Journal articles on the topic 'Rubaiyat'

In 2005, 212 ha of grapes were grown in Oklahoma and more than 30 licensed wineries were in operation. With this increase in grape growing and wine making comes the necessity to evaluate commercially appropriate cultivars. `Rubaiyat' was a cross between Seibel 5437 and `Bailey' made at Oklahoma State University by Herman Hinrichs in 1952. The overall genetic constitution of `Rubaiyat' (based on disomic inheritance) is 37.5% V. lincecumii, 31.25% V. vinifera, 18.75% V. labrusca, 6.25% V. rupestris, and 6.25% V. riparia. `Rubaiyat' is a dark blue-black grape that ripens in mid-August. The berries are medium-sized and round. The clusters are medium in size with a long shoulder. The vine has medium vigor and good to very good disease resistance. The juice is very dark red with about 19% sugars and tartaric acid levels of 0.63%. The wine is fruity and has good balance. A slight “foxy” flavor from the V. labrusca is sometimes evident in wine made from `Rubaiyat'. Currently, other hybrid grape cultivars such as `Chambourcin' are more popular for use as red wine varietals than `Rubaiyat'. However, in observation trials in Oklahoma, `Rubaiyat' compares favorably to `Chambourcin' in quality and may outyield it. Perhaps the greatest potential for `Rubaiyat' is as a teinturier, since it has the attribute of red flesh derived from its progenitor `Alicante Bouschet', a parent of `Alicante Ganzin'. `Rubaiyat' is not widely grown, but the potential exists for it to become an important cultivar for Oklahoma and surrounding states.

The present study attempted to examine Edward FitzGerald, who would translate Omar Khayyam's Rubaiyat (1859), was interested in Persian poetry. Translation deals with power and authority and most of the time the ideology of source text changes in favor of the dominant ideology of target text. Victorian people‘s scornful outlook toward East led to ideological manipulation of source texts by translators such as Fitzgerald. His strange reduction in his translations, especially in Khayyam's Rubaiyat results in the necessity of investigating his translation from ideological point of view. Surprisingly translation of Khayyam’s Rubaiyat has never been studied from ideological perspective and is unknown for many literary scholars. Victorian issues had a strong effect on FitzGerald‘s selection of some Khayyam's Rubaiyat.

This article follows two branches of Tsur's cognitive poetic theory to their logical conclusion and applies them to Fitzgerald's Rubaiyat of Omar Khayyam where they are fully validated. The first branch emphasizes the expressiveness of speech sounds (phonemes) and the second branch the importance of the Gestalt principle of closure to poetry. Rubaiyat were phonetically transcribed and their phonemes were then categorized in terms of emotional character. The closural device of a return to baseline described the preferential use of active phonemes in the rubaiyat while the closural allusion of definitive termination described the preferential use of pleasant phonemes. Clynes' concept of the essentic form for grief was used to explain the rise and fall of preferential activation in the first three lines of each quatrain. The emotional picture drawn of the rubaiyat on the basis of these procedures was one of fatalism or emotional resignation. General patterns and individual examples are discussed.

This research discusses the efforts of teachers in improving the literacy ability of the Qur’an students through the rubaiyat method at SD Inpres 6 Lolu Palu. The formulation of the problem in this research is how is the teacher's effort to improve the students' literacy in reading and writing through the rubaiyat method in SD Inpres 6 Lolu Palu? and what are the supporting factors and inhibiting factors in improving students' literacy in the Qur’an through the rubaiyat method? This type of research used in this thesis is qualitative research. Data collection techniques used were observation (interviews) and documentation. Furthermore, the data analysis used is data reduction and data presentation. In an effort to improve the literacy skills of the Qur’an (BTQ) students through the rubaiyat method in SD Inpres 6 Lolu Palu, teachers as educators give efforts to give the task of writing verses that are in the Qur’an namely, memorizing short suras, and teaching recitation. Based on the results of research conducted by the author In an effort to improve the literacy skills of students through the rubaiyat method there are several factors, namely supporting factors and inhibiting factors. As for the supporting factors in improving the students' literacy in the Qur’an, students are facilities such as books, fans, the Qur’an and iqra, as well as a comfortable classroom. While the inhibiting factor is the lack of media or teaching aids that are used during the learning process. The implication in this research is the government, all schools, especially school principals, PAI teachers, and BTQ teachers can work together in improving the students' literacy skills through the rubaiyat method in order to be able to emphasize students more about the importance of learning the Qur’an and reading it according to science Tajweed.

En su artículo «The tale of the inimitable Rubaiyat», T. Leacock- Seghatolislami replantea el debate sobre la traducción que el poeta y académico inglés Edward FitzGerald realizó del clásico persa Rubaiyat. Estudiante ocasional del persa, los conocimientos que FitzGerald tenía de esta lengua eran rudimentarios y, en su trabajo, según se documentó con posterioridad, echaba mano de una técnica de interpretación del texto basada en el uso indiscriminado del diccionario y en un sentido muy laxo de la fidelidad

Among the literati and men of culture of Iran, it is not exaggerated to call Khayyam one of the vaguest figures. One might recognize him certainly and resolutely through his philosophical and scientific works; however, it was his Rubaiyat attributed to him which created many arguments. This paper studies Hakim Omar Khayyam’s Rubaiyat in English and Persian language feature and non-biographical movies; hence, biographical movies depicting factual or imaginary life of Khayyam or any serials, TV productions, documentaries, non- English, non- Persian movies are not included. The aim is to expound any relationships between the film and Rubaiyat; therefore, according to the type of the applied quatrain, movie genre, plot, some categories are propounded to classify the movies in which Khayyam’s quatrains are quoted such as Transiency-Death, Transiency-Carpe Diem, Heaven and Hell, and Determinism. Indeed, these categories can be applied to the theme of the movies or a single scene in which the stanza is quoted.

Este trabalho visa a uma reflexão sobre o contexto editorial e intelectual da difusão da obra de Rabindranath Tagore no Brasil, no contexto do Modernismo. Enfatiza-se o trabalho editorial da José Olympio Editora nesse processo, e ainda os desdobramentos pedagógicos da presença da obra de Tagore no Brasil.

The fact that quatrains known as Rubiyat of Omar Khayyam were not really composed by the twelfth century astronomer of that name, but composed by various hands and made into collections later, is widely accepted. This paper examines under what political and social atmosphere in later times, the collections began to be compiled, and what elements of scepticism, irreligion, mysticism and even rationalism entered into them. It is argued that the collections retained their popularity and freely circulated wherever Persian was cultivated down to modern times.

Since its conception in France in 1877, Comparative Literature, always subject to a critique of Eurocentrism, has been in a state of perpetual crisis. In “The Old/New Question of Comparison in Literary Studies: A Post-European Perspective” (2004), Ray Chow argued for a Post-European perspective in which comparatists begin with the home culture and look outwards to the European cultures, contrary to the dominant approach of doing just otherwise. Missing in Chow’s argument is the position of translation in this post-European perspective. In the 14 years between 2004 and 2018, the grandiose claims of comparative literature have been problematized and addressed; the lay of the land, however, remains predominantly Eurocentric, as it still focuses on content disproportionately. In this paper, through a study of English translations of Khayyam’s Rubaiyat, and taking Chow’s argument further, I argue that with its commitment to transfer the form of a text as much as the content, translation studies can further help comparative literature to distance itself from Europe. To exemplify the implication of this, I suggest that a translation of Khayyam’s Rubaiyat from Farsi to English would be more faithful to the original if its translations were to focus on the poem’s form rather than the content. I argue that translating with a focus on form would foreignize Khayyam’s poetry, hence an act of resistance against cultural hegemony.

In the early quatrains of “Rubaiyat,” a poem in Lawrence Joseph's fourth book, into it, The poet adopts a curious perspective for an American poet of Arab ancestry who is intensely critical of American military aggression. Taking on the “eye” of the aggressor, he pulls up the “satellite image of a major / military target, a 3-D journey / into a landscape of hills and valleys.” He follows the lens as it zooms closer to the ground:Zoom in close enough—the shadowsof statues, the swimming pools of palaces …closer—a garden of palm trees,oranges and lemons, chickens, sheep. … (41)

In official and unofficial histories, and in cultural memorializations of the 1971 war for Bangladeshi independence, the treatment of women's experiences—more specifically the unresolved question of acknowledgment of and accountability to birangonas, “war heroines” (or rape survivors)—has met with stunning silence or erasure, on the one hand, or with narratives of abject victimhood, on the other. By contrast, the film Meherjaan (2011) revolves around the stories of four women during and after the war, and most centrally the relationship between a Bengali woman and a Pakistani soldier. In this article, I investigate the anxieties underlying the responses to Meherjaan, particularly in association with themes of trauma—its absence or omnipresence—to nonnormative gender frames of national sexuality, and the notion of loving the Other. Drawing from feminist theories of vulnerability, ethics, and love, I want to explore these themes at two levels: the political message the film transmits, and its aesthetic choices and affects. Finally, I want to comment on the potential of this film, as feminist art, in furthering a dialogue around healing and ethical memorialization in relation to 1971 in Bangladesh.

AbstractSa'id Sarmad's dargah (saint's tomb) dominates the entryway to Delhi's imposing Jama Masjid. But Sarmad was a Jew, both by birth and affirmation. He was also, according to his Rubaiyat, "a follower of the Furqan (i.e., a Sufi), a (Catholic) priest, a (Buddhist) monk, a Jewish rabbi, an infidel, and a Muslim." Indeed, it is hard to imagine a mystic with a more complex confessional identity. This paper explores both Sarmad's apparently contradictory religious self-identification and the complex religious context which Sarmad found in seventeenth-century North India. It will trace Sarmad's spiritual path as it meandered between Judaism, Islam and Hinduism, as recorded in his poetry and in the hagiographical (taskira) traditions which surround him, and will contribute to the discussion of the relationship between the mystic and his or her religion of birth or adoption.

Though Sir William Jones's captivating English version of a ghazal of Hafez, first published in 1771, inspired many translators in the final years of the 18th and early years of the 19th century, none succeeded in producing a living, breathing body of Hafez's work in English. Goethe, of course, lavished his admiration on Hafez in the West–Östliche Divan, and Ralph Waldo Emerson echoed and amplified this praise in America with a number of English translations of von Hammer-Purgstall's German renditions of Hafez. All this attention from trend- and style-setting literary figures did Hafez the favor of creating an interest in and a ready market for translations of his poems. At the same time, however, it burdened him with a literary reputation the expectations of which were difficult for translators to meet. Once FitzGerald's Rubaiyat of Omar Khayyam, perhaps the most successful English verse translation in history, demonstrated the possibility of creating a native English idiom for a poet such as Khayyam, readers' expectations for Hafez only intensified. Though a score of translators have tried their hand at Hafez, none has managed anything more than a satisfactory result.

This research is presented to discuss about the imagery of the poetry entitled “The Rubaiyat”. The Rubaiyat is a poem in the 11th century written by a Persian poet named Omar Khayyam. One of the poets who had translated the poem "The Rubaiyat" into English was Edward FitzGerald in 1859, which attracted much controversy. The Rubaiyat is a poem containing with the religious teachings and philosophical symbols that produce a harmonious effect. In this research, the writer used qualitative method with descriptive approach. The writer used the theory of Imagery in analyzing the use of imagery in the poetry relating the idea of carpe diem. Furthermore; the writer collects the data from the poem “The Rubaiyat” written by Omar and classify the kinds of imagery refers to carpe diem ideas that can be found in the poem

The article provides data on the manuscripts and studies of the legacy of Amir Khusrow Dehlavi, stored in the Institute of Oriental Studies named after Abu Rayhan Biruni of the Academy of Sciences of the Republic of Uzbekistan. In the manuscripts we examined, there is information about the origin of ghazals, but there is no mention of the origin of the ruba’is. In many manuscripts, the order of fling the ruba’is is not based on any principle. Only a few of them are arranged alphabetically, either by the frst letter of the verse or by the last letter of the rhyme. It should be noted that the mixed order of transmission of the ruba’is in fve divans in the manuscripts involved in the study can be explained by the long-standing tendency of the poet’s attempts to include them in the framework of one collection. As the main sources of research under the heading of Amir Khusrow Dehlavi can be used the manuscripts of the poet’s works stored at the Abu Rayhan Biruni Institute of Oriental Studies of the Academy of Sciences of the Republic of Uzbekistan. The study of these sources will help to address the gaps in the available publications and to bring the ruba’is to a fuller scale. The materials concerning the rubaiyat of Amir Khusrow Dehlavi, published in Kanpur, Tehran, Dushanbe, do not fully cover the works of the poet of this genre. Therefore, they can only be used as auxiliary resources for research. Our research on the ruba’is of Dehlavi shows that the manuscripts of the Abu Reikhan Biruni Institute of Oriental Studies are reliable and important sources for compiling a complete collection of poetry in this genre. The opinions of previous and current researchers of works about the impossibility of compiling a complete collection of the poetic heritage of Amir Khusrow Dehlavi also apply to his ruba’is. But our research shows that it is possible to create the largest collection of Amir Khusrov Dehlavi’s ruba’is based on the poet’s manuscripts from the funds of Uzbekistan. The large number of handwritten copies of the works of Amir Khusrow Dehlavi allows us to determine when and how many works of this genre were copied, which makes it possible to carry out further research in this area.

ubai is one of the most technical, difficult and short genre of Urdu and Persian literature. It comprises four Misras and as such the poet is compelled to express his view in very limited words. Another difficulty is its rhyme scheme. Rubai comprises 24 specific forms of Behre Hazaj Musamman. The poet can choose any of the four rhymes out of the 24 forms, which can cause problems both for the poet and the readers. In this research paper, the researchers have discussed problems pertaining to art, techniques and difficulties of Rubaiat.

The TRP superfamily of channels (nomenclature as agreed by NC-IUPHAR [145, 915]), whose founder member is the Drosophila Trp channel, exists in mammals as six families; TRPC, TRPM, TRPV, TRPA, TRPP and TRPML based on amino acid homologies. TRP subunits contain six putative transmembrane domains and assemble as homo- or hetero-tetramers to form cation selective channels with diverse modes of activation and varied permeation properties (reviewed by [630]). Established, or potential, physiological functions of the individual members of the TRP families are discussed in detail in the recommended reviews and in a number of books [344, 589, 979, 216]. The established, or potential, involvement of TRP channels in disease is reviewed in [384, 588] and [591], together with a special edition of Biochemica et Biophysica Acta on the subject [588]. Additional disease related reviews, for pain [542], stroke [967], sensation and inflammation [843], itch [109], and airway disease [261, 896], are available. The pharmacology of most TRP channels has been advanced in recent years. Broad spectrum agents are listed in the tables along with more selective, or recently recognised, ligands that are flagged by the inclusion of a primary reference. See Rubaiy (2019) for a review of pharmacological tools for TRPC1/C4/C5 channels [692]. Most TRP channels are regulated by phosphoinostides such as PtIns(4,5)P2 although the effects reported are often complex, occasionally contradictory, and likely to be dependent upon experimental conditions, such as intracellular ATP levels (reviewed by [862, 592, 689]). Such regulation is generally not included in the tables.When thermosensitivity is mentioned, it refers specifically to a high Q10 of gating, often in the range of 10-30, but does not necessarily imply that the channel's function is to act as a 'hot' or 'cold' sensor. In general, the search for TRP activators has led to many claims for temperature sensing, mechanosensation, and lipid sensing. All proteins are of course sensitive to energies of binding, mechanical force, and temperature, but the issue is whether the proposed input is within a physiologically relevant range resulting in a response. TRPA (ankyrin) familyTRPA1 is the sole mammalian member of this group (reviewed by [246]). TRPA1 activation of sensory neurons contribute to nociception [356, 763, 516]. Pungent chemicals such as mustard oil (AITC), allicin, and cinnamaldehyde activate TRPA1 by modification of free thiol groups of cysteine side chains, especially those located in its amino terminus [491, 47, 311, 493]. Alkenals with α, β-unsaturated bonds, such as propenal (acrolein), butenal (crotylaldehyde), and 2-pentenal can react with free thiols via Michael addition and can activate TRPA1. However, potency appears to weaken as carbon chain length increases [21, 47]. Covalent modification leads to sustained activation of TRPA1. Chemicals including carvacrol, menthol, and local anesthetics reversibly activate TRPA1 by non-covalent binding [364, 438, 923, 922]. TRPA1 is not mechanosensitive under physiological conditions, but can be activated by cold temperatures [365, 175]. The electron cryo-EM structure of TRPA1 [639] indicates that it is a 6-TM homotetramer. Each subunit of the channel contains two short ‘pore helices’ pointing into the ion selectivity filter, which is big enough to allow permeation of partially hydrated Ca2+ ions. TRPC (canonical) familyMembers of the TRPC subfamily (reviewed by [239, 673, 14, 4, 79, 382, 638, 55]) fall into the subgroups outlined below. TRPC2 is a pseudogene in humans. It is generally accepted that all TRPC channels are activated downstream of Gq/11-coupled receptors, or receptor tyrosine kinases (reviewed by [661, 814, 915]). A comprehensive listing of G-protein coupled receptors that activate TRPC channels is given in [4]. Hetero-oligomeric complexes of TRPC channels and their association with proteins to form signalling complexes are detailed in [14] and [383]. TRPC channels have frequently been proposed to act as store-operated channels (SOCs) (or compenents of mulimeric complexes that form SOCs), activated by depletion of intracellular calcium stores (reviewed by [640, 14, 665, 703, 954, 132, 626, 51, 133]). However, the weight of the evidence is that they are not directly gated by conventional store-operated mechanisms, as established for Stim-gated Orai channels. TRPC channels are not mechanically gated in physiologically relevant ranges of force. All members of the TRPC family are blocked by 2-APB and SKF96365 [295, 294]. Activation of TRPC channels by lipids is discussed by [55]. Important progress has been recently made in TRPC pharmacology [692, 529, 372, 87]. TRPC channels regulate a variety of physiological functions and are implicated in many human diseases [248, 56, 759, 879]. TRPC1/C4/C5 subgroup TRPC1 alone may not form a functional ion channel [191]. TRPC4/C5 may be distinguished from other TRP channels by their potentiation by micromolar concentrations of La3+. TRPC2 is a pseudogene in humans, but in other mammals appears to be an ion channel localized to microvilli of the vomeronasal organ. It is required for normal sexual behavior in response to pheromones in mice. It may also function in the main olfactory epithelia in mice [951, 625, 624, 952, 462, 988, 947].TRPC3/C6/C7 subgroup All members are activated by diacylglycerol independent of protein kinase C stimulation [295].TRPM (melastatin) familyMembers of the TRPM subfamily (reviewed by [230, 294, 640, 978]) fall into the five subgroups outlined below. TRPM1/M3 subgroupIn darkness, glutamate released by the photoreceptors and ON-bipolar cells binds to the metabotropic glutamate receptor 6 , leading to activation of Go . This results in the closure of TRPM1. When the photoreceptors are stimulated by light, glutamate release is reduced, and TRPM1 channels are more active, resulting in cell membrane depolarization. Human TRPM1 mutations are associated with congenital stationary night blindness (CSNB), whose patients lack rod function. TRPM1 is also found melanocytes. Isoforms of TRPM1 may present in melanocytes, melanoma, brain, and retina. In melanoma cells, TRPM1 is prevalent in highly dynamic intracellular vesicular structures [341, 609]. TRPM3 (reviewed by [615]) exists as multiple splice variants which differ significantly in their biophysical properties. TRPM3 is expressed in somatosensory neurons and may be important in development of heat hyperalgesia during inflammation (see review [803]). TRPM3 is frequently coexpressed with TRPA1 and TRPV1 in these neurons. TRPM3 is expressed in pancreatic beta cells as well as brain, pituitary gland, eye, kidney, and adipose tissue [614, 802]. TRPM3 may contribute to the detection of noxious heat [870].TRPM2TRPM2 is activated under conditions of oxidative stress (respiratory burst of phagocytic cells) and ischemic conditions. However, the direct activators are ADPR(P) and calcium. As for many ion channels, PIP2 must also be present (reviewed by [935]). Numerous splice variants of TRPM2 exist which differ in their activation mechanisms [200]. The C-terminal domain contains a TRP motif, a coiled-coil region, and an enzymatic NUDT9 homologous domain. TRPM2 appears not to be activated by NAD, NAAD, or NAADP, but is directly activated by ADPRP (adenosine-5'-O-disphosphoribose phosphate) [827]. TRPM2 is involved in warmth sensation [724], and contributes to neurological diseases [61]. Recent study shows that 2'-deoxy-ADPR is an endogenous TRPM2 superagonist [231]. TRPM4/5 subgroupTRPM4 and TRPM5 have the distinction within all TRP channels of being impermeable to Ca2+ [915]. A splice variant of TRPM4 (i.e.TRPM4b) and TRPM5 are molecular candidates for endogenous calcium-activated cation (CAN) channels [278]. TRPM4 is active in the late phase of repolarization of the cardiac ventricular action potential. TRPM4 deletion or knockout enhances beta adrenergic-mediated inotropy [507]. Mutations are associated with conduction defects [347, 507, 753]. TRPM4 has been shown to be an important regulator of Ca2+ entry in to mast cells [847] and dendritic cell migration [39]. TRPM5 in taste receptor cells of the tongue appears essential for the transduction of sweet, amino acid and bitter stimuli [460] TRPM5 contributes to the slow afterdepolarization of layer 5 neurons in mouse prefrontal cortex [439]. Both TRPM4 and TRPM5 are required transduction of taste stimuli [206].TRPM6/7 subgroupTRPM6 and 7 combine channel and enzymatic activities (‘chanzymes’). These channels have the unusual property of permeation by divalent (Ca2+, Mg2+, Zn2+) and monovalent cations, high single channel conductances, but overall extremely small inward conductance when expressed to the plasma membrane. They are inhibited by internal Mg2+ at ~0.6 mM, around the free level of Mg2+ in cells. Whether they contribute to Mg2+ homeostasis is a contentious issue. When either gene is deleted in mice, the result is embryonic lethality. The C-terminal kinase region is cleaved under unknown stimuli, and the kinase phosphorylates nuclear histones. TRPM7 is responsible for oxidant- induced Zn2+ release from intracellular vesicles [3] and contributes to intestinal mineral absorption essential for postnatal survival [532]. TRPM8Is a channel activated by cooling and pharmacological agents evoking a ‘cool’ sensation and participates in the thermosensation of cold temperatures [50, 147, 186] reviewed by [864, 481, 391, 556]. TRPML (mucolipin) familyThe TRPML family [676, 964, 670, 926, 156] consists of three mammalian members (TRPML1-3). TRPML channels are probably restricted to intracellular vesicles and mutations in the gene (MCOLN1) encoding TRPML1 (mucolipin-1) cause the neurodegenerative disorder mucolipidosis type IV (MLIV) in man. TRPML1 is a cation selective ion channel that is important for sorting/transport of endosomes in the late endocytotic pathway and specifically, fission from late endosome-lysosome hybrid vesicles and lysosomal exocytosis [704]. TRPML2 and TRPML3 show increased channel activity in low extracellular sodium and are activated by similar small molecules [270]. A naturally occurring gain of function mutation in TRPML3 (i.e. A419P) results in the varitint waddler (Va) mouse phenotype (reviewed by [676, 593]). TRPP (polycystin) familyThe TRPP family (reviewed by [179, 177, 252, 905, 320]) or PKD2 family is comprised of PKD2 (PC2), PKD2L1 (PC2L1), PKD2L2 (PC2L2), which have been renamed TRPP1, TRPP2 and TRPP3, respectively [915]. It should also be noted that the nomenclature of PC2 was TRPP2 in old literature. However, PC2 has been uniformed to be called TRPP2 [293]. PKD2 family channels are clearly distinct from the PKD1 family, whose function is unknown. PKD1 and PKD2 form a hetero-oligomeric complex with a 1:3 ratio. [775]. Although still being sorted out, TRPP family members appear to be 6TM spanning nonselective cation channels. TRPV (vanilloid) familyMembers of the TRPV family (reviewed by [849]) can broadly be divided into the non-selective cation channels, TRPV1-4 and the more calcium selective channels TRPV5 and TRPV6.TRPV1-V4 subfamilyTRPV1 is involved in the development of thermal hyperalgesia following inflammation and may contribute to the detection of noxius heat (reviewed by [660, 756, 786]). Numerous splice variants of TRPV1 have been described, some of which modulate the activity of TRPV1, or act in a dominant negative manner when co-expressed with TRPV1 [722]. The pharmacology of TRPV1 channels is discussed in detail in [280] and [868]. TRPV2 is probably not a thermosensor in man [635], but has recently been implicated in innate immunity [469]. TRPV3 and TRPV4 are both thermosensitive. There are claims that TRPV4 is also mechanosensitive, but this has not been established to be within a physiological range in a native environment [106, 454].TRPV5/V6 subfamily TRPV5 and TRPV6 are highly expressed in placenta, bone, and kidney. Under physiological conditions, TRPV5 and TRPV6 are calcium selective channels involved in the absorption and reabsorption of calcium across intestinal and kidney tubule epithelia (reviewed by [901, 168, 558, 227]).