Journal articles on the topic 'Resection-intersection'

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1

Lakemond, Ruan, Clinton Fookes, and Sridha Sridharan. "Resection-Intersection Bundle Adjustment Revisited." ISRN Machine Vision 2013 (December 12, 2013): 1–8. http://dx.doi.org/10.1155/2013/261956.

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Bundle adjustment is one of the essential components of the computer vision toolbox. This paper revisits the resection-intersection approach, which has previously been shown to have inferior convergence properties. Modifications are proposed that greatly improve the performance of this method, resulting in a fast and accurate approach. Firstly, a linear triangulation step is added to the intersection stage, yielding higher accuracy and improved convergence rate. Secondly, the effect of parameter updates is tracked in order to reduce wasteful computation; only variables coupled to significantly changing variables are updated. This leads to significant improvements in computation time, at the cost of a small, controllable increase in error. Loop closures are handled effectively without the need for additional network modelling. The proposed approach is shown experimentally to yield comparable accuracy to a full sparse bundle adjustment (20% error increase) while computation time scales much better with the number of variables. Experiments on a progressive reconstruction system show the proposed method to be more efficient by a factor of 65 to 177, and 4.5 times more accurate (increasing over time) than a localised sparse bundle adjustment approach.
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Liu, Shigang, Jiancheng Sun, and Jianwu Dang. "A Linear Resection-Intersection Bundle Adjustment Method." Information Technology Journal 7, no. 1 (December 15, 2007): 220–23. http://dx.doi.org/10.3923/itj.2008.220.223.

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3

Börlin, Niclas. "Comparison of resection–intersection algorithms and projection geometries in radiostereometry." ISPRS Journal of Photogrammetry and Remote Sensing 56, no. 5-6 (August 2002): 390–400. http://dx.doi.org/10.1016/s0924-2716(02)00068-0.

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4

Paláncz, B., and J. L. Awange. "Pareto optimality solution of the multi-objective photogrammetric resection-intersection problem." Earth Science Informatics 6, no. 1 (December 8, 2012): 1–20. http://dx.doi.org/10.1007/s12145-012-0107-x.

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5

Font-Llagunes, Josep M., and Joaquim A. Batlle. "New Method That Solves the Three-Point Resection Problem Using Straight Lines Intersection." Journal of Surveying Engineering 135, no. 2 (May 2009): 39–45. http://dx.doi.org/10.1061/(asce)0733-9453(2009)135:2(39).

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Pereira, Fabio Irigon, Joel Augusto Luft, Gustavo Ilha, and Altamiro Susin. "A Novel Resection–Intersection Algorithm With Fast Triangulation Applied to Monocular Visual Odometry." IEEE Transactions on Intelligent Transportation Systems 19, no. 11 (November 2018): 3584–93. http://dx.doi.org/10.1109/tits.2018.2853579.

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7

Beal, Eliza W., Rittal Mehta, Katiuscha Merath, Diamantis I. Tsilimigras, J. Madison Hyer, Anghela Paredes, Mary E. Dillhoff, Jordan Cloyd, Aslam Ejaz, and Timothy M. Pawlik. "Outcomes After Resection of Hepatocellular Carcinoma: Intersection of Travel Distance and Hospital Volume." Journal of Gastrointestinal Surgery 23, no. 7 (May 8, 2019): 1425–34. http://dx.doi.org/10.1007/s11605-019-04233-w.

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8

Maiborodin, I. V., S. V. Marchukov, and V. I. Maiborodina. "SOME FEATURES OF THE KIDNEY SCAR FORMATION AFTER SURGERY IN THE EXPERIMENT." Novosti Khirurgii 29, no. 3 (July 25, 2021): 275–84. http://dx.doi.org/10.18484/2305-0047.2021.3.275.

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Objective. To study the features of scar formation and structural changes in the remaining renal parenchyma in rats after the kidney resection in various terms. Methods. A layeredclosure of midline laparotomy and the caudal part of the left kidney removal was performed in rats under general inhalation ether anesthesia in a clean operating room. The morphology of the remaining kidney part after resection was studied using light microscope in different terms. Results. Athrombusfrom blood leaking outof the cut vessels is formed on the damaged surface of the kidney immediately after the resection. This clot with the parenchyma is gradually replaced by the connective tissue along the edge of the defect with the subsequently formation of a thin connective or fibrous tissue scar. However, in many cases, the number of which in rats can reach 40%, the processes of kidney damage continue for a long time after surgery, and leading to total or subtotal nephrosclerosis. The detected cystic change in tubular structures, apparently, occurred firstly due to their intersection during the resection, clamping by a blood clot and / or compression by edema distal to the observation site. Then, the forming extensive scar again clamped the adjacent tubular structures with subsequent cystic degeneration and sclerosis. In this case, detritus formed from non-viable renal tissues is eliminated by macrophages, which can form multinucleated cells with fused cytoplasm. Conclusion. Structural changes in the nephrosclerosis progression after kidney resection consist in the gradual replacement of the all renal cortical and medullar parenchyma by the connective tissue. This is not associated with the autoimmune process, but is more likely due to both impaired urine outflow after intercut of the tubular structures at resection and/or compression by edema, inflammatory infiltrate, forming or organizing scar, and vascular disorders associated with these causes. The inflammation accompanying necrosis and sclerosis of the renal structures can become granulomatous. What this paper adds For the first time, it has been shown that the progressively enlarging scar can be formed after the kidney resection, resulting in total nephrosclerosis. Such changes develop both due to the intersection of the tubular structures during the resection and their compression by edema, inflammatory infiltrate, forming or organizing a scar, and vascular disorders due to the above-mentioned causes.
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9

Hänsch, R., I. Drude, and O. Hellwich. "MODERN METHODS OF BUNDLE ADJUSTMENT ON THE GPU." ISPRS Annals of Photogrammetry, Remote Sensing and Spatial Information Sciences III-3 (June 3, 2016): 43–50. http://dx.doi.org/10.5194/isprsannals-iii-3-43-2016.

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The task to compute 3D reconstructions from large amounts of data has become an active field of research within the last years. Based on an initial estimate provided by structure from motion, bundle adjustment seeks to find a solution that is optimal for all cameras and 3D points. The corresponding nonlinear optimization problem is usually solved by the Levenberg-Marquardt algorithm combined with conjugate gradient descent. While many adaptations and extensions to the classical bundle adjustment approach have been proposed, only few works consider the acceleration potentials of GPU systems. This paper elaborates the possibilities of time and space savings when fitting the implementation strategy to the terms and requirements of realizing a bundler on heterogeneous CPUGPU systems. Instead of focusing on the standard approach of Levenberg-Marquardt optimization alone, nonlinear conjugate gradient descent and alternating resection-intersection are studied as two alternatives. The experiments show that in particular alternating resection-intersection reaches low error rates very fast, but converges to larger error rates than Levenberg-Marquardt. PBA, as one of the current state-of-the-art bundlers, converges slower in 50 % of the test cases and needs 1.5-2 times more memory than the Levenberg- Marquardt implementation.
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10

Hänsch, R., I. Drude, and O. Hellwich. "MODERN METHODS OF BUNDLE ADJUSTMENT ON THE GPU." ISPRS Annals of Photogrammetry, Remote Sensing and Spatial Information Sciences III-3 (June 3, 2016): 43–50. http://dx.doi.org/10.5194/isprs-annals-iii-3-43-2016.

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The task to compute 3D reconstructions from large amounts of data has become an active field of research within the last years. Based on an initial estimate provided by structure from motion, bundle adjustment seeks to find a solution that is optimal for all cameras and 3D points. The corresponding nonlinear optimization problem is usually solved by the Levenberg-Marquardt algorithm combined with conjugate gradient descent. While many adaptations and extensions to the classical bundle adjustment approach have been proposed, only few works consider the acceleration potentials of GPU systems. This paper elaborates the possibilities of time and space savings when fitting the implementation strategy to the terms and requirements of realizing a bundler on heterogeneous CPUGPU systems. Instead of focusing on the standard approach of Levenberg-Marquardt optimization alone, nonlinear conjugate gradient descent and alternating resection-intersection are studied as two alternatives. The experiments show that in particular alternating resection-intersection reaches low error rates very fast, but converges to larger error rates than Levenberg-Marquardt. PBA, as one of the current state-of-the-art bundlers, converges slower in 50 % of the test cases and needs 1.5-2 times more memory than the Levenberg- Marquardt implementation.
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11

Diaz, Adrian, Djhenne Dalmacy, J. Madison Hyer, Diamantis Tsilimigras, and Timothy M. Pawlik. "Intersection of social vulnerability and residential diversity: Postoperative outcomes following resection of lung and colon cancer." Journal of Surgical Oncology 124, no. 5 (July 2021): 886–93. http://dx.doi.org/10.1002/jso.26588.

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12

Rennert, Robert C., Reid Hoshide, Mark Calayag, Joanna Kemp, David D. Gonda, Hal S. Meltzer, Takanori Fukushima, John D. Day, and Michael L. Levy. "Extended middle fossa approach to lateralized pontine cavernomas in children." Journal of Neurosurgery: Pediatrics 21, no. 4 (April 2018): 384–88. http://dx.doi.org/10.3171/2017.10.peds17381.

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OBJECTIVETreatment of hemorrhagic cavernous malformations within the lateral pontine region demands meticulous surgical planning and execution to maximize resection while minimizing morbidity. The authors report a single institution’s experience using the extended middle fossa rhomboid approach for the safe resection of hemorrhagic cavernomas involving the lateral pons.METHODSA retrospective chart review was performed to identify and review the surgical outcomes of patients who underwent an extended middle fossa rhomboid approach for the resection of hemorrhagic cavernomas involving the lateral pons during a 10-year period at Rady Children’s Hospital of San Diego. Surgical landmarks for this extradural approach were based on the Fukushima dual-fan model, which defines the rhomboid based on the following anatomical structures: 1) the junction of the greater superficial petrosal nerve (GSPN) and mandibular branch of the trigeminal nerve; 2) the lateral edge of the porus trigeminus; 3) the intersection of the petrous ridge and arcuate eminence; and 4) the intersection of the GSPN, geniculate ganglion, and arcuate eminence. The boundaries of maximal bony removal for this approach are the clivus inferiorly below the inferior petrosal sinus; unroofing of the internal auditory canal posteriorly; skeletonizing the geniculate ganglion, GSPN, and internal carotid artery laterally; and drilling under the Gasserian ganglion anteriorly. This extradural petrosectomy allowed for an approach to all lesions from an area posterolateral to the basilar artery near its junction with cranial nerve (CN) VI, superior to the anterior inferior cerebellar artery and lateral to the origin of CN V. Retraction of the mandibular branch of the trigeminal nerve during this approach allowed avoidance of the region involving CN IV and the superior cerebellar artery.RESULTSEight pediatric patients (4 girls and 4 boys, mean age of 13.2 ± 4.6 years) with hemorrhagic cavernomas involving the lateral pons and extension to the pial surface were treated using the surgical approach described above. Seven cavernomas were completely resected. In the eighth patient, a second peripheral lesion was not resected with the primary lesion. One patient had a transient CN VI palsy, and 2 patients had transient trigeminal hypesthesia/dysesthesia. One patient experienced a CSF leak that was successfully treated by oversewing the wound.CONCLUSIONSThe extended middle fossa approach can be used for resection of lateral pontine hemorrhagic cavernomas with minimal morbidity in the pediatric population.
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13

Fan, Sheng Hong, Chang Ru Liu, Xiao Tong Qi, Lai Wei Jiang, and Ya Jun Wu. "A New 3D Coordinates Acquisition Method on Base of Single Camera." Applied Mechanics and Materials 475-476 (December 2013): 296–300. http://dx.doi.org/10.4028/www.scientific.net/amm.475-476.296.

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As is known to us, conventional photogrammetry uses the double phase stereopair for forward intersection, but this paper proposed a new method for 3D coordinates acquisition based on single camera. Under the defined relationship of the object relative position, three-dimensional coordinates can be obtained by space resection through single photo. The principle of this method is simple but practical, especially suitable for measuring the overall mobile objects. Experiments show that within1500mm, plane normal direction is better than 0.02°in the measurement accuracy , and can replace stereopair measurement in certain conditions for its higher measurement accuracy.
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14

Wang, Wei-Hsin, Kumar Abhinav, Eric Wang, Carl Snyderman, Paul A. Gardner, and Juan C. Fernandez-Miranda. "Endoscopic Endonasal Transclival Transcondylar Approach for Foramen Magnum Meningiomas." Operative Neurosurgery 12, no. 2 (November 3, 2015): 153–62. http://dx.doi.org/10.1227/neu.0000000000001102.

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Abstract BACKGROUND The endoscopic endonasal approach provides a direct route to ventral foramen magnum (FM) lesions like meningiomas, which are difficult to access. Endonasal access at the FM is limited laterally by the occipital condyles and inferiorly by the C1 anterior arch and the odontoid process, which may need partial resection. OBJECTIVE We investigated the surgical anatomy and technical nuances for endonasally increasing the surgical corridor at the FM region both laterally and inferiorly. Unique to our report, we quantified the amount of required medial condyle resection to obtain exposure of the lateral aspects of the FM. METHODS Five fresh human head silicone-injected specimens underwent endonasal inferior transclival, transcondylar approaches. The lateral limit of medial condyle resection was defined using a vertical line extending inferiorly from foramen lacerum and its intersection with the occipital condyle. The condylectomy was limited posteriorly by the cortical bone surrounding the hypoglossal canal. The volume of the resected condyle (cubic centimeters) for 10 sides was measured using the pre- and postdissection computed tomography-volumetric analysis. RESULTS The mean percentage condylar volume resected during a unilateral medial condylectomy was 18% (9.7%-28.3%). The surgical corridor was extended inferiorly in all specimens without violating the transverse ligament by drilling the superior aspects of C1 anterior arch and the exposed odontoid tip. These operative nuances were successfully applied in the operating room. CONCLUSION Anatomical landmarks can reliably guide an endonasal anteromedial condyle resection. Minimal condyle resection is required to widen lateral access at the FM, which minimizes the risk of craniocervical instability.
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15

Ushakova, T. L., E. A. Tuzova, A. D. Shutova, O. V. Gorovtsova, T. G. Gasparyan, A. Kh Bekyashev, and V. G. Polyakov. "Extended surgical interventions in children with retinoblastoma invasion into the optic nerve." Russian Journal of Pediatric Hematology and Oncology 8, no. 2 (July 12, 2021): 50–60. http://dx.doi.org/10.21682/2311-1267-2021-8-2-50-60.

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Introduction. Standard eye enucleation (EE) may not always guarantee a sufficient length of resection of the optic nerve (ON) so that the tumor cells do not spread along the optic nerve at the intersection line. Surgical access and the scope of surgical intervention are determined by the spread and localization of the tumor, as well as the qualification of the operating team.Purpose — to evaluate the role of extended surgical interventions in the spread of extraocular tumors on the ON.Materials and methods. The study included 9 patients with retinoblastoma (RB) and macroinvasion of the ON during primary magnetic resonance imaging (MRI) and/or micromorphological invasion of the ON resection line after EE. 4 of the 9 patients were treated with primary/secondary EE, induction chemotherapy (CT) and high-dose CT (HDCT), radiation therapy (RT). 5 out of 9 patients underwent secondary extended surgical interventions: exenteration of the orbit (n = 1), osteoplastic lateral orbitotomy with precanal resection of the ON (n = 2) in combination with EE in one case, subfrontal craniotomy (n = 1) and orbitozygomatic craniotomy (n = 1) with prechiasmal resection of the ON and EE with adjuvant RT (excluding the latter case) and CT, without HDCT.Results. It should be noted that the overall survival (OS) of 5 patients with complete microscopic resection (R0) after extended secondary operations was 75 ± 0.217 % with an average follow-up period of 77.25 ± 18.8 months, while in 4 patients with R1 (n = 4) without secondary extended operations with HDCT reached only 50 ± 0.25 % with an average follow-up period of 57 ± 24.8 months.Conclusion. MRI is mandatory for the primary diagnosis of RB, especially when there is a risk of the tumor spreading through the ON. Secondary surgery with R0-resection has a positive effect on survival. The need for adjuvant RT and CT after surgery should be discussed.
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Mateoiu1, Petronela Petronela, F. Dumitrache, O. Andronic, Alexandra Bolocan, and D. Ion. "A RARE CASE OF A GIANT RETROPERITONEAL RECURRENT LIPOSARCOMA." Journal of Surgical Sciences 2, no. 3 (July 1, 2015): 128–31. http://dx.doi.org/10.33695/jss.v2i3.121.

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We report the case of a giant retroperitoneal liposarcoma, with two rare histological subtypes: pleomorphic subtype at initial surgical resection, and dedifferentiated subtype at the recurrence. A 61-year-old male patient, presented at the University Emergency Hospital Bucharest, for progressive enlargement of the abdomen. The exploratory laparotomy found a deforming mass in the retroperitoneal area, with medial displacement of the left colon, from the splenic flexure to the recto-sigmoid junction. After assessing the resectability of the tumor, it was decided and performed an en-bloc excision of the tumor, without multiorgan resection and with macroscopic free safety margins. Due to the intersection with the genital vessels, their resection was imposed. The tumor was trefoil-shaped, with a diameter of 35 cm. After 7 months of chemotherapy, tumor recurrence occured, within the same location, confirmed as a dedifferentiated subtype. The same surgical procedure was performed, and the oncologist decided to continue with a more aggressive chemotherapy. Pleomorphic liposarcoma has a high rate of recurrence and has a high resistantce at chemotherapy. Due to its deep retroperitoneal location, the relations with the inferior vena cava, the aorta and the genital vessels are essential, in some cases multiorgan resections being necessary.The case presents a rare malignant tumor, a 35 cm diameter retroperitoneal liposarcoma, highly resistant to chemotherapy and with a high recurrence rate.
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Kalani, M., and William Couldwell. "Extreme Lateral Supracerebellar Infratentorial Approach to the Lateral Midbrain." Journal of Neurological Surgery Part B: Skull Base 79, S 05 (September 25, 2018): S415—S417. http://dx.doi.org/10.1055/s-0038-1669981.

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This video illustrates the case of a 52-year-old man with a history of multiple bleeds from a lateral midbrain cerebral cavernous malformation, who presented with sudden-onset headache, gait instability, and left-sided motor and sensory disturbances. This lesion was eccentric to the right side and was located in the dorsolateral brainstem. Therefore, the lesion was approached via a right-sided extreme lateral supracerebellar infratentorial (exSCIT) craniotomy with monitoring of the cranial nerves. This video demonstrates the utility of the exSCIT for resection of dorsolateral brainstem lesions and how this approach gives the surgeon ready access to the supracerebellar space, and cerebellopontine angle cistern. The lateral mesencephalic safe entry zone can be accessed from this approach; it is identified by the intersection of branches of the superior cerebellar artery and the fourth cranial nerve with the vein of the lateral mesencephalic sulcus. The technique of piecemeal resection of the lesion from the brainstem is presented. Careful patient selection and respect for normal anatomy are of paramount importance in obtaining excellent outcomes in operations within or adjacent to the brainstem.The link to the video can be found at: https://youtu.be/aIw-O2Ryleg.
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Qiang, Zhang, Shen Jian-jing, and Sun Meng-qing. "THE OUTDOOR RAPID CALIBRATION TECHNIQUE AND REALIZATION OF NONMETRIC DIGITAL CAMERA BASED ON THE METHOD OF MULTI-IMAGE DLT AND RESECTION." ISPRS - International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences XLI-B1 (June 3, 2016): 265–69. http://dx.doi.org/10.5194/isprsarchives-xli-b1-265-2016.

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For non-metric CCD digital camera features and the needs of Rapid field non-metric cameras calibration, the error sources was detailed analyzed and a mathematical calibration model has been founded. Both detailed multi-image group iterative method for solving DLT coefficient, the elements of interior orientation and distortion parameters of lens and the multi-image resection method for solving the elements of interior orientation, elements of exterior orientation and distortion parameters of lens have been discussed. A standard steel cage (e.g. Figure 1) has been made for real calibrating non-metric cameras outdoor quickly. In order to verify the accuracy, each method mentioned has been used to solve elements of interior orientation and distortion parameters with the same camera (e.g. Figure 2) and the same test images. The results of accuracy show that the maximum X error was 0.2585mm, the maximum Y error was 0.6719mm and the maximum Z error was 0.1319mm by using multi-image DLT algorithm. On the other hand, the maximum X error was 0.1914mm, the maximum Y error was 0.9808mm and the maximum Z error was 0.1453mm by using multi-image resection algorithm. The forward intersection accuracy of the two methods was quite, and the both were less than 1mm. By using multi-image DLT algorithm the planimetric accuracy was less than 0.2585mm and the height accuracy was less than 0.6719mm. On the other hand, by using multi-image resection algorithm the planimetric accuracy was less than 0.1914mm and the height accuracy was less than 0.9808mm. The planimetric accuracy of resection algorithm was the better than DLT algorithm, but the elevation accuracy of DLT algorithm was the better than resection algorithm. In summary both method can be accepted for nonmetric camera calibration. But also the solver accuracy in the inner orientation elements and distortion parameters was not very high has been noted. However for non-metric camera, the true value of inner orientation elements and lens distortion were unknown did not affect the accuracy of photogrammetry.
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Qiang, Zhang, Shen Jian-jing, and Sun Meng-qing. "THE OUTDOOR RAPID CALIBRATION TECHNIQUE AND REALIZATION OF NONMETRIC DIGITAL CAMERA BASED ON THE METHOD OF MULTI-IMAGE DLT AND RESECTION." ISPRS - International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences XLI-B1 (June 3, 2016): 265–69. http://dx.doi.org/10.5194/isprs-archives-xli-b1-265-2016.

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For non-metric CCD digital camera features and the needs of Rapid field non-metric cameras calibration, the error sources was detailed analyzed and a mathematical calibration model has been founded. Both detailed multi-image group iterative method for solving DLT coefficient, the elements of interior orientation and distortion parameters of lens and the multi-image resection method for solving the elements of interior orientation, elements of exterior orientation and distortion parameters of lens have been discussed. A standard steel cage (e.g. Figure 1) has been made for real calibrating non-metric cameras outdoor quickly. In order to verify the accuracy, each method mentioned has been used to solve elements of interior orientation and distortion parameters with the same camera (e.g. Figure 2) and the same test images. The results of accuracy show that the maximum X error was 0.2585mm, the maximum Y error was 0.6719mm and the maximum Z error was 0.1319mm by using multi-image DLT algorithm. On the other hand, the maximum X error was 0.1914mm, the maximum Y error was 0.9808mm and the maximum Z error was 0.1453mm by using multi-image resection algorithm. The forward intersection accuracy of the two methods was quite, and the both were less than 1mm. By using multi-image DLT algorithm the planimetric accuracy was less than 0.2585mm and the height accuracy was less than 0.6719mm. On the other hand, by using multi-image resection algorithm the planimetric accuracy was less than 0.1914mm and the height accuracy was less than 0.9808mm. The planimetric accuracy of resection algorithm was the better than DLT algorithm, but the elevation accuracy of DLT algorithm was the better than resection algorithm. In summary both method can be accepted for nonmetric camera calibration. But also the solver accuracy in the inner orientation elements and distortion parameters was not very high has been noted. However for non-metric camera, the true value of inner orientation elements and lens distortion were unknown did not affect the accuracy of photogrammetry.
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Maas, H. G. "A MODULAR GEOMETRIC MODEL FOR UNDERWATER PHOTOGRAMMETRY." ISPRS - International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences XL-5/W5 (April 9, 2015): 139–41. http://dx.doi.org/10.5194/isprsarchives-xl-5-w5-139-2015.

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Underwater applications of photogrammetric measurement techniques usually need to deal with multimedia photogrammetry aspects, which are characterized by the necessity of handling optical rays that are broken at interfaces between optical media with different refrative indices according to Snell’s Law. This so-called multimedia geometry has to be incorporated into geometric models in order to achieve correct measurement results. <br><br> The paper shows a flexible yet strict geometric model for the handling of refraction effects on the optical path, which can be implemented as a module into photogrammetric standard tools such as spatial resection, spatial intersection, bundle adjustment or epipolar line computation. The module is especially well suited for applications, where an object in water is observed by cameras in air through one or more plane parallel glass interfaces, as it allows for some simplifications here.
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Grafarend, E., and J. Shan. "Closed form solution to the twin P4P or the combined three dimensional resection-intersection problem in terms of Möbius barycentric coordinates." Journal of Geodesy 71, no. 4 (March 21, 1997): 232–39. http://dx.doi.org/10.1007/s001900050090.

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Azizi, A., H. Afsharnia, and A. Hadavand. "EVALUATION AND ANALYSIS OF A PARAMETRIC APPROACH FOR SIMULTANEOUS SPACE RESECTION-INTERSECTION OF HIGH RESOLUTION SATELLITE IMAGES WITHOUT USING GROUND CONTROL POINTS." ISPRS - International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences XL-1/W3 (September 24, 2013): 61–66. http://dx.doi.org/10.5194/isprsarchives-xl-1-w3-61-2013.

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Nakai, Nozomu, Tomohiro Yamaguchi, Yusuke Kinugasa, Akio Shiomi, Hiroyuki Tomioka, Hiroyasu Kagawa, Yushi Yamakawa, and Sumito Sato. "Laparoscopic Sigmoid Colectomy for a Patient With Sigmoid Colon Cancer and Crossed-Fused Renal Ectopia: A Case Report." International Surgery 100, no. 3 (March 1, 2015): 423–27. http://dx.doi.org/10.9738/intsurg-d-13-00255.1.

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Crossed-fused renal ectopia (CFRE) is a very rare congenital renal malformation. This condition comprises several anatomic anomalies, including unilateral ureteral intersection of the midline, anteriorly-placed renal pelvises, and aberrant renal blood vessels, all of which increase the difficulty of colectomy. This report describes a case of laparoscopic sigmoidectomy with sufficient lymphadenectomy for a patient with sigmoid colon cancer and left-sided L-shaped CFRE. Preoperative computed tomography demonstrated that the origin of the inferior mesenteric artery (IMA) was free from anomalies and that the tumor did not invade surrounding organs. Therefore, we planned conventional laparoscopic sigmoid colectomy with D3 lymphadenectomy. Division of IMA at its origin and anterior colon resection was successfully performed by careful mobilization of the mesocolon to avoid exposing the retroperitoneal organs. To our knowledge, this is the first case report of laparoscopic colectomy for a patient with CFRE. Sufficient preoperative assessment of anatomic anomalies enabled successful surgery.
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Wang, Qian-qian, Chang Tan, Geng Qin, and Shu-kun Yao. "Promising Clinical Applications of Hydrogels Associated With Precise Cancer Treatment: A Review." Technology in Cancer Research & Treatment 22 (January 2023): 153303382211503. http://dx.doi.org/10.1177/15330338221150322.

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Gastrointestinal cancer is one of the most malignant tumors with high morbidity and mortality, especially colorectal cancer, which has become the second leading cause of cancer-related deaths worldwide. Targeted drug treatment and precise endoscopic resection can significantly improve the overall survival rate and greatly extend the life span. Promising biomedical applications of hydrogels would represent hopeful therapeutic alternatives for patients with different kinds of diseases, particularly providing precise therapy for cancer patients. Although the intersection field of material science and biomedical science has made tremendous advances, major challenges remain. In this review, the application of hydrogel-based technology in cancer precision medicine is the focus of attention, which is the development trend of multidisciplinary cooperation in the future. First, we provide the current clinical landscape of hydrogel applications, and then we highlight precision oncology, including personalized drug treatment and accurate endoscopic intervention. Finally, we discuss major challenges for their clinical translation that have not yet been overcome and future perspectives on cancer precision medicine.
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Gautier, S. V., V. K. Konstantinov, Kh M. Khizroev, A. R. Monakhov, T. A. Dzhanbekov, and S. V. Meshcheryakov. "Quality of Life of related liver donors in the late postoperative period." Russian Journal of Transplantology and Artificial Organs 19, no. 1 (April 14, 2017): 6–9. http://dx.doi.org/10.15825/1995-1191-2017-1-6-9.

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Introduction. Quality of life (QoL) is a new promising area of clinical medicine that provides the opportunity to assess the state of health of the patient and to have a notion of the surgery effects based on the parameters which are lying at the intersection of scientific approach of the surgeons and subjective point of view of the patient.Materials and methods. The study included 52 living-related liver fragment donors operated between 2009 and 2014. Donors were surveyed after 2–5 years from the surgery. Comparison group was formed by healthy volunteers, students of the Medical University. The Russian version of the non-specific SF-36 questionnaire was used to assess QoL.Results. Donors in the postoperative period have demonstrated a high level of physical parameter (57.65 ± 3.8). Parameter of psychological health in the postoperative period was (52.01 ± 5.2). These figures are comparable with the results in the comparison group (p > 0.05). All donors have returned to normal life.Conclusions. Overall results of this study were similar to those of the foreign colleagues which confirm the high safety of liver resection surgery and the efficacy of SF-36 questionnaire in the assessment of quality of life of the living-related liver fragment donors.
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Kochi, Nobuo, Sachiko Isobe, Atsushi Hayashi, Kunihiro Kodama, and Takanari Tanabata. "Introduction of All-Around 3D Modeling Methods for Investigation of Plants." International Journal of Automation Technology 15, no. 3 (May 5, 2021): 301–12. http://dx.doi.org/10.20965/ijat.2021.p0301.

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Digital image phenotyping has become popular in plant research. Plants are complex in shape, and occlusion can often occur. Three-dimensional (3D) data are expected to measure the morphological traits of plants with higher accuracy. Plants have organs with flat and/or narrow shapes and similar component structures are repeated. Therefore, it is difficult to construct an accurate 3D model by applying methods developed for industrial materials and architecture. Here, we review noncontact and all-around 3D modeling and configuration of camera systems to measure the morphological traits of plants in terms of system composition, accuracy, cost, and usability. Typical noncontact 3D measurement methods can be roughly classified into active and passive methods. We describe their advantages and disadvantages. Structure-from-motion/multi-view stereo (SfM/MVS), a passive method, is the most frequently used measurement method for plants. It is described in terms of “forward intersection” and “backward resection.” We recently developed a novel SfM/MVS approach by mixing the forward and backward methods, and we provide a brief overview of our approach in this paper. While various fields are adopting 3D model construction, nonexpert users struggle to use them and end up selecting inadequate methods, which lead to model failure. We hope that this review will help users who are considering starting to construct and measure 3D models.
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Gerasimenko, M. Yu, I. S. Evstigneeva, Ch T. Salchak, T. N. Zaitseva, and M. G. Lutoshkina. "Experience in using low-temperature plasma after surgical treatment of breast cancer." Russian Journal of Physiotherapy, Balneology and Rehabilitation 19, no. 3 (January 12, 2021): 195–200. http://dx.doi.org/10.17816/1681-3456-2020-19-3-8.

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Background.Plasma medicine is a new direction in science at the intersection of plasma physics and chemistry with biology and medicine low-temperature plasma (LTP) has a number of fundamental advantages, which include high non-specific bactericidal activity, low probability of the appearance of stable forms, the absence of ionizing radiation and highly toxic substances. In addition, LTP stimulates healing of infected wounds at the early stages of exposure, which makes LTP a promising method of treating various pathological conditions. Clinical case description.Low-temperature argon plasma treatment was performed for a patient with a diagnosis of: cancer of the right breast cancer T2N1M0, IIB stage. Condition after non-adjuvant PCT and radical resection of the right breast. Complication: Abscess in the area of the postoperative scar. After the 3rd treatment with plasma flow, the wound was sutured and while continuing treatment with low-temperature argon plasma, the patient began radiation therapy of the right breast and regional lymph flow zones in the mode of classical dose fractionation. During the follow-up period, the patient showed positive dynamics in the area of the postoperative scar, which did not lead to a long period of rehabilitation in the postoperative period and radiation therapy was started in a timely manner. Conclusion.Thus, the use of this technique in clinical practice has proven that the period of rehabilitation in the postoperative period is shortened for continuous comprehensive treatment of severe cancer patients with breast cancer.
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Alsadik, Bashar. "A MODIFIED METHOD FOR IMAGE TRIANGULATION USING INCLINED ANGLES." ISPRS - International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences XLI-B3 (June 9, 2016): 453–58. http://dx.doi.org/10.5194/isprs-archives-xli-b3-453-2016.

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The ongoing technical improvements in photogrammetry, Geomatics, computer vision (CV), and robotics offer new possibilities for many applications requiring efficient acquisition of three-dimensional data. Image orientation is one of these important techniques in many applications like mapping, precise measurements, 3D modeling and navigation. <br><br> Image orientation comprises three main techniques of resection, intersection (triangulation) and relative orientation, which are conventionally solved by collinearity equations or by using projection and fundamental matrices. However, different problems still exist in the state – of –the –art of image orientation because of the nonlinearity and the sensitivity to proper initialization and spatial distribution of the points. In this research, a modified method is presented to solve the triangulation problem using inclined angles derived from the measured image coordinates and based on spherical trigonometry rules and vector geometry. The developed procedure shows promising results compared to collinearity approach and to converge to the global minimum even when starting from far approximations. This is based on the strong geometric constraint offered by the inclined angles that are enclosed between the object points and the camera stations. <br><br> Numerical evaluations with perspective and panoramic images are presented and compared with the conventional solution of collinearity equations. The results show the efficiency of the developed model and the convergence of the solution to global minimum even with improper starting values.
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Alsadik, Bashar. "A MODIFIED METHOD FOR IMAGE TRIANGULATION USING INCLINED ANGLES." ISPRS - International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences XLI-B3 (June 9, 2016): 453–58. http://dx.doi.org/10.5194/isprsarchives-xli-b3-453-2016.

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The ongoing technical improvements in photogrammetry, Geomatics, computer vision (CV), and robotics offer new possibilities for many applications requiring efficient acquisition of three-dimensional data. Image orientation is one of these important techniques in many applications like mapping, precise measurements, 3D modeling and navigation. &lt;br&gt;&lt;br&gt; Image orientation comprises three main techniques of resection, intersection (triangulation) and relative orientation, which are conventionally solved by collinearity equations or by using projection and fundamental matrices. However, different problems still exist in the state – of –the –art of image orientation because of the nonlinearity and the sensitivity to proper initialization and spatial distribution of the points. In this research, a modified method is presented to solve the triangulation problem using inclined angles derived from the measured image coordinates and based on spherical trigonometry rules and vector geometry. The developed procedure shows promising results compared to collinearity approach and to converge to the global minimum even when starting from far approximations. This is based on the strong geometric constraint offered by the inclined angles that are enclosed between the object points and the camera stations. &lt;br&gt;&lt;br&gt; Numerical evaluations with perspective and panoramic images are presented and compared with the conventional solution of collinearity equations. The results show the efficiency of the developed model and the convergence of the solution to global minimum even with improper starting values.
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Jhan, Jyun-Ping, Jiann-Yeou Rau, and Chih-Ming Chou. "Underwater 3D Rigid Object Tracking and 6-DOF Estimation: A Case Study of Giant Steel Pipe Scale Model Underwater Installation." Remote Sensing 12, no. 16 (August 12, 2020): 2600. http://dx.doi.org/10.3390/rs12162600.

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The Zengwen desilting tunnel project installed an Elephant Trunk Steel Pipe (ETSP) at the bottom of the reservoir that is designed to connect the new bypass tunnel and reach downward to the sediment surface. Since ETSP is huge and its underwater installation is an unprecedented construction method, there are several uncertainties in its dynamic motion changes during installation. To assure construction safety, a 1:20 ETSP scale model was built to simulate the underwater installation procedure, and its six-degrees-of-freedom (6-DOF) motion parameters were monitored by offline underwater 3D rigid object tracking and photogrammetry. Three cameras were used to form a multicamera system, and several auxiliary devices—such as waterproof housing, tripods, and a waterproof LED—were adopted to protect the cameras and to obtain clear images in the underwater environment. However, since it is difficult for the divers to position the camera and ensure the camera field of view overlap, each camera can only observe the head, middle, and tail parts of ETSP, respectively, leading to a small overlap area among all images. Therefore, it is not possible to perform a traditional method via multiple images forward intersection, where the camera’s positions and orientations have to be calibrated and fixed in advance. Instead, by tracking the 3D coordinates of ETSP and obtaining the camera orientation information via space resection, we propose a multicamera coordinate transformation and adopted a single-camera relative orientation transformation to calculate the 6-DOF motion parameters. The offline procedure is to first acquire the 3D coordinates of ETSP by taking multiposition images with a precalibrated camera in the air and then use the 3D coordinates as control points to perform the space resection of the calibrated underwater cameras. Finally, we calculated the 6-DOF of ETSP by using the camera orientation information through both multi- and single-camera approaches. In this study, we show the results of camera calibration in the air and underwater environment, present the 6-DOF motion parameters of ETSP underwater installation and the reconstructed 4D animation, and compare the differences between the multi- and single-camera approaches.
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Bodnar, O. "SURGICAL TREATMENT OF ANOMALIES OF FIXATION OF THE COLON IN CHILDREN." Clinical anatomy and operative surgery 19, no. 4 (November 26, 2020): 32–36. http://dx.doi.org/10.24061/1727-0847.19.4.2020.48.

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Pyrrhic disease is a congenital anomaly that occurs during embryogenesis due to the fixation of the splenic angle of the colon by a short and highly located left transverse-diaphragmatic ligament, creating a sharp bend and forming a "wellbore". In this case the passage of feces on a cross colon becomes difficult, there is also its sagging to a small pelvis. This pathology is characterized by paroxysmal pain (aggravated by exercise and after eating) and prolonged constipation, which progresses over time. Hilaiditis syndrome is a rather rare pathology in which there is an interposition of the hepatic angle of the colon between the liver and the diaphragm. There are permanent and intermittent localizations. The work generalizes the experience of evaluation of clinical manifestations and remote results of treatment of children with chronic colostasis caused by fixation abnormalities of the colon. 58 children were detected to have Payre’s disease, with Cyilaiditi’s syndrome – 3 children. 24 patients with Payre’s disease and 2 Cyilaiditi’s syndrome were operated on. To assess the effectiveness of surgery, children were divided into two groups: I group – comparative and II group - experienced. In I group (n=12 children) – the analysis of surgical treatment was performed traditionally. In II group (n=14 children) – the analysis of surgical treatment was conducted by means of the methods proposed. Traditional surgical treatment of Payre’s disease in children was followed by relapse of chronic constipation in 45,45%, pain in 50%, flatulence in 33,33% and failure of the ileocoecal closing apparatus in 100% of children. Unsatisfactory outcomes of surgical treatment of Cyilaiditi’s syndrome was observed in a child from the comparative group. Relapse of clinical symptoms to a lesser degree than before the surgery was found in 1 child from the experienced group. To treat Payre’s disease the following operation is proposed: intersection of the left diaphragm-colon ligament, resection of transverse colon and colofixation of the left bending of the colon. To treat Cyilaiditi’s syndrome (in case of dolichoascendocolon) the following operation is suggested: hepatopexy, resection of the right bending of the colon with ascending transversal anastomosis “end to end”, fixing of right bending of the colon. Their reasonability is being proved.
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Jahandideh, Sorosh, Ali Azizi, and Nasser Najibi. "NUMERICAL EVALUATION AND APPLICATION-ORIENTED ANALYSIS FOR FORWARD AND INVERSE RATIONAL FUNCTION MODELS OF TERRAIN-INDEPENDENT CASE IN SATELLITE IMAGERY." Geodesy and cartography 40, no. 3 (September 25, 2014): 99–109. http://dx.doi.org/10.3846/20296991.2014.962731.

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Terrain-independent Rational Polynomial Coefficients (RPCs) are considered as most important part of the optical satellite and aerial imagery data processing especially those ones with high resolution since the proposed RPCs by the aerospace companies have some limitations in particular for using directly by the geoscientists in environmental studies and other Earth observation applications. While the inverse RPCs have more advantageous rather than direct ones, in this study, a new approach is presented in order to provide the inverse RPCs from direct ones and also to satisfy satellite imagery products users. In order to do this, first a spatial 3D-cubic is going to be fitted to the study area approximately including necessary altimetry layers numbers. Next, a range of virtual control points are being created in those altimetry layers randomly and then these points are going to be shifted to the image space by means of given direct RPCs. Hence, the inverse RPCs computes from the direct ones by space resection technique. Finally, the ground coordinates for the corresponding points have derived from different space intersection methodologies, direct RPCs and also inverse ones. Moreover, comparative tests have been developed to assess the effects of different altimetry layers numbers and also the number of virtual control points on the quality of derived inverse RPCs. It is demonstrated here that the precision of derived RPCs are increasing as much as the number of altimetry layers and control points increase. The proposed methodology, computations, data processing and results evaluation are discussed in details.
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Martynenko, D. V., V. P. Voloshin, L. A. Sherman, K. V. Shevyrev, S. A. Oshkukov, and E. V. Stepanov. "Assessment of Acetabulum Deformity During Preoperative Planning for Hip Arthroplasty." Traumatology and Orthopedics of Russia 25, no. 3 (October 18, 2019): 153–64. http://dx.doi.org/10.21823/2311-2905-2019-25-3-153-164.

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Purpose of the study — to improve the two-dimensional planning of total hip joint arthroplasty to ensure precise positioning of the acetabular component in the deformed acetabulum. Materials and methods. Features of roentgenological anatomy of acetabulum and its coverage were studied on 1058 hip joint x-rays in the AP view in accordance with the procedure developed by the authors to define acetabular square — the site of standard positioning of a spherical femoral head in the acetabulum or of a hemispherical acetabular component. The method consisted of identifying the apex of “teardrop” figure; the most lateral points of the pelvic terminal line and roof of the acetabulum; superior part of the acetabular cavity; medial and inferior points of acetabular coverage, and building the sides of acetabular square — medial, inferior, lateral and superior boundary lines. Connection of “teardrop” apex and lateral point of the pelvic terminal line formed the medial side of acetabular square, and a perpendicular to that line drawn through the “teardrop” apex to its inferior side. The lateral side was drawn either through the intersection of the ascending diagonal line — bisector from the top of the “teardrop” figure with the contour of the acetabulum roof, or was a part of the projection of the most lateral point of the acetabular roof on the inferior side of the square. The superior side was a perpendicular connecting the intersection of the ascending diagonal and lateral bounding lines with the medial side of the acetabular square. The area of the deformed acetabular cavity located outside of the acetabular square was assessed as the acetabular defect. Results. Method of defining the acetabular square allowed to identify types of ratios between acetabular cavity and acetabular coverage in transverse (9 types) and longitudinal (7 types) direction. Combination of transverse ratio of acetabular cavity and coverage with longitudinal type allowed to define the options of acetabular deformities in two-dimensional view. The authors identified 25 types of acetabular deformities. Bone defects of acetabular walls were of the major importance among all anatomical features. Cranial defect of acetabulum was observed in 450 cases, medial wall defect — in 38 cases, defect including cranial and medial areas — in 7 cases. Conclusion. The method suggested by the authors to determine acetabular square and acetabular deformity variations allows to screen the anatomical features of the acetabulum during two-dimensional preoperative planning and to make an informed decision on the need to use other planning techniques. The type of acetabular deformity identified during preoperative planning allows to elaborate the indications for replacement of acetabular bone defects and/or resection of acetabular osteophytes.
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Wang, Qiaoli, and Jinfu Zhu. "Deep Learning-Based CT Imaging in Perioperative Period and Nursing of Esophageal Carcinoma Patients." Scientific Programming 2021 (July 28, 2021): 1–8. http://dx.doi.org/10.1155/2021/4453317.

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The study focused on the performance of Convolutional Neural Network- (CNN-) based lymph node recognition model as well as the effects of different rehabilitation nursing methods on patients with esophageal cancer. Specifically, the activation function and loss function were optimized by CNN, to establish a U-Net lymph node recognition model. It was compared with Mean Shift and Fuzzy C-means (FCM) algorithm for the loss value, the mean pixel accuracy (mPA), and intersection over union (IOU). 158 patients with esophageal cancer undergoing radical resection were selected as research subjects. With pathological diagnosis results as the gold standard, the role of CT imaging was evaluated in the diagnosis of esophageal cancer lymph nodes. All subjects were divided into control group (routine nursing) and intervention group (routine nursing + rehabilitation nursing) according to different nursing methods, with 79 cases in each. The two groups were compared in terms of the time in bed, hospital stay, indwelling chest tube time, and VAS scores. It was found that the loss value of the U-Net model was close to 0 when it was stable, and its IOU value and mPA value were significantly higher than those of the Mean Shift and FCM algorithms. The accuracy, sensitivity, specificity, positive predictive value, and negative predictive value of the U-Net model were 84.37%, 80.74%, 88.65%, 85.02%, and 87.16%, respectively. When it came to lymph node metastasis number of 1-2, there were notable differences between CT results and postoperative pathology results, and the difference was statistically significant ( P < 0.05 ). As for their identifying lymph node metastasis area, there was no statistically significant difference ( P > 0.05 ). The intervention group exhibited lower postoperative VAS score, shorter time in bed, and shorter hospital stay and indwelling chest tube time versus the control group ( P < 0.01 ). It suggested that the U-Net model optimized by CNN has high diagnostic efficiency for lymph nodes, and the rehabilitation nursing intervention significantly mitigates postoperative pain and accelerates postoperative recovery.
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Pantalone, Desiree, Gian Carlo Muscas, Tobias Tings, Roberto Paolucci, Maria Nincheri-Kunz, Alessandro Borri, Francesco Taruffi, Luigi Maria Pernice, Pietro Liguori, and Francesco Andreoli. "Peripheral Paraneoplastic Neuropathy, an Uncommon Clinical Onset of Sigmoid Cancer. Case Report and Review of the Literature." Tumori Journal 88, no. 4 (July 2002): 347–49. http://dx.doi.org/10.1177/030089160208800420.

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A case of a 76-year-old man presenting with weakness of the lower legs and bilateral steppage gait is described. Neurological examination revealed a sensorimotor neuropathy with axonopathy and myelinic aspects. At the time of the diagnostic workup an episode of rectal bleeding occurred. Colonoscopy demonstrated an exophytic cancer of the sigmoid colon at 40 cm from the anal verge. At surgery the tumor adhered to the ileum, so a left hemicolectomy and ileo-ileal resection were performed. Tumor stage was Dukes' B, Jass III, Astler-Coller B2, T3N0M0. The patient underwent postoperative chemotherapy and was followed for the past three years. At present he is free of disease and the neuropathy has completely regressed without any dedicated therapy. As reported in the literature the appearance of a paraneoplastic neurological syndrome (PNS) may be the first sign of a malignancy that is occult at the time of clinical presentation. The most widely supported theory about its etiology is that of an autoimmune origin. The paraneoplastic neurological syndrome is considered to be at a point of intersection between tumor immunology, autoimmune neurological disease, and basic neurobiology. Previous experience has resulted in a pathogenic model and in a definition of a group of autoantibodies related to the disease. Small cell lung cancer (SCLC) is the neoplasm most frequently associated with PNS; other malignancies include lymphomas and various hematological malignancies. Some authors reported also that the percentage of patients with a high titer of neuronal autoantibodies is small and several of the autoantibodies are present at low levels without any accompanying clinical manifestation. In a clinical retrospective study of the Mayo Clinic Group 115,081 patients were examined over the period 1984-1993 and only 58 patients (0.05%) could be defined as being affected by a paraneoplastic neurological syndrome. Only five of these patients had colon tumors. The number of patients is so small and so widely scattered among publications that no statistical analysis is possible. Probably the only possibility for early identification of such a syndrome is a high degree of suspicion. In fact, these patients are usually first admitted and studied in a neurological unit, and the diagnosis of a tumor-associated disease is a delayed event.
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Khmyzov, S. O., G. V. Kykosh, and M. Yu Karpinsky. "Role of plantar aponeurosis in the formation of cavus component in recurrent congenital equinocavovarus deformity." TRAUMA 21, no. 6 (April 5, 2021): 33–40. http://dx.doi.org/10.22141/1608-1706.6.21.2020.223886.

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Background. Congenital equinocavovarus deformity (CECVD) is the second most frequent among all congenital disorders of the musculoskeletal system in children, and one of the most common causes of childhood disability in Ukraine. The incidence of CECVD reaches 1–3 cases per 1,000 newborns (35–40 % of all foot deformities). According to some authors, plantar fasciotomy can improve the shape and function of support and walking in these patients. The purpose was to determine the role of plantar aponeurosis in the formation of the cavus component in cases of recurrent CECVD in children. Material and methods. Mathematical researches were carried out using the graph-analytical method. Results. To reduce the arch height when correcting pes cavus, it is necessary to increase significantly the length of the aponeurosis (up to 25 % of its initial length). To perform this task, a significant tensile force must be applied to the aponeurosis, the value of which depends on the magnitude of a decrease in the arch height. So, to reduce the arch height by 10 mm, it is necessary to lengthen the aponeurosis by 12 mm, for which a constant force of 932 N must be applied to it. To reduce the arch height by 20 mm, the magnitude of the tensile force applied to the aponeurosis must be increased to 1,438 N, which is almost impossible. Therefore, the presence of a shortened aponeurosis is a significant obstacle for the effective correction of pes cavus. Conclusions. Correction of pes cavus requires a significant decrease in the height of its longitudinal arch, which leads to a significant lengthening of the aponeurosis, up to 25 % of its initial length. To ensure an increase in the length of the aponeurosis, the presence of a significant constant tensile force that exceeds 1000 N is necessary. Plantar aponeurosis plays a direct role in supporting the longitudinal arch of the foot, and is one of the causes for the persistence of pes cavus in patients with recurrent CECVD, which does not respond to conservative treatment. To correct cavus foot, in the failure of conservative treatment, it is necessary to lengthen it by surgical intervention (intersection). The value of the angle of the longitudinal arch of the foot of 110° can be chosen as a criterion for choosing a decision in favor of preserving or resection of the aponeurosis.
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Coward, Victoria, Jacky Chen, Nalan Gokgoz, Kim Tsoi, Jay S. Wunder, and Irene L. Andrulis. "Abstract 5609: Investigating the undifferentiated pleomorphic sarcoma microenvironment through cytokine profiles of primary tumor and immune infiltrates." Cancer Research 82, no. 12_Supplement (June 15, 2022): 5609. http://dx.doi.org/10.1158/1538-7445.am2022-5609.

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Abstract Sarcoma is a heterogeneous group of connective tissue cancers with over 60 subtypes. Curative treatment relies on surgical resection combined with radiation. In the event of metastasis, chemotherapy is used but generally only with palliative intent. Given the heterogeneity of sarcomas, targeted therapies are limited, which has contributed to the relatively stagnant survival rates seen in the past decades. Objective: Personalized treatments, such as adoptive cell therapy (ACT), may be promising for select sarcoma patients, specifically those with Undifferentiated Pleomorphic Sarcoma (UPS). To better understand ACT’s feasibility for UPS, we aim to investigate the intersection of tumor-infiltrating lymphocytes (TILs) and tumor cells by examining their cytokine output, whose role remains largely unstudied. Methods: Tissue samples from untreated sarcoma patients have been collected and viably preserved by our group. The samples were processed for in vitro expansion of tumor or TIL cell lines. Tumor cultures were validated with Whole Exome Sequencing (WES) to ensure tumor-specific variations were retained. TILs were isolated with tumor fragment (TF) processing and magnetic bead coated anti-CD3/CD28 Rapid Expansion Protocol (REP). After validating tumor cultures, both tumor and TIL-secreted cytokines were evaluated using Luminex assays. Results: Of the 11 primary UPS samples cultured, 10 generated viable cell cultures as defined by the presentation of stable growth beyond passage 5. A total of 3 cell lines were selected for further validation, and through WES, retained tumor specific variations beyond passage 5. On the other hand, the sarcoma-optimized TF and REP protocols expanded TILs from 7 of 8 UPS cases and yielded up to 6 x 10^7 cells. Although IL-2 is commonly used to facilitate TIL growth, it can also cause activation-induced cell death which is problematic for therapy. We demonstrated that an alternative γ-chain interleukin, IL-15, can support UPS TIL growth comparable to IL-2. Unbiased cytokine screening detected anti-tumoral CXCL9/IFN-γ and pro-tumoral IL-10/TGF-Beta as highly secreted by TIL cultures while some tumor cultures secreted relatively high concentrations of IL-6 and CCL2. Conclusion: We developed a robust in vitro pipeline to expand sarcoma tumor cultures and TILs for downstream characterization. Functional assays aimed at dissecting the consequences of tumor-mediated IL-6 secretion are underway. These include siRNA-induced knock downs of genes hypothesized to augment the cytokine profile of tumor cells. Future evaluation of TILs will identify their clinical efficacy via flow cytometry and intracellular cytokine staining. Understanding cytokine secretion from both the tumor and immune components of sarcoma will aid in elucidating interactions within the microenvironment that may be therapeutically relevant. Citation Format: Victoria Coward, Jacky Chen, Nalan Gokgoz, Kim Tsoi, Jay S. Wunder, Irene L. Andrulis. Investigating the undifferentiated pleomorphic sarcoma microenvironment through cytokine profiles of primary tumor and immune infiltrates [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2022; 2022 Apr 8-13. Philadelphia (PA): AACR; Cancer Res 2022;82(12_Suppl):Abstract nr 5609.
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Sadeghi, F., and H. Arefi. "OCCLUDED AREA REMOVING FROM HANDHELD LASER SCANNER DATA DURING 3D BUILDING MODELLING." ISPRS - International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences XLII-4/W18 (October 19, 2019): 935–39. http://dx.doi.org/10.5194/isprs-archives-xlii-4-w18-935-2019.

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Abstract. 3D building modelling has been turned to be one of the most interesting and hottest subjects in photogrammetry in last two decades, and it seems that photogrammetry provides the only economic means to acquire truly 3D city-data. Most of the researches proposed methods for 3d building modelling in LoD2 using aerial images and LIDAR data and the produced models will be enriched by oblique images, therefore there is always a demand for a user to interpret the façade or in other manual building reconstruction process the operator should draw boundaries to represent the building model and the process will be too time-consuming for 3d modelling for a whole city. Creating building facade models for a whole city requires considerable work, therefore for decades, much research has been dedicated to the automation of this reconstruction process. Nowadays researchers attempt to recommend a new method which is flexible to model hug variety of buildings and has a solution for several challenges such as irrelevant objects (pedestrians, trees, traffic signs, etc.), occluded areas and non-homogenous data. Based on various 3d building models applications, namely navigation systems, location-based system, city planning and etc. the demand for adding semantic features (such as windows and doors) is increasing and becoming more essential, therefore simple blocks as the representation of 3d buildings aren’t sufficient anymore. Therefore 2.5 models which show the façade details using pixel values have been substituted by LoD3 models recently.The lack of automation in image based approaches can be explained by the difficulties in image interpretation. Specifically, factors like illumination and occlusion can cause considerable confusion for machine understanding and some conditions (relative orientation, feature matching, etc.) need to be accurately determined to transfer image pixels to 3D coordinates. In recent years, terrestrial laser scanning data has been proven as a valuable source for building facade reconstruction. The point density of stationary laser scanning in urban areas can be up to hundreds or thousands of points per square meter, which is high enough for documenting most details on building facades. In comparison with image-based modelling, several steps such as image matching, intersection and resection will be eliminated, while there is no need to image interpret in laser data-based reconstruction approaches, these methods face major challenges such as extracting meaningful structures from a huge amount of data.This paper presents a data-driven algorithm for façade reconstruction, using a handheld laser scanner, Zebedee. The mentioned device is consisting of 2d laser scanner and an inertial measurement unit mounted on one or two springs, it has 270-degree field of view. Its mass is 210 g which makes it ideal for low measurement and it is maximum range is 30 m. The proposed method was implemented by using the Zebedee point cloud in order to determine the challenges of zeb1 data and ensure that the introduced device can be practical for 3d reconstruction.Due to obstacle existence, operator gross errors while data capturing and façade elements arrangement, there will always be occluded area and shadows in produced data. Occluded area cause tribulation in machine understanding and problems for automatic reconstruction algorithms. The proposed method represents a new way to detect occluded area and remove the artificial objects which are produced by them. The 3d point cloud is used to cover all façade elements and details, also image matching and producing 3-dimensional data steps will be omitted from the process.The proposed workflow is indicated in figure 1. Most researches such as road, building or other objects detection and reconstruction put ground points detection in priority in order to decrease data volume and processing time, so as a pre-processing step, point cloud is classified into two separate groups (non-ground and ground points).
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Nikitin, I. G., A. E. Nikitin, A. A. Karabinenko, V. A. Gorskiy, L. Yu Ilchenko, R. H. Asimov, P. S. Glushkov, K. A. Shemyatovskiy, and O. A. Roginko. "Short bowel syndrome against the background of adhesive disease of the abdominal cavity." Experimental and Clinical Gastroenterology 174, no. 5 (June 29, 2020): 113–19. http://dx.doi.org/10.31146/1682-8658-ecg-177-5-113-119.

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Short bowel syndrome is a pathological symptom complex that occurs after removal (resection) of the small intestine (more than 25% of its length), or when there is a signifi cant violation of its function. The most common cause of short bowel syndrome is adhesions of the small intestine that occur after surgical interventions on the abdominal organs. A description of the clinical observation of short bowel syndrome with severe manifestations of enteric insufficiency in a 41-year old patient is given. The patient was admitted to the surgical Department of FGBUZ Central clinical of the hospital Russian Academy of Sciences with com-plaints of General weakness, pain, spastic nature in the abdomen without clear localization, pain in the area of operational wound (for 4 months had 4 surgery for adhesive intestinal obstruction), abdominal distention, thirst, dry mouth, semiliquid chair 3–4 times a day, weight loss for the last 7 months before the hospitalization at 22 kg, the body mass index was 17.3 kg/m2. After the last surgical intervention, ileostomy of the ascending colon was applied using the Brooke method in connection with adhesive small bowel obstruction. The functioning segment of the jejunum was anastomosed with the ascending colon and was 22 cm long. At admission, the state of moderate severity, moderately emaciated, dehydrated. Liquid stool up to 6 times a day, without pathological impurities. MSCT of abdominal organs from 03.05.2018 with contrast: in meso — and hypogastria (mainly on the left), expanded loops of the small intestine (up to a maximum of 37–38 mm) fi lled with liquid content were visualized, the contrast preparation in the above described loops of the small intestine was not visualized. Additionally, non-expanded loops of the small intestine were visualized in the hypogastria and did not contain contrast. Non-functional loops of the small intestine in the meso — and hypogastrium. Liver, biliary system, pancreas, spleen — without features. On the background of complex therapy, the stabilization of clinical and laboratory indicators was achieved, which allowed to plan surgical treatment-laparotomy, closure of ileostomy, imposition of small intestine anastomosis in the large intestine. A laparotomy was performed with the right pararectal access. Continuous viscero-visceral and of viscero-peritoneal splices were found in the abdominal cavity. With technical difficulties caused by fi brous-calcifi ed splices, it was possible to separate the ascending colon and the part of the jejunum that goes to the anterior abdominal wall to the site of the bred jejunostomy. The intersection of the jejunum stoma was performed in close contact with the anterior abdominal wall. A double-row “end-to-side” anastomosis was formed with the middle third of the ascending colon. When performing laparotomy with left pararectal access under conditions of a pronounced adhesive process, it was possible to isolate a section of the sigmoid colon and a loop of the small intestine that was previously disabled (during the previous operation). Ileosigmoidostomy formed a double row “side to side”. The preserved portion of the small intestine was 85 cm. In the postoperative period, there were signs of endogenous intoxication. Against the background of intestinal paresis and severe intoxication, there was an increase in the markers of infl amemation and pancytopenia. Complex therapy with parenteral mixtures, prebiotics and antimicrobial drugs stopped the symptoms of intoxication, the activity of infl ammation, and improved laboratory parameters, which allowed us to gradually switch to oral food intake. Semi-formed stool 1–2 times a day. She was discharged on the 10th day after the operation for outpatient treatment under the supervision of a surgeon and gastroenterologist. One-year rehabilitation period with a positive effect, which indicates the uniqueness of this clinical observation.
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Güngör, Harun Reşit, Nusret Ök, Kadir Ağladıoğlu, Semih Akkaya, and Esat Kıter. "Correlation Between Asymmetric Resection of Posterior Femoral Condyles and Femoral Component Rotation in Total Knee Arthroplasty." Orthopaedic Journal of Sports Medicine 2, no. 11_suppl3 (November 1, 2014): 2325967114S0014. http://dx.doi.org/10.1177/2325967114s00140.

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Objectives: Pertaining to peculiar designs of current knee prostheses, more bone is removed from posteromedial femoral condyle than posterolateral condyle to obtain desired femoral component rotation. The aim of our study was to evaluate whether there is a correlation between the asymmetry of the cuts and the femoral component rotation in total knee arthroplasty. Methods: We built a model to simulate anterior chamfer cut (ACC) performed during total knee arthroplasty for measuring posterior condylar offset (PCO). Right knee axial MRI slices of a total 290 consecutive patients (142 male, 138 female, and mean age 31.39 ± 6.6) were examined. A parallel line to surgical transepiphyseal axis was drawn, and placed at the deepest part of trochlear groove. Posteromedial and posterolateral condylar offsets were measured by drawing perpendicular lines to ACC beginning from the intersection points of both anteromedial and anterolateral cortices to posterior joint line (PJL), respectively. Differences between posteromedial and posterolateral PCO were calculated, and femoral rotation angles (FRA) relative to PJL were measured. Results: The mean surgical FRA was 4.76 ± 1.16 degrees and the mean PCO differencesss- was 4.35 ± 1.04 mm for the whole group and there was no statistically significant difference between genders. There was a strong correlation between surgical FRA and PCO difference (p<0.0001, r=0.803). Linear regression analyses revealed that 0.8 mm of difference between the anteroposterior dimensions of medial and lateral PCO corresponds to 1 degree of surgical FRA (p<0.0001, R2=0.645). Conclusion: Correlation between the asymmetry of posterior chamfer cuts and achieved femoral component rotation can verify the accuracy of desired rotation, intraoperatively. However, further clinical investigations should be planned to test the results of our morphometric study.
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Giovanni, Capovilla, Sefora Pierobon Elisa, Moletta Lucia, Provenzano Luca, Costantini Mario, Salvador Renato, Merigliano Stefano, and Valmasoni Michele. "P146 AN IMPROVEMENT TO THE CIRCULAR STAPLING ANASTOMOSIS TECHNIQUE DURING MINIMALLY." Diseases of the Esophagus 32, Supplement_2 (November 2019). http://dx.doi.org/10.1093/dote/doz092.146.

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Abstract Aim The circular stapled (CS) technique with transoral placement of the anvil is commonly used to perform the esophago-gastric anastomosis during minimally invasive esophagectomy (MIE). The procedure is safe, efficient and highly reproducible, however the intersection between the circular plane of the stapler and the linear staple line of the esophageal stump can expose the anastomosis to the formation of dog ears and therefore increase the risk of anastomotic leakage (AL). We describe a simple modification of the CS technique that avoid the formation of staple lines intersection. Background and Methods We prospectively collected data on a small group of patients who underwent MIE for cancer using our modified CS technique. Our technical modification consists in folding the linear esophageal transection line with a stitch around the anvil shaft, in order to include the staple line in the resection during the EEATM firing (figure 1). Feasibility has been evaluated as the percentage of cases in which the improved anastomosis technique has been carried out successfully with the formation of a complete anastomotic ring. Safety has been defined as the absence of procedure related complications. Results MIE was performed in ten patients using our modified CS technique, median age was 55 years. All the procedures were successfully completed with complete resection of the linear esophageal staple line and no intraoperative complication. Only one patient developed a postoperative AL, that was only detected by barium swallow and did not cause any symptom or clinical sign. Conclusions Our modified CS technique is simple, feasible and safe. Further studies are needed to evaluate its efficacy in preventing the occurrence of anastomosis leakage.
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Kimura, Masahiro, Yoshiyuki Kuwabara, Akira Mitsui, Takaya Nagasaki, and Seiichi Nakaya. "A New Approach to the Laparoscopic Double Stapling Technique: Exploration and Reinforcement of Weak Points." Journal of Advances in Medicine and Medical Research, March 15, 2021, 1–7. http://dx.doi.org/10.9734/jammr/2021/v33i530840.

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Background: Anastomotic leakage is a serious complication in colorectal surgery, often associated with higher morbidity and mortality. Even with advances in medical technology and devices, the rates of anastomotic leakage is not on downward trend. We describe our experimental and clinical validation of our method to overcome the weakness of the double stapling technique, especially the intersecting staple lines. Methods: Experimentally, we conducted double stapled anastomosis with pig small intestines. In order to verify pressure resistance, the anastomosis was tested and compared with that formed by a conventional stapler and a reinforced cartridge preattached to a Neoveil sheet. Additionally, during the anastomosis performed by the circular stapler, both ends of the Neoveil sheet were grasped by forceps, and the Neoveil sheet was pulled tight to fit the anastomotic surface. The burst pressure of the anastomosis was recorded. Clinically, we used a reinforced cartridge for rectal surgery performing a low anterior resection and verified its efficacy and safety. Results: Unlike a conventional stapler, our methods with the use of a reinforced cartridge showed no leakage from the intersecting staple lines. Clinically, our method has been used for 20 patients without complications, including leakage and bleeding. Conclusion: The addition of reinforcing material to the linear stapler should lead to increased strength of the anastomosis. We believe that a double stapling anastomosis that uses our method for the intersection lines provides increased safety and security and thereby should lead to a reduced rate of suture failure after rectal resection.
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Mamdani, Hirva, Sandro Matosevic, Ahmed Bilal Khalid, Gregory Durm, and Shadia I. Jalal. "Immunotherapy in Lung Cancer: Current Landscape and Future Directions." Frontiers in Immunology 13 (February 9, 2022). http://dx.doi.org/10.3389/fimmu.2022.823618.

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Over the past decade, lung cancer treatment has undergone a major paradigm shift. A greater understanding of lung cancer biology has led to the development of many effective targeted therapies as well as of immunotherapy. Immune checkpoint inhibitors (ICIs) have shown tremendous benefit in the treatment of non-small cell lung cancer (NSCLC) and are now being used as first-line therapies in metastatic disease, consolidation therapy following chemoradiation in unresectable locally advanced disease, and adjuvant therapy following surgical resection and chemotherapy in resectable disease. Despite these benefits, predicting who will respond to ICIs has proven to be difficult and there remains a need to discover new predictive immunotherapy biomarkers. Furthermore, resistance to ICIs in lung cancer is frequent either because of a lack of response or disease progression after an initial response. The utility of ICIs in the treatment of small cell lung cancer (SCLC) remains limited to first-line treatment of extensive stage disease in combination with chemotherapy with modest impact on overall survival. It is thus important to explore and exploit additional targets to reap the full benefits of immunotherapy in the treatment of lung cancer. Here, we will summarize the current state of immunotherapy in lung cancer, discuss novel targets, and explore the intersection between DNA repair defects and immunotherapy.
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Kitaguchi, Daichi, Toru Fujino, Nobuyoshi Takeshita, Hiro Hasegawa, Kensaku Mori, and Masaaki Ito. "Limited generalizability of single deep neural network for surgical instrument segmentation in different surgical environments." Scientific Reports 12, no. 1 (July 22, 2022). http://dx.doi.org/10.1038/s41598-022-16923-8.

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AbstractClarifying the generalizability of deep-learning-based surgical-instrument segmentation networks in diverse surgical environments is important in recognizing the challenges of overfitting in surgical-device development. This study comprehensively evaluated deep neural network generalizability for surgical instrument segmentation using 5238 images randomly extracted from 128 intraoperative videos. The video dataset contained 112 laparoscopic colorectal resection, 5 laparoscopic distal gastrectomy, 5 laparoscopic cholecystectomy, and 6 laparoscopic partial hepatectomy cases. Deep-learning-based surgical-instrument segmentation was performed for test sets with (1) the same conditions as the training set; (2) the same recognition target surgical instrument and surgery type but different laparoscopic recording systems; (3) the same laparoscopic recording system and surgery type but slightly different recognition target laparoscopic surgical forceps; (4) the same laparoscopic recording system and recognition target surgical instrument but different surgery types. The mean average precision and mean intersection over union for test sets 1, 2, 3, and 4 were 0.941 and 0.887, 0.866 and 0.671, 0.772 and 0.676, and 0.588 and 0.395, respectively. Therefore, the recognition accuracy decreased even under slightly different conditions. The results of this study reveal the limited generalizability of deep neural networks in the field of surgical artificial intelligence and caution against deep-learning-based biased datasets and models.Trial Registration Number: 2020-315, date of registration: October 5, 2020.
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45

Anania, Pasquale, Rosa Mirapeix-Lucas, Gianluigi Zona, Alessandro Prior, Carlos Asencio Cortes, and Fernando Muñoz Hernandez. "Middle Cranial Fossa Approach: Anatomical Study on Skull Base Triangles as a Landmark for a Safe Anterior Petrosectomy." Journal of Neurological Surgery Part B: Skull Base, September 12, 2019. http://dx.doi.org/10.1055/s-0039-1696957.

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Abstract Objective The Kawase approach provides access to the petroclival and posterior cavernous sinus regions, cerebellopontine angle, and upper basilar artery territory. Nevertheless, it remains one of the most challenging approach for neurosurgeons, due to the considerable related morbidity and mortality. The goal of this study was to evaluate the relationship between anatomical landmarks and their possible variations, and to measure the extension of the Kawase space, to define the reliability of these landmarks while performing an anterior petrosectomy. Design Using eight cadaveric specimens (15 sides), an anatomical dissections and extradural exposure of the Kawase area were performed. Settings A two-step analysis of the distances between the mandibular branch of the trigeminal nerve (V3) and the structures at risk of iatrogenic damage was performed. Main outcome measures We measured the distance between V3 and the basal turn of the cochlea, and between V3 and the internal acoustic canal (IAC), analyzing the limits of bone resection without causing hearing damage. Results We analyzed eight cadaveric (15 sides) formalin-fixed heads injected with colored silicone: four males and four females of Caucasian race (mean age: 73.83 years). We found a mean distance of 10.46 ± 1.13 mm between the great superficial petrous nerve (GSPN) intersection with V3 and the basal turn of the cochlea, and of 11.92 ± 1.71 mm between the origin point of V3 from the Gasserian ganglion and the fundus of the IAC. Conclusion The knowledge of the safe distance between the most applicable anatomic landmarks and the hearing structures is a practical and useful method to perform this approach reducing related comorbidity.
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Liu, Leheng, Zhixia Dong, Jinnian Cheng, Xiongzhu Bu, Kaili Qiu, Chuan Yang, Jing Wang, et al. "Diagnosis and segmentation effect of the ME-NBI-based deep learning model on gastric neoplasms in patients with suspected superficial lesions - a multicenter study." Frontiers in Oncology 12 (January 16, 2023). http://dx.doi.org/10.3389/fonc.2022.1075578.

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BackgroundEndoscopically visible gastric neoplastic lesions (GNLs), including early gastric cancer and intraepithelial neoplasia, should be accurately diagnosed and promptly treated. However, a high rate of missed diagnosis of GNLs contributes to the potential risk of the progression of gastric cancer. The aim of this study was to develop a deep learning-based computer-aided diagnosis (CAD) system for the diagnosis and segmentation of GNLs under magnifying endoscopy with narrow-band imaging (ME-NBI) in patients with suspected superficial lesions.MethodsME-NBI images of patients with GNLs in two centers were retrospectively analysed. Two convolutional neural network (CNN) modules were developed and trained on these images. CNN1 was trained to diagnose GNLs, and CNN2 was trained for segmentation. An additional internal test set and an external test set from another center were used to evaluate the diagnosis and segmentation performance.ResultsCNN1 showed a diagnostic performance with an accuracy, sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of 90.8%, 92.5%, 89.0%, 89.4% and 92.2%, respectively, and an area under the curve (AUC) of 0.928 in the internal test set. With CNN1 assistance, all endoscopists had a higher accuracy than for an independent diagnosis. The average intersection over union (IOU) between CNN2 and the ground truth was 0.5837, with a precision, recall and the Dice coefficient of 0.776, 0.983 and 0.867, respectively.ConclusionsThis CAD system can be used as an auxiliary tool to diagnose and segment GNLs, assisting endoscopists in more accurately diagnosing GNLs and delineating their extent to improve the positive rate of lesion biopsy and ensure the integrity of endoscopic resection.
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Azam, Muhammad Adeel, Claudio Sampieri, Alessandro Ioppi, Pietro Benzi, Giorgio Gregory Giordano, Marta De Vecchi, Valentina Campagnari, et al. "Videomics of the Upper Aero-Digestive Tract Cancer: Deep Learning Applied to White Light and Narrow Band Imaging for Automatic Segmentation of Endoscopic Images." Frontiers in Oncology 12 (June 1, 2022). http://dx.doi.org/10.3389/fonc.2022.900451.

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IntroductionNarrow Band Imaging (NBI) is an endoscopic visualization technique useful for upper aero-digestive tract (UADT) cancer detection and margins evaluation. However, NBI analysis is strongly operator-dependent and requires high expertise, thus limiting its wider implementation. Recently, artificial intelligence (AI) has demonstrated potential for applications in UADT videoendoscopy. Among AI methods, deep learning algorithms, and especially convolutional neural networks (CNNs), are particularly suitable for delineating cancers on videoendoscopy. This study is aimed to develop a CNN for automatic semantic segmentation of UADT cancer on endoscopic images.Materials and MethodsA dataset of white light and NBI videoframes of laryngeal squamous cell carcinoma (LSCC) was collected and manually annotated. A novel DL segmentation model (SegMENT) was designed. SegMENT relies on DeepLabV3+ CNN architecture, modified using Xception as a backbone and incorporating ensemble features from other CNNs. The performance of SegMENT was compared to state-of-the-art CNNs (UNet, ResUNet, and DeepLabv3). SegMENT was then validated on two external datasets of NBI images of oropharyngeal (OPSCC) and oral cavity SCC (OSCC) obtained from a previously published study. The impact of in-domain transfer learning through an ensemble technique was evaluated on the external datasets.Results219 LSCC patients were retrospectively included in the study. A total of 683 videoframes composed the LSCC dataset, while the external validation cohorts of OPSCC and OCSCC contained 116 and 102 images. On the LSCC dataset, SegMENT outperformed the other DL models, obtaining the following median values: 0.68 intersection over union (IoU), 0.81 dice similarity coefficient (DSC), 0.95 recall, 0.78 precision, 0.97 accuracy. For the OCSCC and OPSCC datasets, results were superior compared to previously published data: the median performance metrics were, respectively, improved as follows: DSC=10.3% and 11.9%, recall=15.0% and 5.1%, precision=17.0% and 14.7%, accuracy=4.1% and 10.3%.ConclusionSegMENT achieved promising performances, showing that automatic tumor segmentation in endoscopic images is feasible even within the highly heterogeneous and complex UADT environment. SegMENT outperformed the previously published results on the external validation cohorts. The model demonstrated potential for improved detection of early tumors, more precise biopsies, and better selection of resection margins.
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