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Journal articles on the topic "RPE"

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Brink, Michel S., Anna W. Kersten, and Wouter G. P. Frencken. "Understanding the Mismatch Between Coaches’ and Players’ Perceptions of Exertion." International Journal of Sports Physiology and Performance 12, no. 4 (April 2017): 562–68. http://dx.doi.org/10.1123/ijspp.2016-0215.

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A mismatch between the training exertion intended by a coach and the exertion perceived by players is well established in sports. However, it is unknown whether coaches can accurately observe exertion of individual players during training. Furthermore, the discrepancy in coaches’ and players’ perceptions has not been explained.Purpose:To determine the relation between intended and observed training exertion by the coach and perceived training exertion by the players and establish whether on-field training characteristics, intermittent endurance capacity, and maturity status explain the mismatch.Methods:During 2 mesocycles of 4 wk (in November and March), rating of intended exertion (RIE), rating of observed exertion (ROE), and rating of perceived exertion (RPE) were monitored in 31 elite young soccer players. External and internal training loads were objectively quantified with accelerometers (PlayerLoad) and heart-rate monitors (TRIMPmod). Results of an interval shuttle-run test (ISRT) and age at peak height velocity (APHV) were determined for all players.Results:RIE, ROE, and RPE were monitored in 977 training sessions. The correlations between RIE and RPE (r = .58; P < .01) and between ROE and RPE (r = .64; P < .01) were moderate. The mean difference between RIE and RPE was –0.31 ± 1.99 and between ROE and RPE was –0.37 ± 1.87. Multilevel analyses showed that PlayerLoad and ISRT predicted RIE and ROE.Conclusion:Coaches base their intended and observed exertion on what they expect players will do and what they actually did on the field. When doing this, they consider the intermittent endurance capacity of individual players.
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Susilowati, Lolita Endang, Uyek Malik Yakop, Lestari Ujianto, and Bambang Hari Kusumo. "The Nutrient Uptake Efficiency, Crop Productivity and Quality of Rice Bean in Dry Land." JOURNAL OF TROPICAL SOILS 20, no. 1 (January 29, 2016): 1. http://dx.doi.org/10.5400/jts.2015.v20i1.1-9.

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Rice bean is a group of beans that are rich in carbohydrates, proteins and fats. This plant is resistant to pests and diseases, as well as the broad adaptability. This study aims to obtain an efficient fertilization pattern on rice bean cultivation in dry land. The treatments consisted of 9 fertilization patterns which were RP0: no fertilizer (control); RP1: 100% recommendation fertilizer (50 kg Urea and 100 kg SP-36 ha-1); RP2: 5 Mg ha-1 manure plus 50% recommendation fertilizer; RP3: RP2 plus MVA; RP4: 5 Mg ha-1 Crotalaria sp compost plus 50% recommendation fertilizer; RP5: RP4 plus VAM; RP6: 2.5 t ha-1 manure, 2.5 Mg ha-1 Crotalaria sp compost plus 50% recommendation fertilizer; RP7: 1.5 Mg ha-1 manure, 1 Mg ha-1 Crotalaria sp compost plus 50% recommendation fertilizer; RP8: RP7 plus MVA. Fertilization treatments were arranged in RCBD and each treatment was repeated 3 times. The fertilization treatments had no significant effect on NUE. Productivity of rice bean in RP3 and RP5 reached 3.75 Mg ha-1, in RP2 and RP4 achieved 2.64 Mg ha-1, and in the control treatment reached 1.94 Mg ha-1. Carbohydrate content in seeds increased by 20% in the fertilization treatments compared to the control. Protein and anthocyanin content in all treatments were not significantly different. The combination of 5 Mg organic fertilizer (manure and / or Crotalaria compost), 50% recommendation fertilizer plus MVA was an efficient fertilization pattern to improve P fertilizer uptake efficiency (PUE), productivity and quality of rice bean crop in dry land. [How to Cite: Lolita ES, UM Yakop, L Ujianto, and B Hari Kusumo. 2015. The Nutrient Uptake Efficiency, Crop Productivity and Quality of Rice Bean in Dry Land. J Trop Soils 19: 1-9. Doi: 10.5400/jts.2015.20.1.1][Permalink/DOI: www.dx.doi.org/10.5400/jts.2015.20.1.1]
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Soto, Juvenal, and Mark Aldrich. "RPE / RPE." Sirena: poesia, arte y critica 2006, no. 2 (2006): 130–33. http://dx.doi.org/10.1353/sir.2006.0171.

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Vinores, S. A., R. McGehee, A. Lee, C. Gadegbeku, and P. A. Campochiaro. "Ultrastructural localization of blood-retinal barrier breakdown in diabetic and galactosemic rats." Journal of Histochemistry & Cytochemistry 38, no. 9 (September 1990): 1341–52. http://dx.doi.org/10.1177/38.9.2117624.

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Breakdown of the blood-retinal barrier (BRB) is an early event in diabetic and galactosemic rats, but the location and nature of the specific defect(s) are controversial. Using an electron microscopic immunocytochemical technique, the retinas of normal, diabetic, and galactosemic rats were immunostained for endogenous albumin. Normal rats showed little evidence of BRB breakdown at either the inner barrier (retinal vasculature) or the outer barrier (retinal pigment epithelium) (RPE). In diabetic and galactosemic rats, as was true in human diabetics, BRB breakdown occurred predominantly at the inner BRB, but in some cases at the outer barrier as well. Treatment with the aldose reductase inhibitor sorbinil largely prevented BRB failure in galactosemic rats. In the inner retina of diabetic and galactosemic rats, albumin was frequently demonstrated on the abluminal side of the retinal capillary endothelium (RCE) in intercellular spaces, basal laminae, pericytes, ganglion cells, astrocytes, and the perinuclear cytoplasm of cells in the inner nuclear layer. Albumin did not appear to cross RCE cell junctions; however, it was occasionally seen in RCE cytoplasm of galactosemic rats. In the outer retina, albumin was frequently detected in the subretinal space, in the intercellular space between photoreceptors, and in the perinuclear cytoplasm of photoreceptor cells, but was only infrequently found in the RPE cells constituting the barrier. Albumin derived from the choroidal vasculature did not appear to cross the tight junctions of the RPE. These findings suggest that specific sites of BRB compromise are infrequent but that once albumin has crossed the RCE or RPE it freely permeates the retinal tissue by filling intercellular spaces and permeating the membranes of cells not implicated in BRB formation. The diffuse cytoplasmic staining of some RCE and RPE cells suggests that the predominant means of BRB breakdown in diabetes and galactosemia involves increased focal permeability of the surface membranes of the RCE and RPE cells rather than defective tight junctions or vesicular transport.
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Horner, Faye, James Wawrzynski, and Robert MacLaren. "Novel non-sense mutation in RP2 (c.843_844insT/p.Arg282fs) is associated with a severe phenotype of retinitis pigmentosa without evidence of primary retinal pigment epithelium involvement." BMJ Case Reports 12, no. 5 (May 2019): e224451. http://dx.doi.org/10.1136/bcr-2018-224451.

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Retinitis pigmentosa (RP) relates to a heterogeneous group of rod-cone dystrophies of varying genetic aetiology. There is currently great interest in gene replacement therapy. Phenotyping is of particular importance because some RP genes are expressed ubiquitously and it is critically important to understand which retinal layer is primarily affected. RP2 is increasingly diagnosed in patients suffering from X-linked RP, which causes outer retinal degeneration. We present a case of a previously unreported null mutation in RP2 associated with severe RP. Loss of the retinal pigment epithelium (RPE) was noted in the central macula but not around the disc or peripherally. There was therefore no evidence of independent degeneration of the RPE. Hence despite expression in all retinal cells, RP2 deficiency does not appear to be pathogenic to the RPE. This observation may be helpful in considering the promoter and route of delivery of adeno-associated viral gene therapy vectors encoding RP2.
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Xu, Z., S. Rafi, and W. Ramakrishna. "Polymorphisms and evolutionary history of retrotransposon insertions in rice promoters." Genome 54, no. 8 (August 2011): 629–38. http://dx.doi.org/10.1139/g11-030.

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Retrotransposons are ubiquitous in higher plant genomes. The presence or absence of retrotransposons in whole genome and high throughput genomic sequence (HTGS) from cultivated and wild rice was investigated to understand the organization and evolution of retrotransposon insertions in promoter regions. Approximately half of the Oryza sativa subsp. japonica ‘Nipponbare’ promoters with retrotransposons conserved in Oryza sativa subsp. indica ‘93-11’ and four wild rice species showed higher sequence conservation in retrotransposon than nonretrotransposon regions. We further investigated, in detail, the evolutionary dynamics of five retrotransposons in the promoter regions of 95 rice genotypes. Our data suggest that four of five insertions (Rp2–Rp5) occurred in the ancestor of AA genome, while the other insertion (Rp1) predates the ancestral divergence of Oryza officinalis (CC genome). Four retrotransposons (Rp2–Rp5) were present in 52% (Rp2), 29% (Rp3), 53% (Rp4), and 43% (Rp5) of the rice genotypes with AA genome type, and the fifth retrotransposon (Rp1) was present in 95% of the rice genotypes with AA, BBCC, or CC genome types. Furthermore, most of these retrotransposons were found to evolve slower than flanking promoter regions, suggesting a role in promoter function for regulating downstream genes.
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Pritchett, R. C., J. M. Green, T. R. Crews, R. Deere, D. C. Tucker, and J. R. McLester. "RPE." Medicine & Science in Sports & Exercise 35, Supplement 1 (May 2003): S287. http://dx.doi.org/10.1097/00005768-200305001-01598.

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Dwyer, Gregory B., Milchell H. Whaley, and Leonard A. Kaminsky. "FREQUENCY OF RPE INQUIRIES EFFECTS THE RPE." Journal of Cardiopulmonary Rehabilitation 12, no. 5 (September 1992): 360. http://dx.doi.org/10.1097/00008483-199209000-00059.

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Hornsby, Jared H., James M. Green, Eric K. O’Neal, Lauren L. Killen, Joyce R. McIntosh, and Tom E. Coates. "Influence of Terminal RPE on Session RPE." Journal of Strength and Conditioning Research 27, no. 10 (October 2013): 2800–2805. http://dx.doi.org/10.1519/jsc.0b013e3182830d6c.

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Demura, Shinichi, and Yoshinori Nagasawa. "Relations between Perceptual and Physiological Response during Incremental Exercise Followed by an Extended Bout of Submaximal Exercise on a Cycle Ergometer." Perceptual and Motor Skills 96, no. 2 (April 2003): 653–63. http://dx.doi.org/10.2466/pms.2003.96.2.653.

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The purpose of this study was to examine the relations of ratings of perceived exertion (RPE) of the legs, chest, and overall body with physiological responses (heart rate and oxygen uptake) both during incremental cycling exercise and the recovery stage (submaximal light exercise after total exhaustion). Subjects were 10 healthy university males ages 18 to 23 years ( M age = 20.5 yr., SD= 1.4 yr.) who performed incremental cycling exercise until exhaustion after 1-min. rest and unloaded cycling for 2 min. They then continued to exercise at a constant load of 30 Watts (used for cooling down; recovery stage) for a total of 25 min. Oxygen uptake and heart rate were measured, and three types of RPE were done; Respiratory (chest; RPE-R), Peripheral (legs; RPE-P), and Overall (overall body; RPE-O) during the exercise and recovery stage. All variables during exercise and RPE-R and RPE-P during recovery stage showed significant linear changes. RPE-O and physiological exercise intensity (oxygen uptake and heart rate) in the recovery stage showed significant curvilinear changes (quadratic). RPE-P were significantly higher than RPE-R both during exercise and the recovery stage and the variables highly correlated ( r ≥.88, p <.05). At the point of exhaustion, RPE-P and RPE-O almost reached a peak, but RPE-R did not. In the exercise period until exhaustion, the regression coefficient of RPE-R (.38) was significantly lower than that of RPE-P (.56) and RPE-O (.50), and RPE-R increased according to an increase of the incremental load, but the amount was significantly lower than those of RPE-P and RPE-O. In the recovery stage after exhaustion, the regression coefficient of RPE-O (−1.35) was significantly greater than that of RPE-P (−1.07). A decrease in RPE-O corresponded to a decrease in heart rate and oxygen uptake, but RPE-P did not, and the recovery of RPE-P tended to be late. The results suggest that relations for the physiological responses of heart rate, oxygen uptake, and RPE, and between each RPE in the recovery stage differed from those during exercise until exhaustion.
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Dissertations / Theses on the topic "RPE"

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Graffunder, Corinne Meltzer Weiner Bryan J. "Strengthening the prevention support system in CDC's Rape Prevention and Education RPE program." Chapel Hill, N.C. : University of North Carolina at Chapel Hill, 2008. http://dc.lib.unc.edu/u?/etd,2093.

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Thesis (DrPH)--University of North Carolina at Chapel Hill, 2008.
Title from electronic title page (viewed Feb. 17, 2009). "... in partial fulfillment of the requirements for the degree of Doctor of Public Health in the Department of Public Health." Discipline: Public Health; Department/School: Public Health.
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Niang, Awa. "RPE et relaxation de composites moléculaires bidimensionnels." Toulouse 3, 1994. http://www.theses.fr/1994TOU30153.

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Nous avons etudie par resonance paramagnetique electronique en bande x l'anisotropie de la largeur de raie et du facteur g des composites moleculaires bidimensionnels de type perovskite feuillete nh#3-r-nh#3mx#4. Les mesures ont ete effectuees sur des monocristaux et des poudres en fonction de la temperature (de 4. 2 a 290k). Le temps de relaxation spin-reseau t#1 a egalement ete mesure par la methode de modulation en fonction de la temperature. Les echantillons presentent des structures et des interactions de couplage differentes suivant la nature de l'halogene x, du metal m et du radical organique r. Nous avons analyse l'influence de ces parametres sur le comportement des spins par l'etude des echantillons nh#3-(ch#2)#n-nh#3mx#4 m = (manganese, cuivre. ), x (chlore, brome) et n = 2,3,4,5. Lorsque r est compose de molecules ayant des liaisons insaturees ces materiaux constituent d'excellentes matrices pour des reactions de polymerisation selectives par irradiation ou par traitement thermique. Nous avons effectue des mesures de rpe et de relaxation spin-reseau sur le complexe de propargylamine et de chlorure de cadmium hcc-ch#2-nh#3#2cdcl#4 chauffe. L'interpretation des resultats s'effectue en tenant compte de la forte interaction d'echange presente dans ces echantillons et des differentes interactions de couplage. Les dependances de t#1 sont interpretees en utilisant le modele des trois reservoirs de bloembergen et wang. Les resultats mettent en evidence la diffusion des spins lorsque le metal est le manganese et la presence d'une interaction d'echange antisymetrique modulee par les phonons dans le cas du cuivre. La nature de l'halogene joue egalement un role important dans la dynamique des spins et notamment dans la relaxation spin-reseau. Les resultats obtenus sur hcc-ch#2-nh#3#2cdcl#4 chauffe sous vide mettent en evidence la creation d'un nombre important de centres paramagnetiques due a la disparition des triples liaisons et par consequent une forte interaction d'echange
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Assis, Alice [UNESP]. "Ressonância paramagnética eletrônica (RPE) aplicada em semicondutores orgânicos." Universidade Estadual Paulista (UNESP), 2012. http://hdl.handle.net/11449/99662.

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
Um importante fator para a vida útil de dispositivos emissores de luz que utilizam compostos organometálicos como material emissor é a compreensão do seu mecanismo de degradação. O principal mecanismo de degradação destes materiais é a dissociação reversível/irreversível entre o átomo metálico central e um de seus ligantes após a excitação da molécula emissora. O complexo de carga formado em decorrência da dissociação irreversível pode ser sensível a campos magnéticos aplicados, através da interação do campo com o elétron desemparelhado. Desta forma, neste trabalho foram avaliados, através de medidas de ressonância paramagnética eletrônica (RPE), os possíveis processos de degradação em sistemas contendo a dispersão de dois compostos organometálicos fac tris(2-fenilpiridina) irídico (ir(ppy)3) e irídio bis(4,6-diflúorfenil)-piridinato-N, C2) picolinato (Flrpic) em diferentes matizes poliméricas como o poliestireno (PS), o poli(9,9-dioctifluoreno-2,7-dil) (PFO) e o polimetilmetacrilato (PMMA). Foi avaliada ainda a influência da molécula doadora de cargas 1,2,4,5-tetracianobenzeno (TCNB) na dispersão Flrpic+PS. Os processos de degradação foram estudados através da análise de diversos parâmetros, como o comportamento do sinal de RPE com a fotoexcitação, processo de relaxação do sinal em diferentes temperaturas e à avaliação do sinal de RPE dos compostos organometálicos puros e nas diferenetes dispersões em matizes poliméticas. Os resultados mostraram que um sinal de RPE relativamento baixo é obtido para o composto Flrpic puro. Entretanto a sua inserção em matrizes poliméricas promoveu um aumento significativo da intensidade do sinal. Dados de absorção e emissão óptica dos compostos evidenciaram que espécies excitadas são inicialmente fotogenadas nos complexos metálicos...
Understanding the degradation mechanism of light emitting devices based on organometallic compounds is the major point to improve their life time. The main mechanism of degradation of these materials is the reversible/irreversible dissociation between the central metallic atom and one of its ligands after the excitation of the emiting molecule. The carge complex formed due to the irreversible dissociation may be sensitive to applied magnetic fields through the field interaction with the unpaired electron. Thus, in this study the possible degradation processes in dispersion systems composed by two organometallic compounds Iridium(III)bis(4,6-fluorephenyl)-pyridiano-N, C2]picolinate (Flrpic) and iridium(III)fac-tris(2-phenylpyridine) (Ir (ppy)3) in different polymer matrices (polystyrene (PS), poly(methylmethacrylate) (PMMA) and poly(9,9-dioctylfluorene) (PFO) were analysed through electron paramagnetic resonance (ERP) technique. The influence of a charge donor molecule 1,2,4,5-tetracyanobenzene (TCNB) in Flrpic+PS dispersion was also examined. The processes of degradation were studied by analysing a variety of parameters such as the behaviour or the EPR signal with the photoexcitation, the process of signal relaxation at different temperatures and the evaluation of the EPR signal of pure organometallic compounds and its dispersion in different polymeric matrices. The results showed that a relatively low EPR signal is obtained for pure Flrpic compound. However its insertion in polymeric matrices caused a significant increase in the signal intensity. The optical absorption and emission data have shown that the excited species are initially photogenerated in metal complexes of those compounds, promoting the subsequent formation of paramagnetic centres, close to Indium atom. The energy levels analysis also suggests an exciton trapping process, which were associated with... (Complete abstract click electronic access below)
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Stein, Roberto de Mello. "RPE em compostos de grafite intercalado com ALCL3." [s.n.], 1985. http://repositorio.unicamp.br/jspui/handle/REPOSIP/277549.

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Orientador: Carlos Rettori
Tese (doutorado) - Universidade Estadual de Campinas, Instituto de Fisica Gleb Wataghin
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Resumo: Nós mostramos que no Composto de Grafite Intercalado com AlCl3, tipo aceitador, a dependência com a temperatura da resistividade no plano e na direção do eixo-c entre 100K e 300K, pode ser obtida experimentalmente através da análise da intensidade e da forma da linha da ressonância de spin dos portadores de carga. Os resultados indicam um comportamento metálico e do tipo salto por ativação térmica para o transporte de carga no plano e no eixo-c, respectivamente. A análise da ressonância no grafite puro apresenta dentro do erro experimental, a dependência com a temperatura esperada para a resistividade no plano e no eixo-c e uma susceptibilidade que independe da temperatura. A dependência da largura da linha é atribuída a dependência com a temperatura da mobilidade dos portadores e da razão entre a probabilidade de transição para "spin-flip" devido ao acoplamento spin-órbita e o espalhamento coulombiano. Para estágios um e sete os parâmetros da ressonância revelam uma transição de fase a 210K e 168K respectivamente
Abstract: We show that the temperature dependence of the in-plane and c-axis resitivities between 100K and 300K for the acceptor AlCl3 - Graphite Intercalated Compounds can be obtained from the analysis of the intensity and lineshape of the resonance in a conduction carrier spin resonance experiment. The results suggest a metallic and thermal activated hopping like character for the in-plane and c-axis charge transport respectively. The analysis of the resonance for pure graphite gives, within the experimental accuracy, the expected temperature dependence for the in-plane and c-axis resistivities, and an almost temperature independent Pauli paramagnetic susceptibility. The temperature dependence of the linewidth is attributed to the dependence of both the carrier s mobility and the ratio between the transition probability for spin-flip due to spin-orbit coupling and the coulomb scattering. For stage one and seven the resonance parameters reveal a phase transition at 210K and 168K respectively
Doutorado
Física
Doutor em Ciências
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Assis, Andrei Paulo de. "Ressonância paramagnética eletrônica (RPE) aplicada em semicondutores orgânicos /." Bauru, 2012. http://hdl.handle.net/11449/99662.

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Orientador: Carlos Frederico de Oliveira Graeff
Banca: Claudio José Magon
Banca: José Humberto Dias da Silva
O Programa de Pós Graduação em Ciência e Tecnologia de Materiais, POSMAT, tem caráter institucional e integra as atividades de pesquisa em materiais em diversos campi
Resumo: Um importante fator para a vida útil de dispositivos emissores de luz que utilizam compostos organometálicos como material emissor é a compreensão do seu mecanismo de degradação. O principal mecanismo de degradação destes materiais é a dissociação reversível/irreversível entre o átomo metálico central e um de seus ligantes após a excitação da molécula emissora. O complexo de carga formado em decorrência da dissociação irreversível pode ser sensível a campos magnéticos aplicados, através da interação do campo com o elétron desemparelhado. Desta forma, neste trabalho foram avaliados, através de medidas de ressonância paramagnética eletrônica (RPE), os possíveis processos de degradação em sistemas contendo a dispersão de dois compostos organometálicos fac tris(2-fenilpiridina) irídico (ir(ppy)3) e irídio bis(4,6-diflúorfenil)-piridinato-N, C2) picolinato (Flrpic) em diferentes matizes poliméricas como o poliestireno (PS), o poli(9,9-dioctifluoreno-2,7-dil) (PFO) e o polimetilmetacrilato (PMMA). Foi avaliada ainda a influência da molécula doadora de cargas 1,2,4,5-tetracianobenzeno (TCNB) na dispersão Flrpic+PS. Os processos de degradação foram estudados através da análise de diversos parâmetros, como o comportamento do sinal de RPE com a fotoexcitação, processo de relaxação do sinal em diferentes temperaturas e à avaliação do sinal de RPE dos compostos organometálicos puros e nas diferenetes dispersões em matizes poliméticas. Os resultados mostraram que um sinal de RPE relativamento baixo é obtido para o composto Flrpic puro. Entretanto a sua inserção em matrizes poliméricas promoveu um aumento significativo da intensidade do sinal. Dados de absorção e emissão óptica dos compostos evidenciaram que espécies excitadas são inicialmente fotogenadas nos complexos metálicos...
Abstract: Understanding the degradation mechanism of light emitting devices based on organometallic compounds is the major point to improve their life time. The main mechanism of degradation of these materials is the reversible/irreversible dissociation between the central metallic atom and one of its ligands after the excitation of the emiting molecule. The carge complex formed due to the irreversible dissociation may be sensitive to applied magnetic fields through the field interaction with the unpaired electron. Thus, in this study the possible degradation processes in dispersion systems composed by two organometallic compounds Iridium(III)bis(4,6-fluorephenyl)-pyridiano-N, C2]picolinate (Flrpic) and iridium(III)fac-tris(2-phenylpyridine) (Ir (ppy)3) in different polymer matrices (polystyrene (PS), poly(methylmethacrylate) (PMMA) and poly(9,9-dioctylfluorene) (PFO) were analysed through electron paramagnetic resonance (ERP) technique. The influence of a charge donor molecule 1,2,4,5-tetracyanobenzene (TCNB) in Flrpic+PS dispersion was also examined. The processes of degradation were studied by analysing a variety of parameters such as the behaviour or the EPR signal with the photoexcitation, the process of signal relaxation at different temperatures and the evaluation of the EPR signal of pure organometallic compounds and its dispersion in different polymeric matrices. The results showed that a relatively low EPR signal is obtained for pure Flrpic compound. However its insertion in polymeric matrices caused a significant increase in the signal intensity. The optical absorption and emission data have shown that the excited species are initially photogenerated in metal complexes of those compounds, promoting the subsequent formation of paramagnetic centres, close to Indium atom. The energy levels analysis also suggests an exciton trapping process, which were associated with...
Mestre
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Zhang, Youwen, Samuel D. Cross, James B. Stanton, Alan D. Marmorstein, Yun Zheng Le, and Lihua Y. Marmorstein. "Early AMD-like defects in the RPE and retinal degeneration in aged mice with RPE-specific deletion of Atg5 or Atg7." MOLECULAR VISION, 2017. http://hdl.handle.net/10150/623963.

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Purpose: To examine the effects of autophagy deficiency induced by RPE-specific deletion of Atg5 or Atg7 in mice as a function of age. Methods: Conditional knockout mice with a floxed allele of Atg5 or Atg7 were crossed with inducible VMD2-rtTA/Cre transgenic mice. VMD2-directed RPE-specific Cre recombinase expression was induced with doxycycline feeding in the resulting mice. Cre-mediated deletion of floxed Atg5 or Atg7 resulted in RPE-specific inactivation of the Atg5 or Atg7 gene. Plastic and thin retinal sections were analyzed with light and electron microscopy for histological changes. Photoreceptor outer segment (POS) thickness in plastic sections was measured using the Adobe Photoshop CS4 extended ruler tool. Autophagic adaptor p62/SQSTM1 and markers for oxidatively damaged lipids, proteins, and DNA were examined with immunofluorescence staining of cryosections. Fluorescence signals were quantified using Image J software. Results: Accumulation of p62/SQSTM1 reflecting autophagy deficiency was observed in the RPE of the Atg5(Delta RPE) and Atg7(Delta RP)E mice. 3-nitrotyrosine, advanced glycation end products (AGEs), and 8-hydroxy-2'-deoxyguanosine (8-OHdG), markers for oxidatively damaged proteins and DNA, were also found to accumulate in the RPE of these mice. We observed retinal degeneration in 35% of the Atg5(Delta RPE) mice and 45% of the Atg7.RPE mice at 8 to 24 months old. Degeneration severity and the number of mice with degeneration increased with age. The mean POS thickness of these mice was 25 mu m at 8-12 months, 15 mu m at 13-18 months, and 3 mu m at 19-24 months, compared to 35 mu m, 30 mu m, and 24 aem in the wildtype mice, respectively. Early age-related macular degeneration (AMD)-like RPE defects were found in all the Atg5(Delta RPE) and Atg7.RPE mice 13 months old or older, including vacuoles, uneven RPE thickness, diminished basal infoldings, RPE hypertrophy/hypotrophy, pigmentary irregularities, and necrosis. The severity of the RPE defects increased with age and in the mice with retinal degeneration. RPE atrophy and choroidal neovascularization (CNV) were occasionally observed in the Atg5(Delta RPE) and Atg7(Delta RPE) mice with advanced age. Conclusions: Autophagy deficiency induced by RPE-specific deletion of Atg5 or Atg7 predisposes but does not necessarily drive the development of AMD-like phenotypes or retinal degeneration.
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Gao, Jiangyuan. "NLRP3 inflammasome activity in RPE : role in AMD pathogenesis." Thesis, University of British Columbia, 2017. http://hdl.handle.net/2429/62512.

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Purpose: Age-related macular degeneration (AMD) is a devastating eye disease causing irreversible vision loss in the elderly. Retinal pigment epithelium (RPE), an important cell type afflicted in AMD, undergoes cell death in the late stages of the disease. Salient factors underlying AMD pathogenesis are aging, drusen components and NLRP3 inflammasome activity. The purpose of this dissertation is to elucidate the molecular interactions among these factors and how they contribute to RPE damage. Methods: The effects of aging on drusen components, in particular the membrane attack complex (MAC) and amyloid beta (Aβ) were examined in rats at different age. To determine the role of MAC in inflammasome activation in RPE, aurin tricarboxylic acid complex (ATAC), was administrated to naïve rats. To understand Aβ’s role in inflammasome activation, Aβ intravitreal injections were made into rat eyes in vivo and Vinpocetine was used to ameliorate the inflammatory responses. An in vitro RPE cell culture model was established to further investigate the relationship between inflammasome and X-chromosome linked inhibitor of apoptosis (XIAP). Statistical significance was set at p ≤ 0.05. Results: An age-dependent increase in MAC, Aβ, and NF-κB activation was observed in the RPE-choroid in vivo. Blocking MAC formation with ATAC led to a prominent reduction in inflammasome activity (caspase-1 cleavage and cytokine secretion), but not in NF-κB activity. Aβ intravitreal injections triggered inflammasome activation evidenced by enhanced caspase-1 cleavage and IL-1β/IL-18 release, which was suppressed by Vinpocetine mediated NF-κB inhibition. The robust inflammasome activity further led to gasdermin D-mediated activation of the pyroptotic pathway and a significant reduction in XIAP, which in turn enhanced IL-18 secretion. Conclusion: Aging is a strong risk factor for AMD, which increases the deposition of MAC and Aβ in the outer retina. The elevated levels of MAC and Aβ are triggers for inflammasome activation. By demonstrating a causal relationship between inflammasome activation and XIAP reduction, this dissertation suggests the precise regulation of XIAP, together with the suppression of MAC and NF-κB, may be crucial for controlling inflammasome activity and hence provides new avenues to prevent AMD.
Medicine, Faculty of
Graduate
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Moraes, Itamar Jose. "RPE dos íons Cr3+, Er3+ e Mn2+ em Ca3Ga2Ge3O12." Universidade de São Paulo, 1993. http://www.teses.usp.br/teses/disponiveis/54/54132/tde-08122014-162605/.

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O objetivo principal deste trabalho é o estudo por ressonância paramagnética eletrônica das impurezas Cr3+, Er3+ e Mn3+ no monocristal Ca3Ga2Ge3O12 (denominado CGGG) nas freqüências de 1.3, 10 e 34 GHz e nas temperaturas de 4,2K a 300K. O Hamiltoniano de spin para o Cr3+ alojado no sítio octaédrico com simetria C Cr3i é dado por: H = β[g⊥ (HxSx + HySy) + g‌HzSz] + D (S2z - 1/3 S (S+1). Os parâmetros do Hamiltoniano de spin para o íon Cr3+ em baixas concentrações são: g‌ = 1,9727 ± 0,0003, g⊥ = 1,9617 ± 0,0008 e D = 16,20 ± 0,02GHz para CGGG dopados com o íon Cr3+. Os cristais CGGG, dopados com Er3+ e Cr3+, apresentaram os seguintes parâmetros g‌ = 1,9662 ± 0,0003, g⊥ = 1,9617 ± 0,0008 e D = 15,82 ± 0,02GHz. Os parâmetros do Hamiltoniano de spin efetivo para o íon Er3+ alojado no sítio dodecaédrico e com simetria D2 são: gx = 2,690 ± 0,0005, gy = 4,095 ± 0,005 e gz = 5,082 ± 0,005. Os centros paramagnéticos Mn2+ produzidos em cristais dopados com Cr3+, irradiados com raios X, à temperatura ambiente, apresentam o fator-g isotrópico, g = 2,0066 ± 0,0001 e a constante de interação hiperfina A = 90 Gauss. Medimos, também as dependências das larguras de linhas com a temperatura, nas três bandas e para banda X medimos nas temperaturas de 4,2K até 300K
In this work was studied the Electron Paramagnetic Resonance (RPE) of the impurities Cr3+, Er3+ and Mn3+ in Ca3Ga2Ge3O12 single crystals (Known as CGGG) at frequencies of 1.3, 10 and 34 GHz in the temperatures range 4,2K to 300K. Spin Hamiltonian for the Cr3+ íons, located at octahedric position with symetry Cr3i is given by: H = β[g⊥ (HxSx + HySy) + g‌HzSz] + D (S2z - 1/3 S (S+1). The relevant parameters for CGGG lightly dopped with Cr3+ as determined from the EPR spectra are: g‌ = 1,9662 ± 0,0003, g⊥ = 1,9617 ± 0,0008 and D = 15,82 ± 0,02GHz. CGGG crystals simultaneously dopped with Er3+ and Cr3+ shown the following parameters: g‌ = 1,9662 ± 0,0003, g⊥ = 1,9617 ± 0,0008 e D = 15,82 ± 0,02GHz. Effective spin Hamiltonian parameters for Er3+ íon, located at dodecahedric position and with symetry D2, are: gx = 2,690 ± 0,0005, gy = 4,095 ± 0,005 e gz = 5,082 ± 0,005. Paramagnetic centers Mn2+ produced in Cr3+ dopped crystals, X-ray irradiated, at room temperature, shown the isotropic g-factor g = 2,0066 ± 0,0001 and the hyperfine interaction constant A = 90 Gauss. Also, was measured the temperature dependence of the line width in the three frequency bands, in the range of liquid nitrogen to room temperature. In the case of the X-band, the measurements were extended to lower temperatures, 4.2K to 300K
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Schüle, Georg. "Mechanismen und On-line Dosimetrie bei selektiver RPE Therapie /." Berlin : Dissertation.de, 2003. http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&doc_number=010295155&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA.

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Santana, Ricardo Costa de. "RPE do ion Fe3+ em monocristais e fibras de LiNbO3." Universidade de São Paulo, 1994. http://www.teses.usp.br/teses/disponiveis/76/76132/tde-09042008-084147/.

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O objetivo deste trabalho foi o estudo do íon Fe3+ em monocristais e fibras monocristalinas de LiNbO3, através da técnica espectroscópica da Ressonância Paramagnética Eletrônica (RPE), nas freqüências de 10 e 34GHz, à temperatura ambiente. O Hamiltoniano de Spin para o íon Fe3+ ocupando um sítio de simetria trigonal (C3v) é dado por: H = \'beta\' \'VET.H\' \'VET.g\' \'VET.S\' + \'B20O20+B40O40 . Foram analisadas três amostras de LiNbO3, com diferentes concentrações de Fe3+ e os parâmetros de campo cristalino e fator-g encontrados são: fibra (0.3 mol% de Fe3+) g = 1.9908 \'+OU-\' 0.0002, \'B. SUP. 0 INF. 2\' = 5.4\'+OU-\'0.2x10-2 cm-1 , \'B. SUP. 0 INF. 4\' = -7.7\'+OU-\'1.5x10-5cm-1, monocristal 90 (0.22 mol%) g = 2.0043\'+OU-\'0.0002, \'B. SUP. 0 INF. 2\' = 5.35\'+OU-\'0.25x10-2 cm-1, \'B. SUP. 0 INF. 4\'= - 4.03\'+OU-\'1.4x10-5cm-1, monocristal 99 (0.02 mol%) g = 2.0026\'+OU-\'0.0004, \'B. SUP. 0 INF. 2\' = 5.4\'+OU-\'0.3x10-2 cm-1, \'B. SUP. 0 INF. 4\' = - 8.33\'+OU-\'1.6x10-5cm-1. Foi medida e analisada a dependência angular da largura das linhas nas duas bandas de freqüências. Através de modelos teóricos (Watanabe, Orbach-Das-Sharma, Spinspin, Spin-spin Spin-órbita) calculamos o parâmetro de desdobramento a campo zero, \'B. SUP. 0 INF. 2\', do estado fundamental do íon Fe3+, para determinar qual o sítio que este íon ocupa no LiNbO3.
We report EPR measurements of Fe3+ ion in bulk LiNbO3 single crystals and in the form of fibers. Spin Hamiltonian for the Fe3+ ion in a trigonal symmetry (C3v) site is given by: H = \'beta\' \'VET.H\' \'VET.g\' \'VET.S\' + \'B20O20+B40O40. Measurements were performed at room temperature and two frequency bands, 10 and 34GHz, using three samples of LiNbO3 with different concentrations of Fe3+ g-factor and the crystal field parameters were found to be: for fiber (0.3 mol% of Fe3+) g = 1.9908 \'+OU-\' 0.0002, \'B. SUP. 0 INF. 2\' = 5.4\'+OU-\'0.2x10-2 cm-1 , \'B. SUP. 0 INF. 4\' = -7.7\'+OU-\'1.5x10-5cm-1, for the single crystal 90 (0.22 mol%) g = 2.0043\'+OU-\'0.0002, \'B. SUP. 0 INF. 2\' = 5.35\'+OU \'0.25x10-2 cm-1, \'B. SUP. 0 INF. 4\'= - 4.03\'+OU-\'1.4x10-5 cm-1, and for the single crystal 99 (0.02 mol%) g = 2.0026\'+OU-\'0.0004, \'B. SUP. 0 INF. 2\' = 5.4\'+OU-\'0.3x10-2 cm-1, \'B. SUP. 0 INF. 4\' = - 8.33\'+OU-\'1.6x10-5cm-1. The angular dependence of the line width were also measured and compared with theoretical model. To determine the substitutional site of Fe3+ ion in the LiNbO3 lattice, we calculated the zero field splitting parameter \'B. SUP. 0 INF. 2\' of the ground state, using many theoretical models (Watanabe, Orbach-Das-Sharma, Spin-spin, Spin-Spin Spinorbita).
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Books on the topic "RPE"

1

Moszczynska, Anna. Adhesion, growth and differention of RPE-J cell line. Ottawa: National Library of Canada, 1994.

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Great Britain. Health and Safety Executive., ed. Respiratory protective equipment (RPE): Legislative requirements and lists of HSE-approved standards and type approved equipment. 2nd ed. London: H.M.S.O., 1991.

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Great Britain. Health and Safety Executive., ed. Respiratory protective equipment (RPE): Legislative requirements and lists of HSE approved standards and type approved equipment. London: H.M.S.O., 1990.

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Rope, rape, and faggot: Re-signifying lynching's memory. Duisburg: WiKu, 2009.

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Williams, Glanville. "Rape is rape". Sevenoaks: Butterworths, 1992.

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Publications, Rusting. Dealing with campus rape: Stranger rape, date rape, gang rape. Port Washington, N.Y: Rusting Publications, 2001.

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Shelly, Gary B. RPG II, RPG III, and RPG/400. Boston, MA: Boyd & Fraser, 1990.

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Shelly, Gary B. RPG II, RPG III and RPG/400. Boston, Mass: Boyd & Fraser, 1990.

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Commission, Ireland Law Reform. Rape. Dublin, Ireland: The Commission, 1987.

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Horvath, Miranda A. H., and Jennifer M. Brown. Rape. 2nd ed. London: Routledge, 2022. http://dx.doi.org/10.4324/9781003163800.

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Book chapters on the topic "RPE"

1

Dithmar, Stefan, and Nil Celik. "RPE Autofluorescence." In Retinal Pigment Epithelium in Health and Disease, 233–45. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-28384-1_13.

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Müller, Claudia, and Silvia C. Finnemann. "RPE Phagocytosis." In Retinal Pigment Epithelium in Health and Disease, 47–63. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-28384-1_3.

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Dithmar, Stefan, and Nil Celik. "RPE-Autofluoreszenz." In Das Retinale Pigmentepithel – Physiologie und Pathologie, 259–72. Cham: Springer International Publishing, 2024. http://dx.doi.org/10.1007/978-3-031-35055-9_13.

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Müller, Claudia, and Silvia C. Finnemann. "RPE-Phagozytose." In Das Retinale Pigmentepithel – Physiologie und Pathologie, 51–69. Cham: Springer International Publishing, 2024. http://dx.doi.org/10.1007/978-3-031-35055-9_3.

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Finnemann, Silvia C., and Yongen Chang. "Photoreceptor—RPE Interactions." In Visual Transduction and Non-Visual Light Perception, 67–86. Totowa, NJ: Humana Press, 2008. http://dx.doi.org/10.1007/978-1-59745-374-5_4.

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von der Burchard, Claus, and Johann Roider. "RPE and Laser." In Retinal Pigment Epithelium in Health and Disease, 281–92. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-28384-1_16.

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von der Burchard, Claus, and Johann Roider. "RPE und Laser." In Das Retinale Pigmentepithel – Physiologie und Pathologie, 309–21. Cham: Springer International Publishing, 2024. http://dx.doi.org/10.1007/978-3-031-35055-9_16.

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Stieger, Knut, and Birgit Lorenz. "RPE und Gentherapie." In Das Retinale Pigmentepithel – Physiologie und Pathologie, 291–307. Cham: Springer International Publishing, 2024. http://dx.doi.org/10.1007/978-3-031-35055-9_15.

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Skottman, Heli. "RPE und Stammzelltherapie." In Das Retinale Pigmentepithel – Physiologie und Pathologie, 275–90. Cham: Springer International Publishing, 2024. http://dx.doi.org/10.1007/978-3-031-35055-9_14.

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Szalai, Eszter, John M. Nickerson, and Hans E. Grossniklaus. "RPE Histopathology and Morphometry." In Retinal Pigment Epithelium in Health and Disease, 3–17. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-28384-1_1.

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Conference papers on the topic "RPE"

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Palanker, D., T. Chalberg, A. Vankov, P. Huie, F. E. Molnar, A. Butterwick, M. Calos, M. Marmor, and M. S. Blumenkranz. "Plasma-mediated transfection of RPE." In Biomedical Optics 2006, edited by Fabrice Manns, Per G. Söderberg, and Arthur Ho. SPIE, 2006. http://dx.doi.org/10.1117/12.649624.

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Delori, François C. "Fluorophotometer for Noninvasive Measurement of RPE Lipofuscin." In Noninvasive Assessment of the Visual System. Washington, D.C.: Optica Publishing Group, 1992. http://dx.doi.org/10.1364/navs.1992.tuc3.

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Lipofuscin is a fluorescent pigment that accumulates throughout life preferentially in the macular RPE. At old age, lipofuscin is the major constituent of the cell as it occupies most of the free cytoplasmic [1]. It has been hypothesized that cell congestion by lipofuscin affects the normal metabolic activity of the RPE [1-3], and that this process plays a role in the pathogenesis of age-related macular degeneration (AMD). Massively engorged RPE cells are found adjacent to areas where the RPE is absent secondary to atrophy in AMD [3]. Although the evidence for lipofuscin involvement in AMD is circumstantial, the possibility of quantifying lipofuscin concentration in old subjects and in patients with AMD offers the potential of a meaningful clinical evaluation of the role of lipofuscin in the development of degenerative diseases such as AMD.
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Schuele, Georg, Hanno Elsner, Hans Hoerauf, Carsten Framme, Johann Roider, Reginald Birngruber, and Ralf Brinkmann. "Optoacoustic online dosimetry during selective RPE treatment." In Biomedical Optics 2004, edited by Fabrice Manns, Per G. Soderberg, and Arthur Ho. SPIE, 2004. http://dx.doi.org/10.1117/12.529384.

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Liu, Zhuolin, Kazuhiro Kurokawa, Furu Zhang, and Donald T. Miller. "Characterizing motility dynamics in human RPE cells." In SPIE BiOS, edited by Fabrice Manns, Per G. Söderberg, and Arthur Ho. SPIE, 2017. http://dx.doi.org/10.1117/12.2256144.

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Schüle, Georg, Elke Joachimmeyer, Carsten Framme, Johann Roider, Reginald Birngruber, and Ralf Brinkmann. "Optoacoustic detection of selective RPE cell damage during µs-laser irradiation." In European Conference on Biomedical Optics. Washington, D.C.: Optica Publishing Group, 2001. http://dx.doi.org/10.1364/ecbo.2001.4433_92.

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Objective: The selective damage of the retinal pigment epithelium (RPE) with repetitive µs laser pulses is a new technique for the treatment of several retinal diseases. RPE can selectively be damaged by simultaneously sparing off the adjacent photoreceptor tissue. Objective of this study is to investigate whether optoacoustic (OA) transients occurring during irradiation might be used to control the invisible treatment effect. Setup: A train of frequency doubled Nd:YLF laser pulses (527 nm, 1.7µs pulse length, 500Hz rep. rate) were applied via a laser slit lamp on porcine RPE samples. The acoustic transients were recorded with a broadband transducer. Results: At low radiant exposures (< 100 mJ/cm2) we found a bipolar pressure transient due to thermoelastic expansion of the RPE. The pressure waves from the individual pulses of one pulse train show nearly identical transients. The transients differ slightly from different sites on the sample. At higher radiant exposures (> 150 mJ/cm2), the OA transients differ from pulse to pulse within a pulse train, which can be attributed to microbubble formation around the strong absorbing melanosomes inside the RPE cells. FFT spectra of the OA transients show slight differences in the frequency spectrum with the different radiant exposures.
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Langrock, C., M. M. Fejer, I. Hartl, and M. E. Fermann. "Octave-level spectral broadening in RPE PPLN waveguides." In CLEO 2007. IEEE, 2007. http://dx.doi.org/10.1109/cleo.2007.4453030.

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Hongxing, Yuan, Wu Shaoqun, and Zha Changjun. "Simplified RPE Algorithm and its Fixed-Point Implementation." In 2011 International Conference on Intelligent Computation Technology and Automation (ICICTA). IEEE, 2011. http://dx.doi.org/10.1109/icicta.2011.460.

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Eisner, Ann E., Stephen A. Burns, George W. Hughes, and Robert H. Webb. "Evaluating the Photoreceptor/RPE Complex with an SLO." In Noninvasive Assessment of the Visual System. Washington, D.C.: Optica Publishing Group, 1990. http://dx.doi.org/10.1364/navs.1990.mb4.

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New technology has allowed us to realize the potential of imaging reflectometry in the fundus, as well as better understand the optical factors contributing to measurements. We are mapping photopigment density of human retinas to investigate photoreceptor/retinal epithelial function. We compare maps obtained from reflectometry with results from psychophysical techniques that measure photopigment optical density and visual function. These comparisons can be made across retinal eccentricity and retinal illuminance in the same observer.
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Cao, Z., J. Q. Deng, and K. Liu. "Numerical Research of Multi-Scale Coupling Simulation on Rotary Pressure Exchanger and Pipe System." In ASME 2015 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2015. http://dx.doi.org/10.1115/detc2015-48017.

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Rotary Pressure exchanger (RPE) is an efficient device which recovers pressure energy from liquid streams in process industries. In this work, a multi-scale numerical investigation of pressure propagation in RPE and the pipeline is carried out. A system model including pipe system and RPE component is firstly presented, and is then solved by the integration of 1-D Method of characteristics (MOC) and CFD method. The simultaneous data exchange between the pipeline and RPE is enabled by making use of the existing programming interfaces. At last, the mutual effect of wave phenomenon in pipeline and RPE is evaluated by the synchronous interaction under transient operating conditions. The proposed multi-scale coupling approach in this work could either provide the internal flow details in RPE device or the dynamic behavior of the system, making the numerical simulation more reasonable with system-level accuracy and time-saving.
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Timmermann, Janko, Wilko Heuten, and Susanne Boll. "Input Methods for the Borg-RPE-Scale on Smartwatches." In 9th International Conference on Pervasive Computing Technologies for Healthcare. ICST, 2015. http://dx.doi.org/10.4108/icst.pervasivehealth.2015.259220.

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Reports on the topic "RPE"

1

Rebelo, André, João R. Pereira, Diogo V. Martinho, and João Valente-dos-Santos. Rating of Perceived Exertion in Professional Volleyball: A Systematic Review. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, August 2022. http://dx.doi.org/10.37766/inplasy2022.8.0034.

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Review question / Objective: The purpose of the current review was to systematically and critically evaluate the use RPE-based methods in professional volleyball. Condition being studied: Monitoring athlete load is better understood through sub-dividing load into two groups – internal and external. Internal training load (ITL) refers to the physiological stress that a training session induces in the athlete. Rating of perceived exertion (RPE) has become the most common method of monitoring ITL. The RPE method was originally developed by Borg, and Foster et al. created a simple technique to quantify ITL using a modification of this scale. This technique is known as the session RPE (sRPE) and is derived by multiplying the overall RPE obtained at the end of a training session (or match), using the Borg Category-Ratio 10 scale (BORG-CR10) by the total duration (in minutes) of the training session, to provide a modified training impulse (TRIMP) score.
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Lin, Charles P. Mechanism of Ultrashort Pulse Laser Injury to the RPE (Retinal Pigment Epithelium). Fort Belvoir, VA: Defense Technical Information Center, February 2003. http://dx.doi.org/10.21236/ada417926.

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Lin, Charles P. Study of Short-Pulsed Laser Retinal Injury Mechanisms By Time-Resolved Imaging of Photomechanical Transients in RPE. Fort Belvoir, VA: Defense Technical Information Center, May 2000. http://dx.doi.org/10.21236/ada379774.

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Kruger, Albert. RPP-WTP LAW PILOT MELTER DISASSEMBLY REPORT REP-PLT-026 REV 0. Office of Scientific and Technical Information (OSTI), December 2022. http://dx.doi.org/10.2172/1906870.

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Gupta, Mukesh, Belinda Niemi, and Ingle Paik. RPP-PRT-58489, Revision 1, One Systems Consistent Safety Analysis Methodologies Report. 24590-WTP-RPT-MGT-15-014. Office of Scientific and Technical Information (OSTI), September 2015. http://dx.doi.org/10.2172/1379496.

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Robles, M. I., M. Richardson, and P. Thubert. Using RPI Option Type, Routing Header for Source Routes, and IPv6-in-IPv6 Encapsulation in the RPL Data Plane. RFC Editor, April 2021. http://dx.doi.org/10.17487/rfc9008.

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Sochat, V. RSE-Ops. Office of Scientific and Technical Information (OSTI), July 2021. http://dx.doi.org/10.2172/1806426.

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Kern, Kristen, and Tri Tran. RPD Explorer. Office of Scientific and Technical Information (OSTI), April 2022. http://dx.doi.org/10.2172/1863728.

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Alaettinoglu, C., C. Villamizar, and R. Govindan. RPS IANA Issues. RFC Editor, January 2000. http://dx.doi.org/10.17487/rfc2754.

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Palen-Michel, Madison. Rue Saint-Jacques. Ames: Iowa State University, Digital Repository, February 2013. http://dx.doi.org/10.31274/itaa_proceedings-180814-589.

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