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Mukminatien, Nur, Rahmati Putri Yaniafari, Taufik Kurniawan, and Agung Wiradimadja. "CLIL Audio Materials: A Speaking Model for Library Science Department Students." International Journal of Emerging Technologies in Learning (iJET) 15, no. 07 (April 8, 2020): 29. http://dx.doi.org/10.3991/ijet.v15i07.13223.
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To respond to the need of suitable materials for students of Library Science Department of Universitas Negeri Malang, this R&D project was designed to produce audio speaking materials using CLIL approach for blended learning. The method of development covered three main stages: exploring (identification and exploration of needs), developing (pedagogical realization of the product), and validating using peer review, practitioners’ validation, media expert validation, and try out. Three innovations were produced in this study: (1) Competence- CLIL-Based Speaking Syllabus completed with a speaking assessment instrument covering a speaking prompt and a scoring rubric, (2) audio materials accessible through Edmodo, (3) and a module for Speaking activities. The results show that the materials are suitable for the students’ communicative needs, interesting and meaningful for them. They also make learners motivated to learn
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Wan Md Adnan, Wan Nazirah, Nofri Yenita Dahlan, and Ismail Musirin. "Modeling Baseline Energy Using Artificial Neural Network – A Small Dataset Approach." Indonesian Journal of Electrical Engineering and Computer Science 12, no. 2 (November 1, 2018): 662. http://dx.doi.org/10.11591/ijeecs.v12.i2.pp662-669.
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In this work, baseline energy model development using Artificial Neural Network (ANN) with resampling techniques; Cross Validation (CV) and Bootstrap (BS) are presented. Resampling techniques are used to examine the ability of the ANN model to deal with a small dataset. Working days, class days and Cooling Degree Days (CDD) are used as ANN input meanwhile the ANN output is monthly electricity consumption. The coefficient of correlation (R) is used as performance function to evaluate the model accuracy. For this analysis, R is calculated for the entire data set (R_all) and separately for training set (R_train), validation set (R_valid) dan testing set (R_test). The closer R to 1, the higher similarities between targeted and predicted output. The total of two different models with several number of neurons are developed and compared. It can be concluded that all models are capable to train the network. Artificial Neural Network with Bootstrap Cross Validation technique (ANN-BSCV) outperforms Artificial Neural Network with Cross Validation technique (ANN-CV). The 3-6-1 ANN-BSCV, with R_train = 0.95668, R_valid = 0.97553, R_test = 0.85726 and R_all = 0.94079 is selected as the baseline energy model to predict energy consumption for Option C IPMVP.
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Wardani, Riza Ayu, Zulhelmi Zulhelmi2),, and M. Rahmad. "PHYSICS LEARNING DEVELOPMENT WITH APPLYING OUTDOOR INQUIRY APPROACH TO GROW STUDENT SCIENTIFIC WORK HABITS ON GRADE XI SENIOR HIGH SCHOOL." Jurnal Geliga Sains: Jurnal Pendidikan Fisika 6, no. 1 (August 13, 2018): 47. http://dx.doi.org/10.31258/jgs.6.1.47-52.
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The purpose of this research to produce learning devices by applying an outdoor-inquiry approach tofostering scientific work habits on the rotational dynamic material and the equilibrium of a valid rigid objects. The benefits of this research are the product can be used as teaching materials teacher guides, add science insight , guide students in self-development and foster the habits of student scientific work. Tthe method research was a Research and Development (R & D). Method steps include potentials and problems, literature studies and information gathering, product design, validation, and proven design. Data collection was done through learning device validation sheet by 5 validators, consisting of 3 physics education lecturers and 2 physics teachers. The instrument of learning device validity developed consisted of RPP validation instrument, LKPD and understanding items. Validation is done by two stages, that is validation phase I and validation phase II. The result of learning device validation phase I get the average value 2,78 with high category. The result of learning device validation phase II obtained the average value 3,15 with high category.
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Gorumutchu, Giri Prasad, and Venkata Nadh Ratnakaram. "Oxidative Coupling: A Tranquil Approach for Determination of Selexipag by Visible Spectrophotometry." Oriental Journal of Chemistry 34, no. 6 (November 13, 2018): 3112–17. http://dx.doi.org/10.13005/ojc/340656.
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The present study is a first report on development of a spectrophotometric method for determination of selexipag (used to cure pulmonary arterial hypertension) in bulk and tablet formulation and its validation. The basis of the proposed method is formation of a chromophore (of λ max 600 nm) in presence of acidic ferric chloride by oxidative coupling reaction between selexipag and MBTH (3-methylbenzo-thiazolin-2-one hydrazone) solution. Regression analysis (r > 0.999) shows that the plotted calibration curve exhibits good linearity in the studied range of concentration (5 – 30 μg mL-1). As per the existing guidelines of ICH, various parameters of the method were tested for validation. Low values of R.S.D. (< 2 %) were observed indicating that the proposed method is reproducible, accurate and precise.
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Fitria, Endah, Buyung Buyung, and Aisyah Aisyah. "PENGEMBANGAN LEMBAR KERJA SISWA (LKS) BERBASIS CONTEXTUAL TEACHING AND LEARNING (CTL) MATERI SISTEM PERSAMAAN LINEAR TIGA VARIABEL SISWA KELAS X MIA SMAN 9 KOTA JAMBI." PHI: Jurnal Pendidikan Matematika 2, no. 1 (June 1, 2018): 7. http://dx.doi.org/10.33087/phi.v2i1.21.
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Abstract: This research is motivated by the existence of problems in the preparation of LKS being used in SMA Negeri 9 Kota Jambi. LKS is a teaching material that also plays an important role in improving the quality of learning. Preparation of the appropriate LKS and in accordance with the curriculum used is expected to achieve the learning objectives, so it needs continuous LKS development activities. The purpose of this research is to develop LKS based on Contextual Teaching and Learning (CTL) on linear equation system material three valid, practical and effective variables.This type of research development is Research and Development (R & D) with the ADDIE development model. Stages of the ADDIE development model consist of analysis, Design, Development, Implementation, Evaluation. The research instrument consists of Questionnaire and question instrument. Questionnaires consist of validation sheet by the material expert, validation assessment sheet by design expert, validation assessment sheet by media expert, individualized trial evaluation sheet, small group trial evaluation sheet, and evaluation field test sheet. while the question instrument consists of a pre-test and post-test questions. LKS developed, then validated by the validator. Validation results obtained LKS with revisions based on suggestions and comments validator. Validity is illustrated by the percentage of material expert, designer and media experts in 82,61% in "highly valid" category, 76,16% in "valid" category, 90% in "very valid" category. LKS was then piloted into three stages: individual trials with 3 medium and low-skilled students, small group trials with 6 students, and field trials conducted in the real classroom of class X MIA 2 with 34 students. Judging from the comparison of pre-test and post-test values obtained tcount of 15.37 and ttable of 2.03 then tcount > ttable stated there are significant differences. Based on the results of validation, test and test results of learning then obtained the results of research that shows the feasibility of LKS with CTL approach pertained in categories valid, practical and effective.Keywords: Student Worksheet, Contextual Teaching and Learning, the development model of ADDIE
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Stauder, Adrienne, Michael Witthöft, and Ferenc Köteles. "Validation of the Hungarian PHQ-15. A latent variable approach." Ideggyógyászati szemle 74, no. 5-6 (2021): 183–90. http://dx.doi.org/10.18071/isz.74.0183.
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Somatic symptoms without a clear-cut organic or biomedical background, also called “medically unexplained” or “somatoform” symptoms, are frequent in primary and secondary health care. They are often accompanied by depression and/or anxiety, and cause functional impairment. The Patient Health Questionnaire Somatic Symptom Scale (PHQ-15) was developed to measure somatic symptom distress based on the frequency and bothersomeness of non-specific somatic symptoms. The study aimed to (1) evaluate the Hungarian version of the PHQ-15 from a psychometric point of view; (2) replicate the bifactor structure and associations with negative affect described in the literature; and (3) provide the Hungarian clinical and scientific community with reference (normal) values split by sex and age groups. PHQ-15, depression (BDI-R), and subjective well-being (WHO-5) scores obtained from a large (n = 5020) and close to representative community sample (Hungarostudy 2006) were subjected to correlation analysis and linear structural equation modeling. The PHQ-15 showed good internal consistency (Cronbach’s α = 0.810; McDonald’s ω = 0.819) and moderate to strong correlation with the BDI-R (rs = .49, p < 0.001) and WHO-5 (rs = -.48, p < 0.001). Fit of the bifactor structure was excellent; in independent analyses, the general factor was strongly associated with depression (β = 0.656±0.017, p < 0.001) and well-being (β = -0.575±0.015, p < 0.001), whereas the symptom specific factors were only weakly or not related to these constructs. The PHQ-15 score was higher in females and showed a weak positive association with age. The Hungarian PHQ-15 is a psychometrically sound scale which is positively associated with depression and negatively related to subjective well-being. The bifactor structure indicates the existence and meaningfulness of a general factor representing the affective-motivational component of somatic symptom distress. The Hungarian version of the PHQ-15 is a brief and usable tool for the pre-screening of somatization disorder (DSM-IV) or somatic symptom disorder (DSM-5). The reported reference values can be used in the future for both clinical and research purposes.
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Rudakova, Olha, Svitlana Gubar, Nataliia Smielova, Maksym Yaremenko, Nataliia Bevz, and Victoriya Georgiyants. "Development of a unified approach to the method of identification, quantitative determination of active substances and accompanying impurities in a combined drug by HPLC method." ScienceRise: Pharmaceutical Science, no. 2(36) (April 29, 2022): 81–89. http://dx.doi.org/10.15587/2519-4852.2022.255851.
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The aim of the work is to develop a method of identification, quantification of acetylsalicylic and ascorbic acids in the combined presence and concomitant impurities in the combined drug in the form of effervescent powder for preparation of oral solution by liquid chromatography and study of validation characteristics. Materials and methods. ProStar liquid chromatograph with “Varian” spectrophotometric detector. Chromatographic column with a size of 150×4.6 mm, filled with aminopropylsilyl silica gel for chromatography (Supelcosil LC-NH2, “Supelco”) with a precolumn (particle size 3 μm), mobile phase - buffer solution pH 3.2 - acetonitrile P (80:20), elution mode – isocratic; mobile phase velocity – 1.2 ml/min; the detection wavelength is 240 nm. Results. To determine acetylsalicylic and ascorbic acids by high-performance liquid chromatography with UV detection, the optimal chromatographic conditions were selected considering the influence of other active and excipients in the drug. To prove the possibility of applying the proposed technique in the subsequent analysis of the effervescent powder, its validation was performed. The obtained validation characteristics indicate that the method of quantitative determination of acetylsalicylic acid in the studied dosage form corresponds to the parameters: accuracy, precision, linearity ( =0.92≤max =1.60, d=0.19≤maxd=0.51, a=0.17 max a=2.60, r=0.9994 min r=0.9981). In the quantitative determination of ascorbic acid in the combined effervescent powder it is established that the correctness, precision, linearity are performed ( =0.86≤max =1.60, d=0.02≤max d=0.51, a=1.99 max a=2.60, r=0.9997 min r=0.9981). Conclusions. A new method for the identification, quantification of acetylsalicylic and ascorbic acids in the combined presence and concomitant impurities in the effervescent powder using high performance liquid chromatography has been developed. The validation of the proposed method is carried out and its acceptability for use in pharmaceutical analysis is proved
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Ilmiyah, Azni Maziyatul, Aulia Sthephani, Rezi Ariawan, Agus Dahlia, and Riska Novia Sari. "Pengembangan perangkat pembelajaran matematika dengan pendekatan CTL materi segi empat kelas VII MTs Negeri 3 Siak." Journal of Didactic Mathematics 2, no. 3 (December 27, 2021): 101–10. http://dx.doi.org/10.34007/jdm.v2i3.959.
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The purpose of this research to describe the level validity of mathematics lesson plan by using the Contextual Teaching and Learning (CTL) Approach on Quadrangle Substance at Grade VII MTs Negeri 3 Siak which was valid test. The development model in this research used an R&D model with six stages were the researcher have modified depends on the needs and conditions with current situation now it’s covid-19 pandemic. These six stages arepotential and problems, data collection, product design, design validation, design revision and final product. The data collection technique used in this research was the validation of lesson plan, the kind of data collection instrument was the form of a validation sheet. While the data analysis technique used in the form of descriptive analysis by describing the validity of the lesson plan which was developed by the researcher. The results of this research, the RPP validation were 85.86% with very valid criteria. While the results of LKPD validation were 89.81% with very valid criteria. Based on the results of this research, it can be concluded that the development of mathematics lesson plan with a Contextual Teaching and Learning (CTL) approach on quadrangle substance at grade VII MTs Negeri 3 Siak has been suitable for the validity.
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Melinda, Nur Oktavia, and Rezi Ariawan. "Pengembangan Perangkat Pembelajaran Matematika dengan Pendekatan Realistic Mathematics Education (RME) pada Materi Prisma Dan Limas Kelas VIII SMP." Jurnal Absis: Jurnal Pendidikan Matematika dan Matematika 4, no. 1 (October 30, 2021): 380–91. http://dx.doi.org/10.30606/absis.v4i1.837.
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This study aims to produce mathematics learning tools in the form of Lesson Plans (RPP) and Student Worksheets (LKPD) with Realistic Mathematics Education (RME) Approaches in Junior High Schools that have been tested valid. This study uses the development or R&D method using the ADDIE model, namely: 1) Analysis, 2) Design, 3) Development, 4) Implementation, and 5) Evaluation. The data collection technique used is validation data from experts. The data analysis technique is validation data analysis. From the study results, the results of the RPP validation were 86.77% in the very valid category, and the LKPD validation results were 85.41% in the very valid category. This study obtained that the mathematics learning tools with the Realistic Mathematics Education (RME) Approach in Junior High Schools were very valid.
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Rahmawati, Lia Hariski, and Siti Sri Wulandari. "Pengembangan Lembar Kegiatan Peserta Didik (LKPD) Berbasis Scientific Approach Pada Mata Pelajaran Administrasi Umum Semester Genap Kelas X OTKP di SMK Negeri 1 Jombang." Jurnal Pendidikan Administrasi Perkantoran (JPAP) 8, no. 3 (July 17, 2020): 504–15. http://dx.doi.org/10.26740/jpap.v8n3.p504-515.
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This research development od student activity sheets aims to(1) describe the results of developing students scientific approach based sheets on general administration subjects, (2) describe the feasibility of developed students scientific approach on the subject, (3) describe the learner response to the application development studensts scientific approach that has been developed on the subjects. In general Administration subjects for class X OTKP 1 students at SMK N 1 Jombang. This research is a development uses R&D (the research and development) research with 4-D model consisting of 4 stages, namely defining, designing, development and distributing. this research was conducted at 20 learners in class X OTKP 1 at in SMK Negeri 1 Jombang, the results of the validation of the LKPDoverall score of 86%. The validation from material expersts score is 85%. The validation score of the linguist is 80 % and the validation of the graphic expert is 94% with very strong interpretation. So it can be conluded that the development students research scientific approach based sheets on general Administration subject even semester at SMK Negeri 1 Jombang is declared fit to be used as teaching materials.
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Yeak, Zu-Wei, Khun-Aik Chuah, Choon-Heen Tan, Menagah Ezhumalai, Karuthan Chinna, Kalyana Sundram, and Tilakavati Karupaiah. "Providing Comprehensive Dietary Fatty Acid Profiling from Saturates to Polyunsaturates with the Malaysia Lipid Study-Food Frequency Questionnaire: Validation Using the Triads Approach." Nutrients 13, no. 1 (December 31, 2020): 120. http://dx.doi.org/10.3390/nu13010120.
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To address limited food frequency questionnaire (FFQ) capacity in public health monitoring in Malaysia, we aimed to develop a semi-quantitative FFQ for an adult multiethnic population for comprehensive fatty acid (FA) profiling inclusive of saturated (SFA), monounsaturated (MUFA), polyunsaturated fatty acids (PUFA), PUFA:SFA ratio, trans fatty acids, omega-3 and omega-6 FAs. A 240-food itemed FFQ used diet records (DR) of Malaysia Lipid Study (MLS) participants and fatty acid composition database from laboratory analyzed foods. The developed MLS-FFQ underwent face and content validation before relative validation in a free-living population (n = 114). Validation was facilitated for macronutrient data comparisons between DR and FFQ via Spearman’s correlation coefficient analyses; and for fatty acid composition data by independent pairing of DR, FFQ and plasma triglyceride using the triads method. Moderate correlation between dietary methods was obtained for macronutrients and FAs (r = 0.225–0.457, p < 0.05) except for ω-3 FAs, presenting good agreement with grossly misclassified nutrients <10%. For fatty acid composition data, the magnitude of validity coefficients (z) for SFA, PUFA, PUFA:SFA ratios and ω-6 FAs by all 3 methods were not significantly different (p > 0.05). In conclusion, the MLS-FFQ was shown to be a valid tool to assess population dietary intakes.
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Kvetny, R. N., R. V. Masliy, A. M. Kyrylenko, and V. V. Shcherba. "Research of Neural Network Approach of Objects Detection in the Images." Metrology and instruments, no. 6 (January 11, 2020): 15–21. http://dx.doi.org/10.33955/2307-2180(6)2019.15-21.
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The article is devoted to the study of object detection in images using neural networks. The structure of convolutional neural networks used for image processing is considered. The formation of the convolutional layer (Fig. 1), the sub-sampling layer (Fig. 2) and the fully connected layer (Fig. 3) are described in detail. An overview of popular high-performance convolutional neural network architectures used to detect R-FCN, Yolo, Faster R-CNN, SSD, DetectNet objects has been made. The basic stages of image processing by the DetectNet neural network, which is designed to detect objects in images, are discussed. NVIDIA DIGITS was used to create and train models, and several DetectNet models were trained using this environment. The parameters of experiments (Table 1) and the comparison of the quality of the trained models (Table 2) are presented. As training and validation data, we used an image of the KITTI database, which was created to improve self-driving systems that do not go without built-in devices, one of which could be the Jetson TX2. KITTI’s images feature several object classes, including cars and pedestrians. Model training and testing was performed using a Jetson TX2 supercomputer. Five models were trained that differed in the Base learning rate parameter. The results obtained make it possible to find a compromise value for the Base learning rate parameter to quickly obtain a model with a high mAP value. The quality of the best model obtained on the KITTI validation dataset is mAP = 57.8%.
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Partanen, Jukka, Marko Kohtamäki, Vinit Parida, and Joakim Wincent. "Developing and validating a multi-dimensional scale for operationalizing industrial service offering." Journal of Business & Industrial Marketing 32, no. 2 (March 6, 2017): 295–309. http://dx.doi.org/10.1108/jbim-08-2016-0178.
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Purpose The purpose of this paper is to develop a new scale for measuring the scope (i.e. breadth and depth) of industrial service offering. Design/methodology/approach The scale and its constructs are developed by combining the key insights from prior literature and practitioners gained through expert interviews; validating the constructs by 3 item-construct validation rounds with 9 academic experts; and by testing and further revising the scale, with a sample of 91 manufacturing firms. Findings The distinct contribution of the study is the construction and validation of a new multi-dimensional scale for operationalizing the scope of industrial service offering. In addition, the identified service categories (i.e. pre-sales services, product support services, product life-cycle services, R&D services and operational services) extend the current literature on service typologies. Research limitations/implications The data are somewhat biased toward small- and medium-sized industrial firms. Hence, the development of the measurement in the context of large industrial firms provides one fruitful avenue for further research. Practical implications For managers of industrial firms, the identified service categories provide novel insight on how to develop, bundle and commercialize industrial services to their varying customer segments. Originality/value This study develops a multi-dimensional, fine-grained, statistical and relationship-level scale for measuring the scope of industrial service business. Moreover, this study tests and further develops the scale with quantitative empirical data.
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Tangio, Julhim S., Rusmiyati Patilima, Jafar La Kilo, and Akram La Kilo. "Learning Media Design based on Traditional Game of Tumbu-Tumbu Belanga (T2B) on Salt Hydrolysis Topic." JCER (Journal of Chemistry Education Research) 5, no. 1 (June 29, 2021): 32. http://dx.doi.org/10.26740/jcer.v5n1.p32-40.
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This research aimed to test the validity of the feasibility of traditional game learning media on salt hydrolysis. This research was development research (R&D) with a qualitative descriptive approach. This research uses the ADDIE model development design, which consists of 5 (five) stages, namely (1) analysis, (2) design, (3) development, (4) implementation, and (5) evaluation. Data collection techniques in this study used a validation sheet for the assessment of the feasibility of tumbu-tumbu learning media. The tumbu-tumbu learning media validation wass assessed by 4 expert validators, namely 2 chemistry lecturers of State University of Gorontalo material experts, 1 media expert lecturer, and 1 high school chemistry teacher. The results of the validation of tumbu-tumbu learning media development obtained an average percentage 0f 89.40%, which was categorized in very feasible criteria. Therefore, the tumbu-tumbu learning media are highly usable in the learning process of salt hydrolysis.
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Yulianti, Dwi, Supriadi Supriadi, Bambang Riadi, and Munaris Munaris. "Pengembangan Media Pembelajaran Baca Tulis Permulaan Berlandaskan Karakteristik Siswa." JTP - Jurnal Teknologi Pendidikan 20, no. 3 (December 31, 2018): 199–217. http://dx.doi.org/10.21009/jtp.v20i3.9535.
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The purpose of this study is to develop preliminary reading and writing teaching media for the first (1st) grade elementary school students. The method used in this study is the Research and Development (R & D) approach. The results of the study were obtained from the first level of reading and writing teaching media, level 2 and level 3. The results of learning media have undergone various validation tests and shown learning effectiveness. Content validation test results obtained mean rating 4.18, which means the media content is very valid. Language validation test results obtained 4.24 which means that the language of learning media is very good. Design validation results obtained 4.34, which means the teaching media design is very good. The effectiveness data shown that preliminary reading and writing teaching media has mean of 40.75 at 3≤ R˂4, which means that the preliminary reading and writing teaching media categorized as very effective in facilitating students to learn how to read and how to write at the beginning.
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Guillot, A., T. Moutakanni, M. Harris, P. J. Arnal, and V. Thorey. "0616 Validation of a Sleep Headband for Detecting Obstructive Sleep Apnea." Sleep 43, Supplement_1 (April 2020): A236. http://dx.doi.org/10.1093/sleep/zsaa056.613.
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Abstract Introduction Polysomnography (PSG) is the gold-standard to diagnose obstructive sleep apnea (OSA). OSA severity diagnosis is defined by the apnea-hypopnea index (AHI) defined as the number of apnea and hypopnea events measured per hour of sleep. The Dreem2 headband (DH) is a self-administered, easy to use device that measure EEG, breathing frequency, heart rate and sound at-home. In our study, we assessed the performance of the DH to automatically detects OSA compared to 3 sleep’s experts scoring on PSG. Methods 41 subjects (8 females, 42.6 ± 13.7 y.o.) having a suspicion of OSA performed a night at-home wearing both a PSG and the DH. Each PSG record was scored for apnea and hypopnea events by 3 independent trained sleep experts following AASM guidelines. The deep learning approach DOSED, was trained on the DH signals using the manual apnea scoring. 10-fold cross-validation was used to provide predictions for each of the 41 subjects with the DH. Results We observed an average AHI expert’s scoring of 13.6 ± 10.1 CI[10.5, 16.5] compared to 12.9 ± 10.3 CI[9.6, 15.8] for the DH. Both, the correlation between the 3 scorers (r= 0.88, p < 0.001) and the DH and the scorers (r=0.79, p< 0.001) were significant. The specificity and sensitivity to detect mild OSA (AHI ≤ 5) was 84.4 % and 96.4 % for the DH and 86.5 % and 86.0% for the scorers. Conclusion The results show that the DH using deep learning can detect OSA with an accuracy similar to the sleep experts. The use of DH paves the way for longitudinal monitoring of patients with a suspicion of OSA and its accessibility could lead to better screening of the general population. Support This Study has been supported by Dreem sas.
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Putri, Dinda Karunia, and Rusmini Rusmini. "Hydrocarbon and Petroleum with SETS Approach Module to Train Students’ Critical Thinking Skills." Indonesian Journal of Science and Mathematics Education 4, no. 1 (March 13, 2021): 12–24. http://dx.doi.org/10.24042/ijsme.v4i1.7839.
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The aim of this study was to develop a module with the Science, Environment, Technology and Society (SETS) approach to train critical thinking skills on hydrocarbons and petroleum using the Research and Development (R and D) method. This development modul was validated by 3 experts, while the limited trial was only limited to a small trial with 3 respondents from class XII students of SMAN 10 Surabaya to obtain practical and effective data of modules that developed on a small scale. This experiment obtained expert validation results 87% with the “very valid” category, module practicality 94% with the “very practical” category and module effectiveness of 0.8 with the “high” category. The effectiveness of the module is obtained from the pretest and posttest that 3 students have increased their critical thinking skills after the module is given. Based on this study, it can be concluded that the module with the SETS approach in the material of hydrocarbons and petroleum can train students’ critical thinking skills and it is feasible to be tested on larger respondents.
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Sarjono Owon, Robertus Adi. "Pengembangan Bahan Ajar Menulis Berbagai Jenis Teks Bertema Kearifan Lokal Sikka Bagi Siswa SMP." JINoP (Jurnal Inovasi Pembelajaran) 3, no. 1 (May 26, 2017): 528. http://dx.doi.org/10.22219/jinop.v3i1.4318.
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AbstrakMenulis merupakan keterampilan berbahasa yang diajarkan secara terpadu dengan ketiga keterampilan berbahasa lainnya.Dalam kurikulum 2013, pembelajaran yang dilakukan berbasis teks, tetapi sumber bahan ajar masih terbatas pada buku siswa terbitan Depdiknas.Oleh karena itu, perlu dikembangkan bahan ajar menulis berbagai jenis teks bertema kearifan lokal dengan pendekatan kontekstual bagi siswa SMP. Penelitian ini bertujuan untuk (1) menghasilkan prototipe bahan ajar menulis berbagai jenis teks bertema kearifan lokal Sikka dengan pendekatan kontekstual sesuai kebutuhan peserta didik dan guru, (2) menguji hasil kelayakan prototipe bahan ajar menulis berbagai jenis teks bertema kearifan lokal Sikka dari segi bentuk dan isi, dan (3) menguji efektivitas bahan ajar menulis dalam meningkatkan kemampuan menulis peserta didik.Jenis penelitian yang digunakan adalah penelitian dan pengembangan (R&D). Data berupa kebutuhan bahan ajar menulis, produk prototipe bahan ajar, dan tulisan siswa. Sumber data berasal dari siswa, guru, budayawan Sikka, dan ahli.Hasil penelitian ini menunjukkan bahwa (1) Prototipe bahan ajar menulis berbagai jenis teks bermuatan kearifan lokal Sikka dengan pendekatan kontekstual sesuai kebutuhan peserta didik dan guru meliputi model teks, struktur teks, strategi pengembangan tulisan, latihan soal, pedoman penilaian dan suplemen berupa EYD. Adapun pendekatan kontekstual terintegrasi dalam proses pembelajaran. (2) Hasil penilaian validator ahli dengan rerata skor 77,45 atau Layak, sedangkan validator pengguna dengan rerata skor 85, 53 atau Amat Layak. (3) Hasil uji efektivitas menunjukkan bahwa bahan ajar menulis teks secara efektif dapat meningkatkan kemampuan menulis peserta didik ditandai dengan persentasi daya serap mencapai 80% secara kelompok dan 80% siswa mampu mengembangkan teks sesuai dengan struktur, isi, ejaan, tanda baca, dan penggunaan huruf kapital.Kata Kunci: bahan ajar, jenis teks, kearifan lokal ABSTRACWriting is language skills in which integrated preached with the third other skills. In curriculum 2013, the learning done based on the text, but the sources of teaching materials still limited on students’ book published by Department of Education National. So that, it’s needed to developed teaching materials Writing Various Type of Text Themed Local Wisdom of Sikka Regency, NTT by Using Contextual Approach for The Junior High School Student. This research is aims to (1) identify prototype teaching materials writing various type of text themed Sikka local wisdom as students’ and teacher’s needed, (2) knowing the result of prototype expediency writing various type themed Sikka local wisdom in terms of and the contents of, and (3) knowing the effectiveness writing teaching materials to improving the learner’s ability in writing.This research is R& D. The data are collected by using questionnaire to identifies the necessity of teaching materials and to examine prototype expediency of teaching materials. Besides the data also are collected from Students’ result of study toward the ability in writing text themed Sikka local wisdom to examine effectiveness of product.This research indicates that (1) prototype teaching materials writing various type of text themed Sikka local wisdom by using contextual approach based on students’ and teacher’s necessity included: text model, structure of the text, strategy of writing development, exercises, rating directive and supplement EYD. There is also contextual approach integrated in learning process, (2) the rating result of validation expert on the average score is 77, 45 (good) mean while the rating result of validation user average score is 85, 53 (excellent) and (3) teaching materials writing text effectively can develop the ability of students’ writing shown by the percentage of students’ classical completeness 80% in groups and 80% students can develop the text based on structure, content, spelling, punctuations and the use of capital letter.Key words: teaching materials, kinds of text, local wisdom, contextual approach
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Murti, Sri, and Dian Ramadan Lazuardi. "Pengembangan Bahan Ajar Mata Kuliah Konsep Dasar Bahasa dan Sastra Indonesia Berbasis Kontekstual STKIP PGRI Lubuklinggau." Jurnal Kajian Bahasa, Sastra dan Pengajaran (KIBASP) 3, no. 1 (December 23, 2019): 1–16. http://dx.doi.org/10.31539/kibasp.v3i1.972.
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This study aims to determine the design of instructional materials development, validation results, and effectiveness of the use of contextual basic concepts of indonesian language and literature in STKIP PGRI Lubuklinggau students. This research uses the R&D (research and development) approach of the Borg and Gall model. The steps of development that researchers do namely, preliminary research, planning development models, validation, evaluation, and revision of the model. Furthermore, teaching material products are tested on students with the steps: 1) Portotype testing, 2) Initial input, 3) Small group testing, 4) Field testing. Based on the results of the validation of three experts regarding the teaching materials of the basic concepts of indonesian language and literature, the results obtained by 80%, the teaching materials are in good category. The results of this study also showed that contextual based indonesian conceptual language and literature teaching materials were effectively used in lectures.
Keywords: Teaching Materials, Contextual, Basic Concepts
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Rumahorbo, Shinta, and Nurfajriani Nurfajriani. "Pengembangan Media E-Learning Berbasis Weblog dengan Pendekatan Contextual Teaching and Learning (CTL) pada Materi Laju Reaksi." Jurnal Indonesia Sosial Sains 3, no. 4 (April 21, 2022): 615–24. http://dx.doi.org/10.36418/jiss.v3i4.566.
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This study aims to find out the analysis of media needs, look for e-learning media based on weblogs with a CTL approach on reaction rates developed based on BSNP and knowing students' responses to webblog-based e-learning media with a CTL approach on the reaction rate material. Analysis of media needs was carried out by interviewing the chemistry class teacher of SMAN 1 Sibolga. This study uses the method (R&D) with the ADDIE development model covering the stages (analysis, design, development, implementation and evaluation). The developed media product was validated by 3 expert validators consisting of 2 chemistry lecturers and 1 chemistry teacher. The average result of the validation of the weblog-based e-learning media with the CTL approach that has been developed by chemistry lecturers and teachers is 3.70 in the very feasible category and material validation is 3.71 in the very feasible category and does not need to be revised. The assessment of the percentage of student responses to the web-based e-learning media developed was 74.5% with high response criteria
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Nedelec, Bernadette, Jocelyn Chen, Cassandra Caluori, Laura Alberton, Jinny Zhang, Danielle Shashoua, Valérie Calva, Nathalie Gauthier, Ana de Oliveira, and Elisabeth Marois-Pagé. "T4 Validation of the Burn Survivor Fear-avoidance Questionnaire." Journal of Burn Care & Research 43, Supplement_1 (March 23, 2022): S3—S4. http://dx.doi.org/10.1093/jbcr/irac012.003.
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Abstract Introduction According to the Fear-Avoidance (FA) Model, FA beliefs can lead to disability due to avoidance of activities expected to result in pain or further injury. Extensive research on the relationship of FA, pain, catastrophizing, and disability has been generated with patients suffering from chronic neck and back pain, but little research has been conducted with burn survivors. To address the need for a valid evaluation of FA in burn survivors, Langlois and colleagues developed, but did not validate, the Burn Survivor Fear-Avoidance Questionnaire (BSFAQ). Thus, the primary objective of this study was to investigate the construct validity of the BSFAQ among burn survivors. The secondary objective was to examine the relationship between FA and (i) pain intensity and (ii) catastrophizing at baseline (admission to rehab), 3 months and 6 months post-burn, and (iii) disability among burn survivors at 6 months post-burn. Methods A prospective mixed methods approach was used to examine the construct validity by comparing the quantitative scores of the BSFAQ to independently performed qualitative interviews of burn survivors (n=31) that explored their lived-experiences, to determine if the BSFAQ discriminated those who had, from those who did not have FA beliefs and behaviors. Data for the secondary objective, scores of burn survivors (n=51) pain intensity (measured by the Numeric Rating Scale), catastrophizing (measured by the Pain Catastrophizing Scale), and disability (measured by the Burn Specific Health Scale-brief), were collected through a retrospective chart review. Results For the primary objective, Wilcoxon Rank Sum Test results showed a statistically significant difference (p=0.015) between the BSFAQ scores of participants who were identified from the qualitative interviews as fear-avoidant compared to those who were identified as non-fear-avoidant. For the secondary objective, the Spearman correlation test results showed a moderate correlation between FA and (i) pain at baseline (r=0.466, p=0.002), a moderate correlation with (ii) catastrophizing thoughts over time (r=0.557, p=0.000; r=0.470, p=0.00; r=0.559, p=0.002 respectively at each time point), and a moderate correlation with (iii) disability at 6 months post-burn (r=-0.639, p=0.000). Conclusions These results support that the BSFAQ is able to discriminate which BS are experiencing fear-avoidant beliefs and behaviours. As has been reported in other patient populations, burn survivors who express FA are more likely to report higher levels of pain early during their recovery that correlates with elevated catastrophizing thoughts, which are maintained across time and ultimately results in higher self-reported disability, which is consistent with the FA model.
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Dalimunthe, Makharany, and Randika Janama Ginting. "Pengembangan Modul Berbasis Problem Based Learning dengan Pendekatan Saintifik pada Materi Asam-Basa." Jurnal Inovasi Pembelajaran Kimia 4, no. 2 (October 31, 2022): 177. http://dx.doi.org/10.24114/jipk.v4i2.38991.
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This study aims to (1) determine the level of validation of the learning module on the acid-base subject developed based on PBL with a scientific approach, (2) knowing student learning outcomes on PBL-based learning modules with a scientific approach on the subject of acid-base, and (3) determine student responses to the PBL based learning module with a scientific approach. on the subject of acid-base. This study uses the method (R&D) with the application of the ADDIE model at each stage. Based on the research results, the product that has been developed is validated by 3 expert validators consisting of 2 lecturers and 1 chemistry teacher. The average result of the module analysis based on PBL with a scientific approach carried out by chemistry lecturers and teachers that has been developed is ± 3,26. Student learning outcomes increased to 75.43% with a maximum score of 100 and a minimum of 75 and the average of posttest of ± 86>KKM value of 75. Hypothesis testing using hypothesis testing resulted in tcount > ttable, namely 12.36>1,69. Based on the assessment of the percentage level of student response to the module that has been developed, it is 71,31 and is categorized as high enough.Penelitian ini bertujuan untuk (1) mengetahui tingkat validasi modul pembelajaran pada mata pelajaran asam-basa yang dikembangkan berbasis PBL dengan pendekatan saintifik, (2) mengetahui hasil belajar siswa pada modul pembelajaran berbasis PBM dengan pendekatan saintifik pada mata pelajaran asam-basa, dan (3) mengetahui respon siswa terhadap modul pembelajaran berbasis PBL dengan pendekatan saintifik. pada materi asam-basa. Penelitian ini menggunakan metode (R&D) dengan penerapan model ADDIE pada setiap tahapannya. Berdasarkan hasil penelitian, produk yang telah dikembangkan divalidasi oleh 3 validator ahli yang terdiri dari 2 orang dosen dan 1 orang guru kimia. Rata-rata hasil analisis modul berbasis PBL dengan pendekatan saintifik yang dilakukan oleh dosen dan guru kimia yang telah dikembangkan adalah ± 3,26 , sehingga modul ini sangat layak digunakan. Hasil belajar siswa meningkat menjadi 75,43% dengan nilai maksimal 100 dan minimal 75 serta rata-rata posttest ± 86 > nilai KKM 75. Pengujian hipotesis dengan menggunakan pengujian hipotesis diperoleh nilai thitung > ttabel yaitu 12,36 > 1,69 , Sehingga penelitian ini menyimpulkan bahwa Ha diterima yaitu hasil belajar siswa dengan menggunakan modul yang telah dikembangkan lebih besar daripada KKM. Berdasarkan penilaian persentase respon siswa terhadap modul yang telah dikembangkan sebesar 71,31 dan dikategorikan cukup tinggi.
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Frobel, Joana, Tanja Božić, Michael Lenz, Peter Uciechowski, Yang Han, Reinhild Herwartz, Klaus Strathmann, et al. "Leukocyte Counts Based on DNA Methylation at Individual Cytosines." Clinical Chemistry 64, no. 3 (March 1, 2018): 566–75. http://dx.doi.org/10.1373/clinchem.2017.279935.
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Abstract BACKGROUND White blood cell counts are routinely measured with automated hematology analyzers, by flow cytometry, or by manual counting. Here, we introduce an alternative approach based on DNA methylation (DNAm) at individual CG dinucleotides (CpGs). METHODS We identified candidate CpGs that were nonmethylated in specific leukocyte subsets. DNAm levels (ranging from 0% to 100%) were analyzed by pyrosequencing and implemented into deconvolution algorithms to determine the relative composition of leukocytes. For absolute quantification of cell numbers, samples were supplemented with a nonmethylated reference DNA. RESULTS Conventional blood counts correlated with DNAm at individual CpGs for granulocytes (r = −0.91), lymphocytes (r = −0.91), monocytes (r = −0.74), natural killer (NK) cells (r = −0.30), T cells (r = −0.73), CD4+ T cells (r = −0.41), CD8+ T cells (r = −0.88), and B cells (r = −0.66). Combination of these DNAm measurements into the “Epi-Blood-Count” provided similar precision as conventional methods in various independent validation sets. The method was also applicable to blood samples that were stored at 4 °C for 7 days or at −20 °C for 3 months. Furthermore, absolute cell numbers could be determined in frozen blood samples upon addition of a reference DNA, and the results correlated with measurements of automated analyzers in fresh aliquots (r = 0.84). CONCLUSIONS White blood cell counts can be reliably determined by site-specific DNAm analysis. This approach is applicable to very small blood volumes and frozen samples, and it allows for more standardized and cost-effective analysis in clinical application.
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Hamsyah, Devitia, Lesy Luzyawati, and Eva Yuliana. "Validitas Instrumen Penalaran Ilmiah pada Materi Sistem Pertahanan Tubuh Kelas XI." Quagga: Jurnal Pendidikan dan Biologi 13, no. 1 (December 31, 2020): 26. http://dx.doi.org/10.25134/quagga.v13i1.3474.
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Abstrak: Pada abad ke 21 kemampuan bernalar merupakan kemampuan yang harus dimiliki siswa dalam memecahkan permasalahan dan proses pembelajaran harus dapat menilai penalaran ilmiah siswa. Akan tetapi hasil lapangan menemukan bahwa pada beberapa guru biologi belum pernah melakukan penilaian penalaran ilmiah pada siswa, sehingga penelitian ini akan mengembangkan instrumen penalaran ilmiah pada materi sistem pertahanan tubuh. Tujuan penelitian ini adalah untuk mengetahui validitas produk instrumen penalaran ilmiah. Jenis penelitian ini adalah penelitian pengembangan (R&D) dengan pendekatan model 4 D (Define, Design, Develop and Dessiminate). Populasi sampel yang diambil dalam penelitian ini adalah 5 validator yang terdiri dari 3 Dosen sebagai ahli penalaran ilmiah, ahli materi dan 2 Guru praktisi. Teknik pengambilan sampel menggunakan purposive sample. Teknik pengumpulan data menggunakan lembar validasi dan lembar wawancara. Hasil validasi yang dilakukan dua kali berada pada kategori validitas sangat tinggi, hal ini menunjukan bahwa produk instrumen penalaran ilmiah pada materi sistem pertahanan tubuh kelas XI yang peneliti kembangkan layak untuk digunakan.Kata Kunci: Instrumen penilaian; penalaran ilmiah; sistem pertahanan tubuh�Abstract: In the 21st century the ability to reason is an ability that students must have in solving problems. In this case the learning process must be able to assess students' scientific reasoning. However, the field results found that some biology teachers have never conducted scientific reasoning assessments on students, so this research will develop scientific reasoning instruments on the body's defense system material. The purpose of this study was to determine the product validity of scientific reasoning instruments. Type of research is development research (R&D) with a 4 D model approach (Define, Design, Develop and Dessiminate). The sample population taken in this study were 5 validators consisting of 3 lecturers as scientific reasoning experts, material experts and 2 teacher practitioners. The sampling technique used purposive sample. Data collection techniques using validation sheets and interview sheets. The results of the validation that were carried out twice were in the very high validity category, This shows that the product of scientific reasoning instruments in the class XI body defense system material that the researcher developed is suitable for use.Keywords: Assessment instrument; scientific reasoning; body defense system
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Guevara, Mario, Michela Taufer, and Rodrigo Vargas. "Gap-free global annual soil moisture: 15 km grids for 1991–2018." Earth System Science Data 13, no. 4 (April 27, 2021): 1711–35. http://dx.doi.org/10.5194/essd-13-1711-2021.
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Abstract. Soil moisture is key for understanding soil–plant–atmosphere interactions. We provide a soil moisture pattern recognition framework to increase the spatial resolution and fill gaps of the ESA-CCI (European Space Agency Climate Change Initiative v4.5) soil moisture dataset, which contains > 40 years of satellite soil moisture global grids with a spatial resolution of ∼ 27 km. We use terrain parameters coupled with bioclimatic and soil type information to predict finer-grained (i.e., downscaled) satellite soil moisture. We assess the impact of terrain parameters on the prediction accuracy by cross-validating downscaled soil moisture with and without the support of bioclimatic and soil type information. The outcome is a dataset of gap-free global mean annual soil moisture predictions and associated prediction variances for 28 years (1991–2018) across 15 km grids. We use independent in situ records from the International Soil Moisture Network (ISMN, 987 stations) and in situ precipitation records (171 additional stations) only for evaluating the new dataset. Cross-validated correlation between observed and predicted soil moisture values varies from r= 0.69 to r= 0.87 with root mean squared errors (RMSEs, m3 m−3) around 0.03 and 0.04. Our soil moisture predictions improve (a) the correlation with the ISMN (when compared with the original ESA-CCI dataset) from r= 0.30 (RMSE = 0.09, unbiased RMSE (ubRMSE) = 0.37) to r= 0.66 (RMSE = 0.05, ubRMSE = 0.18) and (b) the correlation with local precipitation records across boreal (from r= < 0.3 up to r= 0.49) or tropical areas (from r= < 0.3 to r= 0.46) which are currently poorly represented in the ISMN. Temporal trends show a decline of global annual soil moisture using (a) data from the ISMN (-1.5[-1.8,-1.24] %), (b) associated locations from the original ESA-CCI dataset (-0.87[-1.54,-0.17] %), (c) associated locations from predictions based on terrain parameters (-0.85[-1.01,-0.49] %), and (d) associated locations from predictions including bioclimatic and soil type information (-0.68[-0.91,-0.45] %). We provide a new soil moisture dataset that has no gaps and higher granularity together with validation methods and a modeling approach that can be applied worldwide (Guevara et al., 2020, https://doi.org/10.4211/hs.9f981ae4e68b4f529cdd7a5c9013e27e).
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Larasati, Fransiska Angela, and Nida Yanti. "PENGEMBANGAN BAHAN AJAR TEKS NEGOSIASI DENGAN PENDEKATAN KONTRUKTIVISME BERBASIS KECAKAPAN PERSONAL PADA SISWA." PENTAS : Jurnal Ilmiah Pendidikan Bahasa dan Sastra Indonesia 7, no. 2 (November 30, 2021): 47–58. http://dx.doi.org/10.52166/pentas.v7i2.3099.
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Based on this background, the objectives of this study are as follows (1) to determine, (2) to determine practicality, and (3) to determine the effectiveness of Negotiation Text teaching materials with a constructivism approach based on personal skills in class X SMA Persatuan Kedungpring Lamongan. Based on the process of developing teaching materials, there are steps (1) designing teaching materials, (2) expert validation, (3) design improvements, and (4) product trials. The researchers used research and development (R&D) methods. The model for developing teaching materials uses the Borg & Gall model which is adapted to the Constructivism approach. The research subjects were selected according to the needs, namely, (1) expert on validity, (2) expert on practitioner, (3) expert on effectiveness. The type of data selected is the result of validity from experts on validity, expert practitioners, and experts on effectiveness with experimental methods.
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Medveďová, A., Ľ. Valík, Z. Sirotná, and D. Liptáková. "Growth characterisation of Staphylococcus aureus in milk: a quantitative approach." Czech Journal of Food Sciences 27, No. 6 (December 23, 2009): 433–53. http://dx.doi.org/10.17221/24/2009-cjfs.
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<i>Staphylococcus aureus</i> is a pathogenic bacterium that induces several of human illnesses. The staphylococcal enterotoxin (SE) production as the results of previous growth of toxigenic strains is the most crucial problem which may lead to the staphylococcal food poisoning outbreaks in humans. That is why the growth of three strains of <i>Staphylococcus aureus</i> was characterised in milk and modelled in dependence of temperature. For the lag phase duration of <i>S. aureus</i> 2064, the Davey model was used with the following result: ln(1/lag) = 1.973 – 87.92/<i>T</i> + 285.09/<i>T</i><sup>2</sup> (<i>R</i><sup>2</sup> = 0.962). The dependence of the growth rate on incubation temperature was modelled by the Ratkowsky square root model and Gibson in sub-optimal and whole temperature range, respectively. The validation of both models showed high significance of the growth rate data fitting. The optimal temperature of <i>T</i><sub>opt</sub> = 38.5°C was resulted from Gibson model for the <i>S. aureus</i> 2064 growth in milk. For practical purpose, the time necessary for the increase of <i>S. aureus</i> by 3 log counts was also calculated within the growth temperature range. These data may provide useful information e.g. for the producers using raw milk in their artisanal cheese practice as the specific strains were used in this study.
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Djibu, Rusdin, and Imam Shofwan. "Development of model training mentoring in improving assistant competence in the convection group of businesses." JPPM (Jurnal Pendidikan dan Pemberdayaan Masyarakat) 6, no. 2 (December 5, 2019): 131–39. http://dx.doi.org/10.21831/jppm.v6i2.27432.
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This research aims to develop a mentoring training model to improve the competence of the assistant in the convection group in the city of Gorontalo. The approach used in this research is qualitative. The methods used are research and development (R D) which include the following activities: (1) Preliminary review of the initial condition of competence of convection assistants, (2) Development model Mentoring, (3) expert validation and revision, (4) implementation of the model , (5) test the effectiveness of the model, and (6) model recommendation. The results of Development Studies show: (1) initial condition of convection competence of the general do not follow the standards of convection assistant, because the convection assistant has not received training, (2) The development of training model mentoring to Increase the competence of convection assistants conducted through several steps; Conducting analysis of development needs, determining the elements to be developed, developing a mentoring model to improve quality and productivity, validating model development with non-formal education experts, educational practitioners Non-formal and peer, and compile the final model, (3) Implication model assistance is conducted thorough testing and testing model assistance. All these activities are done through stages; Planning, organizing, implementing, evaluating, and delivering results. (4) The development of a training model affects the effectiveness and efficiency of training implementation. Effectiveness tests are conducted through post-test. Research findings suggest that the training model of mentoring to improve the competencies developed by the convection Assistant is recommended for the interested parties.
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Pedersen, Line Kjeldgaard, Ole Rahbek, Lone Nikolajsen, and Bjarne Møller-Madsen. "The revised FLACC score: Reliability and validation for pain assessment in children with cerebral palsy." Scandinavian Journal of Pain 9, no. 1 (October 1, 2015): 57–61. http://dx.doi.org/10.1016/j.sjpain.2015.06.007.
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AbstractBackground and aimsPain in children with cerebral palsy (CP) is difficult to assess and is therefore not sufficiently recognized and treated. Children with severe cognitive impairments have an increased risk of neglected postoperative, procedural and chronic pain resulting in decreased quality of life. The r-FLACC (revised Face, Legs, Activity, Cry and Consol ability) pain score is an internationally acclaimed tool for assessing pain in children with CP because of its ease to use and its use of core pain behaviours. In addition the r-FLACC pain score may be superior to other pain assessment tools since it includes an open- ended descriptor for incorporation of individual pain behaviours. The COSMIN group has set up three quality domains, which describe the quality of Health-Related Patient-Reported Outcomes (HR-PROs). These are reliability (internal consistency, reliability and measurement error), validity (content validity, construct validity and criterion validity) and responsiveness. The r-FLACC score has only been assessed for reliability and validity in the original English version by the developers of the score. The aim of this study is to assess reliability and validity of the r-FLACC pain score for use in Danish children with CP.MethodsTwenty-seven children aged 3–15 years old with CP were included after orthopaedic surgery. Two methods for assessment of postoperative pain were used. Pain intensity was assessed by r-FLACC, with a 2 min standardized video recording of the child, and the Observational Visual Analogue Score (VAS-OBS) assessed by the parents. The COSMIN checklist was used as a guideline in the reliability and validity testing of the r-FLACC score.ResultsReliability was supported by three measurement properties. Internal consistency was excellent with a Cronbachs alpha of 0.9023 and 0.9758 (two raters). A factor analysis of the subgroups in the r-FLACC score showed unidimensionality. A test-retest showed excellent intra-rater reliability with an intraclass correlation (ICC) of 0.97530. Inter-rater reliability was acceptable with an ICC of 0.74576. Validity was supported by three measurement properties. Content validity was tested by the originators of the r-FLACC. Construct validity was supported by a significant increase in r-FLACC scores following surgery (n = 17; difference 2.23; p = 0.0397). Criterion validity was acceptable with Pearson’s correlation coefficients of 0.76 and 0.59 when comparing r-FLACC scores and VAS-OBS scores.Conclusions and implicationsThis study benefits from a systematical approach to the validation and reliability parameters by using the COSMIN checklist as a guideline. It is evident that the r-FLACC pain score maintains its psychometric properties after translation. In conclusion, the r-FLACC pain score is valid and reliable in assessing postoperative pain in children with CP not able to self-report pain. With the r-FLACC pain score clinicians have a valid tool for assessing postoperative pain, hence increasing the quality of pain management in children with CP. In addition the validated r-FLACC score has the potential for use in interventional research regarding pain management in this vulnerable group of patients. Future perspectives include validation of the r-FLACC score for procedural and chronic everyday pain and implementation into daily practice.
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Saafi, Houssem, Med Amine Laribi, and Said Zeghloul. "Forward Kinematic Model Resolution of a Special Spherical Parallel Manipulator: Comparison and Real-Time Validation." Robotics 9, no. 3 (August 6, 2020): 62. http://dx.doi.org/10.3390/robotics9030062.
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This paper deals with a special architecture of Spherical Parallel Manipulators (SPMs) designed to be a haptic device for a medical tele-operation system. This architecture is obtained by replacing the kinematic of one leg of a classical 3-RRR SPM (R for revolute joint). The Forward Kinematic Model (FKM) is particularly addressed to allow the new master device to control the motion of a slave surgical robot. For this purpose, three methods are presented to solve the FKM and compared based on the criterion of time consuming and accuracy. For each method, namely, classic FKM, Improved method and serial FKM, the resolution procedure is detailed and the experimental validation is presented. After comparison, the serial approach involving the use of three sensors located on one leg of the master device is revealed as the most suitable. Experimental validation of the real-time motion control is successfully performed using the serial FKM.
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Paolini, Giovanni, Maria Jose Escorihuela, Joaquim Bellvert, and Olivier Merlin. "Disaggregation of SMAP Soil Moisture at 20 m Resolution: Validation and Sub-Field Scale Analysis." Remote Sensing 14, no. 1 (December 31, 2021): 167. http://dx.doi.org/10.3390/rs14010167.
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This paper introduces a modified version of the DisPATCh (Disaggregation based on Physical And Theoretical scale Change) algorithm to disaggregate an SMAP surface soil moisture (SSM) product at a 20 m spatial resolution, through the use of sharpened Sentinel-3 land surface temperature (LST) data. Using sharpened LST as a high resolution proxy of SSM is a novel approach that needs to be validated and can be employed in a variety of applications that currently lack in a product with a similar high spatio-temporal resolution. The proposed high resolution SSM product was validated against available in situ data for two different fields, and it was also compared with two coarser DisPATCh products produced, disaggregating SMAP through the use of an LST at 1 km from Sentinel-3 and MODIS. From the correlation between in situ data and disaggregated SSM products, a general improvement was found in terms of Pearson’s correlation coefficient (R) for the proposed high resolution product with respect to the two products at 1 km. For the first field analyzed, R was equal to 0.47 when considering the 20 m product, an improvement compared to the 0.28 and 0.39 for the 1 km products. The improvement was especially noticeable during the summer season, in which it was only possible to successfully capture field-specific irrigation practices at the 20 m resolution. For the second field, R was 0.31 for the 20 m product, also an improvement compared to the 0.21 and 0.23 for the 1 km product. Additionally, the new product was able to depict SSM spatial variability at a sub-field scale and a validation analysis is also proposed at this scale. The main advantage of the proposed product is its very high spatio-temporal resolution, which opens up new opportunities to apply remotely sensed SSM data in disciplines that require fine spatial scales, such as agriculture and water management.
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Torabi, Seyed Alireza, Reza Mastouri, and Mohsen Najarchi. "Daily flow forecasting of perennial rivers in an arid watershed: a hybrid ensemble decomposition approach integrated with computational intelligence techniques." Journal of Water Supply: Research and Technology-Aqua 69, no. 6 (March 25, 2020): 555–77. http://dx.doi.org/10.2166/aqua.2020.138.
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Abstract Accurate estimating of daily streamflow forecasting is one of the prominent topics in water resources activities. In this paper, an integrated method including decomposition technique based on the ensemble empirical mode decomposition (EEMD) combined with multivariate adaptive regression spline (MARS) was carried out to predict daily streamflow values. Daily streamflow value datasets collected from two stations in Iran (Gachsar and Kordkheyl) were selected. After dividing into calibration and validation datasets, each of them was decomposed by EEMD. Crow search algorithm (CSA) was used to optimize the MARS parameters (MARS-CSA). The performance of the integrated model (EEMD-MARS-CSA) was investigated by error indices (correlation coefficient (R), root mean squared error (RMSE), mean absolute error (MAE), Nash–Sutcliffe efficiency (NSE), as well as RMSE to standard deviation ratio (RSR)). From the results, EEMD was an important tool for increasing model accuracy and EEMD-MARS-CSA outperformed other alternative methods for daily streamflow estimation. According to one-day-ahead flow forecasting, EEMD-MARS-CSA (R = 0.94, RMSE = 5.94 m3/s (Kordkheyl) and R = 0.98, RMSE = 0.71 m3/s (Gachsar)) outperformed EEMD-MT/MARS, MT, and MARS models. Furthermore, RSR criterion of EEMD-MARS-CSA was reduced by 18%, 16%, and 17% for 3-days, 1-week, and 2-weeks-ahead streamflow forecasting compared to MARS-CSA model, respectively, for Gachsar station.
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Ahmad, Wan Muhamad Amir W., Muhammad Azeem Yaqoob, Nor Farid Mohd Noor, Farah Muna Mohamad Ghazali, Nuzlinda Abdul Rahman, Liszen Tang, Nor Azlida Aleng, and Mohammad Khursheed Alam. "The Predictive Model of Oral Squamous Cell Survival Carcinoma: A Methodology of Validation." BioMed Research International 2021 (November 25, 2021): 1–6. http://dx.doi.org/10.1155/2021/5436894.
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Background. Cancer is primarily caused by smoking, alcohol, betel quit, a series of genetic alterations, and epigenetic abnormalities in signaling pathways, which result in a variety of phenotypes that favor the development of OSCC. Oral squamous cell carcinoma (OSCC) is the most common type of oral cancer, accounting for 80–90% of all oral malignant neoplasms. Oral cancer is relatively common, and it is frequently curable when detected and treated early enough. The tumor-node-metastasis (TNM) staging system is used to determine patient prognosis; however, geographical inaccuracies frequently occur, affecting management. Objective. To determine the additional relationship between factors discovered by searching for sociodemographic and metastasis factors, as well as treatment outcomes, which could help improve the prediction of the survival rate in cancer patients. Material and Methods. A total of 56 patients were recruited from the ambulatory clinic at the Hospital Universiti Sains Malaysia (USM). In this retrospective study, advanced computational statistical modeling techniques were used to evaluate data descriptions of several variables such as treatment, age, and distant metastasis. The R-Studio software and syntax were used to implement and test the hazard ratio. The statistics for each sample were calculated using a combination model that included methods such as bootstrap and multiple linear regression (MLR). Results. The statistical strategy showed R demonstrates that regression modeling outperforms an R-squared. It demonstrated that when data is partitioned into a training and testing dataset, the hybrid model technique performs better at predicting the outcome. The variable validation was determined using the well-established bootstrap-integrated MLR technique. In this case, three variables are considered: age, treatment, and distant metastases. It is important to note that three things affect the hazard ratio: age ( β 1 : -0.006423; p < 2 e − 16 ), treatment ( β 2 : -0.355389; p < 2 e − 16 ), and distant metastasis ( β 3 : -0.355389; p < 2 e − 16 ). There is a 0.003469102 MSE for the linear model in this scenario. Conclusion. In this study, a hybrid approach combining bootstrapping and multiple linear regression will be developed and extensively tested. The R syntax for this methodology was designed to ensure that the researcher completely understood the illustration. In this case, a hybrid model demonstrates how this critical conclusion enables us to better understand the utility and relative contribution of the hybrid method to the outcome. The statistical technique used in this study, R, demonstrates that regression modeling outperforms R-squared values of 0.9014 and 0.00882 for the predicted mean squared error, respectively. The conclusion of the study establishes the superiority of the hybrid model technique used in the study.
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Kautsar, Akbarul, Giri Wiyono, Muji Mulia, Muhammad Iqbal, and Muhajir Al-Fairusy. "Teaching Factory Model Development in Vocational High Schools." AL-ISHLAH: Jurnal Pendidikan 14, no. 4 (October 6, 2022): 6347–60. http://dx.doi.org/10.35445/alishlah.v14i4.2461.
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This study aims to find a conceptual model of teaching factory in the field of air conditioning and air conditioning engineering in vocational high schools (VHS). The teaching factory development model is expected to have a solid legal foundation and be able to carry out independent financial management so that they are able to carry out sound business practices. This study uses a type of development research, namely research and development (R D), with a 4-D (Four-D) approach. The stages in this research are define, design, development, and disseminate. The conceptual model of the teaching factory was tested for feasibility by the validator of material experts (expert judgment) and the model user, namely by the executor of the teaching factory in the field of refrigeration and air conditioning engineering at VHS 1 Magelang. The results of the study indicate that the teaching factory conceptual model consists of components, namely 1) information technology; 2) PPK-BLUD; 3) HR; 4) block schedule; 5) worksheets; 6) products/services; 7) workshops; 8) industry partnerships; and 9) system management. Based on the results of expert validation and model user responses, the teaching factory conceptual model was declared feasible to be applied in VHS. The teaching factory conceptual model has a solid legal foundation, allows for independent financial management patterns, and can carry out healthy business practices on an ongoing basis (sustainability).
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Guo, Xiaotong, Dan Meng, Xuelong Chen, and Xiaojuan Li. "Validation and Comparison of Seven Land Surface Evapotranspiration Products in the Haihe River Basin, China." Remote Sensing 14, no. 17 (September 1, 2022): 4308. http://dx.doi.org/10.3390/rs14174308.
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Evapotranspiration (ET) is an important part of the surface energy balance and water balance. Due to imperfect model parameterizations and forcing data, there are still great uncertainties concerning ET products. The validation of land surface ET products has a certain research significance. In this study, two direct validation methods, including the latent heat flux (LE) from the flux towers validation method and the water balance validation method, and one indirect validation method, the three-corned hat (TCH) uncertainty analysis, were used to validate and compare seven types of ET products in the Haihe River Basin in China. The products evaluated included six ET products based on remotely-sensed observations (surface energy balance based global land evapotranspiration [EB-ET], Moderate Resolution Imaging Spectroradiometer [MODIS] global terrestrial evapotranspiration product [MOD16], Penman–Monteith–Leuning Evapotranspiration version 2 [PML_V2], Global Land Surface Satellite [GLASS], global land evaporation Amsterdam model [GLEAM], and Zhangke evapotranspiration [ZK-ET]) and one ET product from atmospheric re-analysis data (Japanese 55-year re-analysis, JRA-55). The goals of this study were to provide a reference for research on ET in the Haihe River Basin. The results indicate the following: (1) The results of the six ET products have a higher accuracy when the flux towers validation method is used. Except for MOD16_ET and EB_ET, the Pearson correlation coefficients (R) were all greater than 0.6. The root mean square deviation (RMSD) values were all less than 40 W/m2. The GLASS_ET data have the smallest average deviation (BIAS) value. Overall, the GLEAM_ET data have a higher accuracy. (2) When the validation of the water balance approach was used, the low values of the MOD16_ET were overestimated and the high values were underestimated. The values of the EB_ET, GLEAM_ET, JRA_ET, PML_ET, and ZK_ET were overestimated. According to the seasonal variations statistics, most of the ET products have higher R values in spring and lower R values in summer, and the RMSD values of most of the products were the highest in summer. (3) According to the results of the uncertainty quantification based on the TCH method, the average value of the relative uncertainties of the GLEAM_ET data were the lowest. The relative uncertainties of the JRA_ET and ZK_ET were higher in mountainous areas than in non-mountainous area, and the relative uncertainties of the PML_ET were lower in mountainous areas. The performances of the EB_ET, GLEAM_ET, and MOD16_ET in mountainous and non-mountainous areas were relatively equal. The relative uncertainties of the ET products were significantly higher in summer than in other periods, and they also varied in the different sub-basins.
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Muzzalifa, Siti, and Coryna Oktaviani. "Pengembangan Media Belajar Buletin dalam Bentuk Buku Saku pada Materi Termokimia." Indonesian Journal of Mathematics and Natural Science Education 2, no. 1 (June 29, 2021): 16–27. http://dx.doi.org/10.35719/mass.v2i1.52.
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Penelitian ini bertujuan untuk mengetahui tingkat kelayakan media pembelajaran buletin dalam bentuk buku saku pada materi Termokimia di kelas XI SMA Swasta Iskandar Muda terhadap tanggapan pendidik dan peserta didik. Jenis penelitian yang digunakan adalah penelitian pengembangan (R&D) tipe Borg and Gall dengan pendekatan kualitatif. Jenis Borg and Gall yang dilakukan pada penelitian ini adalah 6 tahap, yaitu (1) potensi dan masalah, (2) pengumpulan data, (3) desain produk, (4) validasi desain, (5) revisi desain, dan (6) uji coba produk. Pengumpulan data dilakukan di SMA Swasta Iskandar Muda dengan sampel yang diambil 2 orang pendidik kimia dan 31 orang peserta didik yang dipilih secara purposive sampling. Kelayakan media buletin dalam bentuk buku saku dinilai oleh 4 orang validator yaitu 2 validator materi diperoleh persentase rata-rata 75,8% dan 2 validator media (desain) diperoleh presentase rata-rata sebesar 84,0%. Persentase tanggapan pendidik diperoleh rata-rata 70,47% dan peserta didik diperoleh 86,2%. Berdasarkan hasil penelitian yang didapat bahwa media buletin dalam bentuk buku saku yang telah dikembangkan layak digunakan dalam proses pembelajaran materi Termokimia. Peneliti menyarankan kedepannya dapat menggunakan buletin dalam bentuk buku saku bervariasi pada materi kimia lainnya.
Kata Kunci: Buku Saku, Buletin, Media, Termokimia.
The research that has purpose to determine the feasibility of learning media in the form of a pocket booklet on thermochemical material in class XI Iskandar Muda Private High School on the responses of educators and students. This type of research is a Borg and Gall type research and development (R&D) with a qualitative approach. The Borg and Gall types conducted in this study are 6 stages, namely (1) potential and problems, (2) data collection, (3) product design, (4) design validation, (5) design revision, and (6) trial product. Data collection was carried out at Iskandar Muda Private High School with a sample taken by 2 chemical educators and 31 students. The feasibility of the bulletin media in the form of a pocket book was assessed by 4 validators namely 2 material validators obtained an average percentage of 75.8% and 2 media validators (designs) obtained an average percentage of 84.0%. Percentage of educator responses obtained an average percentage of 70.47% and students gained 86,2%. Based on the research results obtained that the bulletin media in the form of pocket books that have been developed are suitable for use in the learning process of Thermochemical material. Researchers suggest that in the future you can use bulletins in the form of varied pocket books on other chemical materials.
Keywords: Bulletin, Media, Pocket Book, Thermochemistry.
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Salman, Erick, and Helvi Darsi. "Pengembangan Aktivitas Gerak Berbasis Modifikasi Permainan untuk Meningkatkan Kemampuan Keterampilan Motorik pada Anak Sekolah Dasar." Gelanggang Olahraga: Jurnal Pendidikan Jasmani dan Olahraga (JPJO) 4, no. 1 (December 24, 2020): 47–60. http://dx.doi.org/10.31539/jpjo.v4i1.1203.
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This study aims to produce a motor learning module through game modification in elementary school children and can be used by sports and health physical education teachers (PJOK) in learning. This research is a development research (education research and development (R & D) with the Dick and Carey model approach. There are 7 steps of the Dick and Carey model, namely: (1) development of information in the field; (2) analysis information; (3) developing the initial product (draft module); (4) expert validation and revision; (5) small-scale field trials and revisions; (6) large-scale field trials and revisions; and (7) making the final product. used in this development research, namely: (1) interviews; (2) teacher observations; and (3) questionnaires. Data analysis techniques used qualitative and quantitative descriptive analysis. The results showed that: (1) validation results obtained from Expert experts obtained 80.1% (2) small-scale trials on 12 grade III students at SD Negeri 51 Lebong obtained 75.3%; (3) large-scale product trials on 40 grade III and IV students at SD Negeri 32 Lebong obtained 78 , 5%; (3) m the developed toothpaste is categorized as good in improving children's motor skills. In conclusion, the motion activity module through game modification can improve motor skills in elementary school children and is feasible to be applied to learning.
Keywords: Movement Activities, Motor Skills, Game Modification
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Blome, Christine, Natalia Kirsten, Ibrahim Nergiz, Ulrich Schiffner, Marina Otten, and Matthias Augustin. "New method of measuring subjective well-being: prospective validation study of the ‘Daily Experience Sampling Questionnaire’ (DESQ) in patients with psoriasis and healthy subjects in Germany." BMJ Open 10, no. 12 (December 2020): e039227. http://dx.doi.org/10.1136/bmjopen-2020-039227.
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ObjectivesTo validate the newly developed Daily Experience Sampling Questionnaire (DESQ) that measures affective subjective well-being (SWB). The DESQ is an end-of-day diary in which respondents retrospectively rate their SWB at six different, randomly determined moments; it is completed over 1 week. The DESQ shall provide an alternative or complementary approach to existing methods of near-time SWB measurement (experience sampling, Day Reconstruction Method). The primary research objective was to determine criterion validity of the DESQ.DesignProspective, non-interventional study.SettingParticipants were recruited in Hamburg, Germany, at a specialised outpatient clinic (patients) and via different channels (healthy participants).Participants101 adults with diagnosed and stable psoriasis (46 women, 55 men); 105 adults without psoriasis (49 women, 56 men).Primary and secondary outcome measuresParticipants completed the DESQ for 3 weeks. In weeks 2 and 3, they also performed experience sampling. Criterion validity was determined by weekwise intraclass correlations (ICC) between both methods. Sensitivity to change was determined by the correlation between changes in both methods from weeks 2 to 3. For convergent validity, related concepts such as life satisfaction were measured. Retest reliability was determined using DESQ values of weeks 2 and 3.ResultsCriterion validity was excellent (ICC: patients=0.86, 95% CI 0.81 to 0.91; healthy participants=0.86, 95% CI 0.79 to 0.91). Sensitivity to change was r=0.57 and r=0.56, respectively. Correlations with convergent criteria were mostly significant and higher in constructs more proximal to SWB. The ICC indicating retest reliability was 0.77 in patients (95% CI 0.68 to 0.84) and 0.81 in healthy participants (95% CI 0.73 to 0.86).ConclusionsThe DESQ is a valid, reliable and feasible instrument for SWB measurement in people with psoriasis and healthy people. Its approach of end-of-day evaluations of single moments may also lend itself to the measurement of other highly time-variant constructs such as pain, fatigue or depression.
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Bourgne, Céline, Marc Berger, and Alexander Kurze. "Clinical validation of NGS workflow in myeloid neoplasms." Journal of Clinical Oncology 37, no. 15_suppl (May 20, 2019): e18557-e18557. http://dx.doi.org/10.1200/jco.2019.37.15_suppl.e18557.
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e18557 Background: The advent of NGS technologies revolutionized patient management. Compiling a comprehensive list of genomic alterations and summarizing the clinical implications is complex and time-consuming. One main difficulty lies in detecting relevant genomic alterations with actionable, diagnostic and prognostic value. The development of bioinformatic tools is essential to interpret genomic data. Here we describe the validation of an end-to-end genomic NGS workflow to diagnose myeloid disorders. Methods: Performed on 81 patients previously diagnosed using non-NGS diagnostic tests, this study aims at finding out if an NGS diagnostic approach can accelerate the diagnosis process. DNA was extracted from purified mononuclear cells (n = 54), polymorphonuclear cells (n = 50) and/or total leucocytes (n = 58) from peripheral blood and bone marrow (n = 9). Genomic analysis was performed using a capture-based solution (MYS by SOPHiA GENETICS) covering 30 relevant genes associated with MDS, MPN and Leukemia. Sequencing was performed on Illumina MiSeq and results were analyzed using the SOPHiA platform. Results: We performed 2 validation runs with high raw reads quality (Phred-score > 35). Over 90% of reads were on-target and coverage was larger > 1000x with a mean of 10 regions falling below this threshold for each sample. Repeatability and reproducibility were evaluated with 6 samples and showed a good correlation between intra (R = 0.993) and inter run (R = 0.97) replicates. Average number of driver mutation was 1.3 for patients with MPN (n = 38), 3 for patients with CMML (n = 9), 2.3 for patients with MDS (n = 10), 2.5 for patients with AML (n = 13) and 1.2 for other neoplasms (n = 11). Obtained NGS results supported previous diagnoses. However for patients where peripheral blood and bone marrow samples were used to perform the analysis, one patient with mastocytosis has a discrepancy of variants found in each sample type. We detected 4 variants in peripheral blood and one additional variant in DNA extracted from bone marrow. The mutation occurred in the RUNX1 gene and was associated to an unfavourable prognosis with higher risk of relapse. Conclusions: We described here the successful validation of a single NGS panel to diagnose multiple myeloid neoplasms. The workflow shows excellent reliability in terms of reproducibility and repeatability which is essential for clinical implementation. Each method has its own benefits and limitations and interpretation of results should be made taking into account the type of the sample used.
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SUPRAPTO, SUPRAPTO. "MODEL PEMBELAJARAN KOOPERATIF MELALUI PENDEKATAN NOKEN PADA MATERI KESEIMBANGAN LINGKUNGAN SEBAGAI UPAYA PENINGKATAN AKTIVITAS DAN HASIL BELAJAR BIOLOGI KELAS X SISWA SMA NEGERI 3 JAYAPURA." Jurnal Ilmu Pendidikan Indonesia 5, no. 2 (May 22, 2018): 9–18. http://dx.doi.org/10.31957/jipi.v5i2.244.
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This research is a development of learning model (R & D) with ADDIE approach, expected to overcome the problem of classroom learning. This research produces the following: 1) development stage in the form of: analysis, design, develompent, implementation, and evaluation of the field, 2) NOKEN approach expressed very valid by validator, 3) The effectiveness of biology learning through NOKEN approach is very good, more than 80% student activity and more than 20% grade test completion, 4) NOKEN learning approach has a response rate of over 90%, with an indication of interest to students. Based on the results obtained, NOKEN learning approach, can be used as one of the alternative pendektan new learning as an effort to improve the quality of learning in class, especially class X biology subjects Environmental balance material
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Imanda, Riska, Ayu Rahmi, Sri Setiawaty, Ayu Daun Dandina, and Nadia Humaira. "Development of Chemistry Textbooks Based Scientific Approach in Efforts to Implement Prototype Curriculum at Schools." Jurnal Penelitian Pendidikan IPA 8, no. 6 (December 30, 2022): 3153–58. http://dx.doi.org/10.29303/jppipa.v8i6.2317.
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The purpose of research is to develop the chemistry textbook based on the scientific approach in implementing the prototype curriculum in schools. The development of textbooks uses the type of R & D. The R & D model used is ADDIE model which has five Phases, namely (1) analysis, (2) design, (3) development, (4) implementation, and (5) (evaluation). At the analysis is carried out with initial analysis, participant analysis students, task analysis, concept analysis, and formulating learning objectives. At Phase design is carried out preparation of core competency (KI) and basic competencies (KD), preparation of the grid/framework module, and the initial draft of the module. The development includes the assessment Phase of the expert team on the developed textbooks. Implementation and evaluation phase includes development trials to see the effectiveness of the developed textbooks. The research subjects consisted of 9 teachers’ chemical. Data collection is carried out to determine the feasibility of products that have been developed through a validation questionnaire filled out by experts and response questionnaire teachers are also students. The results showed that the -based chemistry textbooks scientific approach developed has received a very feasible assessment by experts to be tested for its use in learning. Next, the teacher's response and students towards scientific approach the developed at the trial Phase is classified as a very feasible category to be implemented in learning. In addition, chemistry textbooks based on a scientific approach are effectively used as a textbook.
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Ulandari, Riska, Ganda Hijrah Selaras, Heffi Alberida, and Relsas Yogica. "Validitas Penuntun Praktikum Biologi Berbasis Pendekatan Saintifik untuk Kelas XI SMA Semester I." FONDATIA 6, no. 4 (December 1, 2022): 807–16. http://dx.doi.org/10.36088/fondatia.v6i4.2162.
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Giving hands-on experience is very important in learning biology. One of the ways to provide direct experience is through practicum activities, so that the method used to guide and direct students in practical activities is by using a biology practicum guide. Based on the observations that have been made, it is known that the practicum guide used is still very simple, has not applied aspects of a scientific approach that are in accordance with the demands of the 2013 curriculum. This type of research is development research (R&D) which aims to produce a scientific approach-based biology practicum guide for class XI SMA semester I valid. This study uses a four-D development model. Based on the validation that has been done, the results obtained an average value of 85.56% with very valid criteria. So, it can be concluded that the biological guide based on the scientific approach that has been developed is valid and suitable to be used as a guide in practical activities. Practical activities play an important role in learning biology. One component that helps the process of practicum activities is a practicum guide. Based on the observations that have been made, it is known that the practicum guide used is still very simple, has not applied aspects of a scientific approach that are in accordance with the demands of the 2013 curriculum. This type of research is development research (R&D) using 3 stages of the 4-D development model (four -D models). The practicum guide developed was validated by two biology lecturers and one biology subject teacher. The instrument used in this study was a validity test questionnaire. The data analysis technique used is quantitative and qualitative descriptive analysis. Based on the validation that has been done, the results obtained an average value of 85.56% with very valid criteria. So, it can be concluded that the biological guide based on the scientific approach developed is valid and suitable to be used as a guide in practical activities.
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Otuoze, Suleiman Hassan, Dexter V. L. Hunt, and Ian Jefferson. "Neural Network Approach to Modelling Transport System Resilience for Major Cities: Case Studies of Lagos and Kano (Nigeria)." Sustainability 13, no. 3 (January 28, 2021): 1371. http://dx.doi.org/10.3390/su13031371.
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Congestion has become part of everyday urban life, and resilience is very crucial to traffic vulnerability and sustainable urban mobility. This research employed a neural network as an adaptive artificially-intelligent application to study the complex domains of traffic vulnerability and the resilience of the transport system in Nigerian cities (Kano and Lagos). The input criteria to train and check the models for the neural resilience network are the demographic variables, the geospatial data, traffic parameters, and infrastructure inventories. The training targets were set as congestion elements (traffic volume, saturation degree and congestion indices), which are in line with the relevant design standards obtained from the literature. A multi-layer feed-forward and back-propagation model involving input–output and curve fitting (nftool) in the MATLAB R2019b software wizard was used. Three algorithms—including Levenberg–Marquardt (LM), Bayesian Regularization (BR), and a Scaled Conjugate Gradient (SCG)—were selected for the simulation. LM converged easily with the Mean Squared Error (MSE) (2.675 × 10−3) and regression coefficient (R) (1.0) for the city of Lagos. Furthermore, the LM algorithm provided a better fit for the model training and for the overall validation of the Kano network analysis with MSE (4.424 × 10−1) and R (1.0). The model offers a modern method for the simulation of urban traffic and discrete congestion prediction.
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Maulidah Rahmah, Sylvia, and Joni Susilowibowo. "Pengembangan bahan ajar berupa e-book pada mata pelajaran akuntansi keuangan kompetensi dasar akuntansi piutang kelas XI berbasis pendekatan saintifik di SMK Yapalis Krian." Jurnal Riset Pendidikan Ekonomi 6, no. 2 (October 30, 2021): 60–70. http://dx.doi.org/10.21067/jrpe.v6i2.5727.
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This research aims to develop e-book teaching materials, analyze the feasibility level of e-books and analyze student responses to e-books. The subjects in this study are financial accounting on the basic competence of accounts receivable accounting. Teaching materials in the form of e-books were developed according to the implementation of the 2013 curriculum based on a scientific approach. The research method used is Research and Development (R&D) with a 4-D model. The validators in the study were 3 lecturers according to the intended field and one teacher who was an expert in financial accounting subjects. The assessment data distributed to the validator comes from the review sheet and then the validation sheet. A total of 20 students of class XI Financial and Institutional Accounting at SMK Yapalis Krian were also one of the respondents. This is to determine the feasibility of teaching materials so that they are suitable for use in the learning process. The product developed produces a very feasible interpretation with an average feasibility recapitulation of 89.49%. From these results, there are several components listed with very feasible interpretations, namely the feasibility of the material 89.89%, the feasibility of language 86.67% and the feasibility of graphics 91.93%. For the average results, students stated that the interpretation was very well understood with a percentage of 88.12%. So this teaching material is suitable for use in the learning process
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Ulfaini, Riyana, and Dian Permatasari. "Integrating Contextual Approach and Islamic Values in Three-Variable Linear Equations System Module." Jurnal Tadris Matematika 5, no. 1 (June 27, 2022): 1–16. http://dx.doi.org/10.21274/jtm.2022.5.1.1-16.
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In the 2013 Curriculum, students are expected to have knowledge and skills in lessons and also have spiritual and social attitudes. Therefore, it is necessary to connect learning material with real-life and religious aspects. This research aims to develop a mathematical module based on a contextual approach that integrates Islamic values ​​into a valid Three-variable Linear Equations System. This research is a research and development (R&D). This research was designed by following Richey and Klein's development steps, namely the PPE model. The PPE model consists of 3 steps: planning, production, and evaluation. The data collection instruments used in this study were a material expert validity assessment sheet and a media expert validity assessment sheet. The data that has been obtained were analyzed using average and percentage calculations and classifying the results based on predetermined criteria. The results showed that the mathematics module based on a contextual approach that integrated Islamic values ​​in the material of a Three-variable Linear Equations System met the valid criteria based on the assessment of expert validators. This shows that the module have "good" qualification with an average score of 83.40% by the material expert validator and "good" qualification with an average score of 87.5% by the media expert validator.
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Walter, Joan E., Ursina Honegger, Christian Puelacher, Deborah Mueller, Max Wagener, Nicolas Schaerli, Ivo Strebel, et al. "Prospective Validation of a Biomarker-Based Rule Out Strategy for Functionally Relevant Coronary Artery Disease." Clinical Chemistry 64, no. 2 (February 1, 2018): 386–95. http://dx.doi.org/10.1373/clinchem.2017.277210.
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Abstract BACKGROUND This study aimed to prospectively advance a rule-out strategy for functionally significant coronary artery disease (CAD) by use of high-sensitivity cardiac troponin I (hs-cTnI) from bench to bedside, by application of a 3-step approach: validation in serum, correlation in plasma, and application on a clinical platform. METHODS Patients without known CAD referred for rest/stress myocardial perfusion single-photon emission tomography/computer tomography (MPI-SPECT/CT) were assigned to 3 consecutive cohorts: validation, correlation, and application. Functionally relevant CAD was adjudicated with the use of expert interpretation of MPI-SPECT/CT and, if available, coronary angiography. In the validation cohort resting hs-cTnI was measured in serum before stress testing with the research Erenna system, in serum and plasma in the correlation cohort with the research Erenna system, and in plasma in the application cohort with the clinical Clarity system. RESULTS Overall, functionally relevant CAD was adjudicated in 21% (304/1478) of patients. In the validation cohort (n = 613), hs-cTnI concentrations were significantly higher in patients with functionally relevant CAD (median 2.8 ng/L vs 1.9 ng/L, P < 0.001) as compared to patients without functionally relevant CAD and allowed a rule out with 95% sensitivity in 14% of patients. In the correlation cohort (n = 606), hs-cTnI concentrations in serum and plasma strongly correlated (Spearman r = 0.921) and had similar diagnostic accuracy as quantified by the area under the receiver operating characteristic curve (0.686 vs 0.678, P = 0.425). In the application cohort (n = 555), very low hs-cTnI plasma concentrations (< 0.5 ng/L) ruled out functionally relevant CAD with 95% sensitivity in 10% of patients. CONCLUSIONS A single resting plasma hs-cTnI measurement can safely rule out functionally relevant CAD in around 10% of patients without known CAD.
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Newman, Aaron M., Aki Nakao, Kathy Li, Douglas Collins Wilson, Chih-Long Liu, Maximilian Diehn, and Ash A. Alizadeh. "Analytical validation of iSort digital cytometry for leukocyte enumeration in clinical tumor specimens." Journal of Clinical Oncology 38, no. 15_suppl (May 20, 2020): e15243-e15243. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.e15243.
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e15243 Background: Tumor infiltrating leukocytes (TILs) are major determinants of anti-tumor immune responses and mediate effector functions for diverse immunotherapies. Techniques relying on intact cells such as flow cytometry (FACS), immunohistochemistry (IHC), and scRNA-Seq can be powerful for measuring TIL heterogeneity. However, such methods are often impractical on large patient cohorts, can be poorly quantitative, and some cannot be applied to formalin-fixed paraffin embedded (FFPE) specimens. We developed iSort, a transcriptome deconvolution method based on CIBERSORTx for TIL enumeration. We evaluated iSort by comparing its performance in FFPE and fresh frozen (FF) human tumor tissues to established methods. Methods: We profiled human tumors for diverse TIL subsets, as quantified by iSort, FACS, and IHC. iSort was performed on RNA-Seq libraries derived from bulk human tumors, including FF tumor tissue samples, tumor cell suspensions obtained after dissociation, and FFPE specimens. We assessed the influence of tissue fixation on common TIL subsets enumerated by iSort, by comparing matched pairs of FF and FFPE lung tumor specimens (NSCLC). Finally, we compared iSort with automated microscopic enumeration of CD8 TILs by IHC on primary human lung tumors (FFPE/NSCLC). Results: iSort TIL enumeration was highly correlated with FACS across primary human tumors (CRC = 3, HNSCC = 1) for common TIL subsets (B cells, CD8 T, CD4 T, monocytes/macrophages, dendritic cells, PMNs/MDSCs) and total immune content (median r = 0.91 [0.71 - 0.99]). Tissue dissociation caused significant depletion of monocytes/macrophages (p < 0.01), when comparing bulk tumor specimens with cell suspensions after sample digestion. iSort showed high correlation across 12 TIL subsets when comparing 9 pairs of FF and FFPE specimens (r = 0.90). Finally, we observed high linearity between iSort and microscopic enumeration of CD8 TILs from IHC (r = 0.87, n = 5). Conclusions: iSort digital cytometry achieves accurate and robust TIL enumeration as compared with FACS and IHC, showing comparable performance in fixed and frozen primary human tumors. Importantly, iSort is directly applicable to bulk tumors and is unaffected by tissue dissociation artifacts, unlike methods requiring cell suspensions for TIL enumeration (FACS, scRNA-seq). Therefore, iSort is a promising approach for development and measurement of immunotherapy biomarkers.
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Syukri, Muhammad, Dewi Agusti Yanti, Elmi Mahzum, and Abdul Hamid. "Development of a PjBL Model Learning Program Plan based on a STEM Approach to Improve Students' Science Process Skills." Jurnal Penelitian Pendidikan IPA 7, no. 2 (April 21, 2021): 269. http://dx.doi.org/10.29303/jppipa.v7i2.680.
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The purpose of the research is to developing Learning Program Plan (LPP) with a PjBL model based on the STEM approach to improve the students’ science process skills in physics learning. This research refers to the development of ADDIE, namely: 1) Analysis, 2) Design, 3) Development, 4) Implementation and 5) Evaluation. The worthiness of the Learning Program Plan is measure by the result of the Learning Program Plan validation and the responding of the subject is 7 teachers. The result of all the Learning Program Plan showing average value is 4, that is the valid category. The research design used in the study is Research and Developing (R&D). The research subject is 3 physics teachers at SMA Negeri 5 Banda Aceh, 1 physics teacher at SMA Negeri 1 Lawe Alas, 1 physics teacher at MA Negeri 1 Aceh Tenggara, and 2 physics teachers at SMA 3 Kutacane. Data of the research are questionnaires that are given to the teacher. Data management is carried out by Statistik analysis Likert scale. Questionnaire of the result showed until 89%. From both measures are found the development of Learning Program Plan model PjBL that teacher assessment result to Learning Program Plan with an average score 4.45 with the overall percentage based STEM approach to improving science process student skills in physics learning.
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Fan, Yongzhen, Simone Fezzi, Pengcheng Sun, Nan Ding, Xiaohui Li, Xiaorong Hu, Shuang Wang, William Wijns, Zhibing Lu, and Shengxian Tu. "In Vivo Validation of a Novel Computational Approach to Assess Microcirculatory Resistance Based on a Single Angiographic View." Journal of Personalized Medicine 12, no. 11 (October 31, 2022): 1798. http://dx.doi.org/10.3390/jpm12111798.
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(1) Background: In spite of the undeniable clinical value of the index of microvascular resistance (IMR) in assessing the status of coronary microcirculation, its use globally remains very low. The aim of this study was to validate the novel single-view, pressure-wire- and adenosine-free angiographic microvascular resistance (AMR) index, having the invasive wire-based IMR as a reference standard. (2) Methods: one hundred and sixty-three patients (257 vessels) were investigated with pressure wire-based IMR. Microvascular dysfunction (CMD) was defined by IMR ≥ 25. AMR was independently computed from the diagnostic coronary angiography in a blinded fashion. (3) Results: AMR demonstrated a good correlation (r = 0.83, p < 0.001) and diagnostic performance (AUC 0.94; 95% CI: 0.91 to 0.97) compared with wire-based IMR. The best cutoff value for AMR in determining IMR ≥ 25 was 2.5 mmHg*s/cm. The overall diagnostic accuracy of AMR was 87.2% (95% CI: 83.0% to 91.3%), with a sensitivity of 93.5% (95% CI: 87.0% to 97.3%), a specificity of 82.7% (95% CI: 75.6% to 88.4%), a positive predictive value of 79.4% (95% CI: 71.2% to 86.1%) and a negative predictive value of 94.7% (95% CI: 89.3% to 97.8%). No difference in terms of CMD rate was described among different clinical presentations. (4) Conclusions: AMR derived solely from a single angiographic view is a feasible computational alternative to pressure wire-based IMR, with good diagnostic accuracy in assessing CMD.
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Garcia-Rudolph, Alejandro, Alberto Garcia-Molina, Eloy Opisso, and Jose Tormos Muñoz. "Personalized Web-Based Cognitive Rehabilitation Treatments for Patients with Traumatic Brain Injury: Cluster Analysis." JMIR Medical Informatics 8, no. 10 (October 6, 2020): e16077. http://dx.doi.org/10.2196/16077.
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Background Traumatic brain injury (TBI) is a leading cause of disability worldwide. TBI is a highly heterogeneous disease, which makes it complex for effective therapeutic interventions. Cluster analysis has been extensively applied in previous research studies to identify homogeneous subgroups based on performance in neuropsychological baseline tests. Nevertheless, most analyzed samples are rarely larger than a size of 100, and different cluster analysis approaches and cluster validity indices have been scarcely compared or applied in web-based rehabilitation treatments. Objective The aims of our study were as follows: (1) to apply state-of-the-art cluster validity indices to different cluster strategies: hierarchical, partitional, and model-based, (2) to apply combined strategies of dimensionality reduction by using principal component analysis and random forests and perform stability assessment of the final profiles, (3) to characterize the identified profiles by using demographic and clinically relevant variables, and (4) to study the external validity of the obtained clusters by considering 3 relevant aspects of TBI rehabilitation: Glasgow Coma Scale, functional independence measure, and execution of web-based cognitive tasks. Methods This study was performed from August 2008 to July 2019. Different cluster strategies were executed with Mclust, factoextra, and cluster R packages. For combined strategies, we used the FactoMineR and random forest R packages. Stability analysis was performed with the fpc R package. Between-group comparisons for external validation were performed using 2-tailed t test, chi-square test, or Mann-Whitney U test, as appropriate. Results We analyzed 574 adult patients with TBI (mostly severe) who were undergoing web-based rehabilitation. We identified and characterized 3 clusters with strong internal validation: (1) moderate attentional impairment and moderate dysexecutive syndrome with mild memory impairment and normal spatiotemporal perception, with almost 66% (111/170) of the patients being highly educated (P<.05); (2) severe dysexecutive syndrome with severe attentional and memory impairments and normal spatiotemporal perception, with 49.2% (153/311) of the patients being highly educated (P<.05); (3) very severe cognitive impairment, with 45.2% (42/93) of the patients being highly educated (P<.05). We externally validated them with severity of injury (P=.006) and functional independence assessments: cognitive (P<.001), motor (P<.001), and total (P<.001). We mapped 151,763 web-based cognitive rehabilitation tasks during the whole period to the 3 obtained clusters (P<.001) and confirmed the identified patterns. Stability analysis indicated that clusters 1 and 2 were respectively rated as 0.60 and 0.75; therefore, they were measuring a pattern and cluster 3 was rated as highly stable. Conclusions Cluster analysis in web-based cognitive rehabilitation treatments enables the identification and characterization of strong response patterns to neuropsychological tests, external validation of the obtained clusters, tailoring of cognitive web-based tasks executed in the web platform to the identified profiles, thereby providing clinicians a tool for treatment personalization, and the extension of a similar approach to other medical conditions.