Academic literature on the topic 'Receptor, IGF Type 2'
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Journal articles on the topic "Receptor, IGF Type 2"
Ballard, F. J., M. Ross, F. M. Upton, and G. L. Francis. "Specific binding of insulin-like growth factors 1 and 2 to the type 1 and type 2 receptors respectively." Biochemical Journal 249, no. 3 (February 1, 1988): 721–26. http://dx.doi.org/10.1042/bj2490721.
Full textRosenzweig, Steven A. "The Continuing Evolution of Insulin-like Growth Factor Signaling." F1000Research 9 (March 23, 2020): 205. http://dx.doi.org/10.12688/f1000research.22198.1.
Full textBallard, F. J., L. C. Read, G. L. Francis, C. J. Bagley, and J. C. Wallace. "Binding properties and biological potencies of insulin-like growth factors in L6 myoblasts." Biochemical Journal 233, no. 1 (January 1, 1986): 223–30. http://dx.doi.org/10.1042/bj2330223.
Full textKim, Jane J., Byung-Chul Park, Yoshiaki Kido, and Domenico Accili. "Mitogenic and Metabolic Effects of Type I IGF Receptor Overexpression in Insulin Receptor-Deficient Hepatocytes." Endocrinology 142, no. 8 (August 1, 2001): 3354–60. http://dx.doi.org/10.1210/endo.142.8.8332.
Full textSchuller, A. G. P., J. W. van Neck, R. W. Beukenholdt, E. C. Zwarthoff, and S. L. S. Drop. "IGF, type I IGF receptor and IGF-binding protein mRNA expression in the developing mouse lung." Journal of Molecular Endocrinology 14, no. 3 (June 1995): 349–55. http://dx.doi.org/10.1677/jme.0.0140349.
Full textWestwood, M. "THE IGF AXIS AT THE FETO-MATERNAL INTERFACE." Reproductive Medicine Review 9, no. 3 (October 2001): 173–96. http://dx.doi.org/10.1017/s096227990100031x.
Full textOguchi, S., W. A. Walker, and I. R. Sanderson. "Differentiation and Polarity Alter the Binding of IGF‐I to Human Intestinal Epithelial (Caco‐2) Cells." Journal of Pediatric Gastroenterology and Nutrition 20, no. 2 (February 1995): 148–55. http://dx.doi.org/10.1002/j.1536-4801.1995.tb11527.x.
Full textShooter, G. K., B. Magee, M. A. Soos, G. L. Francis, K. Siddle, and J. C. Wallace. "Insulin-like growth factor (IGF)-I A- and B-domain analogues with altered type 1 IGF and insulin receptor binding specificities." Journal of Molecular Endocrinology 17, no. 3 (December 1996): 237–46. http://dx.doi.org/10.1677/jme.0.0170237.
Full textHauguel-de Mouzon, S., M. Louizeau, and J. Girard. "Functional alterations of type I insulin-like growth factor receptor in placenta of diabetic rats." Biochemical Journal 288, no. 1 (November 15, 1992): 273–79. http://dx.doi.org/10.1042/bj2880273.
Full textMannucci, Edoardo. "Insulin Therapy and Cancer in Type 2 Diabetes." ISRN Endocrinology 2012 (November 14, 2012): 1–12. http://dx.doi.org/10.5402/2012/240634.
Full textDissertations / Theses on the topic "Receptor, IGF Type 2"
O'Reilly, Kathryn Elizabeth. "Integration of mtor and IGF-1 signaling : feedback upregulation of survival pathways in human cancer cells /." Access full-text from WCMC:, 2007. http://proquest.umi.com/pqdweb?did=1296100571&sid=11&Fmt=2&clientId=8424&RQT=309&VName=PQD.
Full textLuey, Brendan Charles. "Targeting the type 1 IGF receptor in oestrogen-responsive breast cancer." Thesis, University of Newcastle upon Tyne, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.709848.
Full textGodefroy, Anastasia. "Nouvelle stratégie d'enzymothérapie substitutive ciblant le récepteur du mannose 6-phosphate pour les maladies lysosomales." Thesis, Montpellier, 2019. http://www.theses.fr/2019MONTT030.
Full textLysosomal diseases form a heterogeneous group of about fifty rare diseases. At present, only 9 lysosomal diseases have a specific treatment, mainly by enzyme replacement therapy but the beneficial effects appear often limited. The lack of targeting for the Mannose 6-Phosphate Receptor (M6PR), responsible for internalization into the lysosomes, would partly explain this moderate efficiency of the therapeutic enzymes. In this context, we have developed an innovative targeting approach based on Mannose 6-Phosphate Synthetic Analogues Functionalized at the Aglycone position (called AMFAs) to address the unmet needs of current treatments.The work of this thesis focuses mainly on Pompe disease which is a myopathy caused by the deficiency of a lysosomal enzyme, Acid Alpha Glucosidase (GAA), responsible for the conversion of glycogen into glucose. In order to improve the targeting of the therapeutic enzyme to lysosomes via the M6PR, we have functionalized the human recombinant GAA (rhGAA) with the AMFAs. Our studies on aged mice model of the adult form of the disease have demonstrated a significant increase of the enzyme internalization and for the first time, the restoration of muscle health and the significant improvement in motor function (article 1). We then investigated the properties of rhGAA-AMFA. We have proved that the effectiveness of rhGAA-AMFA is not only due to a better cell uptake but also to a more complete intracellular processing of the enzyme (article 2). Indeed, our results demonstrated that in myoblasts of patients affected by Pompe disease there is an overexpression of ACP2 and ACP5 acid phosphatases. These phosphatases can destroy the mannose 6-phosphate signal (M6P) naturally present on the enzyme, therefore possibly interrupting its processing into the active form. AMFA, unlike M6P, is insensitive to this degradation and thus ensures the stability of enzyme addressing in vitro, but also in vivo.All together, these results suggest that the grafting of the AMFAs on recombinant enzymes represents a new therapeutic solution for the treatment of Pompe disease and potentially for other lysosomal diseases
Vincent, Karla Kristine. "Transactivation of Beta 2 Adrenergic Receptor by Bradykinin type 2 Receptor via heterodimerization." Diss., Georgia Institute of Technology, 2009. http://hdl.handle.net/1853/37117.
Full textHower, Amy Elizabeth. "Receptor Functions of the Receptor-Type Protein Tyrosine Phosphatase PTPRO." Scholarly Repository, 2008. http://scholarlyrepository.miami.edu/oa_dissertations/303.
Full textPatel, Dhaval Subhas. "Analysis of the daf-2 insulin/igf-1 receptor gene in Caenorhabditis elegans." Thesis, University College London (University of London), 2006. http://discovery.ucl.ac.uk/1445066/.
Full textHatcher-Solis, Candice N. "PHARMACOLOGICAL IMPLICATIONS OF ADENOSINE 2A RECEPTOR- DOPAMINE TYPE 2 RECEPTOR HETEROMERIZATION." VCU Scholars Compass, 2016. http://scholarscompass.vcu.edu/etd/4458.
Full textPhillips, Timothy Trevor. "A study of metabotropic glutamate receptor type 2." Thesis, University of Cambridge, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.624330.
Full textDE, DOMENICO EMANUELA. "Role of type-2 cannabinoid receptor in reproduction." Doctoral thesis, Università degli Studi di Roma "Tor Vergata", 2016. http://hdl.handle.net/2108/202948.
Full textDaws, Michael Rory. "Hormone responsiveness in breast cancer cell growth : the role of the type I IGF receptor." Thesis, University of Newcastle Upon Tyne, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.284225.
Full textBooks on the topic "Receptor, IGF Type 2"
Flavin, Nora. Cloning and characterisation of the bovine activin receptor type II gene (ActRII): Its localisation to chromosome 2 (BTA2) by somatic cell genetic analysis and the genotyping of an associated microsatelltie UCD2. Dublin: University College Dublin, 1996.
Find full textInternational Symposium on Insulin Action and Its Disorders (1990 Ōtsu-shi, Japan). Recent advances in insulin action and its disorders: Proceedings of the International Symposium on Insulin Action and Its Disorders, Shiga, 16 May 1990. Edited by Shigeta Yukio 1929-, Kobayashi Masashi Dr, and Olefsky Jerrold M. Amsterdam: Excerpta Medica, 1991.
Find full textInternational Symposium on Molecular and Cellular Biology of Insulin and IGFs (3rd 1990 Gainesville, Fla.). Molecular biology and physiology of insulin and insulin-like growth factors. New York: Plenum Press, 1991.
Find full textRainey, Susan. Cloning and characterization of the insulin receptor-related receptor (IRR) reveals that it is closely associated with trkA in the genome and maps to human chromosome 1q22, A type 2 diabetes susceptibility locus. 2002.
Find full textLorent, Kristin. Expression of the Alpha-2-Macroglobulin Receptor System and the Amyloid Precursor Protein Family in Embryos and in Adult Brain of Wild Type and transg: Enic Mice (Acta Biomedica Lovaniensia , No 148). Coronet Books Inc, 1997.
Find full text(Editor), Derek LeRoith, and Mohan K. Raizada (Editor), eds. Molecular Biology and Physiology of Insulin and Insulin-Like Growth Factors (Advances in Experimental Medicine and Biology). Springer, 1991.
Find full textZoccali, Carmine, Davide Bolignano, and Francesca Mallamaci. Left ventricular hypertrophy in chronic kidney disease. Edited by David J. Goldsmith. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199592548.003.0107_update_001.
Full textNielsen, David A., Dmitri Proudnikov, and Mary Jeanne Kreek. The Genetics of Impulsivity. Edited by Jon E. Grant and Marc N. Potenza. Oxford University Press, 2012. http://dx.doi.org/10.1093/oxfordhb/9780195389715.013.0080.
Full textHohmann, Andrea G. Control of pain initiation by endogenous cannabinoids. Edited by Paul Farquhar-Smith, Pierre Beaulieu, and Sian Jagger. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198834359.003.0033.
Full textDilsizian, Vasken, Ines Valenta, and Thomas H. Schindler. Myocardial Viability Assessment. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199392094.003.0021.
Full textBook chapters on the topic "Receptor, IGF Type 2"
Nissley, S. Peter. "Type 2 IGF Receptor-Mediated Events." In The IGF System, 165–97. Totowa, NJ: Humana Press, 1999. http://dx.doi.org/10.1007/978-1-59259-712-3_8.
Full textWerner, Haim. "Molecular Biology of the Type 1 IGF Receptor." In The IGF System, 63–88. Totowa, NJ: Humana Press, 1999. http://dx.doi.org/10.1007/978-1-59259-712-3_4.
Full textChernausek, Steven D., M. Jennifer Abuzzahab, Wieland Kiess, Doreen Osgood, Anke Schneider, and Robert J. Smith. "IGF Resistance: The Role of the Type 1 IGF Receptor." In Deciphering Growth, 121–30. Berlin, Heidelberg: Springer Berlin Heidelberg, 2005. http://dx.doi.org/10.1007/3-540-28902-x_10.
Full textSheikh, Søren Paludan. "Angiotensin Type 2 Receptor." In Encyclopedia of Signaling Molecules, 320–27. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-67199-4_451.
Full textBiswas-Fiss, Esther E., Stephanie Affet, Malissa Ha, Takaya Satoh, Joe B. Blumer, Stephen M. Lanier, Ana Kasirer-Friede, et al. "Angiotensin Type 2 Receptor." In Encyclopedia of Signaling Molecules, 106–13. New York, NY: Springer New York, 2012. http://dx.doi.org/10.1007/978-1-4419-0461-4_451.
Full textMoses, Alan C. "Insulin Resistance and Type 2 Diabetes mellitus: Is There a Therapeutic Role for IGF-1?" In IGF-I and IGF Binding Proteins, 121–34. Basel: KARGER, 2005. http://dx.doi.org/10.1159/000085762.
Full textSandhu, Manjinder S. "Insulin-Like Growth Factor-I and Risk of Type 2 Diabetes and Coronary Heart Disease: Molecular Epidemiology." In IGF-I and IGF Binding Proteins, 44–54. Basel: KARGER, 2005. http://dx.doi.org/10.1159/000085755.
Full textBiswas-Fiss, Esther E., Stephanie Affet, Malissa Ha, Takaya Satoh, Joe B. Blumer, Stephen M. Lanier, Ana Kasirer-Friede, et al. "Angiotensin II Receptor Type 2." In Encyclopedia of Signaling Molecules, 106. New York, NY: Springer New York, 2012. http://dx.doi.org/10.1007/978-1-4419-0461-4_100061.
Full textvan Roy, Frans, Volker Nimmrich, Anton Bespalov, Achim Möller, Hiromitsu Hara, Jacob P. Turowec, Nicole A. St. Denis, et al. "C-Type Mannose Receptor 2." In Encyclopedia of Signaling Molecules, 481. New York, NY: Springer New York, 2012. http://dx.doi.org/10.1007/978-1-4419-0461-4_100327.
Full textGewies, Andreas, Jürgen Ruland, Alexey Kotlyarov, Matthias Gaestel, Shiri Procaccia, Rony Seger, Shin Yasuda, et al. "Mannose Receptor, C-type 2." In Encyclopedia of Signaling Molecules, 1042. New York, NY: Springer New York, 2012. http://dx.doi.org/10.1007/978-1-4419-0461-4_100743.
Full textConference papers on the topic "Receptor, IGF Type 2"
Bid, Hemant K., Doris Phelps, and Peter J. Houghton. "Abstract 3277: Insulin-like growth factor-2 (IGF-2) circumvents the antiangiogenic activity of SCH717454, a human antibody that blocks ligand binding to the Type 1 insulin-like growth factor receptor (IGF-1R)." In Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1538-7445.am2011-3277.
Full textDelain, E., M. Barrav, J. Tapon-Bretaudière, F. Pochon, and F. Van Leuven. "THE MOLECULAR ORGANIZATION OF HUMAN ALPHA 2-MACROGLOBULIN. AN IMMUNO ELECTRON MICROSCOPIC STUDY WITH MONOCLONAL ANTIBODIES." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643864.
Full textZeng, X., D. Sachdev, H. Zhang, and D. Yee. "Sequencing of type I IGF receptor (IGF1R) inhibition affects chemotherapy response in vitro and in vivo." In CTRC-AACR San Antonio Breast Cancer Symposium: 2008 Abstracts. American Association for Cancer Research, 2009. http://dx.doi.org/10.1158/0008-5472.sabcs-3122.
Full textZanarel, Palomali, Marina Grigoli, Danielle de Oliveira, Patrícia Manzine, and Márcia Cominetti. "IFG-1 PLASMA LEVELS ARE ALTERED IN PATIENTS WITH ALZHEIMER’S DIASEASE AND DIABTES MELLITUS TYPE 2." In XIII Meeting of Researchers on Alzheimer's Disease and Related Disorders. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1980-5764.rpda045.
Full textGoldblatt, D. L., A. Fouts, G. Valverde-Ha, M. Martinez-Moczygemba, D. Huston, M. J. Tuvim, B. F. Dickey, and S. E. Evans. "Aerosolized Toll-Like Receptor Agonists Modulate Type 2 Allergic Inflammation." In American Thoracic Society 2021 International Conference, May 14-19, 2021 - San Diego, CA. American Thoracic Society, 2021. http://dx.doi.org/10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a1347.
Full textGalet, Colette, Ashley Gray, R. James Barnard, Brandon Castor, Junxiang Wan, Jonathan Said, Pedro Beltran, Franck Calzone, Pinchas Pinchas Cohen, and William J. Aronson. "Abstract LB-458: Additive effects of caloric restriction and IGF-I receptor blockade on the progression of 22RV1 prostate cancer xenografts." In Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1538-7445.am2011-lb-458.
Full textKertels, O., M. Breun, H. Hänscheid, M. Kircher, P. Hartrampf, A. Schirbel, CM Monoranu, et al. "Peptide Receptor Radionuclide Therapy in Patients with Neurofibromatosis Type 2 – Initial Experience." In NuklearMedizin 2020. © Georg Thieme Verlag KG, 2020. http://dx.doi.org/10.1055/s-0040-1708361.
Full textBoss, M., L. Deden, M. Brom, S. van Lith, and M. Gotthardt. "Pituitary GLP-1 receptor expression in the pathophysiology of type 2 diabetes." In NuklearMedizin 2019. Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-1683647.
Full textAdachi, Yasushi, Hiroyuki Yamamoto, Masanori Ii, Hua Li, Hirokazu Ohashhi, Yoshiaki Arimura, Takao Endo, Kohzoh Imai, David P. Carbone, and Yasushisa Shinomura. "Abstract 632: The efficacy of IGF-I receptor monoclonal antibody for human gastrointestinal carcinomas is independent for mutation status of k-ras." In Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1538-7445.am2011-632.
Full textDaigle, Noelle, Thomas G. Knapp, Suzann Duan, David W. Jones, Ali Azhdarinia, Sukhen C. Ghosh, Solmaz AghaAmiri, et al. "Combined multiphoton microscopy and somatostatin receptor type 2 imaging of pancreatic neuroendocrine tumors." In Multimodal Biomedical Imaging XVIII, edited by Fred S. Azar, Xavier Intes, and Qianqian Fang. SPIE, 2023. http://dx.doi.org/10.1117/12.2648113.
Full textReports on the topic "Receptor, IGF Type 2"
Funkenstein, Bruria, and Cunming Duan. GH-IGF Axis in Sparus aurata: Possible Applications to Genetic Selection. United States Department of Agriculture, November 2000. http://dx.doi.org/10.32747/2000.7580665.bard.
Full textPlymate, Stephen R. Therapy of Prostate Cancer Using a Human Antibody Targeting the Type 1 Insulin-Like Growth Factor Receptor (IGF-IR). Fort Belvoir, VA: Defense Technical Information Center, September 2009. http://dx.doi.org/10.21236/ada524529.
Full textMeidan, Rina, and Robert Milvae. Regulation of Bovine Corpus Luteum Function. United States Department of Agriculture, March 1995. http://dx.doi.org/10.32747/1995.7604935.bard.
Full textZhuo, Chuanjun, Hongjun Tian, Lina Wang, Xiangyang Gao, Li Ding, and Ming Liu. Comparative safety of glucagon like peptide‑1 receptor agonists in patients with type 2 diabetes: a network meta-analysis of cardiovascular outcome trials. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, August 2020. http://dx.doi.org/10.37766/inplasy2020.8.0122.
Full textMeidan, Rina, and Joy Pate. Roles of Endothelin 1 and Tumor Necrosis Factor-A in Determining Responsiveness of the Bovine Corpus Luteum to Prostaglandin F2a. United States Department of Agriculture, January 2004. http://dx.doi.org/10.32747/2004.7695854.bard.
Full textHansen, Peter J., and Amir Arav. Embryo transfer as a tool for improving fertility of heat-stressed dairy cattle. United States Department of Agriculture, September 2007. http://dx.doi.org/10.32747/2007.7587730.bard.
Full textDeo, Salil, David McAllister, Naveed Sattar, and Jill Pell. The time-varying cardiovascular benefits of glucagon like peptide-1 agonist (GLP-RA)therapy in patients with type 2 diabetes mellitus: A meta-analysis of multinational randomized trials. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, July 2021. http://dx.doi.org/10.37766/inplasy2021.7.0097.
Full textZhang, Mingzhu, Wujisiguleng Bao, Luying Sun, Zhi Yao, and Xiyao Li. Efficacy and safety of finerenone in chronic kidney disease associated with type 2 diabetes: meta-analysis of randomized clinical trials. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, March 2022. http://dx.doi.org/10.37766/inplasy2022.3.0020.
Full textyu, luyou, jinping yang, xi meng, and yanhua lin. Effectiveness of the gut microbiota-bile acid pathway (BAS) in the treatment of Type 2 diabetes: A protocol for systematic review and meta analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, July 2022. http://dx.doi.org/10.37766/inplasy2022.7.0117.
Full textSisler, Edward C., Raphael Goren, and Akiva Apelbaum. Controlling Ethylene Responses in Horticultural Crops at the Receptor Level. United States Department of Agriculture, October 2001. http://dx.doi.org/10.32747/2001.7580668.bard.
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