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Journal articles on the topic 'Raynaud's'

Author: Grafiati

Published: 4 June 2021

Last updated: 14 February 2022

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1

Devgire, Vikrant, and Michael Hughes. "Raynaud's phenomenon." British Journal of Hospital Medicine 80, no. 11 (November 2, 2019): 658–64. http://dx.doi.org/10.12968/hmed.2019.80.11.658.

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Raynaud's phenomenon is a common vasospastic condition which carries a significant burden of pain and hand-related disability ( Hughes and Herrick, 2016 ). The prevalence of Raynaud's phenomenon in the general population has been reported to be approximately 5% ( Garner et al, 2015 ). Raynaud's phenomenon can occur either as a primary (‘idiopathic’) phenomenon or secondary to a wide range of underlying medical conditions and drug causes. Therefore, hospital-based specialists are frequently involved in the care of patients with Raynaud's phenomenon and need to be aware of associated conditions and prescribed medications for Raynaud's phenomenon. In particular, Raynaud's phenomenon is often the earliest manifestation of an underlying autoimmune connective tissue disease (e.g. systemic sclerosis). A comprehensive clinical assessment is required including performing targeted investigations (e.g. nailfold capillaroscopy and systemic sclerosis-associated autoantibodies). Patient education and lifestyle adaptations is first-line treatment for Raynaud's phenomenon. There is a wide range of pharmacological options including oral and intravenous drug therapies available to treat Raynaud's phenomenon. Surgical intervention is sometimes required for refractory Raynaud's phenomenon and tissue ischaemia. This review describes the clinical manifestations of Raynaud's phenomenon including potential secondary causes and presents an approach to assessment and management.

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2

Haque, Ashraful, and Michael Hughes. "Raynaud's phenomenon." Clinical Medicine 20, no. 6 (November 2020): 580–87. http://dx.doi.org/10.7861/clinmed.2020-0754.

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3

Hughes, Michael, and Ariane L. Herrick. "Raynaud's phenomenon." Best Practice & Research Clinical Rheumatology 30, no. 1 (February 2016): 112–32. http://dx.doi.org/10.1016/j.berh.2016.04.001.

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4

Herrick, Ariane L., and Fredrick M. Wigley. "Raynaud's phenomenon." Best Practice & Research Clinical Rheumatology 34, no. 1 (February 2020): 101474. http://dx.doi.org/10.1016/j.berh.2019.101474.

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5

Belch, J. "Raynaud's phenomenon." Cardiovascular Research 33, no. 1 (January 1997): 25–30. http://dx.doi.org/10.1016/s0008-6363(96)00183-6.

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6

Block, Joel A., and Winston Sequeira. "Raynaud's phenomenon." Lancet 357, no. 9273 (June 2001): 2042–48. http://dx.doi.org/10.1016/s0140-6736(00)05118-7.

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7

Wigley, Fredrick M. "Raynaud's Phenomenon." New England Journal of Medicine 347, no. 13 (September 26, 2002): 1001–8. http://dx.doi.org/10.1056/nejmcp013013.

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8

Dowd, PaulineM, PortiaC Goldsmith, HelenA Bull, Geoffrey Burnstock, JohnC Foreman, and Ian Marshall. "Raynaud's phenomenon." Lancet 346, no. 8970 (July 1995): 283–90. http://dx.doi.org/10.1016/s0140-6736(95)92169-9.

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9

A., Michael. "RAYNAUD'S SYNDROME." ANZ Journal of Surgery 63, no. 2 (February 1993): 162. http://dx.doi.org/10.1111/j.1445-2197.1993.tb00074.x.

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10

Pearce, J. "Raynaud's phenomenon." Journal of Neurology, Neurosurgery & Psychiatry 52, no. 5 (May 1, 1989): 594. http://dx.doi.org/10.1136/jnnp.52.5.594.

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11

Cooke, E. D., and A. N. Nicolaides. "Raynaud's syndrome." BMJ 300, no. 6724 (March 3, 1990): 553–55. http://dx.doi.org/10.1136/bmj.300.6724.553.

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12

Challenor, V. F., K. Donaldson, and D. G. Waller. "Raynaud's syndrome." BMJ 300, no. 6730 (April 14, 1990): 1015–16. http://dx.doi.org/10.1136/bmj.300.6730.1015-b.

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13

Freedman, R. R. "Raynaud's syndrome." BMJ 300, no. 6732 (April 28, 1990): 1138. http://dx.doi.org/10.1136/bmj.300.6732.1138-a.

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14

McGrath, Anne. "Raynaud's Syndrome." American Journal of Nursing 97, no. 1 (January 1997): 34. http://dx.doi.org/10.1097/00000446-199701000-00029.

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15

Wigley, Fredrick M., and Nicholas A. Flavahan. "RAYNAUD'S PHENOMENON." Rheumatic Disease Clinics of North America 22, no. 4 (November 1996): 765–81. http://dx.doi.org/10.1016/s0889-857x(05)70300-8.

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16

Bowling, JCR, and PM Dowd. "Raynaud's disease." Lancet 361, no. 9374 (June 2003): 2078–80. http://dx.doi.org/10.1016/s0140-6736(03)13646-x.

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17

O'Connor, Carmen Michelle. "Raynaud's phenomenon." Journal of Vascular Nursing 19, no. 3 (September 2001): 87–93. http://dx.doi.org/10.1067/mvn.2001.117786.

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18

Klippel, John H. "Raynaud's Phenomenon." Archives of Internal Medicine 151, no. 12 (December 1, 1991): 2389. http://dx.doi.org/10.1001/archinte.1991.00400120035006.

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19

TURNIPSEED, WILLIAM D. "Raynaud's Syndrome." Archives of Surgery 127, no. 4 (April 1, 1992): 488. http://dx.doi.org/10.1001/archsurg.1992.01420040134025.

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20

Edwards, James M. "Raynaud's Syndrome." Annals of Vascular Surgery 8, no. 5 (September 1994): 509–13. http://dx.doi.org/10.1007/bf02133074.

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21

GARLAND, G. M. "RAYNAUD'S DISEASE." JAMA: The Journal of the American Medical Association 262, no. 23 (December 15, 1989): 3290. http://dx.doi.org/10.1001/jama.1989.03430230073028.

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22

Nuttall, Dilyse. "Raynaud's phenomenon." Nurse Prescribing 15, no. 8 (August 2, 2017): 376. http://dx.doi.org/10.12968/npre.2017.15.8.376.

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23

Wouda, A. A. "Raynaud's Phenomenon." Acta Medica Scandinavica 201, no. 1-6 (April 24, 2009): 519–23. http://dx.doi.org/10.1111/j.0954-6820.1977.tb15740.x.

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24

Burns, E. C., D. B. Dunger, and M. J. Dillon. "Raynaud's disease." Archives of Disease in Childhood 60, no. 6 (June 1, 1985): 537–41. http://dx.doi.org/10.1136/adc.60.6.537.

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25

Marcus, Stanley, Steven R. Weiner, Sharon M. Suzuki, and Luz Kwan. "Raynaud's syndrome." Postgraduate Medicine 89, no. 4 (March 1991): 171–87. http://dx.doi.org/10.1080/00325481.1991.11700870.

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26

Yao, James S. T. "Raynaud's syndrome." Journal of Vascular Surgery 15, no. 3 (March 1992): 588–89. http://dx.doi.org/10.1016/0741-5214(92)90208-p.

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27

Blaschke, F. "Raynaud's disease." Biomedicine & Pharmacotherapy 48, no. 3-4 (January 1994): 176. http://dx.doi.org/10.1016/0753-3322(94)90111-2.

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28

Gayraud, Martine. "Raynaud's phenomenon." Joint Bone Spine 74, no. 1 (January 2007): e1-e8. http://dx.doi.org/10.1016/j.jbspin.2006.07.002.

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29

Kviecinskas, Giedrius, Artūras Razbadauskas, and Rimvydas Gutauskas. "Raynaud fenomenas: ankstyvieji chirurginio gydymo rezultatai." Lietuvos chirurgija 2, no. 1 (January 1, 2004): 0. http://dx.doi.org/10.15388/lietchirur.2004.1.2379.

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Giedrius Kviecinskas1, Artūras Razbadauskas2, Rimvydas Gutauskas21 Klaipėdos jūrininkų ligoninės Chirurgijos klinika,Liepojos pl. 45, LT-5809 KlaipėdaEl paštas: kviecing@takas.lt2 Klaipėdos universitetas,H. Manto g. 84, LT-5800 KlaipėdaKlaipėdos jūrininkų ligoninės Chirurgijos klinika,Liepojos pl. 45, LT-5809 Klaipėda Įvadas / tikslas Teigiama, kad Raynaud fenomenas būdingas apie 22% pasaulio žmonių. Moterims jis pasitaiko penkis kartus dažniau nei vyrams. Darbo tikslas – išsiaiškinti Raynaud fenomeno chirurginio gydymo ankstyvuosius rezultatus. Metodas Darbo pobūdis retrospektyvus. Nagrinėtos 1997–2003 m. Klaipėdos jūrininkų ligoninėje nuo Raynaud sindromo gydytų ligonių, kuriems buvo atliktos krūtininės simpatektomijos, ligos istorijos ir ambulatorinės kortelės. Naudojant šalčio mėginį, lyginti priešoperaciniai duomenys ir ankstyvieji krūtinės simpatektomijos rezultatai. Šalčio mėginys – tai kraujo įsotinimo deguonimi matavimas didžiajame rankos piršte, palaikius plaštaką penkias minutes +2, +3 °C temperatūros tekančiame vandenyje. Nustatant operacijos indikacijas atsižvelgta į ligos trukmę, gretutines ligas. Ligoniai tirti ieškant galimo krūtinės atvaros sindromo, taip pat jiems atlikta žvaigždinio mazgo blokada. Rezultatai 1997–2003 metais Klaipėdos jūrininkų ligoninėje 22 ligoniams atliktos 23 torakalinės simpatektomijos operacijos. Visiems jiems prieš operaciją ir antrą pooperacinę parą atliktas šalčio mėginys, siekiant įvertinti operacijos veiksmingumą. Atliekant šalčio mėginį prieš operaciją, kraujo įsotinimas deguonimi buvo neišmatuojamas ir pasiekdavo normalią ribą (95–99% SaO2) po 30–36 minučių. Antrą pooperacinę parą kraujo įsotinimas deguonimi sunormalėdavo per 1–2 minutes. Išvados Tyrimai rodo, kad chirurgiškai gydant Raynaud fenomeną, gaunami geri rezultatai ankstyvuoju pooperaciniu laikotarpiu. Prasminiai žodžiai: Raynaud fenomenas, torakalinė simpatektomija, mažai invazyvi chirurgija, saturacija The Raynaud phenomenon: early results of surgical treatment Giedrius Kviecinskas1, Artūras Razbadauskas2, Rimvydas Gutauskas2 Background / Objective The Raynaud disease phenomenon is found in about 22% of the world's population. This syndrome affects women more frequently than men. The study reports on the effectivity of thoracic sympathectomy in 1997–2003. This effectivity was valuated by a new method – oxygen saturation repair after "cold test" in the middle finger of the operated on side. Methods This work is a retrospective survey of the investigation and treatment of patients with Raynaud syndrome. We established the indications of the surgical treatment of Raynaud's phenomenon. The "cold test" was employed to observe short-term results of this treatment. The "cold test" is the measurement of O2 saturation in the middle finger of the hand after keeping it for 5 minutes in water at (+2)–(+3) C. The "cold test" was used to test patients before operation and on the second postoperative day after thoracic sympathectomy. To determine the indications of surgical treatment, we considered the concomitant diseases and the duration of Raynaud's phenomenon. The patients were investigated for the possibility of thoracic outlet syndrome. Before surgery, for all patients the ganglion stellatum blockade was performed. Results During 1997–2003, 23 sympathectomies for 22 patients were performed. All patients were tested with the "cold method" before surgery and on the second postoperative day. Before operation, O2 saturation was unmeasurable and restored till the normal range after 30–36 minutes. On the second postoperative day the saturation was unmeasurable too, but it restored to the normal range in 1–2 minutes. Conclusions The surgical treatment of Raynaud's phenomenon is effective in a short postoperative period. The "cold method" is effective for evaluating effectivity of thoracic sympathectomy. Keywords: Raynaud's phenomenon, thoracic sympathectomy, minimal invasive surgery, saturation

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30

Generali, Joyce, and Dennis J. Cada. "Fluoxetine: Raynaud's Phenomenon." Hospital Pharmacy 37, no. 6 (June 2002): 601–9. http://dx.doi.org/10.1177/001857870203700613.

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Off-Label Drug Uses This Hospital Pharmacy feature is extracted from Off-Label DrugFacts, a quarterly publication available from Facts and Comparisons. Off-Label DrugFacts is a practitioner-oriented resource for information about specific FDA-unapproved drug uses. This new guide to the literature will enable the health care professional/clinician to quickly identify published studies on off-label uses and to determine if a specific use is rational in a patient care scenario. The most relevant data are provided in tabular form so that the reader can easily identify the scope of information available. A summary of the data–including, background, study design, patient population, dosage information, therapy duration, results, safety, and therapeutic considerations–precedes each table of published studies. References direct the reader to the full literature for more comprehensive information prior to patient care decisions. Direct questions or comments on “Off-Label Drug Uses” to hospitalpharmacy@drugfacts.com .

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31

Katada, Yoshinori, and Toshio Tanaka. "Lingual Raynaud's Phenomenon." New England Journal of Medicine 366, no. 7 (February 16, 2012): e12. http://dx.doi.org/10.1056/nejmicm1104140.

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32

Rodgers, Michael. "Primary Raynaud's Phenomenon." New England Journal of Medicine 368, no. 14 (April 4, 2013): 1344. http://dx.doi.org/10.1056/nejmicm1209600.

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33

Roath, S. "Managing Raynaud's phenomenon." BMJ 293, no. 6539 (July 12, 1986): 88–89. http://dx.doi.org/10.1136/bmj.293.6539.88.

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34

Lafferty, K., and L. T. Cotton. "Managing Raynaud's phenomenon." BMJ 293, no. 6545 (August 23, 1986): 508. http://dx.doi.org/10.1136/bmj.293.6545.508.

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35

Planchon, Bernard, Marc-Antoine Pistorius, Philippe Beurrier, and Philippe De Faucal. "Primary Raynaud's Phenomenon." Angiology 45, no. 8 (August 1994): 677–86. http://dx.doi.org/10.1177/000331979404500802.

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36

Taillan, B., J. Castanet, G. Garnier, A. Pesce, F. Sanderson, J. G. Fuzibet, and P. Dujardin. "Paraneoplastic Raynaud's phenomenon." Clinical Rheumatology 12, no. 2 (June 1993): 281–82. http://dx.doi.org/10.1007/bf02231545.

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37

Decross, Arthur J., and Deepak M. Sahasrabudhe. "Paraneoplastic Raynaud's phenomenon." American Journal of Medicine 92, no. 5 (May 1992): 571–72. http://dx.doi.org/10.1016/0002-9343(92)90758-4.

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38

Colakoğlu, Murat, Veli Cobankara, and Tekin Akpolat. "Effect of Clonazepam on Raynaud's Phenomenon and Fingertip Ulcers in Scleroderma." Annals of Pharmacotherapy 41, no. 9 (September 2007): 1544–47. http://dx.doi.org/10.1345/aph.1k212.

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Objective: To report the novel finding of a significant improvement in Raynaud's phenomenon symptoms with clonazepam in a patient with systemic sclerosis. Case Summary: A 45-year-old female with limited scleroderma and chronic renal failure was admitted to our hospital due to hyponatremia (sodium 103 mEq/L). Her hyponatremia was treated by intravenous infusion of NaCI 3%. Clonazepam, which had been prescribed previously for anxiety and insomnia, was discontinued. Three weeks after she was discharged from the hospital, the patient presented with the complaint of increased severity of Raynaud's phenomenon and digital ulcers. She told us that her fingertip ulcers had been healed while she was taking clonazepam and that episodes of Raynaud's phenomenon had increased after discontinuation of the drug. Clonazepam 1 mg twice daily was restarted, and Raynaud's phenomenon and fingertip ulcers resolved within a month. On 2 occasions after that time, we discontinued clonazepam and replaced it with alprazolam, as the patient believed alprazolam was more beneficial in alleviating anxiety. Episodes of Raynaud's phenomenon and new digital ulcers recurred on both of these occasions, and clonazepam was restarted. At the time of writing, no severe episodes of Raynaud's phenomenon or fingertip ulcers have occurred with clonazepam treatment. Discussion: Raynaud's phenomenon and recurrent digital ulcers are a manifestation of vascular disease in patients with systemic sclerosis and lead to pain, impaired function, and tissue loss. Few drugs have previously been shown to affect digital ulcers in the setting of scleroderma. Our patient experienced a significant and sustained improvement in Raynaud's phenomenon and digital ulcers following the initiation of clonazepam. To our knowledge, as of March 2007, this is the first reported use of clonazepam in Raynaud's phenomenon and digital ulcer. While its therapeutic mechanism remains unclear, clonazepam may offer some advantages compared with current agents. Conclusions: We report a case of Raynaud's phenomenon and digital ulcers responding to clonazepam. Further research is warranted to test the robustness of this preliminary finding.

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39

Riccio, A., M. G. Sangiolo, and G. Tarantino. "Synchronous Onset of Secondary Raynaud's Phenomenon in Monozygotic Twins." European Journal of Inflammation 10, no. 3 (September 2012): 535–37. http://dx.doi.org/10.1177/1721727x1201000331.

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The heritability of primary Raynaud's phenomenon has been reported in previous works. In this paper we describe the simultaneous onset of Raynaud's phenomenon, rapidly evolved in acrocyanosis and diagnosed as secondary Raynaud's phenomenon, observed in monozygotic twins. This case supports the role of genetic factors in the pathogenesis of such disorder. Moreover, the singular synchronism of its appearance is discussed.

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40

Hottenga, JJ, KRJ Vanmolkot, EE Kors, S. Kheradmand Kia, PTVM de Jong, J. Haan, GM Terwindt, RR Frants, MD Ferrari, and AMJM van den Maagdenberg. "The 3p21.1-p21.3 Hereditary Vascular Retinopathy Locus Increases the Risk for Raynaud's Phenomenon and Migraine." Cephalalgia 25, no. 12 (December 2005): 1168–72. http://dx.doi.org/10.1111/j.1468-2982.2005.00994.x.

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Previously, we described a large Dutch family with hereditary vascular retinopathy (HVR), Raynaud's phenomenon and migraine. A locus for HVR was mapped on chromosome 3p21.1-p21.3, but the gene has not yet been identified. The fact that all three disorders share a vascular aetiology prompted us to study whether the HVR haplotype also contributed to Raynaud's phenomenon and migraine in this family. Whereas the parent-child transmission disequilibrium test (TDT) did not reach significance, the sibling TDT revealed that the HVR haplotype harbours a susceptibility factor for Raynaud's phenomenon and migraine. Identification of the HVR gene will improve the understanding of the pathophysiology of HVR, Raynaud's phenomenon and migraine.

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41

Morino, Carolyn, and Susan M. Winn. "Raynaud's Phenomenon of the Nipples: An Elusive Diagnosis." Journal of Human Lactation 23, no. 2 (May 2007): 191–93. http://dx.doi.org/10.1177/0890334407300018.

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Pain and throbbing of the nipples associated with Raynaud's phenomenon often mimics yeast or fungal infections. Breastfeeding mothers with Raynaud's of the nipples are often treated inappropriately for organisms such as Candida Albicans with topical or systemic antifungal agents. This case report describes the eventual diagnosis of Raynaud's phenomenon of the nipples in a breastfeeding mother who was initially treated for yeast. J Hum Lact. 23(2):191-193.

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42

Gerbracht, David D., Virginia D. Steen, Gayle L. Ziegler, Thomas A. Medsger, and Gerald P. Rodnan. "Evolution of primary raynaud's phenomenon (raynaud's disease) to connective tissue disease." Arthritis & Rheumatism 28, no. 1 (January 1985): 87–92. http://dx.doi.org/10.1002/art.1780280114.

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43

Cooke, John P., Shelly J. Creager, Kathleen M. Scales, Christine Ren, Nicholas P. Tsapatsaris, William P. Beetham, and Mark A. Creager. "Role of Digital Artery Adrenoceptors in Raynaud's Disease." Vascular Medicine 2, no. 1 (February 1997): 1–7. http://dx.doi.org/10.1177/1358863x9700200101.

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Raynaud's disease is characterized by excessive cutaneous vasoconstriction in response to ambient cold. A functional disturbance in the local regulation of digital vasomotion has been proposed. The purpose of this study was to determine whether there is an alteration in the postjunctional adrenergic receptors in the digital circulation of patients with Raynaud's disease. Furthermore, we sought to determine whether this abnormality was responsible for the excessive cold-induced vasoconstriction in these patients. Finger blood flow was measured by strain-gauge venous occlusion plethysmography in 10 patients with Raynaud's disease and in 10 normal volunteers in a 22 °C room. Measurements of finger blood flow and mean systemic arterial pressure were made during intra-arterial infusions of the alpha1-adrenergic antagonist, prazosjn, or the alpha2-adrenergic antagonist, yohimbine, at room temperature and during local cooling of the hand. Basal finger blood flow in normal subjects was significantly greater than that of patients (8.6 ± 2.7 vs 1.7 ± 0.5 ml/100 ml per min; normal vs Raynaud's subjects; p < 0.05). In normal subjects, either prazosin or yohimbine induced dose-dependent increases in finger blood flow. The maximal increase in finger blood flow induced by prazosin was significantly greater than that in response to yohimbine (29.2 ± 10.1 vs 2.8 ± 2.1 ml/100 ml per min; prazosin vs yohimbine; p < 0.05). By contrast, in the Raynaud's patients, prazosin or yohimbine induced maximal increases in finger blood flow that were not significant (7.1 ± 1.8 vs 5.0 ± 2.2 ml/100 ml per min; prazosin vs yohimbine; p = NS). The response to prazosin in Raynaud's patients was significantly less than that of the normal volunteers ( p < 0.05). In normal subjects, during intra-arterial infusion of vehicle alone, cooling induced a 52.6 ± 5.8% reduction in finger blood flow. This cold-induced vasoconstriction was blunted, but not qualitatively altered, by either adrenergic antagonist. In the Raynaud's patients, during the intra-arterial infusion of the vehicle, cooling induced a 68.2 ± 7.8% reduction in finger blood flow. Infusion of either adrenergic antagonist blunted, but did not qualitatively alter, the response to cold. Finger blood flow is less in patients with Raynaud's disease than in normal subjects when studied in a 22 °C room. In normal subjects, postjunctional alpha1-adrenergic receptors appear to predominate in the control of digital vasoconstriction. Postjunctional alpha1- and alpha2- adrenoceptors play an equal role in adrenergic regulation of finger blood flow in patients with Raynaud's disease. In both normal and Raynaud's subjects, selective antagonism of alpha1- or alpha2-adrenergic receptors does not abolish local cold-induced vasoconstriction. Therefore, it is likely that a nonadrenergic mechanism contributes to local cold-induced vasoconstriction.

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44

McGrath, Anne. "Clinical Snapshot: Raynaud's Syndrome." American Journal of Nursing 97, no. 1 (January 1997): 34. http://dx.doi.org/10.2307/3465192.

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45

NELSON, COLIN. "Scleroderma Complicates Raynaud's Emergencies." Skin & Allergy News 36, no. 12 (December 2005): 50. http://dx.doi.org/10.1016/s0037-6337(05)70901-3.

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46

Bedarida, G. V., D. Kim, T. F. Blaschke, B. B. Hoffman, and B. B. Hoffman. "Venodilation in Raynaud's disease." Lancet 342, no. 8885 (December 1993): 1451–54. http://dx.doi.org/10.1016/0140-6736(93)92932-j.

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47

Rudnick, Abraham, Ilan Modai, and Avigdor Zelikovski. "Fluoxetine-induced Raynaud's phenomenon." Biological Psychiatry 41, no. 12 (June 1997): 1218–21. http://dx.doi.org/10.1016/s0006-3223(97)00188-1.

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48

Ortega Vicente, Elena, and Mercedes Garrido Redondo. "Raynaud's Phenomenon in Children." Reumatología Clínica (English Edition) 12, no. 6 (November 2016): 342–44. http://dx.doi.org/10.1016/j.reumae.2015.08.006.

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49

Janini, S. DaN, D. G. I. Scott, J. S. Coppock, P. A. Bacon, and M. J. Kendall. "ENALAPRIL IN RAYNAUD'S PHENOMENON." Journal of Clinical Pharmacy and Therapeutics 13, no. 2 (April 1988): 145–50. http://dx.doi.org/10.1111/j.1365-2710.1988.tb00171.x.

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50

De Sanctis, G., A. Frezzolini, S. Cadoni, R. Perricone, V. Bottari, and L. Fontana. "Raynaud's Phenomenon: Immunological Aspects." International Journal of Immunopathology and Pharmacology 9, no. 2 (September 1996): 33. http://dx.doi.org/10.1177/039463209600900216.

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