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Relevant bibliographies by topics / Reversed phase chromatography

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Academic literature on the topic 'Reversed phase chromatography'

Author: Grafiati

Published: 4 June 2021

Last updated: 19 February 2022

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Journal articles on the topic "Reversed phase chromatography"

1

Hanai, Toshihiko. "Quantitative Explanation of Retention Mechanisms in Reversed-phase Mode Liquid Chromatography, and Utilization of Typical Reversed-phase Liquid Chromatography for Drug Discovery." Current Chromatography 6, no. 1 (September 18, 2019): 52–64. http://dx.doi.org/10.2174/2213240606666190619120733.

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The retention mechanism in reversed-phase liquid chromatography was quantitatively described using log P (octanol-water partition coefficient). The hydrophobic (lipophilic) interaction liquid chromatography was then used to measure the hydrophobicity of a variety of compounds. Furthermore, the technique has been used as an analytical method to determine molecular properties during the drug discovery process. However, log P values cannot be applied to other chromatographic techniques. Therefore, the direct calculation of molecular interactions was proposed to describe the general retention mechanisms in chromatography. The retention mechanisms in reversed-phase liquid chromatography were quantitatively described in silico by using simple model compounds and phases. The competitive interactions between a bonded-phase and a solvent phase clearly demonstrated the retention mechanisms in reversed-phase liquid chromatography. Chromatographic behavior of acidic drugs on a pentyl-, an octyl-, and a hexenyl-phase was quantitatively described in the in silico analysis. Their retention was based on their hydrophobicity, and hydrogen bonding and electrostatic interaction were selectivity of the hexenyl-phase. This review focuses on the quantitative explanation of the retention mechanisms in reversed-phase liquid chromatography and the practical applications in drug discovery.

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Figge, H., A. Deege, J. Köhler, and G. Schumburg. "Stationary phases for reversed-phase liquid chromatography." Journal of Chromatography A 351 (January 1986): 393–408. http://dx.doi.org/10.1016/s0021-9673(01)83517-2.

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Le Mapihan, K., J. Vial, and A. Jardy. "Reversed-phase liquid chromatography testing." Journal of Chromatography A 1088, no. 1-2 (September 2005): 16–23. http://dx.doi.org/10.1016/j.chroma.2005.02.023.

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4

Cong, Jing Xiang, Shao Yan Wang, and Hong Gao. "Separation of Liquiritin by Two-Dimensional Liquid Chromatography." Advanced Materials Research 455-456 (January 2012): 1232–38. http://dx.doi.org/10.4028/www.scientific.net/amr.455-456.1232.

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Two-dimensional liquid chromatography (2DLC) is an important technology for the separation and analysis of complex samples. Liquiritin, an important active component in licorice, was chosen as the target compound and it was separated by three kinds of off-line 2DLC, i.e. size exclusion chromatography × reversed phase chromatography, normal phase × reversed phase chromatography and reversed phase chromatography × reversed phase chromatography (SEC×RP, NP×RP and RP×RP). The chromatographic conditions were selected and the 2D systems were combined. The results show that it is feasible to separate Liquiritin from licorice extract using 2DLC. Among the 2D modes mentioned above, the highest purity of Liquiritin was obtained in the RP×RP mode, and the concentration of Liquiritin was increased most significantly in the NP×RP mode.

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Melander, W. R., B. K. Chen, and Cs Horváth. "Mobile phase effects in reversed-phase chromatography." Journal of Chromatography A 318 (January 1985): 1–10. http://dx.doi.org/10.1016/s0021-9673(01)90659-4.

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6

Hernandez-Torres, Maria A., John S. Landy, and John G. Dorsey. "Reversed micellar mobile phases for normal-phase chromatography." Analytical Chemistry 58, no. 4 (April 1986): 744–47. http://dx.doi.org/10.1021/ac00295a020.

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Molíková, Martina, and Pavel Jandera. "Characterization of stationary phases for reversed-phase chromatography." Journal of Separation Science 33, no. 4-5 (February 2, 2010): 453–63. http://dx.doi.org/10.1002/jssc.200900699.

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8

Tsuchiya, Yoshiteru. "Reversed-phase high-performance liquid chromatography." Japan journal of water pollution research 11, no. 2 (1988): 83–89. http://dx.doi.org/10.2965/jswe1978.11.83.

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9

Sentell, Karen B., and John G. Dorsey. "Retention mechanisms in reversed-phase chromatography." Journal of Chromatography A 461 (January 1989): 193–207. http://dx.doi.org/10.1016/s0021-9673(00)94287-0.

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Petrović, S. M., and S. Lomić. "Selectivity in Reversed-Phase Liquid Chromatography." Journal of Liquid Chromatography 12, no. 1-2 (January 1989): 59–75. http://dx.doi.org/10.1080/01483918908049190.

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Dissertations / Theses on the topic "Reversed phase chromatography"

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Cowen, Thomas. "Some studies in reversed phase liquid chromatography." Thesis, University of Salford, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.305175.

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Power, Gillian Mary. "The study of chromatographic interactions using model reversed-phase chromatography surfaces." Thesis, University of Nottingham, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.285643.

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3

Waichigo, Martin M. "Alkylammonium Carboxylates as Mobile Phases for Reversed-Phase Liquid Chromatography." Miami University / OhioLINK, 2005. http://rave.ohiolink.edu/etdc/view?acc_num=miami1134142423.

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Shalliker, Ross Andrew, and mikewood@deakin edu au. "Studies on the behaviour of polystyrene in reversed phase chromatography." Deakin University. School of Sciences, 1992. http://tux.lib.deakin.edu.au./adt-VDU/public/adt-VDU20051125.112118.

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Polystyrene behaviour in reversed phase high performance liquid chromatography was influenced mainly by the solvent system, but secondary affects were observed depending on the stationary phase. A variety of reversed phase columns were investigated using mobile phase combinations of dichlorom ethane-methanol, dichloromethane-acetonitrile, ethyl acetate-methanol and ethyl acetate-acetonitrile. Several different modes of behaviour were observed depending on the polymer solubility in the solvent system. In the dichloromethane-methanol solvent system, polymer-stationary phase interactions only occurred when the molecules had pore access. Retention of excluded polystyrene depended on the kinetics of precipitation and redissolution of the polymer. Peak splitting and band broadening occurred when the kinetics were slow and molecular weight separations were limited !o oligomers and polystyrenes lower than 5-10(4) dalton. Excellent molecular weight separations of polystyrenes were obtained using gradient elution reversed phase chromatography with a dichloromethane-acetonitrile mobile phase on C18 columns. The retention was based on polymer-stationary phase interactions regardless of the column pore size. Separations were obtained on large diameter pellicular adsorbents that were almost as good as those obtained on porous adsorbents, showing that pore access was not essential for the retention of high molecular weight polystyrenes. In the best example, the separation ranged from the monomer to 10(6) dalton in a single analysis. Very little adsorption of excluded polymers was observed on C8 or phenyl columns. Polystyrene molecular weight separations to 7-10(5) dalton were obtained in an ethyl acetate-acetonitrile solvent system on C18 columns. Adsorption was responsible for retention. When an ethyl acetate-methanol solvent system was used, no molecular weight separations were obtained because of complex peak splitting. Reversed phase chromatography was compared to size exclusion chromatography for the analysis of polydisperse polystyrenes. Similar results were obtained using both methods. However, the reversed phase method was less sensitive to concentration effects and gave better resolution.

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Torrellas-Hidalgo, Luzmila. "EFFECTS OF ETHANOL/WATER MOBILE PHASES ON REVERSED-PHASE LIQUID CHROMATOGRAPHY." Thesis, The University of Arizona, 1985. http://hdl.handle.net/10150/275466.

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6

El-Rjoob, Abdul-Wahab. "Dynamic stationary phase modification in reversed-phase high performance liquid chromatography /." free to MU campus, to others for purchase, 1996. http://wwwlib.umi.com/cr/mo/fullcit?p9720536.

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Sabharwal, Arvind. "Preparative reversed-phase high performance liquid chromatography of proteins." Thesis, University of Cambridge, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.361678.

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8

Watson, Richard Charles. "Studies of reversed phase high performance liquid chromatography (RP-HPLC) stationary phases." Thesis, University of Nottingham, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.338492.

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Grossman, Shau. "Methylammonium Formate as a Mobile Phase Modifier for Reversed Phase Liquid Chromatography." Miami University / OhioLINK, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=miami1217890628.

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Sexton, Danessa Leann. "Determination of lactose by reversed-phase high performance liquid chromatography." [Johnson City, Tenn. : East Tennessee State University], 2004. http://etd-submit.etsu.edu/etd/theses/available/etd-0328104-212023/unrestricted/SextonD041504f.pdf.

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Thesis (M.S.)--East Tennessee State University, 2004.
Title from electronic submission form. ETSU ETD database URN: etd-0328104-212023. Includes bibliographical references. Also available via Internet at the UMI web site.

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Books on the topic "Reversed phase chromatography"

1

Claessens, Henk A. Characterization of stationary phases for reversed-phase liquid chromatography. Eindhoven: University of Eindhoven, 1999.

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2

Cowen, Thomas. Some studies in reversed phase liquid chromatography. Salford: University of Salford, 1991.

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3

Jaison, P. G. Rapid separation of lanthanides by reversed phase high performance liquid chromatography. Mumbai: Bhabha Atomic Research Centre, 2001.

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4

Kuronen, Pirjo. Development of a retention index monitoring method for reversed-phase high-performance liquid chromatography of non-phosphorus chemical warfare agents. Helsinki: Suomalainen Tiedeakatemia, 1990.

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5

Szepesi, Gábor. How to use reverse-phase HPLC. New York, N.Y: VCH Publishers, 1992.

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6

Garba, Abdu. Reverse-phase high performance liquid chromatography of some group (III) oxinates. Salford: University of Salford, 1985.

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7

Barnes, Karen Wink. The synthesis and characterization of reversed phase stationary phases for high performance liquid chromatography. 1986.

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8

Ying, Peter Tai Yuen. Solute-solvent interaction free energies and retentivity of reversed phase liquid chromatography columns. 1989.

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9

D, Mountain R., and National Institute of Standards and Technology (U.S.), eds. A molecular dynamics study of a reversed-phase liquid chromatography model. Gaithersburg, MD: U.S. Dept. of Commerce, Technology Administration, National Institute of Standards and Technology, 1998.

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10

Kim, Billy. Preparative purification of chemotactic peptides by gradient elution in reversed-phase chromatography. 1997.

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Book chapters on the topic "Reversed phase chromatography"

1

Cox, Geoffrey B. "Preparative Reversed-Phase Chromatography of Proteins." In Chromatography in Biotechnology, 165–82. Washington, DC: American Chemical Society, 1993. http://dx.doi.org/10.1021/bk-1993-0529.ch012.

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2

Smith, Roger M. "Retention Indices in Reversed-Phase HPLC." In Advances in Chromatography, 277–319. Boca Raton: CRC Press, 2021. http://dx.doi.org/10.1201/9781003209027-7.

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3

Forss, Kaj, Raimo Kokkonen, and Pehr-Erik Sågfors. "Reversed-Phase Chromatography of Lignin Derivatives." In ACS Symposium Series, 177–88. Washington, DC: American Chemical Society, 1989. http://dx.doi.org/10.1021/bk-1989-0397.ch013.

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4

Kusebauch, Ulrike, Joshua McBee, Julie Bletz, Richard J. Simpson, and Robert L. Moritz. "Peptide Purification by Reversed-Phase Chromatography." In Amino Acids, Peptides and Proteins in Organic Chemistry, 519–48. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, 2011. http://dx.doi.org/10.1002/9783527631803.ch15.

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5

Hodges, R. S., T. W. L. Burke, A. J. Mendonca, and C. T. Mant. "Preparative Reversed-Phase Sample Displacement Chromatography of Peptides." In Chromatography in Biotechnology, 59–76. Washington, DC: American Chemical Society, 1993. http://dx.doi.org/10.1021/bk-1993-0529.ch005.

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6

Hearn, Milton T. W. "Ion-Pair Chromatography on Normaland Reversed-Phase Systems." In Advances in Chromatography, 59–100. Boca Raton: CRC Press, 2021. http://dx.doi.org/10.1201/9781003209942-2.

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7

SITRIN, R. D., G. CHAN, P. DEPHILLIPS, J. DINGERDISSEN, J. VALENTA, and K. SNADER. "Preparative Reversed Phase High Performance Liquid Chromatography." In ACS Symposium Series, 71–89. Washington, D.C.: American Chemical Society, 1985. http://dx.doi.org/10.1021/bk-1985-0271.ch004.

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8

Pettersson, Sylvia Winkel. "High-Resolution Reversed-Phase Chromatography of Proteins." In Methods of Biochemical Analysis, 135–64. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2011. http://dx.doi.org/10.1002/9780470939932.ch5.

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9

Allenmark, S. G. "Protein Column-Based Chiral Reversed-Phase Liquid Chromatography." In ACS Symposium Series, 114–25. Washington, DC: American Chemical Society, 1991. http://dx.doi.org/10.1021/bk-1991-0471.ch006.

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10

Jinno, Kiyokatsu, and Kazuya Kawasaki. "Microcomputer-Assisted Retention Prediction in Reversed-Phase Liquid Chromatography." In ACS Symposium Series, 167–87. Washington, DC: American Chemical Society, 1986. http://dx.doi.org/10.1021/bk-1986-0297.ch010.

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Conference papers on the topic "Reversed phase chromatography"

1

Liu, Jikun, Chien-Fu Chen, Chien-Cheng Chang, and Don L. DeVoe. "Isoelectric Focusing-Reversed Phase Liquid Chromatography Polymer Microchip With Integrated High-Pressure Valves." In ASME 2009 International Mechanical Engineering Congress and Exposition. ASMEDC, 2009. http://dx.doi.org/10.1115/imece2009-12147.

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A cyclicolefin polymer (COP) microchip supporting parallel 2-D peptide separations is described. By combining isoelectric focusing (IEF) as a first dimension and parallel reversed-phase liquid chromatography (RPLC) as a second dimension, the system enables efficient high-throughput fractionation prior to mass spectrometry in support of peptide mass fingerprinting for global proteomic analysis from highly limited specimens. The IEF-RPLC chip incorporates high-pressure micro shut-off valves, allowing uniform sample transfer and gradient elution from each micro LC column, and ensuring hydrodynamic isolation between the separation dimensions. The utility of the initial microchip is demonstrated by separation of a fluorescein labeled bovine serum albumin tryptic digest in a chip containing a five channel RPLC array.

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2

PENG, MIJUN, CHUNSHAN ZHOU, and SHI-AN ZHONG. "PREPARATIVE SEPARATION OF IRIDOID GLYCOSIDES FROM EUCOMMIA ULMOIDES OLIV. BY REVERSED-PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY." In Proceedings of the 4th International Conference. WORLD SCIENTIFIC, 2004. http://dx.doi.org/10.1142/9789812702623_0097.

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Wang, Yun, Yahui Liu, Song Lu, Yujuan Li, Yongqian Zhang, Hong Qing, and Yulin Deng. "Nano-flow multidimensional liquid platform using strong ion-exchange and reversed-phase chromatography for improved proteomic analyses." In 2015 IEEE International Conference on Mechatronics and Automation (ICMA). IEEE, 2015. http://dx.doi.org/10.1109/icma.2015.7237582.

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Liu, J., C. C. Chen, C. C. Chang, and D. L. DeVoe. "ISOELECTRIC FOCUSING – MULTIPLEXED REVERSED PHASE LIQUID CHROMATOGRAPHY – MALDI-TOF MASS SPECTROMETRY IN A MICROVALVE-INTEGRATED POLYMER CHIP." In 2010 Solid-State, Actuators, and Microsystems Workshop. San Diego: Transducer Research Foundation, 2010. http://dx.doi.org/10.31438/trf.hh2010.116.

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de Vries, J. X., R. Raedsch, A. Stiehl, U. Voelker, I. Walter-Sack, and E. Weber. "EVIDENCE FOR BIIIARY EXCRETION OF PHENPROCOUMON AND ITS METABOLITES IN HUMANS; IDENTIFICATION BY HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY AND GAS CHROMATOGRAPHY-MASS SPECTROMETRY." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643272.

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Recently it has been shown that in man the oral couma-rin anticoagulant phenprocoumon is eliminated up to 60-70 % in urine and 30-40 % in faeces; in urine phenprocoumon (PH) and its metabolites 7-hydroxy-(7-OH),6-hydroxy-(6-OH) and 4'-hydroxy-(4'-OH) phenprocoumon are present mainly as conjugates. No data so far were available on the biliary excretion of these compounds.We examined bile obtained from four in-patients during PH treatment; bile samples were aspirated in the duodenum at the papilla during routine diagnostic endoscopy and immediately deep frozen before analysis. Samples were extracted both untreated as well as after hydrolysis with 6-glucuronidase/aryl sulfatase and separated by reversed phase gradient elution high performance liquid chromatography (HPLC) with fluorescence detection; for confirmation, the same extracts were methylated and analysed by gas chromatography-mass spectrometry (CG-MS) (J.X.de Vries et al J Chromatogr., 338 (1985) 325). PH, 7-OH, 6-OH and 4'-OH were identified by comparison with synthetic authentic samples'''''''

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Medeiros, Ingrid, Hilton Nascimento, Eduardo Gomes, Melissa Premazzi, Jaline Silvério, Erica Fonseca, and Daniel Guedes Jr. "Optimization of high performance liquid chromatography by size exclusion and reversed phase for homogeneity analysis of recombinant human erythropoietin." In I Seminário Anual Científico e Tecnológico em Imunobiológicos. Instituto de Tecnologia em Imunobiológicos, 2013. http://dx.doi.org/10.35259/isi.sact.2013_27331.

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7

Lukasiewicz, Marcin, and Piotr Jakubowski. "Determination of Complexation Parameters for β-Cyclodextrin and Randomly Methylated β-Cyclodextrin Inclusion Complexes of p-Cumaric Acid Using Reversed-Phase Liquid Chromatography." In The 18th International Electronic Conference on Synthetic Organic Chemistry. Basel, Switzerland: MDPI, 2014. http://dx.doi.org/10.3390/ecsoc-18-b028.

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8

Liu, Guoqin, and Lukai Ma. "Simultaneous Analysis of Malondialdehyde, 4-hydroxy-2-hexenal, and 4-hydroxy-2-nonenal in Vegetable Oil by Reversed-phase High-performance Liquid Chromatography." In Virtual 2021 AOCS Annual Meeting & Expo. American Oil Chemists’ Society (AOCS), 2021. http://dx.doi.org/10.21748/am21.486.

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9

Müller, E., A. Henschen, and G. Wunderer. "IDENTIFICATION OF A NEW HUMAN KININ, ILE-SER-BRADYKININ, BY HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY AND SEQUENCE ANALYSIS IN OVARIAN CARCINOMA ASCITES." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1642848.

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Human blood has been shown to contain two different kinin precursors, i.e0 the high and the low molecular mass kininogen0 These two kininogens release the same kinins, with the starting sequences Met-Lys-Arg-Pro-, Lys-Arg-Pro- or just Arg-Pro-depending on the releasing enzyme. The kinin starting with Arg-Pro- is denoted as bradykinin. In rats a different kininogen, called T-kininogen, is also present, especially as the major acute-phase protein in this species. The corresponding kinin, T-kinin, has the starting sequence Ile-Ser-Arg-Pro-. This type of kininogen or kinin has previously never been detected in human tissues. However, during the course of the present study evidence for existance of a third human kininogen, giving rise to human T-kinin, was obtained.Ascites from patients with metastatic ovarian carcinoma has been shown to contain high amounts of vascular permeability-increasing activity as determined by a rat skin-Evans blue test. When the ascites was fractionated by gel filtration followed by reversed-phase high-performance liquid chromatography (HPLC) a component could be isolated which by its total sequence and amino acid composition was identified as Ile-Ser-bradykinin. Several degradation products of this kinin were also detected as separate components in the chromatographies. The human Ile-Ser-bradykinin appeared on reversed-phase HPLC in the same position as synthetic T-kinin. It could be differentiated in this chromatography system from Met-Lys-bradykinin, Lys-bradykinin and bradykinin. It may be assumed that human Ile-Ser-bradykinin is released_ from a third, so far unidentified human kininogen which is only or predominantly expressed under certain pathophysiological conditions, and that therefore this new kinin might be employed as a tumor marker.

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Kaudewitz, H., A. Henschen, and R. E. Zimmermann. "ON THE IDENTITY OF PLATELET FIBRINOGEN WITH PLASMA FIBRINOGEN." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1642934.

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It is a well established fact that fibrinogen occurs not only in blood plasma but also in the α-granules of the platelets. Recently, it has been shown that fibrinogen is synthesised in the megakaryocytes as well as in the liver. Plasma fibrinogen is derived from the liver, but platelet fibrinogen either exclusively or partially from the megakaryocytes. Conclusive, proteinche-mical evidence for the identity of the fibrinogens from the two biosynthetic sources has previously not been produced. However, the two fibrinogen preparations have been shown to have the same overall peptide chain composition, to be thrombin-clottable and release fibrinopeptides of A- and B-type, and to react with antibodies against plasma fibrinogen. The two preparations differ in the way that platelet fibrinogen lacks the higher-molecular-mass γ-chain variant.The aim of the present investigation was to conduct a detailed proteinchemical comparison between human plasma and platelet fibrinogen. For this purpose, fibrin(ogen)s from the two sources were mercaptolysed, alkylated and the three peptide chains isolated by reversed-phase high-performance liquid chromatography (HPLC). The peptide chains were then analysed directly for amino-terminal sequence and for carboxyterminal sequence by isolation of a terminal fragment. The HPLC-fingerprint patterns of the cyanogen bromide-cleaved chains were compared. The native fibrinogens were also treated with thrombin and the fibrinopeptide type distribution determined by reversed-phase HPLC. The carbohydrate side chain compositions were established by ion-exchange-chromatographic methods after acid hydrolysis. So far no previously unrecognized differences have been observed.

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Reports on the topic "Reversed phase chromatography"

1

Slusher, Joseph T., and Raymond D. Mountain. A molecular dynamics study of a reversed-phase liquid chromatography model. Gaithersburg, MD: National Institute of Standards and Technology, 1998. http://dx.doi.org/10.6028/nist.ir.6222.

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2

Shepodd, Timothy J., and Christopher P. Stephens. Development of porous polymer monoliths for reverse-phase chromatography of proteins. Office of Scientific and Technical Information (OSTI), September 2003. http://dx.doi.org/10.2172/918341.

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3

Carr, J. W., and J. M. Harris. Temperature-Induced Changes in Reversed-Phase Chromatographic Surfaces: C8 and C9 Polymeric Ligands. Fort Belvoir, VA: Defense Technical Information Center, July 1988. http://dx.doi.org/10.21236/ada197443.

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