Academic literature on the topic 'Regulatory functions'

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Journal articles on the topic "Regulatory functions"

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Vasiliev, J. M., and V. I. Samoylov. "Regulatory functions of microtubules." Biochemistry (Moscow) 78, no. 1 (January 2013): 37–40. http://dx.doi.org/10.1134/s0006297913010045.

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Means, Anthony R., Mark F. A. VanBerkum, Indrani Bagchi, Kun Ping Lu, and Colin D. Rasmussen. "Regulatory functions of calmodulin." Pharmacology & Therapeutics 50, no. 2 (January 1991): 255–70. http://dx.doi.org/10.1016/0163-7258(91)90017-g.

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Stampfel, Gerald, Tomáš Kazmar, Olga Frank, Sebastian Wienerroither, Franziska Reiter, and Alexander Stark. "Transcriptional regulators form diverse groups with context-dependent regulatory functions." Nature 528, no. 7580 (November 9, 2015): 147–51. http://dx.doi.org/10.1038/nature15545.

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Murakami, Makoto, Yoshihito Nakatani, Gen-ichi Atsumi, Keizo Inoue, and Ichiro Kudo. "Regulatory Functions of Phospholipase A2." Critical Reviews™ in Immunology 17, no. 3-4 (1997): 225–83. http://dx.doi.org/10.1615/critrevimmunol.v17.i3-4.10.

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Murakami, Makoto, Yoshihito Nakatani, Gen-ichi Atsumi, Keizo Inoue, and Ichiro Kudo. "Regulatory Functions of Phospholipase A2." Critical Reviews in Immunology 37, no. 2-6 (2017): 121–79. http://dx.doi.org/10.1615/critrevimmunol.v37.i2-6.20.

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Grzybowska, Ewa A., Anna Wilczynska, and Janusz A. Siedlecki. "Regulatory Functions of 3′UTRs." Biochemical and Biophysical Research Communications 288, no. 2 (October 2001): 291–95. http://dx.doi.org/10.1006/bbrc.2001.5738.

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Vakhitov, T. Ya, and L. N. Petrov. "Regulatory functions of bacterial exometabolites." Microbiology 75, no. 4 (July 2006): 415–19. http://dx.doi.org/10.1134/s0026261706040084.

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Barczyk-Kahlert, K. "SP0160 Regulatory Functions of Macrophages." Annals of the Rheumatic Diseases 73, Suppl 2 (June 2014): 43.1–43. http://dx.doi.org/10.1136/annrheumdis-2014-eular.6186.

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Fillatreau, Simon. "Regulatory functions of B cells and regulatory plasma cells." Biomedical Journal 42, no. 4 (August 2019): 233–42. http://dx.doi.org/10.1016/j.bj.2019.05.008.

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Bowen, Frances, and Panos Panagiotopoulos. "Regulatory roles and functions in information-based regulation: a systematic review." International Review of Administrative Sciences 86, no. 2 (July 16, 2018): 203–21. http://dx.doi.org/10.1177/0020852318778775.

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Information-based regulation occurs when regulators use information to drive changes in behaviours in order to achieve public policy objectives. Information-based regulation has emerged as an alternative way to regulate firms compared with more traditional direct command-and-control and market-based policy instruments within the contemporary regulatory state. Despite growing international interest, challenges remain in understanding the roles for regulators in information-based regulation, the functions of regulators in shaping and leveraging information flows, and the administrative capacities required to fulfil them. Based on a systematic review methodology, this article synthesises the findings of 130 peer-reviewed articles in the environmental, energy and food policy areas. It develops a typology of functions for regulators and outlines the new administrative capacities required in the contemporary regulatory state, particularly in standard setting, assurance and intermediation, and smart data management. Points for practitioners Regulation by information is becoming popular in many part of the world beyond its original genesis in the US and other developed countries. The design and implementation of such schemes creates new challenges for regulators. Our review integrates relevant research in three policy areas (environment, food and energy) and develops a new typology of functions performed by regulators. The article is the first to discuss how the roles and functions of regulators need to change in the contemporary information and regulatory environment. It also emphasises the importance of regulatory involvement in information-based regulation, which has traditionally been seen as a deregulatory approach.
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Dissertations / Theses on the topic "Regulatory functions"

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Liu, Ruisheng. "Regulatory Functions of the Juxtaglomerular Apparatus." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2002. http://publications.uu.se/theses/91-554-5199-3/.

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Hamilton, Alexander Brian. "Immune functions & mechanisms of regulatory T cells." Thesis, University of Cambridge, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.648192.

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Smith, Richard LeRoy. "Cis-regulatory Sequence and Co-regulatory Transcription Factor Functions in ERα-Mediated Transcriptional Repression." BYU ScholarsArchive, 2009. https://scholarsarchive.byu.edu/etd/2261.

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Estrogens exert numerous actions throughout the human body, targeting healthy tissue while also enhancing the proliferative capacity of breast cancers. Estrogen signaling is mediated by the estrogen receptor (ER), which binds DNA and ultimately affects the expression of adjacent genes. Current understanding of ER-mediated transcriptional regulation is mostly limited to genes whose transcript levels increase following estrogen exposure, though recent studies demonstrate that direct down-regulation of estrogen-responsive genes is also a significant feature of ER action. We hypothesized that differences in cis-regulatory DNA was a factor in determining target gene expression and performed computational and experimental studies to test this hypothesis. From our in silico analyses, we show that the binding motifs for certain transcription factors are enriched in cis-regulatory sequences adjacent to repressed target genes compared to induced target genes, including the motif for RUNX1. In silico analyses were tested experimentally using dual luciferase reporter assays, which indicate that several ER binding sites are estrogen responsive. Mutagenesis of transcription factor motifs (for ER and RUNX1) reduced the response of reporter gene. Further experiments demonstrated that co-recruitment of ER and RUNX1 is necessary for repression of gene expression at some target genes. These findings highlight a novel interaction between ER and RUNX1 and their role in transcriptional repression in breast cancer.
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Fristedt, Rikard. "Regulatory Functions of Protein Phosphorylation in Plant Photosynthetic Membranes." Doctoral thesis, Linköpings universitet, Cellbiologi, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-62303.

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Oxygenic photosynthesis is the process in plants, algae and cyanobacteria which converts light energy from the sun into carbohydrates and at the same time produces oxygen from water. Both carbohydrates and oxygen are essential to sustain life on earth. Sunlight is thus a necessity for life, but it can also cause severe problems for photosynthetic organisms, which have evolved several remarkable acclimation systems to cope with light fluctuations in the environment. In higher plants the light driven reactions of photosynthesis proceed in the chloroplast thylakoid membranes highly organized into stacked regions of grana and interconnecting stroma  lamellae. The grana structure is thought to provide functional benefits in the processes of acclimation of the photosynthetic apparatus, particularly in the quality control of photosystem II (PSII) were photodamaged PSII is repaired in a stepwise manner. These processes in the thylakoid membranes were suggested to be regulated by reversible phosphorylation of several proteins in PSII and in its light harvesting antennae complexes (LHCII). Two thylakoid protein kinases, called STN8 and STN7, have been previously identified as responsible for the phosphorylation of PSII and LHCII, respectively. However, molecular mechanisms and the exact functions of these protein phosphorylation events remained largely unknown. In this thesis research I have demonstrated that the PSII protein phosphorylation is needed for the maintenance of the thylakoid structure in Arabidopsis thaliana chloroplasts. A big part of the work on characterization of proteins and their phosphorylation has been done using novel mass spectrometry techniques, and we further developed a label-free method for quantitative studies of protein phosphorylation. The phosphorylation of PSII proteins was found to be diurnal regulated and required for maintenance of the cation-dependent functional stacking of the thylakoid membranes. This phosphorylation was further shown to be important for the regulated turnover of the D1 protein of PSII. Phosphorylation of the plant specific TSP9 protein was found to be dependent on STN7 kinase, and plants deficient in TSP9 showed reduced ability to perform the photosynthetic state transitions and to execute thermal dissipation of excess light energy under high light conditions. I also accomplished characterization of the protein phosphorylation in thylakoids from Arabidopsis plants subjected to high light treatment and discovered STN7-dependent phosphorylation of the antenna protein CP29 required for the adaptive disassembly of PSII supercomplexes in conditions of high light stress.
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Yang, Pei-Jung. "Regulatory functions during the transition to new school environments." Thesis, University of Cambridge, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.609242.

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Salerno, Paolo. "«Energy Regulatory Commission»: Character and functions after energy reform." Pontificia Universidad Católica del Perú, 2016. http://repositorio.pucp.edu.pe/index/handle/123456789/115445.

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The Mexican energy reform in December 2013 has represented a radical change in the structure of the sector, which has grown from a public monopoly to a competitive market. This article aims to analyze the attributions and the legal and administrative nature which has be granted to the Energy Regulatory Commission (CRE) after the normative change that will play a key role in the correct implementation thereof. The nodal problem is to confirm if the CRE has being given the correct legal instruments to develop its function autonomously and transparently.
La reforma energética mexicana de diciembre de 2013 ha representado un cambio radical en la estructuración del sector, el cual ha pasado de ser un monopolio público a un mercado de libre competencia. El presente artículo tiene como objetivo analizar las atribuciones y la naturaleza jurídico administrativa que se ha concedido a la Comisión Reguladora de Energía (CRE) tras el cambio normativo, dado que este, en calidad de organismo regulador del sector, tendrá un rol fundamental en la correcta implementación de la misma. El problema nodal de la cuestión reside en corroborar si se ha dotado a la CRE de los correctos instrumentos jurídicospara desenvolver su función de forma autónoma y transparente.
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Vučićević, Dubravka [Verfasser]. "Diverse regulatory functions of long non-coding RNAs / Dubravka Vučićević." Berlin : Freie Universität Berlin, 2017. http://d-nb.info/1137509899/34.

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Shi, Xinhui. "Regulatory Functions of ZmMYB31 and ZmMYB42 in Maize Phenylpropanoid Pathway." University of Toledo / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1302295047.

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Tilley, Gareth John. "Electrochemical investigations into iron-sulfur cluster containing proteins." Thesis, University of Oxford, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.365300.

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Liu, Chaohong. "Regulatory functions of the actin cytoskeleton in B cell receptor signaling." Thesis, University of Maryland, College Park, 2013. http://pqdtopen.proquest.com/#viewpdf?dispub=3599621.

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The binding of antigen (Ag) to the B cell receptor (BCR) induces the activation of intracellular signaling and the reorganization of the actin cytoskeleton. However, the function of actin reorganization and the mechanisms by which BCR signaling and actin reorganization is coupled have not been well studied. This thesis has investigated how BCR signaling regulates actin reorganization and how actin remodeling in turn influences BCR signalig. My studies show that the key stimulatory signaling molecule of the BCR, Bruton's tyrosine kinase (Btk), is critical for actin polymerization at the activation surface and BCR clustering and B cell spreading, events that are essential for signaling initiation and amplification. The key inhibitory signaling molecule, SH2-containing phosphatidylinositol-5 phasphatase (SHIP-1), is important for removal of F-actin from the activation surface, and actin-mediated B cell contraction and the formation of BCR central clusters. SHIP-1 suppresses actin polymerization by inhibiting Btk-dependent activation of Wiskott-Aldrich syndrome protein (WASP). These results suggest that BCR signaling can regulate B cell morphology and surface BCR clustering via modulationg actin dynamics. To understand the roles of actin reorganization in BCR signaling, I investigated the effects of gene knockout of the two actin regulators, WASP and its homolog, neuronal (N)-WASP. My results show that both WASP and N-WASP are required for optimal BCR clustering, B cell spreading, and BCR signaling, but they play distinct roles. WASP promotes actin polymerization, B cell spreading, BCR clustering, and signaling amplification, and N-WASP inhibits actin polymerization at the activation surface and promotes B cell contraction, BCR central cluster formation, and signaling attenuation. Importantly, B cell-specific N-WASP knockout causes increases in the levels of autoantibody. In addition, WASP and N-WASP negatively regulate each other, compete for Arp2/3, and are inversely regulated by Btk and SHIP-1. Taken together, these results demonstrate that the balance of stimulatory and inhibitory BCR signaling controls actin dynamics and organization through regulating the activities of WASP and N-WASP. Actin remodeling in turn amplifies BCR signaling activation or down regulation by modulating B cell morphlogy and the organization of surface BCRs.This research reveals a bidrectional feedback loop between BCR signaling and the actin cytoskeleton.

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Books on the topic "Regulatory functions"

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Moss, Joel, and Peter Zahradka, eds. ADP-Ribosylation: Metabolic Effects and Regulatory Functions. Boston, MA: Springer US, 1994. http://dx.doi.org/10.1007/978-1-4615-2614-8.

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Bock, Gregory, and Jamie Goode, eds. Generation and Effector Functions of Regulatory Lymphocytes. Chichester, UK: John Wiley & Sons, Ltd, 2003. http://dx.doi.org/10.1002/0470871628.

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Reza, Sadrel. Privatizing industrial regulatory functions in Bangladesh: An operational strategy. Dhaka, Bangladesh: University Press Ltd., 1994.

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Eden, Laurence. Investigation on RNA transport and regulatory functions from human adenovirus 5. [s.l.]: typescript, 1994.

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Shinozuka, Masanobu. Power spectral density functions compatible with NRC regulatory guide 1.60 response spectra. Washington, DC: Division of Engineering, Division of Reactor Accident Analysis, Office of Nuclear Regulatory Research, U.S. Nuclear Regulatory Commission, 1988.

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U.S. Nuclear Regulatory Commission. Office of Inspector General. The United States Nuclear Regulatory Commission: The Office of the Inspector : history, mission, staff and organization, functions and products. [Washington, D.C.?]: U.S. Nuclear Regulatory Commission, 1997.

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Office, Great Britain Cabinet. How to improve local authority regulatory services: A guide to Charter Mark for enforcement functions. London: Cabinet Office, 1998.

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Office, New Zealand Audit. Report of the Controller and Auditor-General, Tumuaki o te Mana Arotake: Contracting out local authority regulatory functions. [Wellington: Office of the Controller and Auditor-General, 1999.

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Ignacio, Montero, ed. Current research trends in private speech: Proceedings of the First International Symposium on Self-regulatory Functions of Language. Madrid: UAM Ediciones, 2007.

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Sirotkin, Alexander V. Regulators of ovarian functions. Hauppauge, N.Y: Nova Science Publishers, 2010.

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Book chapters on the topic "Regulatory functions"

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Levy, D. N., Y. Refaeli, and D. B. Weiner. "The vpr Regulatory Gene of HIV." In Transacting Functions of Human Retroviruses, 209–36. Berlin, Heidelberg: Springer Berlin Heidelberg, 1995. http://dx.doi.org/10.1007/978-3-642-78929-8_11.

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Kudo, Ichiro, and Makoto Murakami. "Regulatory Functions of Prostaglandin E2 Synthases." In Advances in Experimental Medicine and Biology, 103–6. Boston, MA: Springer US, 2003. http://dx.doi.org/10.1007/978-1-4419-9194-2_20.

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van Hinsbergh, Victor W. M. "Regulatory functions of the coronary endothelium." In Lipid Metabolism in the Healthy and Disease Heart, 163–69. Boston, MA: Springer US, 1992. http://dx.doi.org/10.1007/978-1-4615-3514-0_23.

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Burd, Christopher G., and Ruth N. Collins. "Functions of Rab GTPases in organelle biogenesis." In Regulatory Mechanisms of Intracellular Membrane Transport, 65–88. Berlin, Heidelberg: Springer Berlin Heidelberg, 2004. http://dx.doi.org/10.1007/b97781.

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Černecký, Ján, Jana Špulerová, Viktória Ďuricová, Peter Mederly, Martin Jančovič, Juraj Hreško, and Matej Močko. "Regulatory Ecosystem Services and Supporting Ecosystem Functions." In A Catalogue of Ecosystem Services in Slovakia, 91–184. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-46508-7_4.

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Sugimura, Takashi, and Masanao Miwa. "Poly(ADP-ribose): Historical perspective." In ADP-Ribosylation: Metabolic Effects and Regulatory Functions, 5–12. Boston, MA: Springer US, 1994. http://dx.doi.org/10.1007/978-1-4615-2614-8_1.

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Smulson, Mark E. "Poly(ADP-ribose) polymerase gene on chromosome 1q: Early role in differentiation linked replication; gene on human chromosome 13q: Marker of carcinogenesis." In ADP-Ribosylation: Metabolic Effects and Regulatory Functions, 77–84. Boston, MA: Springer US, 1994. http://dx.doi.org/10.1007/978-1-4615-2614-8_10.

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Bürkle, Alexander, Marcus Müller, Ivo Wolf, and Jan-Heiner Küpper. "Poly(ADP-ribose) polymerase activity in intact or permeabilized leukocytes from mammalian species of different longevity." In ADP-Ribosylation: Metabolic Effects and Regulatory Functions, 85–90. Boston, MA: Springer US, 1994. http://dx.doi.org/10.1007/978-1-4615-2614-8_11.

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Zahradka, Peter, and Lorraine Yau. "ADP-ribosylation and gene expression." In ADP-Ribosylation: Metabolic Effects and Regulatory Functions, 91–98. Boston, MA: Springer US, 1994. http://dx.doi.org/10.1007/978-1-4615-2614-8_12.

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Oei, Shiao Li, Herbert Herzog, Monica Hirsch-Kauffmann, Rainer Schneider, Bernhard Auer, and Manfred Schweiger. "Transcriptional regulation and autoregulation of the human gene for ADP-ribosyltransferase." In ADP-Ribosylation: Metabolic Effects and Regulatory Functions, 99–104. Boston, MA: Springer US, 1994. http://dx.doi.org/10.1007/978-1-4615-2614-8_13.

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Conference papers on the topic "Regulatory functions"

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Cooper, Nicholas, Calin Belta, and A. Agung Julius. "Genetic regulatory network identification using multivariate monotone functions." In 2011 50th IEEE Conference on Decision and Control and European Control Conference (CDC-ECC 2011). IEEE, 2011. http://dx.doi.org/10.1109/cdc.2011.6161460.

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Eisenman, Robert. "Abstract IA01: Myc functions within a transcriptional regulatory network." In Abstracts: AACR Special Conference on Myc: From Biology to Therapy; January 7-10, 2015; La Jolla, CA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1557-3125.myc15-ia01.

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Chesi, Graziano. "Genetic networks with SUM regulatory functions: Characterizing the equilibrium points." In 2009 IEEE International Conference on Systems, Man and Cybernetics - SMC. IEEE, 2009. http://dx.doi.org/10.1109/icsmc.2009.5346811.

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Hu, Landian. "Abstract 2122: RNA editing reveals new regulatory functions in tumorigenesis." In Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1538-7445.am2015-2122.

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Campos, Raphael R., Ricardo Ferreira, Julio C. Goldner Vendramini, F´bio Cerqueira, and Marcelo Lobato Martins. "Simulation of Scale Free Gene Regulatory Networks Based on Threshold Functions on GPU." In 2011 Simpasio em Sistemas Computacionais (WSCAD-SSC). IEEE, 2011. http://dx.doi.org/10.1109/wscad-ssc.2011.13.

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Pasquini, Mirko, and David Angeli. "On piecewise quadratic Lyapunov functions for piecewise affine models of gene regulatory networks." In 2018 IEEE Conference on Decision and Control (CDC). IEEE, 2018. http://dx.doi.org/10.1109/cdc.2018.8618671.

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Metzig, Marie Oliver, Simon Mitchell, Brooks Taylor, and Alexander Hoffmann. "Abstract 2326: Time-resolved studies of necroptosis reveal distinct regulatory functions for NFκB." In Proceedings: AACR Annual Meeting 2018; April 14-18, 2018; Chicago, IL. American Association for Cancer Research, 2018. http://dx.doi.org/10.1158/1538-7445.am2018-2326.

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Chang, H., G. Richard, A. A. Julius, C. Belta, and S. Amar. "An application of monotone functions decomposition to the reconstruction of gene regulatory networks." In 2011 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE, 2011. http://dx.doi.org/10.1109/iembs.2011.6090676.

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Pal, Ranadip, Harri Lahdesmaki, Ilya Shmulevich, Olli Yli-Harja, and Edward Dougherty. "On the constraint of gene regulatory networks to canalizing functions and post classes." In 2008 IEEE International Workshop on Genomic Signal Processing and Statistics (GENSIPS). IEEE, 2008. http://dx.doi.org/10.1109/gensips.2008.4555672.

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Nie, Jinsuo R., Jim Xu, and Joseph I. Braverman. "Development of Target Power Spectral Density Functions Compatible With Design Response Spectra." In ASME 2015 Pressure Vessels and Piping Conference. American Society of Mechanical Engineers, 2015. http://dx.doi.org/10.1115/pvp2015-45243.

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For seismic analysis of nuclear structures, synthetic acceleration time histories are often required and are generated to envelop design response spectra following the U.S. Nuclear Regulatory Commission, Standard Review Plan (SRP) Section 3.7.1. It has been recognized that without an additional check of the power spectral density (PSD) functions, spectral matching alone may not ensure that synthetic acceleration time histories have adequate power over the frequency range of interest. The SRP Section 3.7.1 Appendix A provides a target PSD function for the Regulatory Guide 1.60 horizontal spectral shape. For other spectral shapes, additional guidance on developing the target PSD functions compatible with the design spectra is desired. This paper presents a general procedure for the development of target PSD functions for any practical design response spectral shapes, which has been incorporated into the recent SRP 3.7.1, Revision 4.
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Reports on the topic "Regulatory functions"

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Chang, Caren. RTE1, A Novel Regulator of Ethylene Receptor Function. Office of Scientific and Technical Information (OSTI), February 2013. http://dx.doi.org/10.2172/1062076.

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Carpenter, Beth M. Structure Function Analysis of the Ferric Uptake Regulator (Fur) of Helicobacter pylori. Fort Belvoir, VA: Defense Technical Information Center, February 2010. http://dx.doi.org/10.21236/ad1013395.

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Shridhar, Viji. Functional Characterization of a Novel Pro-Apoptotic Transcriptional Regulatory Protein in Ovarian Cancer. Fort Belvoir, VA: Defense Technical Information Center, January 2005. http://dx.doi.org/10.21236/ada434802.

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Shridhar, Viji. Functional Characterization of a Novel Pro-Apoptotic Transcription Regulatory Protein in Ovarian Cancer. Fort Belvoir, VA: Defense Technical Information Center, December 2006. http://dx.doi.org/10.21236/ada470937.

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Zhang, Jisheng. Insight into Skin Tumorigenesis Highlighting the Function of Epigenetic Regulators in SCC Formation. Fort Belvoir, VA: Defense Technical Information Center, October 2013. http://dx.doi.org/10.21236/ada599253.

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Stubbs, L. LDRD Report FY 03: Structure and Function of Regulatory DNA: A Next Major Challenge in Genomics. Office of Scientific and Technical Information (OSTI), February 2003. http://dx.doi.org/10.2172/15003258.

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Cook, Stephen, and Loyd Hook. Developmental Pillars of Increased Autonomy for Aircraft Systems. ASTM International, January 2020. http://dx.doi.org/10.1520/tr2-eb.

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Increased automation for aircraft systems holds the promise to increase safety, precision, and availability for manned and unmanned aircraft. Specifically, established aviation segments, such as general aviation and light sport, could utilize increased automation to make significant progress towards solving safety and piloting difficulties that have plagued them for some time. Further, many emerging market segments, such as urban air mobility and small unmanned (e.g., small parcel delivery with drones) have a strong financial incentive to develop increased automation to relieve the pilot workload, and/or replace in-the-loop pilots for most situations. Before these advances can safely be made, automation technology must be shown to be reliable, available, accurate, and correct within acceptable limits based on the level of risk these functions may create. However since inclusion of these types of systems is largely unprecedented at this level of aviation, what constitutes these required traits (and at what level they must be proven to) requires development as well. Progress in this domain will likely be captured and disseminated in the form of best practices and technical standards created with collaboration from regulatory and industry groups. This work intends to inform those standards producers, along with the system designers, with the goal of facilitating growth in aviation systems toward safe, methodical, and robust inclusion of these new technologies. Produced by members of the manned and unmanned small aircraft community, represented by ASTM task group AC 377, this work strives to suggest and describe certain fundamental principles, or “pillars”, of complex aviation systems development, which are applicable to the design and architectural development of increased automation for aviation systems.
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Francesco, Petruccione,, Gastrow, Michael, Hadzic, Senka, Limpitlaw, Justine, Paul, Babu Sena, Wolhuter, Riaan, and Kies, Carl. Evaluation of Alternative Telecommunication Technologies for the Karoo Central Astronomy Advantage Area. Academy of Science of South Africa (ASSAf), 2021. http://dx.doi.org/10.17159/assaf.2021/0073.

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The National Research Foundation (NRF) requested the Academy of Science of South Africa (ASSAf), on behalf of South African Radio Astronomy Observatory (SARAO) and the Square Kilometre Array (SKA), to undertake an independent and objective evaluation of potential alternative telecommunication technologies for the areas of the Karoo Central Astronomy Advantage Areas (KCAAA). The study encompasses regulatory, public sphere, and technical dimensions to explore options for maintaining the functionality of the telescope while, at the same time, delivering appropriate connectivity solutions for local communities.The objectives of this study are as follows: 1) Assess the technologies currently being, or planning to be, deployed through existing alternative communications programs managed by SARAO, including whether these technologies are comparable with market available technologies that could feasibly be deployed in the KCAAA; and 2) Assessment of current and future telecommunication technologies that may act as suitable replacement and/or improvement (functional and feasible) for existing detrimental technologies, utilised in the KCAAA. This report provides a critical background into the relationship between the SKA and local communities as it relates to ICTs in the area. Based on this understanding, potential technology solutions are proposed to ensure residents of the KCAAA are still afforded valuable access to information and communication technologies (ICTs) within the parameters of affordability, desirability and feasibility.
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Hubbard, Sarah M., and Bryan Hubbard. Investigation of Strategic Deployment Opportunities for Unmanned Aerial Systems (UAS) at INDOT. Purdue University, 2020. http://dx.doi.org/10.5703/1288284317126.

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Unmanned aerial systems (UAS) are increasingly used for a variety of applications related to INDOT’s mission including bridge inspection, traffic management, incident response, construction and roadway mapping. UAS have the potential to reduce costs and increase capabilities. Other state DOTs and transportation agencies have deployed UAS for an increasing number of applications due to technology advances that provide increased capabilities and lower costs, resulting from regulatory changes that simplified operations for small UAS under 55 pounds (aka, sUAS). This document provides an overview of UAS applications that may be appropriate for INDOT, as well as a description of the regulations that affect UAS operation as described in 14 CFR Part 107. The potential applications were prioritized using Quality Function Deployment (QFD), a methodology used in the aerospace industry that clearly communicates qualitative and ambiguous information with a transparent framework for decision making. The factors considered included technical feasibility, ease of adoption and stakeholder acceptance, activities underway at INDOT, and contribution to INDOT mission and goals. Dozens of interviews with INDOT personnel and stakeholders were held to get an accurate and varied perspective of potential for UAVs at INDOT. The initial prioritization was completed in early 2019 and identified three key areas: UAS for bridge inspection safety as a part of regular operations, UAS for construction with deliverables provided via construction contracts, and UAS for emergency management. Descriptions of current practices and opportunities for INDOT are provided for each of these applications. An estimate of the benefits and costs is identified, based on findings from other agencies as well as projections for INDOT. A benefit cost analysis for the application of UAS for bridge inspection safety suggests a benefit cost over one for the analysis period.
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US Nuclear Regulatory Commission functional organization charts. Office of Scientific and Technical Information (OSTI), April 1990. http://dx.doi.org/10.2172/6959035.

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