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1

Rodrigo, Juan P., Jose A. Fernandez, Juan C. Alvarez, Justo Gómez, and Carlos Suárez. "Castleman's disease restricted to the infratemporal fossa." Journal of Laryngology & Otology 110, no. 9 (September 1996): 896–98. http://dx.doi.org/10.1017/s0022215100135285.

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AbstractGiant lymph node hyperplasia (Castleman's disease) is usually reported as a solitary mediastinal tumour, although involvement of other anatomical sites and a multicentric form have been reported. We describe a rare case of Castleman's disease due to its localisation (the left infratemporal fossa) and histology (plasma-cell variant). A brief review of the main clinico-histological characteristics of Castleman's disease is also presented.
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2

MacDougall, A. S., and J. A. Loo. "Predicting occurrences of geographically restricted rare floral elements with qualitative habitat data." Environmental Reviews 10, no. 3 (September 1, 2002): 167–90. http://dx.doi.org/10.1139/a02-005.

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Habitat-directed survey methods are often used for locating narrowly distributed rare species and communities across landscapes, though their predictive accuracy varies, depending on the element targeted and the type of data employed. We discuss habitat-directed surveys for rare floral elements in the context of landscape-level management planning, focusing in particular upon a case study from southern New Brunswick. Databases of rare species and community occurrences are important requisites for such planning, but existing information is usually deficient and expensive to develop. A habitat-based approach directs surveys to sites with a higher-than-random probability of hosting rare elements and avoids areas deemed unlikely to be of interest due to environment or disturbance factors. We describe a four-part survey procedure that uses readily available qualitative habitat descriptions and geographic information systems (GIS) based land resource data to identify sites potentially hosting rare biota. The procedure includes remote-sensed and on-site screening to confirm significance and collect ancillary data needed for conservation planning. The use of existing data is cost and time efficient, a necessity given often narrow planning windows and restricted budgets. The method described here is well suited to geographically restricted plant biota associated with distinct habitats, especially in unsurveyed or highly fragmented landscapes. However, the approach does not apply to species of wide-ranging and environmentally heterogeneous habitats. As well, by targeting only highly specific locations assumed to be "optimal" habitat, the occurrence of rare biota in other areas cannot be definitively determined and some sites will almost certainly be missed. The limitations of the procedure highlight the need for multifaceted biodiversity assessment over large areas.Key words: ecosystem management, rare species, gap analysis, habitat-directed biodiversity survey, reserve network, New Brunswick.
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3

Zeng, Ping, and Ting Wang. "Bootstrap Restricted Likelihood Ratio Test for the Detection of Rare Variants." Current Genomics 16, no. 3 (April 9, 2015): 194–202. http://dx.doi.org/10.2174/1389202916666150304234203.

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4

Liu, G. K., H. Z. Zhuang, and X. Y. Chen. "Restricted Phonon Relaxation and Anomalous Thermalization of Rare Earth Ions in Nanocrystals." Nano Letters 2, no. 5 (May 2002): 535–39. http://dx.doi.org/10.1021/nl0255303.

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5

Woodruff, Matthew Charles, Eui Ho Kim, Wei Luo, and Bali Pulendran. "B Cell Competition for Restricted T Cell Help Suppresses Rare-Epitope Responses." Cell Reports 25, no. 2 (October 2018): 321–27. http://dx.doi.org/10.1016/j.celrep.2018.09.029.

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6

Rutherford, Susan, Marlien van der Merwe, Peter G. Wilson, Robert M. Kooyman, and Maurizio Rossetto. "Managing the risk of genetic swamping of a rare and restricted tree." Conservation Genetics 20, no. 5 (June 7, 2019): 1113–31. http://dx.doi.org/10.1007/s10592-019-01201-4.

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7

Labh, RK, and AK Sharma. "Ptosis: a rare presentation of ocular cysticercosis." Nepalese Journal of Ophthalmology 5, no. 1 (March 26, 2013): 133–35. http://dx.doi.org/10.3126/nepjoph.v5i1.7842.

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Background: Cysticercosis is a common parasitic infection involving multiple systems and caused by Cysticercus cellulosae, the larval form of the cestode, Taenia solium. The humans become infected by ingesting its eggs from contaminated food. Here, we present a case of ocular cysticercosis which presented with mild pain, ptosis, inflammation of upper eyelid and slightly restricted ocular motility. Case: A twelve-year-old girl presented with mild pain, unilateral ptosis and inflammation of the right upper eyelid for seven months. There was no history of diurnal variation and trauma. There was neither protrusion of the eyeball nor any mass was palpable in periorbital area. Visual acuity in both the eyes was normal. Periocular and ocular examination revealed a slightly restricted ocular motility in the right upward gaze and a reduced vertical fissure height a with good levator palpebrae function. The Bell’s phenomenon was good. The magnetic resonance imaging of the orbit showed an intra-conal retro-orbital mass involving the superior rectus muscle of the right eye suggestive of ocular cysticercosis. The orbital sonogram revealed a cystic lesion in the superior rectus muscle with an echogenic intramural nodule. The enzyme-linked immunosorbent assay for serum antibodies against the cysticercus was positive. The ptosis improved with a therapeutic trial of albendazole and oral steroids for 6 weeks. Conclusion: Extra-ocular cysticercosis can be treated with oral steroid and albendazole. Nepal J Ophthalmol 2013; 5(9):133-135 DOI: http://dx.doi.org/10.3126/nepjoph.v5i1.7842
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8

Lunge, Snehal, Pradeep Mahajan, Neeta Gokhale, and Renny Pinto. "Unusal presentation of granuloma annulare restricted over the palms: a rare case presentation." Our Dermatology Online 5, no. 1 (January 11, 2014): 45–47. http://dx.doi.org/10.7241/ourd.20141.10.

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9

Meltzer, R. S., K. W. Jang, K. S. Hong, Y. Sun, and S. P. Feofilov. "Optical dephasing of rare earth ions in mixed crystalline and size-restricted systems." Journal of Alloys and Compounds 250, no. 1-2 (March 1997): 279–86. http://dx.doi.org/10.1016/s0925-8388(96)02523-6.

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10

SEVERNS, PAUL M. "Habitat restoration facilitates an ecological trap for a locally rare, wetland-restricted butterfly." Insect Conservation and Diversity 4, no. 3 (November 11, 2010): 184–91. http://dx.doi.org/10.1111/j.1752-4598.2010.00120.x.

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11

Minkoff, Jeffrey, Steven Stecker, Jose Irizarry, Mitchell Whiteman, and Sherry Woodhouse. "Juxta-articular myxoma: a rare cause of painful restricted motion of the knee." Arthroscopy: The Journal of Arthroscopic & Related Surgery 19, no. 10 (December 2003): e143-e150. http://dx.doi.org/10.1016/j.arthro.2003.10.036.

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12

N., Sunanda. "Large cervical fibroid: a rare case report." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 8, no. 8 (July 26, 2019): 3414. http://dx.doi.org/10.18203/2320-1770.ijrcog20193577.

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Although leiomyomas are the most common pelvic tumors presenting in the reproductive age group, cervical fibroids are rare accounting for 2% of all uterine fibroids. We report a case of 40 year old lady presenting with a firm, non-tender mass of 22-24 weeks size pregnant uterus with restricted mobility. Laparotomy showed a large mass arising from the anterior lip of cervix, with a small uterus pushed posteriorly. Enucleation followed by total abdominal hysterectomy was done. Large cervical fibroids are rare, presenting with surgical difficulties. Careful dissection by expert hands is needed in the management of such cases.
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13

Siles, Lizette, and Robert B. Wallace. "First record of the rare bat Gardnerycteris koepckeae (Gardner & Patton, 1972) (Chiroptera, Phyllostomidae) in Bolivia." Check List 17, no. 1 (January 5, 2021): 1–6. http://dx.doi.org/10.15560/17.1.1.

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The phyllostomid bat Gardnerycteris koepckeae (Gardner & Patton, 1972) was considered endemic to Peru and restrict to only two localities, until it was recently collected in a new locality in Colombia. Now we report G. koepckeae for the first time in Bolivia, based on a specimen collected in a well-preserved montane forest inside the Parque Nacional y Área Natural de Manejo Integrado Madidi. The site of capture is at 2280 m, which is the highest elevational record for the species. Gardnerycteris koepckeae is a rare species restricted to a fragile ecosystem threatened by mining and other changes in land use.
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14

Basu, Tathamay, Anton Jesche, Björn Bredenkötter, Maciej Grzywa, Dmytro Denysenko, Dirk Volkmer, Alois Loidl, and Stephan Krohns. "Magnetodielectric coupling in a non-perovskite metal–organic framework." Mater. Horiz. 4, no. 6 (2017): 1178–84. http://dx.doi.org/10.1039/c7mh00716g.

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15

Elghoul, Naoufal, Mohammed Benchakroun, Azzelarab Bennis, Omar Zaddoug, Ali Zine, Mansour Tanane, and Abdeloihab Jaafar. "A Painless Restricted Motion of the Thumb: What Etiology? About An Uncommon Tumor in Uncommon Localization." Case Reports in Orthopedics 2020 (May 31, 2020): 1–3. http://dx.doi.org/10.1155/2020/5649204.

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Lipomas in fingers are rare and account for less than 1% of all cases. As a type of lipoma, the spindle cell lipoma is exceptional and it presents 1.5% of total adipocyte tumors. Moreover, its localization in the thumb is extremely rare. Only three cases have already been reported in adults; our case constitutes the fourth case, which is about a 61-year-old female who presented since 18 months a mass on the ulnar lateral aspect of the thumb. After clinical and radiological assessments, an entire excisional biopsy of the mass was performed. The histopathological analysis confirmed the spindle cell lipoma of the thumb. At the last follow-up of two years, the patient did well with no recurrence and no restricted motion of the thumb. So, although lipomas of the digit are rare, they should be considered a possible etiology of either painful or mechanic restricted motion of the digit.
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16

Huels, M. A., P. Rowntree, L. Parenteau, and L. Sanche. "Two dimensional band-gap restricted diffusion of negatively charged excitons in rare gas solids." Surface Science 390, no. 1-3 (November 1997): 282–88. http://dx.doi.org/10.1016/s0039-6028(97)00573-6.

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17

Cruz-Reyes, Carolina, and Armando Gamboa-Dominguez. "Her2 Amplification in Gastric Cancer Is a Rare Event Restricted to the Intestinal Phenotype." International Journal of Surgical Pathology 21, no. 3 (April 5, 2013): 240–46. http://dx.doi.org/10.1177/1066896913481055.

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18

Valle, Antonio Carlos F. do, Luiz Carlos Moreira, Rodrigo Almeida-Paes, João S. Moreira, Cláudia V. Pizzini, Mauro de Medeiros Muniz, and Rosely M. Zancopé-Oliveira. "Chronic disseminated histoplasmosis with lesions restricted to the mouth: case report." Revista do Instituto de Medicina Tropical de São Paulo 48, no. 2 (April 2006): 113–16. http://dx.doi.org/10.1590/s0036-46652006000200012.

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We report a rare case of chronic disseminated histoplasmosis with several ulcerated lesions in the oral cavity in an alcoholic patient without human immunodeficiency virus infection, with no detectable signs and symptoms of systemic disease or extraoral manifestations. Histopathological analysis revealed chronic inflammatory process with granulomas containing Histoplasma-like organisms. The isolation of Histoplasma capsulatum provided the definitive diagnosis. Treatment with itraconazole resulted in complete remission of oral lesions. As far we aware, this is the second case report of oral histoplasmosis in an HIV negative patient described in Brazil.
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19

Kancharla, Pragnan, Eshan Patel, Kenneth Hennrick, Sherif Ibrahim, and Mendel Goldfinger. "A Rare Presentation of Biclonal Gammopathy in Multiple Myeloma with Simultaneous Extramedullary Involvement: A Case Report." Case Reports in Oncology 12, no. 2 (July 16, 2019): 537–42. http://dx.doi.org/10.1159/000499902.

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Multiple myeloma is characterized by an abnormal clone of plasma cell infiltration in the bone marrow and presence of a high level monoclonal immunoglobulin (M-protein) in the serum or urine in most cases. The monoclonal protein is usually detected as a discrete band in the gamma globulin region by serum protein electrophoresis. Rarely, it may show a simultaneous presence of two distinct bands, which could be either from a single clone, or two separate clones. We report a very unusual presentation of biclonality with lambda restricted IgG predominant cells from cervical lymph node and kappa restricted IgA cells from the bone marrow simultaneously.
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20

Majewski, Wojciech, Jarosław Stolarski, and Philip J. Bart. "Two Rare Pustulose/spinose Morphotypes of Benthic Foraminifera from Eastern Ross Sea, Antarctica." Journal of Foraminiferal Research 49, no. 4 (October 23, 2019): 405–22. http://dx.doi.org/10.2113/gsjfr.49.4.405.

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Abstract Habitats proximal to grounded ice and below ice shelves are rarely studied for microfossils. A recently described, well-resolved deglaciation record from the Whales Deep Basin of the eastern Ross Sea provided an opportunity to study sub-fossil foraminifera in such settings. Among other foraminiferal taxa, two forms with pustulose/spinose ornamentation were especially important as they were restricted to habitats associated with proximity to the calving front or presence of an ice-shelf. Based on gradation from strongly pustulose/spinose to typical morphologies and existing molecular data, these rarely reported forms are considered to be morphotypes of Globocassidulina biora (Crespin, 1960) and Trifarina earlandi (Parr, 1950). They seemed to flourish in polynya areas near grounding-line and in sub-ice-shelf environments with bottom currents. Their unusual morphologies may be a response to limited food resources. These foraminifera deserve special attention because they appear to be restricted to extreme Antarctic environments and hence are potentially very important for paleoenvironmental reconstructions.
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21

Oliver, E. G. H., and I. M. Oliver. "Four new species of ,Erica (Ericaceae) from Western Cape, South Africa." Bothalia 31, no. 1 (September 17, 2001): 1–8. http://dx.doi.org/10.4102/abc.v31i1.493.

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Four new species of Erica L. from the mountains of Western Cape are described: E. richardii E.G.H.Oliv., rare and localized on quartzite cliffs in the foothills of the Great Swartberg north of Klaarstroom, E. anemodes E.G.H.Oliv., and E. viminalis E.G.H.Oliv., both restricted to the Hex River and adjacent mountains, and E. limnophila E.G.H.Oliv., rare around high altitude marshes in the Wemmershoek and Dutoitskloof Mountains.
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22

Lebas, Eve, Pascale Quatresooz, Jorge E. Arrese, and Arjen F. Nikkels. "Eruptive Seborrheic Keratoses Restricted to Plaque/Patch-Stage Mycosis Fungoides." Case Reports in Dermatology 9, no. 2 (June 8, 2017): 35–39. http://dx.doi.org/10.1159/000471787.

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Eruptive seborrheic keratoses (ESK) are rare in dermatology. They are usually inflammatory in nature and may be encountered as Leser-Trélat sign. ESK may also be simultaneously observed with hepatic angiomas, chemotherapy, segmental neurofibromatosis, HIV or erythrodermic pityriasis rubra pilaris, psoriasis, and drug eruption. ESK may be transient and self-healing. Others recede after successful treatment of the underlying disease. In some instances, seborrheic keratoses may follow an isotopic response and remain strictly restricted to sites of previous eczema, photo-exposition or tattoos. A patient with patch/plaque lesions of classic-type mycosis fungoides (MF) presented sudden ESK that were exclusively limited to the MF lesions. In conclusion, this patient combined an isotopic response and ESK.
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23

Mishra, Ram Kumar. "Diffuse Panbronchiolitis is not Restricted to East Asia—a Mini Literature Review." US Respiratory & Pulmonary Diseases 12, no. 02 (2017): 30. http://dx.doi.org/10.17925/usrpd.2017.12.02.30.

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Diffuse panbronchiolitis (DPB) is a rare inflammatory lung disease, and is well recognized in East Asian countries like Japan, China, Taiwan and Korea. Over the years, sporadic DPB cases have been reported worldwide from other countries. This literature review presents an overview of 48 DPB cases from other regions of the world including the US, European countries and Australia. Identification of DPB cases from different racial groups across the globe indicates toward a need to educate pulmonologists to correctly diagnose and initiate treatment.
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24

Das, Sambhunath, and Balram Airan. "Double Valve Replacement Surgery in a Rare Case of Systemic Sclerosis with Restricted Mouth Opening." Journal of Cardiovascular Medicine and Surgery 2, no. 1 (2016): 25–28. http://dx.doi.org/10.21088/jcms.2454.7123.2116.5.

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25

Ghazizadeh, Maryam, MohammadHasan Samandari, MiladEtemadi Shalamzari, and Hooman Navaei. "Coronoid Hyperplasia (Jacob’s Disease) as a Rare Cause of Restricted Mouth Opening: a Case Report." Dental Hypotheses 11, no. 2 (2020): 62. http://dx.doi.org/10.4103/denthyp.denthyp_61_19.

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26

Benestan, L., K. Fietz, N. Loiseau, P. E. Guerin, E. Trofimenko, S. Rühs, C. Schmidt, et al. "Restricted dispersal in a sea of gene flow." Proceedings of the Royal Society B: Biological Sciences 288, no. 1951 (May 19, 2021): 20210458. http://dx.doi.org/10.1098/rspb.2021.0458.

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How far do marine larvae disperse in the ocean? Decades of population genetic studies have revealed generally low levels of genetic structure at large spatial scales (hundreds of kilometres). Yet this result, typically based on discrete sampling designs, does not necessarily imply extensive dispersal. Here, we adopt a continuous sampling strategy along 950 km of coast in the northwestern Mediterranean Sea to address this question in four species. In line with expectations, we observe weak genetic structure at a large spatial scale. Nevertheless, our continuous sampling strategy uncovers a pattern of isolation by distance at small spatial scales (few tens of kilometres) in two species. Individual-based simulations indicate that this signal is an expected signature of restricted dispersal. At the other extreme of the connectivity spectrum, two pairs of individuals that are closely related genetically were found more than 290 km apart, indicating long-distance dispersal. Such a combination of restricted dispersal with rare long-distance dispersal events is supported by a high-resolution biophysical model of larval dispersal in the study area, and we posit that it may be common in marine species. Our results bridge population genetic studies with direct dispersal studies and have implications for the design of marine reserve networks.
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27

Parajuli, Niraj, Bhaskar MM Kayastha, Rushma Shrestha, Anupama Karki, and Laila Lama. "Generalized Mosaic Neurofibromatosis Type 1: A Rare Case Report." Birat Journal of Health Sciences 3, no. 1 (May 6, 2018): 390–92. http://dx.doi.org/10.3126/bjhs.v3i1.19769.

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Neurofibromatosis (NF) consists of group of genetically inherited disorders all of which is characterized by occurrence of nerve sheath tumors. There are eight different subtypes of neurofibromatosis. Segmental NF, a rare mosaic pattern of NF- type1 (NF1) is diagnosed in individuals who have typical features of NF1 restricted to one part of the body and whose parents are both unaffected. But recently the nomenclature has been changed to mosaic NF. We report a case of neurofibromatosis following the lines of blaschko. To the best of our knowledge, no such case report has been published till date of generalized mosaic NF following lines of blaschko's bilaterally symmetrically. BJHS 2018;3(1)5 :390-392
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28

Law, Eric K. C., Ryan K. L. Lee, Alex W. H. Ng, Deyond Y. W. Siu, and Ho-Keung Ng. "Atypical Intracranial Epidermoid Cysts: Rare Anomalies with Unique Radiological Features." Case Reports in Radiology 2015 (2015): 1–4. http://dx.doi.org/10.1155/2015/528632.

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Epidermoid cysts are benign slow growing extra-axial tumours that insinuate between brain structures, while their occurrences in intra-axial or intradiploic locations are exceptionally rare. We present the clinical, imaging, and pathological findings in two patients with atypical epidermoid cysts. CT and MRI findings for the first case revealed an intraparenchymal epidermoid cyst that demonstrated no restricted diffusion. The second case demonstrated an aggressive epidermoid cyst that invaded into the intradiploic spaces, transverse sinus, and the calvarium. The timing of ectodermal tissue sequestration during fetal development may account for the occurrence of atypical epidermoid cysts.
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29

FRANCISCO-GUTIÉRREZ, ANTONIO, GONZALO CASTILLO-CAMPOS, and JOSÉ GUADALUPE GARCÍA-FRANCO. "A new rare species of Agalinis (Orobanchaceae) from the coast of Veracruz, México." Phytotaxa 349, no. 3 (May 15, 2018): 265. http://dx.doi.org/10.11646/phytotaxa.349.3.7.

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A new species of Agalinis from the state of Veracruz is herein described, illustrated and compared with A. flexicaulis, A. harperi, A. maritima var. grandiflora, and A. peduncularis. This new taxon was found in a single locality in the northern coast of Veracruz, Mexico, near to a mangrove-swamp. Given its highly restricted distribution, this species is considered as endemic, being critically endangered as a consequence of local urbanization.
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30

Das, Snehasis, Naveen Kumar Gaur, Oseen Hajilal Shaikh, and Uday Shamrao Kumbhar. "Feeding gastrostomy stoma site cutaneous myiasis: a rare entity." BMJ Case Reports 14, no. 7 (July 2021): e244352. http://dx.doi.org/10.1136/bcr-2021-244352.

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Infestation of any dead or necrotic tissues by the larvae of flies (maggots) is myiasis. This form of habitation is not restricted to any particular tissues in the body and can occur anywhere. However, myiasis at the surgical stoma site is very rare. We present a 55-year-old woman diagnosed with metastatic carcinoma of the oesophagus who underwent feeding gastrostomy (FG). The patient later presented with worms at the FG site. We removed the FG tube, cleared all the maggots, thoroughly cleaned the wound and placed a new FG tube. Although its occurrences have been reported enough in medical history, there are only two documented cases of percutaneous endoscopic gastrostomy stoma site myiasis. Hence, we present the first case in the literature of cutaneous myiasis around an FG stoma site.
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31

Alt, Ruediger, Thomas Riemer, Oliver Fiehn, Dietger Niederwieser, and Michael Cross. "Evidence for Restricted Glycolytic Metabolism in Primary CD133+ Cells." Blood 106, no. 11 (November 16, 2005): 1726. http://dx.doi.org/10.1182/blood.v106.11.1726.1726.

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Abstract The slow cycling, location and hypoxia-resistance of hematopoietic stem cells are suggestive of a restricted metabolism. We propose that HSC metabolism is adapted to unique metabolic conditions supplied by the stem cell niche, and that a combination of the metabolic and signalling environments acts to support stem cell amplification and to limit it to a narrowly-defined and physiologically rare set of sites. To investigate this possibility, we have established moderate throughput, small scale cultures to examine the metabolic characteristics of primary CD133+ cells isolated from umbilical cord blood. A screen of carbon and energy sources revealed that pyruvate (but neither fatty acids nor amino acids) can replace glutamine as a major substrate. The fact that pyruvate contributes significantly to the cellular metabolism even in the presence of glucose suggests that CD133+ cells employ an unusually low level of glycolysis. Flow cytometric analysis of surface markers before and after culture confirmed that the addition of glucose (0mM, 5mM and 25mM) or insulin (0μg/mL, 4 μg/mL) increased the overall cell yield, but had no effect on the proliferation of early cells (CD133+, CD34+ and c-kit+). In parallel, metabolic profiling of undifferentiated and differentiated FDCPmix cells using gas chromatography and mass spectrometry techniques revealed an accumulation of glucose in the self-renewing (undifferentiated) population. Taken together, these observations suggest that glycolysis makes little contribution to stem cell metabolism, and that hematopoietic stem cells (as has been suggested for germ cells) may instead use glycolytic products supplied by stromal cells. Furthermore, our studies have revealed an unexpected effect of osmolarity on both glucose metabolism and self-renewal, in that an increase in osmolarity from 0,32 Osm/Kg to 0,36 Osm/kg reduced the rate of glucose-dependent proliferation of CD133+ cells without reducing the yield of early (CD133+ CD34+, ckit+) cells. Similarly, both the proportion of self-renewing cells in FDCPmix cultures and the recruitment of these cells to active self-renewal in semi-solid media in a colony forming assay were found to be increased at higher osmolarity. This suggests that high osmolarities suppreses both glycolytic metabolism and proliferation rate, but favour the maintenance of “early” progenitors. Finally, we have applied our assay to test a range of different growth factor combinations (of SCF, Flt3-ligand, TPO, IL3, IL6, IL7, IL11 and TGF-b) in 18% and 1% O2, and found that hypoxia extends markedly the range and magnitude of the proliferation response. Taken together, our results suggest that hematopoietic stem cells are indeed adapted to a rare metabolic microenvironment which includes (but is probably not limited to) low oxygen and glucose concentrations, and that the metabolic environment is likely to influence strongly the response to growth factors. A thorough understanding of stem cell metabolism may therefore provide a basis for more controlled manipulation of HSC in vitro.
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32

Chandran, Sobhana. "Pseudo-Duane’s retraction syndrome: a rare clinical entity." International Journal of Otorhinolaryngology and Head and Neck Surgery 6, no. 7 (June 25, 2020): 1387. http://dx.doi.org/10.18203/issn.2454-5929.ijohns20202802.

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<p class="abstract">Studies of sequelae of isolated medial orbital wall fractures show that the majority of patients with this condition are often asymptomatic, which makes the diagnosis based only on clinical grounds difficult. One of the rare complications of this entity is Pseudo-Duane’s retraction syndrome, which is characterised by horizontal diplopia, restricted abduction with or without limited adduction, accompanied by narrowing of the palpebral fissure, globe retraction and pseudo ptosis on abduction. This is a case report of a 46-year-old female who developed Pseudo-Duane’s retraction syndrome following trauma to her left orbit. She presented with left eye pain, diplopia, horizontal gaze restrictions, left eye ecchymosis and enophthalmos. Careful history taking and thorough ophthalmic examination including forced duction test along with radiological imaging helped clinch this diagnosis. Timely intervention by an endoscopic approach to release the medial rectus muscle entrapped within the fracture resolved the patient’s symptoms.</p>
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33

Sharma, Anil Kumar, Charandeep Singh Gandhoke, Somen Misra, Ashik Ravi, Rakesh Kumar Gupta, and Surendra Kumar Gupta. "Ectopic intraconal orbital meningioma – A rare case report." Surgical Neurology International 12 (June 28, 2021): 305. http://dx.doi.org/10.25259/sni_84_2021.

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Background: Ectopic orbital meningiomas (OM) are a rare subset of OMs which are neither attached to the optic nerve sheath nor to the surrounding bone. Case Description: We report the case of a 65-year-old female who presented with a 1 year history of proptosis followed by visual loss and restricted right eye movements since 3 months. Radiology of the orbits was suggestive of intraorbital, intraconal, and heterogeneous contrast enhancing right eye lesion which was completely excised through supraorbital orbitotomy approach. Intraoperatively, the right optic nerve, though compressed, and displaced inferiorly, was free from the lesion. The final histopathological diagnosis was “Meningioma WHO Grade I.” At 3 months follow-up, patient’s vision in the right eye improved from perception of light positive to 6/12 and there was no evidence of recurrence. Conclusion: Rarity of ectopic OM, total surgical excision with an excellent postoperative visual outcome prompted us to report this case.
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34

Butcher, Ryonen. "New taxa of 'leafless' Tetratheca (Elaeocarpaceae, formerly Tremandraceae) from Western Australia." Australian Systematic Botany 20, no. 2 (2007): 139. http://dx.doi.org/10.1071/sb06015.

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The relationships among rare ‘leafless’ species of Tetratheca Sm. occurring on banded ironstone ranges near Koolyanobbing, Western Australia, and allied, unclassified, populations from Eneabba, Newdegate and the Die Hardy Range have been assessed by molecular characters. These findings, in conjunction with morphological investigations, have identified a new species and two new subspecies from within the ‘T. aphylla group’ and these are formally described here. Tetratheca nephelioides R.Butcher, is geographically restricted to the Eneabba area and has close morphological affinity to T. aphylla F.Muell. Tetratheca aphylla subsp. megacarpa R.Butcher, is restricted to the Newdegate area, some 300 km south of the only known populations of T. aphylla subsp. aphylla in the Helena and Aurora Range. Tetratheca paynterae Alford subsp. cremnobata R.Butcher is restricted to the Die Hardy Range, c. 10 km north-east of the only known population of T. paynterae subsp. paynterae at ‘Windarling’. All of these taxa are recognised as Declared Rare Flora. In the process of updating the existing key to ‘leafless’ species of Tetratheca to include these new taxa, two additional new species were identified from within collections of T. nuda Lindl. These are described here as T. angulata R.Butcher and T. applanata R.Butcher. Images and distribution maps for all taxa are provided.
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35

Woll, Petter, Una Kjällquist, Onima Chowdhury, Rikard Erlandsson, Helen Doolittle, Mtakai Ngara, Kristina Anderson, et al. "Diverse Genetic Lesions In Myelodysplastic Syndromes Originate Exclusively In Rare MDS Stem Cells." Blood 122, no. 21 (November 15, 2013): 4195. http://dx.doi.org/10.1182/blood.v122.21.4195.4195.

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Abstract Background The popular concept that human cancers might be driven by rare self-renewing cancer stem cells (CSCs) has extensive implications for cancer biology and modelling, as well for development of more efficient and targeted therapies. However, experimental support for the existence of distinct and rare CSCs in human malignancies remain contentious, particularly in light of compelling evidence that cancer-propagating cells frequently fail to read out in existing human stem cell assays. Therefore, to unequivocally establish the existence and identity of human CSCs, the challenge is first to identify candidate CSCs, and to establish their unique ability to self-renew and replenish molecularly and functionally distinct non-tumorigenic progeny followed by functional in situ validation within the patients themselves. Methods We have in the hematological malignancy myelodysplastic syndromes (MDS) characterize candidate hematopoietic stem and progenitor stages in the bone marrow of low-intermediate risk MDS patients by flow cytometry. Distinct cell populations were functionally characterised for lineage commitment in standard colony forming cell (CFC) assays, and for self-renewal potential in long-term culture initiating cell (LTC-IC) assays and in immune-deficient (NSG) mice. Moreover, we tracked the cellular origin of all identified somatic genetic lesions identified in each patient by targeted next-generation sequencing of genomic DNA isolated from each purified MDS stem and progenitor cell population. Results In low-intermediate risk MDS patients, regardless whether they were del(5q) (n=19) or non-del(5q) (n=11), we could identify rare but distinct Lin-CD34+CD38-CD90+CD45RA- candidate stem cells, granuclocyte-monocyte progenitors (GMPs) and megakaryocyte-erythroid progenitors (MEPs) with frequencies within total BM similar to that of normal age-matched controls. Global gene expression analysis by RNA sequencing of MDS stem cells, GMPs and MEPs suggested that these are molecularly distinct populations. Myeloid and erythroid gene expression signatures were restricted to the GMPs and MEPs, respectively, whereas a transcriptional stem cell signature was restricted to the MDS stem cells. GMPs and MEPs isolated from del(5q) (n=12) and non-del(5q) (n=8) MDS patients displayed lineage-restricted myeloid and erythroid differentiation potentials, respectively. Self-renewal in LTC-IC assay was restricted exclusively to MDS Lin-CD34+CD38-CD90+CD45RA- stem cells in del(5q) (n=11) and non-del(5q) (n=8) MDS patients. Xenotransplantation into NSG mice also confirmed that only Lin-CD34+CD38-CD90+CD45RA- MDS stem cells have in vivo self-renewal potential, and these experiments also demonstrated their ability to replenish downstream CMPs, GMPs and MEPs, establishing the hierarchical relationship of MDS stem and progenitor cells. Targeted DNA sequencing of 88 genes recurrently mutated in MDS and other myeloid malignancies was pursued to identify somatic genetic lesions within the bulk bone marrow of MDS patients (n=13). In total we identified 30 presumed genetic driver lesions, including del(5q) and mutations in key transcription factors (RUNX1), signalling pathways (JAK2, CSF3R), epigenetic regulators (TET2, ASXL1), apoptosis regulators (TP53), and spliceosome components (SF3B1, SRSF2, U2AF2, SRSF6). Importantly, in support of their unique ability to self-renew and replenish lineage-restricted MDS progenitors, all stable somatic genetic lesions identified could in each MDS patient be backtracked to the rare stem cell population as defined phenotypically by flow cytometry and functionally by LTC-IC or xenograft potential, unequivocally establishing their unique stem cell identity within the malignant clone. Conclusions These findings provide definitive evidence for the existence of rare and distinct stem cells in MDS, a finding with extensive implications for therapeutic strategies in MDS and other cancers whose existence might also strictly depend on the persistence of rare CSCs. MDS stem cells typically acquire multiple driver mutations, together conferring a competitive advantage over normal stem cells, while even in combination failing to inflict self-renewal ability on MDS myelo-erythroid progenitor cells. Disclosures: No relevant conflicts of interest to declare.
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36

Cowie, Ian D., and Gordon P. Guymer. "A new, rare species of Brachychiton from Fish River Station, Northern Territory." Australian Systematic Botany 27, no. 6 (2014): 462. http://dx.doi.org/10.1071/sb15006.

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Brachychiton chrysocarpus Cowie & Guymer from Fish River Station in the north-western part of the Northern Territory is described as a new species. It is compared with B. tuberculatus Guymer and B. xanthophyllus Guymer, but differs especially in the softer finer indumentum, shorter caducous stipules, slender paniculate, open inflorescence, the weakly tuberculate follicles and other characters. It appears to be restricted to Eucalyptus tectifica woodland on slopes of ~17° associated with ferruginous sandstone of the Waterbag Creek formation. Its conservation status is discussed and assessed.
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37

Adam, P., E. Haralambieva, M. Hartmann, Z. Mao, G. Ott, and A. Rosenwald. "Rare occurrence of IgVH gene translocations and restricted IgVH gene repertoire in ocular MALT-type lymphoma." Haematologica 93, no. 2 (February 1, 2008): 319–21. http://dx.doi.org/10.3324/haematol.11950.

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38

Makholela, Tsepang, Herman van der Bank, and Kevin Balkwill. "A preliminary study of allozyme variation in three rare and restricted endemic Barleria greenii (Acanthaceae) populations." Biochemical Systematics and Ecology 31, no. 2 (February 2003): 141–54. http://dx.doi.org/10.1016/s0305-1978(02)00085-6.

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39

Straupe, Inga, Aleksanders Adamovičs, and Dina Romānova. "THE EVALUATION OF THE RESTRICTED NATURE RESERVE „LIELUPE FLOOD-PLAIN MEADOWS”." Environment. Technology. Resources. Proceedings of the International Scientific and Practical Conference 1 (June 18, 2005): 164. http://dx.doi.org/10.17770/etr2005vol1.2147.

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The restricted nature reserve „Lielupe flood-plain meadows” was formed to maintain the natural meadows on the banks of the river Lielupe in the territory of Jelgava town. The varied complex of plant communities are located in meadows of Pilssala, on the Lielupe’s right and left bank and thus the nesting of rare and protected meadow and waterbirds as well as important rest area for migrating birds is determined there. The restricted nature reserve is proposed as Natura 2000 place, too. There are the medium moist, moist and wet meadows in the reserve that are the habitats of EU Habitats directive. The biological value of the Lielupe flood plain meadows are currently being endangered by overgrowing and eutrophication. To provide meadows management for maintaining botanical and ornithological values, the inventory of natural meadows was done and proposals for management were developed.
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40

Rossini, Bernardo, Tetiana Skrypets, Carla Minoia, Angela Maria Quinto, Gian Maria Zaccaria, Cristina Ferrari, Nicola Maggialetti, et al. "Primary, Bilateral and Diffuse Renal Non-Hodgkin’s Lymphoma in a Young Woman Suffering from Turner Syndrome." Journal of Personalized Medicine 11, no. 7 (July 7, 2021): 644. http://dx.doi.org/10.3390/jpm11070644.

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Primary renal lymphoma (PRL) is a rare form of non-Hodgkin’s lymphoma (NHL) restricted to and primarily involving one or both kidneys, with no lymph node extension. It accounts for <1% of extranodal lymphomas, and descriptions in the literature are limited. Here, we describe an unprecedented case of bilateral PRL in a 44-year-old woman with Turner syndrome and discuss both diagnostic and therapeutic issues in the light of the available literature in the field. A personalized approach to this rare disease is necessary.
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41

Defabianis, Patrizia. "Scleroderma: a case report of possible cause of restricted movement of the temporomandibular joint with effects on facial development." Journal of Clinical Pediatric Dentistry 28, no. 1 (September 1, 2004): 33–38. http://dx.doi.org/10.17796/jcpd.28.1.607q556111778521.

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Scleroderma is a rare abnormality in which fibrosis of the skin, subcutaneous tissues and muscle may occur. All forms of scleroderma are rare in childhood: the most common form is localized scleroderma. Localized scleroderma is often benign, but may cause significant deformity, if it occurs on the face or extends across joint surfaces. Structural changes may occur in the osseous tissue and result in mandibular joint restriction (pseudoankylosis) and facial and occlusal disharmonies. This article describes a case of facial linear scleroderma in a nine-year-old child and the treatment performed to minimize consequences on occlusion and face development. Available clinical data will be illustrated.
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42

Omar, Nagham, Tom McCann, Ali I. Al-Juboury, and Sven Oliver Franz. "Petrography and geochemistry of the Middle– Upper Jurassic Banik section, northernmost Iraq – Implications for palaeoredox, evaporitic and diagenetic conditions." Neues Jahrbuch für Geologie und Paläontologie - Abhandlungen 297, no. 2 (August 1, 2020): 125–52. http://dx.doi.org/10.1127/njgpa/2020/0916.

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Lithological, petrographic, and geochemical analysis of the Middle to Upper Jurassic succession (i.e.Sargelu and Naokelekan formations) from northernmost Iraq were undertaken with the aim of providing an updated discussion for their sedimentary and diagenetic histories, as well as examining the evaporation proxies and palaeoredox conditions under which these two formations were deposited. Lithologically, the Sargelu Formation comprises massive dolomites, interbedded with shales, rare cherts and one single limestone bed, whilst the Naokelekan Formation consists of shales overlain by limestones and one single dolomite bed. Petrographic analysis of both formations revealed the presence of rare ostracods, bioclastic fragments as well as calcispheres. Five main microfacies were recognized, including bioclastic wackestone, mudstone, dolorudite, dolarenite and dolo micrite microfacies. The shales comprise clay minerals assemblages (illite/muscovite and kaolinite) with some quartz, alkali feldspar and rare pyrite. The Sargelu Formation was probably deposited in a shallow marine environment. In contrast, the Naokelekan Formation is hypothesized to be deposited in a restricted shallow lagoon environment. Palaeoredox indicators suggest that both formations were accumulated under anoxic conditions, most probably in silled basins where water circulation was restricted. Tectonic activity thus resulted in basin compartmentalization across the region, which also explains the marked differences which are often observed.
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43

Martins, Elisabete Raquel, José Melo-Cristino, and Mário Ramirez. "Evidence for Rare Capsular Switching in Streptococcus agalactiae." Journal of Bacteriology 192, no. 5 (December 18, 2009): 1361–69. http://dx.doi.org/10.1128/jb.01130-09.

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ABSTRACT The polysaccharide capsule is a major antigenic factor in Streptococcus agalactiae (Lancefield group B streptococcus [GBS]). Previous observations suggest that exchange of capsular loci is likely to occur rather frequently in GBS, even though GBS is not known to be naturally transformable. We sought to identify and characterize putative capsular switching events, by means of a combination of phenotypic and genotypic methods, including pulsed-field gel electrophoretic profiling, multilocus sequence typing, and surface protein and pilus gene profiling. We show that capsular switching by horizontal gene transfer is not as frequent as previously suggested. Serotyping errors may be the main reason behind the overestimation of capsule switching, since phenotypic techniques are prone to errors of interpretation. The identified putative capsular transformants involved the acquisition of the entire capsular locus and were not restricted to the serotype-specific central genes, the previously suggested main mechanism underlying capsular switching. Our data, while questioning the frequency of capsular switching, provide clear evidence for in vivo capsular transformation in S. agalactiae, which may be of critical importance in planning future vaccination strategies against this pathogen.
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Yevick, David, and Yong Hwan Lee. "Accelerated rare event sampling: Refinement and Ising model analysis." International Journal of Modern Physics C 28, no. 01 (January 2017): 1750012. http://dx.doi.org/10.1142/s0129183117500127.

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In this paper, a recently introduced accelerated sampling technique [D. Yevick, Int. J. Mod. Phys. C 27, 1650041 (2016)] for constructing transition matrices is further developed and applied to a two-dimensional [Formula: see text] Ising spin system. By permitting backward displacements up to a certain limit for each forward step while evolving the system to first higher and then lower energies within a restricted interval that is steadily displaced toward zero temperature as the computation proceeds, accuracy can be greatly enhanced. Simultaneously, the elements obtained from numerous independent calculations are collected in a single transition matrix. The relative accuracy of this novel method is established through a comparison to a transition matrix procedure based on the Metropolis algorithm in which the temperature is appropriately varied during the calculation and the results interpreted in terms of the distribution of realizations over both energy and magnetization.
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45

Thurman, J. D., J. R. Hailey, A. Turturro, and D. W. Gaylor. "Spontaneous Renal Tubular Carcinoma in Fischer-344 Rat Littermates." Veterinary Pathology 32, no. 4 (July 1995): 419–22. http://dx.doi.org/10.1177/030098589503200412.

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Two of 632 Fischer-344 rats in a food restriction study had spontaneous, bilateral, multicentric renal tubular cell carcinomas. Although there were 104 litters represented in this study, both rats that developed this rare neoplasm were from the same litter. The littermates, one male and one female, were in the food-restricted treatment groups (60% of ad libitum intake) and were 550 and 447 days old, respectively, at death. The probability that the two rare bilateral renal neoplasms occurred by a chance event in littermates is approximately 0.8%. The apparent familial predisposition for development of specific types of neoplasms emphasizes the importance of randomization of individuals into treatment groups and consideration of lineage for rare tumors.
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46

Giacalone, Joseph A., and Genai Greenidge. "China, The World Trade Organization, And The Market For Rare Earth Minerals." International Business & Economics Research Journal (IBER) 12, no. 3 (February 19, 2013): 257. http://dx.doi.org/10.19030/iber.v12i3.7669.

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Rare earth elements (also referred to as rare earth minerals, rare earth metals, green elements, rare earths or simply REEs) are comprised of 17 elements of the periodic table. The metals are often found combined together in ores and must be separated into its individual elements. On the supply side of the market, China is currently the largest producer of rare earth elements in the world, mining at least 90% of total world production. Consequently, many countries around the world rely on imports of these REEs to facilitate production of the various systems and products that are dependent on the rare earth metals as raw materials. With one supplier effectively monopolizing the rare earth industry, this imposes severe supply-chain risks to the producers of products that rely on rare earth minerals. After several actions that have restricted the supply, the United States, the European Union, and Japan have challenged China for violating provisions of its membership in the World Trade Organization. This paper will examine the rare earth industry, Chinas near-monopoly, global supply-chain risks, and strategies to reduce dependence on China, including the invocation of the WTOs dispute resolution process.
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47

Sultana, Wahida, Sufia Nasrin Rita, and SM Anwar Sadat. "Sturge Weber Syndrome- A Rare Congenital Neuro-cutaneous Disease." Update Dental College Journal 5, no. 2 (April 7, 2016): 41–51. http://dx.doi.org/10.3329/updcj.v5i2.27275.

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Sturge Weber Syndrome (SWS) or Encephalotrigeminal Angiomatosis is specifically a rare non hereditary congenital sporadic disorder of elusive etiology. It belongs to a group of disorders collectively known as the phakomatoses (“motherspot” diseases). It has a vast continuum of cutaneous, neurologic, ophthalmic and oral manifestations. It consists of congenital hamartomatous malformations that may affect the eye, skin, and central nervous system (CNS) at different times, characterized by the combination of venous angiomas of leptomeninges, face, jaws and oral soft tissues. The classic pathognomonic features of disease include angioma of the leptomeninges extending to cerebral cortex with ipsilateral angiomatous lesions, unilateral facial nevus after one division of trigeminal nerve and epileptic convulsions. The most characteristic oral manifestation is represented by gingival hemangiomatous lesion usually restricted to ipsilateral maxilla or mandible. We report a case of Sturge Weber Syndrome with its characteristic oral manifestations and review of relevant prevailing literature.Update Dent. Coll. j: 2015; 5 (2): 47-51
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48

Shah, Mukesch J., Jan Kaminsky, and Vassilios I. Vougioukas. "Surgical removal of a symptomatic paracondylar process." Journal of Neurosurgery: Spine 10, no. 5 (May 2009): 474–75. http://dx.doi.org/10.3171/2009.2.spine08461.

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The paracondylar process is a rare congenital abnormality of the craniocervical junction that has been identified as a causative agent for severe headache, neck pain, and restricted head movement. Although conservative treatment is usually sufficient, the authors report the case of a symptomatic paracondylar process in a young patient who required surgical intervention.
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49

Fragoso, Yára Dadalti, Soniza Vieira Alves-Leon, Walter Oleschko Arruda, Margarete de Jesus Carvalho, Elizabeth Regina Comini-Frota, Éber Castro Corrêa, Maria Lucia Brito Ferreira, et al. "Natalizumab adverse events are rare in patients with multiple sclerosis." Arquivos de Neuro-Psiquiatria 71, no. 3 (March 2013): 137–41. http://dx.doi.org/10.1590/s0004-282x2013000300002.

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ObjectiveTo assess the prevalence and the profile of adverse events (AE) of natalizumab in patients with multiple sclerosis (MS).MethodsData collection from neurologists attending to patients with MS at specialized units in Brazil.ResultsData from 103 patients attending the infusion centers of 16 MS units in 9 Brazilian states were included in the study. The total number of infusions was 1,042. Seventy-nine patients (76.7%) did not present any AE. Twenty-four patients (23.3%) presented only mild AE. There were three major AE, including two deaths. These three occurrences, although not necessarily being drug-related, must be taken into consideration.ConclusionThe profile of AEs for natalizumab shows that 97% of patients have none or only mild AE. However, still due to safety worries, the use of this medication should be restricted to MS units under the care of specialized neurologists.
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50

Lloyd, Andrea H., Christopher L. Fastie, and Hilary Eisen. "Fire and substrate interact to control the northern range limit of black spruce (Picea mariana) in Alaska." Canadian Journal of Forest Research 37, no. 12 (December 2007): 2480–93. http://dx.doi.org/10.1139/x07-092.

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Black spruce ( Picea mariana (Mill.) BSP) is a common treeline species in eastern Canada but rare at treeline in Alaska. We investigated fire and substrate effects on black spruce populations at six sites along a 74 km transect in the Brooks Range, Alaska. Our southern sites, on a surface deglaciated >50 000 years ago, had significantly more acidic soils, more black spruce, and higher seed viability than our northern sites, which were deglaciated approximately 13 000 years ago. Despite similar fire history at five of our six sites, postfire recruitment dynamics varied with surface age. Sexual reproduction was vigorous in both postfire and nonfire years in populations on the older surface. On the younger surface, vigorous sexual reproduction was restricted to postfire decades and clonal reproduction by branch layering predominated in nonfire years. At the northernmost site, which was unburned, black spruce reproduced almost exclusively by layering. The species’ northern range limit thus reflects an interaction between fire and substrate: on recently deglaciated surfaces, sexual reproduction is restricted to postfire years. This substrate-induced dependence on fire may restrict the range of black spruce to sites that burn sufficiently often to allow occasional sexual reproduction.
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