Journal articles on the topic 'Ribonucleotide kinase'
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Chen, Frank Y., Francis M. Amara, and Jim A. Wright. "Posttranscriptional regulation of ribonucleotide reductase R1 gene expression is linked to a protein kinase C pathway in mammalian cells." Biochemistry and Cell Biology 72, no. 7-8 (July 1, 1994): 251–56. http://dx.doi.org/10.1139/o94-036.
Full textMerdanovic, Melisa, Elizabeta Sauer, and Joachim Reidl. "Coupling of NAD+ Biosynthesis and Nicotinamide Ribosyl Transport: Characterization of NadR Ribonucleotide Kinase Mutants of Haemophilus influenzae." Journal of Bacteriology 187, no. 13 (July 1, 2005): 4410–20. http://dx.doi.org/10.1128/jb.187.13.4410-4420.2005.
Full textDubacq, Caroline, Anne Chevalier, and Carl Mann. "The Protein Kinase Snf1 Is Required for Tolerance to the Ribonucleotide Reductase Inhibitor Hydroxyurea." Molecular and Cellular Biology 24, no. 6 (March 15, 2004): 2560–72. http://dx.doi.org/10.1128/mcb.24.6.2560-2572.2004.
Full textKlein, Beate, and Hartmut Follmann. "Deoxyribonucleotide Biosynthesis in Green Algae. S Phase-Specific Thymidylate Kinase and Unspecific Nucleoside Diphosphate Kinase in Scenedesmus obliquus." Zeitschrift für Naturforschung C 43, no. 5-6 (June 1, 1988): 377–85. http://dx.doi.org/10.1515/znc-1988-5-610.
Full textHiller, Bjoern, Martin Achleitner, Silke Glage, Ronald Naumann, Rayk Behrendt, and Axel Roers. "Mammalian RNase H2 removes ribonucleotides from DNA to maintain genome integrity." Journal of Experimental Medicine 209, no. 8 (July 16, 2012): 1419–26. http://dx.doi.org/10.1084/jem.20120876.
Full textDavies, Lawrence C., John A. Stock, S. Elaine Barrie, Rosanne M. Orr, and Kenneth R. Harrap. "Dinucleotide analogs as inhibitors of thymidine kinase, thymidylate kinase and ribonucleotide reductase." Journal of Medicinal Chemistry 31, no. 7 (July 1988): 1305–8. http://dx.doi.org/10.1021/jm00402a008.
Full textChen, F. Y., F. M. Amara, and J. A. Wright. "Regulation of mammalian ribonucleotide reductase R1 mRNA stability is mediated by a ribonucleotide reductase R1 mRNA 3′-untranslated region cis-trans interaction through a protein kinase C-controlled pathway." Biochemical Journal 302, no. 1 (August 15, 1994): 125–32. http://dx.doi.org/10.1042/bj3020125.
Full textHurta, Robert A. R., and Jim A. Wright. "Regulation of mammalian ribonucleotide reductase by the tumor promoters and protein phosphatase inhibitors okadaic acid and calyculin A." Biochemistry and Cell Biology 70, no. 10-11 (October 1, 1992): 1081–87. http://dx.doi.org/10.1139/o92-153.
Full textEaton, Jana S., Z. Ping Lin, Alan C. Sartorelli, Nicholas D. Bonawitz, and Gerald S. Shadel. "Ataxia-telangiectasia mutated kinase regulates ribonucleotide reductase and mitochondrial homeostasis." Journal of Clinical Investigation 117, no. 9 (September 4, 2007): 2723–34. http://dx.doi.org/10.1172/jci31604.
Full textLin, Fumin, Thomas J. Ribar, and Anthony R. Means. "The Ca2+/Calmodulin-Dependent Protein Kinase Kinase, CaMKK2, Inhibits Preadipocyte Differentiation." Endocrinology 152, no. 10 (August 23, 2011): 3668–79. http://dx.doi.org/10.1210/en.2011-1107.
Full textKramata, Pavel, and Ivan Votruba. "Enzymes of Human Herpesviruses." Collection of Czechoslovak Chemical Communications 57, no. 8 (1992): 1577–612. http://dx.doi.org/10.1135/cccc19921577.
Full textPaik, Sehmi, Lauren Senty, Sankar Das, Jody C. Noe, Cindy L. Munro, and Todd Kitten. "Identification of Virulence Determinants for Endocarditis in Streptococcus sanguinis by Signature-Tagged Mutagenesis." Infection and Immunity 73, no. 9 (September 2005): 6064–74. http://dx.doi.org/10.1128/iai.73.9.6064-6074.2005.
Full textZhao, Xiaolan, and Rodney Rothstein. "The Dun1 checkpoint kinase phosphorylates and regulates the ribonucleotide reductase inhibitor Sml1." Proceedings of the National Academy of Sciences 99, no. 6 (March 19, 2002): 3746–51. http://dx.doi.org/10.1073/pnas.062502299.
Full textChan, Arthur K., Sujata Persad, David W. Litchfield, and Jim A. Wright. "Ribonucleotide reductase R2 protein is phosphorylated at serine-20 by P34cdc2 kinase." Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1448, no. 3 (January 1999): 363–71. http://dx.doi.org/10.1016/s0167-4889(98)00115-3.
Full textDownes, C. S., C. Z. Bachrati, S. J. Devlin, M. Tommasino, T. J. Cutts, J. V. Watson, I. Rasko, and R. T. Johnson. "Mammalian S-phase checkpoint integrity is dependent on transformation status and purine deoxyribonucleosides." Journal of Cell Science 113, no. 6 (March 15, 2000): 1089–96. http://dx.doi.org/10.1242/jcs.113.6.1089.
Full textNguyen, Alexandra, Melanie Dzulko, Janine Murr, Yun Yen, Günter Schneider, and Oliver H. Krämer. "Class 1 Histone Deacetylases and Ataxia-Telangiectasia Mutated Kinase Control the Survival of Murine Pancreatic Cancer Cells upon dNTP Depletion." Cells 10, no. 10 (September 23, 2021): 2520. http://dx.doi.org/10.3390/cells10102520.
Full textLiu, Li, Jiri Veis, Wolfgang Reiter, Edwin Motari, Catherine E. Costello, John C. Samuelson, Gustav Ammerer, and David E. Levin. "Regulation of Pkc1 Hyper-Phosphorylation by Genotoxic Stress." Journal of Fungi 7, no. 10 (October 17, 2021): 874. http://dx.doi.org/10.3390/jof7100874.
Full textSanvisens, N., A. M. Romero, X. An, C. Zhang, R. de Llanos, M. T. Martinez-Pastor, M. C. Bano, M. Huang, and S. Puig. "Yeast Dun1 Kinase Regulates Ribonucleotide Reductase Inhibitor Sml1 in Response to Iron Deficiency." Molecular and Cellular Biology 34, no. 17 (June 23, 2014): 3259–71. http://dx.doi.org/10.1128/mcb.00472-14.
Full textBRACCHI-RICARD, Valerie, Sailen BARIK, Cherie DELVECCHIO, Christian DOERIG, Ratna CHAKRABARTI, and Debopam CHAKRABARTI. "PfPK6, a novel cyclin-dependent kinase/mitogen-activated protein kinase-related protein kinase from Plasmodium falciparum." Biochemical Journal 347, no. 1 (March 27, 2000): 255–63. http://dx.doi.org/10.1042/bj3470255.
Full textTsao, Ning, Ya-Chi Yang, Yu-Jyun Deng, and Zee-Fen Chang. "The direct interaction of NME3 with Tip60 in DNA repair." Biochemical Journal 473, no. 9 (April 26, 2016): 1237–45. http://dx.doi.org/10.1042/bcj20160122.
Full textSanvisens, Nerea, Antonia M. Romero, Caiguo Zhang, Xiaorong Wu, Xiuxiang An, Mingxia Huang, and Sergi Puig. "Yeast Dun1 Kinase Regulates Ribonucleotide Reductase Small Subunit Localization in Response to Iron Deficiency." Journal of Biological Chemistry 291, no. 18 (March 12, 2016): 9807–17. http://dx.doi.org/10.1074/jbc.m116.720862.
Full textAlbert, Daniel A., and Edwardine Nodzenski. "M2 subunit of ribonucleotide reductase is a target of cyclic AMP-dependent protein kinase." Journal of Cellular Physiology 138, no. 1 (January 1989): 129–36. http://dx.doi.org/10.1002/jcp.1041380118.
Full textBoccalatte, Francesco E., Claudia Voena, Chiara Riganti, Amalia Bosia, Lucia D'Amico, Ludovica Riera, Mangeng Cheng, et al. "The enzymatic activity of 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase is enhanced by NPM-ALK: new insights in ALK-mediated pathogenesis and the treatment of ALCL." Blood 113, no. 12 (March 19, 2009): 2776–90. http://dx.doi.org/10.1182/blood-2008-06-161018.
Full textGuetsova, Maria L., Karine Lecoq, and Bertrand Daignan-Fornier. "The Isolation and Characterization of Saccharomyces cerevisiae Mutants That Constitutively Express Purine Biosynthetic Genes." Genetics 147, no. 2 (October 1, 1997): 383–97. http://dx.doi.org/10.1093/genetics/147.2.383.
Full textPiao, C., M. Jin, H. B. Kim, S. M. Lee, P. N. Amatya, J. W. Hyun, I. Y. Chang, and H. J. You. "Ribonucleotide reductase small subunit p53R2 suppresses MEK–ERK activity by binding to ERK kinase 2." Oncogene 28, no. 21 (April 27, 2009): 2173–84. http://dx.doi.org/10.1038/onc.2009.84.
Full textZhang, Yong-Wei, Tamara L. Jones, Scott E. Martin, Natasha J. Caplen, and Yves Pommier. "Implication of Checkpoint Kinase-dependent Up-regulation of Ribonucleotide Reductase R2 in DNA Damage Response." Journal of Biological Chemistry 284, no. 27 (May 5, 2009): 18085–95. http://dx.doi.org/10.1074/jbc.m109.003020.
Full textMilho, Ricardo, Michael B. Gill, Janet S. May, Susanna Colaco, and Philip G. Stevenson. "In vivo function of the murid herpesvirus-4 ribonucleotide reductase small subunit." Journal of General Virology 92, no. 7 (July 1, 2011): 1550–60. http://dx.doi.org/10.1099/vir.0.031542-0.
Full textCorda, Yves, Sang Eun Lee, Sylvine Guillot, André Walther, Julie Sollier, Ayelet Arbel-Eden, James E. Haber, and Vincent Géli. "Inactivation of Ku-Mediated End Joining Suppresses mec1Δ Lethality by Depleting the Ribonucleotide Reductase Inhibitor Sml1 through a Pathway Controlled by Tel1 Kinase and the Mre11 Complex." Molecular and Cellular Biology 25, no. 23 (December 1, 2005): 10652–64. http://dx.doi.org/10.1128/mcb.25.23.10652-10664.2005.
Full textAhluwalia, Amrita, Neil Hoa, Michael K. Jones, and Andrzej S. Tarnawski. "NSAID-induced injury of gastric epithelial cells is reversible: roles of mitochondria, AMP kinase, NGF, and PGE2." American Journal of Physiology-Gastrointestinal and Liver Physiology 317, no. 6 (December 1, 2019): G862—G871. http://dx.doi.org/10.1152/ajpgi.00192.2019.
Full textYue, Yingying, Chang Zhang, Xuejiao Zhang, Shitian Zhang, Qian Liu, Fang Hu, Xiaoting Lv, et al. "An AMPK/Axin1-Rac1 signaling pathway mediates contraction-regulated glucose uptake in skeletal muscle cells." American Journal of Physiology-Endocrinology and Metabolism 318, no. 3 (March 1, 2020): E330—E342. http://dx.doi.org/10.1152/ajpendo.00272.2019.
Full textSigmond, Jennifer, Andries M. Bergman, Leticia G. Leon, Willem J. P. Loves, Eveline K. Hoebe, and Godefridus J. Peters. "Staurosporine increases toxicity of gemcitabine in non-small cell lung cancer cells: role of protein kinase C, deoxycytidine kinase and ribonucleotide reductase." Anti-Cancer Drugs 21, no. 6 (July 2010): 591–99. http://dx.doi.org/10.1097/cad.0b013e32833a3543.
Full textTheodoropoulou, Sofia, Paraskevi E. Kolovou, Yuki Morizane, Maki Kayama, Fotini Nicolaou, Joan W. Miller, Evangelos Gragoudas, Bruce R. Ksander, and Demetrios G. Vavvas. "Retinoblastoma cells are inhibited by aminoimidazole carboxamide ribonucleotide (AICAR) partially through activation of AMP‐dependent kinase." FASEB Journal 24, no. 8 (April 6, 2010): 2620–30. http://dx.doi.org/10.1096/fj.09-152546.
Full textBoxem, M., D. G. Srinivasan, and S. van den Heuvel. "The Caenorhabditis elegans gene ncc-1 encodes a cdc2-related kinase required for M phase in meiotic and mitotic cell divisions, but not for S phase." Development 126, no. 10 (May 15, 1999): 2227–39. http://dx.doi.org/10.1242/dev.126.10.2227.
Full textYang, Pei-Ming, Li-Shan Lin, and Tsang-Pai Liu. "Sorafenib Inhibits Ribonucleotide Reductase Regulatory Subunit M2 (RRM2) in Hepatocellular Carcinoma Cells." Biomolecules 10, no. 1 (January 9, 2020): 117. http://dx.doi.org/10.3390/biom10010117.
Full textMarsolier, Marie-Claude, Pascal Roussel, Christophe Leroy, and Carl Mann. "Involvement of the PP2C-Like Phosphatase Ptc2p in the DNA Checkpoint Pathways of Saccharomyces cerevisiae." Genetics 154, no. 4 (April 1, 2000): 1523–32. http://dx.doi.org/10.1093/genetics/154.4.1523.
Full textBhalla, Amit. "Clofarabine: a next-generation deoxyadenosine analogue." International Journal of Basic & Clinical Pharmacology 7, no. 5 (April 23, 2018): 1048. http://dx.doi.org/10.18203/2319-2003.ijbcp20181660.
Full textOLIVER, F. Javier, Mary K. L. COLLINS, and Abelardo LÓPEZ-RIVAS. "Regulation of the salvage pathway of deoxynucleotides synthesis in apoptosis induced by growth factor deprivation." Biochemical Journal 316, no. 2 (June 1, 1996): 421–25. http://dx.doi.org/10.1042/bj3160421.
Full textGao, Jin, and Des R. Richardson. "The potential of iron chelators of the pyridoxal isonicotinoyl hydrazone class as effective antiproliferative agents, IV: the mechanisms involved in inhibiting cell-cycle progression." Blood 98, no. 3 (August 1, 2001): 842–50. http://dx.doi.org/10.1182/blood.v98.3.842.
Full textPons, Miriam, Yanira Zeyn, Stella Zahn, Nisintha Mahendrarajah, Brent D. G. Page, Patrick T. Gunning, Richard Moriggl, Walburgis Brenner, Falk Butter, and Oliver H. Krämer. "Oncogenic Kinase Cascades Induce Molecular Mechanisms That Protect Leukemic Cell Models from Lethal Effects of De Novo dNTP Synthesis Inhibition." Cancers 13, no. 14 (July 10, 2021): 3464. http://dx.doi.org/10.3390/cancers13143464.
Full textMulherin, Andrew J., Amy H. Oh, Helena Kim, Anthony Grieco, Lina M. Lauffer, and Patricia L. Brubaker. "Mechanisms Underlying Metformin-Induced Secretion of Glucagon-Like Peptide-1 from the Intestinal L Cell." Endocrinology 152, no. 12 (October 4, 2011): 4610–19. http://dx.doi.org/10.1210/en.2011-1485.
Full textJian, Ming-Yuan, Yanping Liu, Qian Li, Paul Wolkowicz, Mikhail Alexeyev, Jaroslaw Zmijewski, and Judy Creighton. "N-cadherin coordinates AMP kinase-mediated lung vascular repair." American Journal of Physiology-Lung Cellular and Molecular Physiology 310, no. 1 (January 1, 2016): L71—L85. http://dx.doi.org/10.1152/ajplung.00227.2015.
Full textChung, T. D., J. P. Wymer, C. C. Smith, M. Kulka, and L. Aurelian. "Protein kinase activity associated with the large subunit of herpes simplex virus type 2 ribonucleotide reductase (ICP10)." Journal of Virology 63, no. 8 (1989): 3389–98. http://dx.doi.org/10.1128/jvi.63.8.3389-3398.1989.
Full textMazumder, Aprotim, Katja Tummler, Mark Bathe, and Leona D. Samson. "Single-Cell Analysis of Ribonucleotide Reductase Transcriptional and Translational Response to DNA Damage." Molecular and Cellular Biology 33, no. 3 (November 26, 2012): 635–42. http://dx.doi.org/10.1128/mcb.01020-12.
Full textVakana, Eliza, Jessica K. Altman, Heather Glaser, Nicholas J. Donato, and Leonidas C. Platanias. "Antileukemic effects of AMPK activators on BCR-ABL–expressing cells." Blood 118, no. 24 (December 8, 2011): 6399–402. http://dx.doi.org/10.1182/blood-2011-01-332783.
Full textLu, Jun, Qinghua Wang, Lianghu Huang, Huiyue Dong, Lingjing Lin, Na Lin, Feng Zheng, and Jianming Tan. "Palmitate Causes Endoplasmic Reticulum Stress and Apoptosis in Human Mesenchymal Stem Cells: Prevention by AMPK Activator." Endocrinology 153, no. 11 (November 1, 2012): 5275–84. http://dx.doi.org/10.1210/en.2012-1418.
Full textCooper, J., J. Conner, and J. B. Clements. "Characterization of the novel protein kinase activity present in the R1 subunit of herpes simplex virus ribonucleotide reductase." Journal of virology 69, no. 8 (1995): 4979–85. http://dx.doi.org/10.1128/jvi.69.8.4979-4985.1995.
Full textAl-Moujahed, Ahmad, Fotini Nicolaou, Katarzyna Brodowska, Thanos D. Papakostas, Anna Marmalidou, Bruce R. Ksander, Joan W. Miller, Evangelos Gragoudas, and Demetrios G. Vavvas. "Uveal Melanoma Cell Growth Is Inhibited by Aminoimidazole Carboxamide Ribonucleotide (AICAR) Partially Through Activation of AMP-Dependent Kinase." Investigative Opthalmology & Visual Science 55, no. 7 (July 8, 2014): 4175. http://dx.doi.org/10.1167/iovs.13-12856.
Full textFerrandina, Gabriella, Valentina Mey, Sara Nannizzi, Simona Ricciardi, Marco Petrillo, Cristiano Ferlini, Romano Danesi, Giovanni Scambia, and Mario Del Tacca. "Expression of nucleoside transporters, deoxycitidine kinase, ribonucleotide reductase regulatory subunits, and gemcitabine catabolic enzymes in primary ovarian cancer." Cancer Chemotherapy and Pharmacology 65, no. 4 (July 29, 2009): 679–86. http://dx.doi.org/10.1007/s00280-009-1073-y.
Full textHolmes, B. F., E. J. Kurth-Kraczek, and W. W. Winder. "Chronic activation of 5′-AMP-activated protein kinase increases GLUT-4, hexokinase, and glycogen in muscle." Journal of Applied Physiology 87, no. 5 (November 1, 1999): 1990–95. http://dx.doi.org/10.1152/jappl.1999.87.5.1990.
Full textHuang, M., and S. J. Elledge. "Identification of RNR4, encoding a second essential small subunit of ribonucleotide reductase in Saccharomyces cerevisiae." Molecular and Cellular Biology 17, no. 10 (October 1997): 6105–13. http://dx.doi.org/10.1128/mcb.17.10.6105.
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