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Academic literature on the topic 'Robinson, D. W. B'

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Published: 10 December 2022
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Journal articles on the topic "Robinson, D. W. B"

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Miller, Jeffrey, Frank Cichocki, Jianfang Ning, Ryan Bjordahl, Zachary Davis, Katie Tuininga, Hongbo Wang, et al. "155 iPSC-derived NK cells mediate robust anti-tumor activity against glioblastoma." Journal for ImmunoTherapy of Cancer 8, Suppl 3 (November 2020): A169. http://dx.doi.org/10.1136/jitc-2020-sitc2020.0155.

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BackgroundGliomas represent the most common brain tumors within the central nervous system, with glioblastoma being the most aggressive type.1 Conventional treatment combines several approaches including surgery, chemotherapy, and radiation.2 However, the prognosis for glioblastoma remains unfavorable, with only 5% of patients surviving more than 5 years post-diagnosis.3 Thus, new treatment approaches are urgently needed. Natural killer (NK) cells directly lyse malignantly transformed or virally infected cells and secrete inflammatory cytokines that polarize cytotoxic immunity. Allogeneic NK cell adoptive transfer has shown clinical benefit in patients with advanced cancer.4–7 However, limitations of this approach include relatively low numbers of donor NK cells that can be isolated during an apheresis and variability in the quality of NK cells between donors. To overcome these limitations, we have developed a GMP manufacturing strategy to mass produce NK cells from induced pluripotent stem cells (iPSCs) as an approach to off-the-shelf cancer immunotherapy. We refer to these cells as ‘iNK’ (iPSC-derived NK) cells. Here, we provide preclinical data demonstrating the efficacy of iNK cells for immunotherapy against glioblastoma.Abstract 155 Figure 1Engineered iNK cells exhibit highly effective antitumor function in a xenogeneic model of glioblastoma. (A) Schematic of the experimental design to test iNK cell function against glioblastoma in vivo. (B) Kaplan Meier plots showing survival for groups of mice that received either vehicle alone or iNK cells after tumor engraftment (n=5 mice/group)MethodsWe generated iNK cells using previously published methods.8–10 iNK cells were used as effectors against an array of patient-derived glioblastoma lines in 2-dimensional live imaging IncuCyte assays where iNK cell-mediated killing was observed over the course of 48 hours. To investigate iNK cell infiltration and cytotoxicity in a more physiological context that accounts for the 3-dimensional architecture of the tumor, we also performed live imaging IncuCyte assays using iNK cells as effectors against glioblastoma spheroids. To test the anti-tumor function of iNK cells in vivo, we implanted patient-derived glioblastoma cells into mice via intracranial injection. Seven days later, 5 mice received intratumoral injections of iNK cells, and 5 mice received vehicle alone (as a control; figure 1A). All mice were monitored for weight and survival over 100 days.Results iNK cells exhibited strong and sustained cytotoxicity against 6 primary patient-derived mesenchymal glioblastoma lines in 2-dimensional IncuCyte assays and complete infiltration and destruction of glioblastoma spheroids in 3-dimensional IncuCyte assays. In xenogeneic adoptive transfer experiments, all mice receiving intratumoral injections of iNK cells survived out to day 100, while all mice in the vehicle group became moribund and had to be sacrificed by day 60 (figure 1B).ConclusionsiNK cells are highly cytotoxic against glioblastoma cells, and our preclinical in vivo data provides proof-of-concept for future clinical trials.Ethics ApprovalThis project has been approved by the University of Minnesota IACUC. Approval ID: 1812-36595AReferencesLouis D N, Perry A, Reifenberger G, von Deimling A, Figarella-Branger D, Cavenee W K, Ohgaki H, Wiestler O D, Kleihues P, Ellison D W. The 2016 world health organization classification of tumors of the central nervous system: a summary. Acta Neuropathol 2016;131:803–820.Stupp R, Mason W P, van den Bent M J, Weller M, Fisher B, Taphoorn M J B, Belanger K, Brandes A A, Marosi C, Bogdahn U, Curschmann J, Janzer R C, Ludwin S K, Gorlia T, Allgeier A, Lacombe D, Cairncross J G, Eisenhauer E, Mirimanoff R O, European Organization for Research and Treatment of Cancer Brain Tumor and Radiotherapy Groups; National Cancer Institute of Canada Clinical Trials Group. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med 2005;352:987–996.Thakkar JP, Dolecek TA, Horbinski C, Ostrom QT, Lightner DD, Barnholz-Sloan JS, Villano JL. Epidemiologic and molecular prognostic review of glioblastoma. Cancer Epidemiol Biomarkers Prev 2017;23:1985–1996.Miller J S, Soignier Y, Panoskaltsis-Mortari A, McNearney S A, Yun G H, Fautsch S K, McKenna D, Le C, Defor T E, Burns L J, Orchard P J, Blazar B R, Wagner J E, Slungaard A, Weisdorf D J, Okazaki J, McGlave P B. Successful adoptive transfer and in vivo expansion of human haploidentical NK cells in patients with cancer. Blood 2005;105:3051–3057.Bachanova V, Cooley S, Defor T E, Verneris M R, Zhang B, McKenna D H, Curtsinger J, Panoskaltsis-Mortari A, Lewis D, Hippen K, McGlave P, Weisdorf D J, Blazar B R, Miller J S. Clearance of acute myeloid leukemia by haploidentical natural killer cells is improved using IL-2 diphtheria toxin fusion protein. Blood 2014;123:3855.Ciurea S O, Schafer J R, Bassett R, Denman C J, Cao K, Willis D, Rondon G, Chen J, Soebbing D, Kaur I, Gulbis A, Ahmed S, Rezvani K, Scpall E J, Lee D A, Champlin R E. Phase 1 clinical trial using mbIL21 ex vivo-expanded donor-derived NK cells after haploidentical transplant. Blood 2017;130:1857–1868.Romee R, Rosario M, Berrien-Elliott M M, Wagner J A, Jewell B A, Schappe T, Leong J W, Abdel-Latif S, Schneider S E, Willey S, Neal C C, Yu L, Oh T, Lee S, Mulder A, Cooper M A, Fehniger T A. Cytokine-induced memory-like natural killer cells exhibit enhanced responses against myeloid leukiemia. Sci Transl Med 2016:8;375ra123.Valamehr B, Abujarour R, Robinson M, Le T, Robbins D, Shoemaker D, Flynn P. A novel platform to enable the high-throughput derivation and characterization of feeder-free human iPSCs. Sci Rep 2012:2;213.Valamehr B, Robinson M, Abujarour R, Rezner B, Vranceanu F, Le T, Medcalf A, Lee T T, Fitch M, Robbins D, Flynn P. Platform for induction and maintenance of transgene-free hiPSCs resembling ground state pluripotent stem cells. Stem Cell Reports 2014;2:366–381.Zhu H, Blum R H, Bjordahl R, Gaidarova S, Rogers P, Lee T T, Abujarour R, Bonello G B, Wu J, Tsai P-F, Miller J S, Walcheck B, Valamehr B, Kaufman D S. Pluripotent stem cell-derived NK cells with high-affinity noncleavable CD16a mediate improved antitumor immunity. Blood 2020;135:399–410.
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Patel, Drasti, Hamish Thomas Reid, Lara Rasha, Matilda Fransson, Ludovic Broche, and Paul R. Shearing. "In-Situ/Operando X-Ray CT Characterisation of Lithium-Ion Pouch Cells during Thermal Failure." ECS Meeting Abstracts MA2022-01, no. 2 (July 7, 2022): 349. http://dx.doi.org/10.1149/ma2022-012349mtgabs.

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The safety of concerns of lithium-ion batteries continues to be a prevalent obstacle toward their widespread application from vehicle electrification to space exploration. Aside from the highly oxidising and reducing electrode materials, their safety is compounded by an inherent drawback of poor heat dissipation [1]. High-speed imaging with in-situ/operando X-ray CT has been used extensively to study various lithium-ion battery safety features and failure mechanisms [2][3], including thermal failure [4]. However, these are exclusively using synchrotron X-ray sources which are limited in terms of both access and data recording capabilities: high frame rates require the data collection window to be restricted to a few seconds. During lithium-ion battery failure, there are several changes to a cell structure leading up to thermal runaway (TR) which can take minutes, and as a result are often missed. Here, we present an instrument that simulates thermal failure for lab-based radiography at slower imaging speeds and longer recording lengths, which has been validated by correlative synchrotron measurements. The failure mechanisms within a fully charged (100 % SOC, 4.2 V) commercially available LiCoO2 cathode and graphite anode pouch cell (651628-2C, AA Portable Power Corp) rated at 210 mAh are investigated. Three samples are studied using lab-based radiography at a frame rate of 3.75 fps with a 16.1 µm pixel resolution and, for comparison, an additional three samples are studied using synchrotron X-ray sources at a higher speed of 20,000 fps with a 13.3 µm pixel resolution. For the six samples investigated, the total time taken from a start temperature of 80 °C to TR is approximately 20 minutes and the onset temperatures for TR are recorded within the range of 196 °C to 210 °C. The beginning of the TR event (defined as a sample temperature increase greater than 15 °C s-1), where the effects to the electrode structure are the most catastrophic, lasts for approximately 1 s. Operando radiographic images during this event reveal that the structural displacement of electrode layers begins at the centre of the cell and propagates outwards in a wave-like motion. The electrode displacement, as a result, is quantified by cross-correlating Gabor signals and spatiotemporal mapping [5] in both types of datasets. For the lab-based radiography, data is recorded from the start temperature to TR (lasting approximately 20 minutes), and reactions such as the electrolyte decomposition, ca. 105 °C, and separator melting, ca.130 °C are characterised in the context of electrode deformation and gas evolution. Investigations of pre- and post-failure 3D X-ray CT images further verify the uniformity of the pristine (or pre-failure) cell assembly as well as the estimated post-failure behaviour between samples. Finally, by comparison with correlative synchrotron measurements, the instrument for inducing thermal failure for lab-based X-ray CT is proven to be a viable and more accessible method to investigate thermal failure within a 210 mAh pouch cell. While synchrotron data has a higher-speed imaging advantage, it is limited to only recording the short TR event at a high temporal resolution. Whereas continuous imaging in lab-based radiography has the benefit of measuring the slower architectural changes taking place up to TR, albeit at a marginally lower spatial resolution. References [1] D. H. Doughty and E. P. Roth, Interface Mag., 21, 37–44 (2012). [2] D. P. Finegan, M. Scheel, J. B. Robinson, B. Tjaden, M. Di Michiel, G. Hinds, D. J. L. Brett, and P. R. Shearing, Phys. Chem. Chem. Phys., 18, 30912–30919 (2016). [3] D. P. Finegan, M. Scheel, J. B. Robinson, B. Tjaden, I. Hunt, T. J. Mason, J. Millichamp, M. Di Michiel, G. J. Offer, G. Hinds, D. J. L. Brett, and P. R. Shearing, Nat. Commun., 6, 6924 (2015). [4] M. T. M. Pham, J. J. Darst, D. P. Finegan, J. B. Robinson, T. M. M. Heenan, M. D. R. Kok, F. Iacoviello, R. Owen, W. Q. Walker, O. V. Magdysyuk, T. Connolley, E. Darcy, G. Hinds, D. J. L. Brett, and P. R. Shearing, J. Power Sources, 470, 228039 (2020). [5] A. N. P. Radhakrishnan, M. Buckwell, M. Pham, D. P. Finegan, A. Rack, G. Hinds, D. J. L. Brett, and P. R. Shearing, ChemRxiv (2021).
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Grigoryev, L. M., and V. A. Pavlyushina. "Inter-country inequality as a dynamic process and the problem of post-industrial development." Voprosy Ekonomiki, no. 7 (July 28, 2018): 5–29. http://dx.doi.org/10.32609/0042-8736-2018-7-5-29.

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The phenomenon of economic growth is studied by economists and statisticians in various aspects for a long time. Economic theory is devoted to assessing factors of growth in the tradition of R. Solow, R. Barrow, W. Easterly and others. During the last quarter of the century, however, the institutionalists, namely D. North, D. Wallis, B. Weingast as well as D. Acemoglu and J. Robinson, have shown the complexity of the problem of development on the part of socioeconomic and political institutions. As a result, solving the problem of how economic growth affects inequality between countries has proved extremely difficult. The modern world is very diverse in terms of development level, and the article offers a new approach to the formation of the idea of stylized facts using cluster analysis. The existing statistics allows to estimate on a unified basis the level of GDP production by 174 countries of the world for 1992—2016. The article presents a structured picture of the world: the distribution of countries in seven clusters, different in levels of development. During the period under review, there was a strong per capita GDP growth in PPP in the middle of the distribution, poverty in various countries declined markedly. At the same time, in 1992—2016, the difference increased not only between rich and poor groups of countries, but also between clusters.
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Roberts, R. C. "Genetics of Reproduction in Sheep. By R. B. Land and D. W. Robinson. Sevenoaks, Kent: The Butterworth Group. 1984. £40.00 Hardcover. ISBN 407 00302 9." Genetical Research 46, no. 1 (August 1985): 116–18. http://dx.doi.org/10.1017/s0016672300022539.

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Robinson, David B. "Textual notes on Plato's Sophist." Classical Quarterly 49, no. 1 (May 1999): 139–60. http://dx.doi.org/10.1093/cq/49.1.139.

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In editing Plato's Sophist for the new OCT vol. I, ed. E. A. Duke, W. F. Hicken, W. S. M. Nicoll, D. B. Robinson, and J. C. G. Strachan (Oxford, 1995), there was less chance of giving novel information about W = Vind. Supp. Gr. 7 for this dialogue than for others in the volume, since Apelt's edition of 1897 was used by Burnet in 1900 and was based on Apelt's own collation of W. The result was better than the somewhat confused information printed by Burnet, even in his 1905 reprint, for W for the other dialogues in vol. I. (This seems perhaps to have arisen from some misinterpretation by Burnet of Kral's method of reporting W.) But in the Sophist as elsewhere in vol. I collations largely due to Dr W. S. M. Nicoll added new facts about all of BDTWP and their correctors, and the search for testimonia largely carried out by Dr E. A. Duke added new facts in that area. A reviewer counts 66 changes in our text of the Sophist, which may perhaps be a slight over-estimate. Classification of changes as substantive or as falling into different groups is sometimes difficult, but I think plausible figures are as follows. We (myself aided in the earlier sections by Nicoll) have in 25 places made a different choice of readings from the primary mss. and testimonia. We have printed conjectures where Burnet kept a ms. reading in 17 places, but conversely we have reverted to a ms. reading where Burnet had a conjecture in 8 places. We have printed alternative conjectures to conjectures adopted by Burnet in 6 places. So we have actually departed from the primary sources on at most 9 more occasions overall than Burnet. What must be noted is that Burnet had already printed conjectures (including readings from secondary mss.) on something like 87 occasions (12 from secondary mss., 75 from modern conjectures from Stephanus onwards), so our percentage addition to Burnet's departures from the primary sources is modest. Moreover Burnet printed about 25 readings from testimonia; we have followed him in 20 or so of these cases, and this in turn implies that the primary mss. are in error at these further 20 places. It needs to be underlined that though Burnet undoubtedly deserved to be regarded as a safe and cautious editor, nevertheless he departed from the primary mss. on average about twice per Stephanus page in this dialogue. Sometimes, of course, testimonia showed him right to do this, but testimonia cover only a quite small part of this dialogue. Otherwise Burnet accepted almost 90 conjectures. For the Politicus the figures are fairly similar; Burnet accepted 22 Byzantine conjectures and 35–40 more modern ones. The new OCT there adds 15 or so more (not all new) conjectures. (On the Politicus in the new OCT see Robinson [1995].)
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McLeod, Kenneth J. "Electric Fields in Vertebrate Repair. Natural and Applied Voltages in Vertebrate Regeneration and Healing.Richard B. Borgens , Kenneth R. Robinson , Joseph W. Vanable, Jr. , Michael E. McGinnis , Colin D. McCaig." Quarterly Review of Biology 66, no. 1 (March 1991): 80–81. http://dx.doi.org/10.1086/417072.

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Тарабань, Роман, and Маршал Філіп Х. "Deep Learning and Competition in Psycholinguistic Research." East European Journal of Psycholinguistics 4, no. 2 (December 28, 2017): 67–74. http://dx.doi.org/10.29038/eejpl.2017.4.2.rta.

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MacWhinney, Bates, and colleagues developed the Competition Model in the 1980s as an alternate to Chomskyan models that encapsulate syntax as a special-purpose module. The Competition Model adopted the functional perspective that language serves communicative goals and functions. In contrast to the premise that knowledge of language is innate, the Competition model asserts that language is learned and processed through general cognitive mechanisms that identify and weight phonological, morphological, syntactic, and semantic cues in the language experiences of the learner. These weighted cues guide the language user in the comprehension and production of language forms. The present article provides background on the Competition Model, describes machine simulations of linguistic competition, and extends the principles of the Competition Model to new machine models and applications through deep learning networks. References Bates, E. & MacWhinney, B. (1982). A functionalist approach to grammar. In E. Wanner & L. Gleitman (Eds.), Language acquisition: the state of the art. New York: Cambridge University Press. Bates, E., & MacWhinney, B. (1989). Functionalism and the competition model. In: The Crosslinguistic Study of Sentence Processing, (pp 3-76). B. MacWhinney and E. Bates (Eds.), New York: Cambridge University Press. Devescovi, A., D’Amico, S., Smith, S., Mimica, I., & Bates, E. (1998). The development of sentence comprehension in Italian and Serbo-Croatian: Local versus distributed cues. In: Syntax and Semantics: Vol. 31. Sentence Pocessing: A Cross-Linguistic Perspective, (pp. 345-377). D. Hillert (Ed.), San Diego: Academic Press. Hauser, M. D., Chomsky, N., & Fitch, W. T. (2002). The faculty of language: What it is, who has it, and how did it evolve? Science, 298, 1569-1579. Just, M. A., & Carpenter, P. A. (1980). A theory of reading: From eye fixations to comprehension. Psychological Review, 87, 329-354. Langacker, R. (1989). Foundations of cognitive grammar. Vol. 2: Applications. Stanford: Stanford University Press. Li, P., & MacWhinney, B. (2013). Competition model. In: The Encyclopedia of Applied Linguistics. C. A. Chapelle (Ed.), Malden, MA: Wiley. MacWhinney, B. (1987). The competition model. In: Mechanisms of Language Acquisition, (pp.249-308). B. MacWhinney (Ed.).Hillsdale, NJ: Lawrence Erlbaum. MacWhinney, B. (2001). The competition model: The input, the context, and the brain. In: Cognition and Second Language Instruction, (pp. 69–90). P. Robinson (Ed.), New York: Cambridge University Press. MacWhinney, B. (2008). A Unified Model. In: Handbook of Cognitive Linguistics and Second Language Acquisition, (pp. 341-371). P. Robinson & N. Ellis (Eds.). Mahwah, NJ: Lawrence Erlbaum Associates. MacWhinney B. (2012). The logic of the Unified Model. In: The Routledge Handbook of Second Language Acquisition, (pp. 211–227). S. Gass and A. Mackey (Eds.). New York: Routledge. MacWhinney, B. (2015). Multidimensional SLA. In: Usage-Based Perspectives on Second Language Learning, (pp. 22-45). S. Eskilde and T. Cadierno (Eds.). New York: Oxford University Press. MacWhinney, B., Bates, E. & Kliegl, R. (1984). Cue validity and sentence interpretation in English, German, and Italian. Journal of Verbal Learning and Verbal Behavior, 23, 127-150. MacWhinney, B., Leinbach, J., Taraban, R., & McDonald, J. (1989). Language learning: Cues or rules? Journal of Memory and Language, 28, 255-277. McClelland, J. L., & Rumelhart, D. E. (1986). Parallel Distributed Processing. Explorations in the Microstructure of Cognition. Volume 2: Psychological and Biological Models. Cambridge, MA: MIT Press. Presson, N. & MacWhinney, B. (2011). The Competition Model and language disorders. In: Handbook of Psycholinguistic and Cognitive Processes, (pp. 31-48). J. Guendozi, F. Loncke, and M. Williams (Eds.). New York: Psychology Press. Sokolov, J. L. (1988). Cue validity in Hebrew sentence comprehension. Journal of Child Language, 15, 129-156. Taraban, R. (2004). Drawing learners’ attention to syntactic context aids gender-like category induction. Journal of Memory and Language, 51(2), 202-216. Taraban, R. (2017). Hate, white supremacy, PTSD, and metacognition. In: Improve With Metacognition [online]. L. Scharff, A. Richmond, & J. Draeger (Eds.). Retrieved from: www.improvewithmetacognition.com. Taraban, R., & Kempe, V. (1999). Gender processing in native and non-native Russian speakers. Applied Psycholinguistics, 20, 119-148. Taraban, R., McDonald, J., & MacWhinney, B. (1989). Category learning in a connectionist model: Learning to decline the German definite article. In R. Corrigan, F. Eckman, & M. Noonan (Eds.), Linguistic categorization (pp. 163-193). Philadelphia: Benjamins. Taraban, R., & Roark, B. (1996). Competition in learning language-based categories. Applied Psycholinguistics, 17, 125-148.
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George, Thomas Young, Emily F. Kerr, Naphtal O. Haya, Roy G. Gordon, and Michael J. Aziz. "Size and Charge Effects on Organic Flow Battery Crossover Evaluated By Quinone Permeabilities through Nafion." ECS Meeting Abstracts MA2022-01, no. 3 (July 7, 2022): 486. http://dx.doi.org/10.1149/ma2022-013486mtgabs.

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Organic and metalorganic reactants have become promising for long-lifetime flow batteries. Synthetic chemistry unlocks a wide design space to tailor reactant redox potential, solubility, chemical and electrochemical stability, redox kinetics, and transport properties. Minimizing the crossover of reactants through the membrane or separator is one crucial design goal. To that end, this work contributes a systematic evaluation of size- and charge-based effects on small molecule permeability through Nafion. These results inform the design of flow battery electrolytes that improve the transport selectivity of ion exchange membranes. Some recent flow battery designs have included crossover suppression strategies based on size and charge of reactants. One option is to leverage size-exclusion, for example by tethering redox-active moieties to polymer backbones,1,2 or by oligomerizing redox-active monomers.3-5 A charge-based strategy has been employed to decrease viologen crossover: sulfonate6 or phosphonate7 solubilizing groups were attached to the redox active core and paired with a cation exchange membrane, reducing crossover compared to previous iterations of this chemistry. Crossover rates of some organic-based flow battery molecules have been estimated to be very low, but other considerations must be balanced for designing viable battery technology. For example, electrolyte cost and solubility may be in direct tension with a crossover suppression strategy based on increasing redox mediator size.8 Untangling the effects of different membrane-molecule selectivity mechanisms is a valuable step on the path to advancing redox active molecule design. This work evaluates a set of quinones in which size is varied by the number of aromatic rings (e.g. hydroquinone, anthraquinone) and charge number is varied almost independently through sulfonation. Each sulfonate moiety contributes a -1 charge, increasing the magnitude of the molecule charge number with the same sign as the fixed charges in Nafion. Effective size of solvated species is accessed through rotating disk electrode voltammetry: Stokes radii are calculated from measured diffusion coefficients. We found over an order of magnitude permeability reduction per sulfonate, emphasizing the importance of charge-based exclusion for ion exchange membranes. In comparison, size-exclusion effects are less impactful. For example, the Stokes radius of anthraquinone 2,6-disulfonate (AQDS) is twice that of hydroquinone 2,5-disulfonate but their permeabilities fall within the same order of magnitude. 1. T. Hagemann, J. Winsberg, M. Grube, I. Nischang, T. Janoschka, N. Martin, M. D. Hager, and U. S. Schubert, Journal of Power Sources, 378, 546 (2018). 2. T. Janoschka, N. Martin, U. Martin, C. Friebe, S. Morgenstern, H. Hiller, M. D. Hager, and U. S. Schubert, Nature, 527, 78 (2015). 3. M. J. Baran, M. N. Braten, E. C. Montoto, Z. T. Gossage, L. Ma, E. Chenard, J. S. Moore, J. Rodrıguez-Lopez, and B. A. Helms, Chemistry of Materials, 30, 3861 (2018). 4. K. H. Hendriks, S. G. Robinson, M. N. Braten, C. S. Sevov, B. A. Helms, M. S. Sigman, S. D. Minteer, and M. S. Sanford, ACS Central Science, 4, 189 (2018). 5. S. E. Doris, A. L. Ward, A. Baskin, P. D. Frischmann, N. Gavvalapalli, E. Chenard, C. S. Sevov, D. Prendergast, J. S. Moore, and B. A. Helms, Angewandte Chemie, 129, 1617 (2017). 6. C. Debruler, B. Hu, J. Moss, J. Luo, and T. L. Liu, ACS Energy Letters, 3, 663, (2018). 7. S. Jin, E. M. Fell, L. Vina-Lopez, Y. Jing, P. W. Michalak, R. G. Gordon, and M. J. Aziz, Advanced Energy Materials, 10, (2020). 8. M. L. Perry, J. D. Saraidaridis, and R. M. Darling, Current Opinion in Electrochemistry, 21, 311 (2020).
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Jacquemond, Rémy Richard, Maxime van der Heijden, Emre Burak Boz, Jeffrey A. Kowalski, Katharine Greco, Kitty Nijmeijer, Fikile R. Brushett, Pierre Boillat, and Antoni Forner-Cuenca. "Neutron Radiography As a Powerful Method to Visualize Reactive Flows in Redox Flow Batteries." ECS Meeting Abstracts MA2022-01, no. 48 (July 7, 2022): 2014. http://dx.doi.org/10.1149/ma2022-01482014mtgabs.

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Spatial and temporal gradients in reactant concentration, influenced by local microstructure and surface properties, govern the performance and durability of various advanced electrochemical systems. The cell and stack performance is typically assessed using traditional electrochemical diagnostics (e.g. polarization curves, electrochemical impedance spectroscopy) and the influence of materials is macroscopically evaluated based on empirical comparison of novel materials with the current state-of-the-art. While this is a valid approach to identify promising candidates, valuable information is lost due to the difficulty of identifying performance-limiting factors. Operando imaging of electrochemical systems, in tandem with complementary electrochemical diagnostics, has been instrumental in the development of advanced polymer electrolyte fuel cells1,2 and, more recently, lithium-ion batteries3,4. Over the past few years, several groups have developed novel imaging and spectroscopic techniques for operando characterization of redox flow batteries, which is the focus of this work. Wong et al. employed fluorescence microscopy and particle velocimetry to image concentration and velocity distributions near the electrode-flow field interface5. Tanaka et al. visualized flow distribution in redox flow batteries with infrared thermography6. Zhao et al. employed in-situ nuclear magnetic resonance to track reaction mechanisms occurring within the electrolyte7. Finally, several groups recently employed X-ray tomographic microscopy to visualize gas pockets within the liquid electrolyte imbibed porous electrode8–10. While these methods have provided important insights, an approach that enables quantitative mapping of species concentrations, in a non-invasive fashion and within an operating cell, has remained elusive. In this presentation, I will discuss our recent efforts to develop neutron radiography as an operando characterization method for non-aqueous redox flow batteries. We leverage the high attenuation of organic materials (i.e., high hydrogen content) in solution and, combined with isotopic labelling, we perform subtractive neutron imaging to quantify the concentration of active species and supporting electrolytes. To demonstrate the potential of this diagnostic tool, we characterize active species concentration distribution within a redox flow cell in a single electrolyte configuration with a non-aqueous electrolyte containing a TEMPO/TEMPO+ redox couple and study the influence of electrode microstructure, membrane type (e.g. porous or dense), and flow field design. To resolve the concentration profiles across the different layers, we employ the in-plane imaging configuration11 and correlate these concentration profiles to cell performance via polarization measurements under different operating conditions. In the final part of the talk, I will discuss our latest experimental campaign in which we investigated the use of energy-selective neutron radiography to deconvolute concentrations of active species and supporting electrodes during operation. References 1 P. Boillat, E. H. Lehmann, P. Trtik and M. Cochet, Curr. Opin. Electrochem., , DOI:https://doi.org/10.1016/j.coelec.2017.07.012. 2 J. Eller, T. Rosén, F. Marone, M. Stampanoni, A. Wokaun and F. N. Büchi, J. Electrochem. Soc., 2011, 158, B963. 3 B. Michalak, H. Sommer, D. Mannes, A. Kaestner, T. Brezesinski and J. Janek, Sci. Rep., 2015, 5, 15627. 4 D. P. Finegan, M. Scheel, J. B. Robinson, B. Tjaden, I. Hunt, T. J. Mason, J. Millichamp, M. Di Michiel, G. J. Offer, G. Hinds, D. J. L. Brett and P. R. Shearing, Nat. Commun., 2015, 6, 6924. 5 A. A. Wong, M. J. Aziz and S. Rubinstein, ECS Trans. , 2017, 77, 153–161. 6 H. Tanaka, Y. Miyafuji, J. Fukushima, T. Tayama, T. Sugita, M. Takezawa and T. Muta, J. Energy Storage, 2018, 19, 67–72. 7 E. W. Zhao, T. Liu, E. Jónsson, J. Lee, I. Temprano, R. B. Jethwa, A. Wang, H. Smith, J. Carretero-González, Q. Song and C. P. Grey, Nature, 2020, 579, 224–228. 8 R. Jervis, L. D. Brown, T. P. Neville, J. Millichamp, D. P. Finegan, T. M. M. Heenan, D. J. L. Brett and P. R. Shearing, J. Phys. D. Appl. Phys., , DOI:10.1088/0022-3727/49/43/434002. 9 F. Tariq, J. Rubio-Garcia, V. Yufit, A. Bertei, B. K. Chakrabarti, A. Kucernak and N. Brandon, Sustain. Energy Fuels, 2018, 2, 2068–2080. 10 K. Köble, L. Eifert, N. Bevilacqua, K. F. Fahy, A. Bazylak and R. Zeis, J. Power Sources, , DOI:10.1016/j.jpowsour.2021.229660. 11 P. Boillat, D. Kramer, B. C. Seyfang, G. Frei, E. Lehmann, G. G. Scherer, A. Wokaun, Y. Ichikawa, Y. Tasaki and K. Shinohara, Electrochem. commun., 2008, 10, 546–550.
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Höflmayer, Felix. "NEW RESEARCH ON THONIS-HERACLEION - (D.) Robinson, (F.) Goddio (edd.) Thonis-Heracleion in Context. (Oxford Centre for Maritime Archaeology 8.) Pp. xiv + 319, colour figs, b/w & colour ills, b/w & colour maps. Oxford: Oxford Centre for Maritime Archaeology, School of Archaeology, University of Oxford, 2015. Cased, £45, US$90. ISBN: 978-1-905905-33-1." Classical Review 67, no. 1 (October 20, 2016): 209–11. http://dx.doi.org/10.1017/s0009840x16002109.

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Dissertations / Theses on the topic "Robinson, D. W. B"

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Juretzko, Julia Monika Verfasser], Stephan W. [Akademischer Betreuer] [Gutachter] Vogt, and Andreas B. [Gutachter] [Imhoff. "Langzeitergebnisse nach arthroskopischer Schulterstabilisierung / Julia Monika Juretzko ; Gutachter: Andreas B. Imhoff, Stephan W. Vogt ; Betreuer: Stephan W. Vogt." München : Universitätsbibliothek der TU München, 2017. http://d-nb.info/1135385130/34.

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Vermeeren, Mats [Verfasser], Yuri B. [Akademischer Betreuer] Suris, Yuri B. [Gutachter] Suris, Christian [Gutachter] Lubich, and Frank W. [Gutachter] Nijhoff. "Continuum limits of variational systems / Mats Vermeeren ; Gutachter: Yuri B. Suris, Christian Lubich, Frank W. Nijhoff ; Betreuer: Yuri B. Suris." Berlin : Technische Universität Berlin, 2018. http://d-nb.info/1174251263/34.

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Sadowski, René [Verfasser], Sabine B. [Gutachter] Rau, and Franz W. [Gutachter] Kellermanns. "CEO-Nachfolge in Familienunternehmen / René Sadowski ; Gutachter: Sabine B. Rau, Franz W. Kellermanns." Vallendar : WHU - Otto Beisheim School of Management, 2016. http://d-nb.info/1115721712/34.

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Sadowski, René Verfasser], Sabine B. [Gutachter] Rau, and Franz W. [Gutachter] [Kellermanns. "CEO-Nachfolge in Familienunternehmen / René Sadowski ; Gutachter: Sabine B. Rau, Franz W. Kellermanns." Vallendar : WHU - Otto Beisheim School of Management, 2016. http://d-nb.info/1115721712/34.

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Tretbar, Maik [Verfasser], and Christian B. W. [Akademischer Betreuer] Stark. "Untersuchungen zur Eisenkatalysierten Epoxidierung und C-H-Oxidation / Maik Tretbar. Betreuer: Christian B. W. Stark." Hamburg : Staats- und Universitätsbibliothek Hamburg, 2012. http://d-nb.info/1030365628/34.

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Heldt, Christian [Verfasser], A. [Gutachter] Radbruch, B. [Gutachter] Müller, and W. [Gutachter] Lockau. "Differentielle Expression von HLA-DRB-Genen / Christian Heldt ; Gutachter: A. Radbruch, B. Müller, W. Lockau." Berlin : Humboldt-Universität zu Berlin, 2002. http://d-nb.info/1207636444/34.

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MARQUES, MARIANA RIBEIRO. "AFFECTION AND SENSORIALITY IN THE THEORIES OF B. ESPINOSA, S. FREUD AND D. W. WINNICOTT." PONTIFÍCIA UNIVERSIDADE CATÓLICA DO RIO DE JANEIRO, 2012. http://www.maxwell.vrac.puc-rio.br/Busca_etds.php?strSecao=resultado&nrSeq=20706@1.

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PONTIFÍCIA UNIVERSIDADE CATÓLICA DO RIO DE JANEIRO
COORDENAÇÃO DE APERFEIÇOAMENTO DO PESSOAL DE ENSINO SUPERIOR
PROGRAMA DE SUPORTE À PÓS-GRADUAÇÃO DE INSTS. DE ENSINO
Este trabalho se propõe a realizar uma cartografia dos elementos indicadores de uma teoria dos afetos nas obras de B. Espinosa, S. Freud e D. W. Winnicott no âmbito dos processos de subjetivação que descrevem. As relações entre corpo e mente, afeto e representação, assim como a participação da sensorialidade nos processos de constituição subjetiva são alguns dos temas recorrentes em cada um dos autores tratados. Partimos da filosofia prática de Espinosa, em que os afetos são a mola propulsora para o conhecimento e para a expansão de potência. Em seguida, expomos o pensamento de Freud, que tem como base o estudo do conceito de pulsão e o entendimento do afeto como um representante psíquico desta. Por fim, passamos ao estudo da teoria de Winnicott, na qual a experiência sensível é imprescindível aos processos de desenvolvimento emocional. Percorremos as linhas gerais do pensamento desses autores sobre o tema dos afetos e da sensorialidade com o intuito de pensar uma clínica psicanalítica conectada à experiência sensível. Traçamos algumas interlocuções possíveis, assim como apontamos algumas diferenças entre os autores, considerando os diferentes contextos teóricos do qual fazem parte.
This work intends to conduct a cartography of the indicators of a theory of affects in the works of B. Spinoza, S. Freud and D. W. Winnicott in the subjectivation processes they describe. The relationships between body and mind, affection and representation, as well as the participation of the sensoriality in the processes of subjective constitution are some of the recurring themes in each of the authors treated. We start from the practical philosophy of Spinoza, in which the affections are the driving force for knowledge and for the expansion of power. Then we expose Freud s thinking, which is based on the study of the concept of drive and on the understanding of affect as psychic representative of the drive. Finally, we come to the study of Winnicott s theory, in which sensory experience is essential to the processes of emotional development. We go through the general lines of thought of these authors on the subject of affection and sensoriality with the aim of a psychoanalytic thinking connected to sensorial experience. We draw some possible dialogues, as well as point out some differences between the authors, considering the different theoretical contexts to which they belong.
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Granone, Luis Ignacio [Verfasser], Detlef W. [Akademischer Betreuer] Bahnemann, Nadja-C. [Akademischer Betreuer] Bigall, and Cecilia B. [Akademischer Betreuer] Mendive. "An iron-based photoelectrode / Luis Ignacio Granone ; Detlef W. Bahnemann, Nadja-C. Bigall, Cecilia B. Mendive." Hannover : Gottfried Wilhelm Leibniz Universität Hannover, 2019. http://d-nb.info/1195136951/34.

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Arp, Johannes Emil [Verfasser], and Christian B. W. [Akademischer Betreuer] Stark. "Beiträge zur Totalsynthese von 3-O-Me-Premonensin / Johannes Emil Arp ; Betreuer: Christian B. W. Stark." Hamburg : Staats- und Universitätsbibliothek Hamburg, 2017. http://d-nb.info/1147969132/34.

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Bosse, Birgit [Verfasser], S. [Akademischer Betreuer] Bachmann, B. [Akademischer Betreuer] Strauß, and W. [Akademischer Betreuer] Mau. "Aspekte des Körpererlebens bei verschiedenen Subgruppen von Schmerzpatienten / Birgit Bosse. Betreuer: S. Bachmann ; B. Strauß ; W. Mau." Halle, Saale : Universitäts- und Landesbibliothek Sachsen-Anhalt, 2013. http://d-nb.info/1043480587/34.

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Books on the topic "Robinson, D. W. B"

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Raman, Bitshamoon, ed. Símtā d-matle w-ḥašḥātā ʻammāye d-Atúrāye: 2500 matle w-ḥašḥātā múplaḥā b-Atúraye d-idyúm. Sān Húzé, Kālíforniyā: Adiabene Publications, 2004.

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Mammoo, Michael. Dāšnā d-ʻeʼdá: Haqyat krítā b-lešānā Atúrāyā w-Swídíyā. Huskvarna: M. Mammoo, 1987.

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Bazzi, Michael J. Ktābā d-túrāṣ mamllā w-qeryānā d-lešānā Ārāmāyā - ḥadtā: Kaldāyā Súret lešānā d-Kaldāye da-mdínātā w-qúryā d-Nínwe b-Bét Nahrín : ktābā trínā. El Cajon, Ca: St. Peter Chaldean Catholic Church, 2002.

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Lööf, Margareta. Lottas dagbok: Ktābā d-ʻúhdāne d-Loṭṭā / syāmā w-ṣúrātā, Margaritā Lúp ; ittʻabar l-Súryāyā b-yad, Ilyaʼs Šaʼhín. Jönköping: Assyriska tryckeriet, 1997.

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Šemʻún, Yonātān. Egaryātā d-Pawlos šlíḥā: Qā yawmāne príše d-kulāh šentā ayk ṭaksā d-ʻEdtā Šlíḥaytā Qātolíqí d-Madnḥā ; mṭúkasā w-ʼasírā b-yad šamāšā Yonātān Šemʻún. Šíkago [Chicago]: [publisher not identified], 1997.

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Glatzel, G. Pages 357-362 in D. G. Walker, C. B. Powter, and M. W. Pole (Comp). S.l: s.n, 1989.

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Goldstein, Judith S. Tragedies & triumphs: Charles W. Eliot, George B. Dorr, John D. Rockefeller, Jr., the founding of Acadia National Park. Somesville, Me: Port in a Storm Bookstore, 1992.

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Towers of myth and stone: Yeats's influence on Robinson Jeffers. Columbia: University of South Carolina Press, 2015.

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Qermez, Juhanon Seven. Ktāwā da-qeryāne, maʼ egrātā d-Pawlos ʼú šlíḥā d-kāmeqren ba-Ḥúšābe w-ba-ʻeʼde mārānāye b-í šantā kulah: K-dú ṭeksā d-í ʻidtā Súryāytā Ārtdāwksāytā d-Anṭiyúkiyaʼ = The prophet Isaiah and the epistles of St. Paul. Súdertelye, Swéd [Södertälje, Sweden]: Gabriʼíl Yalgen, 2006.

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Crooks, D. W. T. (David W. T.) and Ulster Historical Foundation, eds. Clergy of Killaloe, Kilfenora, Clonfert and Kilmacduagh: Biographical succession lists / compiled by J. B. Leslie and revised, edited and updated by D. W. T. Crooks. Belfast: Ulster Historical Foundation, 2010.

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Book chapters on the topic "Robinson, D. W. B"

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Gänzl, Kurt. "ROBINSON, George (b Northampton, c1799; d Pentonville, London, 11 December 1857)." In Victorian Vocalists, 580–82. First edition. | Abingdon, Oxon ; New York, NY : Routledge, 2017.: Routledge, 2017. http://dx.doi.org/10.4324/9781315102962-75.

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Kiely, Declan D. "Alasdair D. F. Macrae, W. B. Yeats: A Literary Life." In Yeats Annual No. 13, 367–69. London: Palgrave Macmillan UK, 1998. http://dx.doi.org/10.1007/978-1-349-14614-7_20.

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Queiroz, Kevin de, Philip D. Cantino, and Jacques A. Gauthier. "Anthocerotae W. Mitten 1855 [B. D. Mishler, D. C. Cargill, J. C. Villarreal, K. Renzaglia, B. Crandall-Stotler, and R. Stotler],converted clade name." In Phylonyms, 223–26. Boca Raton : CRC Press, [2019]: CRC Press, 2020. http://dx.doi.org/10.1201/9780429446276-53.

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Orel, Harold. "W. B. Maxwell, Time Gathered: Autobiography (New York: D. Appleton-Century, 1938) pp. 189–91." In Sir Arthur Conan Doyle, 166–68. London: Palgrave Macmillan UK, 1991. http://dx.doi.org/10.1007/978-1-349-21487-7_34.

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Queiroz, Kevin de, Philip D. Cantino, and Jacques A. Gauthier. "Charophyta E. F. A. W. Migula 1897: 94 [K. G. Karol, R. M. McCourt, B. D. Mishler, C. F. Delwiche and J. D. Hall], converted clade name." In Phylonyms, 187–90. Boca Raton : CRC Press, [2019]: CRC Press, 2020. http://dx.doi.org/10.1201/9780429446276-43.

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Queiroz, Kevin de, Philip D. Cantino, and Jacques A. Gauthier. "Pleurodira E. D. Cope 1865 [W. G. Joyce, J. F. Parham, J. Anquetin, J. Claude, I. G. Danilov, J. B. Iverson, B. Kear, T. R. Lyson, M. Rabi, and J. Sterli], converted clade name." In Phylonyms, 1055–58. Boca Raton : CRC Press, [2019]: CRC Press, 2020. http://dx.doi.org/10.1201/9780429446276-251.

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Queiroz, Kevin de, Philip D. Cantino, and Jacques A. Gauthier. "Cryptodira E. D. Cope 1868 [W. G. Joyce, J. F. Parham, J. Anquetin, J. Claude, I. G. Danilov, J. B. Iverson, B. Kear, T. R. Lyson, M. Rabi, and J. Sterli], converted clade name." In Phylonyms, 1061–64. Boca Raton : CRC Press, [2019]: CRC Press, 2020. http://dx.doi.org/10.1201/9780429446276-253.

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Carley, Paul, and Inger M. Mees. "The familiar consonants /p b t d k ɡ f v s z h m n w l r/ and the vowels /ɪ æ ɛ ə ʊ/." In American English Phonetic Transcription, 3–8. Abingdon, Oxon; New York, NY: Routledge, 2021.: Routledge, 2021. http://dx.doi.org/10.4324/9781003008088-2.

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Carley, Paul, and Inger M. Mees. "The familiar consonants /p b t d k ɡ f v s z h m n w l r/ and the vowels /ɪ æ e ɒ ʌ ʊ/." In British English Phonetic Transcription, 3–8. Abingdon, Oxon; New York, N.Y.: Routledge, 2021.: Routledge, 2021. http://dx.doi.org/10.4324/9781003007890-2.

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Wordsworth, Dorothy. "601. D. W. to Henry Crabb Robinson." In The Letters of William and Dorothy Wordsworth, Vol. 3: The Middle Years: Part II: 1812–1820 (Second Revised Edition), edited by Ernest De Selincourt, Alan G. Hill, and Mary Moorman, 627–28. Oxford University Press, 2000. http://dx.doi.org/10.1093/oseo/instance.00087476.

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Conference papers on the topic "Robinson, D. W. B"

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Kim, Yong Tae, Chang Woo Lee, and Dong Joon Kim. "High Performance of W-B-N Schottky Contact to GaAs." In 1997 International Conference on Solid State Devices and Materials. The Japan Society of Applied Physics, 1997. http://dx.doi.org/10.7567/ssdm.1997.d-9-6.

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Shen, Guowu, William R. Tyson, and James A. Gianetto. "CMOD Compliance of B×B Single Edge Bend Specimens." In ASME 2012 Pressure Vessels and Piping Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/pvp2012-78037.

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In ASTM standard E1820, the single edge bend (SE(B)) geometry is one of those recommended for fracture toughness testing. The width to thickness (W/B) ratio recommended in E1820 for this specimen is 2. However, in certain cases, it is desirable to use specimens having alternative W/B ratios; the range of W/B suggested in E1820 is 1 to 4. In E1820, the crack size a may be evaluated during J-integral or CTOD resistance testing using the crack mouth opening displacement (CMOD) elastic unloading compliance C. The equation given to relate a to C using a dimensionless compliance BCE incorporates Young’s modulus E. For the three-dimensional (3-D) SE(B) specimens that are in neither plane stress nor plane strain condition, this parameter E may be considered as a normalizing parameter varying between extremes E (plane stress) and E/(1−ν2) (plane strain) depending on crack depth (a/W) and specimen W/B ratio. In the present study, 3-D finite element analysis (FEA) was used to evaluate the CMOD compliance of B×B SE(B) specimens with shallow and deep cracks and compared with that from Tada’s plane stress equation. Crack sizes evaluated using plane stress and plane strain assumptions with the 3-D CMOD compliance obtained from FEA were compared with the actual crack size of the specimens used in FEA. It was found that the errors in crack size using plane strain or plane stress assumptions can be larger than 5%, especially for shallow-cracked specimens. In the present study, an effective modulus with values between plane stress and plane strain is proposed and evaluated by FEA for the 3-D B×B SE(B) specimens. The values were fitted to a polynomial equation as a function of u = 1/(√(BCE)+1) for use in estimating the dimensionless compliance for crack size evaluation for B×B SE(B) specimens. It is shown that the errors in crack size evaluation can be significantly reduced using this effective modulus.
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de Souza, Rodolfo F., and Claudio Ruggieri. "Revised η-Factors for 3P SE(B) Fracture Specimens Incorporating 3-D Effects." In ASME 2014 Pressure Vessels and Piping Conference. American Society of Mechanical Engineers, 2014. http://dx.doi.org/10.1115/pvp2014-28135.

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Standardized procedures to measure cleavage fracture toughness of ferritic steels in the DBT region most commonly employ three-point bend fracture specimens, conventionally termed SE(B) or SENB specimens. The evaluation protocol of fracture toughness for these crack configurations builds upon laboratory records of load and crack mouth opening displacement (CMOD) to relate plastic work with J (or, equivalently, CTOD). The experimental approach employs a plastic η-factor to relate the macroscale crack driving force to the area under the load versus crack mouth opening displacement for cracked configurations. This work provides revised η-factors derived from CMOD records applicable to estimate the J-integral and CTOD in SE(B) specimens with varying crack size and specimen configuration. Non-linear finite element analyses for plane-strain and 3-D models provide the evolution of load with increased CMOD which is required for the estimation procedure. The analysis matrix considers SE(B) specimens with W = 2B and W = B configurations with and without side grooves covering a wide range of specimen thickness, including precracked Charpy (PCVN) specimens. Overall, the present results provide further validation of the J and CTOD evaluation procedure currently adopted by ASTM 1820 while, at the same time, giving improved estimation equations for J incorporating 3-D effects which enter directly into more accurate testing protocols for experimental measurements of fracture toughness values using 3P SE(B) specimens.
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Donato, Gustavo Henrique B., and Felipe Cavalheiro Moreira. "Improved Compliance Solutions for C(T), SE(B) and Clamped SE(T) Specimens Including Side-Grooves, Varying Thicknesses and 3-D Effects." In ASME 2014 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2014. http://dx.doi.org/10.1115/imece2014-39513.

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Fracture toughness and Fatigue Crack Growth (FCG) experimental data represent the basis for accurate designs and integrity assessments of components containing crack-like defects. Considering ductile and high toughness structural materials, crack growing curves (e.g. J-R curves) and FCG data (in terms of da/dN vs. ΔK or ΔJ) assumed paramount relevance since characterize, respectively, ductile fracture and cyclic crack growth conditions. In common, these two types of mechanical properties severely depend on real-time and precise crack size estimations during laboratory testing. Optical, electric potential drop or (most commonly) elastic unloading compliance (C) techniques can be employed. In the latter method, crack size estimation derives from C using a dimensionless parameter (μ) which incorporates specimen’s thickness (B), elasticity (E) and compliance itself. Plane stress and plane strain solutions for μ are available in several standards regarding C(T), SE(B) and M(T) specimens, among others. Current challenges include: i) real specimens are in neither plane stress nor plane strain - modulus vary between E (plane stress) and E/(1-ν2) (plane strain), revealing effects of thickness and 3-D configurations; ii) furthermore, side-grooves affect specimen’s stiffness, leading to an “effective thickness”. Previous results from current authors revealed deviations larger than 10% in crack size estimations following existing practices, especially for shallow cracks and side-grooved samples. In addition, compliance solutions for the emerging clamped SE(T) specimens are not yet standardized. As a step in this direction, this work investigates 3-D, thickness and side-groove effects on compliance solutions applicable to C(T), SE(B) and clamped SE(T) specimens. Refined 3-D elastic FE-models provide Load-CMOD evolutions. The analysis matrix includes crack depths between a/W=0.1 and a/W=0.7 and varying thicknesses (W/B = 4, W/B = 2 and W/B = 1). Side-grooves of 5%, 10% and 20% are also considered. The results include compliance solutions incorporating all aforementioned effects to provide accurate crack size estimation during laboratory fracture and FCG testing. All proposals revealed reduced deviations if compared to existing solutions.
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Lin, Tao, and David L. Russell. "Estimating the Interaction Kernel in a Mathematical Model for a Beam With Internal Damping Mechanism." In ASME 1995 Design Engineering Technical Conferences collocated with the ASME 1995 15th International Computers in Engineering Conference and the ASME 1995 9th Annual Engineering Database Symposium. American Society of Mechanical Engineers, 1995. http://dx.doi.org/10.1115/detc1995-0675.

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Abstract Beams formed by long fiber composite materials have certain internal damping torque. A mathematical model for the displacement of this type of beams in cantilever configuration is the following initial-boundary value problem of an integro-differential equation [1, 14]: (1) ρ ( x ) w t t ( x , t ) − 2 ( ∫ 0 L h ( x , y ) [ w t x ( x , t ) − w t x ( y , t ) ] d y ) x + ( E I w x x ( x , t ) ) x x = f ( x , t ) , (2) w ( 0 , t ) = 0 , w x ( 0 , t ) = 0 , (3) w x x ( L , t ) = b l 1 ( t ) , (4) − ( E I w x x ( x , t ) ) x | x = L + 2 ∫ 0 L h ( L , y ) [ w t x ( L , t ) − w t x ( y , t ) ] d y = b l 2 ( t ) , (5) w ( x , 0 ) = w 0 ( x ) , w t ( x , 0 ) = w 1 ( x ) , where L is length of the beam, w(x, t) is the transverse displacement of the beam at time t and position x, ρ(x) is the mass density, EI is the stiffness parameter. The interaction integral kernel h(x, ξ) is introduced in this model by considering a restoring torque which comes from spatially variable bending of the beam. This kernel h(x, ξ) depends on the material properties of the beam. Choosing a different material (different h(x, ξ)) can realize a different damping effect for the beam.
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Nishi, Yoshihisa, Kenichi Kanda, Kazuma Abe, Satoshi Nishimura, Koichi Nakamura, Masahiro Furuya, and Atsushi Ui. "Severe Accident Analysis With Spatial Discretized Model by MAAP: Part 2 — Parametric Study on Fukushima-Daiichi Unit-3." In 2018 26th International Conference on Nuclear Engineering. American Society of Mechanical Engineers, 2018. http://dx.doi.org/10.1115/icone26-82018.

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Accident analyses of unit 3 in the Fukushima-Daiichi nuclear power station were performed with MAAP (Modular Accident Analysis Program) 5.03. In the analysis, the operations of RCIC, HPCI, SRV were simulated and assuming the operation of alternative water injection to reproduce the measured pressure and temperature. As a result of parametric evaluation, analysis results consistent with measured values are obtained. In this paper, the results of the sensitivity analysis are reported. Simultaneously, attempts were made to analyze the transient and deposition amount of fission product (FP) in the reactor building (R/B) and a model dividing each room of R/B in detail was created to confirm the FP behavior. Based on these analyses, the deposition amount of the primary containment vessel (PCV) (drywell (D/W) and wetwell (W/W)) and R/B could be estimated using detailed model of the R/B dividing into nodes in the MAAP simulation.
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Donato, Gustavo Henrique B., and Felipe Cavalheiro Moreira. "Effects of Side-Grooves and 3-D Geometries on Compliance Solutions and Crack Size Estimations Applicable to C(T), SE(B) and Clamped SE(T) Specimens." In ASME 2013 Pressure Vessels and Piping Conference. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/pvp2013-98018.

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Engineering procedures for design and integrity assessment of structural components containing crack-like defects are highly dependent on accurate fracture toughness and Fatigue Crack Growth (FCG) experimental data. Considering ductile and high toughness structural materials, crack growing curves (e.g. J-R curves) and FCG data (in terms of da/dN vs. ΔK or ΔJ) assumed paramount relevance. In common, these two types of mechanical properties severely depend on real-time and precise crack size estimations during laboratory testing. Optical measurement, electric potential drop or (most commonly) elastic unloading compliance (C) techniques can be employed. In the latter method, crack size estimation derives from C using a dimensionless parameter (μ) which incorporates specimen’s thickness (B), elasticity (E) and compliance itself. Plane stress and plane strain solutions for μ are available in several standards regarding C(T), SE(B) and M(T) specimens, among others. Current challenges include: i) real specimens are in neither plane stress nor plane strain-modulus vary between E (plane stress) and E/(1−ν2) (plane strain); ii) furthermore, side-grooves affect specimen’s stiffness, leading to an “effective thickness”. Results from Shen et al. and from current authors revealed deviations larger than 10% in crack size estimations following existing practices, especially for shallow cracks and side-grooved samples. In addition, compliance solutions for the emerging SE(T) specimens are not yet standardized. As a step in this direction, this work investigates 3-D and side-groove effects on compliance solutions applicable to C(T), SE(B) and clamped SE(T) specimens. Refined 3-D elastic FE-models provide Load-CMOD evolutions. The analysis matrix includes crack depths between a/W = 0.1 and a/W = 0.7 on 1/2T, 1T and 2T geometries. The 1T geometry is taken as the reference and presents width to thickness ratio W/B = 2. Side-grooves of 5%, 10% and 20% are considered. The results include compliance solutions incorporating 3D and side-groove effects to provide accurate crack size estimation during laboratory fracture and FCG testing. The proposals were verified against current standardized solutions and deviations were strongly reduced.
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Smadi, Othman, Ibrahim Hassan, Philippe Pibarot, and Lyes Kadem. "Bileaflet Prosthetic Heart Valve Disease: Numerical Approach Using 3-D Fluid-Structure Interaction Model With Realistic Aortic Root." In ASME 2010 3rd Joint US-European Fluids Engineering Summer Meeting collocated with 8th International Conference on Nanochannels, Microchannels, and Minichannels. ASMEDC, 2010. http://dx.doi.org/10.1115/fedsm-icnmm2010-31203.

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Surgical replacement, in the incidence of severely diseased heart valve, is vital in order to restore the normal heart function. Every year around 280,000 valve replacements occur around the world, half of them are bileaflet mechanical heart valves (BMHVs). Despite the remarkable improvement in valve design resulting in minimizing prosthetic valve complications (thromboembolic events or pannus formation), these complications are still possible with BMHV Implantation. As a consequence, an obstruction in one or both MHV leaflets could happen and threaten the patient life. In the present study, an obstructed bileaflet MHV with different percentages of malfunction was simulated assuming 3-D fluid structure interaction (FSI) adapting k-w turbulence as a robust model for the transitional flow using 2.5 million elements and creating a realistic aortic root model with three sinuses. Velocity contours for different percentages of malfunction were compared mainly at B-datum plane and the perpendicular plane to the B-Datum. Also, the development of coherent structures was investigated. Clinically, the maximum pressure gradients were estimated by mimicking the Echo Doppler assumptions (using the simplified Bernoulli equation).
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Hata, Koichi, Katsuya Fukuda, and Tohru Mizuuchi. "Natural Convection Heat Transfer From Vertical 5×5 Rod Bundles in Liquid Sodium." In 2016 24th International Conference on Nuclear Engineering. American Society of Mechanical Engineers, 2016. http://dx.doi.org/10.1115/icone24-60180.

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Natural convection heat transfer from vertical 5×5 rod bundles in liquid sodium was numerically analyzed for two types of the bundle geometry (equilateral square and triangle arrays, ESA and ETA). The unsteady laminar three dimensional basic equations for natural convection heat transfer caused by a step heat flux were numerically solved until the solution reaches a steady-state. The PHOENICS code was used for the calculation considering the temperature dependence of thermophysical properties concerned. The 5×5 test rods for diameter (D = 7.6 mm), heated length (L = 200 mm) and L/d (= 26.32) were used in this work. The surface heat fluxes for each cylinder were equally given for a modified Rayleigh number, (Rf,L)ij and (Rf,L)5×5,S/D, ranging from 3.08 × 104 to 4.19 × 107 (q = 1 × 104∼7 × 106 W/m2) in liquid temperature (TL = 673.15 K). The values of S/D, which are ratios of the diameter of flow channel for bundle geometry to the rod diameter, for vertical 5×5 rod bundles were ranged from 1.8 to 6 on each bundle geometry. The spatial distribution of local and average Nusselt numbers, (Nuav)ij and (Nuav,B)5×5,S/D, on vertical rods of a bundle was clarified. The average value of Nusselt number, (Nuav)ij and (Nuav,B)5×5,S/D, for two types of the bundle geometry with various values of S/D were calculated to examine the effect of the bundle geometry, S/D, (Rf,L)ij and (Rf,L)5×5,S/D on heat transfer. The bundle geometry for the higher (Nuav,B)5×5,S/D value under the condition of S/D = constant was examined. The correlations for (Nuav,B)5×5,S/D for two types of bundle geometry above mentioned including the effects of (Rf,L)5×5,S/D and S/D were developed. The correlations can describe the theoretical values of (Nuav,B)5×5,S/D for two types of the bundle geometry for S/D ranging from 1.8 to 6 within −11.77 to 13.34 % difference.
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Bumanis, Girts, Jelizaveta Zorica, Ina Pundienė, and Diana Bajare. "The workability kinetics of phosphogypsum binder." In The 13th international scientific conference “Modern Building Materials, Structures and Techniques”. Vilnius Gediminas Technical University, 2019. http://dx.doi.org/10.3846/mbmst.2019.103.

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The dihydrate phosphogypsum (PG) based binder workability kinetics were investigated regarding to waterbinder ratio (W/B) and chemical admixtures added to the composition of PG paste. PG was dried at 60 °C and homogenized to powder like particles with collision milling in disintegrator and calcium sulphate hemihydrate was obtained by heating PG at 180 °C. The obtained binder chemical, mineralogical and technological properties were tested and compared to commercial gypsum plaster. Early age (2 h) and 14 d compression strength was determined. The workability and setting time of both – PG and commercial gypsum was investigated with viscosimeter, ultrasonic pulse velocity and Vicat apparatus and correlation between testing methods was obtained. Results indicate that binder based on PG has slightly lower pH (pH 6.3) than commercial binder (pH 6.8) and finer particle size grading leading to increased W/B ratio and more rapid initial setting time. The set retarder could efficiently increase the setting time of PG binder giving extra workability time which is positive factor for prolonged treatment of binder slurry, i.e. to prepare porous gypsum binder. Such approach would give a safer alternative to PG disposal, closing the materials loop and enhancing the circularity of this material.
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Reports on the topic "Robinson, D. W. B"

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Shomer, Ilan, Ruth E. Stark, Victor Gaba, and James D. Batteas. Understanding the hardening syndrome of potato (Solanum tuberosum L.) tuber tissue to eliminate textural defects in fresh and fresh-peeled/cut products. United States Department of Agriculture, November 2002. http://dx.doi.org/10.32747/2002.7587238.bard.

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The project sought to understand factors and mechanisms involved in the hardening of potato tubers. This syndrome inhibits heat softening due to intercellular adhesion (ICA) strengthening, compromising the marketing of industrially processed potatoes, particularly fresh peeled-cut or frozen tubers. However, ICA strengthening occurs under conditions which are inconsistent with the current ideas that relate it to Ca-pectate following pectin methyl esterase (PME) activity or to formation of rhamnogalacturonan (RG)-II-borate. First, it was necessary to induce strengthening of the middle lamellar complex (MLX) and the ICA as a stress response in some plant parenchyma. As normally this syndrome does not occur uniformly enough to study it, we devised an efficient model in which ICA-strengthening is induced consistently under simulated stress by short-chain, linear, mono-carboxylic acid molecules (OAM), at 65 oC [appendix 1 (Shomer&Kaaber, 2006)]. This rapid strengthening was insufficient for allowing the involved agents assembly to be identifiable; but it enabled us to develop an efficient in vitro system on potato tuber parenchyma slices at 25 ºC for 7 days, whereas unified stress was reliably simulated by OAMs in all the tissue cells. Such consistent ICA-strengthening in vitro was found to be induced according to the unique physicochemical features of each OAM as related to its lipophilicity (Ko/w), pKa, protonated proportion, and carbon chain length by the following parameters: OAM dissociation constant (Kdiss), adsorption affinity constant (KA), number of adsorbed OAMs required for ICA response (cooperativity factor) and the water-induced ICA (ICAwater). Notably, ICA-strengthening is accompanied by cell sap leakage, reflecting cell membrane rupture. In vitro, stress simulation by OAMs at pH<pKa facilitated the consistent assembly of ICAstrengthening agents, which we were able to characterize for the first time at the molecular level within purified insoluble cell wall of ICA-strengthened tissue. (a) With solid-state NMR, we established the chemical structure and covalent binding to cell walls of suberin-like agents associated exclusively with ICA strengthening [appendix 3 (Yu et al., 2006)]; (b) Using proteomics, 8 isoforms of cell wall-bound patatin (a soluble vacuolar 42-kDa protein) were identified exclusively in ICA-strengthened tissue; (c) With light/electron microscopy, ultrastructural characterization, histochemistry and immunolabeling, we co-localized patatin and pectin in the primary cell wall and prominently in the MLX; (d) determination of cell wall composition (pectin, neutral sugars, Ca-pectate) yielded similar results in both controls and ICA-strengthened tissue, implicating factors other than PME activity, Ca2+ or borate ions; (e) X-ray powder diffraction experiments revealed that the cellulose crystallinity in the cell wall is masked by pectin and neutral sugars (mainly galactan), whereas heat or enzymatic pectin degradation exposed the crystalline cellulose structure. Thus, we found that exclusively in ICA-strengthened tissue, heat-resistant pectin is evident in the presence of patatin and suberinlike agents, where the cellulose crystallinity was more hidden than in fresh control tissue. Conclusions: Stress response ICA-strengthening is simulated consistently by OAMs at pH< pKa, although PME and formation of Ca-pectate and RG-II-borate are inhibited. By contrast, at pH>pKa and particularly at pH 7, ICA-strengthening is mostly inhibited, although PME activity and formation of Ca-pectate or RG-II-borate are known to be facilitated. We found that upon stress, vacuolar patatin is released with cell sap leakage, allowing the patatin to associate with the pectin in both the primary cell wall and the MLX. The stress response also includes formation of covalently bound suberin-like polyesters within the insoluble cell wall. The experiments validated the hypotheses, thus led to a novel picture of the structural and molecular alterations responsible for the textural behavior of potato tuber. These findings represent a breakthrough towards understanding of the hardening syndrome, laying the groundwork for potato-handling strategies that assure textural quality of industrially processed particularly in fresh peeled cut tubers, ready-to-prepare and frozen preserved products.
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