Relevant bibliographies by topics / Randomized controlled trials

Academic literature on the topic 'Randomized controlled trials'

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Published: 4 June 2021
Last updated: 21 February 2023

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Journal articles on the topic "Randomized controlled trials"

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Stolberg, Harald O., Geoffrey Norman, and Isabelle Trop. "Randomized Controlled Trials." American Journal of Roentgenology 183, no. 6 (December 2004): 1539–44. http://dx.doi.org/10.2214/ajr.183.6.01831539.

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McCarthy, Colleen M. "Randomized Controlled Trials." Plastic and Reconstructive Surgery 127, no. 4 (April 2011): 1707–12. http://dx.doi.org/10.1097/prs.0b013e31820da3eb.

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SCHULZ, KENNETH F. "Randomized Controlled Trials." Clinical Obstetrics and Gynecology 41, no. 2 (June 1998): 245–56. http://dx.doi.org/10.1097/00003081-199806000-00005.

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Moss, Heather E., Jing Cao, and Stacy L. Pineles. "Randomized Controlled Trials." Journal of Neuro-Ophthalmology 40, no. 1 (March 2020): 3–7. http://dx.doi.org/10.1097/wno.0000000000000873.

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BANERJEE, SUBE. "Randomized controlled trials." International Review of Psychiatry 10, no. 4 (January 1998): 291–303. http://dx.doi.org/10.1080/09540269874646.

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McLeod, Robin. "Randomized, Controlled Trials." Annals of Surgery 244, no. 5 (November 2006): 684–85. http://dx.doi.org/10.1097/01.sla.0000243593.93571.98.

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Marler, John. "Randomized controlled trials." Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders 5, sup1 (September 2004): 42. http://dx.doi.org/10.1080/17434470410019933.

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Smith, C. J. "Randomized controlled trials." Phlebology: The Journal of Venous Disease 26, no. 2 (March 2011): 84–85. http://dx.doi.org/10.1258/phleb.2010.010j02.

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Moffett, Jennifer A. Klaber. "Randomized controlled trials." Clinical Rehabilitation 5, no. 1 (February 1991): 1–4. http://dx.doi.org/10.1177/026921559100500101.

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JAINER, ASHOK KUMAR, and MOHAN CHAWLA. "Randomized Controlled Trials." American Journal of Psychiatry 160, no. 6 (June 2003): 1189–90. http://dx.doi.org/10.1176/appi.ajp.160.6.1189.

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Dissertations / Theses on the topic "Randomized controlled trials"

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Glen, Peter. "Outcome Reporting in Surgical Randomized Controlled Trials." Thesis, Université d'Ottawa / University of Ottawa, 2016. http://hdl.handle.net/10393/34237.

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Background: In September 2005, scientific journals began requiring trial protocol registration to increase transparency and accountability. Objective: My primary objectives were: develop a database of linked protocols and publications for surgical randomized control trials (RCTs); estimate the proportion published; and determine the proportion exhibiting selective outcome reporting. Methods: A systematic search of the clinicaltrials.gov database was conducted identifying surgical RCTs, completed between 2006 and 2012. Protocols were linked with publications. Primary outcomes were compared. Results: We identified a cohort of 743 surgical RCT protocols. The proportion of registered trials which published their primary results was 0.49 (n=364). The proportion of selective outcome reporting was estimated to be 0.244, significantly lower than the previous estimate (p<0.001). Conclusion: More than half of the completed surgical RCTs were unpublished, and one quarter of those published selectively reported their primary outcome. This supports the notion that significant bias is present in the surgical literature.
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Spieth, Peter Markus, Anne Sophie Kubasch, Ana Isabel Penzlin, Ben Min-Woo Illigens, Kristian Barlinn, and Timo Siepmann. "Randomized controlled trials - a matter of design." Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2017. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-215848.

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Randomized controlled trials (RCTs) are the hallmark of evidence-based medicine and form the basis for translating research data into clinical practice. This review summarizes commonly applied designs and quality indicators of RCTs to provide guidance in interpreting and critically evaluating clinical research data. It further reflects on the principle of equipoise and its practical applicability to clinical science with an emphasis on critical care and neurological research. We performed a review of educational material, review articles, methodological studies, and published clinical trials using the databases MEDLINE, PubMed, and ClinicalTrials.gov. The most relevant recommendations regarding design, conduction, and reporting of RCTs may include the following: 1) clinically relevant end points should be defined a priori, and an unbiased analysis and report of the study results should be warranted, 2) both significant and nonsignificant results should be objectively reported and published, 3) structured study design and performance as indicated in the Consolidated Standards of Reporting Trials statement should be employed as well as registration in a public trial database, 4) potential conflicts of interest and funding sources should be disclaimed in study report or publication, and 5) in the comparison of experimental treatment with standard care, preplanned interim analyses during an ongoing RCT can aid in maintaining clinical equipoise by assessing benefit, harm, or futility, thus allowing decision on continuation or termination of the trial.
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Spieth, Peter Markus, Anne Sophie Kubasch, Ana Isabel Penzlin, Ben Min-Woo Illigens, Kristian Barlinn, and Timo Siepmann. "Randomized controlled trials - a matter of design." Dove Medical Press, 2016. https://tud.qucosa.de/id/qucosa%3A29007.

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Randomized controlled trials (RCTs) are the hallmark of evidence-based medicine and form the basis for translating research data into clinical practice. This review summarizes commonly applied designs and quality indicators of RCTs to provide guidance in interpreting and critically evaluating clinical research data. It further reflects on the principle of equipoise and its practical applicability to clinical science with an emphasis on critical care and neurological research. We performed a review of educational material, review articles, methodological studies, and published clinical trials using the databases MEDLINE, PubMed, and ClinicalTrials.gov. The most relevant recommendations regarding design, conduction, and reporting of RCTs may include the following: 1) clinically relevant end points should be defined a priori, and an unbiased analysis and report of the study results should be warranted, 2) both significant and nonsignificant results should be objectively reported and published, 3) structured study design and performance as indicated in the Consolidated Standards of Reporting Trials statement should be employed as well as registration in a public trial database, 4) potential conflicts of interest and funding sources should be disclaimed in study report or publication, and 5) in the comparison of experimental treatment with standard care, preplanned interim analyses during an ongoing RCT can aid in maintaining clinical equipoise by assessing benefit, harm, or futility, thus allowing decision on continuation or termination of the trial.
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VOLZ, TINA M. "DECISION MAKING REGARDING PARTICIPATION IN RANDOMIZED CONTROLLED TRIALS." University of Cincinnati / OhioLINK, 2007. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1179517141.

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Kashyap, Sonya. "Assisted reproductive medicine: Systematic reviews and randomized controlled trials." Thesis, University of Ottawa (Canada), 2005. http://hdl.handle.net/10393/26940.

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The objective for this thesis was to propose a question in the area of reproductive medicine that could be addressed by a clinical trial. In preparation for such a trial we conducted a systematic review of the topic. Our first question was whether metformin is of benefit compared to clomiphene citrate for ovulation induction and achievement of pregnancy in women with polycystic ovarian syndrome (PCOS). We conducted a systematic review (SR) and meta-analysis of the subject before designing and implementing a randomized controlled trial (RCT). The RCT was terminated for recruitment issues. Our PCOS SR led us to develop a novel ovarian stimulation protocol for poor responders. We used the lessons learned from our failed RCT and another systematic review to design and conduct a feasibility randomized controlled trial on the use of aromatase inhibitors to improve pregnancy outcomes for in-vitro fertilization in poor responders. We successfully completed the pilot study and found a trend towards increased clinical pregnancy rates for patients who received the study versus the standard protocol. The pilot study provides recommendations for the definitive trial.
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Adjei, Seth Akonor. "Refining Prerequisite Skill Structure Graphs Using Randomized Controlled Trials." Digital WPI, 2018. https://digitalcommons.wpi.edu/etd-dissertations/177.

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Prerequisite skill structure graphs represent the relationships between knowledge components. Prerequisite structure graphs also propose the order in which students in a given curriculum need to be taught specific knowledge components in order to assist them build on previous knowledge and improve achievement in those subject domains. The importance of accurate prerequisite skill structure graphs can therefore not be overemphasized. In view of this, many approaches have been employed by domain experts to design and implement these prerequisite structures. A number of data mining techniques have also been proposed to infer these knowledge structures from learner performance data. These methods have achieved varied degrees of success. Moreover, to the best of our knowledge, none of the methods have employed extensive randomized controlled trials to learn about prerequisite skill relationships among skills. In this dissertation, we motivate the need for using randomized controlled trials to refine prerequisite skill structure graphs. Additionally, we present PLACEments, an adaptive testing system that uses a prerequisite skill structure graph to identify gaps in students’ knowledge. Students with identified gaps are assisted with more practice assignments to ensure that the gaps are closed. PLACEments additionally allows for randomized controlled experiments to be performed on the underlying prerequisite skill structure graph for the purpose of refining the structure. We present some of the different experiment categories which are possible in PLACEments and report the results of one of these experiment categories. The ultimate goal is to inform domain experts and curriculum designers as they create policies that govern the sequencing and pacing of contents in learning domains whose content lend themselves to sequencing. By extension students and teachers who apply these policies benefit from the findings of these experiments.
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Yeung, Wing-fai, and 楊穎輝. "Acupuncture for insomnia: a systematic reviewand randomized placebo-controlled trials." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2009. http://hub.hku.hk/bib/B43572157.

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Zhang, Li, Isola Ajiferuke, and Margaret Sampson. "Optimizing search strategies to identify randomized controlled trials in MEDLINE." BioMed Central, 2006. http://hdl.handle.net/10388/41.

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Background The Cochrane Highly Sensitive Search Strategy (HSSS), which contains three phases, is widely used to identify Randomized Controlled Trials (RCTs) in MEDLINE. Lefebvre and Clarke suggest that reviewers might consider using four revisions of the HSSS. The objective of this study is to validate these four revisions: combining the free text terms volunteer, crossover, versus, and the Medical Subject Heading CROSS-OVER STUDIES with the top two phases of the HSSS, respectively. Methods We replicated the subject search for 61 Cochrane reviews. The included studies of each review that were indexed in MEDLINE were pooled together by review and then combined with the subject search and each of the four proposed search strategies, the top two phases of the HSSS, and all three phases of the HSSS. These retrievals were used to calculate the sensitivity and precision of each of the six search strategies for each review. Results Across the 61 reviews, the search term versus combined with the top two phases of the HSSS was able to find 3 more included studies than the top two phases of the HSSS alone, or in combination with any of the other proposed search terms, but at the expense of missing 56 relevant articles that would be found if all three phases of the HSSS were used. The estimated time needed to finish a review is 1086 hours for all three phases of the HSSS, 823 hours for the strategy versus, 818 hours for the first two phases of the HSSS or any of the other three proposed strategies. Conclusion This study shows that compared to the first two phases of the HSSS, adding the term versus to the top two phases of the HSSS balances the sensitivity and precision in the reviews studied here to some extent but the differences are very small. It is well known that missing relevant studies may result in bias in systematic reviews. Reviewers need to weigh the trade-offs when selecting the search strategies for identifying RCTs in MEDLINE.
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Zhao, Siyuan. "Towards Personalized Learning using Counterfactual Inference for Randomized Controlled Trials." Digital WPI, 2018. https://digitalcommons.wpi.edu/etd-dissertations/189.

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Personalized learning considers that the causal effects of a studied learning intervention may differ for the individual student (e.g., maybe girls do better with video hints while boys do better with text hints). To evaluate a learning intervention inside ASSISTments, we run a randomized control trial (RCT) by randomly assigning students into either a control condition or a treatment condition. Making the inference about causal effects of studies interventions is a central problem. Counterfactual inference answers “What if� questions, such as "Would this particular student benefit more if the student were given the video hint instead of the text hint when the student cannot solve a problem?". Counterfactual prediction provides a way to estimate the individual treatment effects and helps us to assign the students to a learning intervention which leads to a better learning. A variant of Michael Jordan's "Residual Transfer Networks" was proposed for the counterfactual inference. The model first uses feed-forward neural networks to learn a balancing representation of students by minimizing the distance between the distributions of the control and the treated populations, and then adopts a residual block to estimate the individual treatment effect. Students in the RCT usually have done a number of problems prior to participating it. Each student has a sequence of actions (performance sequence). We proposed a pipeline to use the performance sequence to improve the performance of counterfactual inference. Since deep learning has achieved a huge amount of success in learning representations from raw logged data, student representations were learned by applying the sequence autoencoder to performance sequences. Then, incorporate these representations into the model for counterfactual inference. Empirical results showed that the representations learned from the sequence autoencoder improved the performance of counterfactual inference.
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Torgerson, Carole. "Systematic reviews of randomized controlled trials in literacy research : methodological challenges." Thesis, University of Sheffield, 2006. http://etheses.whiterose.ac.uk/14638/.

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Introduction: In this item a 'tertiary' review of systematic reviews in literacy learning is presented. It explores the methodological quality of the identified systematic reviews and identifies the primary data that are used for the in-depth methodological work in Item 3 on the two main threats to the validity of systematic reviews: publication bias and design bias. Background: Recent governments in the UK have introduced a number of initiatives aimed at improving the literacy levels of children. It is important, therefore, that policy and practice are informed by the most rigorous available evidence, particularly for questions of effectiveness in literacy learning. It is also important that this evidence is subjected to rigorous critical scrutiny. Methods: Systematic reviews undertaken in the field of literacy learning in English in the years between 1983 and 2003 were searched for, located and quality assessed. The scope of the review was limited to systematic reviews of experimental research evaluating literacy interventions with quantifiable literacy outcome measures in English as a first (not second or additional) language and focusing on children and young people in school settings up to the age of 18. Results: A total of 14 systematic reviews containing meta-analyses and meeting all the inclusion criteria were included in the tertiary review. The following data were extracted from the reviews: literacy interventions, outcomes evaluated and effect sizes. The quality of the reviews was examined using an adaptation of the QUORUM statement. Overall the quality of the meta-analyses included in this tertiary review was good. When examining the effect sizes of randomized controlled trials (RCTs) and controlled trials (CTs) separately there was no clear pattern as to whether the RCTs produced a larger or smaller effect size than the CTs. Discussion: Overall the quality of the meta-analyses included in this tertiary review was good. The QUORUM checklist seemed to perform well for the appraisal of educational meta-analyses. All the reviews clearly stated their research question, and their methods of searching for and selecting included studies. Most studies described their data extraction and used some form of quality assessment of included studies. On the other hand, some reviews did have notable methodological weaknesses. Six of the 14 studies did not make an assessment of publication bias, which is potentially a major threat to the validity of any systematic review. In addition, six studies did not provide evidence for reviewer agreement when synthesising the data. There is, therefore, some room for improvement in the methodological quality of systematic reviews in literacy learning. Conclusions: A number of reviews in this tertiary review are judged to be of sufficiently high quality to provide reliable evidence for the effectiveness of literacy interventions.
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Books on the topic "Randomized controlled trials"

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Jadad, Alejandro R., and Murray W. Enkin, eds. Randomized Controlled Trials. Oxford, UK: Blackwell Publishing Ltd, 2007. http://dx.doi.org/10.1002/9780470691922.

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Introduction to randomized controlled clinical trials. 2nd ed. Boca Raton, FL: Chapman & Hall/CRC, 2006.

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Jadad, Alejandro R. Randomized controlled trials: Questions, answers, and musings. 2nd ed. Malden, Mass: Blackwell Pub., 2007.

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Matthews, J. N. S. An introduction to randomized controlled clinical trials. London: Arnold, 2000.

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Twisk, Jos W. R. Analysis of Data from Randomized Controlled Trials. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-81865-4.

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Lelia, Duley, and Farrell Barbara 1946-, eds. Clinical trials. London: BMJ Books, 2002.

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Kim, KyungMann, Frank Bretz, Ying Kuen K. Cheung, and Lisa V. Hampson. Handbook of Statistical Methods for Randomized Controlled Trials. Boca Raton: Chapman and Hall/CRC, 2021. http://dx.doi.org/10.1201/9781315119694.

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Brink, Wim van den. Medical co-prescription of heroin: Two randomized controlled trials. Utrecht: Central Committee on the Treatment of Heroin Addicts, 2002.

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Randomized clinical trials of nonpharmacologic treatments. Boca Raton: Chapman and Hall/CRC, 2012.

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J, Domanski Michael, and McKinlay Sonja, eds. Successful randomized trials: A handbook for the 21st century. Philadelphia: Lippincott Williams & Wilkins, 2009.

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Book chapters on the topic "Randomized controlled trials"

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Jørgensen, Carsten René. "Randomized Controlled Trials." In The Psychotherapeutic Stance, 53–70. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-20437-2_5.

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Floresco, Stan, Robert Kessler, Ronald L. Cowan, Robert Kessler, Ronald L. Cowan, Mark Slifstein, Andrea Cipriani, et al. "Randomized Controlled Trials." In Encyclopedia of Psychopharmacology, 1112–19. Berlin, Heidelberg: Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-540-68706-1_375.

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Kalva, Nikhil R., and James F. Graumlich. "Randomized Controlled Trials." In Applying Comparative Effectiveness Data to Medical Decision Making, 13–25. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-23329-1_2.

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Cipriani, Andrea, and John Geddes. "Randomized Controlled Trials." In Encyclopedia of Psychopharmacology, 1420–28. Berlin, Heidelberg: Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-642-36172-2_375.

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Moayyedi, Paul, and Richard H. Hunt. "Randomized Controlled Trials." In GI Epidemiology, 113–18. Chichester, UK: John Wiley & Sons, Ltd, 2014. http://dx.doi.org/10.1002/9781118727072.ch12.

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Torgerson, Carole J., David J. Torgerson, and Celia A. Taylor. "Randomized Controlled Trials." In Handbook of Practical Program Evaluation, 158–76. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2015. http://dx.doi.org/10.1002/9781119171386.ch7.

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Armour, Mike, Carolyn Ee, and Genevieve Z. Steiner. "Randomized Controlled Trials." In Handbook of Research Methods in Health Social Sciences, 645–62. Singapore: Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-10-5251-4_94.

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Ray, Dee C. "Randomized Controlled Trials." In Making Research Relevant, 125–40. New York, NY : Routledge, 2018.: Routledge, 2018. http://dx.doi.org/10.4324/9781315179353-9.

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Armour, Mike, Carolyn Ee, and Genevieve Z. Steiner. "Randomized Controlled Trials." In Handbook of Research Methods in Health Social Sciences, 1–18. Singapore: Springer Singapore, 2018. http://dx.doi.org/10.1007/978-981-10-2779-6_94-1.

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Cipriani, Andrea, and John Geddes. "Randomized Controlled Trials." In Encyclopedia of Psychopharmacology, 1–10. Berlin, Heidelberg: Springer Berlin Heidelberg, 2014. http://dx.doi.org/10.1007/978-3-642-27772-6_375-2.

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Conference papers on the topic "Randomized controlled trials"

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Movahedi, Mahnush, Benjamin M. Case, James Honaker, Andrew Knox, Li Li, Yiming Paul Li, Sanjay Saravanan, Shubho Sengupta, and Erik Taubeneck. "Privacy-Preserving Randomized Controlled Trials." In CCS '21: 2021 ACM SIGSAC Conference on Computer and Communications Security. New York, NY, USA: ACM, 2021. http://dx.doi.org/10.1145/3474123.3486764.

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Mayer, Tobias, Elena Cabrio, and Serena Villata. "Evidence Type Classification in Randomized Controlled Trials." In Proceedings of the 5th Workshop on Argument Mining. Stroudsburg, PA, USA: Association for Computational Linguistics, 2018. http://dx.doi.org/10.18653/v1/w18-5204.

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Mathioudakis, Alexander, Markus Fally, Rebecca Robey, Thomas Willams, Faiuna Haseeb, Ahmed Kouta, Paul Dark, Andrew Bentley, Jørgen Vestbo, and Tim Felton. "Outcomes reported in pneumonia randomized controlled trials." In ERS International Congress 2021 abstracts. European Respiratory Society, 2021. http://dx.doi.org/10.1183/13993003.congress-2021.pa1754.

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Shieh, Alexander Te-Wei, Yung-Sung Chuang, Shang-Yu Su, and Yun-Nung Chen. "Towards Understanding of Medical Randomized Controlled Trials by Conclusion Generation." In Proceedings of the Tenth International Workshop on Health Text Mining and Information Analysis (LOUHI 2019). Stroudsburg, PA, USA: Association for Computational Linguistics, 2019. http://dx.doi.org/10.18653/v1/d19-6214.

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Khan, Nadia, Travis J. Matics, Priti Jani, and Jason M. Kane. "The Fragility Index in Pediatric Critical Care Randomized Controlled Clinical Trials." In Selection of Abstracts From NCE 2016. American Academy of Pediatrics, 2018. http://dx.doi.org/10.1542/peds.141.1_meetingabstract.319.

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Verstraete, Kenneth, Nilakash Das, Iwein Gyselinck, Maarten De Vos, and Wim Janssens. "Machine learning for estimating individual treatment effects in randomized controlled trials." In ERS International Congress 2021 abstracts. European Respiratory Society, 2021. http://dx.doi.org/10.1183/13993003.congress-2021.pa3450.

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Requião, Letícia Escorse, Giulia Freitas, Mayanna Macedo, Hanny Gondim, Blenda Antunes, and Bruno Lopes. "Monoclonal antibodies: a new trend for the treatment of Alzheimer’s disease?" In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.439.

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Introduction: Alzheimer’s disease (AD) is the main form of senile dementia. Most of the supposedly disease-modifying treatments in development are directed against the β-amyloid peptide, the administration of exogenous anti-Aβ monoclonal antibodies is a passive immunization strategy aimed at resolving the aggregation of this substance. Objective: Analyze the effectiveness of monoclonal antibodies in the treatment of Alzheimer’s disease. Methods: This is a literature review, based on randomized clinical trials published between 2014 and 2021. The search was conducted in the PubMed database. Results: According to the eligibility criteria, 10 articles were selected. Two of the randomized, double-blind, placebo-controlled phase III studies, one published in 2018 and the other published in 2016, evaluated the intervention with Solanezumab and Bapineuzumab, respectively. Both were not shown to be statistically significant (P = 0.10) for the outcome improvement of the score in the cognitive subscale of 14 and 11 items “Alzheimer’s Disease Assessment Scale” (ADAS-cog14 / 11). However, in a phase II randomized placebo-controlled clinical trial, published in 2021, the use of Donanemab in patients with early Alzheimer’s disease resulted in statistically significant cognitive and functional improvement (P = 0.04) for the outcome change in the scale “Integrated Alzheimer’s Disease Rating” (iADR). Conclusion: Although the use of Donanemab has resulted in cognitive and functional improvement, randomized, double-blind, placebo-controlled, phase III clinical trials need to be conducted to prove the efficacy and safety of its use in clinical practice. Other monoclonal antibodies evaluated did not demonstrate evidence of benefit.
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Ten, K., I. Germund, M. Haustein, M. Khalil, P. Koopman, C. Apitz, L. Duijnhouwer, et al. "Use of Clinical, Surrogate, and Intermediate End Points in Randomized Controlled Fontan Trials." In 51st Annual Meeting German Society for Pediatric Cardiology. Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-1679037.

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Tri Darmayanti, Aquartuti, Tri Nugraha Susilawati, and Bhisma Murti. "A META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS IN THE TREATMENT OF BACTERIAL VAGINOSIS." In Mid International Conference on Public Health 2018. Masters Programme in Public Health, Universitas Sebelas Maret, 2018. http://dx.doi.org/10.26911/mid.icph.2018.05.01.

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Pahus, Laurie, Pierre-Régis Burgel, Jean-Louis Paillasseur, Nicolas Roche, and Pascal Chanez. "Applicability of randomized controlled trials (RCTs) results to real-life patients in COPD." In ERS International Congress 2017 abstracts. European Respiratory Society, 2017. http://dx.doi.org/10.1183/1393003.congress-2017.pa3245.

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Reports on the topic "Randomized controlled trials"

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Deaton, Angus, and Nancy Cartwright. Understanding and Misunderstanding Randomized Controlled Trials. Cambridge, MA: National Bureau of Economic Research, September 2016. http://dx.doi.org/10.3386/w22595.

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Chassang, Sylvain, and Samuel Kapon. Designing Randomized Controlled Trials with External Validity in Mind. Cambridge, MA: National Bureau of Economic Research, December 2022. http://dx.doi.org/10.3386/w30762.

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Chassang, Sylvain, Gerard Padro Miquel, and Erik Snowberg. Selective Trials: A Principal-Agent Approach to Randomized Controlled Experiments. Cambridge, MA: National Bureau of Economic Research, September 2010. http://dx.doi.org/10.3386/w16343.

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Dai, Ning, Fangfang Zhao, Min Fang, Lingyao Kong, Fenglan Pu, and Jianping Liu. Gynostemma Pentaphyllum for Dyslipidemia: A protocol of Systematic Review of Randomized Controlled Trials. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, January 2022. http://dx.doi.org/10.37766/inplasy2022.1.0135.

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Review question / Objective: The aim of this systematic review is to compare Chinese herb Gynostemma pentaphyllum with no treatment, placebo, lipid-lowering agents, or other Chinese herbal products that containing red yeast rice extracts to evaluate effectiveness, safety and cost-effectiveness in people with dyslipidemia to inform clinical practice. To this end, the proposed systematic review will address the following question: Is Chinese herb Gynostemma pentaphyllum effective for dyslipidemia? Information sources: The PubMed, the Cochrane Library, EMBASE, Web of Science, China National Knowledge Infrastructure (CNKI), Chinese Scientific Journal Database (VIP), SinoMed, and Wanfang Data will be searched in January 2022. We also explored the World Health Organization International Clinical Trials Registry Platform (https://www.who.int/clinical-trials-registry-platform), ClinicalTrials.gov (www.clinicaltrials.gov/), and the Chinese Clinical Trial Registry (http://www.chictr.org.cn/index.aspx) for ongoing or unpublished trials to January 2022. Subject words or text words are determined based on published systematic reviews, clinical practice guidelines, ICD-10, ICD-11, MeSH terms, and Emtree. In addition, the reference lists of all identified studies will also be searched to find any relevant trials for inclusion.
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Villa, Michele, Massimo Le Pera, and Michela Bottega. Quality of Abstracts in Randomized Controlled Trials Published in Leading Critical Care Nursing Journals. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, June 2022. http://dx.doi.org/10.37766/inplasy2022.6.0039.

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Review question / Objective: This review aims to evaluate the methodological quality of RCT-abstracts in leading critical care nursing journals. A methodological quality review with the Consolidated Standards of Reporting Trials (CONSORT) criteria will be performed in RCT-abstracts published between 2011-2021 in the first Scopus-ranking (2021) nursing journals. Eligibility criteria: Abstracts of scientific articles will be included if they fulfil the following inclusion criteria: 1) they report the results of parallel and/or cross-over group RCTs, 2) they are written in English, 3) they refer to the care of adult patients with acute/critical illness or conducted in adult ICUs.Manuscripts reporting results of pilot or feasibility studies, cluster trials, observational or cohort studies, interim analyses, economic analyses of RCTs, post-trial follow-up studies, subgroup and secondary analyses of previously published RCTs, editorials and RCTs without an abstract such as RCTs published as letters to the editor, single-subject clinical trials will be excluded.
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Fei, Yutong, Huijuan Cao, Ruyu Xia, Mingkun Yu, Changhao Liang, Yuting Feng, Yiran Du, et al. Methodological challenges when conducting randomized controlled trials in acupuncture: A systematic survey. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, December 2020. http://dx.doi.org/10.37766/inplasy2020.12.0080.

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Gan, Xinling. Sonothrombolysis for acute ischemic stroke: a meta-analysis of randomized controlled trials. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, June 2021. http://dx.doi.org/10.37766/inplasy2021.6.0019.

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Zhong, Yi, Jiahe Wang, Hang Li, Siyuan Yang, Xiang Li, Xinmin Zhou, and Gang Chen. Efficacy and Safety of Eptinezumab for migraine: Findings from randomized controlled trials. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, October 2021. http://dx.doi.org/10.37766/inplasy2021.10.0037.

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Gattrell, William, Paul Farrow, Elizabeth Costigan, Catherine Sheard, Richard White, and Christopher Winchester. Professional medical writing support increases the impact of articles reporting randomized controlled trials. Oxford PharmaGenesis Ltd, April 2016. http://dx.doi.org/10.21305/ismpp2016.001.

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Gattrell, William, Paul Farrow, Elizabeth Costigan, Catherine Sheard, Richard White, and Christopher Winchester. Professional medical writing support increases the impact of articles reporting randomized controlled trials. Oxford PharmaGenesis Ltd, April 2016. http://dx.doi.org/10.21305/ismpp2016.002.

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