Academic literature on the topic 'Rat cholinergic neurones'

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Journal articles on the topic "Rat cholinergic neurones"

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Ekelund, K. M., and E. Ekblad. "Structural, neuronal, and functional adaptive changes in atrophic rat ileum." Gut 45, no. 2 (1999): 236–45. http://dx.doi.org/10.1136/gut.45.2.236.

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BACKGROUNDInactivity of the gut leads to atrophic changes of which little is known.AIMSTo investigate structural, neuronal, and functional changes occurring in bypassed rat ileum.METHODSMorphometry was used to characterise the atrophic changes. The numbers of enteric neurones, their expression of neurotransmitters, and the presence of interstitial cells of Cajal were studied using immunocytochemistry and in situ hybridisation. Motor activity was studied in vitro.RESULTSAdaptive changes in bypassed ileum include atrophy and remodelling of the gut wall. The total numbers of submucous and myenter
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Atterwill, Christopher K. "Brain Reaggregate Cultures in Neurotoxicological Investigations: Studies with Cholinergic Neurotoxins." Alternatives to Laboratory Animals 16, no. 3 (1989): 221–30. http://dx.doi.org/10.1177/026119298901600304.

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The number of neurotoxicants which produce ‘lesions’ in organotypic brain reaggregate cultures in vitro, which correlate with known in vivo actions, is growing. With respect to cholinergic neurones, this includes kainic acid, organophosphorus compounds and, in our hands, ethylcholine mustard aziridinium (ECMA) and aluminium. We have demonstrated that in vitro exposure to low concentrations of ECMA (12.5μM) produces a two-stage lesion in rat whole-brain reaggregate cultures, corresponding to initial direct inhibition of choline acetyltransferase (ChAT), followed by a later loss of cholinergic n
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Kumamoto, Eiichi, and Yuzo Murata. "GABAA-receptor channels on rat cholinergic septal neurones in culture." Neuroscience Research Supplements 19 (January 1994): S51. http://dx.doi.org/10.1016/0921-8696(94)92404-x.

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Atterwill, Christopher K., Wendy J. Davies, and Michael A. Kyriakides. "An Investigation of Aluminium Neurotoxicity using some In Vitro Systems." Alternatives to Laboratory Animals 18, no. 1_part_1 (1990): 181–90. http://dx.doi.org/10.1177/026119299001800119.1.

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It has been shown that acute exposure in vitro to high concentrations of aluminium chloride does not appear to perturb neural function in terms of the electrophysiological properties of lower vertebrate leech neurones. Longer term exposure in vitro, however, both non-specifically inhibits cellular differentiation and also produces neural cytotoxicity in the rat midbrain micromass, mixed cell culture model. Furthermore, previous studies from this laboratory have demonstrated a reduction of cholinergic neuronal function in brain organotypic reaggregate cultures following long-term, but not short
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BINNS, K. E., and T. E. SALT. "The functional influence of nicotinic cholinergic receptors on the visual responses of neurones in the superficial superior colliculus." Visual Neuroscience 17, no. 2 (2000): 283–89. http://dx.doi.org/10.1017/s0952523800172116.

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In the rat, the superficial gray layer (SGS) of the superior colliculus receives glutamatergic projections from the contralateral retina and from the visual cortex. A few fibers from the ipsilateral retina also directly innervate the SGS, but most of the ipsilateral visual input is provided by cholinergic afferents from the opposing parabigeminal nucleus (PBG). Thus, visual input carried by cholinergic afferents may have a functional influence on the responses of SGS neurones. When single neuronal extracellular recording and iontophoretic drug application were employed to examine this possibil
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Yang, Qiner, Anders Hamberger, Nastaran Khatibi, Torgny Stigbrand та Kenneth G. Haglid. "Presence of S-100β in cholinergic neurones of the rat hindbrain". NeuroReport 7, № 18 (1996): 3093–100. http://dx.doi.org/10.1097/00001756-199611250-00060.

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Cross, A. J., and J. F. W. Deakin. "Cortical serotonin receptor subtypes after lesion of ascending cholinergic neurones in rat." Neuroscience Letters 60, no. 3 (1985): 261–65. http://dx.doi.org/10.1016/0304-3940(85)90587-7.

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Pearson, R. C. A., M. V. Sofroniew, and T. P. S. Powell. "Hypertrophy of cholinergic neurones of the rat basal nucleus following section of the corpus callosum." Brain Research 338, no. 2 (1985): 337–40. http://dx.doi.org/10.1016/0006-8993(85)90164-7.

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Vidal, S., B. Raynaud, D. Clarous, and M. J. Weber. "Neurotransmitter plasticity of cultured sympathetic neurones. Are the effects of muscle-conditioned medium reversible?" Development 101, no. 3 (1987): 617–25. http://dx.doi.org/10.1242/dev.101.3.617.

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Muscle-conditioned medium (CM) induces choline acetyltransferase (CAT) activity in primary cultures of new-born rat sympathetic neurones and depresses the development of tyrosine hydroxylase (TOH). By following these two enzymes, we have determined whether (1) the effects of CM are reversible and (2) the neurones progressively lose their sensitivity to CM with time in culture. When neurones were cultured in the presence of 50% CM (CM+ medium), TOH activity developed slowly but CAT activity developed at a high rate. When the cultures were then switched to unconditioned medium (CM- medium), CAT
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Momiyama, Toshihiko. "A patch-clamp analysis of GABAergic synaptic inputs to large cholinergic neurones in the rat striatum." Japanese Journal of Pharmacology 76 (1998): 89. http://dx.doi.org/10.1016/s0021-5198(19)40474-5.

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Dissertations / Theses on the topic "Rat cholinergic neurones"

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Duguid, Gail Louise. "The involvement of the cholinergic and glutamatergic neurotransmitter systems in neuronal processes underlying recognition memory in the rat." Thesis, University of Bristol, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.368392.

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Jourdain, Anne. "Studies on the collateralization of some basal forebrain and mesopontine tegmental projection systems in the rat." Thesis, University of British Columbia, 1988. http://hdl.handle.net/2429/27969.

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Many basal forebrain and mesopontine tegmental cholinergic projection systems tend to overlap in their origins. This raises the possibility that these projection systems are collateralized to innervate divergent areas. In experiment one, the degree to which basal forebrain and mesopontine tegmental neurons that innervate the reticular thalamic nucleus have axons that collateralize to innervate the cortex as well was examined with a retrograde fluorescence labeling method combined with immunohistochemistry. A significant portion of the labeled neurons in the region of the nucleus basalis magnoc
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Reece, Laura J. "Cholinergic effects on developing hippocampal neurons in vitro /." Thesis, Connect to this title online; UW restricted, 1990. http://hdl.handle.net/1773/10558.

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Nair, Sunila. "Effects of 3,4-methylenedioxymethamphetamine (MDMA) on Cholinergic neurons in the rat brain." University of Cincinnati / OhioLINK, 2005. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1123857787.

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Perry, Theresa Fried. "Functional relationship between forebrain cholinergic projections and somatostatin neurons in the rat." Thesis, Virginia Tech, 1990. http://hdl.handle.net/10919/41603.

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The two neuron types that initially degenerate with Alzheimer's Disease are the cholinergic projections from the septum to the hippocampus and from the substantia innominata to the cortex, and the somatostatinergic neurons in the hippocampus and cortex. The functional relationship between these two types of neurons was investigated using folic acid, a neuro-excitant, and cysteamine, a somatostatin depleter. Folic acid causes a neuron to fire at a much higher rate than normal (Spector, 1971). Folic acid was injected into either the septum or the substantia innominata, and the long-term effect
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Carnes, Benjamin J. Carnes. "Compensatory Cortical Sprouting Across the Lifespan of the Rat." Ohio University Honors Tutorial College / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=ouhonors1461167224.

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Dutar, Patrick. "Les systèmes cholinergiques centraux chez le rat adulte et le rat âgé : étude des caractéristiques électrophysiologies et pharmacologiques." Paris 6, 1986. http://www.theses.fr/1986PA066464.

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Etude in vivo chez le rat adulte et âgé à l'aide d'approches multidisciplinaires des caractéristiques des neurons cholinergiques des voies septo-hippocampique et basalo-corticale. Les caractéristiques physiologiques ont été décrites par enregistrements extra et intracellulaires, les propriétés pharmacologiques par applications iontophorétiques, les modifications de ces propriétés ont été étudiées au cours du vieillissement. Enfin une étude anatomique par marquage histologique à la peroxydase a été menée pour définir la voie basalo-corticole.
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Zhang, Zi Wei ZW. "Plasticity of neuroanatomical relationships between cholinergic and dopaminergic axon varicosities and pyramidal cells in the rat medial prefrontal cortex." Thèse, 2011. http://hdl.handle.net/1866/6281.

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Les systèmes cholinergique et dopaminergique jouent un rôle prépondérant dans les fonctions cognitives. Ce rôle est exercé principalement grâce à leur action modulatrice de l’activité des neurones pyramidaux du cortex préfrontal. L’interaction pharmacologique entre ces systèmes est bien documentée mais les études de leurs interactions neuroanatomiques sont rares, étant donné qu’ils sont impliqués dans une transmission diffuse plutôt que synaptique. Ce travail de thèse visait à développer une expertise pour analyser ce type de transmission diffuse en microscopie confocale. Nous avons étudié
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Yu-ting, Wang, and 王昱婷. "Cholinergic Effects on the Neurons of the Rat Suprachiasmatic Nucleus." Thesis, 2005. http://ndltd.ncl.edu.tw/handle/05452627226220672171.

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碩士<br>長庚大學<br>基礎醫學研究所<br>93<br>The suprachiasmatic nucleus (SCN) is the master pacemaker in mammals, with two anatomically and functionally distinct divisions of dorsal (dSCN) and ventral SCN (vSCN). In the SCN, both muscarinc and nictonic cholinergic receptors have been shown to be present and acetylcholine acts directly on SCN neurons. In this study, I used the cell-attached recording technique to investigate the effects of cholinergic agents on the SCN neurons, focusing on the time-dependent responses of both dSCN and vSCN neurons. I found that cholinergic agents altered the spontaneou
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Li, Meng-Jiyuan, and 李孟娟. "Cholinergic Modulation in A7 Noradrenergic Neurons in Rats." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/03942421735677930894.

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碩士<br>臺灣大學<br>動物學研究所<br>98<br>Acetylcholine (ACh) is one of principal neurotransmitters involved in pain modulation. Many behavioral studies have shown that central or peripheral ACh administrations can evoke analgesia, and have proved that cholinergic agonists can serve as a synergistic role of α2 adrenergic receptors-mediated antinociception in the spinal cord. Moreover, recent behavioral researches also indicate that there might be supraspinal interactions between muscarinic cholinergic system and noradrenergic (NAergic) pain descending pathway. Nevertheless, there is currently no direct ev
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Book chapters on the topic "Rat cholinergic neurones"

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Sakamoto, Takashi, Masahiro Kurisaka, and Koreaki Mori. "Changes of Muscarinic Cholinergic Receptors and Cholinergic Neurons in Experimental Acute Hydrocephalic Rat Brains." In Annual Review of Hydrocephalus. Springer Berlin Heidelberg, 1990. http://dx.doi.org/10.1007/978-3-662-11155-0_9.

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Itakura, Toru, Hideyoshi Yokote, Norihiko Komai, and Mamoru Umemoto. "Autotransplantation of Parasympathetic Cholinergic Neurons into Alzheimer Model Rat Brain." In Basic, Clinical, and Therapeutic Aspects of Alzheimer’s and Parkinson’s Diseases. Springer New York, 1990. http://dx.doi.org/10.1007/978-1-4684-5844-2_156.

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Hefti, F., J. Hartikka, and B. Will. "Effects of Nerve Growth Factor on Cholinergic Neurons of the Rat Forebrain." In Brain Plasticity, Learning, and Memory. Springer US, 1985. http://dx.doi.org/10.1007/978-1-4684-5003-3_49.

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Varon, Silvio, Theo Hagg, H. Lee Vahlsing, and Marston Manthorpe. "Nerve Growth Factor in Vivo Actions on Cholinergic Neurons in the Adult Rat CNS." In Cell Function and Disease. Springer US, 1988. http://dx.doi.org/10.1007/978-1-4613-0813-3_21.

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McRae, Amanda, Annelie Wigander, Kerstin Lundmark, et al. "CSF of Patients with Alzheimer’s Disease Contain Antibodies Recognizing Cholinergic Cells in the Rat CNS, and can Protect Cholinergic Neuronal Cultures." In Basic, Clinical, and Therapeutic Aspects of Alzheimer’s and Parkinson’s Diseases. Springer US, 1990. http://dx.doi.org/10.1007/978-1-4684-5847-3_8.

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Arimatsu, Yasuyoshi, and Mami Miyamoto. "Co-Localization of Cholinergic and GABAergic Traits in in Vitro Septohippocampal Neurons from Developing Rats." In Basic, Clinical, and Therapeutic Aspects of Alzheimer’s and Parkinson’s Diseases. Springer New York, 1990. http://dx.doi.org/10.1007/978-1-4684-5844-2_127.

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Hama, Tokiko, Mami Miyamoto, Kaori Noguchi, et al. "Interleukin-6 as a Neurotrophic Factor for Promoting Survival of Septal Cholinergic Neurons and Mesencephalic Catecholaminergic Neurons from Postnatal Rats." In Basic, Clinical, and Therapeutic Aspects of Alzheimer’s and Parkinson’s Diseases. Springer New York, 1990. http://dx.doi.org/10.1007/978-1-4684-5844-2_129.

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Chang, Howard T., and Hui Kuo. "Calcium-Binding Protein (Calbindin D-28k) Immunoreactive Neurons in the Basal Forebrain of the Monkey and the Rat: Relationship with the Cholinergic Neurons." In Advances in Experimental Medicine and Biology. Springer US, 1991. http://dx.doi.org/10.1007/978-1-4757-0145-6_4.

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Hatanaka, Hiroshi, Nobuyuki Takei, and Hiroko Tsukui. "Nerve Growth Factor-Mediated Induction of Choline Acetyltransferase in Fetal and Neonatal Rat Septal Cholinergic Neurons in Organotypic Culture." In Neural Development and Regeneration. Springer Berlin Heidelberg, 1988. http://dx.doi.org/10.1007/978-3-642-73148-8_61.

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Hefti, F., and B. H. Gähwiler. "Cholinergic Neurons of the Rat Forebrain in Slice Cultures; Interactions with Target Tissue and Effects of Nerve Growth Factor." In Neural Development and Regeneration. Springer Berlin Heidelberg, 1988. http://dx.doi.org/10.1007/978-3-642-73148-8_8.

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