Relevant bibliographies by topics / RP-UPLC

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  1. Journal articles
  2. Dissertations / Theses
  3. Conference papers

Academic literature on the topic 'RP-UPLC'

Author: Grafiati
Published: 10 March 2023
Last updated: 26 July 2025

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Journal articles on the topic "RP-UPLC"

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Zhou, Jianwen, Caixia Han, Hui Cao, et al. "Fast identification of wheat 1BL.1RS translocation by reversed-phase ultra-performance liquid chromatography (RP-UPLC)." Crop and Pasture Science 64, no. 9 (2013): 865. http://dx.doi.org/10.1071/cp13246.

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The 1BL.1RS chromosomal translocation in wheat is the result of replacement of the short arm of chromosome 1B of wheat by the short arm of chromosome 1R of rye, which had been widely used as a parental line in worldwide wheat breeding, resulting in a high percentage of wheat cultivars containing this translocation. A fast and reliable approach to identify this translocation is highly desirable in modern wheat breeding. This study compared reversed-phase ultra-performance liquid chromatography (RP-UPLC), acidic polyacrylamide gel electrophoresis (A-PAGE), liquid chromatography coupled to tandem
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Bharani Pandilla, Chitra K, Nalini C N, Ashok P, and Vadivelan R. "Method development and validation of Ifetroban by RP-UPLC." International Journal of Research in Pharmaceutical Sciences 11, no. 3 (2020): 3158–63. http://dx.doi.org/10.26452/ijrps.v11i3.2429.

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The purpose of this work is to develop and validate reverse phase Ultra performance liquid chromatography (UPLC) method for the rapid and precise determination of ifetroban sodium in its pure form and in formulations. A simple, specific, accurate, precise isocratic UPLC method for analysis of Ifetroban sodium was developed and validated using a Phenomenex C18 column (50 mm x 3.0 mm, 3µ) as the stationary phase, in conjunction using Triethyl amine buffer: methanol in the proportion of 25:75 with a flow rate of 1.0 mL/min, run time is 3 min and UV detector is used at 235 nm wavelength. The devel
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Takale, Nilesh, Neelakandan Kaliyaperumal, Gopalakrishnan Mannathusamy, and Rajarajan Govindasamy. "Method Development and Validation for Quantitative Analysis of Anti-Histamine Promethazine Hydrochloride by RP-UPLC." Oriental Journal Of Chemistry 37, no. 1 (2021): 33–39. http://dx.doi.org/10.13005/ojc/370103.

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The quantitative analysis method for the quantitative analysis of the anti-histaminic drug Promethazine Hydrochloride (PMZ•HCl) is stated by a straightforward, smooth, reliable and reverse step of the ultra-performing liquid chromatographic method (RP-UPLC). Following ICH quidelinesQ2(R1), the RP-UPLC method has been developed and checked. The uniform solution of 3.4% KH2PO4 solution in water, 7.0 pH with dilute KOH, ACN, andMeOH in ratio of 40:40:20, used as a mobile phase. The flow of 0.6 mL/minusing photo diode array detector / UV detector by with wavelength of 254 nm and runtime 3 min. Thi
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Vishnuvardhan, Chiguru, R. Srinivas, and N. Satheeshkumar. "Development and validation of a UPLC method for screening potentially counterfeit anti-hypertensive drugs using design of experiment." Anal. Methods 6, no. 13 (2014): 4610–16. http://dx.doi.org/10.1039/c4ay00384e.

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Nikhil, S. Virkar* M.S. Rode V. S. Pawar S. S. Kadam. "ANALYTICAL METHODOLOGIES FOR DETERMINATION OF TAMSULOSIN HCL AND TOLTERODINE TARTRATE IN BULK AND PHARMACEUTICAL DOSAGE FORM." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES o6, no. 07 (2019): 13791–99. https://doi.org/10.5281/zenodo.3352350.

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<em>Tolterodine tartrate is an antimuscarnic or anticholinergic agent, It works by blocking a chemical that causes contraction of the bladder, It helps to reduce leaking of urine. This medication belongs to the class of drug known as antispasmodic. Tamsulosin HCL approximately 70% of the alpha-1-receptors in human prostate are of the alpha-1A subtype blockage of these receptors causes relaxation of smooth muscles in the bladder neck and prostate. The most commonly adopted methods for determination both drugs are HPLC (High Performance Liquid Chromatography), HPTLC (High Performance Thin Layer
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Dubey, Somshankar, and Mahesh Duggirala. "SIMULTANEOUS ESTIMATION OF LAMIVUDINE, ABACAVIR AND DOLUTEGRAVIR BY UPLC METHOD." International Journal of Applied Pharmaceutics 10, no. 1 (2018): 46. http://dx.doi.org/10.22159/ijap.2018v10i1.21156.

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Objective: To develop a simple, rapid, sensitive and effective reverse phase ultra-performance liquid chromatographic method (RP-UPLC) for simultaneous quantification of lamivudine, abacavir and dolutegravir in pure and tablet dosage forms.Methods: Chromatographic separation was performed by using Waters-ACQUITY UPLC system equipped with auto sampler, photodiode array (PDA) detector, zodiac sil RP C18 (4.6 mm × 250 mm, 3.0 µm) column, phosphate buffer (pH 3.0) and methanol in the ratio of 30:70 %v/v have been delivered at a flow rate of 0.25 ml/min and the detection was carried out using a Ult
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Lakshmi, D. Sri, Jane T. Jacob, D. Srinivasa Sastry, and D. Satyanarayana. "Simultaneous Estimation of Metformin Glimeperide and Voglibose by RP-UPLC." Asian Journal of Pharmaceutical Analysis 7, no. 1 (2017): 23. http://dx.doi.org/10.5958/2231-5675.2017.00005.9.

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Kumar, Kakumani Kishore, Chimalakonda Kameswara Rao, Maddala Vijaya Lakshmi, and Khagga Mukkanti. "A Validated Stability Indicating RP-UPLC Method for Atrovastain Calcium." American Journal of Analytical Chemistry 03, no. 05 (2012): 392–99. http://dx.doi.org/10.4236/ajac.2012.35052.

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Suryawanshi, Shivraj Vithal, Omprakash G. Bhusnure, S. M. Vijayendra Swamy, Sachin B. Gholve, Padmaja S. Girm, and Mahesh J. Birajdar. "Development and Validation of a RP-UPLC Method for Determination of Linezolid in Pharmaceutical Formulation." Journal of Drug Delivery and Therapeutics 9, no. 3-s (2019): 654–58. http://dx.doi.org/10.22270/jddt.v9i3-s.3072.

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A simple, sensitive and accurate RP-UPLC method has been developed for the determination of Linezolid in Tablet formulation. The mix of the Linezolid was found to be 251nm in Acetonitrile: Buffer [40:60(v/v)]. The method shows high sensitivity with linearity 5 to 30μg/ml (regression r2 = 0.999). This method was tested and validated for various parameters according to ICH guidelines and USP. The Detection limit and quantitation limit were found to be 50mg ml–1 and 150 mg ml–1 in Acetonitrile: Buffer [40:60(v/v)] respectively. The results demonstrated that the procedure is accurate, precise and
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Rani, J. David Blessing, and C. Asha Deepti. "STABILITY INDICATING METHOD DEVELOPMENT OF RPUPLC, VALIDATION OF SIMULTANEOUS QUANTITATION OF BUPIVACAINE and MELOXICAM IN PURE AND FORMULATION." RASAYAN Journal of Chemistry 16, no. 03 (2023): 1359–68. http://dx.doi.org/10.31788/rjc.2023.1638409.

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An easy, accurate, and precise RP-UPLC was established and also validated for simultaneous quantitation of Bupivacaine and Meloxicam in the formulation as well as in pure form. An acceptable separation of Bupivacaine and Meloxicam was shown by the developed technique Bupivacaine and Meloxicam retention times were 1.359 min. and 3.687 min. correspondingly. From regression equations, LOQ and LOD were obtained and observed to be 0.2ppm and 0.6ppm - Bupivacaine, 0.06 and 0.0 I 8ppm - Meloxicam, respectively. Stability studies of the injectable dosage form under forced degradation conditions of aci
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Dissertations / Theses on the topic "RP-UPLC"

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Saviano, Alessandro Morais. "Métodos espectrofotométrico, RP-UPLC e microbiológico para determinação de linezolida em formas farmacêuticas." Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/9/9139/tde-26102015-094146/.

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A linezolida é um antibiótico oxazolidinona efetivo contra bactérias patogênicas gram-positivas, incluindo Staphylococcus aureus resistente a meticilina (MRSA), Staphylococcus aureus resistente a glicopeptídeos (GISA) e enterococci resistente a vancomicina (VRE). As oxazolidinonas inibem a translação bacteriana na fase de iniciação da síntese de proteínas, enquanto que a síntese de RNA e DNA não são afetadas. Diversos métodos por cromatografia líquida de alta-eficiência (HPLC) têm sido relatados para a determinação da concentração de linezolida em plasma humano, soro e urina. Entretanto, um nú
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Ida, Björs. "Development of separation method for analysis of oligonucleotides using LC-UV/MS." Thesis, Uppsala universitet, Analytisk farmaceutisk kemi, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-403381.

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Introduction Oligonucleotides are short nucleic acid chains, usually 19-27mer long. They bind to their corresponding chain, making a specific inhibition possible. In pharmaceuticals, this can be used to inhibit the expression of a gene or protein of interest. Oligonucleotides are usually analyzed based on separation using both hydrophobic and ion-exchange properties. In this project, the possibility to use a mixed-mode column to separate these oligonucleotides and their impurities were explored. Method Liquid chromatography is used as the separation method and the method of detection is both m
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Luca, Nompari. "Designing Quality: Quality by Design in the analytical pharmaceutical development." Doctoral thesis, 2018. http://hdl.handle.net/2158/1116278.

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The present thesis study describes an integrated approach for the implementation of Quality by Design principles to screening and development of analytical methods applied to vaccines physical-chemical testing, according to Analytical QbD (AQbD) published in literature. The research study is focused on application of the risk assessment and the experimental design tools to be used to build knowledge about the analytical methods performance and to mitigate the risks of failure. Risk management tools and mathematical/statistical models have been applied to study and define well characterized an
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Conference papers on the topic "RP-UPLC"

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Reinoso, Zain Sanchez, Jacinthe Thibodeau, Laila Ben Said, Ismail Fliss, Laurent Bazinet, and Sergey Mikhaylin. "Bioactive Peptide Production from Slaughterhouse Blood Proteins: Impact of Pulsed Electric Fields and Ph on Enzyme Inactivation, Antimicrobial and Antioxidant Activities of Peptic Hydrolysates from Bovine and Porcine Hemoglobins." In 2022 AOCS Annual Meeting & Expo. American Oil Chemists' Society (AOCS), 2022. http://dx.doi.org/10.21748/fsht2150.

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Slaughterhouse blood is a valuable by-product since multiple bioactive compounds can be derived out of it. Its solid fraction consists mainly of hemoglobin, which is a good source of antimicrobial and antioxidant peptides that can be released by peptic hydrolysis. Nevertheless, this method has limitations such as low yield, expensive cost of enzyme process, and non-eco-friendly production (high energy consumption and chemical reagents requested). Amount the alternative green technologies for protein valorization, pulsed electric field (PEF) stands out since it allows modifying the physicochemi
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