10.1242/dev.126.15.3313.
Full textScarpa, Frank J., Madhuri Paul, Rachel Daringer, Sally Agersborg, Vincent A. Funari, and Forrest J. Blocker. "Abstract 2281: Molecular profiling of the RUNX1 RUNT domain in myeloid disorders." Cancer Research 82, no. 12_Supplement (June 15, 2022): 2281. http://dx.doi.org/10.1158/1538-7445.am2022-2281.
Full textKaminker, Joshua S., Rajan Singh, Tim Lebestky, Huajun Yan, and Utpal Banerjee. "Redundant function of Runt Domain binding partners, Big brother and Brother, during Drosophila development." Development 128, no. 14 (July 15, 2001): 2639–48. http://dx.doi.org/10.1242/dev.128.14.2639.
Full textFukushima-Nakase, Yoko, Yoshinori Naoe, Ichiro Taniuchi, Hajime Hosoi, Tohru Sugimoto, and Tsukasa Okuda. "Shared and distinct roles mediated through C-terminal subdomains of acute myeloid leukemia/Runt-related transcription factor molecules in murine development." Blood 105, no. 11 (June 1, 2005): 4298–307. http://dx.doi.org/10.1182/blood-2004-08-3372.
Full textMahadeveraju, Sharvani, Young-Ho Jung, and James W. Erickson. "Evidence That Runt Acts as a Counter-Repressor of Groucho During Drosophila melanogaster Primary Sex Determination." G3: Genes|Genomes|Genetics 10, no. 7 (May 26, 2020): 2487–96. http://dx.doi.org/10.1534/g3.120.401384.
Full textCheney, Matthew D., Yizhou Liu, Yunpeng Zhou, Maksymilian Chruszcz, Thomas M. Laue, Wladek Minor, John H. Bushweller, and Nancy A. Speck. "Structural and Functional Characterization of the NHR2 and Runt Domains of AML1/ETO." Blood 104, no. 11 (November 16, 2004): 482. http://dx.doi.org/10.1182/blood.v104.11.482.482.
Full textOsato, Motomi, Norio Asou, Essam Abdalla, Koyu Hoshino, Hiroshi Yamasaki, Toshiya Okubo, Hitoshi Suzushima, et al. "Biallelic and Heterozygous Point Mutations in the Runt Domain of theAML1/PEBP2B Gene Associated With Myeloblastic Leukemias." Blood 93, no. 6 (March 15, 1999): 1817–24. http://dx.doi.org/10.1182/blood.v93.6.1817.406k36_1817_1824.
Full textAhn, Mee-Young, Suk-Chul Bae, Mitsuo Maruyama, and Yoshiaki Ito. "Comparison of the human genomic structure of the Runt domain-encoding PEBP2/CBFα gene family." Gene 168, no. 2 (January 1996): 279–80. http://dx.doi.org/10.1016/0378-1119(95)00751-2.
Full textWalrad, Pegine B., Saiyu Hang, Genevieve S. Joseph, Julia Salas, and J. Peter Gergen. "Distinct Contributions of Conserved Modules to Runt Transcription Factor Activity." Molecular Biology of the Cell 21, no. 13 (July 2010): 2315–26. http://dx.doi.org/10.1091/mbc.e09-11-0953.
Full textCheney, Matthew D., Yizhou Liu, Justin J. Gaudet, Maksymilian Chruszcz, Stephen M. Lukasik, Daisuke Sugiyama, Jeff Lary, et al. "Structural and Functional Characterization of the NHR2 and Runt Domains of AML1/ETO." Blood 106, no. 11 (November 16, 2005): 2854. http://dx.doi.org/10.1182/blood.v106.11.2854.2854.
Full textSugiyama, Daisuke, Hiroko Sugiyama, and Nancy A. Speck. "A Role for Twist in Thymocyte Development." Blood 106, no. 11 (November 16, 2005): 4252. http://dx.doi.org/10.1182/blood.v106.11.4252.4252.
Full textGu, Ting-Lei, Tamara L. Goetz, Barbara J. Graves, and Nancy A. Speck. "Auto-Inhibition and Partner Proteins, Core-Binding Factor β (CBFβ) and Ets-1, Modulate DNA Binding by CBFα2 (AML1)." Molecular and Cellular Biology 20, no. 1 (January 1, 2000): 91–103. http://dx.doi.org/10.1128/mcb.20.1.91-103.2000.
Full textNielsen, Alek d., Sayer Alharbi, Cassandra M. Hirsch, Bartlomiej P. Przychodzen, Mikkael A. Sekeres, Yogen Saunthararajah, Hetty E. Carraway, and Jaroslaw P. Maciejewski. "Germline Variants of RUNX-1 in Myeloid Malignancy." Blood 128, no. 22 (December 2, 2016): 3926. http://dx.doi.org/10.1182/blood.v128.22.3926.3926.
Full textLevanon, D., V. Negreanu, Y. Bernstein, I. Bar-Am, L. Avivi, and Y. Groner. "AML1, AML2, and AML3, the Human Members of the runt domain Gene-Family: cDNA Structure, Expression, and Chromosomal Localization." Genomics 23, no. 2 (September 1994): 425–32. http://dx.doi.org/10.1006/geno.1994.1519.
Full textBuijs, Arjan, Pino Poddighe, Richard van Wijk, Wouter van Solinge, Eric Borst, Leo Verdonck, Anton Hagenbeek, Peter Pearson, and Henk Lokhorst. "A novel CBFA2 single-nucleotide mutation in familial platelet disorder with propensity to develop myeloid malignancies." Blood 98, no. 9 (November 1, 2001): 2856–58. http://dx.doi.org/10.1182/blood.v98.9.2856.
Full textSong, Xiaorui, Ying Song, Miren Dong, Zhaoqun Liu, Weilin Wang, Lingling Wang, and Linsheng Song. "A new member of the runt domain family from Pacific oyster Crassostrea gigas (CgRunx) potentially involved in immune response and larvae hematopoiesis." Fish & Shellfish Immunology 89 (June 2019): 228–36. http://dx.doi.org/10.1016/j.fsi.2019.03.066.
Full textWang, Kainan, Cindy Degerny, Minghong Xu, and Xiang-Jiao Yang. "YAP, TAZ, and Yorkie: a conserved family of signal-responsive transcriptional coregulators in animal development and human diseaseThis paper is one of a selection of papers published in this Special Issue, entitled CSBMCB’s 51st Annual Meeting – Epigenetics and Chromatin Dynamics, and has undergone the Journal’s usual peer review process." Biochemistry and Cell Biology 87, no. 1 (February 2009): 77–91. http://dx.doi.org/10.1139/o08-114.
Full textBerardi, Marcelo J., Chaohong Sun, Michael Zehr, Frits Abildgaard, Jeff Peng, Nancy A. Speck, and John H. Bushweller. "The Ig fold of the core binding factor α Runt domain is a member of a family of structurally and functionally related Ig-fold DNA-binding domains." Structure 7, no. 10 (October 1999): 1247–56. http://dx.doi.org/10.1016/s0969-2126(00)80058-1.
Full textBruno, Ludovica, Luca Mazzarella, Maarten Hoogenkamp, Arnulf Hertweck, Bradley S. Cobb, Stephan Sauer, Suzana Hadjur, et al. "Runx proteins regulate Foxp3 expression." Journal of Experimental Medicine 206, no. 11 (October 19, 2009): 2329–37. http://dx.doi.org/10.1084/jem.20090226.
Full textZhang, Xiuli, Yining Li, Pingzhen Yang, Xiaoyu Liu, Lihe Lu, Yanting Chen, Xinglong Zhong, et al. "Trimethylamine-N-Oxide Promotes Vascular Calcification Through Activation of NLRP3 (Nucleotide-Binding Domain, Leucine-Rich-Containing Family, Pyrin Domain-Containing-3) Inflammasome and NF-κB (Nuclear Factor κB) Signals." Arteriosclerosis, Thrombosis, and Vascular Biology 40, no. 3 (March 2020): 751–65. http://dx.doi.org/10.1161/atvbaha.119.313414.
Full textSpender, Lindsay C., Georgina H. Cornish, Alexandra Sullivan, and Paul J. Farrell. "Expression of Transcription Factor AML-2 (RUNX3, CBFα-3) Is Induced by Epstein-Barr Virus EBNA-2 and Correlates with the B-Cell Activation Phenotype." Journal of Virology 76, no. 10 (May 15, 2002): 4919–27. http://dx.doi.org/10.1128/jvi.76.10.4919-4927.2002.
Full textAkamatsu, Yoshiko, Shin-ichi Tsukumo, Hiroshi Kagoshima, Naoya Tsurushita, and Katsuya Shigesada. "A simple screening for mutant DNA binding proteins: application to murine transcription factor PEBP2α subunit, a founding member of the Runt domain protein family." Gene 185, no. 1 (January 1997): 111–17. http://dx.doi.org/10.1016/s0378-1119(96)00644-0.
Full textMasuda, Tatsuya, Hirohito Kubota, Naoya Sakuramoto, Asuka Hada, Ayaka Horiuchi, Asami Sasaki, Kanako Takeda, et al. "RUNX-NFAT Axis As a Novel Therapeutic Target for AML and T Cell Immunity." Blood 136, Supplement 1 (November 5, 2020): 25–26. http://dx.doi.org/10.1182/blood-2020-143458.
Full textYamaguchi, Akira, Toshihisa Komori, and Tatsuo Suda. "Regulation of Osteoblast Differentiation Mediated by Bone Morphogenetic Proteins, Hedgehogs, and Cbfa1." Endocrine Reviews 21, no. 4 (August 1, 2000): 393–411. http://dx.doi.org/10.1210/edrv.21.4.0403.
Full textAlkadi, Halah, David McKellar, Tao Zhen, Tatiana Karpova, Lisa J. Garrett, Yongxing Gao, Anfal A. Alsadhan, et al. "The VWRPY Domain Is Essential for RUNX1 Function in Hematopoietic Progenitor Cell Maturation and Megakaryocyte Differentiation." Blood 132, Supplement 1 (November 29, 2018): 1319. http://dx.doi.org/10.1182/blood-2018-99-113400.
Full textMerriman, Harold L., Andre J. van Wijnen, Scott Hiebert, Joseph P. Bidwell, Edward Fey, Jane Lian, Janet Stein, and Gary S. Stein. "The Tissue-Specific Nuclear Matrix Protein, NMP-2, Is a Member of the AML/PEBP2/Runt Domain Transcription Factor Family: Interactions with the Osteocalcin Gene Promoter." Biochemistry 34, no. 40 (October 1995): 13125–32. http://dx.doi.org/10.1021/bi00040a025.
Full textCoffman, James A., Carmen V. Kirchhamer, Michael G. Harrington, and Eric H. Davidson. "SpRunt-1, a New Member of the Runt Domain Family of Transcription Factors, Is a Positive Regulator of the Aboral Ectoderm-SpecificCyIIIAGene in Sea Urchin Embryos." Developmental Biology 174, no. 1 (February 1996): 43–54. http://dx.doi.org/10.1006/dbio.1996.0050.
Full textHuang, Hui, Zachary Waldon, Gordon Chan, Helen Zhu, Hanno Steen, Gen-Sheng Feng, Benjamin Neel, and Alan Cantor. "Tyrosine Phosphorylation of Runx1 In Megakaryocytes by Src Family Kinases." Blood 116, no. 21 (November 19, 2010): 742. http://dx.doi.org/10.1182/blood.v116.21.742.742.
Full textHazourli, Sawcene, Pierre Chagnon, Raouf Fetni, Lambert Busque, and Josee Hebert. "Overexpression of MEL1 as a Novel Fusion Partner of AML1 in the Blastic Phase of Chronic Myeloid Leukemia with the Recurrent Cryptic Translocation t(1;21)(p36.3;q22)." Blood 106, no. 11 (November 16, 2005): 4332. http://dx.doi.org/10.1182/blood.v106.11.4332.4332.
Full textKanto, Satoru, Marcin Grynberg, Yoshiyuki Kaneko, Jun Fujita, and Masanobu Satake. "A variant of Runx2 that differs from the bone isoform in its splicing is expressed in spermatogenic cells." PeerJ 4 (April 4, 2016): e1862. http://dx.doi.org/10.7717/peerj.1862.
Full textParedes, Roberto, Gloria Arriagada, Fernando Cruzat, Alejandro Villagra, Juan Olate, Kaleem Zaidi, Andre van Wijnen, et al. "Bone-Specific Transcription Factor Runx2 Interacts with the 1α,25-Dihydroxyvitamin D3 Receptor To Up-Regulate Rat Osteocalcin Gene Expression in Osteoblastic Cells." Molecular and Cellular Biology 24, no. 20 (October 15, 2004): 8847–61. http://dx.doi.org/10.1128/mcb.24.20.8847-8861.2004.
Full textSkokowa, Julia, Doris Steinemann, Jenny Katsman-Kuipers, Cornelia Zeidler, Olga Klimenkova, Maksim Klimiankou, Murat Uenalan, et al. "Cooperativity Of RUNX1 and CSF3R Mutations In The Development Of Leukemia In Severe Congenital Neutropenia: A Unique Pathway In Myeloid Leukemogenesis." Blood 122, no. 21 (November 15, 2013): 444. http://dx.doi.org/10.1182/blood.v122.21.444.444.
Full textChurpek, Jane E., Jacqueline S. Garcia, Jozef Madzo, Sarah Jackson, Kenan Onel, and Lucy A. Godley. "Molecular Characterization of a Novel 3' Mutation in RUNX1 in a New Pedigree with Familial Platelet Disorder." Blood 114, no. 22 (November 20, 2009): 1626. http://dx.doi.org/10.1182/blood.v114.22.1626.1626.
Full textTakazawa, Y., K. Tsuji, A. Nifuji, H. Kurosawa, Y. Ito, and M. Noda. "An osteogenesis-related transcription factor, core-binding factor A1, is constitutively expressed in the chondrocytic cell line TC6, and its expression is upregulated by bone morphogenetic protein-2." Journal of Endocrinology 165, no. 3 (June 1, 2000): 579–86. http://dx.doi.org/10.1677/joe.0.1650579.
Full textMao, Shifeng, Richard C. Frank, Jin Zhang, Yasushi Miyazaki, and Stephen D. Nimer. "Functional and Physical Interactions between AML1 Proteins and an ETS Protein, MEF: Implications for the Pathogenesis of t(8;21)-Positive Leukemias." Molecular and Cellular Biology 19, no. 5 (May 1, 1999): 3635–44. http://dx.doi.org/10.1128/mcb.19.5.3635.
Full textGarcia, Jacqueline S., Jozef Madzo, Devin Cooper, Sarah A. Jackson, Kenan Onel, Richard A. Larson, Andrew Artz, and Lucy A. Godley. "Pre-Donor Evaluation of an HLA Matched Sibling Identifies a Novel Inherited RUNX1 Mutation Encoding a Missense Mutation Found Outside of the RUNT Domain in Familial Platelet Disorder." Blood 116, no. 21 (November 19, 2010): 2709. http://dx.doi.org/10.1182/blood.v116.21.2709.2709.
Full textGrossmann, Vera, Alexander Kohlmann, Hans-Ulrich Klein, Sonja Schindela, Susanne Schnittger, Martin Dugas, Wolfgang Kern, Torsten Haferlach, and Claudia Haferlach. "Targeted Next-Generation Sequencing and Genome-Wide High-Resolution Copy Number DNA Arrays Allow the Identification of Five Novel RUNX1 Fusions In Hematological Malignancies." Blood 116, no. 21 (November 19, 2010): 1193. http://dx.doi.org/10.1182/blood.v116.21.1193.1193.
Full textKirito, Keita, Toru Mitsumori, Takahiro Nagashima, Masae Kunitama, Kei Nakajima, Kozue Yoshida, Yongzhen Hu, Mitsuhiro Yanagai, and Norio Komatsu. "A Novel Inherited Single-Nucleotide Mutation in 5′-UTR in the Transcription Factor RUNX1 in Familial Platelet Disorder with Propensity To Develop Myeloid Malignancies." Blood 108, no. 11 (November 16, 2006): 1917. http://dx.doi.org/10.1182/blood.v108.11.1917.1917.
Full textCesari, Stella, John Moore, Chunhong Chen, Daryl Webb, Sambasivam Periyannan, Rohit Mago, Maud Bernoux, Evans S. Lagudah, and Peter N. Dodds. "Cytosolic activation of cell death and stem rust resistance by cereal MLA-family CC–NLR proteins." Proceedings of the National Academy of Sciences 113, no. 36 (August 23, 2016): 10204–9. http://dx.doi.org/10.1073/pnas.1605483113.
Full textSatoh, Yusuke, Itaru Matsumura, Sachiko Ezoe, Hirokazu Tanaka, Takafumi Yokota, Jun Ishikawa, Kenji Oritani, and Yuzuru Kanakura. "The Function of AML1 (RUNX1) C-Deletion Mutant in Hematopoietic Stem/Progenitor Cells." Blood 106, no. 11 (November 16, 2005): 1738. http://dx.doi.org/10.1182/blood.v106.11.1738.1738.
Full textBrown, Anna L., Christopher N. Hahn, Catherine Carmichael, Ella Wilkins, Milena Babic, Chan-Eng Chong, Xiao-Chun Li, et al. "Expanded Phenotypic and Genetic Heterogeneity in the Clinical Spectrum of FPD-AML: Lymphoid Malignancies and Skin Disorders Are Common Features in Carriers of Germline RUNX1 Mutations." Blood 128, no. 22 (December 2, 2016): 1212. http://dx.doi.org/10.1182/blood.v128.22.1212.1212.
Full textSun, Qing, Nicholas C. Collins, Michael Ayliffe, Shavannor M. Smith, Jeff Drake, Tony Pryor, and Scot H. Hulbert. "Recombination Between Paralogues at the rp1 Rust Resistance Locus in Maize." Genetics 158, no. 1 (May 1, 2001): 423–38. http://dx.doi.org/10.1093/genetics/158.1.423.
Full textYu, Kai, Matthew Merguerian, Natalie Deuitch, Erica Bresciani, Joie Davis, Kathleen Craft, Lea C. Cunningham, and Paul P. Liu. "Genomic Landscape of RUNX1-Familial Platelet Disorder with Myeloid Malignancies Reveals Rising Clonal Hematopoiesis." Blood 138, Supplement 1 (November 5, 2021): 1090. http://dx.doi.org/10.1182/blood-2021-151781.
Full textKwan, Tsz-Ki, Chi-Keung Cheng, Suk-Hang Cheng, Natalie P. H. Chan, Rosalina Ip, Raymond S. M. Wong, Sze-Fai Yip, Chi-Kong Li, and Margaret H. L. Ng. "RUNX3 Expression Is an Independent Prognostic Factor in Cytogenetically Abnormal Adult Acute Myeloid Leukemia (AML) Patients with Wild-Type FLT3." Blood 116, no. 21 (November 19, 2010): 1662. http://dx.doi.org/10.1182/blood.v116.21.1662.1662.
Full textHowles, Paul, Greg Lawrence, Jean Finnegan, Helen McFadden, Michael Ayliffe, Peter Dodds, and Jeff Ellis. "Autoactive Alleles of the Flax L6 Rust Resistance Gene Induce Non-Race-Specific Rust Resistance Associated with the Hypersensitive Response." Molecular Plant-Microbe Interactions® 18, no. 6 (June 2005): 570–82. http://dx.doi.org/10.1094/mpmi-18-0570.
Full textKumar, Dhananjay, Anjali Kapoor, Dharmendra Singh, Lopamudra Satapathy, Ashwini Kumar Singh, Manish Kumar, Kumble Vinod Prabhu, and Kunal Mukhopadhyay. "Functional characterisation of a WRKY transcription factor of wheat and its expression analysis during leaf rust pathogenesis." Functional Plant Biology 41, no. 12 (2014): 1295. http://dx.doi.org/10.1071/fp14077.
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