Dissertations / Theses on the topic 'Regulatory genes'
Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles
Consult the top 50 dissertations / theses for your research on the topic 'Regulatory genes.'
Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.
You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.
Browse dissertations / theses on a wide variety of disciplines and organise your bibliography correctly.
Chen, Hairong [Verfasser]. "Functional analysis of candidate regulatory genes in regulatory T cells / Hairong Chen." Hannover : Bibliothek der Tierärztlichen Hochschule Hannover, 2013. http://d-nb.info/1032432594/34.
Full textHodgkinson, Lisa Marie. "Matrix regulatory genes in the human lens." Thesis, University of East Anglia, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.490590.
Full textColl-Lladó, Clara. "Evolution of muscle regulatory genes in chordates." Thesis, University of St Andrews, 2016. http://hdl.handle.net/10023/16136.
Full textUprety, Bhawana. "Transcriptional Regulatory Mechanisms of Ribosomal Protein Genes." OpenSIUC, 2015. https://opensiuc.lib.siu.edu/dissertations/1080.
Full textChan, Ping-kei. "The study of the regulatory elements of the human [beta]-globin gene." Click to view the E-thesis via HKUTO, 2005. http://sunzi.lib.hku.hk/hkuto/record/B31999062.
Full textChan, Ping-kei, and 陳炳基. "The study of the regulatory elements of the human {221}-globin gene." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2005. http://hub.hku.hk/bib/B31999062.
Full textNora, Fabiana Roos. "Interactions between regulatory genes required for meristem development." Thesis, University of East Anglia, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.432435.
Full textZhang, Yongquan. "Regulatory elements controlling the expression of OR37 genes." [S.l. : s.n.], 2007. http://nbn-resolving.de/urn:nbn:de:bsz:100-opus-2272.
Full textAagaard, Jan Erik. "Evolution of floral regulatory genes in the Lamiales /." view abstract or download file of text, 2004. http://wwwlib.umi.com/cr/uoregon/fullcit?p3136400.
Full textTypescript. Includes vita and abstract. Includes bibliographical references (leaves 96-104). Also available for download via the World Wide Web; free to University of Oregon users.
Guo, Xiumei. "Regulatory and functional study of human cytoglobin." Click to view the E-thesis via HKUTO, 2007. http://sunzi.lib.hku.hk/hkuto/record/B3860145X.
Full textChen, Di. "Regulatory pathways controlling larval development in caenorhabditis elegans." Free to MU Campus, others may purchase, 2004. http://wwwlib.umi.com/cr/mo/fullcit?p3144405.
Full textTay, Yii Van. "Fates of genes after duplication : sublocalization and regulatory neofunctionalization." Thesis, University of British Columbia, 2013. http://hdl.handle.net/2429/44264.
Full textKenyon, Julie R. "An analysis of upstream regulatory regions of retinal genes." Thesis, University of Oxford, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.268141.
Full textCarter, D. P. F. "Long-range functional interactions between genes and regulatory elements." Thesis, University of Cambridge, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.597329.
Full textOudelaar, A. Marieke. "The three-dimensional regulatory landscapes of the globin genes." Thesis, University of Oxford, 2018. http://ora.ox.ac.uk/objects/uuid:6cd793fe-b28a-4d98-a588-b6eec5dfa416.
Full textFurchtgott, Leon A. "Simultaneous Inference of Cell Types, Lineage Trees, and Regulatory Genes From Gene Expression Data." Thesis, Harvard University, 2016. http://nrs.harvard.edu/urn-3:HUL.InstRepos:33493563.
Full textBiophysics
Dash, Bhagirathi. "Molecular cloning and characterization of important stress and redox regulatory genes from Hydra vulgaris." Texas A&M University, 2005. http://hdl.handle.net/1969.1/4994.
Full textBorba, Ana Rita Andrade. "Transcriptional regulatory mechanisms controlling key genes involved in C4 photosynthesis in maize." Doctoral thesis, Universidade Nova de Lisboa, Instituto de Tecnologia Química e Biológica António Xavier, 2019. http://hdl.handle.net/10362/94108.
Full textN/A
Moses, Daniel. "Regulatory Elements, Protein Function and Evolution of the Actinodin Genes." Thèse, Université d'Ottawa / University of Ottawa, 2013. http://hdl.handle.net/10393/26216.
Full textKetterling, Matthew Gene. "Quantitative analysis of CIS-regulatory sequences in genes of arabidopsis." [Gainesville, Fla.] : University of Florida, 2003. http://purl.fcla.edu/fcla/etd/UFE0001266.
Full textGuo, Xiumei, and 郭秀梅. "Regulatory and functional study of human cytoglobin." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2007. http://hub.hku.hk/bib/B3860145X.
Full textZhang, Wei, and 张伟. "Characterization of distal and proximal regulatory elements of the human neuroglobin gene." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2011. http://hub.hku.hk/bib/B47147568.
Full textGarrett, Christine. "Functional mapping of pea legumin upstream regulatory elements using TI plasmid vectors." Thesis, Durham University, 1991. http://etheses.dur.ac.uk/6041/.
Full textPati, Amrita. "Modeling and Analysis of Regulatory Elements in Arabidopsis thaliana from Annotated Genomes and Gene Expression Data." Thesis, Virginia Tech, 2005. http://hdl.handle.net/10919/44132.
Full textMaster of Science
Webber, Aaron. "Transcriptional co-regulation of microRNAs and protein-coding genes." Thesis, University of Manchester, 2013. https://www.research.manchester.ac.uk/portal/en/theses/transcriptional-coregulation-of-micrornas-and-proteincoding-genes(f5b601b2-33f3-4608-9ae8-b7d5a0c6beaf).html.
Full textSmeds, Johanna. "Role of the CDKN2A and related cell cycle regulatory genes in melanoma and other human cancers /." Stockholm, 2002. http://diss.kib.ki.se/2002/91-7349-105-5/.
Full textSvingen, Terje, and n/a. "Hox Transcription Factors: Their Involvement in Human Cancer Cells and In Vitro Functional Specificity." Griffith University. School of Biomolecular and Biomedical Science, 2005. http://www4.gu.edu.au:8080/adt-root/public/adt-QGU20050830.135356.
Full textSvingen, Terje. "Hox Transcription Factors: Their Involvement in Human Cancer Cells and In Vitro Functional Specificity." Thesis, Griffith University, 2005. http://hdl.handle.net/10072/365774.
Full textThesis (PhD Doctorate)
Doctor of Philosophy (PhD)
School of Biomolecular and Physical Sciences
Full Text
Smart, James. "A partial characterization of three photosynthetic regulatory genes in Rhodobacter capsulatus." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2001. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/NQ61681.pdf.
Full textLim, Jeong-Eun. "Regulatory genetic variants in mental illness focus on serotonin-related genes /." Columbus, Ohio : Ohio State University, 2007. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1196198735.
Full textGriffiths, Marcus. "Identifying wheat root traits and regulatory genes for nitrogen uptake efficiency." Thesis, University of Nottingham, 2018. http://eprints.nottingham.ac.uk/48611/.
Full textBahirwani, Vishal. "Exploring transcription patterns and regulatory motifs in Arabidopsis thaliana." Thesis, Manhattan, Kan. : Kansas State University, 2010. http://hdl.handle.net/2097/4194.
Full textBasford, Joshua E. "Colinear Expression of the Mouse HoxB Cluster: Potential Regulatory Role of Histone H4 Acetylation." University of Cincinnati / OhioLINK, 2001. http://rave.ohiolink.edu/etdc/view?acc_num=ucin997988435.
Full textMejías, Luque Raquel. "Regulatory effects of pro-inflammatory cytokines on genes associated with gastric carcinogenesis." Doctoral thesis, Universitat Pompeu Fabra, 2009. http://hdl.handle.net/10803/7156.
Full textLa gastritis crònica produïda per la infecció per Helicobacter pylori és un dels principals determinants en la patogènesi del càncer gàstric, i comporta nivells elevats de citoquines proinflamatòries com TNF-α, IL-1β o IL-6, que poden regular l'expressió de gens implicats en la transformació neoplàsica gàstrica. Vam analitzar l'efecte de citoquines proinflamatòries en l'expressió de glicosiltransferases i antígens Lewis en cèl·lules de càncer gàstric va ser analitzat i vam observar que el tractament d'aquestes cèl·lules amb IL-1β augmentava l'expressió d'antígens Lewis de tipus 2. A més, vam observar que tumors gàstrics amb inflamació crònica presentaven nivells més elevats d'estructures glicosídiques de tipus 2, suggerint que determinades glicosiltransferases podrien estar regulades per la inflamació.
Els adenocarcinomes gàstrics de tipus intestinal s'originen a partir d'una sèrie successiva de lesions precanceroses que porten a una transdiferenciació intestinal de la mucosa gàstrica. En aquest procés s'activa l'expressió de diferents gens intestinals a les cèl·lules gàstriques, com és el cas dels gens de les mucines intestinals MUC2 i MUC4 i del factor de transcripció intestinal CDX2. Nosaltres vam estudiar l'efecte de citoquines inflamatòries i de les seves vies de senyalització associades en l'expressió d'aquests gens va ser estudiat. El primer que vam constatar va ser que IL-6 regulava l'expressió de MUC4 a través de la via de gp130/STAT3 a línies cel·lulars de càncer gàstric, mentre que l'expressió de MUC2 era induïda per TNF-α a través de la via de senyalització de NF-κB. A més, vam observar que l'expressió de CDX2 no era regulada per citoquines inflamatòries. Finalment, vam trobar que les diferències en l'expressió de les mucines intestinals MUC2 i MUC4 a tumors gàstrics podien ser explicades per diferències en el tipus d'inflamació predominant.
De tots aquests resultats podem concloure que la inflamació i les vies de senyalització associades modulen l'expressió de gens associats a la carcinogènesi gàstrica.
In the gastric carcinogenetic process the specific expression pattern of glycosyltransferases and Lewis antigens displayed by the normal gastric mucosa is lost. We detected that changes in the expression of Lewis antigens induced by the transfection of FUT1 cDNA in HT-29/M3 cells determined a less invasive and metastatic phenotype.
Chronic gastritis caused by H. pylori infection is a major determinant in the pathogenesis of gastric cancer, and present increased levels of the pro-inflammatory cytokines TNF-α, IL-1β and IL-6, which can regulate the expression of genes involved in the gastric neoplastic transformation. We analysed the effect of pro-inflammatory cytokines on the expression of glycosyltransferases and Lewis antigens in gastric cancer cells. IL-1β treatment increased the expression of type 2 Lewis antigens, and, in addition, we observed that gastric tumours with chronic inflammation displayed increased levels of type 2 glycan structures, suggesting that specific glycosyltransferases may be regulated by inflammation.
Intestinal-type gastric adenocarcinomas develop from successive pre-cancerous lesions that lead to an intestinal transdifferentiation of the gastric mucosa. In this process many intestinal genes are activated in gastric cells, such as the intestinal mucin MUC2 and MUC4 genes and the transcription factor CDX2. We studied the effect of pro-inflammatory cytokines and their associated signalling pathways on the expression of these genes. IL-6 regulated the expression of MUC4 through the gp130/STAT3 signalling pathway in gastric cancer cell lines, while MUC2 expression was induced by TNF-α through the NF-κB signalling pathway. No effects on CDX2 expression were observed after cytokine treatment in gastric tumour cells. Finally, we found that the differences observed in the expression of the intestinal mucins MUC2 and MUC4 in gastric tumours could be explained by differences in the predominant type of inflammation present in gastric adenocarcinomas.
In conclusion, our results suggest that inflammation and its associated signalling pathways modulate the expression of genes associated with gastric carcinogenesis.
Lundmark, Frida. "Genetic analysis of IL7R and other immune-regulatory genes in multiple sclerosis /." Stockholm : Karolinska institutet, 2007. http://diss.kib.ki.se/2007/978-91-7357-278-1/.
Full textSun, Lei. "Biodiversity of transporter and regulatory genes involved in dimethylsulphoniopropionate catabolism in bacteria." Thesis, University of East Anglia, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.514337.
Full textBitton, Danny Asher. "Discovery of Novel Protein Coding Genes and Antisense Regulatory Transcripts in Eukaryotes." Thesis, University of Manchester, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.532201.
Full textAlcock, Rachael A. "Role of cell death regulatory genes and radiation response in pancreatic adenocarcinomas." Thesis, University of Central Lancashire, 2002. http://clok.uclan.ac.uk/1745/.
Full textMootien, Saraspadee. "New pleiotropic regulatory genes for antibiotic production in Streptomyces coelicolor A3(2)." Thesis, University of East Anglia, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.327543.
Full textBlacha, Anna Maria. "Investigating the role of regulatory genes in heterosis for superior growth and biomass production in Arabidopsis thaliana." Phd thesis, Universität Potsdam, 2009. http://opus.kobv.de/ubp/volltexte/2010/4614/.
Full text„Heterosis“ ist ein in der Genetik und der Züchtung verwendeter Begriff, der die Hybridwüchsigkeit oder die Überlegenheit der Hybriden über ihre Eltern in Bezug auf Eigenschaften wie Größe, Wachstumsrate, Biomasse, Fruchtbarkeit, Ertrag, Nährstoffgehalt, Widerstand gegen Krankheiten oder Toleranz in Bezug auf biotischen oder abiotischen Stress bezeichnet. Um Hybriden zu erzeugen, werden aus zwei verschiedenen Inzuchtlinien (reine Linien) bestehende Elternpflanzen, welche die gewünschten Eigenschaften besitzen, miteinander gekreuzt. Der stärkste Heterosiseffekt wird in der ersten Kreuzungsgeneration (F1) beobachtet. Heterosis wird in Pflanzen- und Tierzuchtprogrammen schon seit mindestens 90 Jahren genutzt. So beruhte zum Ende des 20. Jahrhunderts 65% der weltweiten Maisproduktion auf Hybridzüchtung. Es wird angenommen, dass ein Verständnis der molekularen Grundlagen der Heterosis die Schaffung neuer, überlegener Genotypen erlaubt, die dann direkt als F1-Hybriden verwendet, oder als Grundlage für zukünftige Zucht- und Selektionsprogramme dienen können. Zwei ausgewählte Akzessionen der Modellpflanze Arabidopsis thaliana (Ackerschmalwand) wurden miteinander gekreuzt, um Hybriden zu erzeugen. Verglichen mit dem durchschnittlichen Gewicht ihren beiden Elternlinien zeigten diese eine 60-80%ige Zunahme an Biomasse. Diese Doktorarbeit befasst sich damit, die Rolle ausgewählter, regulatorischer Gene und ihre mögliche Schlüsselrolle bei der Heterosis zu untersuchen. Im ersten Teil der Arbeit wurde anhand der Gehaltsbestimmung ausgewählter Stoffwechselprodukte und Wachstumsbeobachtungen bei den Eltern und Hybriden das günstigste Entwicklungsstadium für diese Heterosisstudie bestimmt. In diesem Entwicklungsstadium wurden ungefähr 60 regulatorische Gene (d.h. Expressionsunterschiede zwischen Hybriden und Elternlinien) als Kandidaten identifiziert. Ein Großteil dieser Kandidaten waren Transkriptionsfaktoren, also Gene, die die Expression anderer Gene regulieren. Die nachfolgende Expressionsanalyse dieser Kandidatengene in Biomasse-Heterosis Hybriden anderer Arabidopsis Akzessionen zeigte bei einem Teil dieser Gene Expressionsunterschiede, die ihre Bedeutung bei der Heterosis betonen. Darüber hinaus wurde ein Teil dieser regulatorischen Kandidatengene innerhalb von DNS-Regionen gefunden, die eng mit Biomasse- oder Wachstumsheterosis in Verbindung stehen, und somit ihre Wichtigkeit in Bezug auf Heterosis unterstreichen. Weitergehende Analysen um die Rolle dieser ausgewählten regulatorischen Kandidatengene bei der Heterosis aufzuklären, waren nicht aussagekräftig genug, um ihre Rolle bei der Heterosis zu bestätigen. In der Doktorarbeit wird die Notwendigkeit neue Wege zur Aufklärung der Heterosis zu finden, diskutiert. Zusammenfassend gibt diese Doktorarbeit einen Einblick über Studien der molekularen Mechanismen, die der Heterosis zugrunde liegen. Diese Arbeit zeigt, dass obwohl Heterosis bereits seit mehr als hundert Jahren studiert wird, weitere Untersuchungen zur Aufklärung dieses Phänomens notwendig sind.
Ghosh, Priyanjali. "Investigating the Gene Regulatory Network Underlying Caudal Hindbrain Specification in Embryonic Zebrafish." eScholarship@UMMS, 2018. https://escholarship.umassmed.edu/gsbs_diss/979.
Full textRahrami, Ahmad Reza. "Characterisation and manipulation of a plant proteasome subunit gene." Thesis, University of Sheffield, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.340216.
Full textEngström, Pär. "Gene complexes and regulatory domains in metazoan genomes /." Stockholm : Karolinska institutet, 2007. http://diss.kib.ki.se/2007/978-91-7357-361-0/.
Full textRamdayal, Kavisha. "Incidence and Regulatory Implications of Single Nucleotide Polymorphisms among Established Ovarian Cancer Genes." Thesis, Online access, 2009. http://etd.uwc.ac.za/usrfiles/modules/etd/docs/etd_gen8Srv25Nme4_5111_1277754725.pdf.
Full textThuraisingam, Thusanth. "Macrophage regulatory genes Nramp1 and MK2 : implication in inflammation and cutaneous wound healing." Thesis, McGill University, 2007. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=111902.
Full textHayesmoore, Jesse B. G. "Investigation of cis-regulatory variation in candidate genes for psychiatric and neurodegenerative disease." Thesis, Cardiff University, 2009. http://orca.cf.ac.uk/55874/.
Full textColeman, Heather. "Analyses of coding and regulatory sequences for delayed-early genes of herpesvirus saimiri." Thesis, Open University, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.303950.
Full textDelaney, S. J. "Cis-acting regulatory elements of the larval serum protein-1 genes of Drosopila." Thesis, Imperial College London, 1987. http://hdl.handle.net/10044/1/38282.
Full textPerrine, Kimberly Gayle. "Genetic analysis of regulatory and structural genes of nitrogen metabolism in Neurospora crassa /." The Ohio State University, 1985. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487262513407313.
Full textBali, Anish. "Cell cycle regulatory genes as markers of outcome in serious epithelial ovarian cancer." Thesis, University of Edinburgh, 2002. http://hdl.handle.net/1842/23173.
Full text