Journal articles on the topic 'Repository and Related Studies'
To see the other types of publications on this topic, follow the link: Repository and Related Studies.
Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles
Consult the top 50 journal articles for your research on the topic 'Repository and Related Studies.'
Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.
You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.
Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.
1
Gkoumas, Aristeidis. "Challenges and obstacles for the first digital repository for tourism studies in Greece." European Journal of Tourism Research 18 (March 1, 2018): 146–59. http://dx.doi.org/10.54055/ejtr.v18i.318.
Full textAbstract:
This paper evaluates the visibility, utility, and operability of the first Digital Repository for Tourism Studies in Greece. The creation of the repository was a project that funded and supervised by the Ministry of Tourism, aiming at the collection and analysis of tourism research, conducted from 1980 and onwards. By following a qualitative approach, this study analyzes the challenges and obstacles of developing a digital archive of scientific publications, studies, Ph.D. dissertations and other research data related with tourism in Greece. In particular, it outlines the financial limitations of the project; operational dysfunctions of the online archive; security of the digital content and issues of maintenance, management and technical support of the digital repository in the future. Based on desk review, personal interviews and peer-research working groups, attended by representatives of major tourism institutions, professional organizations and public authorities, the findings of this inquiry indicate that financial and human resources insufficiency, inadequate time frame and lack of promotion, have hindered the success of the project. The paper concludes with specific recommendations for the efficient management and financial sustainability, security of web content and optimal promotion of open access repositories.
2
Bucaciuc Mracica, Teodora, Anca Anghel, Catalin Florentin Ion, Corina Violeta Moraru, Robi Tacutu, and Gligor Andrei Lazar. "MetaboAge DB: a repository of known ageing-related changes in the human metabolome." Biogerontology 21, no. 6 (August 12, 2020): 763–71. http://dx.doi.org/10.1007/s10522-020-09892-w.
Full textAbstract:
Abstract Accumulating metabolomics data is starting to become extremely useful in understanding the ageing process, by providing a snapshot into the metabolic state of tissues and organs, at different ages. Molecular studies of such metabolic variations during “normal” ageing can hence guide lifestyle changes and/or medical interventions aimed at improving healthspan and perhaps even lifespan. In this work, we present MetaboAge, a freely accessible database which hosts ageing-related metabolite changes, occurring in healthy individuals. Data is automatically filtered and then manually curated from scientific articles reporting statistically significant associations of human metabolite variations or correlations with ageing. Up to date, MetaboAge contains 408 metabolites annotated with their biological and chemical information, and more than 1515 ageing-related variations, graphically represented on the website grouped by validation methods, sex and age-groups. The MetaboAge database aims to continually structure the expanding information from the field of metabolomics in relation to ageing, thus making it more accessible for further research in gerontology.
3
Nudelman, Kelly N. H., Kelley Faber, Colleen M. Mitchell, Chris C. Hobbick, Tae-Hwi Schwantes-An, Catharine M. Wyss, Kristi Wilmes, et al. "P3-127: NATIONAL CELL REPOSITORY FOR ALZHEIMER'S DISEASE: A BIOREPOSITORY FOR ALZHEIMER'S DISEASE AND RELATED DEMENTIA STUDIES." Alzheimer's & Dementia 14, no. 7S_Part_21 (July 1, 2006): P1116. http://dx.doi.org/10.1016/j.jalz.2018.06.1484.
Full text
4
Ning, Lin, Tianyu Cui, Boyang Zheng, Nuo Wang, Jiaxin Luo, Beilei Yang, Mengze Du, Jun Cheng, Yiying Dou, and Dong Wang. "MNDR v3.0: mammal ncRNA–disease repository with increased coverage and annotation." Nucleic Acids Research 49, no. D1 (August 24, 2020): D160—D164. http://dx.doi.org/10.1093/nar/gkaa707.
Full textAbstract:
Abstract Many studies have indicated that non-coding RNA (ncRNA) dysfunction is closely related to numerous diseases. Recently, accumulated ncRNA–disease associations have made related databases insufficient to meet the demands of biomedical research. The constant updating of ncRNA–disease resources has become essential. Here, we have updated the mammal ncRNA–disease repository (MNDR, http://www.rna-society.org/mndr/) to version 3.0, containing more than one million entries, four-fold increment in data compared to the previous version. Experimental and predicted circRNA–disease associations have been integrated, increasing the number of categories of ncRNAs to five, and the number of mammalian species to 11. Moreover, ncRNA–disease related drug annotations and associations, as well as ncRNA subcellular localizations and interactions, were added. In addition, three ncRNA–disease (miRNA/lncRNA/circRNA) prediction tools were provided, and the website was also optimized, making it more practical and user-friendly. In summary, MNDR v3.0 will be a valuable resource for the investigation of disease mechanisms and clinical treatment strategies.
5
Pinto, Daniela Maciel, Geraldo Stachetti Rodrigues, Gustavo Spadotti Amaral Castro, Gisele Vilela Freitas, Angelo Mansur Mendes, Lauro Rodrigues Nogueira Júnior, Julio Cesar Bogiani, et al. "GEOINFO: impactos sociais do repositório de dados de pesquisa da EMBRAPA." Páginas a&b : Arquivos & Bibliotecas, esp. (2020): 145–49. http://dx.doi.org/10.21747/21836671/pagnesppk17.
Full textAbstract:
GeoInfo is a repository that provides the spatial research data generated by the Brazilian Agricultural Research Corporation (EMBRAPA) to understand the dynamics of agriculture in Brazilian territory. Considering the efforts required for the implantation and institutionalization of the repository, the absence of Information Science studies related to the investigation of the impact of the uses made from the data and information made available in research data repositories, as well as the impact assessment process used by EMBRAPA since 1989, it is opportune to investigate the impact of the repository for its target audience, that is, geoscience specialists. Thus, the objective of this work is to present the results of an impact assessment carried out with GeoInfo, based on the “Ambitec-TICs: Module of criteria and impact indicators for Information and Communication Technologies”, specifically for the social dimension, existing at Ambitec-TICs
6
Kapoor, N., S. Saxena, and L. Gambhir. "FUNGAL ENDOPHYTES AS REPOSITORY OF XANTHINE OXIDASE INHIBITOR." INDIAN DRUGS 56, no. 03 (March 28, 2019): 7–11. http://dx.doi.org/10.53879/id.56.03.11371.
Full textAbstract:
Xanthine oxidase, a key enzyme of purine metabolism, is considered to be a prime target for the treatment of hyperuricemia and oxidative stress related disorders. Allopurinol and febuxostat are two FDA approved xanthine oxidase inhibitors currently being used for management of chronic hyperuricemia. Plethora of natural sources has been explored in search of novel chemical templates for the development of antihyperuricemic drugs. Studies in past decade have shown the potential of endophytic fungi, which colonize the internal tissues of plants without any evident sign of their ubiquitous existence, as repository of novel chemical entities exhibiting antimicrobial, anti-oxidant, anti-inflammatory and anticancer potential. However, very scanty preliminary data is available of exploration of xanthine oxidase inhibitors from fungal endophytes. The present review summarizes the efficacy of xanthine oxidase as target for developing ant-gout agents and highlights the prospective of endophytic fungi as producers of xanthine oxidase inhibitors for the anti-hyperuricemic therapy regimen.
7
Ribeiro, Tayse Virgulino. "Android Applications based on software repository analysis." Singular Engenharia, Tecnologia e Gestão 1, no. 2 (October 19, 2019): 6–13. http://dx.doi.org/10.33911/singular-etg.v1i2.55.
Full textAbstract:
Context: Software repositories have been a source for studies about software evolution and its relation to software defects. In addition, the context of repositories has also been used for the purpose of analyzing refactoring practiced by programmers throughout the development process. Objective: Our objective is based on android projects stored in software repositories, to determine what types of transformations, that is, which refactorings are used, seeking to relate them to quality and security factors. Method: This research uses as an approach an exploratory study of a qualitative character, based on a systematic review of the literature, which will be carried out between the period from 2015 to 2019, as well as the application of research and quality criteria regarding the work context. In addition, develop a case study with projects for Android, relating refactoring quality criteria to non-aggregated projects in software repositories, glimpsing comparative and resulting factors. Expected results: It is expected with this review analysis and a summary of existing literature on Code Quality in the process of Software Refactoring for Android projects. Conclusions: The research is guided by this approach in identifying the types of refactorings practiced and extracting the related quality factors in the development process. We believe that our results will benefit in the updating and summary of the literature in the context of refactoring, glimpsing comparative factors.
8
Bonales, L. J., J. M. Elorrieta, C. Menor-Salván, and J. Cobos. "The behavior of unirradiated UO2and uraninite under repository conditions characterized by Raman." MRS Advances 1, no. 62 (2016): 4157–62. http://dx.doi.org/10.1557/adv.2017.203.
Full textAbstract:
ABSTRACTRaman spectroscopy studies have been performed on one hand to identify different materials related to spent nuclear fuel (SNF), and on the other hand to study the behavior of SNF at different storage conditions. Specifically, the expected oxidation of the SNF matrix under dry storage conditions and the formation of secondary phases (SP), as a result of corrosion of SNF in a deep geological repository, have been studied. In order to perform these experiments, two protocols based on the Raman spectroscopy technique have been developed. The results show U4O9/U3O7and U3O8as oxidation products of UO2powder at high temperatures in air, and the secondary phase formation (rutherfordine, UO2(CO3), soddyite, (UO2)2SiO4•2H2O, uranophane alpha Ca(UO2)2(SiO3OH)2•5H2O and kasolite, PbUO2SiO4•H2O), due to uraninite corrosion under the conditions of Sierra Albarrana (Spain).
9
Lake, Jeffrey, Leah Rae Donahue, Cathy Lutz, Stephan Rockwood, and Michael Sasner. "The Jackson Laboratory repository: model selection for immunology research (82.10)." Journal of Immunology 178, no. 1_Supplement (April 1, 2007): S111. http://dx.doi.org/10.4049/jimmunol.178.supp.82.10.
Full textAbstract:
Abstract The mouse continues as one of the most important model organisms. The Jackson Laboratory Repository serves as a centralized facility for developing, rederiving, cryopreserving and distributing mouse models. The Repository contains a large repertoire of mouse strains related to immunology research that have applications in studies of basic immunology, innate immunity, cancer research, autoimmunity, allergic diseases, and infectious diseases. Selecting appropriate mutant mice is often difficult. For example, mice devoid of CD4+ T cells are found in 3 different strains including a Cd4 −/− strain (B6.129S2-Cd4tm1Mak/J), a strain where MHC class II genes were deleted (B6.129-H2dlAb1-Ea/J), or a targeted mutation in the class II transactivator (B6.129S2-C2tatm1Ccum/J). A wide variety of cre-expressing strains, targeted mutants with loxP-flanked genes and tetracycline regulated transactivator-expressing mice are available that require careful selection. Other factors for model selection include mutation characteristics related to mechanism of action, cell types affected, effects of the mutation on breeding and lifespan, and other associated phenotypes. The strain background including breeding performance, MHC haplotype, disease resistance/susceptibilility and known mutations, such as hemolytic complement deficiency found in a subset of inbred strains, could confound results. Supported by NCRR (RR09781, RR11083, RR16049), NIA, HHMI, and donations from several private foundations
10
Bosbach, Dirk, Horst Geckeis, Frank Heberling, Olaf Kolditz, Michael Kühn, Katharina Müller, and Thorsten Stumpf. "An interdisciplinary view of the long-term evolution of repository systems across scales: the iCROSS project." Safety of Nuclear Waste Disposal 1 (November 10, 2021): 85–87. http://dx.doi.org/10.5194/sand-1-85-2021.
Full textAbstract:
Abstract. The interdisciplinary project “Integrity of nuclear waste repository systems – Cross-scale system understanding and analysis (iCROSS)” combines research competencies of Helmholtz scientists related to the topics of nuclear, geosciences, biosciences and environmental simulations in collaborations overarching the research fields energy and earth and environment. The focus is to understand and analyze close-to-real long-term evolutionary pathways of radioactive waste repositories across nanoscales to repository scales. The project is subdivided into work packages dealing with laboratory studies, field experiments in underground research laboratories (URLs), advanced modelling studies and the integration and alignment of data and information using virtual reality methods. In this sense, the project structure aims at a holistic view on relevant processes across scales in order to comprehensively simulate potential repository evolutions. Within the multi-barrier system of a repository for heat-generating radioactive waste, a number of complex reactions proceed, including dissolution, redox processes, biochemical reactions, gas evolution and solid/liquid interface and (co)precipitation reactions. At the same time, thermal and external mechanical stress has an impact on the conditions in a deep geological repository. All those processes are highly coupled, with multiple interdependencies on various scales and have a strong impact on radionuclide mobility and retention. In recent years, substantial progress was achieved in describing coupled thermal-hydro-mechanical-chemical-biological (THM/CB) processes in numerical simulations. A realistic and concise description of these coupled processes on different time and spatial scales is, at present, a largely unresolved scientific and computational challenge. The close interaction of experimental and simulation teams aims at a more accurate quantification and assessment of processes and thus, the reduction of uncertainties and of conservative assumptions and eventually to a close-to-real perception of the repository evolution. One focus of iCROSS is directed to relevant processes in a clay rock repository. In this context, the iCROSS team became a full member of the international Mont Terri consortium and worked in close collaboration with international and German institutions in URL projects. Respective experiments specifically deal with coupled processes at the reactive interfaces in a repository near field (e.g. the steel/bentonite and bentonite/concrete interfaces). Within iCROSS, the impact of secondary phase formation on radionuclide transport is investigated. At Mont Terri, experiments are in preparation to study radionuclide transport phenomena in clay rock formations within temperature gradients and in facies exhibiting significant heterogeneities on different scales (nm to cm). Beside those studies, high resolution exploration methods for rock characterization are developed and tested and the effect of temperature and other boundary conditions on the strength, creep properties and healing of faults within Opalinus clay are quantified. Multiphysics models coupled to reactive transport simulation have been further developed and applied to laboratory and field experiments. Results are digitally analyzed and illustrated in a visualization center, in order to enhance the comprehension of coupled processes in repository systems across scales. The present contribution provides an overview on the project and reports selected results. The impact of considering complex coupled processes in repository subsystems for the assessment of the integrity of a given (generic) repository arrangement is discussed.
11
Popp, Till, Ralf-Michael Günther, and Dirk Naumann. "Suitability of flat bedded salt formations in Germany as the site for a repository for heat-producing radioactive waste." Safety of Nuclear Waste Disposal 1 (November 10, 2021): 43–44. http://dx.doi.org/10.5194/sand-1-43-2021.
Full textAbstract:
Abstract. The search for a site of a final repository for highly radioactive waste in Germany was renewed when the Site Selection Act (StandAG) came into force in 2013. In Germany the development of concepts for a final repository and safety analyses for a repository in a salt dome was prioritized for many decades, whereas repository concepts in clay and crystalline rock were first considered only two decades ago. The aim of a comparative site selection procedure is to find a site before 2031, which provides the best possible safety for the enclosure of highly radioactive waste over a time period of 1 million years. The fundamental safety-related consideration is the enclosure of toxic waste in a so-called containment effective geological area (ewG). The main aspect of a long-term proof of safety is logically the systematic proof of safe long-term enclosure of the deposited waste. The approach developed within the framework of appropriate research projects (e.g. Eickemeier et al., 2013) is essentially based on the proof of geotechnical integrity of the ewG as the fundamental geological barrier as well as the geotechnical barriers. Due to their unique characteristics, including imperviousness and plastic deformability, salt rocks have been used for decades in Germany and worldwide in mining and especially for energy storage. Whereas halite in salt domes (type steep inclined salt) is distributed particularly in northwest Germany, flatly deposited salt rock (type flat bedded salt) dominates in middle Germany and salt pillows (type salt pillows) in parts of northeast Germany. Both types of “bedded salt” widely reflect in their lateral extension sedimentation-related deposition conditions, apart from diagenetically related alterations. Beginning with the presentation of the host rock-specific boundary conditions of the various rock salts, this article focuses on the appropriate procedures for the proof of integrity of the geological barrier rock salt, based on the available experiences, corresponding reference studies and analogous examples. In the results it is shown that repository concepts in bedded salt formations and especially in the constellation of salt pillows provide substantial safety-related advantages due to a site-specific multibarrier system with alternate deposition of salt and saliferous clay as well as an intact overlying rock covering.
12
Omidi, Forouzan, Sayed Abdolhakim Hosseini, Abbas Ahmadi, Kambiz Hassanzadeh, Shima Rajaei, Henry Manuel Cesaire, and Vahedeh Hosseini. "Discovering the signature of a lupus-related microRNA profile in the Gene Expression Omnibus repository." Lupus 29, no. 11 (July 28, 2020): 1321–35. http://dx.doi.org/10.1177/0961203320944473.
Full textAbstract:
Lupus is one of the most prevalent systemic autoimmune diseases. It is a multifactorial disease in which genetic, epigenetic and environmental factors play significant roles. The pathogenesis of lupus is not yet well understood. However, deregulation of microRNAs (miRNAs) – one of the post-transcriptional regulators of genes – can contribute to the development of autoimmune diseases. Over the last two decades, advances in the profiling of miRNA using microarray have received much attention, and it has been demonstrated that miRNAs play a regulatory role in the pathogenesis of lupus. Therefore, dysregulated miRNAs can be considered as promising diagnostic biomarkers for lupus. This article is an overview of lupus-related miRNA profiling studies and arrays in the Gene Expression Omnibus (GEO) database. The aims of our study were to widen current knowledge of known dysregulated miRNAs as potential biomarkers of SLE and to introduce a bioinformatics approach to using microarray data and finding novel miRNA and gene candidates for further study. We identified hsa-miR-4709-5p, hsa-miR-140, hsa-miR-145, hsa-miR-659, hsa-miR-134, hsa-miR-150, hsa-miR-584, hsa-miR-409 and hsa-miR-152 as potential biomarkers by integrated bioinformatics analysis.
13
Kim, Jihyun. "An analysis of data paper templates and guidelines: types of contextual information described by data journals." Science Editing 7, no. 1 (February 20, 2020): 16–23. http://dx.doi.org/10.6087/kcse.185.
Full textAbstract:
Purpose: Data papers are a promising genre of scholarly communication, in which research data are described, shared, and published. Rich documentation of data, including adequate contextual information, enhances the potential of data reuse. This study investigated the extent to which the components of data papers specified by journals represented the types of contextual information necessary for data reuse.Methods: A content analysis of 15 data paper templates/guidelines from 24 data journals indexed by the Web of Science was performed. A coding scheme was developed based on previous studies, consisting of four categories: general data set properties, data production information, repository information, and reuse information.Results: Only a few types of contextual information were commonly requested by the journals. Except data format information and file names, general data set properties were specified less often than other categories of contextual information. Researchers were frequently asked to provide data production information, such as information on the data collection, data producer, and related project. Repository information focused on data identifiers, while information about repository reputation and curation practices was rarely requested. Reuse information mostly involved advice on the reuse of data and terms of use.Conclusion: These findings imply that data journals should provide a more standardized set of data paper components to inform reusers of relevant contextual information in a consistent manner. Information about repository reputation and curation could also be provided by data journals to complement the repository information provided by the authors of data papers and to help researchers evaluate the reusability of data.
14
Kochkin, B. T., S. A. Bogatov, and E. A. Saveleva. "Evolution of the Repository in Nizhnekanskiy Massif under the Influence of Climatic Factors." Radioactive Waste 14, no. 1 (2021): 63–75. http://dx.doi.org/10.25283/2587-9707-2021-1-63-75.
Full textAbstract:
The study identifies climatic factors related to external influences governing the long-term evolution of the RW disposal system at the Yeniseyskiy site. The paper evaluates the current state of knowledge about these factors and indicates most important research areas. These include: paleoclimatic studies in the repository region to clarify the climate history of past geological epochs; quantitative regional climate forecast based on global numerical climate models; special forecasts based on a general climate model of the region allowing, in particular, to clarify the depth of rock mass freezing during ice periods.
15
Krüger, Ralph. "AN ONLINE REPOSITORY OF PYTHON RESOURCE FOR TEACHING MACHINE TRANSLATION TO TRANSLATION STUDENTS." CURRENT TRENDS IN TRANSLATION TEACHING AND LEARNING E 8 (November 15, 2021): 4–30. http://dx.doi.org/10.51287/cttl_e_2021_2_ralph_kruger.pdf.
Full textAbstract:
This paper presents an online repository of Python resources aimed at teaching the technical dimension of machine translation to students of translation studies programmes. The Python resources provided in this repository are Jupyter notebooks. These are web-based computational environments in which students can run commented blocks of code in order to perform MT-related tasks such as exploring word embeddings, preparing MT training data, training open-source machine translation systems or calculating automatic MT quality metrics such as BLEU, METEOR, BERTScore or COMET. The notebooks are prepared in such a way that students can interact with them even if they have had little to no prior exposure to the Python programming language. The notebooks are provided as open-source resources under the MIT License and can be used and modified by translator training institutions which intend to make their students familiar with the more technical aspects of modern machine translation technology. Institutions who would like to contribute their own Python-based teaching resources to the repository are welcome to do so. Keywords: translation technology, machine translation, natural language processing, translation didactics, Jupyter notebooks, Python programming
16
Krüger, Ralph. "AN ONLINE REPOSITORY OF PYTHON RESOURCES FOR TEACHING MACHINE TRANSLATION TO TRANSLATION STUDENTS." Current Trends in Translation Teaching and Learning E 8 (2021): 4–30. http://dx.doi.org/10.51287/cttle20212.
Full textAbstract:
This paper presents an online repository of Python resources aimed at teaching the technical dimension of machine translation to students of translation studies programmes. The Python resources provided in this repository are Jupyter notebooks. These are web-based computational environments in which students can run commented blocks of code in order to perform MT-related tasks such as exploring word embeddings, preparing MT training data, training open- source machine translation systems or calculating automatic MT quality metrics such as BLEU, METEOR, BERTScore or COMET. The notebooks are prepared in such a way that students can interact with them even if they have had little to no prior exposure to the Python programming language. The notebooks are provided as open-source resources under the MIT License and can be used and modified by translator training institutions which intend to make their students familiar with the more technical aspects of modern machine translation technology. Institutions who would like to contribute their own Python-based teaching resources to the repository are welcome to do so. Keywords: translation technology, machine translation, natural language processing, translation didactics, Jupyter notebooks, Python programming
17
Han, Yan. "ETD: total cost of ownership – collecting, archiving and providing access." Library Management 35, no. 4/5 (June 3, 2014): 250–58. http://dx.doi.org/10.1108/lm-08-2013-0084.
Full textAbstract:
Purpose – The purpose of this paper is to provide a case study of total cost of ownership (TOC) for Electronic Theses and Dissertations (ETD). Only few articles have been published to discuss the costs associated with repository and/or theses and dissertations (TD). Design/methodology/approach – The paper first provides literature reviews in costs associated with repository and TD. By using the DCC life cycle model, the author presents costs for each actionable category: create or receive, appraise & select, ingest, preservation action, store, access, use and reuse and transform. The paper presents four TOCs to illustrate the changes of TOCs from 2005 to current time. Findings – The paper gives one case study of the TOCs for ETD over the years, and illustrates how the University lowered the TOCs. The current ETD's TOC is on a par with these costs of two other studies published related to repository titles. The TOC has been decreased from the traditional paper-based TD of $75 per title to ETD of $69 in 2005. By removing the ProQuest processing fee of $55, the TOC decreased to $14.37 in 2010. The TOC is currently $6.33 per title after the ETD collection was migrated to the University of Arizona repository. Research limitations/implications – Readers shall be aware that there are no “transform” and little “preservation action” tasks performed. The current cost of “transform” is $0 due to the nature of ETD of its rigid format requirements, Originality/value – The paper fulfills the need to study costs associated with repository titles, especially ETD titles. It also provide a way to estimate costs for institutions planning to start ETD collections.
18
Parker, Quentin A., Ivan Bojičić, and David J. Frew. "Exploiting the HASH Planetary Nebula Research Platform." Proceedings of the International Astronomical Union 12, S323 (October 2016): 36–39. http://dx.doi.org/10.1017/s1743921317000904.
Full textAbstract:
AbstractThe HASH (Hong Kong/ AAO/ Strasbourg/ Hα) planetary nebula research platform is a unique data repository with a graphical interface and SQL capability that offers the community powerful, new ways to undertake Galactic PN studies. HASH currently contains multi-wavelength images, spectra, positions, sizes, morphologies and other data whenever available for 2401true, 447likely, and 692possibleGalactic PNe, for a total of 3540 objects. An additional 620 Galactic post-AGB stars, pre-PNe, and PPN candidates are included. All objects were classified and evaluated following the precepts and procedures established and developed by our group over the last 15 years. The complete database contains over 6,700 Galactic objects including the many mimics and related phenomena previously mistaken or confused with PNe. Curation and updating currently occurs on a weekly basis to keep the repository as up to date as possible until the official release of HASH v1 planned in the near future.
19
Syarifah, Lilis, Imas Sukaesih Sitanggang, and Pudji Muljono. "ANALYSIS OF THESIS ADVISING PATTERN IN MASTER PROGRAM ON FACULTY OF AGRICULTURE IPB USING DATA MINING APPROACH." Edulib 8, no. 2 (December 1, 2018): 194. http://dx.doi.org/10.17509/edulib.v8i2.12321.
Full textAbstract:
The thesis is student study report which is accomplished as a requirement of graduation for Master program. Selecting study’s topic and advisors influence implementation of the study. Therefore, study’s topic is able to improve academic institution quality, however a large number of thesis documents on the repository cause difficulty to get information related to advisor’s expertness and the frequent or rare topic is former studied. Association rule mining can be used to mine information on the related item. This study aims to analyze advising patterns system in Master program on Agriculture based on supervisors and their topic research on metadata thesis of IPB repository and text documents of summary using data mining approach. The datas were collected from the repository of Bogor Agricultural University website and processed using R language programming. Pattern result of the reseach were that the most popular association on supervisor was occurred at support value of 0.00793 or equivalent to 7 theses and four popular topics were Botanical insecticide, Global warming, Upland Rice, and Land Use Change. The analysis result could be useful information to be reference or suggest future research or appropriate supervisor among agricultural.
20
De Giusti, Marisa R., Gonzalo L. Villarreal, Carlos J. Nusch, Analía V. Pinto, and Ariel J. Lira. "Open access and open data on natural disasters." IFLA Journal 43, no. 1 (December 19, 2016): 81–88. http://dx.doi.org/10.1177/0340035216678236.
Full textAbstract:
After a flood which devastated the city of La Plata (Argentina) in April 2013, a survey of the water situation in the region revealed that relevant studies and projects related with this area were scattered and lacked visibility. This prompted academic, scientific, technologic, and governmental institutions to take action and work together to compile, organize, and disseminate available data in an unprecedented response to an environmental disaster in the region. For this purpose, a dedicated collection was created in the SEDICI, the institutional repository for the Universidad Nacional de La Plata, and subsequently, the Observatorio Medioambiental La Plata (OMLP), a repository for data on environmental research, was launched. This document describes these collaboration initiatives which aim to anticipate and reduce the impact of natural disasters, their main characteristics, their resources, and their current progress. Projects driven by the OMLP are also described, along with a description of their technical and infrastructure deployment as per the open access policies.
21
Turner, Simon L., Amalia Karahalios, Andrew B. Forbes, Monica Taljaard, Jeremy M. Grimshaw, Allen C. Cheng, Lisa Bero, and Joanne E. McKenzie. "Design characteristics and statistical methods used in interrupted time series studies evaluating public health interventions: protocol for a review." BMJ Open 9, no. 1 (January 2019): e024096. http://dx.doi.org/10.1136/bmjopen-2018-024096.
Full textAbstract:
IntroductionAn interrupted time series (ITS) design is an important observational design used to examine the effects of an intervention or exposure. This design has particular utility in public health where it may be impracticable or infeasible to use a randomised trial to evaluate health system-wide policies, or examine the impact of exposures (such as earthquakes). There have been relatively few studies examining the design characteristics and statistical methods used to analyse ITS designs. Further, there is a lack of guidance to inform the design and analysis of ITS studies.This is the first study in a larger project that aims to provide tools and guidance for researchers in the design and analysis of ITS studies. The objectives of this study are to (1) examine and report the design characteristics and statistical methods used in a random sample of contemporary ITS studies examining public health interventions or exposures that impact on health-related outcomes, and (2) create a repository of time series data extracted from ITS studies. Results from this study will inform the remainder of the project which will investigate the performance of a range of commonly used statistical methods, and create a repository of input parameters required for sample size calculation.Methods and analysisWe will collate 200 ITS studies evaluating public health interventions or the impact of exposures. ITS studies will be identified from a search of the bibliometric database PubMed between the years 2013 and 2017, combined with stratified random sampling. From eligible studies, we will extract study characteristics, details of the statistical models and estimation methods, effect metrics and parameter estimates. Further, we will extract the time series data when available. We will use systematic review methods in the screening, application of inclusion and exclusion criteria, and extraction of data. Descriptive statistics will be used to summarise the data.Ethics and disseminationEthics approval is not required since information will only be extracted from published studies. Dissemination of the results will be through peer-reviewed publications and presentations at conferences. A repository of data extracted from the published ITS studies will be made publicly available.
22
van den Akker, Erik B., Stella Trompet, Jurriaan J. H. Barkey Wolf, Marian Beekman, H. Eka D. Suchiman, Joris Deelen, Folkert W. Asselbergs, et al. "Metabolic Age Based on the BBMRI-NL 1 H-NMR Metabolomics Repository as Biomarker of Age-related Disease." Circulation: Genomic and Precision Medicine 13, no. 5 (October 2020): 541–47. http://dx.doi.org/10.1161/circgen.119.002610.
Full textAbstract:
Background: The blood metabolome incorporates cues from the environment and the host’s genetic background, potentially offering a holistic view of an individual’s health status. Methods: We have compiled a vast resource of proton nuclear magnetic resonance metabolomics and phenotypic data encompassing over 25 000 samples derived from 26 community and hospital-based cohorts. Results: Using this resource, we constructed a metabolomics-based age predictor (metaboAge) to calculate an individual’s biological age. Exploration in independent cohorts demonstrates that being judged older by one’s metabolome, as compared with one’s chronological age, confers an increased risk on future cardiovascular disease, mortality, and functionality in older individuals. A web-based tool for calculating metaboAge ( metaboage.researchlumc.nl ) allows easy incorporation in other epidemiological studies. Access to data can be requested at bbmri.nl/samples-images-data . Conclusions: In summary, we present a vast resource of metabolomics data and illustrate its merit by constructing a metabolomics-based score for biological age that captures aspects of current and future cardiometabolic health.
23
Elias, Brenda, Ana Hanlon-Dearman, Betty Head, and Geoffrey G. Hicks. "Translating to the Community (T2C): a protocol paper describing the development of Canada’s first social epigenetic FASD biobank." Biochemistry and Cell Biology 96, no. 2 (April 2018): 275–87. http://dx.doi.org/10.1139/bcb-2017-0278.
Full textAbstract:
Translating to the Community (T2C) is a social biorepository designed to advance new diagnostic tools and realign community–clinical processes, with the aim to mitigate the short- and long-term impacts of fetal alcohol spectrum disorder (FASD) as well as prenatal alcohol exposure and its co-morbidities and behaviors. In this paper, we describe the evolution of this repository as a new translational partnership to advance a precision-medicine approach to FASD. Key to its evolution was a partnership between academic researchers, Indigenous communities, families, and a regional diagnostic clinic. We further describe the rationale for social biobanking, the type of banking, ethical engagement of families, communities, and clinics, their roles in repository design, governance, translation, and research activities, types of data collected from families, and how the study data are managed, reported, and accessed. The repository design includes biological samples, social-contextual health-survey data, and clinical data (which are linkable to administrative data) from community and clinical cohorts of diagnosed children, children prenatally exposed but not diagnosed, children suspected to have had a prenatal exposure, and related siblings, biological parents, and unrelated children and their parents. From these cohorts and families, potential studies drawing on this data will shed light on various risk factors, social and biological pathways, and service utilization issues, with the aim to implement primary and secondary prevention and intervention strategies.
24
Szamreta, Elizabeth A., Mansi Modi, Ramu Periyasamy, Bhavani Yamsani, Sumedha Kulkarni, and Matthew J. Monberg. "Systematic review of real-world evidence studies in women’s cancer at key congresses and factors related to high tier acceptance." Journal of Clinical Oncology 40, no. 16_suppl (June 1, 2022): e17533-e17533. http://dx.doi.org/10.1200/jco.2022.40.16_suppl.e17533.
Full textAbstract:
e17533 Background: Real-world evidence (RWE) studies complement clinical trials (CT) and address a variety of issues, such as adherence, cost, comparative effectiveness, and treatment patterns. This systematic review assessed prevalence and characteristics of RWE presented at oncology congresses. Methods: Data on women’s cancers (cervical, ovarian, endometrial, and multiple [gyn/other]) work were extracted from the databases of American Society of Clinical Oncology (ASCO) and The Society of Gynecological Oncology (SGO) congresses (2018-2020). The primary objective was to identify the proportion of CT vs RWE. Secondary objectives were to: a) describe the tier of acceptance for RWE vs CTs; b) describe prevalence of types of RWE; c) analyze the characteristics (data source, design, authorship, outcome(s) assessed, and presence of statistically significant results) associated with RWE acceptance. Results: Of 3163 abstracts screened, 2271 were included (1756 RWE vs 515 CTs). RWE represented a higher proportion of work at SGO vs ASCO (90% vs 59%). Overall, more RWE vs CTs was accepted as a poster (75% vs 60%) or publication only (19% vs 11%), while less was accepted for oral presentation (4% vs 20%). Among RWE, 90% had academic author(s), 44% used clinical data, around one quarter used another data repository/registry, and about 14% used medical record or chart review data. Nearly two thirds of RWE studies reported significant results, while 6% contained no significant results. There was no clear association between authorship or significance of results and tier of acceptance. About 60% of RWE studies were retrospective, 9% were prospective, 4% focused primarily on PROs, and 2% were economic models. The most common outcomes assessed in RWE studies were molecular analyses (18%) and survival based on treatment efficacy (13%). Among molecular analyses, most (68%) were accepted as a poster, with 26% accepted as publication only and 4% as oral. An even greater fraction (77%) of survival/efficacy analyses were accepted as a poster, 18% as publication only and even fewer (2%) as oral. Conclusions: RWE was more frequently presented than CTs at both ASCO and SGO. However, across congresses and cancer types, a smaller proportion of RWE vs CT work was accepted as an oral presentation. Results indicated high interest in CTs; RWE studies utilizing clinical data or data repository/registry data, and those with molecular and/or survival outcomes, were most common. The results demonstrate that while RWE studies are prevalent and provide valuable data for healthcare decision-making, they do not always achieve the visibility of CTs.[Table: see text]
25
Szamreta, Elizabeth A., Mansi Modi, Ramu Periyasamy, Bhavani Yamsani, Sumedha Kulkarni, and Matthew J. Monberg. "Systematic review of real-world evidence studies in women’s cancer at key congresses and factors related to high tier acceptance." Journal of Clinical Oncology 40, no. 16_suppl (June 1, 2022): e17533-e17533. http://dx.doi.org/10.1200/jco.2022.40.16_suppl.e17533.
Full textAbstract:
e17533 Background: Real-world evidence (RWE) studies complement clinical trials (CT) and address a variety of issues, such as adherence, cost, comparative effectiveness, and treatment patterns. This systematic review assessed prevalence and characteristics of RWE presented at oncology congresses. Methods: Data on women’s cancers (cervical, ovarian, endometrial, and multiple [gyn/other]) work were extracted from the databases of American Society of Clinical Oncology (ASCO) and The Society of Gynecological Oncology (SGO) congresses (2018-2020). The primary objective was to identify the proportion of CT vs RWE. Secondary objectives were to: a) describe the tier of acceptance for RWE vs CTs; b) describe prevalence of types of RWE; c) analyze the characteristics (data source, design, authorship, outcome(s) assessed, and presence of statistically significant results) associated with RWE acceptance. Results: Of 3163 abstracts screened, 2271 were included (1756 RWE vs 515 CTs). RWE represented a higher proportion of work at SGO vs ASCO (90% vs 59%). Overall, more RWE vs CTs was accepted as a poster (75% vs 60%) or publication only (19% vs 11%), while less was accepted for oral presentation (4% vs 20%). Among RWE, 90% had academic author(s), 44% used clinical data, around one quarter used another data repository/registry, and about 14% used medical record or chart review data. Nearly two thirds of RWE studies reported significant results, while 6% contained no significant results. There was no clear association between authorship or significance of results and tier of acceptance. About 60% of RWE studies were retrospective, 9% were prospective, 4% focused primarily on PROs, and 2% were economic models. The most common outcomes assessed in RWE studies were molecular analyses (18%) and survival based on treatment efficacy (13%). Among molecular analyses, most (68%) were accepted as a poster, with 26% accepted as publication only and 4% as oral. An even greater fraction (77%) of survival/efficacy analyses were accepted as a poster, 18% as publication only and even fewer (2%) as oral. Conclusions: RWE was more frequently presented than CTs at both ASCO and SGO. However, across congresses and cancer types, a smaller proportion of RWE vs CT work was accepted as an oral presentation. Results indicated high interest in CTs; RWE studies utilizing clinical data or data repository/registry data, and those with molecular and/or survival outcomes, were most common. The results demonstrate that while RWE studies are prevalent and provide valuable data for healthcare decision-making, they do not always achieve the visibility of CTs.[Table: see text]
26
Vietor, Tim, and Michael Schnellmann. "Site selection for the best clay-hosted repository in Switzerland." Safety of Nuclear Waste Disposal 1 (November 10, 2021): 51–52. http://dx.doi.org/10.5194/sand-1-51-2021.
Full textAbstract:
Abstract. The site selection process for the deep geological repositories in Switzerland is in its final phase. All three remaining sites fulfil the requirements of the repositories for low level waste (LLW) as well as for high level waste (HLW) and spent fuel. Using surface-based exploration methods, including 3D seismic studies and deep bore holes, Nagra has recently collected the necessary data to select the most suitable site. The sites will be compared based on 13 technical criteria defined in 2008 and already used in the 2 previous phases of the selection process. The criteria comprise safety-related aspects including the barrier properties and their long-term stability as well as the construction suitability of the repository and its access facilities. If one site offers optimal conditions for both HLW and LLW and the space requirements can be met at that site, a co-disposal facility will be proposed. This facility will then comprise separate emplacement areas with specific safety concepts for the different waste categories. In our contribution we present the overall approach for the surface-based exploration in the different stages of the site selection process. We show how we integrated third party data, seismic surveys, surface mapping as well as deep and shallow bore holes to drive the site selection process. Example data sets from the ongoing deep drilling campaign (clay content, hydrotest data, porewater isotope profiles etc.) and recent 3D seismic surveys are used to illustrate our approach to distinguish the remaining sites according to long-term safety and to underline the large safety margin of the selected clay host rock in long-term evolution scenarios.
27
von Schenck, Henrik, Ulrik Kautsky, Björn Gylling, Elena Abarca, and Jorge Molinero. "Advancing the Modelling Environment for the Safety Assessment of the Swedish LILW Repository at Forsmark." MRS Proceedings 1744 (2015): 223–28. http://dx.doi.org/10.1557/opl.2015.348.
Full textAbstract:
ABSTRACTAn extension of the Swedish final repository for short-lived radioactive waste (SFR) is planned and a safety assessment has been performed as part of the licensing process. Within this work, steps have been taken to advance the modelling environment to better integrate its individual parts. It is desirable that an integrating modelling environment provides the framework to set up and solve a consistent hierarchy of models on different scales. As a consequence, the consistent connection between software tools and models needs to be considered, related to the full assessment domain. It should also be possible to include the associated geometry and material descriptions, minimizing simplifications of conceptual understanding.The usefulness of the analysis software Comsol Multiphysics as component of an integrating modelling environment has been tested. Here, we present two examples of hierarchical models. Consistent properties and boundary conditions have been extracted form regional hydrogeology and surface hydrology models when setting up repository scale models. CAD models of the repository have been imported into the analysis software, representing tunnel systems and storage vaults with engineered structures and barriers. Data from geographic information systems such as digital elevation models and geological formations have been also directly implemented into model geometries.The repository scale hydrology models have provided a basis for further developments focussed on the modelling of coupled processes. An interface between Comsol Multiphysics and the geochemical simulator Phreeqc has been developed to support reactive solute transport studies. An important test case concerns radionuclide transport in a 3D, near-surface model of a catchment area. The dynamic surface hydrology has been simulated with MIKE SHE and connected to Comsol Multiphysics and Phreeqc for detailed hydro-geo-chemical modelling of radionuclide migration through soils and sediments.
28
Finsterle, Stefan, Richard A. Muller, John Grimsich, Ethan A. Bates, and John Midgley. "Post-Closure Safety Analysis of Nuclear Waste Disposal in Deep Vertical Boreholes." Energies 14, no. 19 (October 5, 2021): 6356. http://dx.doi.org/10.3390/en14196356.
Full textAbstract:
Isolation of spent nuclear fuel assemblies in deep vertical boreholes is analyzed. The main safety features of the borehole concept are related to the repository’s great depth, implying (a) long migration distances and correspondingly long travel times, allowing radionuclides to decay, (b) separation of the repository from the dynamic hydrological cycle near the land surface, (c) stable geological and hydrogeological conditions, and (d) a geochemically reducing environment. An integrated simulation model of the engineered and natural barrier systems has been developed to examine multiple scenarios of the release of radionuclides from the waste canisters, the transport through a fractured porous host rock, and the extraction of potentially contaminated drinking water from an aquifer. These generic simulations include thermal effects from both the natural geothermal gradient and the heat-generating waste, the influence of topography on regional groundwater flow, moderated by salinity stratification at depth, and the role of borehole sealing. The impact of these processes on the transport of select radionuclides is studied, which include long-lived, soluble, sorbing or highly mobile isotopes along with a decay chain of safety-relevant actinide metals. The generic analyses suggest that a deep vertical borehole repository has the potential to be a safe option for the disposal of certain waste streams, with the depth itself and the stable hydrogeological environment encountered in the emplacement zone providing inherent long-term isolation, which allows for reduced reliance on a complex engineered barrier system.
29
Wood, Clinton M., and Brady R. Cox. "Experimental Data Set of Mining-Induced Seismicity for Studies of Full-Scale Topographic Effects." Earthquake Spectra 31, no. 1 (February 2015): 541–64. http://dx.doi.org/10.1193/020314eqs026.
Full textAbstract:
This paper describes two large, high-quality experimental data sets of ground motions collected with locally dense arrays of seismometers deployed on steep mountainous terrain with varying slope angles and topographic features. These data sets were collected in an area of central-eastern Utah that experiences frequent and predictable mining-induced seismicity as a means to study the effects of topography on small-strain seismic ground motions. The data sets are freely available through the George E. Brown, Jr. Network for Earthquake Engineering Simulation data repository ( NEEShub.org ) under the DOI numbers 10.4231/D34M9199S and 10.4231/D3Z31NN4J. This paper documents the data collection efforts and metadata necessary for utilizing the data sets, as well as the availability of supporting data (e.g., high-resolution digital elevation models). The paper offers a brief summary of analyses conducted on the data sets thus far, in addition to ideas about how these data sets may be used in future studies related to topographic effects and mining seismicity.
30
Fellhauer, David, Xavier Gaona, Marcus Altmaier, and Horst Geckeis. "Radionuclide geochemistry: solubility and thermodynamics in an HLW repository." Safety of Nuclear Waste Disposal 1 (November 10, 2021): 149–50. http://dx.doi.org/10.5194/sand-1-149-2021.
Full textAbstract:
Abstract. Deep geological disposal is the internationally favoured option to isolate high-level nuclear waste (HLW) from the biosphere and to minimise the potential radiological risk for future generations. Potentially contacting aqueous solutions such as groundwater may, however, lead to the corrosion of the solid casks containing the nuclear waste, and the formation of aqueous radionuclide systems in the near-field of the emplacement rooms. As dissolved species, radionuclides can in principle further migrate into the far-field and finally reach the biosphere on medium and long timescales. Like all chemical species, the radionuclides are subject to fundamental (geo)chemical laws. Relevant reactions that control retention and release, and hence, the migration behaviour and fate of radionuclides in a repository, are solubility equilibria, formation of soluble complexes, redox reactions, sorption on and incorporation into mineral surfaces, transport phenomena etc. These processes depend directly on the (geo)chemical boundary conditions, and, consequently, can differ greatly for various host rock systems such as clay rock, rock salt, and crystalline rock. Many of the radionuclides in HLW are heavy metals that are sparingly soluble under various repository-relevant conditions, e.g. actinides, lanthanides, transition metals, so that only partial dissolution (mobilisation) from the solid waste matrices is expected. This underlines the importance of evaluating the radionuclide solubility within a geochemically based safety assessment for repositories as it provides reliable upper-limit concentrations of the mobile, potentially migrating radionuclide fraction in the near-field. In this contribution, we discuss relevant aspects related to the topic radionuclide solubility and thermodynamics in a HLW repository. This includes a summary of recent laboratory studies on the solubility behaviour and speciation of key radionuclides in repository-relevant solutions, which are an important basis for obtaining (geo)chemical information and models, and the corresponding fundamental thermodynamic constants on aqueous radionuclide systems. National and international thermodynamic database projects, where quality-assured thermodynamic data (solubility products, complex formation constants, and ion-interaction parameters) are evaluated and compiled, e.g. the Nuclear Energy Agency Thermochemical Database (http://www.oecd-nea.org, last access: 1 November 2021) or the Thermodynamic Reference Database (http://www.thereda.de, last access: 1 November 2021), are highlighted and the main remaining uncertainties discussed. The experimental information and the quantitative thermodynamic data are applied within a generic case study to demonstrate the impact of different geochemical solution conditions representing different host rock systems considered as HLW repositories in Germany on the solubility and speciation of selected radionuclides.
31
Ma, Zhanguo, Lei Xu, Peng Gong, Yongheng Chen, and Lei Zhang. "The thermal expansion characteristics of mudstone." Thermal Science 23, no. 6 Part B (2019): 3731–37. http://dx.doi.org/10.2298/tsci180718242m.
Full textAbstract:
The location of mudstone rock formations as a repository of radioactive materials has attracted great attention from the international rock mechanics community. In this paper, the strain and thermal expansion coefficient of mudstone during the heating and constant temperature stages are studied through experiments. The results can provide a scientific basis for the design and safety protection of related projects.
32
Farida, Ida, Jann Hidajat Tjakraatmadja, Aries Firman, and Sulistyo Basuki. "A conceptual model of Open Access Institutional Repository in Indonesia academic libraries." Library Management 36, no. 1/2 (January 12, 2015): 168–81. http://dx.doi.org/10.1108/lm-03-2014-0038.
Full textAbstract:
Purpose – The purpose of this paper is to attempt to build a conceptual model of Open Access Institutional Repositories (OAIR) in Indonesia academic libraries, viewed from knowledge management (KM) perspective. Design/methodology/approach – Literature-based conceptual analysis of previous studies related to open access, institutional repositories viewed from KM perpective. Findings – The conceptual model of OAIR emphasizes three variables – people collaboration, process, and technology functions. These variables, with their many elements, are integrated together in order to help the university or Higher Education (HE) institution in capturing its own scholarship produced as a whole. Besides, that integration aims at facilitating knowledge sharing so as to enrich knowledge content and to enhance global access. A process chart of OAIR based on the conceptual model is built to illustrate knowledge content recruitment in Indonesia academic libraries. Research limitations/implications – The conceptual model proposed in this paper is not yet formally tested. It needs more research to understand the Indonesian context of OAIR to build a more accurate model, based on the experiences in developing and implementing OAIR in Indonesia HE institutions. Originality/value – Many academic libraries in Indonesia develop OAIR to increase the visibility of the scholarship of the parent HE institution. It is significant to view the practice of OAIR in academic library from the KM perspective. KM implementation is almost unheard of in Indonesia universities. However, The OAIR phenomenon in Indonesia academic libraries can be viewed as a KM initiative.
33
Devoie, Élise G., Stephan Gruber, and Jeffrey M. McKenzie. "A repository of measured soil freezing characteristic curves: 1921 to 2021." Earth System Science Data 14, no. 7 (July 20, 2022): 3365–77. http://dx.doi.org/10.5194/essd-14-3365-2022.
Full textAbstract:
Abstract. Soil freeze–thaw processes play a fundamental role in the hydrology, geomorphology, ecology, thermodynamics, and soil chemistry of cold regions' landscapes. In understanding these processes, the temperature of the soil is used as a proxy to represent the partitioning of soil ice and water content via a soil freezing characteristic curve (SFCC). This mathematical construct relates the soil ice content to a specific temperature for a particular soil. SFCCs depend on many factors, including soil properties (e.g., porosity and composition), soil pore water pressure, dissolved salts, (hysteresis in) freezing/thawing point depression, and the degree of saturation, all of which can be site-specific and time-varying characteristics. SFCCs have been measured using various methods for diverse soils since 1921, but, to date, these data have not been broadly compared. This is in part because they had not previously been compiled in a single dataset. The dataset presented in this publication includes SFCC data digitized or received from authors, and it includes both historic and modern studies. The data are stored in an open-source repository, and an R package is available to facilitate their use. Aggregating the data has pointed out some data gaps, namely that there are few studies on coarse soils and comparably few in situ measurements of SFCCs in mountainous environments. It is hoped that this dataset (https://doi.org/10.5281/zenodo.5592825; Devoie et al., 2022a) will aid in the development of SFCC theory and improve SFCC approximations in soil freeze–thaw modelling activities.
34
Kozono, David E., Elad Sharon, Jennifer Le-Rademacher, Erin Twohy, Tyler J. Zemla, Yujia Wen, Mark Watson, et al. "Alliance A151804: Establishment of a national biorepository to advance studies of immune-related adverse events." Journal of Clinical Oncology 38, no. 15_suppl (May 20, 2020): TPS3154. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.tps3154.
Full textAbstract:
TPS3154 Background: Immune-related Adverse Events (irAEs) are rare but serious sequelae of treatment with immuno-oncology (IO) therapeutics. These therapeutics, including monoclonal antibodies targeting programmed cell death protein 1 (PD-1), programmed death-ligand 1 (PD-L1) and cytotoxic T-lymphocyte-associated protein 4 (CTLA-4), have had transformative effects on outcomes for patients (pts) with advanced cancers. Although most pts tolerate the therapies well, a few experience irAEs ranging in severity up to life-threatening. These irAEs involve diverse organs including the heart, kidney, liver and lung, and gastrointestinal, musculoskeletal, central and peripheral nervous systems. Because of the relatively low incidence and wide variety of irAEs due to various immunotherapies for multiple tumor types, establishment of an efficient centralized repository for acquisition and organized distribution of well-annotated biospecimens is vital for translational studies that improve understanding of the molecular pathogenesis and treatment of these significant toxicities. Methods: This multi-institutional study is open at sites across the National Clinical Trial Network to pts who received ≥ 1 IO therapeutics (e.g., CTLA-4, PD-1 or PD-L1 inhibitor) and experienced 1) ≥ 1 serious (grade 3–5) adverse events that are likely immune-related, 2) rare infection or 3) tumor hyperprogression. IrAEs of interest include myocarditis, colitis, hepatitis, nephritis, myositis, pneumonitis, meningitis/encephalitis, dermatitis, endocrinopathies and neuropathy. Pts may be on an NCTN or non-NCTN IO trial or be receiving standard-of-care therapy. Registration must occur ≤ 72 hours after confirmation of the irAE event. Clinical data are collected at registration, 1 month after registration and for up to 1 year. Biospecimens (tumor blocks, biopsies of inflammatory tissues used to establish irAE diagnosis, and serial blood samples for isolation of plasma, serum and peripheral blood mononuclear cells) are collected at 1-2 timepoints. Stool samples are collected from pts experiencing colitis. Imaging data are collected for pts with hyperprogression or pneumonitis. Goal accrual is 240 pts. Biospecimens and data will be made available to investigators following future submission and approval of proposals. Support: U10CA180821, U10CA180882, U24CA196171; U10CA180820 (ECOG-ACRIN); U10CA180888 (SWOG); U10CA180868 (NRG); https://acknowledgments.alliancefound.org; Clinical trial information: NCT04242095 .
35
Fernandez-Cerado, Cara, G. Paul Legarda, M. Salvie Velasco-Andrada, Abegail Aguil, Niecy G. Ganza-Bautista, J. Benedict B. Lagarde, Jasmin Soria, et al. "Promise and challenges of dystonia brain banking: establishing a human tissue repository for studies of X-Linked Dystonia-Parkinsonism." Journal of Neural Transmission 128, no. 4 (January 13, 2021): 575–87. http://dx.doi.org/10.1007/s00702-020-02286-9.
Full textAbstract:
AbstractX-Linked Dystonia-Parkinsonism (XDP) is a neurodegenerative disease affecting individuals with ancestry to the island of Panay in the Philippines. In recent years there has been considerable progress at elucidating the genetic basis of XDP and candidate disease mechanisms in patient-derived cellular models, but the neural substrates that give rise to XDP in vivo are still poorly understood. Previous studies of limited XDP postmortem brain samples have reported a selective dropout of medium spiny neurons within the striatum, although neuroimaging of XDP patients has detected additional abnormalities in multiple brain regions beyond the basal ganglia. Given the need to fully define the CNS structures that are affected in this disease, we created a brain bank in Panay to serve as a tissue resource for detailed studies of XDP-related neuropathology. Here we describe this platform, from donor recruitment and consent to tissue collection, processing, and storage, that was assembled within a predominantly rural region of the Philippines with limited access to medical and laboratory facilities. Thirty-six brains from XDP individuals have been collected over an initial 4 years period. Tissue quality was assessed based on histologic staining of cortex, RNA integrity scores, detection of neuronal transcripts in situ by fluorescent hybridization chain reaction, and western blotting of neuronal and glial proteins. The results indicate that this pipeline preserves tissue integrity to an extent compatible with a range of morphologic, molecular, and biochemical analyses. Thus the algorithms that we developed for working in rural communities may serve as a guide for establishing similar brain banks for other rare diseases in indigenous populations.
36
Meyers, Timothy W. "Literature Synthesis on Evaluative Measures in Healthcare Simulation." International Journal of Gaming and Computer-Mediated Simulations 4, no. 3 (July 2012): 38–48. http://dx.doi.org/10.4018/jgcms.2012070103.
Full textAbstract:
Whereas most educators have a good grasp on the history of simulation in healthcare, the current state and types of modalities related to simulation in healthcare education, and the future direction of healthcare simulation, many educators do not have an in-depth understanding of the metrics available to assess the use of simulation. The purpose of this literature synthesis is to build a repository of the metrics being used to evaluate nursing and healthcare provider simulation. Additionally, the level of fidelity and desired learning domains that the matrices purport to evaluate is examined. A secondary purpose of the literature synthesis is to determine if a suitable metric is available that can be used universally to evaluate nursing and healthcare related simulations. Finally, conceptual frameworks suitable for serving as the bases of instrument development related to nursing and health care simulation are explored. Primary studies, meta-analyses, and systematic reviews that discussed or evaluated metrics used to measure outcomes of simulation were analyzed. Recent articles, published within the last five years, which discussed the evaluation of nursing and or healthcare simulation, were eligible for inclusion. Additionally, descriptive, inferential, qualitative, and quantitative studies were eligible for inclusion.
37
Safitri, Riri, Muhammad Surya Gemilang, and Denny Hermawan. "Repository Portofolio TA Mahasiswa Teknik Informatika UAI." JURNAL Al-AZHAR INDONESIA SERI SAINS DAN TEKNOLOGI 4, no. 1 (January 31, 2018): 18. http://dx.doi.org/10.36722/sst.v4i1.243.
Full textAbstract:
<p><em>Abstra</em><em>k</em> – <strong>Tugas Akhir (TA) merupakan tahapan terakhir yang harus dilalui oleh setiap mahasiswa untuk menjadi sarjana. TA merupakan suatu bentuk implementasi mahasiswa terhadap ilmu-ilmu yang telah dipelajari selama perkuliahan untuk menyelesaikan suatu permasalahan. Di Universitas Al Azhar Indonesia, khususnya prodi Teknik Informatika, buku laporan TA yang telah dikumpulkan disimpan di Sekretariat Fakultas dan perpustakaan Universitas, sedangkan CD laporan TA disimpan di laboratorium. CD yang disimpan di laboratorium semakin hari semakin banyak dan tidak dimanfaatkan dengan baik. Mahasiswa yang membutuhkan informasi terkait dengan penelitian yang akan dilakukan akan datang ke perpustakaan dan membaca buku laporan TA yang tersimpan. Mahasiswa juga dapat melihat abstrak dan <em>file</em> TA di <em>website</em> perpustakaan, tapi terbatas untuk laporan TA dengan nilai A. Untuk memberikan kemudahan dalam menyimpan dan mendapatkan informasi mengenai TA, maka dibuatlah sebuah repository portofolio TA mahasiswa. Melalui repository ini mahasiswa dapat melihat laporan TA dari seluruh lulusan Teknik Informatika UAI berupa poster dan <em>screen shoot </em>aplikasi atau hasil penelitian yang telah dilakukan. Dengan adanya repository ini, membantu prodi Teknik Informatika dalam menyimpan data-data mengenai laporan TA mahasiswa dengan baik dan terawat. Repository ini juga memberikan kemudahan kepada mahasiswa untuk mendapatkan referensi penelitian yang telah dilakukan sebelumnya dari banyak laporan TA melalui satu aplikasi.</strong><strong></strong></p><p> </p><p><strong><em>K</em></strong><strong><em>ata Kunci </em></strong>– <em>R</em><em>e</em><em>positor</em><em>i</em>, <em>Portofolio, TA, </em><em>P</em><em>erguruan </em><em>T</em><em>inggi</em>, <em>W</em><em>eb </em><em>B</em><em>ased</em> <em>A</em><em>pplication</em>.<em> </em><em></em></p><p> </p><p><em>Abstract</em> - <strong>Final Project is the last stage that must be passed by every student to become a scholar. Final project is a form of student implementation of the sciences that have been studied during the lecture to solve a problem. At the University of Al Azhar Indonesia, especially Informatics Engineering Department, the book of collected final project reports is stored in the Faculty and University Library Secretariat, while the final project report CD is stored in the laboratory. CD stored in the laboratory are getting more and more and are not being utilized properly. Students who need information related to the research to be conducted will come to the library and read the book of the stored final project reports. Students can also view abstracts and final project files on library websites, but are limited to final project reports with a value. To provide ease in storing and getting information about final project, then made a repository of final project portfolio of students. Through this repository, students can view final project reports from all UAI Informatics Engineering graduates in the form of poster and screen shoot application or research result that has been done. This repository also makes it easy for students to get research references that have been done before from many final project reports through one application.</strong></p><p><strong> </strong></p><strong><em>Keyword </em></strong><em>– Repository, Portofolio, Final Project, University, Web Based Application.</em>
38
Samedy, Patrick. "Design, implementation, and assessment of a metrics management system for quality improvement studies." Journal of Clinical Oncology 31, no. 31_suppl (November 1, 2013): 34. http://dx.doi.org/10.1200/jco.2013.31.31_suppl.34.
Full textAbstract:
34 Background: Research and quality improvement studies often involve an extensive amount of manual review of medical records. The effective management of this process is critical to the consistent, accurate, and cost effective collection and timely dissemination of quality data. Methods: The purpose of this paper is to introduce “OpenQA”, a data management tool designed specifically to help organize, track, and communicate data related to quality improvement studies. OpenQA is designed with ease of chart abstraction, efficiency of data collection, and data transparency as a goal, while providing reporting that support a range of activities related to data management tasks common to hospital quality management departments. The basic method behind OpenQA is to: (1) Provide a centralized online repository for measure related metadata; (2) automatically identify retrospective and prospective encounters that meet specified study inclusion/exclusion criteria; (3) extract key details from structured and unstructured data sources and then combine them to help quality auditors make compliance decisions; (4) provide a workflow engine that supports work lists, alerting and a feedback mechanism for metric stakeholders; (5) provide audit tracking to enable measurability of data collection efforts. Results: Favorable effects were realized post implementation across all measures of performance despite an increase in case volume. Results indicate a decrease in median audit turnaround time, defined as the time between the patient encounter and a decision is made by the auditor, by 23 days (85%). Results also indicate a decrease in the audit reporting turnaround time, defined as the time between the patient encounter and the compliance decision is made and reported. Both reductions were significant at a p value of < 0.05. Conclusions: We suggest that a tool designed to help streamline and standardize the quality improvement data collection process may offer the advantage of minimizing the resource utilization associated with data collection while improving data integrity and shortening the feedback loop.
39
Mustonen, Tero, and Noora Huusari. "How to know about waters? Finnish traditional knowledge related to waters and implications for management reforms." Reviews in Fish Biology and Fisheries 30, no. 4 (September 16, 2020): 699–718. http://dx.doi.org/10.1007/s11160-020-09619-7.
Full textAbstract:
Abstract Finnish lakes, rivers, the Baltic and wetlands–our aquatic ecosystems–are surveyed, assessed and studied using natural sciences and ecological data. We argue that this approach is leaving out a key repository of information–the traditional knowledge of waters. By reviewing aspects, qualities and depth of knowledge across Finland from mid-boreal ecosystems in Eastern Finland to large Saimaa lake system to Western Finnish lakes we demonstrate a potentially reformative approach to aquatic assessments. Cultural indicators, baseline data from oral histories, linguistic diversity and behaviour of species on lakes based on traditional knowledge observations have the potential to greatly enhance our understanding of ecosystem health. Of special importance are the spawning locations of fish known through traditional knowledge, but often ignored by science-based assessments.
40
Liu, Xinrong, Xin Yang, and Junbao Wang. "A Nonlinear Creep Model of Rock Salt and Its Numerical Implement in FLAC3D." Advances in Materials Science and Engineering 2015 (2015): 1–8. http://dx.doi.org/10.1155/2015/285158.
Full textAbstract:
Creep characteristics are integral mechanical properties of rock salt and are related to both long-term stability and security of rock salt repository. Rock salt creep properties are studied in this paper through employing combined methods of theoretical analysis and numerical simulation with a nonlinear creep model and the secondary development in FLAC3Dsoftware. A numerical simulation of multistage loading creep was developed with the model and resulting calculations were found consequently to coincide with previously tested data.
41
Anders, Kristina Ju. "History of the Earliest Russian Old Testament Translation." Slovene 5, no. 1 (2016): 203–17. http://dx.doi.org/10.31168/2305-6754.2016.5.1.7.
Full textAbstract:
This paper introduces a previously unstudied manuscript, “Opyt perevoda vetkhozavetnykh knig [. . .] Mikhailom Fotinskim” (1806). In this article, we analyze the history of this manuscript, the circumstances surrounding the translation, and its purpose; some personal facts about the translator are also reviewed. This source represents the earliest Russian translation of the Old Testament, antedating by more than fifteen years the Russian Bible Society translations. Rev. Mikhail Fotinsky’s translation of five Old Testament books (only two ones in the Genesis) was sent to the Moscow Religious Censorship Committee (Moskovskaia Dukhovnaia tsenzura) in 1806, and the next year, Fotinsky asked the Censorship Committee to allow him to make a translation of the entire Old Testament. However, the censors left the manuscript in their repository, and there was no further development on this project. Contemporaries ignored this translation for several reasons. The first reason might be related to language: Fotinsky’s translation includes many Ukrainian elements. The second reason relates to its literary quality (or lack thereof), as the translation was interlinear and thus not stylistically developed. The manuscript contains many commentaries by Fotinsky, who concentrated on the Hebrew original and Judaic exegesis, trying to show different interpretations that may have occurred as a result of the polysemy of the original text.
42
GIACOMINO, SEBASTIÁN, and JAVIER H. SIGNORELLI. "Systematic redescription of Solen (Ensisolen) tehuelchus and Ensis macha (Bivalvia: Solenoidea) from Argentina, southwestern Atlantic Ocean." Zootaxa 4964, no. 3 (April 23, 2021): 541–58. http://dx.doi.org/10.11646/zootaxa.4964.3.6.
Full textAbstract:
In the present study, bivalves belonging to the superfamily Solenoidea that inhabit the Argentinean Sea are redescribed. The specimens studied in this work were collected by scuba diving in the Gulf of San José, Argentina. Additional specimens from different malacological collections were revised to update the geographical distribution of valid species. According to the literature, there exist two species for the “Argentinean” and “Magellan” biogeographical provinces. However, ten nominal taxa, with uncertain taxonomic status, have been mentioned for the study area. Field work, local collection survey and type material examination allow confirming two valid species: Solen (Ensisolen) tehuelchus Hanley (Solenidae) and Ensis macha (Molina) (Pharidae). A morphological comparison between S. tehuelchus and S. gaudichaudi Chenu and S. obliqua Spengler is provided as well type locality, repository and synonymy list. The type material of all related species are illustrated whenever possible. Establishing the valid names of these species is the first step towards more integrative studies including genetic and zoogeographical analyses.
43
Wilson, Scott. "Community-Driven Specifications." International Journal of IT Standards and Standardization Research 8, no. 2 (July 2010): 74–86. http://dx.doi.org/10.4018/jitsr.2010070106.
Full textAbstract:
This paper explores the issues and opportunities for specifications that develop outside of the traditional governance processes of industry consortia or formal standards organisations through a discussion and comparison of three specifications developed in the education sector: XCRI (eXchanging Course-Related Information), SWORD (Simple Web service Offering Repository Deposit), and LEAP2.0 (Learner Portfolios 2.0). In each case study, there are challenges, opportunities, and accomplishments, and the experiences of each project are compared to identify commonalities and differences. Based on these case studies, the paper applies the framework developed by Wilson and Velayutham (2009) to position the specifications against similar specifications from established consortia and formal standards. Finally, the topic of incubating specifications is discussed, with implications for funding agencies with an interest in supporting interoperability.
44
Kaufman, Jessica, Rebecca Ryan, Cornelia Betsch, Anne Parkhill, Gilla Shapiro, Julie Leask, Lisa Menning, et al. "Instruments that measure psychosocial factors related to vaccination: a scoping review protocol." BMJ Open 9, no. 12 (December 2019): e033938. http://dx.doi.org/10.1136/bmjopen-2019-033938.
Full textAbstract:
IntroductionAs vaccine-preventable disease outbreaks increase, there is growing international interest in monitoring public attitudes towards vaccination and implementing and evaluating vaccine promotion interventions. Outcome selection and measurement are central to intervention evaluation. Measuring uptake rates alone cannot determine which elements in a multicomponent vaccine-promotion intervention are most effective, why specific populations are undervaccinated or when confidence in vaccines is wavering. To develop targeted and cost-effective interventions and policies, it is necessary to measure vaccination-related psychosocial factors such as knowledge, attitudes and aspects of decision-making. This scoping review aims to identify, compare and summarise the properties and validation of instruments for measuring vaccination-related psychosocial factors and identify gaps where no instruments exist.Methods and analysisWe will search Medline OVID, Embase OVID, CINAHL and PsycINFO with no date restriction, using a pilot-tested search strategy of terms related to vaccination: knowledge, attitudes, trust, acceptance and decision-making and measurement, psychometric testing or validation. This search will be supplemented with manual search and expert consultation. We will include studies that describe instrument development, adaptation or testing and include evaluation of at least two measurement properties (eg, content, criterion, or construct validity; test–retest reliability; internal consistency; sensitivity; responsiveness). Instruments measuring a vaccination-related psychosocial factor in any population will be included. All studies will be screened by one reviewer, with a sample double-screened to confirm accuracy. Disagreements will be resolved with a third reviewer. Data will be synthesised narratively and through summary tables to chart and compare instrument characteristics such as factors measured, date and/or location of development or validation, measurement properties evaluated and population.Ethics and disseminationThis scoping review aims to provide an overview of existing instruments and ascertain measurement gaps where no measurement instruments currently exist. The identified instruments will form the basis of an open-access online repository of instruments.
45
Mehranfard, Danial, Gabriela Perez, Andres Rodriguez, Julia M. Ladna, Christopher T. Neagra, Benjamin Goldstein, Timothy Carroll, Alice Tran, Malav Trivedi, and Robert C. Speth. "Alterations in Gene Expression of Renin-Angiotensin System Components and Related Proteins in Colorectal Cancer." Journal of the Renin-Angiotensin-Aldosterone System 2021 (July 5, 2021): 1–17. http://dx.doi.org/10.1155/2021/9987115.
Full textAbstract:
Hypothesis/Introduction. Recent studies suggest involvement of the renin-angiotensin system (RAS) in cancers, including colorectal cancer (CRC). This study focuses on the association of genes encoding 17 proteins related to the RAS within a Japanese male CRC population. Materials and Methods. Quantitative expression of the RNA of these 17 genes in normal and cancerous tissues obtained using chip arrays from the public functional genomics data repository, Gene Expression Omnibus (GEO) application, was compared statistically. Results. Expression of four genes, AGT (angiotensinogen), ENPEP (aminopeptidase A) MME (neprilysin), and PREP (prolyl endopeptidase), was significantly upregulated in CRC specimens. Expression of REN (renin), THOP (thimet oligopeptidase), NLN (neurolysin), PRCP (prolyl carboxypeptidase), ANPEP (aminopeptidase N), and MAS1 (Mas receptor) was downregulated in CRC specimens. Conclusions. Presuming gene expression parallel protein expression, these results suggest that increased production of the angiotensinogen precursor of angiotensin (ANG) peptides, with the reduction of the enzymes that metabolize it to ANG II, can lead to accumulation of angiotensinogen in CRC tissues. Downregulation of THOP, NLN, PRCP, and MAS1 gene expression, whose proteins contribute to the ACE2/ANG 1-7/Mas axis, suggests that reduced activity of this RAS branch could be permissive for oncogenicity. Components of the RAS may be potential therapeutic targets for treatment of CRC.
46
Lee, Colin I. S. G., Frank A. Bosco, Piers Steel, and Krista L. Uggerslev. "A metaBUS-enabled meta-analysis of career satisfaction." Career Development International 22, no. 5 (September 11, 2017): 565–82. http://dx.doi.org/10.1108/cdi-08-2017-0137.
Full textAbstract:
Purpose In this study, the authors revisit the meta-analytic correlates of career satisfaction and demonstrate the use of metaBUS – a database repository of meta-analytic effect sizes and related information from the field of applied psychology. The purpose of this paper is to extend prior meta-analytic research on the topic of career satisfaction and compare the results from the metaBUS-enabled meta-analysis, with the results from meta-analyses that do not build on the repository. Design/methodology/approach A multilevel meta-analysis was conducted on all correlates available in the metaBUS database and the approach was described in a step-by-step fashion. Findings The demonstration reiterated some of the findings of prior meta-analyses, but also revealed considerable incongruity between the sample taken from the metaBUS database and the meta-analytic sample from studies that relied on non-metaBUS-based literature searches. Nevertheless, the results are similar in terms of the directions of the effects and the relative sizes of the effects. Research limitations/implications The paper demonstrates the use of the metaBUS database. In addition, results suggest that meta-analyses on career satisfaction might have suffered from sample selection issues, but further research is required in order to establish the source of the sample selection incongruence. Originality/value This is the first step-by-step demonstration of the use of metaBUS specifically for meta-analyses.
47
Susanto, Susanto, M. Agus Syamsul Arifin, Deris Stiawan, Mohd Yazid Idris, and Rahmat Budiarto. "The trend malware source of IoT network." Indonesian Journal of Electrical Engineering and Computer Science 22, no. 1 (April 1, 2021): 450. http://dx.doi.org/10.11591/ijeecs.v22.i1.pp450-459.
Full textAbstract:
<span>Malware may disrupt the internet of thing (IoT) system/network when it resides in the network, or even harm the network operation. Therefore, malware detection in the IoT system/network becomes an important issue. Research works related to the development of IoT malware detection have been carried out with various methods and algorithms to increase detection accuracy. The majority of papers on malware literature studies discuss mobile networks, and very few consider malware on IoT networks. This paper attempts to identify problems and issues in IoT malware detection presents an analysis of each step in the malware detection as well as provides alternative taxonomy of literature related to IoT malware detection. The focuses of the discussions include malware repository dataset, feature extraction methods, the detection method itself, and the output of each conducted research. Furthermore, a comparison of malware classification approaches accuracy used by researchers in detecting malware in IoT is presented.</span>
48
Sousa, Chriscia Jamilly Pinto, Ana Cristina Lo Prete, Amanda Gabriele Piedade Gomes, Eline Fernandes Ribeiro de Castro, and Carolina Heitmann Mares Azevedo Ribeiro. "Adverse drug events in hospitalized patients in Brazil: Integrative literature review." Research, Society and Development 10, no. 4 (March 29, 2021): e3410413818. http://dx.doi.org/10.33448/rsd-v10i4.13818.
Full textAbstract:
Objective: Analyzing studies related to Adverse Drug Events (ADE) in hospitalized patients in Brazil. Method: integrative review, for which the National Library of Medicine (PubMed), Biblioteca Virtual de Saúde (BVS), Repository of the Fundação Oswaldo Cruz (FIOCRUZ) and Capes Journals databases were selected for searching the studies primary, with the descriptors: Patient Safety, Drug-related side effects and adverse reactions, Patient harm, Hospitalization, Inpatients. Results: Twenty articles were identified, 50% (10) were from the southeast region of Brazil. Regarding the methodology adopted to identify the ADEs, 70% (14) used the retrospective data review. The trackers were used in 5 (25%) articles, 3 of which used the triggers proposed by the Institute for Healthcare Improvement, and the other 2 the trackers used were proposed by the researchers themselves. The number of adverse drug reactions ranged from 12 to 96, while the occurrence of AE ranged from 4 to 122. In one study 50% (41) of participants had at least one adverse drug event. Conclusion: There is great variability in scientific production in Brazil, and in the occurrence of Adverse Drug Events as well. There is a need for strategies to identify these events and create strategies to promote patient safety.
49
Kick, Verena R. "From Photobook to Digital Book: Curating Weimar Germany’s New Visual Literacy Online." Seminar: A Journal of Germanic Studies 57, no. 3 (August 1, 2021): 243–63. http://dx.doi.org/10.3138/seminar.57.3.3.
Full textAbstract:
This contribution focuses on the digital curation of Weimar Germany’s new visual literacy, using Kurt Tucholsky and John Heartfield’s photobook Deutschland, Deutschland über Alles as a case study to examine in which ways a photobook and accompanying research can be showcased online. Tucholsky and Heartfield’s work is an example of the photobook genre that rose to prominence in the 1920s, also for its potential to serve as an “Übungsatlas” (Walter Benjamin) for the new visual literacy. In curating the photobook online, using the publishing platform Scalar and the media repository Critical Commons, the photobook and the accompanying research not only become easily accessible to fellow researchers, students, and the public, but it also becomes possible to emulate and thus explore Weimar Germany’s new visual literacy online. Curating Tucholsky and Heartfield’s photobook and the related analysis online allows for a reflection on digital curation as scholarship, its use in the classroom, and its implications for the trajectory of photobook research.
50
Xing, Danilla, Aleksandra Zecevic, Nicolette Lappan, and Yu Ming. "Fall-Related Injury in Older Adult Home Care Recipients: A Descriptive Population Study." Innovation in Aging 5, Supplement_1 (December 1, 2021): 785–86. http://dx.doi.org/10.1093/geroni/igab046.2900.
Full textAbstract:
Abstract Canada is experiencing a growing aging population leading to an increase in the number of individuals receiving home care. More needs to be known about home care clients who experience fall-related injuries. The purpose of this study was to describe the characteristics of Ontario home care recipients (65 and older) who experienced fall-related injury, and the characteristics of those injuries. We conducted a population-based descriptive study using secondary data from the IC/ES data repository for the period of 2010-2014. Person-level characteristics were extracted from the Resident Assessment Instrument - Home Care and injury characteristics from ICD-10 CA codes for falls (W00-W19) in combination with injuries (S00-S99 or T00-T14), available from the NACRS database. Descriptive statistics and rates were calculated using R. Results show the population (N= 88,731) was primarily female (67.0%), the largest age group was 85-89 years old (25.5%) and hypertension was the most prevalent (83.0%) chronic condition. Clinical Assessment Protocols (CAPs) indicated need for support in management of IADLs (75.4%), falls (72.3%) and pain (70.3%). Most patients (55.8%) used nine or more medications. In 90 days prior to home care assessment, 39.6% experienced no falls, 32.4% fell once, and 26.1% fell two or more times. Injuries primarily took place within the home (38.2%). Factures were the predominant injury type (40.8%), followed by superficial injuries (19.7%). These findings create a foundation for fall-related injury prevention in home care and further research on risk identification, the efficacy of CAPs, and home environment adjustments.