Relevant bibliographies by topics / Recombination

Academic literature on the topic 'Recombination'

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Published: 4 June 2021
Last updated: 8 June 2024

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Journal articles on the topic "Recombination"

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Persiani, D. M., J. Durdik, and E. Selsing. "Active lambda and kappa antibody gene rearrangement in Abelson murine leukemia virus-transformed pre-B cell lines." Journal of Experimental Medicine 165, no. 6 (June 1, 1987): 1655–74. http://dx.doi.org/10.1084/jem.165.6.1655.

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The two Abelson murine leukemia virus (A-MuLV)-transformed cell lines, BM18-4 and ABC-1, undergo immunoglobulin L-chain gene recombination during passage in tissue culture. BM18-4 cells are capable of kappa gene recombination, whereas ABC-1 cells are capable of both kappa and lambda gene recombination. The expression of H chains is apparently not necessary for continuing L chain gene recombination in either of these cells, although H-chain expression may have been involved in the initiation of L-chain gene recombination. All ABC-1 cells that have lambda gene rearrangements also display recombined kappa alleles, supporting the hypothesis that kappa and lambda gene recombination are initiated in an ordered, developmentally regulated manner in maturing B cells. However, analyses of the ABC-1 line indicate that pre-B cells that have initiated lambda gene recombination do not terminate kappa gene rearrangement. The lambda gene recombinations that occur in the ABC-1 cell line indicate that the germline order of lambda gene segments is: 5' ... V lambda 2 ... J lambda 2C lambda 2-J lambda 4C lambda 4 ... V lambda 1 ... J lambda 3C lambda 3-J lambda 1C lambda 1 ... 3'. In addition, the frequencies of lambda 1, lambda 2, and lambda 3 gene recombinations among ABC-1 cells are quite different than the frequencies of B cells producing lambda 1, lambda 2, and lambda 3 L-chains in the mouse. RS DNA recombinations also occur in the BM18-4 and ABC-1 cell lines, supporting the notion that Ig gene recombinases are involved in RS rearrangement. Recombined RS segments are infrequent among BM 18-4 cells but common among ABC-1 cells, suggesting that RS recombinational events often occur in maturing pre-B cells just before initiation of lambda gene rearrangements. This developmental timing is consistent with the hypothesis that RS recombination may be involved in the initiation of lambda gene assembly.
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STAUFFER, D., and S. CEBRAT. "EXTINCTION IN GENETIC BIT-STRING MODEL WITH SEXUAL RECOMBINATION." Advances in Complex Systems 09, no. 01n02 (March 2006): 147–56. http://dx.doi.org/10.1142/s0219525906000653.

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We have analyzed the relations between the mutational pressure, recombination and selection pressure in the bit-string model with sexual reproduction. For specific sets of these parameters, we have found three phase transitions with one phase where populations can survive. In this phase, recombination enhances the survival probability. Even if recombination is associated, to some extent, with additional mutations it could be advantageous to reproduction, indicating that the frequencies of recombinations and recombination-associated mutations can self-organize in Nature. Partitioning the diploid genome into pairs of chromosomes independently assorted during gamete production enables recombinations between groups of genes without the risk of mutations and is also advantageous for the strategy of sexual reproduction.
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Nebrin, Olof. "Case A or Case B? The Effective Recombination Coefficient in Gas Clouds of Arbitrary Optical Thickness." Research Notes of the AAS 7, no. 5 (May 10, 2023): 90. http://dx.doi.org/10.3847/2515-5172/acd37a.

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Abstract In calculations of the ionization state, one is often forced to choose between the Case A recombination coefficient α A (sum over recombinations to all hydrogen states) or the Case B recombination coefficient α B (sum over all hydrogen states except the ground state). If the cloud is optically thick to ionizing photons, α B is usually adopted on the basis of the “on-the-spot” approximation, wherein recombinations to the ground state are ignored because they produce ionizing photons absorbed nearby. In the opposite case of an optically thin cloud, one would expect the Case A recombination coefficient to better describe the effective recombination rate in the cloud. In this paper, I derive an analytical expression for the effective recombination coefficient in a gas cloud of arbitrary optical thickness which transitions from α A to α B as the optical thickness increases. The results can be readily implemented in numerical simulations and semi-analytical calculations.
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Kuzminov, Andrei. "Recombinational Repair of DNA Damage inEscherichia coli and Bacteriophage λ." Microbiology and Molecular Biology Reviews 63, no. 4 (December 1, 1999): 751–813. http://dx.doi.org/10.1128/mmbr.63.4.751-813.1999.

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SUMMARY Although homologous recombination and DNA repair phenomena in bacteria were initially extensively studied without regard to any relationship between the two, it is now appreciated that DNA repair and homologous recombination are related through DNA replication. In Escherichia coli, two-strand DNA damage, generated mostly during replication on a template DNA containing one-strand damage, is repaired by recombination with a homologous intact duplex, usually the sister chromosome. The two major types of two-strand DNA lesions are channeled into two distinct pathways of recombinational repair: daughter-strand gaps are closed by the RecF pathway, while disintegrated replication forks are reestablished by the RecBCD pathway. The phage λ recombination system is simpler in that its major reaction is to link two double-stranded DNA ends by using overlapping homologous sequences. The remarkable progress in understanding the mechanisms of recombinational repair in E. coli over the last decade is due to the in vitro characterization of the activities of individual recombination proteins. Putting our knowledge about recombinational repair in the broader context of DNA replication will guide future experimentation.
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Myers, Simon R., and Robert C. Griffiths. "Bounds on the Minimum Number of Recombination Events in a Sample History." Genetics 163, no. 1 (January 1, 2003): 375–94. http://dx.doi.org/10.1093/genetics/163.1.375.

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Abstract Recombination is an important evolutionary factor in many organisms, including humans, and understanding its effects is an important task facing geneticists. Detecting past recombination events is thus important; this article introduces statistics that give a lower bound on the number of recombination events in the history of a sample, on the basis of the patterns of variation in the sample DNA. Such lower bounds are appropriate, since many recombination events in the history are typically undetectable, so the true number of historical recombinations is unobtainable. The statistics can be calculated quickly by computer and improve upon the earlier bound of Hudson and Kaplan (1985). A method is developed to combine bounds on local regions in the data to produce more powerful improved bounds. The method is flexible to different models of recombination occurrence. The approach gives recombination event bounds between all pairs of sites, to help identify regions with more detectable recombinations, and these bounds can be viewed graphically. Under coalescent simulations, there is a substantial improvement over the earlier method (of up to a factor of 2) in the expected number of recombination events detected by one of the new minima, across a wide range of parameter values. The method is applied to data from a region within the lipoprotein lipase gene and the amount of detected recombination is substantially increased. Further, there is strong clustering of detected recombination events in an area near the center of the region. A program implementing these statistics, which was used for this article, is available from http://www.stats.ox.ac.uk/mathgen/programs.html.
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Kleinfield, R. W., and M. G. Weigert. "Analysis of VH gene replacement events in a B cell lymphoma." Journal of Immunology 142, no. 12 (June 15, 1989): 4475–82. http://dx.doi.org/10.4049/jimmunol.142.12.4475.

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Abstract We have analyzed a series of recombinational events at the IgH chain locus of the B cell lymphoma, NFS-5. Each of these recombinational events results in the replacement of the VH gene segment of the rearranged H chain gene (VhDJh) with that of an upstream germline gene segment. Replacements on the productive and nonproductive alleles have been observed. In each case, the recombination occurs in close proximity to a highly conserved heptameric sequence (5'TACTGTG3') which is located at the 3' end of the VH coding region. In the two examples of recombination on the productive allele that have been analyzed, the initial VHQ52 gene is replaced by different VH7183 genes. On the non-productive allele, sequential replacement events have been analyzed: the initial VHQ52 rearrangement is first replaced by a closely related VHQ52 gene, followed by a second replacement using a VHQ52 pseudogene. Southern blot analysis using VH probes indicates that these recombinations may be accompanied by the deletion of germline VH genes belonging to both the VHQ52 and VH7183 families, suggesting that these gene families are interspersed in the NFS/N mouse.
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CERBANIC, GEORGETA, IOAN BURDA, and SIMION SIMON. "RECOMBINATION PARAMETERS OF CdxI1-xSe EPITAXIAL LAYERS FROM THE PHOTOCONDUCTIVE EFFECT." Modern Physics Letters B 15, no. 27 (November 20, 2001): 1225–30. http://dx.doi.org/10.1142/s0217984901003135.

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The study of lifetimes regarding the recombination of non-equilibrium carriers and their kinetics is essential in order to explain the recombination mechanisms in semiconductors. The study of recombination kinetics and lifetime values in CdSe epitaxial layers is the target of this paper. CdSe layers have been deposited on (0001) mica substrates by vapor epitaxial method. The epitaxial layers contain defects that induce gap states and specific recombination kinetics. The lifetimes were determined by photoconductive frequency-resolved spectroscopy (PCFRS), a usual method for such measurements. The lifetime spectra obtained show in all studied samples the presence of three types of recombinations: τ1 is due to band-to-band recombination, τ2 to surface recombination associated with chemical impurities and τ3 to surface recombination associated with structural defects. The lifetime measured as a function of the substrate temperature denotes a complex correlation between the crystal perfection and the growth temperature.
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Petrini, J., and W. A. Dunnick. "Products and implied mechanism of H chain switch recombination." Journal of Immunology 142, no. 8 (April 15, 1989): 2932–35. http://dx.doi.org/10.4049/jimmunol.142.8.2932.

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Abstract The Ig H chain switch is a DNA recombination event. The recombination occurs between two or more switch regions, areas of tandem sequence duplication that lie upstream of the corresponding H chain C region genes. We have determined the DNA sequence at four recombination sites in three molecularly cloned, rearranged switch regions. All eight donor and recipient recombination sites are at the common pentamers GGGGT, GAGCT, and GGTGG. One of the switch recombination events is an inversion of S gamma 3 sequences. Another of the recombinational events is an internal S gamma 1 deletion, which may be switch enzyme mediated. These results, together with other switch recombination site sequences, suggest that switch recombination is mediated by cutting enzymes with modest specificity and religation enzymes with no specificity.
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Li, Ting, and Jiayou Zhang. "Intramolecular Recombinations of Moloney Murine Leukemia Virus Occur during Minus-Strand DNA Synthesis." Journal of Virology 76, no. 19 (October 1, 2002): 9614–23. http://dx.doi.org/10.1128/jvi.76.19.9614-9623.2002.

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ABSTRACT Retroviral recombination can occur between two viral RNA molecules (intermolecular) or between two sequences within the same RNA molecule (intramolecular). The rate of retroviral intramolecular recombination is high. Previous studies showed that, after a single round of replication, 50 to 60% of retroviral recombinations occur between two identical sequences within a Moloney murine leukemia virus-based vector. Recombination can occur at any polymerization step within the retroviral replication cycle. Although reverse transcriptase is assumed to contribute to the template switches, previous studies could not distinguish between changes introduced by host RNA polymerase II (Pol II) or by reverse transcriptase. A cell culture system has been established to detect the individual contribution of host RNA Pol II, host DNA polymerase or viral reverse transcriptase, as well as the recombination events taking place during minus-strand DNA synthesis and plus-strand DNA synthesis in a single round of viral intramolecular replication. Studies in this report demonstrate that intramolecular recombination between two identical sequences during transcription by host RNA Pol II is minimal and that most recombinations occur during minus-strand DNA synthesis catalyzed by viral reverse transcriptase.
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Coutinho, Thamara Carvalho, Telles Timóteo Da Silva, and Gustavo Leal Toledo. "Recombination and Genetic Diversity." TEMA (São Carlos) 13, no. 3 (December 22, 2012): 265–75. http://dx.doi.org/10.5540/tema.2013.013.03.0265.

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In this paper we present a spatial stochastic model for genetic recombination, that answers if diversity is preserved in an infinite population of recombinating individuals distributed spatially. We show that, for finite times, recombination may maintain all the various potential different types, but when time grows infinitely, the diversity of individuals extinguishes off. So under the model premisses, recombination and spatial localization alone are not enough to explain diversity in a population. Further we discuss an application of the model to a controversy regarding the diversity of "Major Histocompatibility Complex" (MHC).
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Dissertations / Theses on the topic "Recombination"

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Wong, Wan Yan. "Cosmological recombination." Thesis, University of British Columbia, 2008. http://hdl.handle.net/2429/5348.

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In this thesis we focus on studying the physics of cosmological recombination and how the details of recombination affect the Cosmic Microwave Back ground (CMB) anisotropies. We present a detailed calculation of the spectral line distortions on the CMB spectrum arising from the Ly α and two-photon transitions in the recombination of hydrogen (H), as well as the corresponding lines from helium (He). The peak of these distortions mainly comes from the Ly α transition and occurs at about 170 μm, which is the Wien part of the CMB. The detection of this distortion would provide the most direct supporting evidence that the Universe was indeed once a plasma. The major theoretical limitation for extracting cosmological parameters from the CMB sky lies in the precision with which we can calculate the cosmologi cal recombination process. Uncertainty in the details of hydrogen and helium recombination could effectively increase the errors or bias the values of the cos mological parameters derived from microwave anisotropy experiments. With this motivation, we perform a multi-level calculation of the recombination of H and He with the addition of the spin-forbidden transition for neutral helium (He I), plus the higher order two-photon transitions for H and among singlet states of He I. Here, we relax the thermal equilibrium assumption among the higher excited states to investigate the effect of these extra forbidden transitions on the ionization fraction Xe and the CMB angular power spectrum C. We find that the inclusion of the spin-forbidden transition results in more than a percent change in Xe, while the higher order non-resonance two-photon transitions give much smaller effects compared with previous studies. Lastly we modify the cosmological recombination code RECFAST by introduc ing one more parameter to reproduce recent numerical results for the speed-up of helium recombination. Together with the existing hydrogen ‘fudge factor’, we vary these two parameters to account for the remaining dominant uncertainties in cosmological recombination. By using a Markov Chain Monte Carlo method with Planck forecast data, we find that we need to determine the parameters to better than 10% for HeT and 1% for H, in order to obtain negligible effects on the cosmological parameters.
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Naylor, G. A. "Recombination lasers." Thesis, University of Oxford, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.355788.

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Loveland, Damien Gerard. "Collisional recombination lasers." Thesis, University of Oxford, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.305502.

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Walters, K. "Genetic recombination processes." Thesis, University of Sheffield, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.269336.

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Torres, J. T. "homologous genetic recombination." Thesis, London School of Hygiene and Tropical Medicine (University of London), 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.431205.

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Griffin, Craig David. "Genome recombination studies." Thesis, University of Leicester, 2004. http://hdl.handle.net/2381/30354.

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In the Saccharomyces cerevisiae genome the regions adjacent to the 32 chromosome ends, the subtelomeres, are tethered at the nuclear periphery during vegetative / somatic growth and during sporulation / gametogenesis. This is in contrast to the rest of the genome, the interstitial regions, which are located throughout the nucleus. There is evidence that recombination between different subtelomeres is the exceptionally frequent, but that subtelomeres and interstitial regions do not recombine. These features of recombination involving subtelomeres may result from a structure that interacts with the subtelomeres, partitioning them from interstitial regions. Our aim was to characterise which part of the subtelomeres this recombination barrier interacts with. As a tool for estimating the rate and efficiency of recombination between different regions, a set of insertions into the S. cerevisiae genome was engineered. This set included 11 insertions at regular intervals along the terminal 10% of one chromosome arm, marking an interstitial region and the subtelomere. In addition, insertions were also made into a sample of other subtelomeres and interstitial regions. Both recombination during vegetative growth (mitotic recombination) and during sporulation (meiotic recombination) were assayed, between numerous combinations of these insertions. In agreement with previous studies, our results indicate that recombination between interstitial regions and subtelomeres is less efficient than recombination between different interstitial regions. Moreover, this is true of both mitotic and meiotic recombination. However, our efficiency data indicate this may result from tethering of subtelomeres at the nuclear periphery, rather than a partition in the nucleus. Tethering may suppress recombination between subtelomeres and most interstitial regions, simply by maintaining a large relative distance between these two regions. In contrast, the efficiency of mitotic and meiotic recombination between subtelomeres appear to be very different. Mitotic recombination between different subtelomeres appears to be exceptionally efficient, while meiotic recombination between different subtelomeres appears to be inefficient.
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Larson, Åsa. "Dynamics in dissociative recombination." Doctoral thesis, KTH, Physics, 2001. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-3107.

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Larson, Åsa. "Dynamics in dissociative recombination /." Stockholm, 2001. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-3107.

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Mirza, Memona. "Genetic recombination in yeast." Thesis, University of Oxford, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.357567.

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Robertson, David L. "Recombination in primate lentiviruses." Thesis, University of Nottingham, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.336866.

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Books on the topic "Recombination"

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Waldman, Alan S. Genetic Recombination. New Jersey: Humana Press, 2004. http://dx.doi.org/10.1385/1592597610.

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Aguilera, Andrés, and Aura Carreira, eds. Homologous Recombination. New York, NY: Springer US, 2021. http://dx.doi.org/10.1007/978-1-0716-0644-5.

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Rowe, Bertrand R., J. Brian A. Mitchell, and André Canosa, eds. Dissociative Recombination. Boston, MA: Springer US, 1993. http://dx.doi.org/10.1007/978-1-4615-2976-7.

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Tsubouchi, Hideo, ed. DNA Recombination. Totowa, NJ: Humana Press, 2011. http://dx.doi.org/10.1007/978-1-61779-129-1.

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Leach, David. Genetic recombination. Oxford [England]: Blackwell Science, 1996.

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1944-, Wilson John H., ed. Genetic recombination. Menlo Park, Calif: Benjamin/Cummings Pub. Co., 1985.

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Egel, Richard, and Dirk-Henner Lankenau, eds. Recombination and Meiosis. Berlin, Heidelberg: Springer Berlin Heidelberg, 2008. http://dx.doi.org/10.1007/978-3-540-68984-3.

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Gordon, M. A., and R. L. Sorochenko. Radio Recombination Lines. New York, NY: Springer New York, 2009. http://dx.doi.org/10.1007/978-0-387-09691-9.

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Gordon, M. A., and R. L. Sorochenko. Radio Recombination Lines. Dordrecht: Springer Netherlands, 2002. http://dx.doi.org/10.1007/978-94-010-0261-5.

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Egel, Richard, and Dirk-Henner Lankenau, eds. Recombination and Meiosis. Berlin, Heidelberg: Springer Berlin Heidelberg, 2008. http://dx.doi.org/10.1007/978-3-540-75373-5.

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Book chapters on the topic "Recombination"

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Viguera, Enrique. "Recombination." In Encyclopedia of Astrobiology, 1438–39. Berlin, Heidelberg: Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-11274-4_1351.

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Chu, Junhao, and Arden Sher. "Recombination." In Device Physics of Narrow Gap Semiconductors, 125–201. New York, NY: Springer New York, 2009. http://dx.doi.org/10.1007/978-1-4419-1040-0_3.

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Zhou, Zhi-Hua, Yang Yu, and Chao Qian. "Recombination." In Evolutionary Learning: Advances in Theories and Algorithms, 93–108. Singapore: Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-5956-9_8.

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Grundmann, Marius. "Recombination." In Graduate Texts in Physics, 309–44. Berlin, Heidelberg: Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-642-13884-3_10.

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Viguera, Enrique. "Recombination." In Encyclopedia of Astrobiology, 2156–57. Berlin, Heidelberg: Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-662-44185-5_1351.

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Durrett, Richard. "Recombination." In Probability and its Applications, 83–124. New York, NY: Springer New York, 2008. http://dx.doi.org/10.1007/978-0-387-78168-6_3.

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Hofrichter, Julian, Jürgen Jost, and Tat Dat Tran. "Recombination." In Understanding Complex Systems, 103–22. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-52045-2_5.

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Leppla, Norman C., Bastiaan M. Drees, Allan T. Showler, John L. Capinera, Jorge E. Peña, Catharine M. Mannion, F. William Howard, et al. "Recombination." In Encyclopedia of Entomology, 3109. Dordrecht: Springer Netherlands, 2008. http://dx.doi.org/10.1007/978-1-4020-6359-6_3310.

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Montanucci, Ludovica, and Jaume Bertranpetit. "Recombination." In Evolution of the Human Genome I, 131–42. Tokyo: Springer Japan, 2017. http://dx.doi.org/10.1007/978-4-431-56603-8_6.

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Datta, Surja, Sandeep Roy, and Tobias Kutzewski. "Recombination." In Unlocking Strategic Innovation, 46–72. New York: Routledge, 2021.: Routledge, 2021. http://dx.doi.org/10.4324/9780429317514-4.

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Conference papers on the topic "Recombination"

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Phuong Thao, Nguyen Thi, and Le Sy Vinh. "Building minimum recombination ancestral recombination graphs for whole genomes." In 2017 4th NAFOSTED Conference on Information and Computer Science. IEEE, 2017. http://dx.doi.org/10.1109/nafosted.2017.8108072.

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Friedrich, Tobias, Timo Kötzing, Francesco Quinzan, and Andrew M. Sutton. "Resampling vs Recombination." In the 14th ACM/SIGEVO Conference. New York, New York, USA: ACM Press, 2017. http://dx.doi.org/10.1145/3040718.3040723.

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Halma, Arvid, and Remi Turk. "Adaptive markov recombination." In the 9th annual conference. New York, New York, USA: ACM Press, 2007. http://dx.doi.org/10.1145/1276958.1277245.

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Kanade, Varun. "Evolution with Recombination." In 2011 IEEE 52nd Annual Symposium on Foundations of Computer Science (FOCS). IEEE, 2011. http://dx.doi.org/10.1109/focs.2011.24.

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Vuchkov, N. K., and D. N. Astadjov. "Strontium recombination laser." In The European Conference on Lasers and Electro-Optics. Washington, D.C.: Optica Publishing Group, 1994. http://dx.doi.org/10.1364/cleo_europe.1994.cthq4.

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The IC-excitation that had been developed in our lab has been applied very successfully in the excitation of CuBr vapor laser.1 The power and efficiency of CuBr vapor lasers have been increased by a factor of 1.5-1.7. In the present work we present the examination of IC-excitation for Sr+ laser.
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Thao, Nguyen Thi Phuong, and Le Sy Vinh. "A Hybrid Approach to Optimize the Number of Recombinations in Ancestral Recombination Graphs." In the 2019 9th International Conference. New York, New York, USA: ACM Press, 2019. http://dx.doi.org/10.1145/3314367.3314385.

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Bresler, Sean, and Michael Heaven. "CESIUM IONIZATION AND RECOMBINATION." In 73rd International Symposium on Molecular Spectroscopy. Urbana, Illinois: University of Illinois at Urbana-Champaign, 2018. http://dx.doi.org/10.15278/isms.2018.fe10.

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Fouquet, J. E. "Recombination Dynamics In Microstructures." In Semiconductor Conferences, edited by Robert R. Alfano. SPIE, 1987. http://dx.doi.org/10.1117/12.940860.

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Hwa, Rudy. ""Recombination in nuclear collisions"." In Workshop on Critical Examination of RHIC Paradigms. Trieste, Italy: Sissa Medialab, 2011. http://dx.doi.org/10.22323/1.111.0004.

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Cacciatore, M., M. Rutigliano, and G. Billing. "Energy flows, recombination coefficients and dynamics for oxygen recombination on silica surfaces." In 7th AIAA/ASME Joint Thermophysics and Heat Transfer Conference. Reston, Virigina: American Institute of Aeronautics and Astronautics, 1998. http://dx.doi.org/10.2514/6.1998-2843.

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Reports on the topic "Recombination"

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Zhang, S. Y., and M. Blaskiewicz. Recombination monitor. Office of Scientific and Technical Information (OSTI), February 2017. http://dx.doi.org/10.2172/1345752.

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Seroussi, E., L. Ma, and G. Liu. Genetic analyses of recombination and PRDM9 alleles and their implications in dairy cattle breeding. Israel: United States-Israel Binational Agricultural Research and Development Fund, 2020. http://dx.doi.org/10.32747/2020.8134158.bard.

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Meiotic recombination is one of the important phenomena contributing to gamete genome diversity. However, it is not well studied in livestock including cattle. The general objectives of this project were to perform genetic analyses of recombination and PRDM9 alleles and study their implications in dairy cattle breeding. The specific objectives were: 1. Analyze variation in recombination across individuals, breeds, and environments; 1.1.Construct individual-level recombination maps; 1.2.Compare recombination features between bulls held under different environmental conditions in US and Israeli; 2. Examine genetic basis of recombination variation in cattle; 2.1.Characterize PRDM9 alleles and their impacts on total and locus-specific recombination features; 2.2.Validate pedigree-based recombination maps using single sperm sequencing and typing; 3. Investigate the impacts of recombination on dairy cattle breeding; 3.1.Evaluate correlation between recombination and dairy production and health traits; 3.2.Evaluate the benefits of incorporating recombination as novel quantitative trait into genomic selection scheme.
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Gregory p. Copenhaver. Regulation of Meiotic Recombination. Office of Scientific and Technical Information (OSTI), November 2011. http://dx.doi.org/10.2172/1028811.

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Gilliland, William, and Michael Rosenbaum. Recombination Calculations by Branch Diagrams. Genetics Society of America Peer-Reviewed Education Portal (GSA PREP), June 2013. http://dx.doi.org/10.1534/gsaprep.2013.002.

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Braun, C. Photoexcited charge pair escape recombination. Office of Scientific and Technical Information (OSTI), November 1989. http://dx.doi.org/10.2172/7257639.

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Continetti, Robert E. Dissociative Recombination Chemistry and Plasma Dynamics. Fort Belvoir, VA: Defense Technical Information Center, June 2008. http://dx.doi.org/10.21236/ada483644.

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Braun, C. L. Photoexcited charge pair escape and recombination. Office of Scientific and Technical Information (OSTI), September 1992. http://dx.doi.org/10.2172/6716679.

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Braun, C. L. Photoexcited charge pair escape and recombination. Office of Scientific and Technical Information (OSTI), November 1991. http://dx.doi.org/10.2172/5942328.

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Arnold, Frances H. Evolution by Structure-Based Protein Recombination. Fort Belvoir, VA: Defense Technical Information Center, June 2003. http://dx.doi.org/10.21236/ada417404.

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Datz, S., P. F. Dittner, C. M. Fou, P. D. Miller, and P. L. Pepmiller. Dielectronic recombination of multiply charged ions. Office of Scientific and Technical Information (OSTI), September 1986. http://dx.doi.org/10.2172/6988274.

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