Academic literature on the topic 'Regulatory T cells; immunology'
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Journal articles on the topic "Regulatory T cells; immunology"
Simpson, S. J. "IMMUNOLOGY: Animating Regulatory T cells." Science 289, no. 5479 (July 28, 2000): 509a—509. http://dx.doi.org/10.1126/science.289.5479.509a.
Full textBluestone, Jeffrey A., and Harald von Boehmer. "Regulatory T cells." Seminars in Immunology 18, no. 2 (April 2006): 77. http://dx.doi.org/10.1016/j.smim.2006.01.003.
Full textScott, David W. "T regulatory cells turn on T regulatory cells." Blood 114, no. 19 (November 5, 2009): 3975–76. http://dx.doi.org/10.1182/blood-2009-09-241406.
Full textSchumacher, Anne, and Ana Claudia Zenclussen. "Regulatory T Cells: Regulators of Life." American Journal of Reproductive Immunology 72, no. 2 (March 24, 2014): 158–70. http://dx.doi.org/10.1111/aji.12238.
Full textSakaguchi, Shimon. "Regulatory T cells." Springer Seminars in Immunopathology 28, no. 1 (August 5, 2006): 1–2. http://dx.doi.org/10.1007/s00281-006-0043-2.
Full textAl Dulaijan, Basmah S., Amr Mansouri, Jordan Karnyski, and Jamil Azzi. "Regulatory T cells." Current Opinion in Organ Transplantation 23, no. 1 (February 2018): 1–7. http://dx.doi.org/10.1097/mot.0000000000000491.
Full textAllez, Matthieu, and Lloyd Mayer. "Regulatory T Cells." Inflammatory Bowel Diseases 10, no. 5 (September 2004): 666–76. http://dx.doi.org/10.1097/00054725-200409000-00027.
Full textGarin, Marina I., and Robert I. Lechler. "Regulatory T cells." Current Opinion in Organ Transplantation 8, no. 1 (March 2003): 7–12. http://dx.doi.org/10.1097/00075200-200303000-00003.
Full textLui, Prudence PokWai, Inchul Cho, and Niwa Ali. "Tissue regulatory T cells." Immunology 161, no. 1 (June 24, 2020): 4–17. http://dx.doi.org/10.1111/imm.13208.
Full textMaggi, Enrico, Lorenzo Cosmi, Francesco Liotta, Paola Romagnani, Sergio Romagnani, and Francesco Annunziato. "Thymic regulatory T cells." Autoimmunity Reviews 4, no. 8 (November 2005): 579–86. http://dx.doi.org/10.1016/j.autrev.2005.04.010.
Full textDissertations / Theses on the topic "Regulatory T cells; immunology"
Lindqvist, Camilla. "T Regulatory Cells – Friends or Foes?" Doctoral thesis, Uppsala universitet, Enheten för klinisk immunologi, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-128837.
Full textSayin, Ismail. "Characterization of human T follicular regulatory cells." Case Western Reserve University School of Graduate Studies / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=case1560336991188191.
Full textEmani, Sirisha. "MOLECULAR CHARACTERIZATION OF T REGULATORY CELLS IN FIV-INFECTION." NCSU, 2006. http://www.lib.ncsu.edu/theses/available/etd-01192006-105756/.
Full textRaynor, Jana L. "Regulatory T Cell Homeostasis in Aging." University of Cincinnati / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1416570329.
Full textChen, Ye. "Induced regulatory T cells in transplantation tolerance." Thesis, University of Oxford, 2010. http://ora.ox.ac.uk/objects/uuid:cffc275b-d32c-495e-a1da-55421a57e7e7.
Full textAlexander, Carla-Maria Alana. "T regulatory cells and the germinal center." Diss., University of Iowa, 2011. https://ir.uiowa.edu/etd/1117.
Full textStefkova, Martina. "Regulatory T cells control the CD4 T cell repertoire." Doctoral thesis, Universite Libre de Bruxelles, 2016. https://dipot.ulb.ac.be/dspace/bitstream/2013/233151/3/Table.pdf.
Full textRecent studies conducted in mice and humans have suggested a role for the TCR repertoire diversity in immune protection against pathogens displaying high antigenic variability. To study the CD4 T cell repertoire, we used a mouse model in which T cells transgenically express the TCRβ chain of a TCR specific to a MHCII-restricted peptide, env122-141. Upon immunization with peptide-pulsed dendritic cells, antigen-specific Vα2+ CD4+ T cells rapidly expand and display a restricted TCRα repertoire. In particular, analysis of receptor diversity by high-throughput TCR sequencing in immunized mice suggests the emergence of a broader CDR3 Vα2 repertoire in Treg-depleted mice. These results suggest that Tregs may play a role in the restriction of the CD4 T cell repertoire during an immune response, raising therefore the possibility that in addition to controlling the magnitude of an immune response, regulatory cells may also control the diversity of TCRs in response to antigen stimulation.
Doctorat en Sciences
info:eu-repo/semantics/nonPublished
Okeke, Emeka B. "Regulation of Sepsis and Endotoxic Shock by Regulatory T cells." Wolters Kluwer Health Lippincott Williams & Wilkins, 2013. http://hdl.handle.net/1993/31580.
Full textOctober 2016
Chatila, Wissam M. "MicroRNA expression in regulatory T cells in chronic obstructive pulmonary disease." Thesis, Temple University, 2015. http://pqdtopen.proquest.com/#viewpdf?dispub=3719335.
Full textCOPD is characterized by an abnormal regulatory T cell (Treg) response with a shift towards a Th1 and Th17 cell responses. However, it is unclear if the function of Treg cells is impaired by smoking and in COPD. In addition, the miRNA profile of Treg cells in COPD is unknown and whether miRNA deregulation contributes to COPD immunopathogenesis. We set the objective to study Treg cell function isolated from peripheral blood of patients with COPD versus controls and to compare their miRNA profiles. We also were interested in exploring the function of some of the differentially expressed Treg cell miRNAs. We assessed the Treg cell function by observing their suppressive activity on autologous effector T cells and analyzed their miRNA expression initially by microarray analysis then conducted real time RT-PCR validation for selected miRNAs. In Silico target gene analysis for the validated miRNAs suggested that miR-199-5p is particularly relevant to Treg cell physiology so its function was investigated further using CCD-986Sk and MOLT-4 cells. We found no difference in Treg cell function between COPD and controls but we were able to identify 6 and 96 miRNAs that were differentially expressed in COPD versus control Treg cells. We confirmed that miR-199a-5p was repressed by approximately 4 fold in Treg cells of COPD patients compared to cells in healthy smokers. Importantly, miR-199a-5p had significant overrepresentation of its target genes in the Treg cell transcriptome, with many targets associated with the TGF-β activation pathway. We also confirmed the function of miR-199a5p in an in-vitro loss-of-function cell model running TaqMan® arrays of the Human TGF-β Pathway. These findings suggest that the abnormal repression of miR-199a-5p in patients with COPD compared to unaffected smokers may be involved in modulating the adaptive immune balance in favor of a Th1 and Th17 response.
Lee, Crystal. "Suppressive activity of CD4+Foxp3+ regulatory T cells in an animal model of spontaneous CD8+ T cell-mediated demyelinating disease." Thesis, McGill University, 2012. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=110761.
Full textLe laboratoire du Dr. Fournier a généré une lignée de souris (les souris L31) qui développe de façon spontanée une maladie du système nerveux central qui conduit à la perte de la gaine de myéline et qui est dépendante de la presence de lymphocytes T. Dans ce modèle les lymphocytes CD8+ sont les cellules effectrices de la maladie tandis que les lymphocytes T CD4+ jouent un rôle régulateur. Il a été démontré qu'une sous-population de lymphocytes T CD4+ qui expriment le facteur de transcription Foxp3 est impliquée dans la regulation des réponses auto-immunes. Afin d'étudier le rôle de cette population dans le développement de la maladie neurologique des souris L31, le but de mon projet de recherche était de caractériser de façon fonctionelle cette sous-population de lymphocytes T CD4+ régulateurs des souris L31. Nous avons trouvé que les lymphocytes T régulateurs des souris L31 sont altérés dans leur capacité à supprimer la proliferation de cellules T effectrices in vitro. Ceci est dû en partie à leur expression elevée de la protein B7.2 (CD86). Cependant, les lymphocytes T régulateurs des souris L31 sont capables de prévenir le développement des symptômes neurologiques in vivo. Donc, bien que les lymphocytes T régulateurs des souris L31 ne sont pas suppresseurs in vitro, notre données in vivo suggèrent qu'ils ont une fonction régulatrice dans le développement de la maladie neurologique des souris L31. Cette dichotomie pourrait nous permettre de déterminer les mécanismes utilisés par ces cellules régulatrices pour contrôler le développement de la maladie neurologique auto-immune dans les souris L31.
Books on the topic "Regulatory T cells; immunology"
Regulatory T cells: Methods and protocols. [New York]: Humana Press, 2011.
Find full textNa, Songqing, and Chandrasekar Venkataraman Iyer. Effector CD4+ T cells in health and disease 2007. Kerala, India: Transworld Research Network, 2007.
Find full textI, Gabrilovich Dmitry, and Hurwitz Arthur A, eds. Tumor-induced immune suppression: Mechanisms and therapeutic reversal. New York, NY: Springer, 2008.
Find full textOno, Masahiro, ed. Regulatory T-Cells. New York, NY: Springer US, 2023. http://dx.doi.org/10.1007/978-1-0716-2647-4.
Full textKassiotis, George, and Adrian Liston, eds. Regulatory T Cells. Totowa, NJ: Humana Press, 2011. http://dx.doi.org/10.1007/978-1-61737-979-6.
Full textMarc, Feldmann, Lamb Jonathan R, and Owen M. J, eds. T cells. New York: Wiley, 1989.
Find full textTaams, Leonie S., Marca H. M. Wauben, and Arne N. Akbar, eds. Regulatory T Cells in Inflammation. Basel: Birkhäuser Basel, 2005. http://dx.doi.org/10.1007/b137037.
Full textJiang, Shuiping, ed. Regulatory T Cells and Clinical Application. New York, NY: Springer US, 2008. http://dx.doi.org/10.1007/978-0-387-77909-6.
Full textZanetti, M. Memory T cells. New York: Springer Science+Business Media, 2010.
Find full textDebré, P. Clonage des lymphocytes T. Paris: Societé française d'immunologie, 1989.
Find full textBook chapters on the topic "Regulatory T cells; immunology"
Gawlik, Barbara B., and David A. Hafler. "Regulatory T Cells in MS." In Multiple Sclerosis Immunology, 27–47. New York, NY: Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-7953-6_2.
Full textBrunner, M. C., D. Caput, M. R. Helbert, N. A. Mitchison, K. Simon, J. Sieper, and P. Wu. "Regulation of Regulatory T Cells." In Progress in Immunology Vol. VIII, 613–18. Berlin, Heidelberg: Springer Berlin Heidelberg, 1993. http://dx.doi.org/10.1007/978-3-642-51479-1_79.
Full textKim, Chang H. "Regulatory T-Cells and Th17 Cells in Tumor Microenvironment." In Cancer Immunology, 91–106. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-30845-2_6.
Full textKim, Chang H. "Regulatory T Cells and Th17 Cells in Cancer Microenvironment." In Cancer Immunology, 77–91. Berlin, Heidelberg: Springer Berlin Heidelberg, 2014. http://dx.doi.org/10.1007/978-3-662-44006-3_6.
Full textFowell, Deborah J. "Regulatory T Cell." In Encyclopedia of Medical Immunology, 955–63. New York, NY: Springer New York, 2014. http://dx.doi.org/10.1007/978-0-387-84828-0_340.
Full textPucino, Valentina, Veronica De Rosa, Claudio Procaccini, and Giuseppe Matarese. "Regulatory T Cells, Leptin and Angiogenesis." In Chemical Immunology and Allergy, 155–69. Basel: S. KARGER AG, 2013. http://dx.doi.org/10.1159/000353557.
Full textMassoud, Amir Hossein. "Age-Related Alterations in Regulatory T Cells." In Immunology of Aging, 201–6. Berlin, Heidelberg: Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-39495-9_13.
Full textEnders, G. A. "Regulatory T Cells in the Galt." In Recent Advances in Mucosal Immunology, 149–54. Boston, MA: Springer US, 1987. http://dx.doi.org/10.1007/978-1-4684-5344-7_17.
Full textKretschmer, Karsten, Irina Apostolou, Panos Verginis, and Harald von Boehmer. "Regulatory T Cells and Antigen-Specific Tolerance." In Chemical Immunology and Allergy, 8–15. Basel: KARGER, 2008. http://dx.doi.org/10.1159/000154846.
Full textStrickland, Deborah H., Matthew E. Wikstrom, Debra J. Turner, and Patrick G. Holt. "Mucosal Regulatory T Cells in Airway Hyperresponsiveness." In Chemical Immunology and Allergy, 40–47. Basel: KARGER, 2008. http://dx.doi.org/10.1159/000154855.
Full textConference papers on the topic "Regulatory T cells; immunology"
Li, Amy, Arjun Bhutkar, Nikhil S. Joshi, and Tyler E. Jacks. "Abstract A66: Molecular profiling of regulatory T cells in a genetic mouse model of lung adenocarcinoma." In Abstracts: AACR Special Conference on Tumor Immunology and Immunotherapy; October 20-23, 2016; Boston, MA. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/2326-6074.tumimm16-a66.
Full textHsieh, Chyi-Song. "Abstract IA06: Role of TCR specificity in regulatory T cell selection." In Abstracts: AACR Special Conference on Tumor Immunology and Immunotherapy; October 20-23, 2016; Boston, MA. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/2326-6074.tumimm16-ia06.
Full textNoël, Grégory, Mireille Langouo, Soizic Garaud, Anaïs Boisson, Hugues Duvillier, Gert Van den Eynden, Denis Larsimont, and Karen Willard-Gallo. "Abstract A40: The balance between activated follicular helper T cells and follicular regulatory T cells within tertiary lymphoid structures guides antitumor immune responses in human breast cancer." In Abstracts: AACR Special Conference on Tumor Immunology and Immunotherapy; November 27-30, 2018; Miami Beach, FL. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/2326-6074.tumimm18-a40.
Full textWard, Stephen T., Elizabeth A. Hepburn, Ka-kit Li, Stuart M. Curbishley, Rahul K. Hejmadi, Tariq Ismail, Roy Bicknell, Antal Rot, and David H. Adams. "Abstract A73: The selective recruitment and retainment of regulatory T cells in human colorectal cancer." In Abstracts: AACR Special Conference on Tumor Immunology: Multidisciplinary Science Driving Basic and Clinical Advances; December 2-5, 2012; Miami, FL. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.tumimm2012-a73.
Full textShahoei, Sayyed Hamed, Adam T. Nelson, Madeline A. Henn, Ashley E. Mathews, Joy J. Chen, Varsha Vembar, Liqian Ma, Lionel Apetoh, and Erik R. Nelson. "Abstract A93: Macrophage-expressed small heterodimer partner impairs expansion of regulatory T cells and enhances immune checkpoint inhibition." In Abstracts: AACR Special Conference on Tumor Immunology and Immunotherapy; November 17-20, 2019; Boston, MA. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/2326-6074.tumimm19-a93.
Full textSong, Qing-Kun, Jun Ren, Xiao-Li Wang, Xin-Na Zhou, Hua-Bing Yang, Yu-Chen Li, and Jiang-Ping Wu. "Abstract B14: CD4+CD25+ regulatory T lymphocytes: Prognostic indicator of Chinese breast cancer patients receiving dentitric cells-cytokine induced killer cells infusion." In Abstracts: AACR Special Conference: Tumor Immunology and Immunotherapy: A New Chapter; December 1-4, 2014; Orlando, FL. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/2326-6074.tumimm14-b14.
Full textDas, Satya N., Sadhna Aggarwal, and Suresh C. Sharma. "Abstract A67: Phenotypic and functional dynamics of CD4+CD25+FOXP3+ regulatory T cells in patients with tobacco-related oral squamous cell carcinoma." In Abstracts: AACR Special Conference on Tumor Immunology and Immunotherapy; October 20-23, 2016; Boston, MA. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/2326-6074.tumimm16-a67.
Full textZhang, Hongru, Jun Gui, Angelica Ortiz, and Serge Fuchs. "Abstract A100: Downregulation of type 1 interferon receptor (IFNAR1) regulates the balance of regulatory T cells (Tregs) and cytotoxic T lymphocytes (CTLs) in tumor microenvironment." In Abstracts: AACR Special Conference on Tumor Immunology and Immunotherapy; November 17-20, 2019; Boston, MA. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/2326-6074.tumimm19-a100.
Full textPark, Chan Kwon, and Seung Joon Kim. "Abstract B70: Differential expression of regulatory T cells and Th17 cells are indicative of tumor recurrence in pN0 stage I lung cancer patients." In Abstracts: AACR Special Conference on Tumor Immunology and Immunotherapy; November 27-30, 2018; Miami Beach, FL. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/2326-6074.tumimm18-b70.
Full textHope, Jennifer L., Dennis C. Otero, Eun-ah Bae, Christopher J. Stairiker, Ashley B. Palete, Hannah A. Faso, Petrus de Jong, Garth Powis, and Linda M. Bradley. "Abstract PO014: PSGL-1 is an early T cell signaling regulator that drives immunometabolism and terminal differentiation in tumor-specific CD8 T cells." In Abstracts: AACR Virtual Special Conference: Tumor Immunology and Immunotherapy; October 19-20, 2020. American Association for Cancer Research, 2021. http://dx.doi.org/10.1158/2326-6074.tumimm20-po014.
Full textReports on the topic "Regulatory T cells; immunology"
Wong, Jr, and K. K. Regulatory T Cells and Host Anti-CML Responses. Fort Belvoir, VA: Defense Technical Information Center, June 2008. http://dx.doi.org/10.21236/ada487614.
Full textWong, Jr, and K. K. Regulatory T Cells and Host Anti-CML Responses. Fort Belvoir, VA: Defense Technical Information Center, June 2009. http://dx.doi.org/10.21236/ada510759.
Full textLorenz, Ulrike. Role of the Tyrosine Phosphatase SHP-1 and Regulatory T Cells in Breast Cancer. Fort Belvoir, VA: Defense Technical Information Center, September 2008. http://dx.doi.org/10.21236/ada501068.
Full textLorenz, Ulrike. Role of the Tyrosine Phosphatase SHP-1 and Regulatory T Cells in Breast Cancer. Fort Belvoir, VA: Defense Technical Information Center, September 2007. http://dx.doi.org/10.21236/ada510570.
Full textSusurkova, Rumyana, Andrey Velichkov, Antoaneta Mihova, Maria Muhtarova, Matgarita Guenova, Iskra Antonova, Georgi Nikolov, and Velislava Terzieva. Phosphorilated STAT5 Is Associated with Differential Activation Capacity of T Regulatory Cells in Women with Re productive Failure. "Prof. Marin Drinov" Publishing House of Bulgarian Academy of Sciences, March 2021. http://dx.doi.org/10.7546/crabs.2021.03.15.
Full textFicht, Thomas, Gary Splitter, Menachem Banai, and Menachem Davidson. Characterization of B. Melinensis REV 1 Attenuated Mutants. United States Department of Agriculture, December 2000. http://dx.doi.org/10.32747/2000.7580667.bard.
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