Dissertations / Theses on the topic 'Rhinosinusitis'
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Sharman, Mellora J. "Mycotic rhinosinusitis in dogs." Thesis, Sharman, Mellora J (2011) Mycotic rhinosinusitis in dogs. Masters by Research thesis, Murdoch University, 2011. https://researchrepository.murdoch.edu.au/id/eprint/5816/.
Full textVaidyanathan, Sriram. "Optimising therapeutic strategies for chronic rhinosinusitis." Thesis, University of Dundee, 2014. https://discovery.dundee.ac.uk/en/studentTheses/337b63fd-4590-4ef9-a55f-8bf447986906.
Full textErskine, Sally. "The epidemiology and experience of chronic rhinosinusitis." Thesis, University of East Anglia, 2017. https://ueaeprints.uea.ac.uk/66950/.
Full textKysylytsia, S. O. "Conservative methods of treatment of acute rhinosinusitis." Thesis, БДМУ, 2022. http://dspace.bsmu.edu.ua:8080/xmlui/handle/123456789/19365.
Full textХижня, Ярослава Володимирівна, Ярослава Владимировна Хижня, Yaroslava Volodymyrivna Khyzhnia, В. С. Бабич, and В. І. Ситнік. "Антибіотикотерапія гострого риносинусита." Thesis, Видавництво СумДУ, 2003. http://essuir.sumdu.edu.ua/handle/123456789/9373.
Full textKristo, A. (Aila). "Acute rhinosinusitis during upper respiratory infection in children." Doctoral thesis, University of Oulu, 2005. http://urn.fi/urn:isbn:9514278720.
Full textVento, Seija. "Nasal polypoid rhinosinusitis : clinical course and etiological investigations." Helsinki : University of Helsinki, 2001. http://ethesis.helsinki.fi/julkaisut/laa/kliin/vk/vento/.
Full textHisir, Selma [Verfasser]. "Nosologie, Komorbiditäten und Kausalitäten der chronischen Rhinosinusitis / Selma Hisir." Ulm : Universität Ulm, 2018. http://d-nb.info/1161008586/34.
Full textAutio, T. (Timo). "Development and diagnostics of bacterial acute rhinosinusitis in young adults." Doctoral thesis, Oulun yliopisto, 2017. http://urn.fi/urn:isbn:9789526214726.
Full textTiivistelmä Nenän äkillinen sivuontelotulehdus on tavallinen tauti, jonka hoitoon käytetään paljon antibiootteja, vaikka sen aiheuttaja on useimmiten virus. Bakteerin aiheuttaman tautimuodon kehittymisestä ja diagnostiikasta ei ole julkaistu tutkimuksia, joissa potilaita olisi seurattu taudin alusta lähtien ja bakteerin olemassaolo olisi varmistettu nenän sivuontelosta otetulla bakteerinäytteellä. Tämän väitöskirjatyön tarkoituksena oli selvittää nenän äkillisen sivuontelotulehduksen kulkua käyttämällä toistuvia, standardisoituja menetelmiä. Bakteerin aiheuttama tauti todettiin poskiontelopistolla ja bakteeriviljelyllä. Tutkimukseen osallistui viisikymmentä (50) äkilliseen ylähengitystieinfektioon sairastunutta varusmiestä keväällä 2012. Kahdeksalla (16 %) potilaalla todettiin bakteerin aiheuttama tauti poskiontelopiston avulla 9–10 päivää oireiden alkamisen jälkeen. Viruksen ja bakteerin sekainfektio aiheutti laajemmat sivuonteloiden tulehduslöydökset ja voimakkaammat oireet kuin pelkän viruksen aiheuttama tauti. Sivuonteloiden tulehduslöydökset kehittyivät nopeasti ja pysyivät sekä bakteerin että viruksen aiheuttamassa taudissa varsin muuttumattomina. Tulehdusmerkkiaineiden muutokset osoittivat sekä paikallisen, että yleisen tulehdusreaktion, jotka olivat voimakkaimmillaan taudin alussa. Oireet tai niissä taudin aikana tapahtuneet muutokset eivät osoittautuneet hyviksi merkeiksi bakteerin aiheuttaman taudin toteamiseksi, mutta eritteen näkyminen nenässä, nielussa tai keskikäytävässä ennakoi hyvin bakteerin aiheuttaman sivuontelotulehduksen toteamista. Bakteeri saattaa vaikuttaa oireisiin ja sivuonteloiden tulehduslöydöksiin jo nenän äkillisen sivuontelotulehduksen alussa, mutta tulehduslöydösten laajuus ei välttämättä liity bakteerin aiheuttaman taudin kehittymiseen. Nenän äkilliseen sivuontelotulehdukseen liittyy paikallinen ja yleinen tulehdusreaktio, jotka ovat voimakkaimmillaan taudin alussa. Potilaan nenän ja nielun tutkiminen on tärkeää bakteerin aiheuttaman nenän sivuontelotulehduksen toteamiseksi
Wallwork, Benjamin, and n/a. "The Anti-Inflammatory Effect of Macrolide Antibiotics in Chronic Rhinosinusitis." Griffith University. School of Biomolecular and Biomedical Science, 2006. http://www4.gu.edu.au:8080/adt-root/public/adt-QGU20070201.160023.
Full textWallwork, Benjamin. "The Anti-Inflammatory Effect of Macrolide Antibiotics in Chronic Rhinosinusitis." Thesis, Griffith University, 2006. http://hdl.handle.net/10072/367299.
Full textThesis (PhD Doctorate)
Doctor of Philosophy (PhD)
School of Biomolecular and Biomedical Sciences
Full Text
Migliavacca, Raphaella de Oliveira. "Modelo experimental de rinossinusite crônica em coelhos sem utilização de bactérias : comparação de técnicas de indução." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2012. http://hdl.handle.net/10183/61886.
Full textExperimental models have an important role in understanding the mechanisms involved in the pathogenesis of chronic rhinosinusitis (CRS). Objectives: To demonstrate that, without the inoculation of pathogenic bacteria, it is possible to induce chronic histological changes in the maxillary sinuses of rabbits secondary to sinus ostium obstruction, producing a consistent and reproducible experimental model for CRS. Secondly, to compare inflammatory findings between two techniques of experimental occlusion of the maxillary sinus ostium with N-butyl cyanoacrylate: transmaxillary and through the roof of the nasal cavity. Methods: In a randomized, blinded, experimental study, 16 New Zealand rabbits were assigned for occlusion of the right maxillary sinus through a transmaxillary approach or through the roof of the nasal cavity. The contralateral sinus was left undisturbed to serve as a control. After 12 weeks of follow-up, the animals were anesthetized and sacrificed for blinded histopathological analysis of the maxillary sinus mucosa. Results: Histopathological changes consistent with CRS were found in eight (100%) of the maxillary sinuses approached transmaxillary and three of thoseapproached through the roof of the nasal cavity (37.5%), p 0.008 and 0.250, respectively, comparing the right to the left control sinus. Comparing the occlusion techniques, the transmaxillary approach was more consistent in causing chronic mucosal changes (p 0.026). Conclusions: The proposed model was successful in causing histological changes compatible with CRS in animals subjected to sinus occlusion with a transmaxillary approach followed-up for 12 weeks. This experimental model can be easily replicated for future cellular studies of the sinus mucosa.
Merse, Stefanie [Verfasser], and Philipp [Akademischer Betreuer] Dost. "Intranasale Reflex-Therapie bei chronischer Rhinosinusitis / Stefanie Merse. Betreuer: Philipp Dost." Duisburg, 2015. http://d-nb.info/1077439210/34.
Full textJategaonkar, Ameya. "Management of Rhinosinusitis During Pregnancy: Systematic Review and Expert Panel Recommendations." Thesis, The University of Arizona, 2016. http://hdl.handle.net/10150/603631.
Full textBackground: Rhinosinusitis, both acute and chronic, represents a common disease. Approximately 29.6 million adults in the United States suffer from sinusitis with 11 million suffering from CRS1. The multicenter GA2LEN study showed that amongst lifetime nonsmokers, women were at a greater risk of being affected by chronic rhinosinusitis than men2. Various other rhinologic manifestations of pregnancy have also been described. Nevertheless, management of rhinosinusitis during pregnancy is poorly described in the literature. Objectives: 1. Conduct a systematic review of the literature for the management of acute and chronic rhinosinusitis (CRS) during pregnancy. 2. Make evidence based recommendations on the management of acute and chronic rhinosinusitis during pregnancy. Methods: A systematic review of the literature was conducted using MEDLINE and EMBASE databases. Search terms included “rhinitis” OR “sinusitis” OR “rhinosinusitis” AND “pregnant” OR “women” OR “gender”. Title, abstract, and full manuscript review was conducted. Full manuscripts including citations and references were reviewed if the abstract noted any gender specific outcomes. A multispecialty panel of experts in the fields of rhinology, allergyimmunology, and obstetrics‐gynecology was invited to review the systematic review. Recommendations were sought on the use of the following for the management of CRS during pregnancy: oral corticosteroids, antibiotics, leukotriene antagonists, topical corticosteroid sprays/irrigations/drops, aspirin desensitization, elective surgery for CRS, and vaginal birth vs. planned cesarean delivery for patients with history of skull base erosions or CSF rhinorrhea. Results: 3052 abstracts were screened, and 88 manuscripts were reviewed. No relevant level 1, 2 or 3 studies were found. Expert panel recommendations were synthesized. Conclusions: Several recommendations were made. These include continuing all modern topical corticosteroids for CRS maintenance, using pregnancy safe antibiotics for acute rhinosinusitis and CRS exacerbations, and discontinuing aspiring therapy for desensitization in patients with aspirin exacerbated respiratory disease.
Cardoso, Isabel Cristina Espíndola. "Aspectos clínicos, epidemiológicos e etiológicos de 82 casos de rinossinusite fúngica no Rio Grande do Sul." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2016. http://hdl.handle.net/10183/150992.
Full textDescription: The fungal rhinosinusitis (FRS) is an opportunistic infection characterized by inflammation of the nasal mucosa and sinuses. It is considered an emerging problem in daily medical practice, with prevalence increased in recent decades, with etiology in diverse ubiquitous fungi. Objectives: This study aimed to analyze all cases of RSF belonging to the Mycology Laboratory of the database of the Brotherhood of the Santa Casa of Misericordia Porto Alegre during the period of 28 years (1986-2014), relating them with the clinical and epidemiological characteristics. Methods: The study was observational retrospective, resulting in a series of 82 cases confirmed by histopathological and mycological examinations for identification of fungi, compared them with the findings on radiographs. Results: We identified 54 cases of aspergillosis by RSF, especially the etiologic agent Aspergillus fumigatus (14/54), and 27 cases of RSF different fungi Aspergillus, with insulation superiority of agents responsible for hyalohyphomycosis (12/27). Configured, these findings, the three cases unprecedented in our country, especially the first case of human infection with RSF and Trichoderma asperellum. Conclusions: These findings represent the largest identified Brazilian series and can contribute to a better epidemiological understanding, improving clinical suspicion criteria, reflecting the effectiveness of treatments, mainly in diagnosing cases of invasive RSF, with high mortality rates.
Марцинковська, І. Р., and Ю. В. Донецька. "Лікування поліпозного риносинуситу: рецидиви та вплив на бронхіальну астму." Thesis, Сумський державний університет, 2017. http://essuir.sumdu.edu.ua/handle/123456789/58123.
Full textХижня, Ярослава Володимирівна, Ярослава Владимировна Хижня, Yaroslava Volodymyrivna Khyzhnia, Т. О. Грицай, В. А. Сухарєва, and А. В. Грищенко. "Досвід застосування препарату "Фламідез" у хворих на гострий риносинусит." Thesis, Сумський державний університет, 2017. http://essuir.sumdu.edu.ua/handle/123456789/58161.
Full textWhitney, Joanna. "Immunopathogenesis of feline upper respiratory tract aspergillosis." Thesis, The University of Sydney, 2019. https://hdl.handle.net/2123/21338.
Full textViswanathan, Harishnath. "Mucin Gene Expression and GastricReflux in Chronic Rhinosinusitis and Otitis Media with Effusion." Thesis, University of Newcastle Upon Tyne, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.499336.
Full textFuchs, Christine [Verfasser]. "Charakterisierung des Th2-Shifts bei Patienten mit chronischer Rhinosinusitis mit Polypen / Christine Fuchs." Ulm : Universität Ulm. Medizinische Fakultät, 2013. http://d-nb.info/1038004837/34.
Full textBall, Stephen Leslie. "The role of epithelial cells and fibroblasts in the pathogenesis of chronic rhinosinusitis." Thesis, University of Newcastle upon Tyne, 2017. http://hdl.handle.net/10443/3726.
Full textBlaeser, Christiane [Verfasser]. "Die Behandlung der Rhinosinusitis durch Dexamethason : eine doppelblinde, randomisierte, Placebo-kontrollierte Studie / Christiane Blaeser." Köln : Deutsche Zentralbibliothek für Medizin, 2013. http://d-nb.info/1034434527/34.
Full textKuchai, Romana. "The effect of macrolides on allergic rhinitis versus chronic rhinosinusitis- an in-vitro study." Thesis, Queen Mary, University of London, 2009. http://qmro.qmul.ac.uk/xmlui/handle/123456789/568.
Full textPilavakis, Yiannis [Verfasser]. "Occurence and characteristics of allergic rhinitis in 195 patients with chronic rhinosinusitis / Yiannis Pilavakis." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2020. http://d-nb.info/1223171612/34.
Full textEitenmüller, Anna-Katharina [Verfasser]. "Liposomen als Alternative zu Steroiden bei der Behandlung der chronischen Rhinosinusitis / Anna-Katharina Eitenmüller." Köln : Deutsche Zentralbibliothek für Medizin, 2014. http://d-nb.info/106627696X/34.
Full textХижня, Ярослава Володимирівна, Ярослава Владимировна Хижня, and Yaroslava Volodymyrivna Khyzhnia. "Досвід застосуваня препарату "Серрата" у хворих на гострий риносинусит." Thesis, Видавництво СумДУ, 2012. http://essuir.sumdu.edu.ua/handle/123456789/27032.
Full textHabib, Al-Rahim. "Association between chronic rhinosinusitis and health-related quality of life in adults with cystic fibrosis." Thesis, University of British Columbia, 2014. http://hdl.handle.net/2429/50407.
Full textMedicine, Faculty of
Population and Public Health (SPPH), School of
Graduate
Koch, Barbara [Verfasser], and Ulrich [Akademischer Betreuer] Köhler. "Nächtliche akustische Langzeitregistrierung von Atemgeräuschen bei Patienten mit chronischer Rhinosinusitis / Barbara Koch. Betreuer: Ulrich Köhler." Marburg : Philipps-Universität Marburg, 2012. http://d-nb.info/1027184170/34.
Full textHeller, Lisa-Marie [Verfasser], and Rainald [Akademischer Betreuer] Knecht. "Digitale Volumentomographie als präoperative diagnostische Modalität bei chronischer Rhinosinusitis / Lisa-Marie Heller. Betreuer: Rainald Knecht." Hamburg : Staats- und Universitätsbibliothek Hamburg, 2016. http://d-nb.info/1093411465/34.
Full textHeller, Lisa-Marie Verfasser], and Rainald [Akademischer Betreuer] [Knecht. "Digitale Volumentomographie als präoperative diagnostische Modalität bei chronischer Rhinosinusitis / Lisa-Marie Heller. Betreuer: Rainald Knecht." Hamburg : Staats- und Universitätsbibliothek Hamburg, 2016. http://d-nb.info/1093411465/34.
Full textCordeiro, Daniel Loiola. "Doença respiratória exacerbada por aspirina: papel da periostina em pacientes com rinossinusite crônica e polipose nasossinusal." Universidade de São Paulo, 2018. http://www.teses.usp.br/teses/disponiveis/17/17138/tde-18072018-154146/.
Full textAspirin exacerbated respiratory disease (also known as AERD), is characterized by eosinophilic chronic hypertrophic rhinosinusitis, nasosinusal polyps, asthma and hypersensitivity to Aspirin or other non-steroidal anti-inflammatory drugs. A higher expression of the biomarker periostin has been described in patients with AERD, in nasosinusal tissue, including basal membrane, extracellular matrix and nasal polyps. We evaluated the levels of serum periostin in patients with AERD, and compare those levels with patients with perennial allergic rhinitis (PAR), and with healthy subjects. Twenty-nine patients (20F/9M) with AERD were selected from the Allergy and Otolaryngology Clinics, from the Clinical Hospital of the Ribeirão Preto Medicine School, University of São Paulo (HCFMRP-USP). Those patients underwent confirmatory exams, such as Oral Provocation test with aspirin, and were submitted to polyp biopsy through nasofibroscopy. As a control group, 12 patients (9F/3M) with PAR and 23 healthy subjects (14F/9M) were selected. Eosinophils were quantified in peripheral blood and in polyp tissue or nasal mucosa. Total IgE was determined by ImmunoCAP, and serum periostin was measured by ELISA. The number of tissue eosinophils by high magnification field (HMF), number of eosinophils by cubic milliliter in peripheral blood, total IgE levels and serum periostin levels in patients with AERD were compared with those from patients with PAR and healthy subjects. Patients with AERD were older (median 54 years, and range 22-60) than patients with PAR (median 30 years, range 19-57, p=0,0001) and healthy subjects (median 29 years, range 19-53, p=0,0001), with no difference between genders. The numbers of eosinophils in peripheral blood and in tissue were higher in patients with AERD than patients with PAR or healthy subjects. The median of eosinophil number in peripheral blood was 640eos/µL (range 100-5.100); 200eos/µL (range 100-500); e 100eos/µL (range 100-400) in patients with AERD, PAR and healthy subjects respectively (AERD vs PAR, p=0,0003; AERD vs healthy subjects, p=0,01). The average number of tissue eosinophils was 113,3cels/HMF; 2,5cels/HMF; e 0,7cels/HMF, respectively (AERD vs PAR, p=0,017; AERD vs healthy subjects, p=0,003). The geometric mean for total IgE was 290,18kU/mL (range 59,5-8.140); 69,96kU/mL (range 5,5-898); and 43,14kU/mL (range 4-1.328) in patients with AERD, PAR and healthy subjects respectively, with no difference between the groups. Serum periostin was higher in patients with AERD when compared with healthy subjects. The median for serum periostin was 602ng/ml (range 290,7-1.055); 535,6ng/mL (range 209-733,2); e 496,7ng/mL (range 327,4-713,4), in patients with AERD, PAR and healthy subjects respectively (AERD vs healthy subjects, p=0,01). In a Brazilian subgroup of patients with AERD, we observed an elevated number of eosinophils in peripheral blood and tissue, when compared with patients with PAR and healthy subjects. Higher levels of serum periostin were observed in patients with AERD, when compared with healthy subjects, indicating a strong type 2 response in patients with AERD in our environment.
Thompson, Melissa. "Anti-Inflammatory Properties of Xylitol in a Model of Chronic Sinus Disease." Thesis, Griffith University, 2013. http://hdl.handle.net/10072/367231.
Full textThesis (Masters)
Master of Philosophy (MPhil)
School of Pharmacy
Griffith Health
Full Text
Tewfik, Marc. "A population-based association study of toll-like receptor signaling pathway gene polymorphisms in chronic rhinosinusitis." Thesis, McGill University, 2009. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=66766.
Full textLa rhinosinusite chronique (RSC) est une maladie fréquente qui cause l'inflammation des sinus. Les récepteurs Toll-like (TLR) sont importants dans l'immunité innée, répondant aux microorganismes. Nous avons évalué les polymorphismes ponctuels de séquence (SNPs) dans les gènes codant les voies de signalisation TLR chez 206 patients atteints de RSC sévère et 200 témoins. Nous avons aussi investigué l'association entre ces SNPs et le niveau d'IgE sanguin. En tout, 96 sur 104 SNPs ont été génotypés avec succès. Bien que nous ne pouvions pas confirmer l'association avec la RSC, 3 SNPs dans le gène IRAK4 – rs1461567, rs4251513, and rs4251559 – étaient associés a un niveau d'IgE sanguin élevé (p < 0.004). Le résultat a été répliqué dans une seconde population indépendante d'individus souffrant d'asthme provenant du Saguenay-Lac-Saint-Jean (p < 0.031). Ces résultats suggèrent qu'une modification génétique dans le gène IRAK4 prédispose à un niveau élevé d'IgE dans les maladies respiratoires.
Cope, Emily K., Andrew N. Goldberg, Steven D. Pletcher, and Susan V. Lynch. "Compositionally and functionally distinct sinus microbiota in chronic rhinosinusitis patients have immunological and clinically divergent consequences." BIOMED CENTRAL LTD, 2017. http://hdl.handle.net/10150/624075.
Full textGutsche, Manuela. "Polyposis nasi: Quantitative Analyse der eosinophilen Granulozyten mit der Laser Scanning Zytometrie." Doctoral thesis, Universitätsbibliothek Leipzig, 2011. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-64179.
Full textЛозовий, Р. О. "Хронічний поліпозний риносинусит. Сучасні аспекти лікування." Thesis, Сумський державний університет, 2016. http://essuir.sumdu.edu.ua/handle/123456789/45160.
Full textRagab, Sameh Mostafa. "Evaluation of the medical and surgical treatment of chronic rhinosinusitis and its effects upon the lower airways." Thesis, University College London (University of London), 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.271395.
Full textSprügel, Lisa Melanie [Verfasser], and Stephan [Gutachter] Hackenberg. "Pilzantigene als spezifische T-Zellaktivatoren bei der chronischen Rhinosinusitis / Lisa Melanie Sprügel [verh. Kappenberger] ; Gutachter: Stephan Hackenberg." Würzburg : Universität Würzburg, 2021. http://d-nb.info/1233602993/34.
Full textTraser, Louisa [Verfasser]. "Differenzierung der chronischen Rhinosinusitis mit und ohne Polyposis nasi anhand von Symptomatik, Krankheitsverlauf, Entzündungsmediatoren und Komorbiditäten / Louisa Traser." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2011. http://d-nb.info/1029846677/34.
Full textDinarte, Vanessa Ramos Pires. "Associação genética do polimorfismo do receptor alfa 1 da interleucina 22 à rinossinusite crônica com e sem polipose nasossinusal." Universidade de São Paulo, 2017. http://www.teses.usp.br/teses/disponiveis/17/17151/tde-26042018-171434/.
Full textIntroduction: Chronic rhinosinusitis (CRS), a multifactorial disease, with genetic and environmental factors that may be involved, still have many aspects of its pathogenesis unknown. Genetics has shown itself promising in the elucidation of this complex disease. Some studies have indicated that the expression of IL-22 is reduced in patients with CRS, which may result in reduction of the epithelial barrier and decrease in the production of Th1 proinflammatory cytokines. Objectives: To investigate the frequency of polymorphisms in the IL22RA1 gene in patients with chronic rhinosinusitis with and without nasal polyps and in individuals without these pathologies, using the Sanger sequencing technique for mutation analysis; to compare the frequencies of the polymorphisms found in the IL22RA1 gene between the groups and the medical literature and also to compare the Sanger technique with other conventional techniques in the medical literature. Casuistic and Methods: From May 2011 to February 2016, 247 patients were evaluated, subdivided into three groups: 122 patients with chronic rhinosinusitis with nasal polyps (CRSwNP), 21 cases of chronic rhinosinusitis without nasal polyps (CRSsNP) and 104 volunteers without nasal symptoms. Samples of peripheral venous blood were collected from all cases and controls, and DNA extraction was performed, with subsequent analysis at the Molecular Genetics Laboratory - Ribeirão Preto Medical School Blood Center - USP. After the loss exclusion, there were 70 cases of CRSwNP, 14 CRSsNP and 68 controls. Results: Sequencing indicated 10 polymorphisms in the IL22RA1 gene, exon 2 (rs10903022, c.113_114insA / Q26Pfs * 11, c.74T> A and c.141C> A), exon 4 (rs17852649), exon 5 (rs16829204), exon 6 (rs142356961) and exon 7 (rs17852648, rs34967816 and rs3795299). Polymorphisms in exons 2 (in homozygosis), 5 and 6 were exclusive from the analyzed pathologies group (RSC with and without NP), the latter two being considered non-synonymous variables, that is, with capacity to alter the protein structure, being able to produce impact on the pathogenesis of CRS. The exon 6 alteration was the only variant found, with the minor allele frequency (MAF) under 0.01, exclusive of the RSCcPN group. Conclusions: Three polymorphisms were detected in the IL22RA1 gene, which until now are not described in the literature, and the possibly pathogenic insert c.113_114insA / Q26Pfs * 11, with a higher frequency in the groups with CRS. The polymorphism rs17852649 in heterozygosis in exon 4 was the only one with a statistical difference, with predominance of the mutated allele in the control group, which could confer protection against the phenotype. Also notable is the polymorphism rs142356961, in exon 6, of the non-synonymous type, that is, capable of altering the final structure of the protein, with MAF index <0.01, being exclusive in black patients with chronic rhinosinusitis with nasal polyps. Replication studies and larger cohorts are necessary to rule out the findings at random.
Macdonald, Kristian I. "Development and Validation of an Administrative Data Algorithm to Identify Adults who have Endoscopic Sinus Surgery for Chronic Rhinosinusitis." Thesis, Université d'Ottawa / University of Ottawa, 2016. http://hdl.handle.net/10393/35148.
Full textKönig, Katrin Elisabeth [Verfasser], and Moritz [Akademischer Betreuer] Gröger. "Cytokine profiles in nasal secretions of patients with allergic rhinitis and chronic rhinosinusitis / Katrin Elisabeth König ; Betreuer: Moritz Gröger." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2017. http://d-nb.info/1151447277/34.
Full textBebber, Martin van [Verfasser]. "Stellenwert der Bestimmung von Myeloperoxidase und PMN-Elastase im Nasensekret als Outcome-Parameter bei der akuten Rhinosinusitis / Martin van Bebber." Aachen : Shaker, 2006. http://d-nb.info/1186585439/34.
Full textBenecke, Frederick [Verfasser], Barbara [Akademischer Betreuer] Wollenberg, and Norbert [Akademischer Betreuer] Brüggemann. "Stickstoffmonoxid-Metabolismus in chronischer Rhinosinusitis mit Polypen unter Einflussnahme von 1,8-Cineol / Frederick Benecke ; Akademische Betreuer: Barbara Wollenberg, Norbert Brüggemann." Lübeck : Zentrale Hochschulbibliothek Lübeck, 2020. http://d-nb.info/1222766817/34.
Full textЛозовий, Р. О. "Хронічний поліпозний риносинусит. Сучасні аспекти лікування." Thesis, Сумський державний університет, 2016. http://essuir.sumdu.edu.ua/handle/123456789/48312.
Full textKoch, Michael [Verfasser], Karl [Akademischer Betreuer] Meßlinger, and Christian [Gutachter] Alzheimer. "Antworteigenschaften spinaler Trigeminusneurone auf noxische Stimulation der Nasennebenhöhlen - ein Rattenmodell für Rhinosinusitis-Kopfschmerzen / Michael Koch ; Gutachter: Christian Alzheimer ; Betreuer: Karl Meßlinger." Erlangen : Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), 2021. http://d-nb.info/1240479956/34.
Full textNiederführ, Andrea. "Untersuchungen zur mikrobiellen Besiedlung der Nasenhöhle von Patienten mit chronischer Rhinosinusitis unter besonderer Berücksichtigung von Staphylococcus aureus und Staphylococcus aureus Small Colony Varianten." Diss., lmu, 2009. http://nbn-resolving.de/urn:nbn:de:bvb:19-97282.
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