Relevant bibliographies by topics / Reductase (SDR)

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters
  4. Conference papers
  5. Reports

Academic literature on the topic 'Reductase (SDR)'

Author: Grafiati
Published: 14 March 2023
Last updated: 31 July 2025

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Journal articles on the topic "Reductase (SDR)"

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Gallego, Oriol, Olga V. Belyaeva, Sergio Porté, et al. "Comparative functional analysis of human medium-chain dehydrogenases, short-chain dehydrogenases/reductases and aldo-keto reductases with retinoids." Biochemical Journal 399, no. 1 (2006): 101–9. http://dx.doi.org/10.1042/bj20051988.

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Retinoic acid biosynthesis in vertebrates occurs in two consecutive steps: the oxidation of retinol to retinaldehyde followed by the oxidation of retinaldehyde to retinoic acid. Enzymes of the MDR (medium-chain dehydrogenase/reductase), SDR (short-chain dehydrogenase/reductase) and AKR (aldo-keto reductase) superfamilies have been reported to catalyse the conversion between retinol and retinaldehyde. Estimation of the relative contribution of enzymes of each type was difficult since kinetics were performed with different methodologies, but SDRs would supposedly play a major role because of the
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Gabrielli, Franco, Marco Antinucci, and Sergio Tofanelli. "Gene Structure Evolution of the Short-Chain Dehydrogenase/Reductase (SDR) Family." Genes 14, no. 1 (2022): 110. http://dx.doi.org/10.3390/genes14010110.

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SDR (Short-chain Dehydrogenases/Reductases) are one of the oldest and heterogeneous superfamily of proteins, whose classification is problematic because of the low percent identity, even within families. To get clearer insights into SDR molecular evolution, we explored the splicing site organization of the 75 human SDR genes across their vertebrate and invertebrate orthologs. We found anomalous gene structures in members of the human SDR7C and SDR42E families that provide clues of retrogene properties and independent evolutionary trajectories from a common invertebrate ancestor. The same analy
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Li, Aipeng, Lidan Ye, Xiaohong Yang, Chengcheng Yang, Jiali Gu, and Hongwei Yu. "Structure-guided stereoselectivity inversion of a short-chain dehydrogenase/reductase towards halogenated acetophenones." Chemical Communications 52, no. 37 (2016): 6284–87. http://dx.doi.org/10.1039/c6cc00051g.

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Joles, Jaap, Nel Willekes-Koolschijn, Hein Koomans, et al. "Subcutaneous administration of HMG-CoA reductase inhibitors in hyperlipidaemic and normal rats." Laboratory Animals 26, no. 4 (1992): 269–80. http://dx.doi.org/10.1258/002367792780745689.

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Recent reports demonstrate a hypocholesterolaemic effect of daily subcutaneous injections of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors in different rat models of hyperlipidaemia. However, this effect is not seen after oral administration of HMG-CoA reductase inhibitors in rats. We found that oral administration of the HMG-CoA reductase inhibitor Simvastatin also had no effect on plasma cholesterol in severely hyperlipidaemic Nagase analbuminaemic rats (NAR). Simvastatin (an apolar compound dissolved in propylene glycol) was infused continuously for 28 days into the s
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Davidson, Jaysón, Kyndall Nicholas, Jeremy Young, et al. "Crystal structure of a putative short-chain dehydrogenase/reductase from Paraburkholderia xenovorans." Acta Crystallographica Section F Structural Biology Communications 78, no. 1 (2022): 25–30. http://dx.doi.org/10.1107/s2053230x21012632.

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Paraburkholderia xenovorans degrades organic wastes, including polychlorinated biphenyls. The atomic structure of a putative dehydrogenase/reductase (SDR) from P. xenovorans (PxSDR) was determined in space group P21 at a resolution of 1.45 Å. PxSDR shares less than 37% sequence identity with any known structure and assembles as a prototypical SDR tetramer. As expected, there is some conformational flexibility and difference in the substrate-binding cavity, which explains the substrate specificity. Uniquely, the cofactor-binding cavity of PxSDR is not well conserved and differs from those of ot
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Nguyen, Giang Thu, Shinae Kim, Hyeonseok Jin, et al. "Crystal Structure of NADPH-Dependent Methylglyoxal Reductase Gre2 from Candida Albicans." Crystals 9, no. 9 (2019): 471. http://dx.doi.org/10.3390/cryst9090471.

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Gre2 is a key enzyme in the methylglyoxal detoxification pathway; it uses NADPH or NADH as an electron donor to reduce the cytotoxic methylglyoxal to lactaldehyde. This enzyme is a member of the short-chain dehydrogenase/reductase (SDR) superfamily whose members catalyze this type of reaction with a broad range of substrates. To elucidate the structural features, we determined the crystal structures of the NADPH-dependent methylglyoxal reductase Gre2 from Candida albicans (CaGre2) for both the apo-form and NADPH-complexed form at resolutions of 2.8 and 3.02 Å, respectively. The CaGre2 structur
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Belfon, Kafi K. J., Olive Beyer, Jan Abendroth, et al. "Crystal structure of a short-chain dehydrogenase from Burkholderia cenocepacia J2315 in complex with NADP+ and benzoic acid." Acta Crystallographica Section F Structural Biology Communications 80, no. 12 (2024): 348–55. https://doi.org/10.1107/s2053230x24011282.

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Burkholderia cenocepacia is an opportunistic human pathogen that can cause lethal infections in immunocompromised individuals, particularly those with cystic fibrosis. As such, there is a critical need to identify and characterize the structure and function of enzymes that participate in the metabolic pathways of this bacterium. Here, the high-resolution X-ray crystal structure of a short-chain dehydrogenase reductase (SDR) from B. cenocepacia J2315 (BcSDR) in complex with the coenzyme NADP+ and a benzoic acid ligand is presented. This protein has the conserved Rossmann fold of the SDR superfa
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Sameeullah, Muhammad, Muhammet Yildirim, Noreen Aslam та ін. "Plastidial Expression of 3β-Hydroxysteroid Dehydrogenase and Progesterone 5β-Reductase Genes Confer Enhanced Salt Tolerance in Tobacco". International Journal of Molecular Sciences 22, № 21 (2021): 11736. http://dx.doi.org/10.3390/ijms222111736.

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The short-chain dehydrogenase/reductase (SDR) gene family is widely distributed in all kingdoms of life. The SDR genes, 3β-hydroxysteroid dehydrogenase (3β-HSD) and progesterone 5-β-reductases (P5βR1, P5βR2) play a crucial role in cardenolide biosynthesis pathway in the Digitalis species. However, their role in plant stress, especially in salinity stress management, remains unexplored. In the present study, transplastomic tobacco plants were developed by inserting the 3β-HSD, P5βR1 and P5βR2 genes. The integration of transgenes in plastomes, copy number and transgene expression at transcript a
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Shahri, Mahdi Abedinzadeh, Paniz Shirmast, Seyed Mohammad Ghafoori, and Jade Kenneth Forwood. "Deciphering the structure of a multi-drug resistant Acinetobacter baumannii short-chain dehydrogenase reductase." PLOS ONE 19, no. 2 (2024): e0297751. http://dx.doi.org/10.1371/journal.pone.0297751.

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The rapidly increasing threat of multi-drug-resistant Acinetobacter baumannii infections globally, encompassing a range of clinical manifestations from skin and soft tissue infections to life-threatening conditions like meningitis and pneumonia, underscores an urgent need for novel therapeutic strategies. These infections, prevalent in both hospital and community settings, present a formidable challenge to the healthcare system due to the bacterium’s widespread nature and dwindling effective treatment options. Against this backdrop, the exploration of bacterial short-chain dehydrogenase reduct
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Jacob, Asha I., Sirin A. I. Adham, David S. Capstick, Scott R. D. Clark, Tara Spence, and Trevor C. Charles. "Mutational Analysis of the Sinorhizobium meliloti Short-Chain Dehydrogenase/Reductase Family Reveals Substantial Contribution to Symbiosis and Catabolic Diversity." Molecular Plant-Microbe Interactions® 21, no. 7 (2008): 979–87. http://dx.doi.org/10.1094/mpmi-21-7-0979.

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The short-chain dehydrogenase/reductase (SDR) family is one of the largest and most ubiquitous protein families in bacterial genomes. Despite there being a few well-characterized examples, the substrate specificities or functions of most members of the family are unknown. In this study, we carried out a large-scale mutagenesis of the SDR gene family in the alfalfa root nodule symbiont Sinorhizobium meliloti. Subsequent phenotypic analysis revealed phenotypes for mutants of 21 of the SDR-encoding genes. This brings the total number of S. meliloti SDR-encoding genes with known function or associ
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Dissertations / Theses on the topic "Reductase (SDR)"

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Olandersson, Sandra. "Evaluation of Machine Learning Algorithms for Classification of Short-Chain Dehydrogenase/Reductase Protein Sequences." Thesis, Blekinge Tekniska Högskola, Institutionen för programvaruteknik och datavetenskap, 2003. http://urn.kb.se/resolve?urn=urn:nbn:se:bth-3828.

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The classification of protein sequences is a subfield in the area of Bioinformatics that attracts a substantial interest today. Machine Learning algorithms are here believed to be able to improve the performance of the classification phase. This thesis considers the application of different Machine Learning algorithms to the classification problem of a data set of short-chain dehydrogenases/reductases (SDR) proteins. The classification concerns both the division of the proteins into the two main families, Classic and Extended, and into their different subfamilies. The results of the different
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ROTONDO, ROSSELLA. "New enzymatic pathway(s) in 4-hydroxynonenal metabolism." Doctoral thesis, Università di Siena, 2017. http://hdl.handle.net/11365/1007903.

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The main effect of lipid peroxidation, which often occurs in response to oxidative stress, is the production of different toxic aldehydes. In particular, over the years, the lipid peroxidation-derived aldehyde 4-hydroxy-trans-2-nonenal (HNE) has received much attention for its dual role in the pathogenesis of several diseases and as signaling molecule. HNE metabolism is reported to mainly occur through its conjugation with glutathione (GSH) and the subsequent formation of 3-glutathionyl-4-hydroxynonanal (GSHNE) [1, 2]. This molecule is susceptible to both oxidative and reductive transformation
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Heyno, Eiri. "Enzymes impliqués dans la production des formes réactives de l'oxygène dans les membranes plasmiques, les mitochrondries et les chloroplastes." Phd thesis, Université Paris Sud - Paris XI, 2009. http://tel.archives-ouvertes.fr/tel-00447102.

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Les formes réactives de l'oxygène (FRO) ont été analysées dans différents compartiments cellulaires en utilisant des méthodes spectroscopiques (UV/VIS, fluorescence, infrarouge, résonance paramagnétique électronique). L'identité et les mécanismes catalytiques des enzymes qui produisent les FRO dans les membranes plasmiques (MP) et les mitochondries ont été étudiés, ainsi que le rôle protectif de l'oxydase terminale plastidiale (PTOX) des chloroplastes. Cd2+ s'est révélé être un inhibiteur de la NADPH oxydase des MP. In vivo Cd2+ inhibait la production extracellulaire de O2•- mais stimulait l'a
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lson, Timothy Simbarashe Wilson Timothy. "HC-SCR of NOˣ emissions over Ag-Al₂O₃ catalysts using diesel fuel as a reductant". Thesis, University of Birmingham, 2011. http://etheses.bham.ac.uk//id/eprint/1338/.

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Hydrocarbon selective catalytic reduction (HC-SCR) of nitrogen oxides (NOˣ) over silver-alumina (Ag-Al₂O₃) catalysts, in diesel exhaust gas, has been investigated and presented in this research thesis. The work involved the use of H₂ to activate diesel-type HC reductants. Numerous HC-SCR studies have been conducted (to date) by various authors and research groups in an effort to improve the low temperature (< 350 °C) NOˣ reduction activity of the catalyst, but mainly at laboratory scale, using simulated diesel exhaust gases and the pelletized form of the catalyst. Conversely, the work presente
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Gaziola, Salete Aparecida. "Isolamento, purificação, caracterização e estudo dos mecanismos de regulação das enzimas lisina oxoglutarato reductase (LOR) e sacaropina desidrogenase (SDH) em arroz (Oriza sativa L.)." [s.n.], 1999. http://repositorio.unicamp.br/jspui/handle/REPOSIP/317253.

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Orientador: Ricardo Antunes Azevedo<br>Tese (doutorado) - Universidade Estadual de Campinas, Instituto de Biologia<br>Made available in DSpace on 2018-07-28T15:50:03Z (GMT). No. of bitstreams: 1 Gaziola_SaleteAparecida_D.pdf: 4051671 bytes, checksum: 69f5c5ae7cb94c0486211b621052970f (MD5) Previous issue date: 1999<br>Doutorado<br>Genetica Vegetal e Melhoramento<br>Doutor em Genetica e Biologia Molecular
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Gong, Wenjie [Verfasser]. "Characterization of the LysR-type Transcriptional Regulator HsdR Gene and Its Adjacent Short-chain Dehydrogenase, Reductase SDRx Gene in Comamonas testosteroni ATCC 11996 / Wenjie Gong." Kiel : Universitätsbibliothek Kiel, 2011. http://d-nb.info/1020244666/34.

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Ayella, Allan K. "Wheat lignans and cancer prevention." Diss., Manhattan, Kan. : Kansas State University, 2007. http://hdl.handle.net/2097/335.

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Rosa, Joana Alexandra Teixeira. "Identification of novel molecular determinants of tissue mineralization in fish." Doctoral thesis, 2015. http://hdl.handle.net/10400.1/8756.

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Tese de doutoramento, Ciências Biomédicas, Departamento de Ciências Biomédicas e Medicina, Universidade do Algarve, 2015<br>The identification of genes involved in signaling and regulatory pathways, and matrix formation is paramount to the better understanding of the complex mechanisms of bone formation and mineralization, and critical to the successful development of therapies for human skeletal disorders. To achieve this objective, in vitro cell systems derived from skeletal tissues and able to mineralize their extracellular matrix have been used to identify genes differentially expressed du
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Jacob, Asha Ivy. "STUDY OF SHORT CHAIN DEHYDROGENASE / REDUCTASES (SDRs) IN SINORHIZOBIUM MELILOTI." Thesis, 2007. http://hdl.handle.net/10012/3346.

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Sinorhizobium meliloti maintains a complex lifestyle, including saprotrophy, rhizophere colonization and root hair infection leading to the formation of root nodules in which the plant provides sustenance in return for nitrogen fixation. S. meliloti cells use a variety of carbon substrates for growth; this omnivory probably contributes to competitive ability in the soil. Several candidates for contribution to the catabolic capacity are found within the family of short chain dehydrogenases /reductases (SDR), which catalyze NAD(P)(H) dependent oxidation / reduction reactions. The 6.7 Mb genome
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陳定威. "Synthesis of vitamin K 2,3-epoxide reductase inhibitors and SAR studies." Thesis, 2003. http://ndltd.ncl.edu.tw/handle/49974423267304640953.

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Book chapters on the topic "Reductase (SDR)"

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Furnham, Nicholas, Gemma L. Holliday, and Janet M. Thornton. "The NAD Binding Domain and the Short-Chain Dehydrogenase/Reductase (SDR) Superfamily." In Protein Families. John Wiley & Sons, Inc., 2013. http://dx.doi.org/10.1002/9781118743089.ch8.

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"Carboxylic Acid Reductase." In Biocatalysis in Organic Synthesis, edited by Faber, Fessner, and Turner. Georg Thieme Verlag, 2015. http://dx.doi.org/10.1055/sos-sd-215-00257.

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"Imine Reductases." In Biocatalysis in Organic Synthesis, edited by Faber, Fessner, and Turner. Georg Thieme Verlag, 2015. http://dx.doi.org/10.1055/sos-sd-215-00205.

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Nubbemeyer, U. "Reductive Defluorination." In X-Ene-X (X=F, Cl, Br, I, O, S, Se, Te, N, P), Ene-Hal, and Ene-O Compounds. Georg Thieme Verlag KG, 2008. http://dx.doi.org/10.1055/sos-sd-032-00081.

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Nubbemeyer, U. "Reductive Dechlorination." In X-Ene-X (X=F, Cl, Br, I, O, S, Se, Te, N, P), Ene-Hal, and Ene-O Compounds. Georg Thieme Verlag KG, 2008. http://dx.doi.org/10.1055/sos-sd-032-00082.

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Nubbemeyer, U. "Reductive Coupling." In X-Ene-X (X=F, Cl, Br, I, O, S, Se, Te, N, P), Ene-Hal, and Ene-O Compounds. Georg Thieme Verlag KG, 2008. http://dx.doi.org/10.1055/sos-sd-032-00084.

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Nubbemeyer, U. "Reductive Alkylation." In X-Ene-X (X=F, Cl, Br, I, O, S, Se, Te, N, P), Ene-Hal, and Ene-O Compounds. Georg Thieme Verlag KG, 2008. http://dx.doi.org/10.1055/sos-sd-032-00184.

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Toyota, S., and T. Iwanaga. "Reductive Cyclization." In Monocyclic Arenes, Quasiarenes, and Annulenes. Georg Thieme Verlag KG, 2010. http://dx.doi.org/10.1055/sos-sd-045-00722.

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Donohoe, T. J. "Reductive Cyclization." In Fused Five-Membered Hetarenes with One Heteroatom. Georg Thieme Verlag KG, 2001. http://dx.doi.org/10.1055/sos-sd-010-00817.

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Aitken, R. A. "Reductive Elimination." In Fused Five-Membered Hetarenes with One Heteroatom. Georg Thieme Verlag KG, 2001. http://dx.doi.org/10.1055/sos-sd-010-01138.

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Conference papers on the topic "Reductase (SDR)"

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M, Jayashree, Sabareeswaran K, and Ananth Kumar YS. "On- Board Diagnosis of Improper Reductant Detection in BS6 SCR System Using Virtual Sensor Modelling." In Symposium on International Automotive Technology. SAE International, 2024. http://dx.doi.org/10.4271/2024-26-0256.

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&lt;div class="section abstract"&gt;&lt;div class="htmlview paragraph"&gt;Selective Catalytic Reduction (SCR) is an optimized technology developed to encounter current BS6 Emission Regulations. AdBlue is the reductant used in the SCR Dosing system to eliminate NOx in the Exhaust gas. In order to ensure engine emissions compliance, insufficient or improper reductant in tank required to be detected. The right AdBlue concentration of 32.5% is highly necessary to attain the higher NOX conversion efficiency. Low concentration of the reductant will drastically reduce the NOx conversion in the system
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Newburry, Don, Pat Runnels, and Mike Owings. "Selective Catalytic Reduction (SCR) System Installation and Commissioning at the Chow II Power Plant in Chowchilla, California." In ASME 2003 Internal Combustion Engine Division Spring Technical Conference. ASMEDC, 2003. http://dx.doi.org/10.1115/ices2003-0594.

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Lean burn, natural gas, reciprocating engines are becoming widely utilized for stationary industrial applications due to their high efficiency and low emissions. However, despite the low engine emissions, some locations still require exhaust after-treatment to meet the local emissions requirements. Due to the high oxygen content (greater than 4%) in the exhaust of lean burn engines, 3-Way (non-selective) catalysts are not suitable to reduce NOx. Selective catalytic reduction (SCR), which utilizes a consumable reductant to reduce NOx over a catalyst, is very effective at reducing NOx and is bec
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Shuai, Shijin, Jianxin Wang, Rulong Li, et al. "Performance Evaluation and Application of Diesel NOx-SCR Catalyst by Ethanol Reductant." In SAE 2005 World Congress & Exhibition. SAE International, 2005. http://dx.doi.org/10.4271/2005-01-1089.

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van Vuuren, Nic. "Initial Evaluations of Injector Compatibility with an Alternative SCR Reductant Carrier - Guanidinium Formate." In SAE 2014 World Congress & Exhibition. SAE International, 2014. http://dx.doi.org/10.4271/2014-01-1532.

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Li, Jie, and Jian Li. "A New Proposal on Reductant Utilization in Flue Gas SCR De-NOx Process." In 2nd International Conference on Material Science, Energy and Environmental Engineering (MSEEE 2018). Atlantis Press, 2018. http://dx.doi.org/10.2991/mseee-18.2018.42.

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Chuang Wang, Xinmei Yuan, and Jian Zhang. "On-board detection of SCR system insufficient and improper reductant by magnetically coupled resonators." In 2015 IEEE International Wireless Symposium (IWS). IEEE, 2015. http://dx.doi.org/10.1109/ieee-iws.2015.7164546.

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Lacin, Figen, Adam Kotrba, Granville Hayworth, et al. "SOLID SCR®: Demonstrating an Improved Approach to NOx Reduction via a Solid Reductant." In Commercial Vehicle Engineering Congress. SAE International, 2011. http://dx.doi.org/10.4271/2011-01-2207.

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Ambalakatte, Ajith, Sikai Geng, Reese Murugan, et al. "A Comparison of Stoichiometric and Lean Burn Ammonia-Hydrogen Co-Fuelling in a Modern Spark Ignition Engine." In WCX SAE World Congress Experience. SAE International, 2025. https://doi.org/10.4271/2025-01-8432.

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&lt;div class="section abstract"&gt;&lt;div class="htmlview paragraph"&gt;Ammonia (NH&lt;sub&gt;3&lt;/sub&gt;) is emerging as a promising fuel for longer range decarbonised heavy transport, predominantly due to relative favourable characteristics as an effective hydrogen carrier. This is despite generally unfavourable combustion and toxicity attributes, restricting ammonia’s end use to applications where robust health and safety protocols can always be assured. In the currently reported work, a spark ignited thermodynamic single cylinder research engine was equipped with separate gaseous ammon
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Liu, Yue, Zaixia Teng, Yafeng Yin, and Guo-Zheng Li. "Using Rough Reducts Based SVM Ensemble for SAR of the Ethofenprox Analogous of Pesticide." In 2008 International Multi-symposiums on Computer and Computational Sciences (IMSCCS). IEEE, 2008. http://dx.doi.org/10.1109/imsccs.2008.34.

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Srisailam, Shravan Kumar, Joe Patchett, Ralph Wu, Lu Wang, Sandip Shah, and Weiyong Tang. "Exhaust after Treatment Solution for H <sub>2</sub> -ICE for Selective NO <sub>x</sub> Removal in the Presence of High Amount of Water Content." In Symposium on International Automotive Technology. SAE International, 2024. http://dx.doi.org/10.4271/2024-26-0146.

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&lt;div class="section abstract"&gt;&lt;div class="htmlview paragraph"&gt;North America and Europe are implementing alternate fuels meet the goals of reducing carbon dioxide emissions and creating a sustainable environment. India too has promised to cut down emissions and become CO2 net neutral by 2070. One alternate fuel which has gained importance recently is hydrogen. With the announcement of National Hydrogen Mission by the Government of India in 2023, there has been an increased attention on the hydrogen fuel-based mobility. Technologies like H&lt;sub&gt;2&lt;/sub&gt;-Fuel cell and a hydr
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Reports on the topic "Reductase (SDR)"

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Or, Etti, David Galbraith, and Anne Fennell. Exploring mechanisms involved in grape bud dormancy: Large-scale analysis of expression reprogramming following controlled dormancy induction and dormancy release. United States Department of Agriculture, 2002. http://dx.doi.org/10.32747/2002.7587232.bard.

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The timing of dormancy induction and release is very important to the economic production of table grape. Advances in manipulation of dormancy induction and dormancy release are dependent on the establishment of a comprehensive understanding of biological mechanisms involved in bud dormancy. To gain insight into these mechanisms we initiated the research that had two main objectives: A. Analyzing the expression profiles of large subsets of genes, following controlled dormancy induction and dormancy release, and assessing the role of known metabolic pathways, known regulatory genes and novel se
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