Journal articles on the topic 'Release'
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1
TURNER, SUSAN, and JOAN PETERSILIA. "Work Release in Washington: Effects on Recidivism and Corrections Costs." Prison Journal 76, no. 2 (June 1996): 138–64. http://dx.doi.org/10.1177/0032855596076002003.
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This article presents results from two studies of Washington State's prison work release program conducted between 1991 and 1994. The first study analyzed a cohort of all male prisoners released from Washington prisons in 1990 (N = 2,452) to describe how work release operates and how successfully inmates perform in the program. The second study compared the recidivism of 218 offenders, approximately half of whom participated in work release and half of whom completed their sentences in prison. Results of the evaluation were mostly positive. Nearly a quarter of all prisoners released made a successful transition to the community through work release. Few work release inmates committed crimes while on work release. Recidivism and correctional costs for work releases and nonwork releases were similar.
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Marina, Carlos F., Pablo Liedo, J. Guillermo Bond, Adriana R. Osorio, Javier Valle, Roberto Angulo-Kladt, Yeudiel Gómez-Simuta, Ildefonso Fernández-Salas, Ariane Dor, and Trevor Williams. "Comparison of Ground Release and Drone-Mediated Aerial Release of Aedes aegypti Sterile Males in Southern Mexico: Efficacy and Challenges." Insects 13, no. 4 (March 31, 2022): 347. http://dx.doi.org/10.3390/insects13040347.
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Sterile males of Aedes aegypti were released once a week for 8 weeks to evaluate the dispersal efficiency of ground and aerial drone release methods in a rural village of 26 Ha in southern Mexico. Indoor and outdoor BG-Sentinel traps were placed in 13–16 houses distributed throughout the village. The BG traps were activated 48 h after the release of the sterile males and functioned for a 24 h period following each release. Over the 8-week period of simultaneous ground and aerial releases, an average of 85,117 ± 6457 sterile males/week were released at ground level and 86,724 ± 6474 sterile males/week were released using an aerial drone. The ground release method resulted in higher numbers of captured males (mean = 5.1 ± 1.4, range 1.1–15.7 sterile males/trap) compared with the aerial release method (mean = 2.6 ± 0.8, range 0.5–7.3 sterile males/trap) (p < 0.05). Similarly, the prevalence of traps that captured at least one sterile male was significantly higher for ground release compared to the aerial release method (p < 0.01). The lower numbers of sterile males captured in the aerial release method could be due to mortality or physical injury caused by the chilling process for immobilization, or the compaction of these insects during transport and release. However, aerial releases by a two-person team distributed insects over the entire village in just 20 min, compared to ~90 min of work for a five-person team during the ground release method. Ground release also resulted in higher aggregations of males and some villagers reported feeling discomfort from the presence of large numbers of mosquitoes in and around their houses. We conclude that modifications to the handling and transport of sterile males and the design of containers used to store males are required to avoid injury and to improve the efficiency of aerial releases for area-wide SIT-based population suppression programs targeted at mosquito vectors of human disease.
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Xia, Siyang, Jonah Ury, and Jeffrey R. Powell. "Increasing Effectiveness of Genetically Modifying Mosquito Populations: Risk Assessment of Releasing Blood-Fed Females." American Journal of Tropical Medicine and Hygiene 104, no. 5 (May 5, 2021): 1895–906. http://dx.doi.org/10.4269/ajtmh.19-0729.
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ABSTRACTReleasing mosquito refractory to pathogens has been proposed as a means of controlling mosquito-borne diseases. A recent modeling study demonstrated that instead of the conventional male-only releases, adding blood-fed females to the release population could significantly increase the program’s efficiency, hastening the decrease in disease transmission competence of the target mosquito population and reducing the duration and costs of the release program. However, releasing female mosquitoes presents a short-term risk of increased disease transmission. To quantify this risk, we constructed a Ross–MacDonald model and an individual-based stochastic model to estimate the increase in disease transmission contributed by the released blood-fed females, using the mosquito Aedes aegypti and the dengue virus as a model system. Under baseline parameter values informed by empirical data, our stochastic models predicted a 1.1–5.5% increase in dengue transmission during the initial release, depending on the resistance level of released mosquitoes and release size. The basic reproductive number (R0) increased by 0.45–3.62%. The stochastic simulations were then extended to 10 releases to evaluate the long-term effect. The overall reduction of disease transmission was much greater than the number of potential infections directly contributed by the released females. Releasing blood-fed females with males could also outperform conventional male-only releases when the release strain is sufficiently resistant, and the release size is relatively small. Overall, these results suggested that the long-term benefit of releasing blood-fed females often outweighs the short-term risk.
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Evans, P. D., V. Reale, R. M. Merzon, and J. Villegas. "A comparison of the release of a vasoactive-intestinal-peptide-like peptide and acetylcholine in the giant axon-Schwann cell preparation of the tropical squid Sepioteuthis sepioidea." Journal of Experimental Biology 202, no. 4 (February 15, 1999): 417–28. http://dx.doi.org/10.1242/jeb.202.4.417.
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A vasoactive intestinal peptide (VIP)-like peptide is released by axonal stimulation in the giant axon-Schwann cell preparation from the tropical squid Sepioteuthis sepioidea. It is also released by direct application of l-glutamate, the giant axon-Schwann cell signalling molecule in this preparation. The release of the peptide parallels the release of acetylcholine from the Schwann cells themselves in this preparation in a number of different ways. The release of both acetylcholine and the VIP-like peptide have the same threshold (between 2×10(−10) and 5×10(−10)mol l-1) for l-glutamate application and the same recovery time after inhibition of release by exposure of the preparation to a prolonged pulse of l-glutamate. A prolonged l-glutamate pulse of 10(−8)mol l-1 releases both substances for as long as the pulse is applied to the preparation, whereas a prolonged pulse of 10(−9)mol l-1 l-glutamate releases acetylcholine in the same way but releases the VIP-like peptide only transiently. The VIP-like peptide is likely to be co-released with acetylcholine from the Schwann cells.
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Baston, G. M. N., T. A. Marshall, R. L. Otlet, A. J. Walker, I. D. Mather, and S. J. Williams. "Rate and speciation of volatile carbon-14 and tritium releases from irradiated graphite." Mineralogical Magazine 76, no. 8 (December 2012): 3293–302. http://dx.doi.org/10.1180/minmag.2012.076.8.42.
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AbstractThe release and migration of gaseous carbon-14 has been identified as a key issue for geological disposal of intermediate-level radioactive wastes in the UK. A significant fraction of carbon-14 in the UK inventory is in irradiated graphite. This paper describes measurements of gaseous carbon-14 releases from irradiated graphite on immersion in alkaline solution. Apparatus has been developed to discriminate organic and inorganic (14CO/14CO2) species in the gas phase by means of selective oxidation and capture. In the initial experiment, small amounts of gaseous carbon-14 (∼4 Bq) were released from 9 g of crushed graphite within a two-week period. In a long-term experiment, cumulative releases were measured periodically from an intact specimen of graphite over a 14 month period. A small fraction of the graphite carbon-14 inventory was released to the gas phase (∼0.004% as CO/CO2 and ∼0.001% associated with organic compounds). A larger quantity of carbon-14, about 0.1%, was released to the solution phase and was thought to be mainly 14CO2, with some possible organic component. In general, the rate of gaseous carbon-14 release decreased with time. The results suggest a small initial release of relatively labile, accessible carbon-14, with longer term release occurring at a much slower rate. Tritium (T) releases were also measured.
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Batson, William G., Iain J. Gordon, Donald B. Fletcher, and Adrian D. Manning. "The effect of pre-release captivity on post-release performance in reintroduced eastern bettongs Bettongia gaimardi." Oryx 50, no. 4 (August 11, 2015): 664–73. http://dx.doi.org/10.1017/s0030605315000496.
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AbstractReintroductions are used to re-establish populations of species within their indigenous range, but their outcomes are variable. A key decision when developing a reintroduction strategy is whether to include a temporary period of confinement prior to release. Pre-release confinement is primarily used for the purpose of quarantine or as a delayed-release tactic to influence the performance or behaviour of founders post-release. A common difference between these approaches is that quarantine tends to be conducted in ex situ captivity, whereas delayed releases tend to involve in situ confinement at the release site. Although these practices are commonly viewed independently, it may be possible for a single confinement period to be used for both purposes. We tested whether temporarily holding wild eastern bettongs Bettongia gaimardi in ex situ captivity for 95–345 days prior to release (delayed release) influenced their body mass, pouch occupancy or survival during the first 1.5 years post-release, compared to founders released without confinement (immediate release). Our results suggest that exposing founders to captivity did not alter their body mass or performance post-release, despite being heavier and having fewer pouch young when released. We conclude that, for this species, ex situ captivity does not represent a tactical opportunity to improve post-release performance but can be used for quarantine without affecting the probability of establishment.
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de Visser-Týnová, Eva, Stephen W. Swanton, Stephen J. Williams, Marcel P. Stijkel, Alison J. Walker, and Robert L. Otlet. "14C release from irradiated stainless steel." Radiocarbon 60, no. 6 (November 22, 2018): 1671–81. http://dx.doi.org/10.1017/rdc.2018.134.
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ABSTRACTRadiocarbon (14C or carbon-14, half-life 5730 yr) is a key radionuclide in the assessment of the safety of a geological disposal facility (GDF) for radioactive waste. In particular, the radiological impact of gaseous carbon-14 bearing species has been recognized as a potential issue. Irradiated steels are one of the main sources of carbon-14 in the United Kingdom’s radioactive waste inventory. However, there is considerable uncertainty about the chemical form(s) in which the carbon-14 will be released. The objective of the work was to measure the rate and speciation of carbon-14 release from irradiated 316L(N) stainless steel on leaching under high-pH anoxic conditions, representative of a cement-based near field for low-heat generating wastes. Periodic measurements of carbon-14 releases to both the gas phase and to solution were made in duplicate experiments over a period of up to 417 days. An initial fast release of carbon-14 from the surface of the steel is observed during the first week of leaching, followed by a drop in the rate of release at longer times. Carbon-14 is released primarily to the solution phase with differing fractions released to the gas phase in the two experiments: about 1% of the total release in one and 6% in the other. The predominant dissolved carbon-14 releases are in inorganic form (as 14C-carbonate) but also include organic species. The predominant gas-phase species are hydrocarbons with a smaller fraction of 14CO (which may include some volatile oxygen-containing carbon-species). The experiments are continuing, with final sampling and termination planned after leaching for a total of two years.
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Hoddle, M. S., R. G. Van Driesche, J. P. Sanderson, and O. P. J. M. Minkenberg. "Biological control of Bemisia argentifolii (Hemiptera: Aleyrodidae) on poinsettia with inundative releases of Eretmocerus eremicus (Hymenoptera: Aphelinidae): do release rates affect parasitism?" Bulletin of Entomological Research 88, no. 1 (February 1998): 47–58. http://dx.doi.org/10.1017/s0007485300041547.
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AbstractThe effectiveness of inundative releases of the parasitoid Eretmocerus eremicus n. sp. Rose & Zolnerowich for control of Bemisia argentifolii Bellows & Perring on poinsettia in replicated experimental greenhouses was determined. We evaluated two release rates of E. eremicus: a low release rate (one female per plant per week, released in two greenhouses, in spring 1995) and a high release rate (three females per plant per week, released in two greenhouses, in spring 1994), each over a 14 week growing season. Each release trial had either one (1995) or two (1994) control greenhouses in which B. argentifolii developed on poinsettia in the absence of E. eremicus. Life-tables were constructed for B. argentifolii in the presence and absence of E. eremicus by using a photographic technique to follow cohorts of whiteflies on poinsettia leaves. Weekly population counts of whiteflies were also made. In the absence of E. eremicus, egg to adult survivorship of B. argentifolii on poinsettia was 75–81%. At the low release rate, egg to adult survivorship of B. argentifolii was 12% and parasitism was 34%. At the high release rate, egg to adult survivorship of B. argentifolii was 0.9% and parasitism was 10%. The average net reproductive rates (Ro) for populations of B. argentifolii in the absence of E. eremicus ranged from 20.5 to 26.1, indicating a rapidly increasing population density. Net reproductive rates for whitefly populations subject to parasitoid releases were 3.7 in the low release rate greenhouses, and 0.25 in the high release rate greenhouses, indicating substantially reduced B. argentifolii population growth. At week 14 of the trial, densities of immature whiteflies were lower in greenhouses at the low release rate when compared to the high release rate greenhouses. This was attributed to high levels of in-house reproduction by parasitoids at the low release rate.
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Yamaguchi, Masaaki, Noboru Matsuzaki, Kenji Hirota, Akira Miyake, and Osamu Tanizawa. "Interleukin 6 possibly induced by interleukin 1β in the pituitary gland stimulates the release of gonadotropins and prolactin." Acta Endocrinologica 122, no. 2 (February 1990): 201–5. http://dx.doi.org/10.1530/acta.0.1220201.
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Abstract The abilities of recombinant human interleukin 1 (IL-1) and IL-6 to induce release of FSH, LH and PRL from rat pituitary cells in vitro were examined. IL-1 and IL-6 induced significant releases of FSH, LH and PRL within 3 h. The extents of release of these compounds induced by IL-1 and IL-6 were similar to those induced by GnRH and TRH. Rat anterior pituitary cells released IL-6 spontaneously, and its release was enhanced by IL-1β. This effect of IL-1β was inhibited significantly by a rabbit anti-IL-1β antiserum. These findings suggest that IL-1 induced the release of IL-6 from rat pituitary, and that the released IL-6 stimulated the secretions of FSH, LH and PRL.
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Broschat, Timothy K. "Release Rates of Controlled-Release and Soluble Magnesium Fertilizers." HortTechnology 7, no. 1 (January 1997): 58–60. http://dx.doi.org/10.21273/horttech.7.1.58.
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Release rates at 21 °C were determined in sand columns for 12 commercially available soluble and controlled-release Mg fertilizers. Lutz Mg spikes, K2SO4, MgSO4, MgSO4·H2O, and MgSO4·7H2O released their Mg within 2 to 3 weeks. Within the first 6 weeks, MgO·MgSO4 released its soluble Mg fraction, but little release occurred thereafter. Dolomite and MgO released <5% of their Mg over 2 years while MagAmp released <20% of its Mg. Florikan 1N-0P-26K-4Mg types 100 and 180 exhibited typical controlled-release fertilizer characteristics, with most of their Mg release occurring during the first 15 weeks.
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Taggart, D. A., D. J. Schultz, T. C. Corrigan, T. J. Schultz, M. Stevens, D. Panther, and C. R. White. "Reintroduction methods and a review of mortality in the brush-tailed rock-wallaby, Grampians National Park, Australia." Australian Journal of Zoology 63, no. 6 (2015): 383. http://dx.doi.org/10.1071/zo15029.
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Captive-bred brush-tailed rock-wallabies (BTRW) were reintroduced into the Grampians National Park, Australia, during 2008–12. Two release strategies (methods) were examined: ‘Small release with supplementation’ (Strategy 1) and ‘Larger release, no supplementation’ (Strategy 2). Of the 39 animals released, 18% survived. Thirty-six percent of all mortality occurred within the first 100 days. Under Strategy 1, 22 animals were released in five groups. Twenty deaths occurred across 48 months, with predation estimated to account for 15% of mortalities. Under Strategy 2, 17 individuals were reintroduced across one month. Twelve deaths occurred in the five months following release, with predation estimated to account for 83.4% of mortalities. Of the independent variables tested for their relationship to survival time after release, release strategy was the only significant predictor of survival time after release with the risk of death 3.2 times greater in Strategy 2. Independent variables tested for their relationship to predation risk indicated that release strategy was also the only significant predictor of predation risk, with the risk of death associated with predation 10.5 times greater in Strategy 2. Data suggested that fox predation was the main factor affecting BTRW establishment. Predation risk declined by 75% during the first six months after release. A significant positive relationship was also found between predation risk and colony supplementation events. We conclude that predation risk at Moora Moora Creek is reduced in releases of fewer animals, that it declines across time and that disturbing BTRW colonies through the introduction of new animals can increase predation risk. We recommend that future reintroductions should employ diverse exotic predator control measures at the landscape scale, time releases to periods of lowest predator activity, and limit colony disturbance to maintain group cohesion and social structure. Furthermore, the preferred method of population establishment should be single, small releases over multiple sites without supplementation. Further testing of the reintroduction biology of this species is urgently required.
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Buntin, G. D., R. D. Hudson, and T. R. Murphy. "Establishment of Rhinocyllus conicus (Coleoptera: Curculionidae) in Georgia for Control of Musk Thistle." Journal of Entomological Science 28, no. 2 (April 1, 1993): 213–17. http://dx.doi.org/10.18474/0749-8004-28.2.213.
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Rhinocyllus conicus Froelich was introduced and successfully established at 21 sites in northern Georgia for biological control of musk thistle, Carduus nutans L. A total of 9,310 adults were released from 1990 through 1992. Releases of reproductively mature adults in the spring were much more successful than summer releases of teneral adults. Progeny were observed in all spring-release sites, and population increases occurred at most sites one and two years after release. Consumption of infested capitula by cattle reduced R. conicus numbers at some sites. After two years, weevils had dispersed up to 0.6 km from the initial release point. Transfer of R. conicus to new sites in Georgia will begin in 1993.
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Sotelo Gallardo, Hugo, Armando J. Contreras Balderas, and Alejandro Espinosa Treviño. "Comparación de dos métodos de liberación del berrendo, Antilocapra americana (Artiodactyla: Antilocapridae) en Coahuila, México." Revista de Biología Tropical 65, no. 3 (June 8, 2017): 1208. http://dx.doi.org/10.15517/rbt.v65i3.29447.
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The reintroduction of missing mammal species in former habitats has recently been of high interest. In Mexico, there have been several attempts to reintroduce Antilocapra since 1967, but until now none of the trials has been successful. Nowadays, different releasing methods have been practiced for mammal species, including soft and hard release ones. The aim of this study was to provide new information, and to evaluate the success of a recent release. The study was based on the monitoring of 100 individuals (70 females, 30 males) captured in New Mexico, USA, to be released in Maderas del Carmen, Coahuila, Mexico, in two different groups. The first group (fast release) of 45 specimens (20 females, 25 males) was released in the valley at the beginning of March 2009. The second one (soft release), with 55 individuals (50 female, 5 male), was released in March 2010. For both groups, we compared the mortality rate between dispersal and soft-release vs. hard-release methods. Our results showed that the release with adaptation gave highly significant results (χ2= 2, α= 0.05, p= 0.0001)). The comparison of mortality and dispersion among both methods was highly contrasting: with soft-release we obtained 4 % and 13 % of success, against 23 % and 46 %, respectively. Considering these results, we recommend the soft-release method to be used in future reintroduction attempts of Antilocapra, since more than 50 % of specimens from hard-releases died because of capture stress, or were dispersed, and thus reduced the reintroduction success chances.
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Abdurro’uf, Katherine Accetta, Conny Aerts, Víctor Silva Aguirre, Romina Ahumada, Nikhil Ajgaonkar, N. Filiz Ak, et al. "The Seventeenth Data Release of the Sloan Digital Sky Surveys: Complete Release of MaNGA, MaStar, and APOGEE-2 Data." Astrophysical Journal Supplement Series 259, no. 2 (March 16, 2022): 35. http://dx.doi.org/10.3847/1538-4365/ac4414.
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Abstract This paper documents the seventeenth data release (DR17) from the Sloan Digital Sky Surveys; the fifth and final release from the fourth phase (SDSS-IV). DR17 contains the complete release of the Mapping Nearby Galaxies at Apache Point Observatory (MaNGA) survey, which reached its goal of surveying over 10,000 nearby galaxies. The complete release of the MaNGA Stellar Library accompanies this data, providing observations of almost 30,000 stars through the MaNGA instrument during bright time. DR17 also contains the complete release of the Apache Point Observatory Galactic Evolution Experiment 2 survey that publicly releases infrared spectra of over 650,000 stars. The main sample from the Extended Baryon Oscillation Spectroscopic Survey (eBOSS), as well as the subsurvey Time Domain Spectroscopic Survey data were fully released in DR16. New single-fiber optical spectroscopy released in DR17 is from the SPectroscipic IDentification of ERosita Survey subsurvey and the eBOSS-RM program. Along with the primary data sets, DR17 includes 25 new or updated value-added catalogs. This paper concludes the release of SDSS-IV survey data. SDSS continues into its fifth phase with observations already underway for the Milky Way Mapper, Local Volume Mapper, and Black Hole Mapper surveys.
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Morais, Elisangela Gomes Fidelis, Jéssica Silva Oliveira, Manoel Guedes Corrêa Gondim Jr., and Gilberto José Moraes. "Amblyseius largoensis in controlling red palm mite under semi-field conditions." Pesquisa Agropecuária Brasileira 51, no. 5 (May 2016): 671–75. http://dx.doi.org/10.1590/s0100-204x2016000500030.
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Abstract: The objective of this work was to evaluate the efficiency of two Amblyseius largoensis (Acari: Phytoseiidae) populations in controlling Raoiella indica (Acari: Tenuipalpidae). The treatments were: release of A. largoensis from the island of La Réunion; release of A. largoensis from the state of Roraima, Brazil; and a control, without predator release. Initially, 20 predators were released per plant; three other releases were done at a rate of ten adults per plant, at 46, 135, and 156 days after the first release. The population densities were estimated every 20 days, during six months. Both A. largoensis populations evaluated are not sufficiently efficient to control the R. indica population.
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Oja, Simo S., and Pirjo Saransaari. "Ischemia Induces Release of Endogenous Amino Acids from the Cerebral Cortex and Cerebellum of Developing and Adult Mice." Journal of Amino Acids 2013 (January 10, 2013): 1–11. http://dx.doi.org/10.1155/2013/839036.
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Ischemia enhanced release of endogenous neuroactive amino acids from cerebellar and cerebral cortical slices. More glutamate was released in adult than developing mice. Taurine release enhanced by K+ stimulation and ischemia was more than one magnitude greater than that of GABA or glutamate in the developing cerebral cortex and cerebellum, while in adults the releases were almost comparable. Aspartate release was prominently enhanced by both ischemia and K+ stimulation in the adult cerebral cortex. In the cerebellum K+ stimulation and ischemia evoked almost 10-fold greater GABA release in 3-month olds than in 7-day olds. The release of taurine increased severalfold in the cerebellum of 7-day-old mice in high-K+ media, whereas the K+-evoked effect was rather small in adults. In 3-month-old mice no effects of K+ stimulation or ischemia were seen in the release of aspartate, glycine, glutamine, alanine, serine, or threonine. The releases from the cerebral cortex and cerebellum were markedly different and also differed between developing and adult mice. In developing mice only the release of inhibitory taurine may be large enough to counteract the harmful effects of excitatory amino acids in ischemia in both cerebral cortex and cerebellum, in particular since at that age the release of glutamate and aspartate cannot be described as massive.
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Bento, J. M. S., G. J. de Moraes, A. C. Bellotti, J. A. Castillo, J. F. Warumby, and S. L. Lapointe. "Introduction of parasitoids for the control of the cassava mealybug Phenacoccus herreni (Hemiptera: Pseudococcidae) in north-eastern Brazil." Bulletin of Entomological Research 89, no. 5 (May 1999): 403–10. http://dx.doi.org/10.1017/s000748539900053x.
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AbstractThe mealybug Phenacoccus herreni Cox & Williams causes considerable damage to cassava Manihot esculenta Crantz. Field surveys conducted between 1988 and 1994 indicated the mealybug was present in 57 municipalities in six States in north-eastern Brazil, in some places reaching high levels of infestation. Several native natural enemy species were found associated with the pest in Brazil. Exotic encyrtid parasitoids were imported and released in fields in the States of Bahia and Pernambuco. Apoanagyrus diversicornis (Howard) was introduced from Colombia, and Acerophagus coccois Smith, and Aenasius vexans (Kerrich) were introduced from Venezuela. By the end of 1996, a total of 35,930 parasitoids had been released. In Bahia, Apoanagyrus diversicornis was recovered 130, 234, 304 and 550 km from its release site after 6, 14, 21 and 33 months, respectively. Acerophagus coccois was recovered at 180 km from its release site nine months after release. Aenasius vexans, however, did not disperse at all despite being consistently recovered at its release site. In Pernambuco, 9010 parasitoids were released from October, 1995 onwards. Acerophagus coccois and Aenasius vexans were recovered up to 40 km from the release sites after three and five months of their initial releases, respectively. The establishment and dispersal of these parasitoids are discussed.
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Prange, Oliver, and Timothy H. Murphy. "Analysis of Multiquantal Transmitter Release From Single Cultured Cortical Neuron Terminals." Journal of Neurophysiology 81, no. 4 (April 1, 1999): 1810–17. http://dx.doi.org/10.1152/jn.1999.81.4.1810.
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Analysis of multiquantal transmitter release from single cultured cortical neuron terminals. Application of single synapse recording methods indicates that the amplitude of postsynaptic responses of single CNS synapses can vary greatly among repeated stimuli. To determine whether this observation could be attributed to synapses releasing a variable number of transmitter quanta, we assessed the prevalence of multiquantal transmitter release in primary cultures of cortical neurons with the action potential (AP)-dependent presynaptic turnover of the styryl dye FM1–43 ( Betz and Bewick 1992 , 1993 ; Betz et al. 1996 ). It was assumed that if a high proportion of vesicles within a terminal were loaded with FM1–43 the amount of dye released per stimulus would be proportional to the number of quanta released and/or the probability of release at a terminal. To rule out differences in the amount of release (between terminals) caused by release probability or incomplete loading of terminals, conditions were chosen to maximize both release probability and terminal loading. Three-dimensional reconstruction of terminals was employed to ensure that bouton fluorescence was accurately measured. Analysis of the relationship between the loading of terminals and release indicated that presumed larger terminals (>FM1–43 uptake) release a greater amount of dye per stimulus than smaller terminals, suggesting multiquantal release. The distribution of release amounts across terminals was significantly skewed toward higher values, with 13–17% of synaptic terminals apparently releasing multiple quanta per AP. In conclusion, our data suggest that most synaptic terminals release a relatively constant amount of transmitter per stimulus; however, a subset of terminals releases amounts of FM1–43 that are greater than that expected from a unimodal release process.
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Broschat, Timothy K. "Release Rates of Soluble and Controlled-release Boron Fertilizers." HortTechnology 18, no. 3 (January 2008): 471–74. http://dx.doi.org/10.21273/horttech.18.3.471.
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The relative release rates of boron (B) from nine soluble and controlled-release B fertilizer sources were determined in sand leaching columns at 21 °C. Solubor was almost completely leached from the sand within 5 weeks. Boric oxide released the majority of its B within 7 weeks, whereas Dehybor provided B for up to 13 weeks. Granubor release rates were linear through ≈12 weeks. The five products containing calcium or sodium calcium borates released B much more slowly, with probertite and ulexite being the most rapid followed by B32 G, colemanite, and B38 G. B38 G released only ≈40% of its B content during the 104-week leaching study. The rapid release and high B concentrations associated with Solubor suggest a greater potential for phytotoxicity with this source than other slower-release sources.
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van Langevelde, Petra, Kitty M. C. Kwappenberg, Paul H. P. Groeneveld, Herman Mattie, and Jaap T. van Dissel. "Antibiotic-Induced Lipopolysaccharide (LPS) Release from Salmonella typhi: Delay between Killing by Ceftazidime and Imipenem and Release of LPS." Antimicrobial Agents and Chemotherapy 42, no. 4 (April 1, 1998): 739–43. http://dx.doi.org/10.1128/aac.42.4.739.
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ABSTRACT It has been suggested that the antibiotic-induced release of lipopolysaccharide (LPS) is an important cause of the development of septic shock in patients treated for severe infections caused by gram-negative bacteria. β-Lactam antibiotics change the integrity of the bacterial cell envelope by binding to penicillin-binding proteins (PBP) in the membrane and thus may affect the amount of LPS that is released and the kinetics of that release. In this respect, ceftazidime at intermediate concentrations binds with a high affinity to PBP 3 and PBP 1a and thus can induce filament formation in addition to killing, whereas imipenem preferentially binds to PBP 2 and PBP 1b, leading to spheroplast formation and rapid cell lysis. We investigated the effects of these antibiotics on the killing and the release of the radioactively labelled LPS of Salmonella typhi Ty 21A. A mathematical model was developed to calculate the delay between bacterial killing and LPS release, designated the lag time. At antibiotic concentrations inducing equal killing, the amount of LPS released was the same for both antibiotics. Only after 6 h of incubation at antibiotic concentrations above 0.5 μg/ml, the amount of 3H-LPS released was slightly higher (∼1.2-fold) in incubations with ceftazidime than in those with imipenem, and the maximum releases of the total label were 33.2% ± 0.89% and 27.1% ± 0.45%, respectively. Despite the clear concentration-dependent effect on the bacterial killing and subsequent LPS release, the lag time was independent of the antibiotic concentration. For ceftazidime as well as imipenem the lag time amounted to approximately 60 min. In conclusion, our findings imply that the mechanism of antibiotic-induced LPS release is independent of the PBP affinities for these β-lactam antibiotics. Furthermore, once the organism is killed by either imipenem or ceftazidime, the rate of LPS release from S. typhi does not differ according to the antibiotic with which the organism is killed, and there is little difference in the relative amount of LPS released.
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Clark, M. G., S. M. Richards, M. Hettiarachchi, J. M. Ye, G. J. Appleby, S. Rattigan, and E. Q. Colquhoun. "Release of purine and pyrimidine nucleosides and their catabolites from the perfused rat hindlimb in response to noradrenaline, vasopressin, angiotensin II and sciatic-nerve stimulation." Biochemical Journal 266, no. 3 (March 15, 1990): 765–70. http://dx.doi.org/10.1042/bj2660765.
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Uric acid and uracil were released at constant rates (0.95 and 0.4 nmol/min per g respectively) by the perfused rat hindlimb. Noradrenaline, vasopressin or angiotensin II further increased the release of these substances 2-5-fold, coinciding with increases in both perfusion pressure (vasoconstriction) and O2 uptake. The hindlimb also released, but in lesser amounts, uridine, hypoxanthine, xanthine, inosine and guanosine, and all but hypoxanthine and guanosine were increased during intense vasoconstriction. Uric acid and uracil releases were increased by noradrenaline in a dose-dependent manner. However, the release of these substances did not fully correspond with the dose-dependent increase in O2 uptake and perfusion pressure, where changes in the latter occurred at lower doses of noradrenaline. Sciatic-nerve stimulation (skeletal-muscle contraction) did not increase the release of uracil, uric acid or uridine, but instead increased the release of inosine (7-fold) and hypoxanthine (2-fold). Since the UTP content as well as the UTP/ATP ratio are higher in smooth muscle than in skeletal muscle, it is proposed that release of uric acid and uracil arises from increased metabolism of the respective adenosine and uridine nucleotides during intense constriction of smooth muscle.
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Hu, Huijian, and Zhigang Jiang. "Trial release of Père David's deer Elaphurus davidianus in the Dafeng Reserve, China." Oryx 36, no. 2 (April 2002): 196–99. http://dx.doi.org/10.1017/s0030605302000273.
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The Critically Endangered Père David's deer Elaphurus davidianu became extinct in the wild in China in about 1900, and the only surviving animals were held in captivity at Woburn Abbey in the UK. During 1985–1987, individuals were returned to China, and subsequent growth of the captive population in enclosures at Dafeng Reserve necessitated a trial release of a small group of deer as a prelude to further releases. Seven individuals were released into the unfenced coastal region of the Dafeng Reserve in 1998. Behaviour, daily activity rhythm, habitat selection, activity range and body condition were recorded for six months after release. The deer exhibited initial changes in behaviour, but returned to their pre-release patterns about four weeks after release, and by six weeks after release their body condition had improved compared to their previous condition in captivity. They left the Reserve and began to forage on farmland, causing conflict with local people. Further releases should be into areas with either a natural or artificial boundary in order to avoid unmanageable levels of conflict between the needs of the deer and those of farmers.
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Nicholson, D., T. D. White, and J. Sawynok. "Forskolin and phosphodiesterase inhibitors release adenosine but inhibit morphine-evoked release of adenosine from spinal cord synaptosomes." Canadian Journal of Physiology and Pharmacology 69, no. 6 (June 1, 1991): 877–85. http://dx.doi.org/10.1139/y91-133.
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The effects of forskolin, Ro 20-1724, rolipram, and 3-isobutyl-1-methylxanthine (IBMX) on morphine-evoked release of adenosine from dorsal spinal cord synaptosomes were evaluated to examine the potential involvement of cyclic AMP in this action of morphine. Ro 20-1724 (1–100 μM), rolipram (1–100 μM), and forskolin (1–10 μM) increased basal release of adenosine, and at 1 μM inhibited morphine-evoked release of adenosine. Release of adenosine by Ro 20-1724, rolipram, and forskolin was reduced 42–77% in the presence of α, β-methylene ADP and GMP, which inhibits ecto-5′-nucleotidase activity by 81%, indicating that this adenosine originated predominantly as nucleotide(s). Significant amounts of adenosine also were released from the ventral spinal cord by these agents. Ro 20-1724 and rolipram did not significantly alter the uptake of adenosine into synaptosomes. Although Ro 20-1724 and rolipram had only limited effects on the extrasynaptosomal conversion of added cyclic AMP to adenosine, IBMX, a phosphodiesterase inhibitor with a broader spectrum of inhibitory activity for phosphodiesterase isoenzymes, significantly inhibited the conversion of cyclic AMP to adenosine and resulted in recovery of a substantial amount of cyclic AMP. As with the non-xanthine phosphodiesterase inhibitors, IBMX increased basal release of adenosine and reduced morphine-evoked release of adenosine. Adenosine released by IBMX was reduced 70% in the presence of α, β-methylene ADP and GMP, and release from the ventral spinal cord was 61% of that from the dorsal spinal cord. Collectively, these results indicate that forskolin and phosphodiesterase inhibitors release nucleotide(s) which is (are) converted extrasynaptosomally to adenosine. For forskolin, Ro 20-1724, and rolipram, the nucleotide released could be cyclic AMP. Morphine releases adenosine per se, and forskolin and phosphodiesterase inhibitors reduce this release. The lack of increase in the action of morphine with phosphodiesterase inhibitors in particular does not support a role for stimulation of cyclic AMP production by morphine in the release of adenosine. The reduction in morphine-evoked release of adenosine by forskolin and phosphodiesterase inhibitors suggests either (a) that a reduction in cyclic levels by morphine promotes adenosine release, or (b) that cyclic AMP interferes with the release process.Key words: forskolin, Ro 20-1724, 3-isobutyl-1-methylxanthine, cyclic AMP, morphine, adenosine release, spinal cord.
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Kothawale, Shraddha, and Keerthi Rao. "EFFECTIVENESS OF POSITIONAL RELEASE TECHNIQUE VERSUS ACTIVE RELEASE TECHNIQUE ON HAMSTRINGS TIGHTNESS." International Journal of Physiotherapy and Research 6, no. 1 (February 11, 2018): 2619–22. http://dx.doi.org/10.16965/ijpr.2017.265.
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Karim, Samira, Mohiuddin Ahmed Bhuiyan, and Md Sohel Rana. "Formulation and in vitro Evaluation of Glimepiride Sustained Release Tablets: Comparison with Immediate Release Tablets." Bangladesh Pharmaceutical Journal 18, no. 2 (July 26, 2015): 157–62. http://dx.doi.org/10.3329/bpj.v18i2.24315.
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This work aims at the design of a sustained release formulation of glimepiride which is currently available in the treatment of type 2 diabetes mellitus and to investigate the effect of polymers on the release profile of glimepiride. Glimepiride sustained release tablets were prepared by direct compression method using different ratios of various release retarding polymers such as carbopol, ethyl cellulose, methocel K4 MCR, methocel K15 MCR, methocel K100 MCR and xanthum gum. These formulations were also compared with glimepiride immediate release tablets. The prepared tablets were subjected to various physical parameter tests including weight variation, friability, hardness, thickness, diameter, etc. In vitro dissolution studies of the formulations were done at pH 6.8 in phosphate buffer using USP apparatus 2 (paddle method) at 50 rpm. The percent releases of all the formulations (30) were 73.11%- 98.76% after 8 hours. The release pattern followed zero order kinetics and the release of the drug was hindered by the polymers used in the study. On the other hand, 100% drug was released within 1 hour from the immediate release tablet of glimepiride. The study reveals that the polymers used have the capacity to retard the release of the drug from the sustained release tablets and the more is the amount of the polymer in the formulation the less is the release of drug showing more retardation of drug release.Bangladesh Pharmaceutical Journal 18(2): 157-162, 2015
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Jamieson, L. E., K. Froud, R. Edwards, and P. S. Stevens. "Establishment of Thripobius javae (semiluteus) in New Zealand." New Zealand Plant Protection 61 (August 1, 2008): 17–23. http://dx.doi.org/10.30843/nzpp.2008.61.6827.
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The larval parasitoid Thripobius javae was imported from Italy into New Zealand in December 2000 as part of a classical biological control programme against greenhouse thrips (Heliothrips haemorrhoidalis) Thripobius javae was released from containment in Auckland in January 2001 Subsequent releases were made in 2001 at sites in Kerikeri Whangarei Bay of Plenty and Gisborne Release sites were monitored for greenhouse thrips and T javae 14 times between 2002 and 2007 Thripobius javae was recovered from 11 of the 21 release sites More intensive monitoring of a citrus orchard in Kerikeri found that 95100 of threetree plots had T javae present 1 year after release After 6 years the parasitoid was found in only 2128 of plots and had dispersed at least 200 m from this release site It has since been found in isolated areas where it was never released Using trap lemons infested with larval greenhouse thrips was not an effective method for detecting T javae Sticky traps did catch some parasitoids and may be a potential method for determining presence/absence
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Brunner, G., CN Metz, H. Nguyen, J. Gabrilove, SR Patel, MA Davitz, DB Rifkin, and EL Wilson. "An endogenous glycosylphosphatidylinositol-specific phospholipase D releases basic fibroblast growth factor-heparan sulfate proteoglycan complexes from human bone marrow cultures." Blood 83, no. 8 (April 15, 1994): 2115–25. http://dx.doi.org/10.1182/blood.v83.8.2115.2115.
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Abstract Basic fibroblast growth factor (bFGF) is a hematopoietic cytokine that stimulates stromal and stem cell growth. It binds to a glycosylphosphatidylinositol (GPI)-anchored heparan sulfate proteoglycan on human bone marrow (BM) stromal cells. The bFGF- proteoglycan complex is biologically active and is released by addition of exogenous phosphatidylinositol-specific phospholipase C. In this study, we show the presence of an endogenous GPI-specific phospholipase D (GPI-PLD) that releases the bFGF-binding heparan sulfate proteoglycan and the variant surface glycoprotein (a model GPI-anchored protein) from BM cultures. An involvement of proteases in this process is unlikely, because released proteoglycan contained the GPI anchor component, ethanol-amine, and protease inhibitors did not diminish the release. The mechanism of release is likely to involve a GPI-PLD and not a GPI-specific phospholipase C, because the release of variant surface glycoprotein did not reveal an epitope called the cross- reacting determinant that is exposed by phospholipase C-catalyzed GPI anchor cleavage. In addition, phosphatidic acid (which is specifically a product of GPI-PLD-catalyzed anchor cleavage) was generated during the spontaneous release of the GPI-anchored variant surface glycoprotein. We also detected GPI-PLD-specific enzyme activity and mRNA in BM cells. Therefore, we conclude that an endogenous GPI-PLD releases bFGF-heparan sulfate proteoglycan complexes from human BM cultures. This mechanism of GPI anchor cleavage could be relevant for mobilizing biologically active bFGF in BM. An endogenous GPI-PLD could also release other GPI-anchored proteins important for hematopoiesis and other physiologic processes.
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Brunner, G., CN Metz, H. Nguyen, J. Gabrilove, SR Patel, MA Davitz, DB Rifkin, and EL Wilson. "An endogenous glycosylphosphatidylinositol-specific phospholipase D releases basic fibroblast growth factor-heparan sulfate proteoglycan complexes from human bone marrow cultures." Blood 83, no. 8 (April 15, 1994): 2115–25. http://dx.doi.org/10.1182/blood.v83.8.2115.bloodjournal8382115.
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Basic fibroblast growth factor (bFGF) is a hematopoietic cytokine that stimulates stromal and stem cell growth. It binds to a glycosylphosphatidylinositol (GPI)-anchored heparan sulfate proteoglycan on human bone marrow (BM) stromal cells. The bFGF- proteoglycan complex is biologically active and is released by addition of exogenous phosphatidylinositol-specific phospholipase C. In this study, we show the presence of an endogenous GPI-specific phospholipase D (GPI-PLD) that releases the bFGF-binding heparan sulfate proteoglycan and the variant surface glycoprotein (a model GPI-anchored protein) from BM cultures. An involvement of proteases in this process is unlikely, because released proteoglycan contained the GPI anchor component, ethanol-amine, and protease inhibitors did not diminish the release. The mechanism of release is likely to involve a GPI-PLD and not a GPI-specific phospholipase C, because the release of variant surface glycoprotein did not reveal an epitope called the cross- reacting determinant that is exposed by phospholipase C-catalyzed GPI anchor cleavage. In addition, phosphatidic acid (which is specifically a product of GPI-PLD-catalyzed anchor cleavage) was generated during the spontaneous release of the GPI-anchored variant surface glycoprotein. We also detected GPI-PLD-specific enzyme activity and mRNA in BM cells. Therefore, we conclude that an endogenous GPI-PLD releases bFGF-heparan sulfate proteoglycan complexes from human BM cultures. This mechanism of GPI anchor cleavage could be relevant for mobilizing biologically active bFGF in BM. An endogenous GPI-PLD could also release other GPI-anchored proteins important for hematopoiesis and other physiologic processes.
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McNeill, M. R., P. J. Addison, J. R. Proffitt, C. B. Phillips, and S. L. Goldson. "Microctonus hyperodae a summary of releases and distribution in New Zealand pasture." New Zealand Plant Protection 55 (August 1, 2002): 272–79. http://dx.doi.org/10.30843/nzpp.2002.55.3952.
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The braconid parasitoid Microctonus hyperodae was released in New Zealand for biological control of Argentine stem weevil Listronotus bonariensis The initial 1991 research introduction involved the release of 99000 parasitised L bonariensis Between 1991 and 1998 a further 660000 M hyperodae were released as part of commercial contracts and research programmes Commercial contracts resulted in the widespread release of the parasitoid in the North Island with South Island releases mainly confined to midCanterbury There were eight geographic populations originally collected from South America and these were maintained separately in the laboratory Excluding the Mendoza population which was founded on a single female an average of 91040 M hyperodae was released from each of the seven remaining populations Parasitised L bonariensis were released at a total of 121 sites and the parasitoid established at 118 (975) Based on the distribution of releases in New Zealand and the results of surveys it is estimated that M hyperodae is now very widely distributed in the North Island with more limited distribution in the South Island
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Smith, S. M., and D. R. Wallace. "3.2 GROUND SYSTEMS FOR RELEASING TRICHOGRAMMA MINUTUM RILEY IN PLANTATION FORESTS." Memoirs of the Entomological Society of Canada 122, S153 (1990): 31–37. http://dx.doi.org/10.4039/entm122153031-1.
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AbstractTwo systems for releasing the egg parasitoid, Trichogramma minutum Riley, from ground level in forest stands are described: (1) a gridded point-source release using parasitized host eggs attached to cards, and (2) a hand-held leafblower distributing parasitized eggs in bulk. Neither technique affected the emergence of the parasitoids released. Parasitoids emerging from eggs released in bulk had a similar sex ratio, longevity, and fecundity to those not released. Both methods of ground release achieved uniform parasitoid distribution and resulted in levels of parasitism similar to those achieved with aerial releases. Parasitism was greater in the mid- to upper canopy of trees than in the lower canopy. The difficulties associated with each technique and its comparative usefulness in experimental and operational programs are discussed.
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Sufarnap, Erliera, Kholidina Imanda Harahap, Ika Devi Adiana, Davin Lim, Chatty Lim, and Christy Christy. "Corrosion of copper nickel titanium archwire in chlorhexidine, sodium fluoride, and chitosan mouthwashes." F1000Research 12 (February 10, 2023): 159. http://dx.doi.org/10.12688/f1000research.129043.1.
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Background: Copper (Cu), nickel (Ni), chromium (Cr) ion release, and surface topography change from the orthodontic wire are the initial processes of corrosion that may affect the mechanical properties of the archwire. In this study, we aim to evaluate the effect of CHX, NaF, and chitosan on the corrosion of CuNiTi wire nickel and copper ions released, surface roughness change, and archwire deflection. Methods: Ninety samples of CuNiTi Tanzo™ archwires were divided into five groups according to their immersion solution: Artificial Saliva, CHX, NaF, CHX-NaF, and chitosan group. Each group was further divided into three subgroups (n=6) corresponding immersion time, i.e., two, four, and six weeks. The corrosion of the samples was analyzed with an atomic absorption spectrophotometer (AAS), scanning electron microscope (SEM), and universal testing machine (UTM). Results: The amount of nickel ion releases was increasing, but the copper ion releases were reduced by the time of observations. The highest nickel ion was released in the CHX-NaF group and the lowest in the chitosan group for six-week immersion. It also corresponded to the surface topography by SEM analysis which showed the most extended cracks and deep pits in the CHX-NaF group and a smoother surface in the chitosan group. Copper ion release showed the highest ion release in the NaF group and the lowest release in the chitosan group. The unloading force of CuNiTi archwire deflection remains the same at week two and week four for all mouthwashes. Conclusion: The use of mouthwashes that contained CHX, NaF, and chitosan could further alter the passive layer and cause higher nickel and copper ion release and increased CuNiTi archwire surface structure porosity. But there is no distinction between mouthwashes to release the unloading force within two until four weeks.
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Martinez, Luis R., Dariush Moussai, and Arturo Casadevall. "Antibody to Cryptococcus neoformans Glucuronoxylomannan Inhibits the Release of Capsular Antigen." Infection and Immunity 72, no. 6 (June 2004): 3674–79. http://dx.doi.org/10.1128/iai.72.6.3674-3679.2004.
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ABSTRACT Cryptococcus neoformans releases capsular polysaccharide in the supernatant of liquid cultures and in tissues. Significantly less glucuronoxylomannan (GXM) was released by C. neoformans in the presence of capsule-binding monoclonal antibody (MAb). MAb-mediated inhibition of GXM release may be another mechanism by which humoral immunity can mediate protection against this pathogen.
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KOCA, Uğur. "Airway Pressure Release Ventilation." Turkiye Klinikleri Journal of Anesthesiology Reanimation 16, no. 1 (2018): 14–17. http://dx.doi.org/10.5336/anesthe.2017-57257.
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Sheppard, M. S., B. A. Eatock, and R. M. Bala. "Characteristics of phorbol ester stimulated growth hormone release: inhibition by insulin-like growth factor I, somatostatin, and low calcium medium and comparison with growth hormone releasing factor." Canadian Journal of Physiology and Pharmacology 65, no. 11 (November 1, 1987): 2302–7. http://dx.doi.org/10.1139/y87-365.
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TPA (12-O-tetradecanoylphorbol 13-acetate) is one of a class of compounds known as tumor promoters which perturb the inositol phosphate pathway in a number of cells. We have used TPA in a dispersed rat adenohypophysial cell system to probe the characteristics of growth hormone (GH) release. In this system we have found that the cells release GH in response to low concentrations of TPA: the EC50 was 0.23 ± 0.05 nM (n = 6) and the maximal concentration was 5 nM. However, the maximal TPA-induced GH release was only 34 ± 5% (n = 7) of the GH released by maximal growth hormone releasing factor (GRF) suggesting TPA releases a subpool of stored GH. Both somatostatin and insulin-like growth factor I inhibit GH release stimulated by TPA to the same extent as that stimulated by GRF, showing that the normal inhibitory control mechanism of release is not altered. Incubation in a low calcium medium that totally blocks GRF-stimuiated GH release also inhibits TPA-stimulated GH release. The calcium channel blockers nifedipine and diltiazem both partly inhibit GRF- and TPA-stimulated GH release, showing some component of the calcium necessary for GH release arises from influx across the cell membrane.
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Palis, Heather, Kevin Hu, William Rioux, Mo Korchinski, Pam Young, Leigh Greiner, Tonia Nicholls, and Amanda Slaunwhite. "Association of Mental Health Services Access and Reincarceration Among Adults Released From Prison in British Columbia, Canada." JAMA Network Open 5, no. 12 (December 15, 2022): e2247146. http://dx.doi.org/10.1001/jamanetworkopen.2022.47146.
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ImportanceDiagnosis of mental disorder is prevalent among people who have been incarcerated. Nevertheless, community mental health services are often limited following release from prison, and reincarceration rates are high. The prevalence of mental disorders is growing among people who are incarcerated in British Columbia (BC), Canada, increasing the urgency of timely and accessible mental health services after release.ObjectiveTo examine the association of mental health services access and timeliness of services access with reincarceration risk among people released from prison.Design, Setting, and ParticipantsIn this cohort study, mental disorder diagnoses were derived from International Classification of Diseases, Ninth Revision or International Statistical Classification of Diseases and Related Health Problems, Tenth Revision codes in administrative health records. Data on prison release and reincarceration were retrieved from corrections records. Population-based health and corrections data were retrieved from the BC Provincial Overdose Cohort, which contains a 20% general population random sample of 1 089 677 BC residents. This study examined releases from provincial prisons between January 1, 2015, and December 31, 2018, among people in the 20% random sample who had a mental disorder diagnosis in the year before their release. Analyses were performed from January to June 2022.ExposuresMental health services access (primary care, emergency department visits, or hospitalization) and sociodemographic, health, and incarceration characteristics.Main Outcomes and MeasuresA multistate modeling approach was taken. Cox proportional hazards models were stratified by transition, from release to reincarceration, with and without mental health services access. A state arrival extended model examined the influence of timeliness of mental health services access on subsequent hazard of reincarceration.ResultsA total of 4171 releases among 1664 people (3565 releases among male individuals [84.6%]; 2948 releases [70.7%] among people &lt;40 years old; 2939 releases [70.5%] among people with concurrent substance use disorder diagnosis) were identified. The total study follow-up time was 2834.53 person-years, with a mean (SD) of 0.68 (0.93) years and median (IQR) of 0.25 (0.07-0.84) years per release. Mental health services access was associated with a reduction in the hazard of reincarceration (hazard ratio, 0.61; 95% CI, 0.39-0.94). For each additional month between release and mental health services access, the hazard of reincarceration was increased by 4% (hazard ratio, 1.04; 95% CI, 1.01-1.07).Conclusions and RelevanceIn this cohort study of people with mental disorder diagnoses released from prison in BC, mental health services access was associated with reduced reincarceration risk. These findings suggest that these services may have the greatest impact on reducing reincarceration risk when they are available in a timely manner in the days and weeks immediately following release.
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Koyama, S., S. I. Rennard, and R. A. Robbins. "Bradykinin stimulates bronchial epithelial cells to release neutrophil and monocyte chemotactic activity." American Journal of Physiology-Lung Cellular and Molecular Physiology 269, no. 1 (July 1, 1995): L38—L44. http://dx.doi.org/10.1152/ajplung.1995.269.1.l38.
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In the present investigation, we evaluated the potential of bradykinin (BK), histamine, and serotonin to induce the release of neutrophil and monocyte chemotactic activity (NCA and MCA) from bronchial epithelial cells (BEC). BK significantly stimulated BEC to release NCA and MCA in a dose- and time-dependent manner. Histamine weakly but significantly induced the release of both NCA and MCA in a similar fashion. Serotonin did not stimulate BEC. Checkerboard analysis showed that the NCA and MCA released in response to BK were chemotactic. Molecular-sieve column chromatography by Sephadex G-75 revealed that BK induced a single low-molecular-weight peak (approximately 400 Da) for both NCA and MCA. The releases of NCA and MCA in response to BK and histamine were inhibited by lipoxygenase inhibitors (P < 0.01). The released NCA was inhibited by leukotriene B4 (LTB4) receptor antagonist (P < 0.01) and was slightly inhibited by platelet-activating factor receptor antagonist. LTB4 was increased in BK-stimulated BEC supernatant (P < 0.01). BK B2-receptor antagonist attenuated the release of NCA and MCA. These data suggest that BK and histamine may stimulate BEC to release NCA and MCA and may modulate neutrophil and monocyte recruitment into the airways in patients with asthma.
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Ritschel, Wolfgang A., and Mukul A. Agrawal. "Physiologically based novel peroral modified release drug delivery system: Self-destructing hydrogel piston-pump." Ciencia e Investigación 6, no. 2 (December 31, 2003): 24–29. http://dx.doi.org/10.15381/ci.v6i2.3439.
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Peroral modified drug delivery systems on the market release fue drug by either 0-order, 1º-order, square root oftime or mixed rate. This means that the drugis released mto the gastrointestinallumenin amounts being either constantper unit of time or decreasingwith time. However, physiologically absorption from the GI lumen gets slower and more difficult past the small intestme. A novel drug delivery system is described far 24 horus drug delivery which follows approximate 0-orden release throughout the small intestine, but releases increasing amounts of drug once in the colon ta compensate for increasingly more difficult absorption. Nearly constant steady state drug plasma concentrations are achieved . The novel drug delivery system is a two layered dosage form with an immediate release layer and a modified release layer. The latter ene is a hydrogel piston pump comprised of a drug core layer and a hydrogel swelling layer, embedded into a semipermeable shell by compression coating. The upper site of the shell has a release channel in the center.
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Geiger, Jeremy, Deborah Wessels, Shawn R. Lockhart, and David R. Soll. "Release of a Potent Polymorphonuclear Leukocyte Chemoattractant Is Regulated by White-Opaque Switching in Candida albicans." Infection and Immunity 72, no. 2 (February 2004): 667–77. http://dx.doi.org/10.1128/iai.72.2.667-677.2004.
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ABSTRACT Previous studies employing transmembrane assays suggested that Candida albicans and related species, as well as Saccharomyces cerevisiae, release chemoattractants for human polymorphonuclear leukocytes (PMNs). Because transmembrane assays do not definitively distinguish between chemokinesis and chemotaxis, single-cell chemotaxis assays were used to confirm these findings and test whether mating-type or white-opaque switching affects the release of attractant. Our results demonstrate that C. albicans, C. dubliniensis, C. tropicalis, C. parapsilosis, and C. glabrata release bona fide chemoattractants for PMNs. S. cerevisiae, however, releases a chemokinetic factor but not a chemoattractant. Characterization of the C. albicans chemoattractant revealed that it is a peptide of approximately 1 kDa. Whereas the mating type of C. albicans did not affect the release of chemoattractant, switching did. White-phase cells released chemoattractant, but opaque-phase cells did not. Since the opaque phase of C. albicans represents the mating-competent phenotype, it may be that opaque-phase cells selectively suppress the release of chemoattractant to facilitate mating.
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Kraus-Friedmann, N., S. Higham, and C. R. Fleschner. "Hormonal stimulation of Ca2+ release from the perfused liver: effects of uncoupler." American Journal of Physiology-Gastrointestinal and Liver Physiology 258, no. 1 (January 1, 1990): G73—G77. http://dx.doi.org/10.1152/ajpgi.1990.258.1.g73.
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Administration of vasopressin and glucagon evokes a transient release of Ca2+ from perfused livers. The Ca2+ is released from a pool that is depletable by the mitochondrial uncoupler carbonyl cyanide p-trifluoromethoxyphenylhydrazone (FCCP). Therefore, the mechanism of the FCCP-stimulated Ca2+ release was examined. The FCCP-stimulated Ca2+ release was associated with a decrease in ATP levels. In the presence of oligomycin, which blocked the FCCP-induced rapid ATP breakdown, FCCP did not release Ca2+ though it still stimulated respiration. The possibility that FCCP might indirectly cause a release of Ca2+ by lowering hepatic ATP was examined at two levels of organization: 1) in the whole organ, by perfusing livers with fructose, a compound that was shown previously to drastically lower ATP in the liver, and 2) in isolated microsomal vesicles by depleting ATP with glucose and hexokinase. Fructose evoked Ca2+ release from the perfused liver. Similarly, depletion of ATP by the addition of glucose and hexokinase evoked a rapid release of the accumulated Ca2+ from microsomal vesicles probably by the inhibition of the Ca2(+)-ATPase. These results demonstrate that the major mechanism by which FCCP releases Ca2+ in intact cells is by lowering ATP levels.
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Altmann, M. "GAIA DR2 - THE FIRST MAIN COURSE." Revista Mexicana de Astronomía y Astrofísica Serie de Conferencias 52 (October 5, 2020): 1–4. http://dx.doi.org/10.22201/ia.14052059p.2020.52.01.
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Gaia DR2, released on April 25th 2018 is the first full Gaia release with 1.3 billion stars having measured 5-parameter astrometry and 3-band photometry. Therefore the impact of this dataset is revolutionary, following the already highly successful but limited first data release from 2016. In my presentation, I will give an overviewof the data within Gaia DR2, its strengths, some exemplary show cases, and also some limitations of this dataand astrometric data overall. Finally I will look ahead to the next Gaia releases.
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Hoddle, M. S., J. P. Sanderson, and R. G. Van Driesche. "Biological control ofBemisia argentifolii(Hemiptera: Aleyrodidae) on poinsettia with inundative releases ofEretmocerus eremicus(Hymenoptera: Aphelinidae): does varying the weekly release rate affect control?" Bulletin of Entomological Research 89, no. 1 (January 1999): 41–51. http://dx.doi.org/10.1017/s0007485399000061.
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AbstractThe effectiveness of varying weekly release rates of the parasitoidEretmocerus eremicusRose & Zolnerowich for control ofBemisia argentifoliiBellows & Perring on poinsettias was determined. Two variable release rate strategies forE. eremicuswere evaluated: a low–high and a high–low release regimen. In the low–high treatment, one female parasitoid was released per plant per week for seven weeks, then the release rate was increased to five female parasitoids per plant per week for the remaining seven weeks of the trial. In the high–low treatment, five female parasitoids per plant per week were released for the first seven weeks, then the release rate was reduced to one female parasitoid per plant per week for the final seven weeks of the trial. Both release rates averaged three female parasitoids per plant per week. Life-tables were made forB. argentifoliiin the presence and absence of parasitoids. In the absence ofE. eremicus, egg to adult survivorship forB. argentifoliiwas 65%. In low–high release greenhouses, average egg to adult survivorship forB. argentifoliiwas 6% and parasitism was 28%. In high–low greenhouses, average egg to adult survivorship forB. argentifoliiwas 5% and parasitism was 16%. Average net reproductive rates forB. argentifoliiin the absence of parasitoids was 17 indicating a rapidly increasing population. Net reproductive rates were 1.46 and 1.24 for low–high and high–low release greenhouses, respectively, indicating substantially reducedB. argentifoliipopulation growth. At week 14 of the trial, densities of live nymphs and pupae were lower in high–low greenhouses when compared to low–high greenhouses. Better whitefly control is achieved with inundative releases ofE. eremicuswhen this natural enemy acts as a predator as opposed to a parasitoid.
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Lilly, L. B., and J. L. Gollan. "Ryanodine-induced calcium release from hepatic microsomes and permeabilized hepatocytes." American Journal of Physiology-Gastrointestinal and Liver Physiology 268, no. 6 (June 1, 1995): G1017—G1024. http://dx.doi.org/10.1152/ajpgi.1995.268.6.g1017.
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Inositol 1,4,5-trisphosphate [Ins(1,4,5)P3] is a second messenger that releases Ca2+ from hepatocyte microsomes. The toxic alkaloid ryanodine modulates Ca2+ release via a receptor (RyR) identified in a variety of cell systems, but its regulation and functional significance in liver are undefined. Similarly, the role in hepatocyte Ca2+ regulation of adenosine 5'-cyclic diphosphate-ribose (cADPR), which is the putative endogenous ligand for RyR in other cell systems, has not been defined. Utilizing microsomes and permeabilized cells, we have investigated Ca2+ regulation in hepatocytes and, in particular, effects of ryanodine, cADPR, and other putative modulators on Ca2+ release and compared these with Ins(1,4,5)P3-induced Ca2+ release. Ryanodine at > or = 50 microM released 20% of microsomal Ca2+, and, in contrast to Ins(1,4,5)P3, no potentiation was observed with guanosine 5'-triphosphate and polyethylene glycol. Ins(1,4,5)P3-induced Ca2+ release was demonstrable after maximal ryanodine-induced Ca2+ release, suggesting that distinct Ca2+ stores are involved. cADPR (5 microM) did not induce Ca2+ release, alone or in combination with calmodulin or hepatic cytosol, nor did it influence ryanodine-induced release, in microsomes or permeabilized hepatocytes (in which ryanodine released 25% of the sequestered Ca2+). Ryanodine-induced Ca2+ release in microsomes was not influenced by 20 mM caffeine, which itself did not mobilize Ca2+, but was prevented by 500 microM tetracaine, which was shown to induce Ca2+ release. We conclude that ryanodine is capable of mobilizing Ca2+ in the hepatocyte from microsomal stores that are distinct from those that can be regulated by Ins(1,4,5)P3 but that cADPR has no such effect. These data suggest that cADPR does not serve as the endogenous ligand for RyR in liver cells or that the site of action of ryanodine in hepatocyte microsomes is distinct from that in other cell types.
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Nagarkatti, Sudha, Patrick C. Tobin, Michael C. Saunders, and Andrew J. Muza. "Release of native Trichogramma minutum to control grape berry moth." Canadian Entomologist 135, no. 4 (August 2003): 589–98. http://dx.doi.org/10.4039/n02-099.
Full textAbstract:
AbstractWe studied the effects of inundative releases of the egg parasitoid Trichogramma minutum Riley (Hymenoptera: Trichogrammatidae) on economic injury by grape berry moth, Endopiza viteana (Clemens) (Lepidoptera: Tortricidae). Trichogramma minutum originally collected from natural host populations near North East, Pennsylvania, was mass produced in tobacco hornworm hosts and Mediterranean flour moth. We released T. minutum in border rows, where grape berry moth infestation is typically high, of experiment field station and commercial vineyards from 1996 to 1999. We recorded significant reductions in economic injury in plots where parasitoids were released. In vineyards with low to moderate grape berry moth abundance, four releases during the growing season were adequate in reducing damage at harvest to below 3%. In high-risk vineyards, T. minutum releases reduced damage to levels below 15%. The use of buckwheat as a cover crop to provide nectar in combination with parasitoid releases showed potential benefits in parasitoid activity. A biocarrier and Biosprayer™ were used in mechanized parasitoid-release operations, and no adverse effect on parasitoid emergence was recorded from parasitized eggs using this approach.
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Whayman, Derek. "The modern rule of releases." Legal Studies 41, no. 3 (April 8, 2021): 493–510. http://dx.doi.org/10.1017/lst.2021.18.
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AbstractThis paper considers the history and nature of the ‘modern rule of releases’, concerning compromises to settle or preclude litigation. The rule holds that only matters the parties had contemplated as well as what they intended to release will in fact be released, even if the compromise has been made in the most general terms. Thus the rule is engaged when the releasor executes a general release but does not appreciate the existence of some of the claims the words used purport to release. This paper shows how the rule is a confusion of different conceptual bases and lines of authority and was created by accidentally muddling them together. It argues that, despite this, it successfully straddles both bases, functions well conceptually and serves a vital role.
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Lebata, Ma Junemie Hazel L., Lewis Le Vay, Mark E. Walton, Joseph B. Biñas, Emilia T. Quinitio, Eduard M. Rodriguez, and Jurgenne H. Primavera. "Evaluation of hatchery-based enhancement of the mud crab, Scylla spp., fisheries in mangroves: comparison of species and release strategies." Marine and Freshwater Research 60, no. 1 (2009): 58. http://dx.doi.org/10.1071/mf08155.
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Ranching, stock enhancement and restocking are management approaches involving the release of wild or hatchery-bred organisms to enhance, conserve or restore fisheries. The present study, conducted from April 2002 to November 2005, evaluated the effectiveness of releasing wild and hatchery-reared (HR) mud crabs in the mangroves of Ibajay, Aklan, Philippines where preliminary studies demonstrated declining fishery yields, abundance and size of crabs. Comparison of survival and growth of wild-released and HR Scylla olivacea and HR Scylla serrata demonstrated the effect of nursery conditioning, size-at-release and species differences. Overall yield and catch per unit effort (CPUE) increased by 46% after stock enhancement trials. Recapture rates of released crabs were highest in wild-released S. olivacea and in crabs measuring 65.0–69.9 mm carapace width (CW) and lowest in non-conditioned HR S. serrata. Growth rates were highest for conditioned HR S. olivacea and lowest for conditioned HR S. serrata (11.7 and 3.7 mm month–1 respectively). Fishing mortality was highest for S. olivacea, whereas natural mortality was greater for S. serrata. Conditioning hatchery-bred animals before release is also important in obtaining higher survival. S. olivacea was the more appropriate of the two species for release in mangrove habitats inundated with low-salinity water. However, there is a need for site-specific studies to evaluate the effectiveness of releases.
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Leduc, L. E., and R. D. Zipser. "Tissue origin of peptide-responsive eicosanoid production in rabbit intestine." American Journal of Physiology-Gastrointestinal and Liver Physiology 257, no. 6 (December 1, 1989): G879—G886. http://dx.doi.org/10.1152/ajpgi.1989.257.6.g879.
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Different layers of rabbit large and small intestine display different peptide sensitivity and different profiles of eicosanoid release. Isolated perfused mesenteric pedicle alone, with muscularis/submucosa or with muscularis and mucosa from normal small bowel, normal colon, or inflamed colon were stimulated with bradykinin (BK) or n-formyl-methionyl-leucyl-phenylalanine (fMLP). Released prostaglandin (PG)E2, thromboxane (Tx)B2, and leukotriene (LT)B4 were assayed using extensively validated radioimmunoassays. In rabbit colon, PGE2 arises primarily from the mesentery, while in small intestine the muscularis/mucosa releases 70-80% of the total PGE2. BK releases no significant thromboxane from healthy colon, although both muscularis/submucosa and mucosa respond in inflamed colon. In contrast, fMLP stimulates thromboxane from muscularis/submucosa and mucosa of even healthy colon, while release is greatly potentiated in inflammation. Lipoxygenase in the colon is regulated differently than cyclooxygenase; it is not stimulated by BK in either healthy or inflamed colon. fMLP releases equal amounts of LTB4 from healthy and inflamed colon, but release was primarily from healthy colonic mucosa, whereas it was distributed throughout mesenteric pedicle, muscularis, and mucosa in inflamed colon. The ability of normal colonic mucosa to release proinflammatory LTB4 in response to a chemotactic factor (fMLP) produced by enteric bacteria suggests a possible role for these compounds as a stimulus for inflammation in some patients with inflammatory bowel disease.
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Grabner, Chad P., and Aaron P. Fox. "Stimulus-Dependent Alterations in Quantal Neurotransmitter Release." Journal of Neurophysiology 96, no. 6 (December 2006): 3082–87. http://dx.doi.org/10.1152/jn.00017.2006.
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Neurotransmitter release is a steep function of the intracellular calcium ion concentration ([Ca2+]i) at the release sites. Both the Ca2+ amplitude and the time course appear to be important for specifying neurotransmitter release. Ca2+ influx regulates the number of vesicles exocytosed as well as the amount of neurotransmitter each individual vesicle releases. In our study we stimulated mouse chromaffin cells in two different ways to alter Ca2+ presentation at the release sites. One method, digitonin permeabilization followed by exposure to Ca2+, allows for a large uniform global elevation of [Ca2+]i, whereas the second method, application of nicotine, depolarizes chromaffin cells and activates voltage-dependent Ca2+ channels, thereby producing more phasic and localized changes in [Ca2+]i. Using amperometry to monitor catecholamine release, we show that both kinds of stimuli elicit the exocytosis of similar quantities of neurotransmitter per large dense core vesicles (LDCVs) released. Even so, the release process was quite different for each stimulus; nicotine-elicited events were small and slow, whereas digitonin events were, in comparison, large and fast. In addition, the transient opening of the fusion pore, called the “foot,” was essentially absent in digitonin-stimulated cells, but was quite common in nicotine-stimulated cells. Thus even though both strong stimuli used in this study elicited the release of many vesicles it appears that the differences in the Ca2+ levels at the release sites were key determinants for the fusion and release of individual vesicles.
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Floate, K. D. "Field trials of Trichomalopsis sarcophagae (Hymenoptera: Pteromalidae) in cattle feedlots: a potential biocontrol agent of filth flies (Diptera: Muscidae)." Canadian Entomologist 135, no. 4 (August 2003): 599–608. http://dx.doi.org/10.4039/n02-093.
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AbstractA field study was performed in southern Alberta, Canada, to assess the native wasp, Trichomalopsis sarcophagae (Gahan), as a potential biocontrol agent for house fly, Musca domestica L., and stable fly, Stomoxys calcitrans (L.). The wasp was readily reared in large numbers, which allowed for the cumulative release of an estimated 4.63 million wasps into three commercial feedlots during the 2-year study. Each of several releases predictably and repeatedly enhanced parasitism of sentinel house fly pupae, whereas parasitism remained low in three paired control feedlots where wasps were not released. Releases every 2nd week had a disproportionately greater effect than releases every 2nd month. In 1998, 1.2 million wasps were released into treatment feedlots resulting in the recovery of 3 952 T. sarcophagae from 31 500 sentinel pupae (0.13 wasps/pupa). In 1999, 3.43 million wasps were released into treatment feedlots, with the recovery of 37 763 wasps from 47 720 sentinel pupae (0.79 wasps/pupa). Hence, a 2.8-fold increase in the number of wasps released in 1999 resulted in a 6.1-fold increase in the recovery of wasps. This result supports industry recommendations of regular, repeated releases of wasps every 2nd or 4th week versus one or infrequent releases throughout the summer. There was no evidence that releases augmented overwintering populations of the wasp in subsequent years. These results provide proof-of-concept for the mass-rearing and release of T. sarcophagae as an inundative biocontrol agent for the control of pest flies in cattle confinements. Further studies will be required to assess the effect of T. sarcophagae releases on natural populations of pest flies.
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Bucur, C., C. Ichim, and I. Florea. "14C Release from TRIGA irradiated graphite." Radiocarbon 60, no. 6 (November 21, 2018): 1819–29. http://dx.doi.org/10.1017/rdc.2018.131.
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ABSTRACTLeaching tests were carried out in aerobic and anaerobic conditions to assess the 14C released from TRIGA irradiated graphite. Both total 14C and inorganic and organic fractions in the leachant solutions were measured. The experimental results obtained from the leaching tests confirm the low 14C release rate in alkaline environment. Less than 2% of the total 14C inventory in the specimens subject to the leaching tests was released as dissolved species. Both inorganic and organic 14C species are released in alkaline conditions, with more inorganic 14C release under aerobic conditions (around 68% of the total 14C released was released as inorganic dissolved species), and more organic 14C species in anaerobic conditions (around 65% of the total 14C released was released as organic dissolved species). Both for anaerobic and aerobic conditions, the leaching rates are high in the first days of immersion and decrease after that, indicating a two stage process: an initial quick release (less than 9 × 10–02 % of inventory/day for the first 48 days) followed by a slower release rate (around 4 × 10–03 % of inventory/day).
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Doi, Wataru, Akira Mizutani, and Hiroyoshi Kohno. "Larval release rhythm of the land hermit crab Coenobita cavipes Stimpson, 1858 (Anomura, Coenobitidae) on Iriomote Island, Japan." Crustaceana 91, no. 2 (2018): 199–211. http://dx.doi.org/10.1163/15685403-00003758.
Full textAbstract:
The larval release behaviour of Coenobita cavipes Stimpson, 1858 was studied on Iriomote Island, Japan between June and September 2012. The larval release was observed for several days before and after the new and full moons between July and August and showed semi-lunar rhythms. The larval release occurred 1-3 h after sunset and the peak time was almost 30 min earlier in August than in July. The time was not synchronised with nocturnal high tides in earlier and later days in each phase of syzygy. Emerging from residual lowland forests behind the coast, ovigerous females walked towards the river’s water edge and released larvae at the swash zone on the riverbank in the lower river. Therefore, they do not need to synchronise the larval release to coincide with the timing of high tide, unlike their congeneric nearest neighbour, C. violascens Heller, 1862, which releases larvae on the mangrove roots in the upper river.