Academic literature on the topic 'Rat brain neurochemistry'

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Journal articles on the topic "Rat brain neurochemistry"

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Meredith, Peter A., Morna J. McIntosh, Margaret A. Petty, and John L. Reid. "Effects of lead exposure on rat brain catecholaminergic neurochemistry." Comparative Biochemistry and Physiology Part C: Comparative Pharmacology 89, no. 2 (January 1988): 215–19. http://dx.doi.org/10.1016/0742-8413(88)90213-7.

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Khandelwal, Purnima, Chad E. Beyer, Qian Lin, Lee E. Schechter, and Alvin C. Bach. "Studying Rat Brain Neurochemistry Using Nanoprobe NMR Spectroscopy: a Metabonomics Approach." Analytical Chemistry 76, no. 14 (July 2004): 4123–27. http://dx.doi.org/10.1021/ac049812u.

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Bharatiya, Rahul, Abdeslam Chagraoui, Salomé De Deurwaerdere, Antonio Argiolas, Maria Rosaria Melis, Fabrizio Sanna, and Philippe De Deurwaerdere. "Chronic Administration of Fipronil Heterogeneously Alters the Neurochemistry of Monoaminergic Systems in the Rat Brain." International Journal of Molecular Sciences 21, no. 16 (August 9, 2020): 5711. http://dx.doi.org/10.3390/ijms21165711.

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Fipronil (FPN), a widely used pesticide for agricultural and non-agricultural pest control, is possibly neurotoxic for mammals. Brain monoaminergic systems, involved in virtually all brain functions, have been shown to be sensitive to numerous pesticides. Here, we addressed the hypothesis that chronic exposure to FPN could modify brain monoamine neurochemistry. FPN (10 mg/kg) was chronically administered for 21 days through oral gavage in rats. Thereafter, the tissue concentrations of dopamine (DA) and its metabolites, 3,4-dihydroxyphenylacetic acid (DOPAC) and homovanillic acid; serotonin (5-HT) and its metabolite, 5-hydroxyindoleacetic acid (5-HIAA); and noradrenaline (NA) were measured in 30 distinct brain regions. FPN significantly decreased DA and its metabolite levels in most striatal territories, including the nucleus accumbens and the substantia nigra (SN). FPN also diminished 5-HT levels in some striatal regions and the SN. The indirect index of the turnovers, DOPAC/DA and 5-HIAA/5-HT ratios, was increased in numerous brain regions. FPN reduced the NA content only in the nucleus accumbens core. Using the Bravais–Pearson test to study the neurochemical organization of monoamines through multiple correlative analyses across the brain, we found fewer correlations for NA, DOPAC/DA, and 5-HIAA/5-HT ratios, and an altered pattern of correlations within and between monoamine systems. We therefore conclude that the chronic administration of FPN in rats induces massive and inhomogeneous changes in the DA and 5-HT systems in the brain.
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Pierucci, Massimo, Vincenzo Di Matteo, Arcangelo Benigno, Giuseppe Crescimanno, Ennio Esposito, and Giuseppe Di Giovanni. "The Unilateral Nigral Lesion Induces Dramatic Bilateral Modification on Rat Brain Monoamine Neurochemistry." Annals of the New York Academy of Sciences 1155, no. 1 (February 2009): 316–23. http://dx.doi.org/10.1111/j.1749-6632.2008.03679.x.

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Zahr, Natalie M., Dirk Mayer, Torsten Rohlfing, Oliver Hsu, Shara Vinco, Juan Orduna, Richard Luong, Richard L. Bell, Edith V. Sullivan, and Adolf Pfefferbaum. "Rat strain differences in brain structure and neurochemistry in response to binge alcohol." Psychopharmacology 231, no. 2 (September 13, 2013): 429–45. http://dx.doi.org/10.1007/s00213-013-3253-z.

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Tayebati, Seyed Khosrow, Daniele Tomassoni, and Francesco Amenta. "Spontaneously hypertensive rat as a model of vascular brain disorder: Microanatomy, neurochemistry and behavior." Journal of the Neurological Sciences 322, no. 1-2 (November 2012): 241–49. http://dx.doi.org/10.1016/j.jns.2012.05.047.

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Boczek, Tomasz, Malwina Lisek, Bozena Ferenc, Magdalena Wiktorska, Ivana Ivchevska, and Ludmila Zylinska. "Region-specific effects of repeated ketamine administration on the presynaptic GABAergic neurochemistry in rat brain." Neurochemistry International 91 (December 2015): 13–25. http://dx.doi.org/10.1016/j.neuint.2015.10.005.

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Nielsen, Brian S., Erik H. Larsen, Ole Ladefoged, and Henrik R. Lam. "Subchronic, Low-Level Intraperitoneal Injections of Manganese (IV) Oxide and Manganese (II) Chloride Affect Rat Brain Neurochemistry." International Journal of Toxicology 36, no. 3 (May 2017): 239–51. http://dx.doi.org/10.1177/1091581817704378.

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Manganese (Mn) is neurotoxic and can induce manganism, a Parkinson-like disease categorized as being a serious central nervous system irreversible neurodegenerative disease. An increased risk of developing symptoms of Parkinson disease has been linked to work-related exposure, for example, for workers in agriculture, horticulture, and people living near areas with frequent use of Mn-containing pesticides. In this study, the focus was placed on neurochemical effects of Mn. Rats were dosed intraperitoneally with 0.9% NaCl (control), 1.22 mg Mn (as MnO2)/kg bodyweight (bw)/day, or 2.5 mg Mn (as MnCl2)/kg bw/day for 7 d/wk for 8 or 12 weeks. This dosing regimen adds relevant new knowledge about Mn neurotoxicity as a consequence of low-dose subchronic Mn dosing. Manganese concentrations increased in the striatum, the rest of the brain, and in plasma, and regional brain neurotransmitter concentrations, including noradrenaline, dopamine (DA), 5-hydroxytrytamine, glutamate, taurine, and γ-amino butyric acid, and the activity of acetylcholinesterase changed. Importantly, a target parameter for Parkinson disease and manganism, the striatal DA concentration, was reduced after 12 weeks of dosing with MnCl2. Plasma prolactin concentration was not significantly affected due to a potentially reduced dopaminergic inhibition of the prolactin release from the anterior hypophysis. No effects on the striatal α-synuclein and synaptophysin protein levels were detected.
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O’Leary-Moore, Shonagh K., Andrew P. McMechan, Matthew P. Galloway, and John H. Hannigan. "Neonatal Alcohol-Induced Region-Dependent Changes in Rat Brain Neurochemistry Measured by High-Resolution Magnetic Resonance Spectroscopy." Alcoholism: Clinical and Experimental Research 32, no. 10 (October 2008): 1697–707. http://dx.doi.org/10.1111/j.1530-0277.2008.00747.x.

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Tayebati, Seyed Khosrow, Maria Antonietta Di Tullio, Alberto Ricci, and Francesco Amenta. "Influence of dermal exposure to the pyrethroid insecticide deltamethrin on rat brain microanatomy and cholinergic/dopaminergic neurochemistry." Brain Research 1301 (November 2009): 180–88. http://dx.doi.org/10.1016/j.brainres.2009.09.015.

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Dissertations / Theses on the topic "Rat brain neurochemistry"

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Rooney, Thomas A. "Inositol phospholipid metabolism in rat brain." Thesis, University of Leicester, 1987. http://hdl.handle.net/2381/33609.

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In the studies described in this thesis the ability of muscarinic and ?1-adrenoceptor, as well as depolarising stimuli to initiate phosphoinositide metabolism in various regions of rat brain were examined. Furthermore, the ability of these stimuli to initiate phosphoinositide hydrolysis in developing brain was observed. Both muscarinic and ?1-adrenoceptor-induced phosphoinositide hydrolysis have marked regional distributions in rat brain. This regional distribution of functional responsiveness seems to correlate reasonably well with measurements of known receptor density. It is also clear that there is no variability in the coupling of both of these receptors in rat brain, thus implying a relationship between the functional responses and receptor occupancy. Pirenzepine appears to be able to differentiate between muscarinic receptor-induced phosphoinositide responses in the hindbrain from those in the forebrain regions. Both elevated K+ and veratrine can initiate phosphoinositide hydrolysis in rat brain. The regional responses to elevated K+ seem, at least, in part to be due to transmitter release, although a role for voltage-sensitive Ca++ channels in such responses is indicated by the effects produced by dihydropyridine Ca++ channel antagonists and activators. Muscarinic and ?1-adrenoceptors show different developmental patterns of phosphoinositide responsiveness. The ?1-adrenoceptor seems to be more efficiently coupled during the first two weeks of postnatal development whereas the muscarinic receptor shows no variability in coupling. Instead, carbachol produces supramaximal responses in young rats. Lithium also potentiates [3H]-InsP1 and [3H]-InsP2 accumulations more in young rats. Moreover lithium produces a time-dependent inhibition of [3H]-InsP3 and [3H]-InsP4 in both young and adult rats. Physostigmine produces no enhancement of the response to elevated K+ in young rats. Furthermore, brain slices from young rats seem to be more sensitive to the Ca++ channel activator BAY-K8644. The significance of these results are discussed in the text.
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Thorne, Beverley Ann. "Nicotinic regulation of acetylcholine release from rat brain hippocampus." Thesis, University of Bath, 1990. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.237086.

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Marshall, Fiona. "Cholecystokinin/dopamine interactions in the rat basal ganglia." Thesis, University of Cambridge, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.386170.

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Stephens, P. "Neurochemical studies on the basal forebrain." Thesis, University of Oxford, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.371574.

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Hicks, Gareth A. "Adenosine 5'-triphosphate-sensitive potassium channels in the rat substantia nigra." Thesis, University of Cambridge, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.321402.

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Hidaka, Seiko. "The interneurons and their synaptic organisations in the rat nucleus accumbens." Thesis, University of Oxford, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.365867.

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Evans, Suzanne Marie. "The effects of inhibition of monoamine oxidase activity on the characteristics of 5-hydroxytryptamine release from rat brain synaptosomes." Thesis, Cardiff University, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.375944.

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Sullivan, Aideen Margaret. "The use of organotypic cultures of rat cerebellum for the study of neuromodulatory interactions in the mammalian brain." Thesis, University of Cambridge, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.243197.

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Uys, Joachim De Klerk. "The effects of early life trauma on the neurochemistry and behaviour of the adult rat." Thesis, Link to the online version, 2006. http://hdl.handle.net/10019/1249.

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Theodorsson, Annette. "Estrogen-inducible neuropeptides in the rat brain : role in focal ischemic lesions /." Doctoral thesis, Linköping : Linköpings universitet, 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-4716.

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Books on the topic "Rat brain neurochemistry"

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Cooney, Margaret. Biochemical and morphological analysis of the adult and juvenile rat hippocampal slice preparation. Dublin: University College Dublin, 1996.

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Foster, G. A. Chemical neuroanatomy of the prenatal rat brain: A developmental atlas. Oxford: Oxford University Press, 1998.

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Book chapters on the topic "Rat brain neurochemistry"

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Seidenbecher, Constanze, Karin Richter, and Eckart D. Gundelfinger. "Brevican, a Conditional Proteoglycan from Rat Brain." In Neurochemistry, 901–4. Boston, MA: Springer US, 1997. http://dx.doi.org/10.1007/978-1-4615-5405-9_148.

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Vogel, R., H. Wiesinger, and B. Hamprecht. "Postnatal Development of Malic Enzyme Isoforms in Rat Brain." In Neurochemistry, 765–69. Boston, MA: Springer US, 1997. http://dx.doi.org/10.1007/978-1-4615-5405-9_127.

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Aleksidze, N. G., R. G. Akhalkatsi, and T. Bolotashvili. "Glycoconjugates and Nuclear Membrane Lectin from Rat Brain Cell Nuclei." In Neurochemistry, 909–12. Boston, MA: Springer US, 1997. http://dx.doi.org/10.1007/978-1-4615-5405-9_150.

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Mokrushin, Anatoly A., and Anton Y. Plekhanov. "Analysis of Perfusates Collected from Surviving Rat Brain Olfactory Cortex Slices." In Neurochemistry, 519–21. Boston, MA: Springer US, 1997. http://dx.doi.org/10.1007/978-1-4615-5405-9_87.

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Bashkatova, V., A. Vanin, V. Mikoyan, G. Vitskova, V. Narkevich, and K. Rayevsky. "Nitric Oxide Level Dramatically Increases in the Rat Brain during Epileptiform Seizures." In Neurochemistry, 977–81. Boston, MA: Springer US, 1997. http://dx.doi.org/10.1007/978-1-4615-5405-9_164.

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Francescangeli, Ermelinda, Serena Porcellati, and Gianfrancesco Goracci. "CMP-Dependent Degradation of Platelet-Activating Factor (PAF) by Rat Brain Microsomes." In Neurochemistry, 1029–34. Boston, MA: Springer US, 1997. http://dx.doi.org/10.1007/978-1-4615-5405-9_173.

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Melkonian, M. M., K. G. Karageuzyan, G. A. Hoveyan, A. Sargsian, and L. M. Hovsepian. "Changes in Contents of Phospholipids in Rat Brain Under the Action of Noise." In Neurochemistry, 761–64. Boston, MA: Springer US, 1997. http://dx.doi.org/10.1007/978-1-4615-5405-9_126.

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Ter Horst, Gert J., Jan Gert Nagel, Mike J. L. De Jongste, and Ysbrand D. Van der Werf. "Selective Blood Brain Barrier Dysfunction After Intravenous Injections of RTNFα in the Rat." In Neurochemistry, 141–46. Boston, MA: Springer US, 1997. http://dx.doi.org/10.1007/978-1-4615-5405-9_23.

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Kapuściński, Andrzej. "Catecholamines Levels in the Rat Brain and Plasma during Cardiac Arrest and after Resuscitation." In Neurochemistry, 729–32. Boston, MA: Springer US, 1997. http://dx.doi.org/10.1007/978-1-4615-5405-9_120.

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Rump, S., and I. Jakowicz. "Effects of Repeated Administration of Dizocilpine on 5HT1A Receptor Binding in the Rat Brain." In Neurochemistry, 55–57. Boston, MA: Springer US, 1997. http://dx.doi.org/10.1007/978-1-4615-5405-9_9.

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Conference papers on the topic "Rat brain neurochemistry"

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Sarkisova, Karine, Ekaterina Fedosova, Alla Shatskova, Victor Narkevich, and Vladimir Kudrin. "THE EFFECTS OF MATERNAL METHYL-ENRICHED DIET ON GENETIC ABSENCE EPILEPSY, COMORBID DEPRESSION AND THE BRAIN NEUROCHEMISTRY IN ADULT OFFSPRING OF WAG/RIJ RATS." In XVII INTERNATIONAL INTERDISCIPLINARY CONGRESS NEUROSCIENCE FOR MEDICINE AND PSYCHOLOGY. LCC MAKS Press, 2021. http://dx.doi.org/10.29003/m2311.sudak.ns2021-17/334-335.

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