Journal articles on the topic 'Rasfonin'

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1

Bhuniya, Rajib, and Samik Nanda. "Asymmetric total synthesis of (−)-rasfonin." Tetrahedron 69, no. 3 (January 2013): 1153–65. http://dx.doi.org/10.1016/j.tet.2012.11.051.

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2

Huang, Yange, Adriaan J. Minnaard, and Ben L. Feringa. "A concise asymmetric synthesis of (−)-rasfonin." Org. Biomol. Chem. 10, no. 1 (2012): 29–31. http://dx.doi.org/10.1039/c1ob06700a.

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3

TOMIKAWA, TAIJIRO, KAZUO SHIN-YA, KEIKO FURIHATA, TAISEI KINOSHITA, ATSUSHI MIYAJIMA, HARUO SETO, and YOICHI HAYAKAWA. "Rasfonin, a New Apoptosis Inducer in ras-dependent Cells from Talaromyces sp." Journal of Antibiotics 53, no. 8 (2000): 848–50. http://dx.doi.org/10.7164/antibiotics.53.848.

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4

Boeckman, Robert K., Justin M. Niziol, and Kyle F. Biegasiewicz. "Scalable Synthesis of (−)-Rasfonin Enabled by a Convergent Enantioselective α-Hydroxymethylation Strategy." Organic Letters 20, no. 16 (August 3, 2018): 5062–65. http://dx.doi.org/10.1021/acs.orglett.8b02222.

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5

Yan, Siyuan, Yongsheng Che, and Xuejun Jiang. "Proteasome inhibition attenuates rasfonin-induced autophagy concurring with the upregulation of caspase-dependent apoptosis." Mycology 7, no. 1 (January 2, 2016): 29–35. http://dx.doi.org/10.1080/21501203.2016.1147091.

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6

Wang, Weijun, Hui Sun, Yongsheng Che, and Xuejun Jiang. "Rasfonin promotes autophagy and apoptosis via upregulation of reactive oxygen species (ROS)/JNK pathway." Mycology 7, no. 2 (April 2, 2016): 64–73. http://dx.doi.org/10.1080/21501203.2016.1170073.

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7

Sun, Hui, Weijun Wang, Yongsheng Che, and Xuejun Jiang. "Fungal secondary metabolites rasfonin induces autophagy, apoptosis and necroptosis in renal cancer cell line." Mycology 7, no. 2 (April 2, 2016): 81–87. http://dx.doi.org/10.1080/21501203.2016.1181114.

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8

Tomikawa, Taijiro, Kazuo Shin-Ya, Keiko Furihata, Taisei Kinoshita, Atsushi Miyajima, Haruo Seto, and Yoichi Hayakawa. "ChemInform Abstract: Rasfonin, a New Apoptosis Inducer in ras-Dependent Cells from Talaromyces sp." ChemInform 32, no. 3 (January 16, 2001): no. http://dx.doi.org/10.1002/chin.200103227.

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9

Lu, Q., S. Yan, H. Sun, W. Wang, Y. Li, X. Yang, X. Jiang, Y. Che, and Z. Xi. "Akt inhibition attenuates rasfonin-induced autophagy and apoptosis through the glycolytic pathway in renal cancer cells." Cell Death & Disease 6, no. 12 (December 2015): e2005-e2005. http://dx.doi.org/10.1038/cddis.2015.344.

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10

Akiyama, Kohki, Shunsuke Yamamoto, Haruhiro Fujimoto, and Masami Ishibashi. "Total synthesis of TT-1 (rasfonin), an α-pyrone-containing natural product from a fungus Trichurus terrophilus." Tetrahedron 61, no. 7 (February 2005): 1827–33. http://dx.doi.org/10.1016/j.tet.2004.12.013.

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11

Akiyama, Kohki, Souichi Kawamoto, Haruhiro Fujimoto, and Masami Ishibashi. "Absolute stereochemistry of TT-1 (rasfonin), an α-pyrone-containing natural product from a fungus, Trichurus terrophilus." Tetrahedron Letters 44, no. 46 (November 2003): 8427–31. http://dx.doi.org/10.1016/j.tetlet.2003.09.136.

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12

Xiao, Z., L. Li, Y. Li, W. Zhou, J. Cheng, F. Liu, P. Zheng, Y. Zhang, and Y. Che. "Rasfonin, a novel 2-pyrone derivative, induces ras-mutated Panc-1 pancreatic tumor cell death in nude mice." Cell Death & Disease 5, no. 5 (May 2014): e1241-e1241. http://dx.doi.org/10.1038/cddis.2014.213.

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13

Boeckman,, Robert K., Joseph E. Pero, and Debra J. Boehmler. "Toward the Development of a General Chiral Auxiliary. Enantioselective Alkylation and a New Catalytic Asymmetric Addition of Silyloxyfurans: Application to a Total Synthesis of (−)-Rasfonin." Journal of the American Chemical Society 128, no. 34 (August 2006): 11032–33. http://dx.doi.org/10.1021/ja063532+.

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14

Hou, Bolin, Haiwen Huang, Yueqian Li, Jingnan Liang, Zhijun Xi, Xuejun Jiang, Ling Liu, and Erwei Li. "Grb2 interacts with necrosome components and is involved in rasfonin-induced necroptosis." Cell Death Discovery 8, no. 1 (July 13, 2022). http://dx.doi.org/10.1038/s41420-022-01106-1.

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AbstractThe underlying mechanism by which growth factor receptor-bound protein 2 (Grb2) regulates necroptosis remains unexplored. In the present study, we found that rasfonin, a fungal natural product and an activator of necroptosis, enhanced Grb2 binding to receptor-interacting serine/threonine kinase 1 (RIP1), which plays a critical role in regulating programmed necrosis. Moreover, we observed that SQSTM/p62 (p62), a protein that can form necrosomes with RIP1, increased its interaction with Grb2 upon rasfonin challenge. Although it has been used as an activator of autophagy in our previous study, here we found that a high dose of rasfonin was able to inhibit autophagic process. Inhibition of RIP1 either chemically or genetically reversed the inhibition of rasfonin on autophagy, whereas knockdown of Grb2 markedly reduced rasfonin-induced necrosis. Additionally, we found that the compound failed to upregulate the expression of RIP1 in Grb2-deprived cells. In summary, our data revealed that Grb2 actively participated in rasfonin-induced necroptosis by interacting with the components of necrosome and mediating their expression.
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15

Akiyama, Kohki, Shunsuke Yamamoto, Haruhiro Fujimoto, and Masami Ishibashi. "Total Synthesis of TT-1 (Rasfonin), an α-Pyrone-Containing Natural Product from a Fungus Trichurus terrophilus." ChemInform 36, no. 26 (June 28, 2005). http://dx.doi.org/10.1002/chin.200526148.

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16

Akiyama, Kohki, Souichi Kawamoto, Haruhiro Fujimoto, and Masami Ishibashi. "Absolute Stereochemistry of TT-1 (Rasfonin), an α-Pyrone-Containing Natural Product from a Fungus, Trichurus terrophilus." ChemInform 35, no. 9 (March 2, 2004). http://dx.doi.org/10.1002/chin.200409229.

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17

Hou, Bolin, Shuchun Liu, Erwei Li, and Xuejun Jiang. "Different Role of Raptor and Rictor in Regulating Rasfonin‐Induced Autophagy and Apoptosis in Renal Carcinoma Cells." Chemistry & Biodiversity 17, no. 12 (November 26, 2020). http://dx.doi.org/10.1002/cbdv.202000743.

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18

Boeckman, Robert K. Jr, Joseph E. Pero, and Debra J. Boehmler. "Toward the Development of a General Chiral Auxiliary. Enantioselective Alkylation and a New Catalytic Asymmetric Addition of Silyloxyfurans: Application to a Total Synthesis of (-)-Rasfonin." ChemInform 38, no. 3 (January 16, 2007). http://dx.doi.org/10.1002/chin.200703200.

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