Academic literature on the topic 'Regulatory search'

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Journal articles on the topic "Regulatory search"

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Jiao, Lu, Kevin Baird, and Graeme Harrison. "Searching in the regulatory environment: The impact of regulatory search on firm innovativeness." Australian Journal of Management 45, no. 1 (July 9, 2019): 153–71. http://dx.doi.org/10.1177/0312896219857458.

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This article examines the effect of regulatory search on firm innovativeness using survey data from Chief Executive Officers (CEOs) of Australian listed and private firms. We used a self-developed scale to measure regulatory search, which consists of both reactive and proactive regulatory search. The results show that only reactive regulatory search exhibits a positive and direct association with firm innovativeness. However, the results suggest that slack moderates the relations between the two regulatory search factors and innovativeness in different ways. Specifically, under a high (low) slack environment, reactive regulatory search is negatively (positively) related to innovativeness, while, under a high (low) slack environment, proactive regulatory search is positively (negatively) related to innovativeness. JEL Classification: L51, O31
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Us, M. V., and I. A. Titko. "Protection of Economic Competition and Intellectual Property: Search for an Optimal Regulatory Model." Science and innovation 15, no. 2 (April 22, 2019): 41–51. http://dx.doi.org/10.15407/scine15.02.041.

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Boscheck, Ralf. "Patent Trolls: In Search of Efficient Regulatory Standards." World Competition 39, Issue 1 (March 1, 2016): 67–84. http://dx.doi.org/10.54648/woco2016005.

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Current concerns about the growth of patent assertion entities (PAEs) are typically related to their presumed anti-competitive behaviour and negative impact on innovation in product and technology markets. Regulators, required to balance the legitimate interests of patent holders and licensees, call for evidentiary standards to efficiently appraise, and for the purpose of policy formulation, prejudge the reasonableness and welfare consequences of these undertakings. And yet, recent economic analyses still seem far from offering operational criteria that could translate into enforceable, let alone efficient, regulatory norms. And so, case analysis, particularly in the US context, turns into an ordeal trying to tweak the facts of these fairly new business models to suit time-honoured legal principles. Plainly, PAE efforts in general do not seem to be easily caught by US competition rules that assign antitrust liability based on harm to competition and the competitive process. This is not to suggest that they are pro-competitive per se but, rather, that any attack on them may give rise to ‘administratively hopeless, but generally exculpating, rule of reason defence’. It may be for that reason that US judicial, federal and state reforms – for better or for worse – have begun to target some of the leverage points and key drivers of the PAE business model.The welfare consequences of reduced IP enforcement will still need to be established. The EU Commission expects PAEs to be less active in Europe because of the loser pays principle in European courts, the smaller damage awards offered in successful cases, and because of the higher degree of predictability of outcomes in European specialist patent courts. Yet, similar to the US context, EU regulators are faced with the dilemma of devising standards that fit a variety of circumstances and yet can be easily applied. In both cases, regulatory delegation avoids the pitfalls of ordering complexities centrally. But it requires a set of simple meta-rules to guide lower-level decisions, adjust principles to circumstance and keep matters predictable. Delegation in the area of competition policy is limited by the adequacy of the economic reference that it employs. At this stage, in dealing with outsourced patent assertion and related licensing conditions, economic theory offers a wide yet insufficient menu of advice. The article has four parts: Section 1 discusses patent trends, actors, rights and obligations, and the nature of current regulatory concerns. Section 2 reviews the scant empirical analyses and model work on patent trolls. Section 3 examines regulatory concerns in view of US antitrust standards and lists alternative remedies. Section 4 concludes and offers some considerations related to the European context.
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Ashmarin, I. P., and E. P. Karazeeva. "Search for evolutionary ancient, relict, regulatory peptides." Journal of Evolutionary Biochemistry and Physiology 43, no. 1 (February 2007): 123–25. http://dx.doi.org/10.1134/s0022093007010139.

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Tuan Pham, Michel, and Hannah H. Chang. "Regulatory Focus, Regulatory Fit, and the Search and Consideration of Choice Alternatives." Journal of Consumer Research 37, no. 4 (December 2010): 626–40. http://dx.doi.org/10.1086/655668.

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Parnes, Dror. "The search for an optimal RBC regulatory system." Journal of Financial Economic Policy 6, no. 1 (April 1, 2014): 78–92. http://dx.doi.org/10.1108/jfep-05-2013-0021.

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Purpose – The author assembles three hypothetical regulatory regimes and deploys computer simulations to contrast different banking systems based on conventional strategies for appointing risk-based capital minimum thresholds. The paper aims to discuss these issues. Design/methodology/approach – The author instigates cascading failure models within numerous directed graphs and measures the inflicted costs, the accumulated bank failures, and the general robustness of the networks following various economic shocks. Findings – The author finds that a homogeneous regulatory regime is an inferior approach. However, a selected too-big-to-fail scheme portrays the best defensive banking model with the lowest number of total bank failures and the fewest banks' costs and social costs. Research limitations/implications – The author can only theoretically examine this topic. Originality/value – The author overcomes some obstacles in prior studies including the use of a large and complex network and the proportional allocation of funds upon a bank failure.
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de la Rosa, Mario Diaz, and Andrew J. Spakowitz. "Target Site Search Strategy Of Gene Regulatory Proteins." Biophysical Journal 96, no. 3 (February 2009): 366a. http://dx.doi.org/10.1016/j.bpj.2008.12.1972.

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N. Mowle, Elyse, Emily J. Georgia, Brian D. Doss, and John A. Updegraff. "Application of regulatory focus theory to search advertising." Journal of Consumer Marketing 31, no. 6/7 (November 4, 2014): 494–502. http://dx.doi.org/10.1108/jcm-06-2014-1003.

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Purpose – The purpose of this paper is to test the utility of regulatory focus theory principles in a real-world setting; specifically, Internet hosted text advertisements. Effect of compatibility of the ad text with the regulatory focus of the consumer was examined. Design/methodology/approach – Advertisements were created using Google AdWords. Data were collected for the number of views and clicks each ad received. Effect of regulatory fit was measured using logistic regression. Findings – Logistic regression analyses demonstrated that there was a strong main effect for keyword, such that users were almost six times as likely to click on a promotion advertisement as a prevention advertisement, as well as a main effect for compatibility, such that users were twice as likely to click on an advertisement with content that was consistent with their keyword. Finally, there was a strong interaction of these two variables, such that the effect of consistent advertisements was stronger for promotion searches than for prevention searches. Research limitations/implications – The effect of ad compatibility had medium to large effect sizes, suggesting that individuals’ state may have more influence on advertising response than do individuals’ traits (e.g. personality traits). Measurement of regulatory fit was limited by the constraints of Google AdWords. Practical implications – The results of this study provide a possible framework for ad creation for Internet advertisers. Originality/value – This paper is the first study to demonstrate the utility of regulatory focus theory in online advertising.
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Baumbach, Jan, Karina Brinkrolf, Tobias Wittkop, Andreas Tauch, and Sven Rahmann. "CoryneRegNet 2: An Integrative Bioinformatics Approach for Reconstruction and Comparison of Transcriptional Regulatory Networks in Prokaryotes." Journal of Integrative Bioinformatics 3, no. 2 (December 1, 2006): 1–13. http://dx.doi.org/10.1515/jib-2006-24.

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SummaryCoryneRegNet is an ontology-based data warehouse of corynebacterial transcription factors and regulatory networks. Initially, it was designed to provide methods for the analysis and visualization of the gene regulatory network of Corynebacterium glutamicum. Now we integrated the genomes and transcriptional interactions of three other corynebacteria, C. diphtheriae, C. efficiens, and C. jeikeium into CoryneRegNet; providing comparative analysis and visualization with GraphVis. We also integrated the high-performance PSSM search tool PoSSuM search to detect potential transcription factor binding sites within and across species. As an application, we reconstruct in silico the regulatory network of the iron metabolism regulator DtxR in the four corynebacteria.CoryneRegNet is freely accessible at https://www.cebitec.uni-bielefeld.de/groups/gi/software/coryneregnet/. The final slash (/) is mandatory. In order to use the GraphVis feature, Java (at least version 1.4.2) is required.
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Charoenwong, Ben, Alan Kwan, and Tarik Umar. "Does Regulatory Jurisdiction Affect the Quality of Investment-Adviser Regulation?" American Economic Review 109, no. 10 (October 1, 2019): 3681–712. http://dx.doi.org/10.1257/aer.20180412.

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The Dodd-Frank Act shifted regulatory jurisdiction over “ midsize” investment advisers from the SEC to state-securities regulators. Client complaints against midsize advisers increased relative to those continuing under SEC oversight by 30 to 40 percent of the unconditional probability. Complaints increasingly cited fiduciary violations and rose more where state regulators had fewer resources. Advisers responding more to weaker oversight had past complaints, were located farther from regulators, faced less competition, had more conflicts of interest, and served primarily less-sophisticated clients. Our results inform optimal regulatory design in markets with informational asymmetries and search frictions. (JEL G24, G28, K22, L51, L84)
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Dissertations / Theses on the topic "Regulatory search"

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Başbuğ, Gökçe. "Essays on job search, unemployment, and regulatory compliance." Thesis, Massachusetts Institute of Technology, 2017. http://hdl.handle.net/1721.1/112038.

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Thesis: Ph. D., Massachusetts Institute of Technology, Sloan School of Management, 2017.
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This dissertation is composed of four essays, each studying limits to the means that are famously known to be effective. In the first essay, I investigate the effect of using social ties on the quality of opportunities pursued in job search. Using fixed effects models, I show that when the job seeker uses contacts, she pursues jobs that pay less than the jobs she pursues through formal methods. In addition, the analysis show that networks limit the geographical and occupational diversity of jobs pursued. In the second essay, using a mixed methods approach I examine how the negative emotional toll of long-term unemployment (LTU) is shaped by the interaction of gender and marital status. The interviews reveal a pattern with more marital tensions that exacerbate the emotional toll of LTU reported by married men than married women. The analysis of survey data show that overall marriages are helpful to the wellbeing of both unemployed men and women. Yet, for married men but not for married women, the analysis revealed that the significance of the benefits derived from marriage disappears once household income is controlled. The third essay examines whether introducing choice into a mandatory training program makes any difference in Unemployment Insurance recipients' job search performance. Using a field experiment design, I compare job search outcomes of individuals who have unconstrained workshop choices to others who only have a constrained option. Analyses show that providing the option of selecting which workshop to attend does not improve outcomes for unemployed. In the fourth essay, using data from safety inspections in laboratories at a large university, I investigate whether conducting semi-annual inspections and reporting findings back to responsible constituencies decreases the number of violations. The analyses show that the Environmental, Health, and Safety Management System did not reduce the number of violations. Rather, the results show a widening gap between compliant and non-compliant scientists. Using both lab-level quantitative data and interviews with inspectors and EHS personnel, I delineate the factors that impede the success of the system.
by Gökçe Başbuğ.
1. Do Social Networks Lead to Better Opportunities to Pursue? Evidence from Job Applications -- 2. The Emotional Toll of Long-Term Unemployment: Examining the Interaction Effects of Gender and Marital Status -- 3. Activation Programs for Unemployed Insurance Recipients: Comparison of Two Training Delivery Formats -- 4. Why Is Regulatory Compliance Difficult? Variable Performance and the Insulation of Economically Resourceful Actors.
Ph. D.
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Traisorat, Tull. "Supervisory and regulatory reform in Thailand's banking system : in search of regulatory sufficiency and effectiveness." Thesis, Queen Mary, University of London, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.314228.

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M'Barek, Sassi Amine. "Tax incentives and inter-state fiscal competition : the search for a regulatory framework." Thesis, University of Manchester, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.488365.

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The thesis represents a contribution to the debate on the regulation of inter-state fiscal competition. The study coincides with the mounting scepticism expressed towards the regulatory frameworks devised and implemented by the EU and OECD. This thesis offers a new and comprehensive approach to the regulatory dilemma. It looks at tax competition from a legal perspective and aspires at laying down the foundations of a balanced regulatory framework by sharing the burden of regulation amongst all parties involved in the process of fiscal competition. It also investigates the validity of the traditional arguments in the light of recent developments. Moreover, it tackles the one issue that is common to any regulatory framework, that is, the identification of tax incentives. The thesis contends that unless a common understanding is reached on what is meant by tax incentives, one may not seriously contemplate the regulation of inter-state fiscal competition.
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Götz, Matthias [Verfasser], Wolfgang [Gutachter] Wessels, and Chad [Gutachter] Damro. "In Search of Regulatory Compatibilities. The Constraints on the European Commission’s Strategies in Transatlantic Regulatory Cooperation / Matthias Götz ; Gutachter: Wolfgang Wessels, Chad Damro." Köln : Universitäts- und Stadtbibliothek Köln, 2018. http://d-nb.info/1173321942/34.

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Viana, Tiago Monteiro Lomba. "In search of role of yeast regulatory pathways during the last stages of wine fermentation." Doctoral thesis, ISA/UL, 2014. http://hdl.handle.net/10400.5/7321.

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Doutoramento em Engenharia Alimentar - Instituto Superior de Agronomia
While searching for roles of Saccharomyces cerevisiae regulatory pathways during the late stages of wine fermentation, a peculiar H+ homeostasis was found in an industrial wine strain, while fermenting natural grape must (NGM). Intracellular pH (pHi) of the population remained in the range 6.0 – 6.4, decreasing by the end of glucose fermentation (pHi 5.2 at 15oC), although cells remained viable. The plasma membranes of late stationary cells became almost impermeable to H+. To ensure replicability of subsequent experiments, a synthetic grape must was designed (ISA-SGM), in which we obtained similar fermentative profiles as in NGM for the wine strain and for laboratory strains. Fluorescence Ratio Imaging Microscopy (FRIM) was used to estimate pHi of individual cells of strain BY4741. Even at the end of fermentation, we found subpopulations with “healthy” cytosolic pH (i.e. pHi 6-7). Sixty-two single-deletion mutants of BY4741 were screened to identify genes required for optimal wine fermentation performance, leading to the identification of 10 determinants whose absence improved fermentation performance, while 37 were deleterious. Principal Component Analysis revealed that deletion of some genes involved in transcription, cell cycle and stress response led to improved performance, while reduced performance was associated mainly with genes involved in membrane functions.
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Jonsäll, Linnea. "Mutational analysis of the csgD mRNA leader: search for a mode of regulation." Thesis, Uppsala universitet, Institutionen för biologisk grundutbildning, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-208415.

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The CsgD protein is the master regulator of a pathway leading to the formation of curli, in essence regulating the switch between a motile and a sessile lifestyle for bacteria. The 5’-UTR region of the csgD mRNA is a hotspot for multiple regulatory small RNAs (sRNA) involved in a complex regulatory network. Even though it is previously known how the interaction takes place it is unknown how sRNA binding affects the translational activity. In order to suggest a mode of regulation a mutational assay was performed by making changes in the csgD 5’-UTR and investigate what the translational effects were. Mutations in different regions are shown to affect the translation levels in various ways.
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Acuña, Gonzalo. "Characterization of, and search for, new Bradyrhizobium japonicum genes : the fumarase gene fumC : unraveling the regulatory scope of NifA /." Zürich, 1990. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=9294.

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Thomas, Courtney Irene Powell. "The Problem with Purity: Market Failures, Foodborne Contamination, and the Search for Accountability in the U.S. Food Safety Regulatory Regime." Diss., Virginia Tech, 2010. http://hdl.handle.net/10919/26312.

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One of the great myths of contemporary U.S. culture is that America's food supply is the safest in the world. Another is that government agencies have the ability and authority to guarantee food safety and to enforce accountability standards upon food producers, processors, and distributors. But the U.S. food safety regulatory regime is as it has been for more than a century: embedded in the notions of food purity and wholesomeness that framed the 1906 Pure Food and Drug Act and the 1906 Federal Meat Inspection Act. Although changes in food production, processing, and distribution that occurred throughout the 20th century have rendered this regulatory regime ineffective and inefficient, efforts to amend its regulatory scope and power have been largely unsuccessful. Current proposals to transform this system, including the Food Safety Modernization Act of 2009 and the Food Safety Enhancement Act of 2009, however, would expand the power of government agencies to require process-based food safety systems, to test for contamination, to issue recalls, and to institute traceability protocols for all food products. Yet much of the economic literature critiques this top-down approach to regulation. Beginning with an overview of U.S. food safety and its regulation, this dissertation examines the relative effectiveness and efficiency of "top-down" "command and control" versus "bottom up" "market driven" regulatory regimes designed to resolve market failures and promote accountability relative to food safety. It includes an analysis of the impact and influence of food producing, processing, and distributing firms upon the policy process, examining when, why, and how large agri-food corporations support or oppose changes to the food safety regulatory regime and accountability framework, and concludes with an investigation of food safety crises as a catalyst for political change.
Ph. D.
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Chasiotis, Anita [Verfasser]. "I Want to Know Everything: Motivational and Self-Regulatory Determinants of the Intention to Comprehensively Search for Health Information / Anita Chasiotis." Trier : Universität Trier, 2020. http://d-nb.info/1217480129/34.

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Ruppert, Ann-Kathrin [Verfasser], Peter [Akademischer Betreuer] Nürnberg, Peter [Akademischer Betreuer] Schneider, and Peter [Akademischer Betreuer] Kloppenburg. "Integrative functional genomic search for regulatory DNA sequence polymorphisms influencing DNA methylation and mRNA expression in hippocampal brain tissue / Ann-Kathrin Ruppert. Gutachter: Peter Nürnberg ; Peter Schneider ; Peter Kloppenburg." Köln : Universitäts- und Stadtbibliothek Köln, 2015. http://d-nb.info/1084872617/34.

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Books on the topic "Regulatory search"

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Jackman, Henry N. R. Regulatory reform and the search for solvency. Kingston, Ont: John Deutsch Institute for the Study of Economic Policy, 1987.

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Maksurov, Aleksey. Coordination of the activities of legal entities in a crisis. ru: INFRA-M Academic Publishing LLC., 2022. http://dx.doi.org/10.12737/1836239.

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The monograph is devoted to the search for ways to improve the efficiency of public administration in crisis situations. The interrelation of the crisis situation with the problems of legal uncertainty and legally significant risks is traced. The article considers the substantive characteristics of the crisis as a social phenomenon, the causes and types of crisis situations, the problems of their legal definition, as well as the impact of the crisis on changes in the activities of public authorities and local self-government. A universal means of coordinating the activities of authorities and their officials in a crisis period is proposed - a mechanism of legal coordination. The analysis of the main shortcomings of the work of public authorities in a crisis, including in the situation of a pandemic of coronavirus infection, is made. The issues of the legality of restricting the constitutional rights of citizens in a crisis, the introduction of special legal regimes providing for other than usual ways, forms and limits of citizens' realization of their subjective rights are studied. Developed full-fledged detailed recommendations for improving law-making (proposed drafts of the necessary regulatory legal acts), the practice of interpretation and systematization of law, law enforcement, as well as control (supervisory) legal practice. For a wide range of readers interested in public administration issues in crisis situations. It can be useful for students, postgraduates and teachers of law schools.
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Gavaghan, Colin. Reproductive Technologies and the Search for Regulatory Legitimacy. Edited by Roger Brownsword, Eloise Scotford, and Karen Yeung. Oxford University Press, 2016. http://dx.doi.org/10.1093/oxfordhb/9780199680832.013.62.

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For a variety of reasons, assisted reproductive technologies (ARTs) have posed significant challenges to regulators seeking normative legitimacy. While some of those challenges relate to the sort of value pluralism common to many areas of life, it has been suggested that the challenge is made significantly harder by the presence of genuinely intractable normative problems. This chapter examines one of the most significant of these problems in relation to reproductive choices, the infamous Non Identity Problem. I examine a number of proposed solutions and regulatory strategies that have been examined to circumvent or resolve such problems, and conclude by suggesting that the extent of the challenge posed by non-identity is just beginning to become apparent.
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Trebilcock, Michael J. Paradoxes of Professional Regulation: In Search of Regulatory Principles. University of Toronto Press, 2022.

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Kanfer, Ruth, and Gina M. Bufton. Job Loss and Job Search: A Social-Cognitive and Self-Regulation Perspective. Edited by Ute-Christine Klehe and Edwin van Hooft. Oxford University Press, 2015. http://dx.doi.org/10.1093/oxfordhb/9780199764921.013.002.

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This chapter reviews social-cognitive and self-regulatory perspectives on involuntary job loss and subsequent job search. We begin by organizing different social-cognitive and self-regulatory perspectives along the temporal continuum of job loss and job search, and discuss the experience of job loss and its impact on the individual during subsequent job search. Using a motivational/self-regulatory frame, we then review findings related to goal generation and goal striving and outline important considerations for research design, including temporal, social, and measurement issues. Finally, we highlight the successes that have been made in the field thus far, and provide suggestions for promising future research avenues.
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van Hooft, Edwin. Self-Regulatory Perspectives in the Theory of Planned Job Search Behavior: Deliberate and Automatic Self-Regulation Strategies to Facilitate Job Seeking. Edited by Ute-Christine Klehe and Edwin van Hooft. Oxford University Press, 2016. http://dx.doi.org/10.1093/oxfordhb/9780199764921.013.31.

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Because job search often is a lengthy process accompanied by complexities, disruptions, rejections, and other adversities, job seekers need self-regulation to initiate and maintain job search behaviors for obtaining employment goals. This chapter reviews goal/intention properties (e.g., specificity, proximity, conflicts, motivation type) and skills, beliefs, strategies, and capacities (e.g., self-monitoring skills and type, trait and momentary self-control capacity, nonlimited willpower beliefs, implementation intentions, goal-shielding and goal maintenance strategies) that facilitate self-regulation and as such may moderate the relationship between job search intentions and job search behavior. For each moderator, a theoretical rationale is developed based on self-regulation theory linked to the theory of planned job search behavior, available empirical support is reviewed, and future research recommendations are provided. The importance of irrationality and nonconscious processes is discussed; examples are given of hypoegoic self-regulation strategies that reduce the need for deliberate self-regulation and conscious control by automatizing job search behaviors.
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van Hooft, Edwin. Motivation and Self-Regulation in Job Search: A Theory of Planned Job Search Behavior. Edited by Ute-Christine Klehe and Edwin van Hooft. Oxford University Press, 2016. http://dx.doi.org/10.1093/oxfordhb/9780199764921.013.010.

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Job search is a difficult and complex process that demands prolonged motivation and self-regulation. Integrating insights from generic motivation theories and the job search literature, a Theory of Planned Job Search Behavior (TPJSB) is introduced as a framework for organizing the motivational and self-regulatory predictors and mechanisms that are important in the job search process. The chapter specifically focuses on the motivation-related concepts in the TPJSB, distinguishing between global-level, contextual, and situational predictors of job search intentions and job search behavior. After describing the theoretical underpinnings, empirical support for the associations in the model is presented and reviewed, and recommendations for future research are provided. Last, the moderating role of broader context factors on the TPJSB relations is discussed.
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Genie, Tyburski, and Cavallini Donna, eds. Introduction to online legal, regulatory, & intellectual property research: Search strategies, research case study, research problems, and data source evaluations and reviews. Mason, Ohio: Thomson/Texere, 2004.

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United States. Federal Energy Regulatory Commission., ed. Records and Information Management System (RIMS): Search and retrieval user guide : version 1.0. Washington, D.C: Federal Energy Regulatory Commission, 1997.

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Klehe, Ute-Christine, and Edwin van Hooft. Introduction: What to Expect. Edited by Ute-Christine Klehe and Edwin van Hooft. Oxford University Press, 2017. http://dx.doi.org/10.1093/oxfordhb/9780199764921.013.37.

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We often associate job search with job loss, an adverse and often traumatic experience with dire consequences to individuals, their families, and societies overall. Yet job search happens far more often in better circumstances, such as when people start out on their careers, move between jobs, or follow less traditional career paths. In either case, this self-regulatory behavior is worth investigation from many different perspectives. The current handbook thus offers the first comprehensive overview of the literatures on job loss and job search, discussing the antecedents and consequences of job loss as well as different situations besides job loss that may call for an intense job search. Further, the handbook discusses the diverse theoretical and methodological perspectives from which job search has been studied, the situation of special populations, and the types of interventions that have been developed when job search proves unsuccessful in the face of unemployment.
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Book chapters on the topic "Regulatory search"

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Freyberg, Ewa. "In Search of a Perfect Regulatory System." In Growth versus Security, 260–78. London: Palgrave Macmillan UK, 2008. http://dx.doi.org/10.1057/9780230228238_13.

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Vento, Gianfranco A., and Pasquale La Ganga. "Shadow Banking and Systemic Risk: In Search of Regulatory Solutions." In Crisis, Risk and Stability in Financial Markets, 96–115. London: Palgrave Macmillan UK, 2013. http://dx.doi.org/10.1057/9781137001832_6.

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Häggblad, J., and E. Heilbronn. "Acetylcholine Release from Rat Diaphragm: A Search for Release Regulatory Mechanisms." In Advances in Behavioral Biology, 621–26. Boston, MA: Springer US, 1986. http://dx.doi.org/10.1007/978-1-4684-5194-8_60.

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Davarynejad, Mohsen, Zary Forghany, and Jan van den Berg. "Mass-Dispersed Gravitational Search Algorithm for Gene Regulatory Network Model Parameter Identification." In Lecture Notes in Computer Science, 62–72. Berlin, Heidelberg: Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-34859-4_7.

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Jana, Biswajit, Suman Mitra, and Sriyankar Acharyaa. "Reconstruction of Gene Regulatory Network Using Recurrent Neural Network Model: A Harmony Search Approach." In Advances in Intelligent Systems and Computing, 129–38. Singapore: Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-3393-4_14.

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Avgouleas, Emilios. "Financial Regulation, Behavioral Finance, and the Global Financial Crisis: In Search of a New Regulatory Model." In Lessons from the Financial Crisis, 391–99. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2011. http://dx.doi.org/10.1002/9781118266588.ch49.

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Ingersoll, Steven, Kyle Brown, Brian Ma, and Xiaojun Ren. "Quantifying the Binding and Target-Search Kinetics of Transcriptional Regulatory Factors by Live-Cell Single-Molecule Tracking." In Methods in Molecular Biology, 141–62. New York, NY: Springer US, 2022. http://dx.doi.org/10.1007/978-1-0716-2847-8_11.

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Cunha Rodrigues, Nuno. "Filling the Regulatory Gap to Address Foreign Subsidies: The EC’s Search for a Level Playing Field Within the Internal Market." In European Union and its Neighbours in a Globalized World, 197–227. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-82291-0_10.

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Nguyen, Thuy Duong. "In Search of Solutions for the Governance of the Rights of Migrant Workers in Southeast Asia: Regulatory Regionalism as a Reasonable Approach." In Global Changes and Sustainable Development in Asian Emerging Market Economies Vol. 1, 589–603. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-81435-9_40.

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Cunha Rodrigues, Nuno. "Correction to: Filling the Regulatory Gap to Address Foreign Subsidies: The EC’s Search for a Level Playing Field Within the Internal Market." In European Union and its Neighbours in a Globalized World, C1. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-82291-0_19.

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Conference papers on the topic "Regulatory search"

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Komiya, Kazuki, Nasimul Noman, and Hitoshi Iba. "The search for robust topologies of oscillatory gene regulatory networks by evolutionary computation." In the fourteenth international conference. New York, New York, USA: ACM Press, 2012. http://dx.doi.org/10.1145/2330784.2330963.

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Jafari, Mina, Vahid Sattari Naeini, and Behnam Ghavami. "The inference of predictor set in gene regulatory networks using gravitational search algorithm." In 2016 1st Conference on Swarm Intelligence and Evolutionary Computation (CSIEC). IEEE, 2016. http://dx.doi.org/10.1109/csiec.2016.7482128.

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Qiang, Bo, and Zheng-Zhi Wang. "Construction of Gene Regulatory Networks Based on Genetic Algorithm of Greedy Equivalence Search Mechanism." In 2009 3rd International Conference on Bioinformatics and Biomedical Engineering (iCBBE 2009). IEEE, 2009. http://dx.doi.org/10.1109/icbbe.2009.5162554.

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Teixeira, Lívia, Izabela Conceição, Paulo Caramelli, Marcelo Luizon, and Karina Gomes. "ALZHEIMER’S DISEASE AND TYPE 2 DIABETES MELLITUS: COMMON MIRNAS, GENES AND REGULATORY BIOLOGICAL PATHWAYS." In XIII Meeting of Researchers on Alzheimer's Disease and Related Disorders. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1980-5764.rpda066.

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Background: The increased incidence of Type 2 Diabetes Mellitus (T2DM) in the 21st century, along with the higher risk of developing Alzheimer’s disease (AD) in diabetic patients have stimulated the search for pathways that link glycemic disorders to neurodegeneration. MicroRNAs (miRNAs) are non-coding RNAs that play key roles in regulating gene expression. Objective: To identify miRNAs, genes and their regulatory pathways in common in AD and T2DM. Methods: Literature search was carried out to find miRNAs commonly expressed in AD and T2DM. MiRTarBase database was used to provide experimentally validated information on the interactions between miRNAs and their target genes. The functional enrichment of molecular pathways differentially regulated by these miRNAs was performed using EnrichR with Reactome gene set annotation. Results: We found six circulating miRNAs commonly expressed in both diseases (hsa-mir-21; hsamir-103a-1; hsa-mir-103a-2; hsa-mir-107; hsa-mir-146a and hsa-mir-144), which regulate 129 target genes. The common pathways between AD and T2DM were related to inflammatory mediators, cell death and axon formation signalling with p-adjust <10-5. Conclusion: Our study provides evidence that AD and T2DM share common pathophysiological mechanisms and regulators miRNAs, and suggests miRNAs as potential markers related to both diseases.
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Konakhina, E. S. "Regulatory support of the county and city police search criminals in the years 1860-1910." In ТЕНДЕНЦИИ РАЗВИТИЯ НАУКИ И ОБРАЗОВАНИЯ. НИЦ «Л-Журнал», 2018. http://dx.doi.org/10.18411/lj-10-2018-12.

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Tan, Yukun, Fernando B. Lima Neto, and Ulisses Braga Neto. "INFERENCE OF GENE REGULATORY NETWORKS BY MAXIMUM-LIKELIHOOD ADAPTIVE FILTERING AND DISCRETE FISH SCHOOL SEARCH." In 2018 IEEE 28th International Workshop on Machine Learning for Signal Processing (MLSP). IEEE, 2018. http://dx.doi.org/10.1109/mlsp.2018.8516967.

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Mironov, E. G., M. S. Shikhragimov, and G. V. Sozonenko. "Development of The Offline Search System for Company Internal Regulatory Documentation for Supervision of Drilling Processes." In Data Science in Oil and Gas 2021. European Association of Geoscientists & Engineers, 2021. http://dx.doi.org/10.3997/2214-4609.202156019.

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Nwankwo, Okechukwu, Michael Edem, Jennifer Muku, Chidi Ike, and Ebipador Ogionwo. "Achieving Safety at Sea – Discussing the Safety Programs Implemented by the Nigerian Upstream Petroleum Regulatory Commission." In SPE Nigeria Annual International Conference and Exhibition. SPE, 2022. http://dx.doi.org/10.2118/211954-ms.

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Abstract Over 70% of Nigeria's oil and gas reserves are in swamp and offshore environments with over 40,000 workers registered to work there. Following the signing of the Petroleum Industry Bill into law, the Nigerian Upstream Petroleum Regulatory Commission (NUPRC) as the successor agency of the Department of Petroleum Resources (DPR) is the upstream industry regulator mandated to drive several safety programs to protect people, environment, and assets through enforcement of laws and regulations. The aim of this paper is to discuss the various safety programs adopted by Commission to reduce accidents in swamp and offshore areas, in which bulk of the oil and gas operations occur. A detailed review of the programs showed that in addition to protection of people, environment and asset, safety programs drive cost savings in the industry, improves collaboration among operators, creates jobs and other economic opportunities in Nigeria. This paper will discuss in detail, the background, methodology, successes, challenges, and opportunities of some flagship safety programs of the Commission. The programs to be discussed are - Administration of Offshore Safety Permit; Implementation of Safety Case; Annual Facility Inspection and Oil Spill Contingency Plan; Risk Based Inspection; Safety and Emergency Training Center and Medical Center Accreditation and Search Rescue and Surveillance Program. This paper only gives insight into the management of safety in the Nigerian oil and gas industry and does not attempt to review the performance or effectiveness of these safety programs vis-à-vis accident statistics in the industry. The various safety programs can be adopted by regulators around the world most especially in countries with a nascent oil and gas industry.
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Hundal, Shab, and Tatyana Kauppinen. "Internationalization of family firms-challenges and opportunities in Russia." In Corporate governance: A search for emerging trends in the pandemic times. Virtus Interpress, 2021. http://dx.doi.org/10.22495/cgsetpt22.

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The family firms (FFs) play an instrumental role in the economic spectrum of the Russian economy with respect to their contribution to income, output, and employment, ceteris paribus. The FFs not only contribute the domestic business activities but also make a significant contribution to international business. Ever since the launch of the mass privatization program (MPP) in Russia during 1992–1994 numerous disruptions on the business and economic landscape of Russia have emerged, and as a result, the FFs in Russia have been experiencing several new opportunities and challenges in the international market. However, it is noticeable that corporate regulatory, and corporate governance systems do not even clearly define the FFs. The current study explores the following research objectives: first, the motivation of internationalization of family enterprises in Russia, second, their process of internationalization, and third, the problems and challenges faced by the family enterprises
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Lukovic, Vesna. "INFORMATION ASYMMETRIES IN ALGORITHMS AT DIGITAL PLATFORMS: MOTIVATIONS TO PARTICIPATE AND EU REGULATORY APPROACH." In 5th International Scientific Conference – EMAN 2021 – Economics and Management: How to Cope With Disrupted Times. Association of Economists and Managers of the Balkans, Belgrade, Serbia, 2021. http://dx.doi.org/10.31410/eman.2021.167.

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The junction of economy, law and technology is an important topic in the world that is increasingly moving online. Digital platforms “match” supply and demand by using large amounts of data and algorithms. Some digital platforms dominate travel markets because of platforms’ data and networks effects. Digital platforms in travel industry use algorithms to generate suggestions to consumers via recommendation (ranking) systems. Ranking has important implications not only for business users of digital platforms, but for consumers’ choice as well. This research explores motivations to participate in digital platforms for short-term vacation rental and it sheds light on information asymmetries in regard to algorithms generating ranking in search results. This research also briefly explores EU regulatory approach to digital platforms and looks at the latest EU legal texts in regard to fairness and transparency in ranking.
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Reports on the topic "Regulatory search"

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Morais, Bernardo, Gaizka Ormazabal, José-Luis Peydró, Mónica Roa, and Miguel Sarmiento. Forward Looking Loan Provisions: Credit Supply and Risk-Taking. Banco de la República, April 2021. http://dx.doi.org/10.32468/be.1159.

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We show corporate-level real, financial, and (bank) risk-taking effects associated with calculating loan provisions based on expected—rather than incurred—credit losses. For identification, we exploit unique features of a Colombian reform and supervisory, matched loan-level data. The regulatory change induces a dramatic increase in provisions. Banks tighten all new lending conditions, adversely affecting borrowing-firms, with stronger effects for risky-firms. Moreover, to minimize provisioning, more affected (less-capitalized) banks cut credit supply to risky-firms— SMEs with shorter credit history, less tangible assets or more defaulted loans—but engage in “search-for-yield” within regulatory constraints and increase portfolio concentration, thereby decreasing risk diversification.
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Adam, Zach, and Eran Pichersky. Degradation of Abnormal Proteins in Chloroplasts of Higher Plants. United States Department of Agriculture, August 1994. http://dx.doi.org/10.32747/1994.7568768.bard.

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In this study we attempted to get a better understanding of processes involved in the degradation of abnormal proteins i chloroplasts. To achieve this goal, we used a number of complementary approaches. We first characterized the expression of the two subunits of Clp protease. We demonstrated that both of them were expressed in chloroplasts in a constitutive fashion, but the expression of the regulatory subunit ClpC was enhanced by light. We generated a mutant the lumenal protein OEE33 which was targeted to the stroma in in vitro experiments. In the wrong compartment it was found unstable, and characterization of its degradation revealed that it was degraded by a soluble, ATP-dependent serine protease, which are also the characteristics of Clp protease. In search of other homologues of bacterial proteases, we found that chloroplasts contain a homologue of the FtsH protease. It is an ATP-dependent metallo-protease, bound to the stromal side of the thylakoid membrane, whose expression is dependent on light. The gene encodig this protease was cloned and characterized. In attempt to generate Arabidopsis mutant plants impaired in their capability to degrade abnormal chloroplast proteins, we fused the gene for mistargeted OEE33 to the streptomycin-detoxifying gene. This chimeric gene was introduced into Arabodipsis plants, to generate transformed plants. This transformants plants were sensitive to streptomycin due to the rapid turn-over of the chimeric protein. Seeds from these plants were then chemically mutagenised, and seedlings were selected for their capability to grow on streptomycin. The ability of these mutant transformants to grow on streptomycin is presumably due to stabilization of the chimeric protein. These plants will allow us in the future to identify the effected genes, which are likely to be involved in the protein degradation process.
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Granot, David, and Richard Amasino. Regulation of Senescence by Sugar Metabolism. United States Department of Agriculture, January 2003. http://dx.doi.org/10.32747/2003.7585189.bard.

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Research objectives a. Analyze transgenic plants that undergo rapid senescence due to increased expression of hexokinase. b. Determine if hexokinase-induced senescence accelerates natural senescence using senescence specific promoters that drive expression of a reporter gene (GUS) and a cytokinin producing gene (IPT - isopentyl transferase). c. Isolate and analyze plant genes that suppress sugar-induced cell death (SICD) in yeast, genes that potentially are involved in programmed cell death and senescence in plants. Background to the topic Leaf senescence is a regulated process of programmed cell death (PCD) in which metabolites are recycled to other active parts of the plant. Senescence associated genes (SAGs) are expressed throughout leaf senescence. Sugar flux and metabolism is thought to playa fundamental regulatory role in senescence. We found that transgenic tomato plants with high hexokinase activity, the initial enzymatic step of sugar (hexose) metabolism, undergo rapid leaf senescence, directly correlated with hexokinase activity. These plants provide a unique opportunity to analyze the regulatory role of sugar metabolism in senescence, and its relation to cytokinin, a senescence-inhibiting hormone. In addition, we found that sugar induces programmed cells death of yeast cells in direct correlation to hexokinase activity. We proposed to use the sugar induced cell death (SICD) to isolate Arabidopsis genes that suppress SICD. Such genes could potentially be involved in senescence induced PCD in plants. Major conclusions The promoters of Arabidopsis senescence-associated genes, SAG12 and SAGI3, are expressed in senescing tomato leaves similar to their expression in Arabidopsis leaves, indicating that these promoters are good senescence markers for tomato plants. Increased hexokinase activity accelerated senescence and induced expression of pSAG12 and pSAG13 promoters in tomato plants, suggesting that sugar regulate natural senescence via hexokinase. Expression of IPT, a cytokinin producing gene, under pSAG12 and pSAG13 promoters, delayed senescence of tomato leaves. Yet, senescence accelerated by hexokinase was epistatic over cytokinin, indicating that sugar regulation of senescence is dominant over the senescence-inhibiting hormone. A gene designated SFP1, which is similar to the major super family monosaccharide transporters, is induced during leaf senescence in Arabidopsis and may be involved in sugar transport during senescence. Accordingly, adult leaves accumulate sugars that may accelerate hexokinase activity. Light status of the entire plant affects the senescence of individual leaves. When individual leaves are darkened, senescence is induced in the covered leaves. However, whole adult plant placed in darkness show delayed senescence. In a search for Arabidopsis genes that suppress SICD we isolated 8 cDNA clones which confer partial resistance to SICD. One of the clones encodes a vesicle associated membrane protein - VAMP. This is the first evidence that vesicle trafficking might be involved in cell death. Implications Increased hexokinase activity accelerates senescence. We hypothesized that, reduced hexokinase activity may delay senescence. Preliminary experiments using a hexokinase inhibitor support this possible implication. Currently we are analyzing various practical approaches to delay leaf senescence via hexokinase inhibition. .
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Rafaeli, Ada, Russell Jurenka, and Daniel Segal. Isolation, Purification and Sequence Determination of Pheromonotropic-Receptors. United States Department of Agriculture, July 2003. http://dx.doi.org/10.32747/2003.7695850.bard.

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Moths constitute a major group of pest insects in agriculture. Pheromone blends are utilised by a variety of moth species to attract conspecific mates, which is under circadian control by the neurohormone, PBAN (pheromone-biosynthesis-activating neuropeptide). Our working hypothesis was that, since the emission of sex-pheromone is necessary to attract a mate, then failure to produce and emit pheromone is a potential strategy for manipulating adult moth behavior. The project aimed at identifying, characterising and determining the sequence of specific receptors responsible for the interaction with pheromonotropic neuropeptide/s using two related moth species: Helicoverpa armigera and H. lea as model insects. We established specific binding to a membrane protein estimated at 50 kDa in mature adult females using a photoaffinity-biotin probe for PBAN. We showed that JH is required for the up-regulation of this putative receptor protein. In vitro studies established that the binding initiates a cascade of second messengers including channel opening for calcium ions and intracellular cAMP production. Pharmacological studies (using sodium fluoride) established that the receptor is coupled to a G-protein, that is, the pheromone-biosynthesis-activating neuropeptide receptor (PBAN-R) belongs to the family of G protein-coupled receptor (GPCR)'s. We showed that PBAN-like peptides are present in Drosophila melanogaster based on bioassay and immunocytochemical data. Using the annotated genome of D. melanogaster to search for a GPCR, we found that some were similar to neuromedin U- receptors of vertebrates, which contain a similar C-terminal ending as PBAN. We established that neuromedin U does indeed induce pheromone biosynthesis and cAMP production. Using a PCR based cloning strategy and mRNA isolated from pheromone glands of H. zea, we successfully identified a gene encoding a GPCR from pheromone glands. The full-length PBAN-R was subsequently cloned and expressed in Sf9 insect cells and was shown to mobilize calcium in response to PBAN in a dose-dependent manner. The successful progress in the identification of a gene, encoding a GPCR for the neurohormone, PBAN, provides a basis for the design of a novel battery of compounds that will specifically antagonize pheromone production. Furthermore, since PBAN belongs to a family of insect neuropeptides with more than one function in different life stages, this rationale may be extended to other physiological key-regulatory processes in different insects.
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Barg, Rivka, Erich Grotewold, and Yechiam Salts. Regulation of Tomato Fruit Development by Interacting MYB Proteins. United States Department of Agriculture, January 2012. http://dx.doi.org/10.32747/2012.7592647.bard.

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Background to the topic: Early tomato fruit development is executed via extensive cell divisions followed by cell expansion concomitantly with endoreduplication. The signals involved in activating the different modes of growth during fruit development are still inadequately understood. Addressing this developmental process, we identified SlFSM1 as a gene expressed specifically during the cell-division dependent stages of fruit development. SlFSM1 is the founder of a class of small plant specific proteins containing a divergent SANT/MYB domain (Barg et al 2005). Before initiating this project, we found that low ectopic over-expression (OEX) of SlFSM1 leads to a significant decrease in the final size of the cells in mature leaves and fruits, and the outer pericarp is substantially narrower, suggesting a role in determining cell size and shape. We also found the interacting partners of the Arabidopsis homologs of FSM1 (two, belonging to the same family), and cloned their tomato single homolog, which we named SlFSB1 (Fruit SANT/MYB–Binding1). SlFSB1 is a novel plant specific single MYB-like protein, which function was unknown. The present project aimed at elucidating the function and mode of action of these two single MYB proteins in regulating tomato fruit development. The specific objectives were: 1. Functional analysis of SlFSM1 and its interacting protein SlFSB1 in relation to fruit development. 2. Identification of the SlFSM1 and/or SlFSB1 cellular targets. The plan of work included: 1) Detailed phenotypic, histological and cellular analyses of plants ectopically expressing FSM1, and plants either ectopically over-expressing or silenced for FSB1. 2) Extensive SELEX analysis, which did not reveal any specific DNA target of SlFSM1 binding, hence the originally offered ChIP analysis was omitted. 3) Genome-wide transcriptional impact of gain- and loss- of SlFSM1 and SlFSB1 function by Affymetrix microarray analyses. This part is still in progress and therefore results are not reported, 4) Search for additional candidate partners of SlFSB1 revealed SlMYBI to be an alternative partner of FSB1, and 5) Study of the physical basis of the interaction between SlFSM1 and SlFSB1 and between FSB1 and MYBI. Major conclusions, solutions, achievements: We established that FSM1 negatively affects cell expansion, particularly of those cells with the highest potential to expand, such as the ones residing inner to the vascular bundles in the fruit pericarp. On the other hand, FSB1 which is expressed throughout fruit development acts as a positive regulator of cell expansion. It was also established that besides interacting with FSM1, FSB1 interacts also with the transcription factor MYBI, and that the formation of the FSB1-MYBI complex is competed by FSM1, which recognizes in FSB1 the same region as MYBI does. Based on these findings a model was developed explaining the role of this novel network of the three different MYB containing proteins FSM1/FSB1/MYBI in the control of tomato cell expansion, particularly during fruit development. In short, during early stages of fruit development (Phase II), the formation of the FSM1-FSB1 complex serves to restrict the expansion of the cells with the greatest expansion potential, those non-dividing cells residing in the inner mesocarp layers of the pericarp. Alternatively, during growth phase III, after transcription of FSM1 sharply declines, FSB1, possibly through complexing with the transcription factor MYBI serves as a positive regulator of the differential cell expansion which drives fruit enlargement during this phase. Additionally, a novel mechanism was revealed by which competing MYB-MYB interactions could participate in the control of gene expression. Implications, both scientific and agricultural: The demonstrated role of the FSM1/FSB1/MYBI complex in controlling differential cell growth in the developing tomato fruit highlights potential exploitations of these genes for improving fruit quality characteristics. Modulation of expression of these genes or their paralogs in other organs could serve to modify leaf and canopy architecture in various crops.
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