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1

Senthilan, Pingkalai R., and Charlotte Helfrich-Förster. "Rhodopsin 7–The unusual Rhodopsin inDrosophila." PeerJ 4 (September 6, 2016): e2427. http://dx.doi.org/10.7717/peerj.2427.

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Rhodopsins are the major photopigments in the fruit flyDrosophila melanogaster. Drosophilaexpress six well-characterized Rhodopsins (Rh1–Rh6) with distinct absorption maxima and expression pattern. In 2000, when theDrosophilagenome was published, a novelRhodopsingene was discovered:Rhodopsin 7(Rh7).Rh7is highly conserved among theDrosophilagenus and is also found in other arthropods. Phylogenetic trees based on protein sequences suggest that the sevenDrosophilaRhodopsins cluster in three different groups. While Rh1, Rh2 and Rh6 form a “vertebrate-melanopsin-type”–cluster, and Rh3, Rh4 and Rh5 form an “insect-type”-Rhodopsin cluster, Rh7 seem to form its own cluster. Although Rh7 has nearly all important features of a functional Rhodopsin, it differs from other Rhodopsins in its genomic and structural properties, suggesting it might have an overall different role than other known Rhodopsins.
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Noort, Annemarie, Aartjan T. F. Beekman, and Arjan W. Braam. "Religious Hallucinations and Religious Delusions among Older Adults in Treatment for Psychoses in the Netherlands." Religions 11, no. 10 (October 12, 2020): 522. http://dx.doi.org/10.3390/rel11100522.

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Background. Although religious delusions (RDs) are common in geriatric psychiatry, we know little about their frequency and content. Our study examines the prevalence and content of religious hallucinations (RHs) and RDs and how they relate to the diagnosis and the patients’ denominational background and other aspects of religiousness. Methods. Semi-structured diagnostic interviews were conducted with inpatients and outpatients (N = 155, mean age 76.5) at a geriatric psychiatry department in the Netherlands. We used the Schedules for Clinical Assessment in Neuropsychiatry 2.1. Results. The prevalences of RHs and RDs were 19% and 32%, respectively. RHs were mostly auditory. There was no statistically significant difference between the prevalence of RHs in schizophrenia (17.5%) and in psychotic depression (9.4%). Compared to non-affiliated patients and mainline Protestants, RDs were significantly more prevalent in raised and current strict Protestants, especially in those with psychotic depression. RHs were more prevalent in Evangelical (e.g., Pentecostal) and strict Protestant patients. The presence of RDs was associated with several measures of religiousness (e.g., dogmatism, religious coping). Conclusions. Religion is likely to act as a symptom-formation factor for psychotic symptoms in strict Protestant older adults. More detailed research might lead to a fuller understanding of how strict religious beliefs may affect the content of psychotic symptoms and unintentionally add a component of existential suffering. It is important for mental health professionals, especially the predominantly secular professionals in the Netherlands, to recognize and address religious themes.
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Jamalludin, Mohd Riduan, Zawati Harun, Hatijah Basri, Muhamad Zaini Yunos, and Muhamad Fikri Shohur. "Performance Studies of Polysulfone-Based Membrane: Effect of Silica Morphology." Applied Mechanics and Materials 372 (August 2013): 8–12. http://dx.doi.org/10.4028/www.scientific.net/amm.372.8.

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In the present work, polysulfone (PSf) ultrafiltration membranes were prepared by solution casting. The effects of rice husk silica (RHS) on the surface properties of the PSf/Polyethylene glycol (PEG) membrane were observed and investigated. Characterizations were conducted to determine the membrane cross-section area and RHS distribution. The structure of RHS and morphology of membrane were analyzed by using X-ray diffractometer (XRD) and scanning electron microscope (SEM). XRD pattern showed that the amorphous silica was produced from rice husk ash (RHA). The analysis of SEM indicates that the addition of RHS obviously changed the microstructure of the membrane especially at top layer and sub layer.
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4

Xia, Senmao, Yu Xiong, Min Zhang, James Cornford, Yipeng Liu, Ming K. Lim, Dongmei Cao, and Fengwen Chen. "Reducing the resource acquisition costs for returnee entrepreneurs: role of Chinese national science parks." International Journal of Entrepreneurial Behavior & Research 26, no. 7 (July 30, 2020): 1627–57. http://dx.doi.org/10.1108/ijebr-04-2019-0202.

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PurposeThe purpose of this paper is to empirically explore the mechanisms through which Chinese National Science Parks' (NSPs) services facilitate returnee entrepreneurs' (REs) acquisition of resources for their new ventures. Resource acquisition is crucial for new ventures, but it inevitably leads to significant costs increase. Although the NSPs offer various services to REs to reduce these costs, they still struggle to find the right mix of services.Design/methodology/approachFrom the transaction cost's perspective, an exploratory multiple-case study was conducted with data collected from six NSPs in China.FindingsThe results reveal that four types of NSP services (mentoring and training, social event, promotion of REs and accreditation of resource holders (RHs)) have both individual and joint effects on reducing REs' resource acquisition costs. Specifically, the “accreditation of RHs” service directly helps REs reduce search costs. The combination of “accreditation of RHs”, “promotion of REs” and “social event” services help REs and RHs to establish guanxi. Further, guanxi, working along with the “mentoring and training” service, helps REs to reduce contracting, monitoring and enforcement costs.Originality/valueThis study is among the first to explore the matching mechanisms between science parks’ services and entrepreneurs' cost reduction. This helps reconcile the inconsistent findings on science parks' effect by explaining why some NSPs are able to provide strong support to REs while others are less successful. In addition, the findings are useful for NSPs to develop the right mix of tailored services for REs. Finally, REs will find this study useful to evaluate which NSP is a more suitable location for their new ventures.
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5

HENRIQUES, Gilberto Simeone, and Silvia Maria Franciscato COZZOLINO. "Determination of metallothionein levels in tissues of young rats fed zinc-enriched diets." Revista de Nutrição 14, no. 3 (December 2001): 163–69. http://dx.doi.org/10.1590/s1415-52732001000300001.

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The objective of this work was to quantify metallothioneins (MT's) in tissues of rats fed different concentrations of zinc, in order to observe the animal response to the metal in relation to different types of diets, and to assess the nutritional status relating to zinc in the diets. Thirty-two Wistar newly-weaned male rats were distributed into four experimental groups and housed in individual cages. They had free access to water and diet containing different zinc concentrations, named RC (AIN 93-like diet), RH (customary diet of the university restaurant), both non-supplemented, and RCS and RHS, supplemented. After four weeks, the animals were killed and liver, kidneys, femurs and testes were isolated to determine metallothionein levels by a Cd/Hb affinity assay. Zinc content was determined by Flame Atomic Absorption Spectroscopy (FAAS). The results showed that zinc supplementation produced no change in the tissue metallothionein profile in the doses under analysis. The highest metallothionein mean concentration was found in the liver - 36.21 ± 0.88 µg/g (mean for RC-RCS groups), and 28.92 ± 5.32 µg/g (mean for RH-RHS groups). Metallothionein concentrations in testes were quite high, considering the small volume of the organ - 19.29 ± 0.54 µg/g (mean for RC-RCS groups), and 17.22 ± 1.07 µg/g (mean for RH-RHS groups). Significant increases in zinc concentration were observed in the liver of young supplemented rats - 38.94 ± 3.43 µg/g of tissue for RCS, and 42.83 ± 2.78 µg/g of tissue for RHS, and in the femurs - 140.04 ± 6.03 µg/g of tissue for RCS, and 86.57 ± 6.95 µg/g of tissue for RHS. The different carrying zinc food matrices caused no change in the adaptive response to metallothionein metabolism, and the lack of responsiveness towards metallothionein synthesis did not invalidate the results of tissue zinc concentration parameters, which suggest different degrees for zinc bioavailability.
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6

Phosee, Jirapa, Jatuporn Wittayakun, and Nitinat Suppakarn. "Effect of Acrylic Acid Treated Rice Husk Silica on Properties of Poly (butylene adipate-co-terephthalate) (PBAT) Composites." Advanced Materials Research 410 (November 2011): 81–85. http://dx.doi.org/10.4028/www.scientific.net/amr.410.81.

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In this work, rice husk silica (RHS), obtained from rice husk waste, was used as a reinforcing filler for preparing PBAT composites. In order to facilitate interfacial adhesion between PBAT matrix and RHS filler, the RHS surface was treated with acrylic acid (AA) at a reaction temperature of 140°C. The RHS to AA weight ratio was fixed while the reaction times were varied between 3-24 h. TGA results and FTIR spectra indicated the appearance of AA molecules on RHS surface. Untreated RHS (U-RHS) and AA treated RHS (AA-RHS) were used to produce PBAT composites. The filler content was 30 wt%. Tensile properties and impact strength of AA-RHS/PBAT composites were higher than those of U-RHS/PBAT composite. As revealed by SEM micrographs, AA-RHS was well dispersed in PBAT matrix and the interfacial adhesion between RHS surface and PBAT matrix was improved.
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Phosee, Jirapa, Jatuporn Wittayakun, and Nitinat Suppakarn. "Mechanical Properties and Morphologies of Rice Husk Silica (RHS)/ Poly (butylene adipate-co-terephthalate) (PBAT) Composites: Effect of Silane Coupling Agent." Advanced Materials Research 123-125 (August 2010): 141–44. http://dx.doi.org/10.4028/www.scientific.net/amr.123-125.141.

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In this work, rice husk silica (RHS), obtained from rice husk waste, was used as a reinforcing filler for preparing PBAT composites. The RHS surface was modified using a silane coupling agent, i.e. γ-methacryloxypropyltrimethoxysilane (MPS), in order to facilitate interfacial adhesion between PBAT matrix and RHS filler. The contents of MPS were varied between 0.5 - 5.0 % based on weight of RHS. FTIR spectra indicated the appearance of MPS molecules on RHS surface. Untreated RHS and MPS treated RHS were used to produced RHS/PBAT composites containing 30%wt RHS. The results showed that mechanical properties of the PBAT composites can be enhanced by treating RHS surface with 2 %wt MPS.
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8

Cho, In Hwan, Min Seong Kim, Nam Hun Heo, and So Young Kim. "Birth-related retinal hemorrhages: The Soonchunhyang University Cheonan Hospital universal newborn eye screening (SUCH-NES) study." PLOS ONE 16, no. 11 (November 9, 2021): e0259378. http://dx.doi.org/10.1371/journal.pone.0259378.

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Purpose To report the prevalence, related factors, and characteristics of birth-related retinal hemorrhages (RHs) according to their severity in healthy newborns using a telemedicine network and wide-field digital retinal imaging (WFDRI). Methods Newborns who underwent WFDRI at 61 obstetrics/gynecology hospitals between January 2017 and December 2019 were enrolled. Demographics and related factors were compared among newborns with and without RHs. The newborns’ eyes were divided into the minimal, mild, moderate, and severe groups according to the number of RHs, and characteristics like bilaterality, laterality, involved retinal layer, involved zone, macular and/or optic nerve (ON) involvement were compared. Results Among 56247 newborns, 13026 had birth-related RHs (23.2%). Normal spontaneous vaginal delivery (NSVD) showed the highest association with RHs (odds ratio, 19.774; 95% confidence interval, 18.277–21.393; P < 0.001) on multivariate analysis. Bilateral RHs (8414/13026; 64.59%) were more common than unilateral RHs (4612/13026; 35.41%); however, unilateral RHs (2383/4217; 56.51%) were more common than bilateral RHs (1834/4217; 43.49%) in the minimal group. RHs showed no laterality differences between the two eyes (P = 0.493). Most RHs were intraretinal (18678/21440; 87.12%), and 2328 (31.65%) eyes with preretinal hemorrhage were observed in the severe group. Zone I RHs were common in the minimal (7072/7090; 99.75%), mild (4953/4960; 99.86%), and moderate (2013/2035; 98.92%) groups; zone I and II RHs were common in the severe group (4843/7355; 65.85%); and RHs in zone III were rare (7/21440; 0.03%). Most RHs showed no macular and/or ON involvement in the minimal and mild group; however, this was common in the severe group (7111/7355; 96.68%). Conclusions Birth-related RHs were common in healthy newborns and were significantly associated with NSVD. RHs were usually bilateral, intraretinal, and distributed posterior to the retina, but severe RHs had unique characteristics. Future long-term and longitudinal studies are required to elucidate the prognosis of severe RHs.
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9

DA SILVA BENACON, MARIA, SUELEN MIRANDA DOS SANTOS,, RAYZA LIMA ARAÚJO, JACKSON PANTOJA-LIMA, PAULO HENRIQUE ROCHA ARIDE, and ADRIANO TEIXEIRA DE OLIVEIRA. "Índices de condición corporal de Matrinxã Brycon Amazonicus del Río Juruá, Amazonas." Revista Colombiana de Ciencia Animal - RECIA 7, no. 1 (January 11, 2015): 44. http://dx.doi.org/10.24188/recia.v7.n1.2015.421.

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Este estudio tuvo como objetivo determinar las relaciones peso-talla (RPT), hepatosomático (RHS), esplenosomática (RES) y viscerosomática (SVR) y el factor de condición relativo (Kn), y las relaciones entre los índices corporales en Brycon amazonicus matrinxã del bajo río Juruá, Amazonas. Un total de 40 ejemplares fueron capturados. Los valores medios y desviación estándar fueron: longitud total (32,10 ± 2,22 cm), peso (765,00 ± 102,12 g), hígado (10,73 ± 1,79 g), bazo (0,33 ± 0,05 g), vísceras (61,21 ± 16,95 g), RHS (1,42 ± 0,27%), RES (0,04 ± 0,01 %), la RVS (8,03 ± 1,99 %) y Kn (1,12 ± 0,01). La matrinxã presentó un crecimiento alométrico negativo, mostrando una mayor ganancia de longitud total que de peso. Fue observada una relación (p< 0,05) entre el peso y el hígado (p=0,015), entre CT y vísceras (0,018), entre peso y vísceras (p= 0,018), y entre CT e hígado (0,038). Se observo una correlación negativa entre CT y RVS (p= 0,040), entre bazo y RVS (p= 0,001) y entre vísceras y RHS (p= 0,020). Se determionó correlación positiva entre Kn y RHS (p= 0,024) y entre bazo e hígado (p= 0,016). Con el presente trabajo es posible determinar el peso de órganos vitales a partir de medidas simples como La longitud total y el peso corpóreo, lo que proporciona el permite inferir la condición de salud de las poblaciones de matrinxã sin que se tenga que sacrificar especímenes para conocerla.
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10

Bernardo, Werica P., Renata T. Souza, André G. Costa-Martins, Eden R. Ferreira, Renato A. Mortara, Marta M. G. Teixeira, José Luis Ramirez, and José F. Da Silveira. "Genomic Organization and Generation of Genetic Variability in the RHS (Retrotransposon Hot Spot) Protein Multigene Family in Trypanosoma cruzi." Genes 11, no. 9 (September 17, 2020): 1085. http://dx.doi.org/10.3390/genes11091085.

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Retrotransposon Hot Spot (RHS) is the most abundant gene family in Trypanosoma cruzi, with unknown function in this parasite. The aim of this work was to shed light on the organization and expression of RHS in T. cruzi. The diversity of the RHS protein family in T. cruzi was demonstrated by phylogenetic and recombination analyses. Transcribed sequences carrying the RHS domain were classified into ten distinct groups of monophyletic origin. We identified numerous recombination events among the RHS and traced the origins of the donors and target sequences. The transcribed RHS genes have a mosaic structure that may contain fragments of different RHS inserted in the target sequence. About 30% of RHS sequences are located in the subtelomere, a region very susceptible to recombination. The evolution of the RHS family has been marked by many events, including gene duplication by unequal mitotic crossing-over, homologous, as well as ectopic recombination, and gene conversion. The expression of RHS was analyzed by immunofluorescence and immunoblotting using anti-RHS antibodies. RHS proteins are evenly distributed in the nuclear region of T. cruzi replicative forms (amastigote and epimastigote), suggesting that they could be involved in the control of the chromatin structure and gene expression, as has been proposed for T. brucei.
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11

Uchiba, Mitsuhiro, Kenji Okajima, Kazunori Murakami, Masayoshi Johno, Mitsunobu Mohri, Hiroaki Okabe, and Kiyoshi Takatsuki. "rhs-TM prevents ET-induced increase in pulmonary vascular permeability through protein C activation." American Journal of Physiology-Lung Cellular and Molecular Physiology 273, no. 4 (October 1, 1997): L889—L894. http://dx.doi.org/10.1152/ajplung.1997.273.4.l889.

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We have previously demonstrated that recombinant human soluble (rhs) thrombomodulin (TM) inhibits the endotoxin (ET)-induced increase in pulmonary vascular permeability by inhibiting leukocyte activation. In the present study, we examined whether rhs-TM could inhibit the ET-induced increase in pulmonary vascular permeability in rats by activating protein C. rhs-TM did not inhibit ET-induced increases in pulmonary vascular permeability when its protein C activation ability was selectively inhibited by a monoclonal antibody (MAb) against rhs-TM (MAb R5G12). Histological examination revealed that neutrophil infiltration in lung tissues after ET administration was significantly reduced by rhs-TM, but infiltration was not reduced by MAb R5G12-pretreated rhs-TM. ET-induced intravascular coagulation was prevented by rhs-TM and by MAb R5G12-pretreated rhs-TM. However, ET-induced coagulation was not prevented by rhs-TM that had been treated with MAb F2H5, which cannot bind thrombin or activate protein C. These observations strongly suggest that rhs-TM prevents ET-induced pulmonary vascular injury by inhibiting pulmonary accumulation of leukocytes through thrombin binding and the subsequent protein C activation and may prevent ET-induced intravascular coagulation through thrombin binding.
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Aritomi, Masaharu, Naoko Watanabe, Rika Ohishi, Komakazu Gomi, Takao Kiyota, Shuji Yamamoto, Torao Ishida, and Ikuro Maruyama. "Recombinant Human Soluble Thrombomodulin Delivers Bounded Thrombin to Antithrombin III: Thrombomodulin Associates with Free Thrombin and Is Recycled to Activate Protein C." Thrombosis and Haemostasis 70, no. 03 (1993): 418–22. http://dx.doi.org/10.1055/s-0038-1649597.

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SummaryRecombinant human soluble thrombomodulin (rhs-TM), having no transmembrane domain or chondroitin sulfate, was expressed in Chinese hamster ovary cells. Interactions between rhs-TM, thrombin (Th), protein C (PC) and antithrombin III (ATIII) were studied. Equilibrium between rhs-TM and Th had no detectable time lag in clotting inhibition (K d = 26 nM) or PC activation (K d = 22 nM), while ATIII inhibited Th at a bimolecular rate constant = 5,200 M-1s-1 (K d <0.2 nM). A mixture of ATIII, Th and rhs-TM showed that ATIII reacted with Th slower than rhs-TM, whose presence did not affect the reaction between ATIII and Th. In a mixture of rhs-TM, ATIII and PC, the repeated addition of Th caused the repeated activation of PC; which was consistent with the Simulation based on the assumption that rhs-TM is recycled as a Th cofactor. From these results, we concluded that upon inhibition of the rhs-TM-Th complex by ATIII, rhs-TM is released to recombine with free Th and begins to activate PC, while the Th-ATIII complex does not affect rhs-TM-Th equilibrium.
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13

Yahya, Sufiah Mohamad, A. Azmi, Sufizar Ahmad, and Hariati Taib. "Characterisation of Hand-Cast Polysiloxane-Silica Sheet Composite." Advanced Materials Research 893 (February 2014): 250–53. http://dx.doi.org/10.4028/www.scientific.net/amr.893.250.

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The study investigates the effects of various contents of rice husk silica (RHS) on mechanical properties of polysiloxane (POS) sheet composite. The polysiloxane sheet composites filled with 5wt%, 10wt%, 15wt% and 20wt% of RHS were fabricated using casting technique at room temperature. The polysiloxane sheet reinforced RHS (POS-RHS) composites were characterised using thermogravimetry analysis (TGA), Fourier Transformation Infrared Spectroscopy (FTIR) and tensile test to determine the thermal and mechanical properties. It was found that the RHS as filler in polysiloxane is improvement in mechanical properties and the curve degradation of POS and POS-RHS are similarly. By using FTIR was shown the affect of Si and O bonding from RHS as filler.
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Taoka, Yuji, Mitsuhiro Uchiba, Masayoshi Johno, and Kenji Okajima. "Neuroprotection by Recombinant Thrombomodulin." Thrombosis and Haemostasis 83, no. 03 (2000): 462–68. http://dx.doi.org/10.1055/s-0037-1613837.

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SummaryWe examined whether recombinant human soluble thrombomodulin (rhs-TM) reduces compression trauma-induced spinal cord injury through protein C activation in rats. Administration of rhs-TM, either before or after the induction of spinal cord injury (SCI), markedly reduced the resulting motor disturbances. However, neither rhs-TM pretreated with an anti-rhs-TM monoclonal antibody (MAb) F2H5, which inhibits thrombin binding to rhs-TM, nor those pretreated with MAb R5G12, which selectively inhibits protein C activation by rhsTM, prevented the motor disturbances. Intramedullary hemorrhages, observed 24 h after trauma, were significantly reduced in animals given rhs-TM. The increase in the tissue levels of tumor necrosis factor-α (TNF-α), TNF-α mRNA expression, and the accumulation of leukocytes in the damaged segment of the spinal cord were significantly inhibited in animals receiving rhs-TM, but these effects were not observed following administration of rhs-TM pretreated with MAb R5G12 or MAb F2H5. Leukocytopenia and activated protein C all produced effects similar to those of rhs-TM.These findings suggest that rhs-TM prevents compression traumainduced SCI by inhibiting leukocyte accumulation by reducing the expression of TNF-α mRNA and such therapeutic effects of rhs-TM could be dependent on its protein C activation capacity. Findings further suggest that thrombomodulin can be implicated not only in the coagulation system but in regulation of the inflammatory response.
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Salim, Zainathul Akhmar Salim Abdul, Aziz Hassan, Hanafi Ismail, and Nor Hafizah Che Ismail. "Tensile Properties and Dynamic Mechanical Behaviour of Natural Rubber Compound Filled with Rice Husk Silica Produced via Solvent-Thermal Extraction Method." Materials Science Forum 947 (March 2019): 195–99. http://dx.doi.org/10.4028/www.scientific.net/msf.947.195.

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This study highlighted the effect of incorporation of rice husk silica (RHS) on the tensile properties and dynamic mechanical behaviour of natural rubber (NR) compounds. High purity RHS was synthesised by solvent-thermal extraction method, which was inspired by TAPPI T204 cm-97 and TAPPI T264 cm-97 standards with some modifications. The extraction method had successfully produced RHS with 99.9% of silica content and surface area of 234.25 m2/g. The incorporation of RHS in NR showed increment in tensile properties compared to unfilled NR. Further improvement was recorded by surface modification of RHS with 1 wt. % bis (triethoxysilylpropyl) tetrasulfide (TESPT). The modification of RHS with TESPT increased the rubber-filler interaction between RHS and NR matrix, hence enhancing the strength-related properties. The modified RHS-NR also recorded highest storage modulus, and the presence of RHS in the NR compound had slightly shifted the glass transition temperature (Tg) to a higher value. This confirmed that the strong rubber-filler interaction had increased the rigidity of the compounds and restricted the mobility of the rubber chains.
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Hoang-Tung, Nguyen, Hoang Thuy Linh, Hoang Van Cuong, Phan Le Binh, Shinichi Takeda, and Hironori Kato. "Ride-Hailing Service Adoption and Local Context in Motorcycle-Based Societies: Case Study in Hanoi, Vietnam." Sustainability 14, no. 2 (January 10, 2022): 728. http://dx.doi.org/10.3390/su14020728.

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The ride-hailing service (RHS) has emerged as a major form of daily travel in many Southeast Asian cities where motorcycles are extensively used. This study aims to analyze the local context in motorcycle-based societies, which may affect the establishment of travelers’ choice set after the appearance of RHSs. In particular, it empirically compares three types of choice-set structures in the context of urban travel mode choice by estimating standard logit and nested logit models to test six hypotheses on the associations of RHS adoption with its determinants. Revealed preference data of 449 trips from both RHS users and non-RHS users were collected through a face-to-face interview-based questionnaire survey in Hanoi, Vietnam, in December 2020. The results of model estimations revealed: (1) a substitutional effect for two-wheelers but not for four-wheelers, (2) a significant positive influence of car ownership on car RHS adoption but not on motorcycle RHS adoption, (3) significantly high sensitivity to travel time of motorcycle RHS but not of car RHS, (4) a significant negative effect of traffic congestion on car RHS adoption but an insignificant one on motorcycle RHS adoption, and (5) a significant positive association of an individual’s experience in using a smartphone with car RHSs but insignificant association with motorcycle RHSs. Our findings suggest that transportation policies of RHS motorcycles should be different from those of RHS cars because of the heterogeneity in travel behaviors of RHS users between them. They also indicate that the transition from motorcycles to cars as well as the difference in service availability among different types of RHSs should be incorporated into the development of transportation policies in Southeast Asian cities.
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Hill, C. W., G. Feulner, M. S. Brody, S. Zhao, A. B. Sadosky, and C. H. Sandt. "Correlation of Rhs elements with Escherichia coli population structure." Genetics 141, no. 1 (September 1, 1995): 15–24. http://dx.doi.org/10.1093/genetics/141.1.15.

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Abstract The Rhs family of composite genetic elements was assessed for variation among independent Escherichia coli strains of the ECOR reference collection. The location and content of the RhsA-B-C-F subfamily correlates highly with the clonal structure of the ECOR collection. This correlation exists at several levels: the presence of Rhs core homology in the strain, the location of the Rhs elements present, and the identity of the Rhs core-extensions associated with each element. A provocative finding was that an identical 1518-bp segment, covering core-extension-b1 and its associated downstream open reading frame, is present in two distinct clonal groups, but in association with different Rhs elements. The sequence identity of this segment when contrasted with the divergence of other chromosomal segments suggests that shuffling of Rhs core extensions has been a relatively recent variation. Nevertheless the copies of core-extension-b1 were placed within the respective Rhs elements before the emergence of the clonal groups. In the course of this analysis, two new Rhs elements absent from E. coli K-12 were discovered: RhsF, a fourth member of the RhsA-B-C-F subfamily, and RhsG, the prototype of a third Rhs subfamily.
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Mashiri, F. R., and X. L. Zhao. "Fatigue tests and design of welded thin-walled RHS–RHS and RHS–angle cross-beam connections under cyclic bending." Thin-Walled Structures 48, no. 2 (February 2010): 159–68. http://dx.doi.org/10.1016/j.tws.2009.07.006.

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Yoon, Eun Sun, and Soo Hyun Park. "Associations between Relative Handgrip Strength and Incidence of Type 2 Diabetes Mellitus in Middle-aged and Older adults: Finding from the Korean Genome and Epidemiology Study." Exercise Science 29, no. 4 (November 30, 2020): 377–84. http://dx.doi.org/10.15857/ksep.2020.29.4.377.

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PURPOSE: We investigated whether relative handgrip strength (RHS) and change in handgrip strength predicted Type 2 DM incidence in middle-aged and older adults.METHODS: Total of 29,098 participants (8,609 men and 20,489 women) aged 40-69 who were free of diabetes at the baseline examination drawn from the Korean Genome and Epidemiology Study-Urban Health Examinees cohort (KoGES-HEXA), a large prospective population-based study. RHS was assessed with a dynamometer and divided by body mass index. Diabetes was defined as selfreported physician-diagnosed diabetes, use of anti-diabetic medications or measured fasting glucose ≥126 mg/dl, or glycated hemoglobin (HbA1C) ≥6.5%. Cox proportional hazard regression analysis was used to estimate the hazard ratio (HRs) and 95% confidence intervals (CIs) of Diabetes incidences according to baseline RHS levels and RHS changes.RESULTS: During a mean follow-up period of 4 years (49.8±13.3 month), 1,167 (4.0%) participants developed diabetes. Compared with the high RHS group, higher risk of diabetes incidence was observed in low RHS group (men HR=1.28, 95% CI 1.06-1.55, women HR=1.32, 95% CI 1.12-1.54) after adjusted for age, triglyceride, cigarette smoking, alcohol consumption, marriage, income, education hypertension, family history of diabetes, fasting glucose, regular exercise. In addition, compared with the sustained high RHS group, sustained low RHS group showed an increased risk of diabetes incidence (men HR=1.60, 95% CI 1.28-2.00, women HR=1.85, 95% CI 1.52-2.24) after adjustment. However, the risk was not statistically significant in increased RHS group (men HR=0.98, 95% CI 0.73-1.31, women HR=1.11, 95% CI 0.85-1.43).CONCLUSIONS: The present findings indicate that RHS is independently associated with the risk of incident diabetes in middle and older adults. RHS measurement may be useful to identify individuals at increased risk for diabetes incidence. Maintaining a high level of RHS is important strategies for diabetes prevention among adults.
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Ovalle B., Pilar, Manuel Azócar M., Carolina Nicklas D., Milena Villarroel C., and Jorge Morales V. "Reacciones de hipersensibilidad asociadas al uso de asparaginasa en niños con leucemia linfoblástica aguda." Andes Pediatrica 92, no. 2 (May 4, 2021): 182. http://dx.doi.org/10.32641/andespediatr.v92i2.2151.

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El tratamiento de la leucemia linfoblástica aguda (LLA) incluye el uso de asparaginasa (ASP), medicamento asociado a reacciones de hipersensibilidad (RHS) que requieren discontinuar su uso.Objetivo: Determinar la incidencia de RHS asociadas a ASP que requieran discontinuar su uso y describirlas, y verificar si hay asociación entre incidencia de RHS y protocolos o sobrevida.Pacientes y Método: Estudio retrospectivo. Se revisaron los registros clínicos de todos los pacientes (1-15 años) diagnosticados de LLA entre enero de 2010 y diciembre de 2015 en el Hospital Luis Calvo Mackenna. Se determinó incidencia de RHS a ASP, se clasificaron según score de gravedad CTCAE v5.0, se analizó riesgo relativo de RHS con test de Fisher y sobrevida con estimador Kaplan-Meier.Resultados: Se recopilaron 110 pacientes. Durante el primer tratamiento (ALL-IC-BFM), la incidencia de RHS a L-ASP fue 55%, cambiándose a PEG-ASP como segunda línea. De estos, 44% presentó RHS, debiendo discontinuarse ASP definitivamente en 25% de los pacientes. De todas las RHS, 77% fueron anafilácticas (CTCAE 3-5). Los pacientes en protocolo IB aumentado tuvieron mayor riesgo de no completar tratamiento con ASP, RR 3,81 (IC 95%, 1,98-7,31, p = 0,0001). Los pacientes sin RHS en ALL-IC-BFM presentaron menor riesgo de recaer, HR 0,29 (IC 95%, 0,14-0,62, p = 0,0013). Considerando todos los tratamientos (ALL-IC-BFM y recaídas), los que completaron tratamiento con ASP tuvieron mayor sobrevida global, HR 0,20 (IC 95%, 0,07-0,57, p = 0,0026).Conclusiones: Las RHS a ASP que requieren suspensión de tratamiento son frecuentes en niños con LLA, siendo mayormente reacciones anafilácticas graves. Este estudio sugiere mejor pronóstico en pacientes sin RHS a ASP.
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Hong, Yong-Han, Chung-Chih Tseng, Desy Setyoningrum, Zu-Po Yang, Maftuch, and Shao-Yang Hu. "Rice Husk Silica Enhances Innate Immune in Zebrafish (Danio rerio) and Improves Resistance to Aeromonas hydrophila and Streptococcus iniae Infection." Sustainability 11, no. 22 (November 19, 2019): 6504. http://dx.doi.org/10.3390/su11226504.

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Rice husk (RH) contains abundant silica such that RH silica (RHS) may be useful for possible industrial exploitation. Here, amorphous silica nanoparticles with multiple pore structures were acquired from RH by simple thermochemical processes. RHS antimicrobial activity and effects on zebrafish innate immunity against pathogen infections were evaluated. A toxicity assay showed that zebrafish exposed to an RHS dose lower than 200 μg/mL did not exhibit damage to zebrafish embryonic development or juvenile survival. RHS showed a wide spectrum of bacteriostatic activity against a variety of pathogens including antibiotic-resistant pathogens, implying its potential application as an antimicrobial agent in diverse industries. Fish exposed to 20 or 200 μg/mL RHS exhibited significantly increased mRNA expression of immune-related genes, including IL-1β, IL-6, IL-15, TNF-α, COX-2a, TLR-4a, lysozyme, and complement C3b. RHS-treated zebrafish exhibited a higher cumulative survival compared to that in control fish after infecting with Aeromonas hydrophila and Streptococcus iniae. The present results showed that a safe RHS dose enhanced innate immunity against infections without toxic effects in healthy fish, suggesting that RHS may be developed as an immunostimulant for improving health status in aquaculture.
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Smith, Andy. "RHS Encyclopedia of Conifers." Arboricultural Journal 34, no. 4 (December 2012): 238–39. http://dx.doi.org/10.1080/03071375.2012.747712.

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Fan, YuJing, and Jeffrey A. Packer. "RHS-to-RHS axially loaded X-connections near an open chord end." Canadian Journal of Civil Engineering 44, no. 11 (November 2017): 881–92. http://dx.doi.org/10.1139/cjce-2017-0148.

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In all truss-type welded hollow structural section connection design procedures, the chord member is assumed continuous on both sides of the branch. New limits of applicability have recently been advocated, which specify minimum end distances from an open chord end to achieve the full connection strength. To investigate their suitability for rectangular hollow section (RHS) connections, an experimental program consisting of 12 RHS-to-RHS X-connections subject to branch axial compression was undertaken. For connections near a chord end, a modified yield line mechanism controlled. A proposed analytical model is derived, and by evaluating against the experimental results, is shown to accurately predict the yield loads. An EN 1993-1-8 amendment, transcribed from circular hollow section connections, is deemed excessively conservative, and a closed-form solution for the end distance, presented herein, is recommended for use with RHS connections. Alternatively, providing a cap plate is determined to be an effective stiffening method.
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Kukhar, Volodymyr, Yurii Sahirov, Vadym Hornostai, Oleg Markov, and Mykyta Nahnibeda. "FEM simulation of bending and torsion tests of similar size RHS but of the different production options." E3S Web of Conferences 234 (2021): 00079. http://dx.doi.org/10.1051/e3sconf/202123400079.

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The paper implements a method for analyzing the stress-strain state of rectangular hollow sections (RHS) by finite-element modeling (FEM) of tests for three-point bending and torsion. Design schemes, 3-D solid-state and deformable models have been developed using the automated analysis and CAD/CAE system software, made it possible to obtain equivalent stress distributions and displacements in models. A simulation of tests for RHS with a cross section of 40 mm × 50 mm, manufactured in two ways, was carried out: (a) by direct-forming of galvanized steel strips on roll-forming mill in a semi-closed section with a longitudinal gap of 0.5 mm between the edges formed on a 40 mm web (DF-RHS); (b) similar direct-forming to the closed section and next welding the edges to a longitudinal weld along the web middle of 50 mm (DFW-RHS). RHS with various wall thicknesses (t = 1.93 mm, 1.84 mm and 0.7 mm) was investigated, given the design features that depend on the manufacturing processes of structural sections. It was found DFW-RHS is stiffer by at least 50% compared to DF-RHS, which allows to savings the metal by reducing the RHS wall thickness by 62% while maintaining the same stiffness and ensuring high strength of structural section.
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Abdul Salim, Zainathul Akhmar, Aziz Hassan, and Hanafi Ismail. "The effect of high purity rice husk silica synthesised using solvent-thermal extraction method on the properties of natural rubber compounds." BioResources 13, no. 3 (July 27, 2018): 6936–51. http://dx.doi.org/10.15376/biores.13.3.6936-6951.

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This work highlights the synthesis of high purity silica from rice husks and the effect of rice husk silica (RHS) loading on the mechanical, physical, and thermal properties of natural rubber (NR) compounds. The RHS was synthesised using the solvent-thermal extraction method, which was adopted from TAPPI T204 (2007) and TAPPI T264 (1997) standards with some modifications. The treatment successfully produced high purity RHS particles, with 99.9% SiO2 content between 100 to 300 nm in size. The high purity RHS was then incorporated in NR compounds at 2, 4, 6, 8, and 10 parts per hundred rubber (phr). Even without any surface modification, the high purity RHS-filled NR compounds showed tremendous improvements in strength-related properties at the optimum loading of 4 phr. In addition, the thermal stability of the NR compounds was remarkably improved with the addition of RHS.
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Martínez Cordellat, I., R. Gonzalez Mazario, M. De la Rubia Navarro, C. Pávez Perales, S. Leal Rodriguez, J. Ivorra Cortés, I. Chalmeta Verdejo, et al. "AB1048 RHUPUS SYNDROME IN A TERTIARY HOSPITAL." Annals of the Rheumatic Diseases 79, Suppl 1 (June 2020): 1815.1–1815. http://dx.doi.org/10.1136/annrheumdis-2020-eular.3468.

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Background:Rhupus syndrome (RhS) is a rare combination of rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). Different studies describe RhS cases that begin with erosive arthritis and the presence of rheumatoid factor (RF) and/or anti CCP and then the SLE symptoms.Objectives:Despite the fact that RhS shows a low prevalence, it would be useful to know clinical characteristics of RhS patients since their therapy and outcome differ from those having RA or SLE alone.Methods:Retrospective study with systematic revision of electronic clinical records of RhS patients was performed. Demographic, clinical and immunological data were collected.Results:Eight RhS patients were included (all fulfilled SLICC 2012 criteria for SLE and ACR 2010 for RA). Mean age was 67.3 (45-84) years (7 were female).In 3 cases RA was the first diagnosis with a mean evolution of 4.5 years until SLE diagnosis. In contrast, in 5 cases SLE was the first diagnosis with a mean evolution of 7.2 years until RA diagnosis. Photosensitivity and arthritis were the predominant clinical manifestations. One patient presents pericarditis and other case showed rheumatoid nodules in elbows. Renal, pulmonary or neurological affection was no reported.4 patients were under biological/JAK inhibitors therapies (2 abatacept, 1 rituximab and 1 baricitinib) with favorable response of treatment.Conclusion:In contrast to other series, only the 37.5% of our RhS cases begins with polyarticular seropositive arthritis. The 62.5% started with SLE symptoms as haematological alterations, cutaneous and serological manifestation, and showed longer progression to have polyarticular affection. Thus, RhS diagnosis is earlier in patients that begin with RA symptoms. 4 RhS patients were refractory to DMARd treatments, where biological/JAK inhibitors therapies are needed.Disclosure of Interests:None declared
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Bringaud, Frédéric, Nicolas Biteau, Sara E. Melville, Stéphanie Hez, Najib M. El-Sayed, Vanessa Leech, Matthew Berriman, Neil Hall, John E. Donelson, and Théo Baltz. "A New, Expressed Multigene Family Containing a Hot Spot for Insertion of Retroelements Is Associated with Polymorphic Subtelomeric Regions of Trypanosoma brucei." Eukaryotic Cell 1, no. 1 (February 2002): 137–51. http://dx.doi.org/10.1128/ec.1.1.137-151.2002.

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ABSTRACT We describe a novel gene family that forms clusters in subtelomeric regions of Trypanosoma brucei chromosomes and partially accounts for the observed clustering of retrotransposons. The ingi and ribosomal inserted mobile element (RIME) non-LTR retrotransposons share 250 bp at both extremities and are the most abundant putatively mobile elements, with about 500 copies per haploid genome. From cDNA clones and subsequently in the T. brucei genomic DNA databases, we identified 52 homologous gene and pseudogene sequences, 16 of which contain a RIME and/or ingi retrotransposon inserted at exactly the same relative position. Here these genes are called the RHS family, for retrotransposon hot spot. Comparison of the protein sequences encoded by RHS genes (21 copies) and pseudogenes (24 copies) revealed a conserved central region containing an ATP/GTP-binding motif and the RIME/ingi insertion site. The RHS proteins share between 13 and 96% identity, and six subfamilies, RHS1 to RHS6, can be defined on the basis of their divergent C-terminal domains. Immunofluorescence and Western blot analyses using RHS subfamily-specific immune sera show that RHS proteins are constitutively expressed and occur mainly in the nucleus. Analysis of Genome Survey Sequence databases indicated that the Trypanosoma brucei diploid genome contains about 280 RHS (pseudo)-genes. Among the 52 identified RHS (pseudo)genes, 48 copies are in three RHS clusters located in subtelomeric regions of chromosomes Ia and II and adjacent to the active bloodstream form expression site in T. brucei strain TREU927/4 GUTat10.1. RHS genes comprise the remaining sequence of the size-polymorphic “repetitive region” described for T. brucei chromosome I, and a homologous gene family is present in the Trypanosoma cruzi genome.
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Rongchapo, Wina, Onsulang Sophiphun, Kamolwan Rintramee, Sanchai Prayoonpokarach, and Jatuporn Wittayakun. "Paraquat adsorption on porous materials synthesized from rice husk silica." Water Science and Technology 68, no. 4 (August 1, 2013): 863–69. http://dx.doi.org/10.2166/wst.2013.311.

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The goal of this work was to utilize rice husk silica (RHS) and porous materials synthesized with RHS, including mesoporous material (MCM-41) and microporous materials (zeolite NaY and NaBEA), for adsorption of herbicide paraquat. The adsorption occurred although cation exchange and the capacity decreased in the following order: NaY &gt; NaBEA &gt; MCM-41 &gt; RHS, consistent with the amount of Al. The adsorption on all adsorbents fitted well with the Langmuir model and the maximum adsorption capacity of 185.2 mg/g-adsorbent was obtained on NaY. In addition, blue dye in commercial grade paraquat did not interfere with paraquat adsorption. Although MCM-41 was the most efficient adsorbent for the blue dye, RHS was favorable in terms of production cost. A mixture of NaY and RHS is recommended for simultaneous adsorption of paraquat and blue dye.
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Aydoğdu, İmran, Enes Ataç, Ziya Saltürk, Yavuz Atar, Erdi Özdemir, Yavuz Uyar, Ahmet Arslanoğlu, and Güler Berkiten. "Pediatric Ramsay Hunt Syndrome: Analysis of Three Cases." Case Reports in Otolaryngology 2015 (2015): 1–4. http://dx.doi.org/10.1155/2015/971249.

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Ramsay Hunt syndrome (RHS) is a disorder characterized by herpetic eruptions on the auricle, facial paralysis, and vestibulocochlear dysfunction and is attributed to varicella zoster virus (VZV) infection in the geniculate ganglion. Although it is a common cause of acute peripheral facial paralysis, children are not usually affected. The diagnosis is based on history and physical findings. Treatment of RHS uses a combination of high-dose corticosteroids and acyclovir. This paper presents three cases diagnosed as RHS in the pediatric age group in association with the literature review. The aim of this paper is to emphasize the importance of careful examination and early initiation of therapy in suspected cases of RHS.
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30

Madoui, Amar, Alain Leduc, Sylvie Gauthier, and Yves Bergeron. "Spatial pattern analyses of post-fire residual stands in the black spruce boreal forest of western Quebec." International Journal of Wildland Fire 19, no. 8 (2010): 1110. http://dx.doi.org/10.1071/wf10049.

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In this study, we characterised the composition and configuration of post-fire residual habitats belonging to two physiographic zones of the black spruce–moss domain in western Quebec. Thirty-three large fires (2000–52 000 ha) were selected and extracted on classified Landsat satellite imagery. The results show that a minimum of 2% and a maximum of 22% of burned areas escaped fire, with an overall average of 10.4%. The many forest patches that partially or entirely escaped fire formed residual habitats (RHs). It was found that although the area of RHs follows a linear relationship with fire size, their proportion appears relatively constant. Spatial analyses showed that the fires could be separated into two groups depending on the physiographic zones (East-Canadian Shield v. West-Clay Belt Lowlands). Fires in the west zone generate less RHs and appear to be associated with more extreme weather conditions. In most cases there was no association with water or wetlands; in some fires the presence of RHs is associated with the proximity of water bodies. The failure to find an association between RHs and wetlands suggests that this type of environment is part of the fuel. Coniferous woodland with moss appears particularly overrepresented within RHs. Our results suggest that the local and regional physiographic conditions strongly influence the creation of RHs; therefore, it is important to consider those differences when applying ecosystem-based management.
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Sambo, Paolo, Franco Sannazzaro, and Michael R. Evans. "Physical Properties of Ground Fresh Rice Hulls and Sphagnum Peat Used for Greenhouse Root Substrates." HortTechnology 18, no. 3 (January 2008): 384–88. http://dx.doi.org/10.21273/horttech.18.3.384.

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Ground fresh rice (Oryza sativa) hull materials were produced by grinding whole fresh rice hulls and passing the resulting product through a 1-, 2-, 4- or 6-mm-diameter screen to produce a total of four ground rice products (RH1, RH2, RH4, and RH6, respectively). The physical properties and water release characteristics of sphagnum peatmoss (peat) and the four ground rice hull products were evaluated. All of the ground rice hull products had a higher bulk density (Bd) than peat, and as the grind size of the rice hull particle decreased, Bd increased. Peat had a higher total pore space (TPS) than all of the ground rice hull products except for RH6. As grind size decreased, the TPS decreased. Peat had a lower air-filled pore space (AFP) than all of the ground rice hull products and as the grind size of the rice hull products decreased, AFP decreased. Peat had a higher water holding capacity (WHC) than all of the ground rice hull products. Grind sizes RH4 and RH6 had similar WHC, whereas RH1 and RH2 had a higher WHC than RH4 and RH6. Peat, RH4, and RH6 had similar available water content (AVW), whereas RH2 had higher AVW than these materials and RH1 had the highest AVW. However, peat had the lowest AVW and easily available water (EAW) as a percentage of the WHC. The ground rice hull products RH1 and RH2 had the highest AVW and EAW of the components tested. Peat had the highest water content at container capacity. As pressure was increased from 1 to 5 kPa, peat released water more slowly than any of the ground rice hull products. The RH1 and RH2 ground hull products released water at a significantly higher rate than peat, but RH4 and RH6 released the most water over these pressures. For all rice hull products, most water was released between 1 and 2 kPa pressure. The rice hull products RH1 and RH2 had physical properties that were within recommended ranges and were most similar to those of peat.
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Schenkel, Mark T., Jane Finley, and Wade Chumney. "RHS, Inc.: Innovation “Guiding” Agriculture." Entrepreneurship Theory and Practice 36, no. 2 (September 7, 2010): 415–25. http://dx.doi.org/10.1111/j.1540-6520.2010.00408.x.

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Szlendak, J. "Beam-column welded RHS connections." Thin-Walled Structures 12, no. 1 (January 1991): 63–80. http://dx.doi.org/10.1016/0263-8231(91)90027-g.

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Bu, Xiao Ding, Fei Wei, and Jeffrey A. Packer. "Laterally Offset RHS X-Connections." Journal of Structural Engineering 147, no. 1 (January 2021): 04020286. http://dx.doi.org/10.1061/(asce)st.1943-541x.0002864.

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35

Fehervari, Zoltan. "Inflammasome clue to bacterial Rhs." Nature Immunology 13, no. 4 (March 19, 2012): 358. http://dx.doi.org/10.1038/ni.2278.

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Daneshvar, Sara, Min Sun, and Kyle Tousignant. "Stress concentration factors for RHS-to-RHS X-connections near an open chord end." Journal of Constructional Steel Research 175 (December 2020): 106352. http://dx.doi.org/10.1016/j.jcsr.2020.106352.

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37

Cui, Jinlong, and Juncai Sun. "Preparation and application of energy materials from biomass." International Journal of Modern Physics B 32, no. 19 (July 18, 2018): 1840081. http://dx.doi.org/10.1142/s0217979218400817.

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Silicon-based anode materials in recent years has gained tremendous interest due to high theoretical specific capacity for next generation lithium ion battery. Some biomass, such as rice husks (RHs), has contained a lot of inorganic silicon, which are abundant in all the countryside and farmland. Considering that RHs are mainly composed of organic lignin, cellulose, hemicellulose, and inorganic Si compound, they could be used to prepare low-cost electrode materials, such as carbonaceous and silicon-based anode materials. In this work, we will present the synthesis of various anode materials from RHs with prominent performance for lithium ion battery application, such as porous C/SiO[Formula: see text] composites and Al-doped porous carbonized RHs husks composites.
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Balansin Rigon, Roberta, Sabine Kaessmeyer, Christopher Wolff, Christian Hausmann, Nan Zhang, Michaela Sochorová, Andrej Kováčik, et al. "Ultrastructural and Molecular Analysis of Ribose-Induced Glycated Reconstructed Human Skin." International Journal of Molecular Sciences 19, no. 11 (November 8, 2018): 3521. http://dx.doi.org/10.3390/ijms19113521.

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Aging depicts one of the major challenges in pharmacology owing to its complexity and heterogeneity. Thereby, advanced glycated end-products modify extracellular matrix proteins, but the consequences on the skin barrier function remain heavily understudied. Herein, we utilized transmission electron microscopy for the ultrastructural analysis of ribose-induced glycated reconstructed human skin (RHS). Molecular and functional insights substantiated the ultrastructural characterization and proved the relevance of glycated RHS beyond skin aging. In particular, electron microscopy mapped the accumulation and altered spatial orientation of fibrils and filaments in the dermal compartment of glycated RHS. Moreover, the epidermal basement membrane appeared thicker in glycated than in non-glycated RHS, but electron microscopy identified longitudinal clusters of the finest collagen fibrils instead of real thickening. The stratum granulosum contained more cell layers, the morphology of keratohyalin granules decidedly differed, and the stratum corneum lipid order increased in ribose-induced glycated RHS, while the skin barrier function was almost not affected. In conclusion, dermal advanced glycated end-products markedly changed the epidermal morphology, underlining the importance of matrix–cell interactions. The phenotype of ribose-induced glycated RHS emulated aged skin in the dermis, while the two to three times increased thickness of the stratum granulosum resembled poorer cornification.
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Aoki, Yoshikazu, Rika Ohishi, Ryoichi Takei, Osamu Matsuzaki, Mitsunobu Mohri, Ken-ichi Saitoh, Komakazu Gomi, et al. "Effects of Recombinant Human Soluble Thrombomodulin (rhs-TM) on a Rat Model of Disseminated Intravascular Coagulation with Decreased Levels of Plasma Antithrombin III." Thrombosis and Haemostasis 71, no. 04 (1994): 452–55. http://dx.doi.org/10.1055/s-0038-1642459.

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SummaryWe reported that recombinant human soluble thrombomodulin (rhs- TM) is effective for disseminated intravascular coagulation (DIC) in vivo, in mice and rats. In the present work, we investigated the effects of decreased plasma antithrombin III (ATIII) levels on anticoagulant effects of rhs-TM, as compared to findings with heparin, of which effect is lowered by the decreased plasma ATIII levels in patients with DIC. Rat plasma ATIII levels decreased when we mixed plasma with anti-rat ATIII antibody and the potential of heparin to prolong APTT or PT was markedly diminished. The potential of rhs-TM to prolong APTT and PT was not affected. In rats injected with anti-rat ATIII antibody, plasma ATIII levels decreased immediately. When the rats were infused with tissue factor (TF), DIC was induced. At doses of rhs-TM and heparin which were equally effective at inhibiting the decrease in platelet count and fibrinogen level in cuntiol rats treated with TF, only rhs-TM remained effective in preventing DIC in rats with reduced ATIII levels. Heparin was not effective, when administered to these rats with reduced ATIII levels. Therefore, rhs-TM effectively inhibits coagulation independent of ATIII levels, in contrast to heparin, which depends on the ATIII level.
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Post, Phillip C., and Mark A. Schlautman. "Measuring Camellia Petal Color Using a Portable Color Sensor." Horticulturae 6, no. 3 (September 3, 2020): 53. http://dx.doi.org/10.3390/horticulturae6030053.

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The color of petals of flowering plants is often determined by comparing one or more of the petals to various Royal Horticultural Society (RHS) Colour Chart cards until a color match is found. However, these cards are susceptible to fading with age and can also provide inaccurate results if lighting is not optimal. The cards also rely on the human eye to determine a match, which introduces the possibility of human error. The objectives of this study were to determine camellia (Camellia japonica L.) petal color using the RHS Colour Chart, to determine camellia petal color with the NixTM Pro color sensor (Nix Sensor Ltd., Hamilton, Ontario, Canada), and to compare these measurements using different color measuring approaches. Color measurements of camellia flower petals using the NixTM Pro color sensor were compared to published CIELAB values from the Royal Horticultural Society (RHS) Colour Chart. Forty-five petal color samples were collected from fifteen different camellia shrubs. The RHS Colour Chart was used for each of the petals, and the RHS identifications were recorded. Measurements using the NixTM Pro color sensor were compared to RHS-provided CIELAB values that corresponded with the recorded identification for each petal to determine accuracy. The NixTM Pro color sensor’s measurements were also compared to a mean of the values, multiple measurements on the same petal location, and multiple measurements on different petal locations to determine precision and variation. The Nix™ Pro color sensor’s readings were precise in petal color determination and provided more nuanced differences between petals of the same plant and plants of the same variety in each of the color categories. The RHS Colour Chart provided an accurate depiction of most petals, but it was difficult to use with petals that had wide color variation over the entire petal. The Nix™ Pro color sensor’s measurements appeared to have more variation in the b* color space. However, overall, the Nix™ Pro color sensor L*, a*, and b* values were highly correlated with the provided RHS values (p < 0.01), showing that the sensor can be used as an accurate and precise substitute for the RHS Colour Chart. The Nix™ Pro color sensor can be a useful, cost-effective tool to measure the petal color of camellia and other flowering plants and rectifies many of the problems associated with the RHS Colour Chart.
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Najjar, Mohammad S., and Laila Dahabiyeh. "Trust in the Ride Hailing Service of the Sharing Economy." Journal of Organizational and End User Computing 33, no. 6 (November 2021): 1–24. http://dx.doi.org/10.4018/joeuc.20211101.oa10.

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This paper examines the factors that influence customers’ trust in the ride hailing service (RHS). RHS faces legal, social, and safety concerns making trust critical in using RHS. Drawing on legitimacy and uncertainty reduction theories, we propose a theoretical framework of the antecedents of trust. We develop a survey instrument and collect data to empirically test the research model. The results reveal an association between the legitimacy of the service and customers’ trust in the service. Nonetheless, the different types of legitimacy vary in their effect on trust levels. We further show that process transparency positively affects trust in RHS. We discuss our findings and offer valuable theoretical and practical implications to the growing literature on trust in the sharing economy.
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ohishi, Rika, Naoko watanabe, Masaharu Aritomi, Komakazu Gomi, Takao Kiyota, Shuji Yamamoto, Torao lshida, and Ikuro Maruyama. "Evidence that the Protein C Activation Pathway Amplifies the lnhibition of Thrombin Generation by Recombinant Human Thrombomodulin in Plasma." Thrombosis and Haemostasis 70, no. 03 (1993): 423–26. http://dx.doi.org/10.1055/s-0038-1649598.

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SummaryThrombomodulin (TM) is a cofactor for the thrombin-catalyzed activation of anticoagulant protein C. However, we have no evidence that thrombomodulin actually activates protein C during blood coagulation processing, nor do we know whether this activated protein C acts as an anticoagulant. We studied the inhibitory action of recombinant human soluble TM (rhs-TM) on thrombin generation in whole plasma. Human plasma was activated with small amounts of tissue factor using phospholipid vesicles in place of activated platelets. Thrombin generation was observed. The addition of only 2 nM of rhs-TM prevented rapid generation of thrombin and reduced the total amount of thrombin generated. In order to study the influence of the protein C activation pathway on this inhibitory action of rhs-TM, protein C-depleted plasma was used. rhs-TM had little inhibitory effect on protein C-depleted plasma. However, the addition of protein C caused a delay in thrombin generation and a reduction of the maximum thrombin concentration. We concluded that the anticoagulant activity of rhs-TM was amplified by the protein C activation pathway.
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43

Choi, Gang Won, Junyang Jung, Seung Geun Yeo, and Sang Hoon Kim. "Presence of Varicella Zoster Virus DNA in Saliva May Be Associated with the Severity of Ramsay Hunt Syndrome." Biomedicines 10, no. 9 (September 2, 2022): 2177. http://dx.doi.org/10.3390/biomedicines10092177.

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Background: The relationship between varicella zoster virus (VZV) collected from saliva and Ramsay Hunt syndrome (RHS) remains unclear. Therefore, this study aimed to investigate whether VZV DNA in saliva alters the clinical symptoms and prognosis of RHS. Methods: To measure the severity of clinical symptoms of 100 RHS patients, the initial House–Brackmann (HB) grade and associated symptoms were evaluated. The final HB grade at the end of treatment was measured to determine the prognosis. Electroneurography (ENoG) was performed on four facial muscles, including the frontalis, oculi, nasalis, and oris. Results: Salivary VZV DNA was isolated from 72 patients with RHS. The VZV DNA-positive group was 34.023 times more likely to have severe initial HB grade than the control group (95% CI, 3.21–359.68; p = 0.003). There were no significant differences in final HB grade. All ENoG values of the VZV DNA-positive group were significantly higher than those of the control group (frontalis, p = 0.003; oculi, p = 0.001; nasalis, p < 0.001; oris, p = 0.037). Conclusions: RHS patients with salivary VZV DNA have more severe clinical symptoms than the control group. There were no differences in prognosis and associated symptoms. A VZV DNA test using saliva samples of patients with RHS can evaluate the clinical symptoms and provide early confirmation of VZV infection, enabling timely treatment in a non-invasive way.
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44

Donato, Sonya L., Christina M. Beck, Fernando Garza-Sánchez, Steven J. Jensen, Zachary C. Ruhe, David A. Cunningham, Ian Singleton, David A. Low, and Christopher S. Hayes. "The β-encapsulation cage of rearrangement hotspot (Rhs) effectors is required for type VI secretion." Proceedings of the National Academy of Sciences 117, no. 52 (December 15, 2020): 33540–48. http://dx.doi.org/10.1073/pnas.1919350117.

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Bacteria deploy rearrangement hotspot (Rhs) proteins as toxic effectors against both prokaryotic and eukaryotic target cells. Rhs proteins are characterized by YD-peptide repeats, which fold into a large β-cage structure that encapsulates the C-terminal toxin domain. Here, we show that Rhs effectors are essential for type VI secretion system (T6SS) activity in Enterobacter cloacae (ECL). ECL rhs− mutants do not kill Escherichia coli target bacteria and are defective for T6SS-dependent export of hemolysin-coregulated protein (Hcp). The RhsA and RhsB effectors of ECL both contain Pro−Ala−Ala−Arg (PAAR) repeat domains, which bind the β-spike of trimeric valine−glycine repeat protein G (VgrG) and are important for T6SS activity in other bacteria. Truncated RhsA that retains the PAAR domain is capable of forming higher-order, thermostable complexes with VgrG, yet these assemblies fail to restore secretion activity to ∆rhsA ∆rhsB mutants. Full T6SS-1 activity requires Rhs that contains N-terminal transmembrane helices, the PAAR domain, and an intact β-cage. Although ∆rhsA ∆rhsB mutants do not kill target bacteria, time-lapse microscopy reveals that they assemble and fire T6SS contractile sheaths at ∼6% of the frequency of rhs+ cells. Therefore, Rhs proteins are not strictly required for T6SS assembly, although they greatly increase secretion efficiency. We propose that PAAR and the β-cage provide distinct structures that promote secretion. PAAR is clearly sufficient to stabilize trimeric VgrG, but efficient assembly of T6SS-1 also depends on an intact β-cage. Together, these domains enforce a quality control checkpoint to ensure that VgrG is loaded with toxic cargo before assembling the secretion apparatus.
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45

AL-Adham, Eithar K., Amal I. Hassan, Ahmed Shebl, and M. M. Hazem. "Evaluation of the therapeutic effects of rice husk nanosilica combined with platelet-derived growth factor in hepatic veno-occlusive disease." Biochemistry and Cell Biology 96, no. 5 (October 2018): 682–94. http://dx.doi.org/10.1139/bcb-2017-0248.

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Veno-occlusive disease is an important pattern of hepatotoxicity associated with antineoplastic drugs. The study investigated the possible therapeutic effects of RHS nanoparticles combined with a PDGF on veno-occlusive disease (VOD) in liver elicited in rats with DAC. In this work, nanosilica (SiO2) was successfully prepared from rice husk, and its physicochemical characteristics were investigated using EDX, XRD, N2adsorption–desorption isotherm, SEM, and TEM. Forty-eight male Sprague–Dawely rats were distributed into 6 groups, with 8 rats in each. The first group served as the control. In the second group, animals were infused with DAC (0.015 mg/kg; 1–3 days) by intraperitoneal injection (i.p.). In the third group, rats were injected i.p. with DAC, and then at 24 h following the last dose of DAC, received nano-RHS incorporated with PDGF twice a week for 4 weeks. In the fourth group, normal animals were injected with RHS. In the fifth group, normal rats received PDGF, and in the sixth group, normal rats received nano-RHS combined with PDGF. The prepared nanosilica showed type II adsorption isotherm characteristic for mesoporous materials with a specific surface area of 236 m2/g. TEM imaging confirmed the production of nanoparticles via the followed preparation procedure. Radical scavenging potential for nano-RHS was determined using two different in-vitro assays: DPPH, and ABTS radicals. The results of this work show that administration of nano-RHS combined with PDGF significantly reversed the oxidative stress effects of DAC as evidenced by a decrease in liver function. It can be concluded that the nano-RHS combined with PDGF is useful in preventing oxidative stress and hepatic VOD induced by chemotherapy such as DAC.
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46

Beletew Abate, Biruk, Kalkidan Habtamu Gelaw, Hayelom Fentaw, Mekonen Ashagire, and Tadesse Mekash. "Knowledge Level and Associated Factors of Reproductive Health Issues among Secondary School Students in Woldia Town, Amhara, Ethiopia, 2019: A Cross-Sectional Study." Journal of Environmental and Public Health 2020 (October 22, 2020): 1–9. http://dx.doi.org/10.1155/2020/2515292.

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Background. Reproductive health (RH) is defined as a state of complete physical, mental, and social wellbeing and not merely the absence of disease or infirmity, in all matters related to the reproductive system and to its functions and process. Local evidence about adolescents’ reproductive health knowledge level and associated factors are relevant to design age-appropriate interventions strategies. Therefore, the aim of this study was to assess the knowledge level on reproductive health issues among secondary school students in Woldia town. Objective. The main aim of this study was to assess the knowledge level and associated factors among adolescents in Woldia secondary schools, Amhara, Ethiopia, 2019. Methods. Institution-based descriptive cross-sectional study was conducted on 420 secondary school students in Woldia town from January to June 2019. Multistage sampling technique was employed. A self-administered, structured, and adapted questionnaire was used to collect the data. The data was entered by using EpiData version 4.2 and exported to SPSS version 24.0 for analysis. The samples were distributed proportionally based on probability proportional to size (PPS) allocation technique. Participants in each school have been selected by using systematic sampling technique after calculating sample interval (K) for each school. Bivariate and multivariable logistic regressions were carried out to assess the association between dependent and independent variables. Result. The prevalence of good knowledge was 204 (48.6%). Residence, educational level, handling of RHS providers, ever gone RHS institution and missed RHS service, had RHS in school, and stigma to utilize RHS were found to be significantly associated with the level of knowledge of respondents on reproductive health issues. Conclusion and Recommendations. The knowledge of respondents on reproductive health issues in the study area was found to be low. Hence, it is better to improve access to information to the secondary school students on RHS through trained health workers and accessible RHS.
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47

Jian, JianHua, Dilip K. Lakshman, and Stellos M. Tavantzis. "Association of Distinct Double-Stranded RNAs with Enhanced or Diminished Virulence in Rhizoctonia solani Infecting Potato." Molecular Plant-Microbe Interactions® 10, no. 8 (November 1997): 1002–9. http://dx.doi.org/10.1094/mpmi.1997.10.8.1002.

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A virulent field isolate of Rhizoctonia solani AG 3, Rhs 1AP, has given rise to three sectors in a period of several years. Subculturing of these sectors resulted in three hypovirulent isolates—Rhs 1A1, Rhs 1A2, and Rhs 1A3. We reported previously that five genetically different double-stranded (ds) RNAs occur in these four isolates, with each isolate containing a unique combination of two or more dsRNAs. We report here that all five dsRNA elements occur in the cytoplasm, and none in the nucleus. The mitochondria contains low to moderate concentrations of the four larger dsRNAs. The four isolates were paired in selected combinations in an attempt to transmit specific dsRNAs to cultures lacking these dsRNAs. This approach generated groups of near-isogenic lines possessing the same dsRNA elements. As many as six cultures possessing the same dsRNA genotype were found to have the same degree of pathogenicity. Consistently, acquisition of a 6.4-kb dsRNA brought about increased virulence, whereas the presence or acquisition of a 3.6-kb dsRNA resulted in diminished virulence in the recipient culture. All cultures had the same mitochondrial DNA haplotype as that of the original field isolate, Rhs 1AP. This, in conjunction with the fact that all cultures in this study had a single nuclear DNA origin (Rhs 1AP), indicates a strong correlation between certain phenotypic characters or changes thereof and dsRNA profiles or acquisition of particular dsRNAs, respectively.
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48

Yoon, Tae-Hyun, Tae-Sung Eom, Chul-Goo Kim, and Su-Min Kang. "Behavior of Longitudinal Plate-to-Rectangular Hollow Structural Section K-Connections Subjected to Cyclic Loading." Applied Sciences 10, no. 11 (May 29, 2020): 3793. http://dx.doi.org/10.3390/app10113793.

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This study investigated the behavior of longitudinal plate-to-rectangular hollow section (RHS) K-connections to which concrete-filled composite branch members were jointed. At the connections, longitudinal plates with or without chord face stiffener were welded to the RHS chord member and the branch members were connected to the longitudinal plates by bolting (slip-critical connection). Cyclic tests were performed for three longitudinal plate-to-RHS K-connection specimens. The tests showed that the connection behavior was dominated by the plastification of the thin chord face and by the slip and hole-bearing resistance of the bolted joint. Chord face plastification was prevented or delayed by using the stiffened longitudinal plate. The strengths of the plate-to-RHS K-connections with or without the chord face stiffener, depending on the governing limit states, were estimated in accordance with current design codes, and the results were compared with the test results.
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49

J.E., Ibebuike,, Onyeneke, U.J., and Chinedu-Eleonu, P. "Reproductive Health Services in Owerri West Local Government Area, Imo State, Nigeria: Youths and Providers’ Perspective." International Journal of Science and Healthcare Research 6, no. 3 (August 11, 2021): 208–15. http://dx.doi.org/10.52403/ijshr.20210736.

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Reproductive health is central to human identity and imperative for health and well-being. This study was carried out in Owerri West Local Government Area of Imo State, Nigeria to investigate the perspective of youths and providers of reproductive health services toward its utilization and challenges. The study was a descriptive cross sectional study of which the multistage sampling technique was adopted to select samples for the study. A well-structured questionnaire was used to interview the subjects all of gave an informed consent to be part of the study. Results showed that the youth’s view on impending factors of RHS include attitude of RHS workers, cost of provision of RHS, poor keeping of secret about one’s health, lack of confidentiality among workers, parental influence, poor environment and poor road accessibility and lack of confidentiality. The providers generally identified the role RHS play in terms of family planning, antenatal care services, treatment of unsafe abortion, referral services, treatment and prevention of sexually transmitted infections, etc. They were of the view that some of the impediments affecting quality RHS in their communities were poor environment, lack of privacy, poor maintenance of the buildings for health care, fear of the elderly, poor attitude of some of the health workers, lack of accessible roads leading to health centers, poor availability of equipment and product supplies, treatment cost, etc. It was recommended that health awareness campaigns concerning RHS and its associating risk factors should be made more pronounced in the society especially among youths. Keywords: Reproductive Health Services, Sexual and Reproductive Health, Youths, Providers, Sexually Transmitted Infections.
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50

Guerrero Núñez, Juan. "Densidad de recurso humano y desigualdad en gastos en salud en países de las Américas." Revista Panamericana de Salud Pública 44 (November 11, 2020): 1. http://dx.doi.org/10.26633/rpsp.2020.133.

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Objetivo. Determinar existencia de desigualdad y gradiente en gastos de bolsillo, gasto público y gasto privado, entre países americanos estratificados según su densidad de recurso humano en salud (RHS). Métodos. Estudio analítico y transversal de desigualdades en salud para el gasto de bolsillo (porcentaje del gasto total en salud), el gasto público y el gasto privado (porcentaje del PIB), aplicando la densidad de recurso humano (medicina más enfermería) como estratificador. A partir de datos de la Organización Panamericana de la Salud y el Banco Mundial se categorizaron 32 países americanos según su densidad, se calcularon tasas ponderadas, descriptivos, diferencias, correlaciones, indicadores simples y complejos de desigualdad. Resultados. Hay alta variabilidad de densidad de RHS (3,8 a 171,3; media de 43,97, DS 37,08) con diferencias significativas entre las categorías de alta y baja densidad. El primer cuartil concentra el 9% de la población y 4,45% del RHS; los 3 primeros cuartiles concentran el 48,4% de la población y el 17% del RHS. Mediante estratificación, se evidenció un gradiente y desigualdades en indicadores de gastos, mayor en el gasto de bolsillo, con el cual también la densidad de RHS presentó una correlación negativa. Conclusiones. La densidad de RHS presenta alta variabilidad entre países y grupos categorizados; se concentra en forma desigual en la población, y es mayor en los países con mayor gasto público. Como estratificador de la muestra permitió evidenciar desigualdades y gradientes de gastos en salud; los estratos de menor densidad presentan mayor gasto de bolsillo, menor gasto público y mayor gasto privado.
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