Journal articles on the topic 'Reactivation of vulnerabilities'
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Singh, Navneet, Lindsey Romick-Rosendale, Miki Watanabe-Chailland, Lisa M. Privette Vinnedge, and Kakajan Komurov. "Drug resistance mechanisms create targetable proteostatic vulnerabilities in Her2+ breast cancers." PLOS ONE 17, no. 12 (December 8, 2022): e0256788. http://dx.doi.org/10.1371/journal.pone.0256788.
Full textDelgado-Goñi, Teresa, Teresa Casals Galobart, Slawomir Wantuch, Deimante Normantaite, Martin O. Leach, Steven R. Whittaker, and Mounia Beloueche-Babari. "Increased inflammatory lipid metabolism and anaplerotic mitochondrial activation follow acquired resistance to vemurafenib in BRAF-mutant melanoma cells." British Journal of Cancer 122, no. 1 (December 10, 2019): 72–81. http://dx.doi.org/10.1038/s41416-019-0628-x.
Full textLupien, Leslie, Veronica Rendo, Eric Morin, Nicholas Khuu, Jeromy DiGiacomo, Prasidda Khadka, Madison Chacon, et al. "DIPG-54. p53 pathway reactivation as a therapeutic strategy in diffuse intrinsic pontine glioma." Neuro-Oncology 24, Supplement_1 (June 1, 2022): i31. http://dx.doi.org/10.1093/neuonc/noac079.111.
Full textGarcia-Lopez, Jesus, Shiekh Tanveer Ahmad, Yiran Li, Brian Gudenas, Marija Kojic, Friedrik Manz, Barbara Jonchere, et al. "MDB-23. ELP1 GERMLINE DEFICIENCY SENSITIZES THE GRANULE NEURON LINEAGE TO SHH MEDULLOBLASTOMA AND EXPOSES NOVEL THERAPEUTIC VULNERABILITIES." Neuro-Oncology 25, Supplement_1 (June 1, 2023): i67. http://dx.doi.org/10.1093/neuonc/noad073.255.
Full textSchaub, Franz X., Weimin Li, Mohammad Fallahi, Chunying Yang, Stephanie K. Schaub, Soyoung Lee, Alexandar Tzankov, Clemens Schmitt, Antonio L. Amelio, and John L. Cleveland. "Myc-Directed Suppression of Autophagy Provides Therapeutic Vulnerabilities Targeting Amino Acid Homeostasis." Blood 126, no. 23 (December 3, 2015): 2450. http://dx.doi.org/10.1182/blood.v126.23.2450.2450.
Full textWatson, Sarah, Collette A. LaVigne, Lin Xu, Didier Surdez, Joanna Cyrta, Delia Calderon, Matthew V. Cannon, et al. "Abstract 3525: VGLL2-NCOA2 leverages developmental programs for pediatric sarcomagenesis." Cancer Research 83, no. 7_Supplement (April 4, 2023): 3525. http://dx.doi.org/10.1158/1538-7445.am2023-3525.
Full textHass, Ralf, Juliane von der Ohe, and Hendrik Ungefroren. "The Intimate Relationship among EMT, MET and TME: A T(ransdifferentiation) E(nhancing) M(ix) to Be Exploited for Therapeutic Purposes." Cancers 12, no. 12 (December 7, 2020): 3674. http://dx.doi.org/10.3390/cancers12123674.
Full textLi, Chendi, Qian Qin, Mohammed Usman Syed, Anahita Nimbalkar, Barbara Karakyriakou, Sarah E. Clark, Anne Y. Saiki, et al. "Abstract 3867: Chromatin modification driving sub-clonal resistance to KRAS G12C combination therapies in KRAS mutant non-small cell lung cancer." Cancer Research 83, no. 7_Supplement (April 4, 2023): 3867. http://dx.doi.org/10.1158/1538-7445.am2023-3867.
Full textNagel, Stefan, Claudia Pommerenke, Corinna Meyer, Roderick A. F. MacLeod, and Hans G. Drexler. "Establishment of the TALE-code reveals aberrantly activated homeobox gene PBX1 in Hodgkin lymphoma." PLOS ONE 16, no. 2 (February 4, 2021): e0246603. http://dx.doi.org/10.1371/journal.pone.0246603.
Full textSaha, Ananya, and Narendra M. Dixit. "Pre-existing resistance in the latent reservoir can compromise VRC01 therapy during chronic HIV-1 infection." PLOS Computational Biology 16, no. 11 (November 30, 2020): e1008434. http://dx.doi.org/10.1371/journal.pcbi.1008434.
Full textPrasetyo, Aan Aji. "INTERNALISASI HADIS KASIH SAYANG DALAM MEWUJUDKAN SOCIAL INTEREST DI ERA DISRUPSI." Jurnal Studi Ilmu-ilmu Al-Qur'an dan Hadis 21, no. 1 (January 30, 2020): 217. http://dx.doi.org/10.14421/qh.2020.2101-11.
Full textMartin, Matthew J., Nicolas Floc'h, Matthias Pfeifer, Steven Criscione, Oona Delpuech, Sladjana Gagrica, Yi Yao, Ultan McDermott, and Paul D. Smith. "Pharmaceutical reactivation of attenuated apoptotic pathways leads to elimination of osimertinib drug tolerant cells." Cancer Research Communications, September 12, 2022. http://dx.doi.org/10.1158/2767-9764.crc-22-0066.
Full textSciacovelli, Marco, Aurelien Dugourd, Lorea Valcarcel Jimenez, Ming Yang, Efterpi Nikitopoulou, Ana S. H. Costa, Laura Tronci, et al. "Dynamic partitioning of branched-chain amino acids-derived nitrogen supports renal cancer progression." Nature Communications 13, no. 1 (December 20, 2022). http://dx.doi.org/10.1038/s41467-022-35036-4.
Full textMisek, Sean A., Bardees M. Foda, Thomas S. Dexheimer, Maisah Akram, Susan E. Conrad, Jens C. Schmidt, Richard R. Neubig, and Kathleen A. Gallo. "BRAF Inhibitor Resistance Confers Increased Sensitivity to Mitotic Inhibitors." Frontiers in Oncology 12 (April 4, 2022). http://dx.doi.org/10.3389/fonc.2022.766794.
Full textRolling, Julie, Guillaume Corduan, Martin Roth, Carmen M. Schroder, and Amaury C. Mengin. "Violent Radicalization and Post-traumatic Dissociation: Clinical Case of a Young Adolescent Girl Radicalized." Frontiers in Psychiatry 13 (March 22, 2022). http://dx.doi.org/10.3389/fpsyt.2022.793291.
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