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Journal articles on the topic 'Quantitative CEUS'

Author: Grafiati

Published: 9 March 2023

Last updated: 31 July 2025

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1

Liang, Xing-xin, Fan Li, Feng Gao, et al. "The Value of the Model and Quantitative Parameters of Contrast-Enhanced Ultrasound in Judging the Severity of SHPT." BioMed Research International 2016 (2016): 1–5. http://dx.doi.org/10.1155/2016/6064526.

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Using the model and quantitative parameters of contrast-enhanced ultrasound (CEUS) to assess the severity of secondary hyperparathyroidism (SHPT) was proposed. 42 SHPT patients who underwent CEUS examination were divided into three groups, light, moderate, and heavy as per parathyroid hormone (PTH). The process of CEUS was divided into two phases, wash-in phase and wash-out phase. The three groups were analyzed with their enhancing model in the two phases. The quantitative parameters of CEUS such as Arrival Time (AT), Time to Peak (TTP), Mean Transit Time (MTT), and Maximum Intensity (IMAX) we

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Vavuranakis, Manolis, Fragiska Sigala, Dimitrios A. Vrachatis, et al. "Quantitative analysis of carotid plaque vasa vasorum by CEUS and correlation with histology after endarterectomy." Vasa 42, no. 3 (2013): 184–95. http://dx.doi.org/10.1024/0301-1526/a000267.

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Background: Intraplaque neovascularization and vasa vasorum (VV) proliferation contribute in the progression and rupture of atherosclerotic lesions. Contrast Enhanced Ultrasonography (CEUS) has been reported to attain data regarding intraplaque neovessels and VV. However, whether the detection of microbubbles by CEUS within atherosclerotic plaques truly represents microvessels is a point of concern. We aimed to evaluate stable and unstable carotid artery plaque (CAP) VV pattern by CEUS and its correlation with histology and immunochemistry. Patients and methods: Patients with CAP scheduled for

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Pavlovics, Sergejs, Maija Radzina, Rita Niciporuka, et al. "Contrast-Enhanced Ultrasound Qualitative and Quantitative Characteristics of Parathyroid Gland Lesions." Medicina 58, no. 1 (2021): 2. http://dx.doi.org/10.3390/medicina58010002.

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Background and Objectives: preoperative differentiation of enlarged parathyroid glands may be challenging in conventional B-mode ultrasound. The aim of our study was to analyse qualitative and quantitative characteristics of parathyroid gland lesions, using multiparametric ultrasound protocol—B-mode, Colour Doppler (CD), and contrast-enhanced ultrasound (CEUS)—and to evaluate correlation with morphology in patients with hyperparathyroidism (HPT). Materials and Methods: consecutive 75 patients with 88 parathyroid lesions and biochemically confirmed HPT prior to parathyroidectomy were enrolled i

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Hu, Zhipeng, Rong Xue, Zhixi Liu, Liang Liu, and Zheli Gong. "Role of contrast-enhanced ultrasound with time-intensity curve analysis about thyroid nodule and parenchyma for differentiating BRAF V600E mutation status." PeerJ 13 (February 25, 2025): e19006. https://doi.org/10.7717/peerj.19006.

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Background The BRAF V600E mutation was proven associated with papillary thyroid cancer (PTC) which has more aggressive behavior and could affect the outcome of PTC. The objective of this study was to observe more contrast-enhanced ultrasound (CEUS) time-intensity curve (TIC)—based quantitative parameters in nodules and surrounding parenchyma and analyze the association between the TIC-based quantitative parameters and BRAF V600E mutation status in patients with PTC. Methods A retrospective analysis of 447 PTC patients was conducted. Prior to thyroidectomy or fine needle aspiration (FNA), all p

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Han, Dan, Ting Wang, Ruiqi Wang, Jingyu Chen, and Yi Tang. "Application of Quantitative Parameters of Contrast-Enhanced Ultrasound in Common Benign and Malignant Lesions in Pediatric Livers: A Preliminary Study." Diagnostics 13, no. 22 (2023): 3443. http://dx.doi.org/10.3390/diagnostics13223443.

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We aimed to investigate the diagnostic utility of quantitative parameters of contrast-enhanced ultrasound (CEUS) for benign and malignant liver lesions in pediatric patients. This was a single-center retrospective analysis of children with liver lesions who underwent CEUS at our hospital between July 2019 and February 2023. The CEUS perfusion patterns for all lesions were qualitatively analyzed using histopathology, contrast-enhanced magnetic resonance imaging, contrast-enhanced computed tomography, or long-term clinical follow-up as reference standards. The CEUS images were quantitatively ana

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Lu, Qin, Huihui Sun, Qian Yu, and Dongdong Tang. "Analysis of Contrast-Enhanced Ultrasound and Elastography in the Diagnosis of Benign and Malignant Apocrine Breast Tumors." Journal of Medical Imaging and Health Informatics 11, no. 7 (2021): 1807–16. http://dx.doi.org/10.1166/jmihi.2021.3531.

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In the past thirty years, breast cancer in women has continued to rise. The age of onset for women has become lower. Contrast-enhanced ultrasound (CEUS) can clearly show the blood perfusion and neovascularization of breast masses. Elastography provides information on the stiffness of tissues. The combination of them shows a good advantage in the various early diagnosis of breast cancer. The combined electrograph can distinguish benign and malignant apocrine breast tumors. The shear wave electrograph (SWE) combined with CEUS has the strongest consistency in the diagnosis and pathology of breast

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Goertz, Ruediger S., Daniel Klett, Dane Wildner, Raja Atreya, Markus F. Neurath, and Deike Strobel. "Quantitative contrast-enhanced ultrasound for monitoring vedolizumab therapy in inflammatory bowel disease patients: a pilot study." Acta Radiologica 59, no. 10 (2018): 1149–56. http://dx.doi.org/10.1177/0284185117752032.

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Background Microvascularization of the bowel wall can be visualized and quantified non-invasively by software-assisted analysis of derived time-intensity curves. Purpose To perform software-based quantification of bowel wall perfusion using quantitative contrast-enhanced ultrasound (CEUS) according to clinical response in patients with inflammatory bowel disease treated with vedolizumab. Material and Methods In a prospective study, in 18 out of 34 patients, high-frequency ultrasound of bowel wall thickness using color Doppler flow combined with CEUS was performed at baseline and after 14 weeks

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Kaltenbach, T. E. M., T. Graeter, R. A. Mason, et al. "Determination of vitality of liver lesions by alveolar echinococcosis." Nuklearmedizin 54, no. 01 (2015): 43–49. http://dx.doi.org/10.3413/nukmed-0670-14-05.

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SummaryObjective of our study is qualitative and quantitative comparison of contrast enhanced ultrasound (CEUS) and 18F-FDG PETCT in monitoring hepatic alveolar echinococcosis (HAE). Parasitic liver lesions were examined regarding number, size, morphology, vascularization and metabolic activity. Patients, methods: 36 patients with medicallytreated HAE were included in this prospective clinical study. Abdominal ultrasound and CEUS were carried out using ultrasound contrast amplifier SonoVue®. As part of monitoring, patients were examined by 18F-FDG-PET-CT. Quantitative analysis of CEUS was perf

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Wakonig, Katharina Margherita, Markus Herbert Lerchbaumer, Steffen Dommerich, et al. "Assessment of Parotid Gland Tumors by Means of Quantitative Multiparametric Ultrasound (mpUS)." Diagnostics 13, no. 1 (2022): 12. http://dx.doi.org/10.3390/diagnostics13010012.

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Objective: The preoperative diagnostical differentiation of parotid gland tumor (PGT) is not always simple due to several different entities. B-mode-ultrasound (US) remains the imaging modality of choice, while histopathology serves as the gold standard for finalizing the diagnosis. We aimed to evaluate the use of multiparametric US (mpUS) in the assessment of PGT. Methods: We included 97 PGTs from 96 patients. A standardized mpUS protocol using B-mode-US, shear-wave elastography (SWE), and standardized contrast-enhanced ultrasound (CEUS) was performed prior to surgical intervention. SWE was a

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Wang, Ling, and Chandra Mohan. "Contrast-enhanced ultrasound: A promising method for renal microvascular perfusion evaluation." Journal of Translational Internal Medicine 4, no. 3 (2016): 104–8. http://dx.doi.org/10.1515/jtim-2016-0033.

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Abstract This article reviews the application of contrast-enhanced ultrasound (CEUS) in gauging renal microvascular perfusion in diverse renal diseases. The unique nature of the contrast agents used in CEUS provides real-time and quantitative imaging of the vasculature. In addition to the traditional use of CEUS for evaluation of kidney masses, it also emerges as a safe and effective imaging approach to assess microvascular perfusion in diffuse renal lesions, non-invasively. Although the precise CEUS parameters that may best predict disease still warrant systematic evaluation, animal models an

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Banzato, Tommaso, Silvia Burti, Giuseppe Rubini, et al. "Contrast-enhanced ultrasonography features of hepatobiliary neoplasms in cats." Veterinary Record 186, no. 10 (2019): 320. http://dx.doi.org/10.1136/vr.105453.

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BackgroundContrast-enhanced ultrasonography (CEUS) features of primary hepatobiliary neoplasms have been reported in dogs but no information is available in cats.MethodsQualitative and quantitative features of bile duct adenomas (BDAs, n=20), bile duct carcinomas (BDCs, n=16), and hepatocellular carcinomas (HCCs, n=8) are described in 44 cats.ResultsThere was an overlap in CEUS qualitative features between different histotypes, both in wash-in and wash-out phases. Distinction between different neoplasms based only on the CEUS qualitative features was not possible. At peak of enhancement, the B

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Wang, Lan, Ming Li, Tiantian Dong, Yuanyuan Li, Ci Yin, and Fang Nie. "Pancreatic Ductal Adenocarcinoma: The Characteristics of Contrast-Enhanced Ultrasound Are Correlated with the Hypoxic Microenvironment." Diagnostics 13, no. 20 (2023): 3270. http://dx.doi.org/10.3390/diagnostics13203270.

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A hypoxic microenvironment is associated with an increased risk of metastasis, treatment resistance and poor prognosis of pancreatic ductal adenocarcinoma (PDAC). This study aimed to identify contrast-enhanced ultrasound (CEUS) characteristics that could predict the hypoxic microenvironment of PDAC. A total of 102 patients with surgically resected PDAC who underwent CEUS were included. CEUS qualitative and quantitative characteristics were analyzed. The expression of hypoxia-inducible factor-1α (HIF-1) and glucose transporter-1 (GLUT1) were demonstrated by immunohistochemistry. The association

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Sun, Jun, Fengyu Na, Bo Ma, Li Wang, Hanbing Shi, and Yan Ding. "Quantitative Parameters of Contrast-Enhanced Ultrasound Combined with Lung Biopsy Were Used to Evaluate the Benign and Malignant Lesions around the Lungs." Journal of Sensors 2021 (November 27, 2021): 1–14. http://dx.doi.org/10.1155/2021/2259408.

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In recent years, due to the influence of living habits and smoking, the number of lung cancer patients worldwide has increased year by year, and it has gradually developed into one of the common diseases endangering human life. CEUS can observe the lesion and realize the rapid identification of the location of the active area of the lesion. CEUS is the abbreviation of contrast-enhanced ultrasound technology. Contrast-enhanced ultrasound technology is to inject ultrasound contrast agent through a peripheral vein to perform ultrasound exploration to observe the enhancement of the internal nodule

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da Silva, Natascha, Matthias Hornung, Lukas Beyer, et al. "Intraoperative Shear Wave Elastography vs. Contrast-Enhanced Ultrasound for the Characterization and Differentiation of Focal Liver Lesions to Optimize Liver Tumor Surgery." Ultraschall in der Medizin - European Journal of Ultrasound 40, no. 02 (2018): 205–11. http://dx.doi.org/10.1055/a-0649-1000.

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Abstract Purpose Assessment of intraoperative quantitative shear wave elastography (SWE) and contrast-enhanced ultrasound (CEUS) for the characterization of focal liver lesions (FLLs) during liver surgery using postoperative histopathological results as the gold standard. Materials and Methods US data of 79 consecutive patients with 98 FLLs who underwent liver surgery between 08/2015 – 06/2017 were prospectively acquired and retrospectively analyzed. Multifrequency linear/T-shaped probes (6 – 9 MHz) were used to store cine loops of at least 5 s and images of B-mode, SWE and CEUS. The first CEU

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Hillaert, Amber, Emmelie Stock, Sophie Favril, Luc Duchateau, Jimmy H. Saunders, and Katrien Vanderperren. "Intra- and Inter-Observer Variability of Quantitative Parameters Used in Contrast-Enhanced Ultrasound of Kidneys of Healthy Cats." Animals 12, no. 24 (2022): 3557. http://dx.doi.org/10.3390/ani12243557.

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Contrast-enhanced ultrasound (CEUS) is a non-invasive imaging technique which allows qualitative and quantitative assessment of tissue perfusion. Although CEUS offers numerous advantages, a major challenge remains the variability in tissue perfusion quantification. This study aimed to assess intra- and inter-observer variability for quantification of renal perfusion. Two observers with different levels of expertise performed a quantitative analysis of 36 renal CEUS studies, twice. The CEUS data were collected from 12 healthy cats at 3 different time points with a 7-day interval. The inter- and

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Tantawi, Mohamed, Susan Shamimi-Noori, Colette M. Shaw, and John R. Eisenbrey. "State of the Art: Contrast Enhanced 4D Ultrasound to Monitor or Assess Locoregional Therapies." Digestive Disease Interventions 06, no. 01 (2022): 003–12. http://dx.doi.org/10.1055/s-0041-1741520.

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AbstractLocoregional therapies (LRTs) are an essential management tool in the treatment of primary liver cancers or metastatic liver disease. LRTs include curative and palliative modalities. Monitoring treatment response of LRTs is crucial for maximizing benefit and improving clinical outcomes. Clinical use of contrast-enhanced ultrasound (CEUS) was introduced more than two decades ago. Its portability, cost effectiveness, lack of contraindications and safety make it an ideal tool for treatment monitoring in numerous situations. Two-dimensional dynamic CEUS has been proved to be equivalent to

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Macrì, Francesco, Vito Angileri, Teresa Russo, Maria Tomiko Russo, Marco Tabbì, and Simona Di Pietro. "Evaluation of Bone Healing Using Contrast-Enhanced Ultrasonography in Non-Operative Treatment of Tibial Fracture in a Puppy Dog." Animals 11, no. 2 (2021): 284. http://dx.doi.org/10.3390/ani11020284.

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A 10-month-old mixed-breed male dog was presented with an oblique tibial fracture. The dog was treated with a Robert Jones-like bandage as a conservative approach, and was subjected to X-ray, B-mode, Color Doppler and contrast-enhanced ultrasound (CEUS) examinations during the fracture healing, in order to assess bone hemodynamic changes. B-mode, Power Doppler and CEUS examinations of the fracture gap were performed at 7, 20, 35, and 50 days post-trauma. Quantitative analysis of CEUS and perfusion parameters were obtained. On CEUS, a steep incline in signal numbers was visible in fracture gap

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Sharma, Anant, Shabnam Bhandari Grover, Chinta Mani, and Charanjeet Ahluwalia. "Contrast enhanced ultrasound quantitative parameters for assessing neoadjuvant chemotherapy response in patients with locally advanced breast cancer." British Journal of Radiology 94, no. 1121 (2021): 20201160. http://dx.doi.org/10.1259/bjr.20201160.

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Objectives: To evaluate the role of contrast-enhanced ultrasound (CEUS) quantitative parameters in predicting neoadjuvant chemotherapy (NACT) response in patients with locally advanced breast cancer (LABC). Methods: 30 patients with histologically proven LABC scheduled for NACT were recruited. CEUS was performed using a contrast bolus of 4.8 ml and time intensity curves (TICs) were obtained by contrast dynamics software. CEUS quantitative parameters assessed were peak enhancement (PE), time-to-peak (TTP), area under the curve (AUC) and mean transit time (MTT). The parameters were documented on

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Dong, Yi, Yijie Qiu, Daohui Yang, et al. "Potential application of dynamic contrast enhanced ultrasound in predicting microvascular invasion of hepatocellular carcinoma." Clinical Hemorheology and Microcirculation 77, no. 4 (2021): 461–69. http://dx.doi.org/10.3233/ch-201085.

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OBJECTIVE: To investigate the clinical value of dynamic contrast enhanced ultrasound (D-CEUS) in predicting the microvascular invasion (MVI) of hepatocellular carcinoma (HCC). PATIENTS AND METHODS: In this retrospective study, 16 patients with surgery and histopathologically proved HCC lesions were included. Patients were classified according to the presence of MVI: MVI positive group (n = 6) and MVI negative group (n = 10). Contrast enhanced ultrasound (CEUS) examinations were performed within a week before surgery. Dynamic analysis was performed by VueBox® software (Bracco, Italy). Three reg

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Cantisani, Vito, Nicola Di Leo, Emanuele David, and Dirk-André Clevert. "Role of CEUS in Vascular Pathology." Ultraschall in der Medizin - European Journal of Ultrasound 42, no. 04 (2021): 348–66. http://dx.doi.org/10.1055/a-1403-2400.

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AbstractIn recent years, the implementation of contrast-enhanced ultrasound (CEUS) in clinical practice has opened new horizons in the arterial pathologies research field, since this technique is able to supply new sets of data that can be crucial in patient management. The main applications of CEUS in the arterial system are the detection, characterization, and follow-up of carotid plaques and endoleaks after EVAR. Other situations in which CEUS was demonstrated to be a useful tool are large vessel vasculitis, dissections, and untreated aneurysms. In carotid atherosclerosis CEUS is not only a

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Haimerl, M., S. Poelsterl, L. P. Beyer, et al. "Chronic liver disease: Quantitative MRI vs CEUS-based microperfusion." Clinical Hemorheology and Microcirculation 64, no. 3 (2017): 435–46. http://dx.doi.org/10.3233/ch-168112.

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Hillaert, Amber, Emmelie Stock, Luc Duchateau, Hilde de Rooster, Nausikaa Devriendt, and Katrien Vanderperren. "B-Mode and Contrast-Enhanced Ultrasonography Aspects of Benign and Malignant Superficial Neoplasms in Dogs: A Preliminary Study." Animals 12, no. 20 (2022): 2765. http://dx.doi.org/10.3390/ani12202765.

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Contrast-enhanced ultrasonography (CEUS) is considered a promising technique for differentiation of benign and malignant tumors in humans. However, few studies have assessed superficial neoplasms in dogs by means of CEUS. The aim of this study was to identify ultrasonographic criteria evaluated by B-mode ultrasound (US) and CEUS that may be used to distinguish benign and malignant superficial neoplasms in dogs. A total of 63 superficial neoplasms from 59 dogs were evaluated using B-mode US and CEUS prior to histopathologic examination. Qualitative and quantitative parameters were compared betw

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Evdokimenko, A. N., A. O. Chechetkin, L. D. Druina, and M. M. Tanashyan. "Contrast-enhanced ultrasonography for assessing neovascularization of carotid atherosclerotic plaque." Exosomes, no. 4 (July 31, 2019): 24–31. http://dx.doi.org/10.24075/brsmu.2019.057.

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Neovascularization of a carotid atherosclerotic plaque (AP) is associated with an increased risk of stroke. Contrast-enhanced ultrasonography (CEUS) is a widely used method for imaging intraplaque neovascularization in vivo. Unfortunately, there are no standardized guidelines for CEUS interpretation. The aim of this study was to identify the most reliable method for CEUS-based assessment of AP neovascularization. Seventy-eight AP were removed during carotid endarterectomy in 73 patients, of whom 5 had AP on both sides, and examined morphologically. All patients underwent preoperative duplex sc

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Quartuccio, Marco, Luigi Liotta, Santo Cristarella, et al. "Contrast-Enhanced Ultrasound in Cystic Endometrial Hyperplasia–Pyometra Complex in the Bitch: A Preliminary Study." Animals 10, no. 8 (2020): 1368. http://dx.doi.org/10.3390/ani10081368.

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In cystic endometrial hyperplasia (CEH)–pyometra syndrome, toxic factors and endometrial remodeling culminate in changes characterized by exudative and degenerative inflammatory reaction. Recent studies on hemodynamic found an increased blood flow and lower vascular resistance in uterine arteries, suggesting color Doppler ultrasound as an adjunctive tool for quantitative assessment of endometrial vascularization during pyometra. The aim of this study was to assess, through contrast-enhanced ultrasound (CEUS) exam, the vascularization in endometrial microvessels in CEH-pyometra in order to eval

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Petrasova, Hana, Radka Slaisova, Tomas Rohan, et al. "Contrast-Enhanced Ultrasonography for Differential Diagnosis of Benign and Malignant Thyroid Lesions: Single-Institutional Prospective Study of Qualitative and Quantitative CEUS Characteristics." Contrast Media & Molecular Imaging 2022 (April 23, 2022): 1–10. http://dx.doi.org/10.1155/2022/8229445.

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Objectives. To extend and revise the diagnostic value of contrast-enhanced ultrasonography (CEUS) for differentiation between malignant and benign thyroid nodules. Methods. This single-institution prospective study aims to compare CEUS qualitative and objective quantitative parameters in benign and malignant thyroid nodules. Consecutive cohort of 100 patients was examined by CEUS, 68 out of them were further analysed in detail. All included patients underwent cytological and/or histopathological verification of the diagnosis. Results. Fifty-five (81%) thyroid nodules were benign, and 13 (19%)

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Cicirelli, Vincenzo, Francesco Macrì, Simona Di Pietro, Raffaella Leoci, Giovanni Michele Lacalandra, and Giulio Guido Aiudi. "Use of Contrast-Enhanced Ultrasound of the Testes after Non-Surgical Sterilization of Male Dogs with CaCl2 in Alcohol." Animals 12, no. 5 (2022): 577. http://dx.doi.org/10.3390/ani12050577.

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Sterilization by intratesticular injection of chemical agents is a non-surgical alternative to neutering male companion animals. We used contrast-enhanced ultrasound (CEUS) to monitor vascular alterations to testes immediately after the intratesticular injection of CaCL2 in alcohol. We evaluated the CEUS features of normal and damaged testes in 20 dogs after the intratesticular injection of CaCl2. The CEUS evaluation was performed at the site of the chemical agent inoculation. In treated testes, qualitative CEUS showed a lower intensity enhancement of the parenchyma than pre-treatment normal t

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Maxeiner, Andreas, Thomas Fischer, Julia Schwabe, et al. "Contrast-Enhanced Ultrasound (CEUS) and Quantitative Perfusion Analysis in Patients with Suspicion for Prostate Cancer." Ultraschall in der Medizin - European Journal of Ultrasound 40, no. 03 (2018): 340–48. http://dx.doi.org/10.1055/a-0594-2093.

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Abstract Purpose The aim of this study was to investigate contrast-enhanced ultrasound (CEUS) parameters acquired by software during magnetic resonance imaging (MRI) US fusion-guided biopsy for prostate cancer (PCa) detection and discrimination. Materials and Methods From 2012 to 2015, 158 out of 165 men with suspicion for PCa and with at least 1 negative biopsy of the prostate were included and underwent a multi-parametric 3 Tesla MRI and an MRI/US fusion-guided biopsy, consecutively. CEUS was conducted during biopsy with intravenous bolus application of 2.4 mL of SonoVue® (Bracco, Milan, Ita

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Schwarz, Sonja, Dirk-André Clevert, Michael Ingrisch, et al. "Quantitative Analysis of the Time–Intensity Curve of Contrast-Enhanced Ultrasound of the Liver: Differentiation of Benign and Malignant Liver Lesions." Diagnostics 11, no. 7 (2021): 1244. http://dx.doi.org/10.3390/diagnostics11071244.

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Background: To evaluate the diagnostic accuracy of quantitative perfusion parameters in contrast-enhanced ultrasound to differentiate malignant from benign liver lesions. Methods: In this retrospective study 134 patients with a total of 139 focal liver lesions were included who underwent contrast enhanced ultrasound (CEUS) between 2008 and 2018. All examinations were performed by a single radiologist with more than 15 years of experience using a second-generation blood pool contrast agent. The standard of reference was histopathology (n = 60), MRI or CT (n = 75) or long-term CEUS follow up (n

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Nedelmann, Max, Nouha Ritschel, Simone Doenges, et al. "Combined Contrast-Enhanced Ultrasound and rt-PA Treatment is Safe and Improves Impaired Microcirculation after Reperfusion of Middle Cerebral Artery Occlusion." Journal of Cerebral Blood Flow & Metabolism 30, no. 10 (2010): 1712–20. http://dx.doi.org/10.1038/jcbfm.2010.82.

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In monitoring of recanalization and in sonothrombolysis, contrast-enhanced ultrasound (CEUS) is applied in extended time protocols. As extended use may increase the probability of unwanted effects, careful safety evaluation is required. We investigated the safety profile and beneficial effects of CEUS in a reperfusion model. Wistar rats were subjected to filament occlusion of the right middle cerebral artery (MCA). Reperfusion was established after 90 minutes, followed by recombinant tissue-type plasminogen activator (rt-PA) treatment and randomization to additional CEUS (contrast agent: SonoV

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Lerchbaumer, Markus H., Katharina Margherita Wakonig, Philipp Arens, Steffen Dommerich, and Thomas Fischer. "Quantitative Multiparametric Ultrasound (mpUS) in the Assessment of Inconclusive Cervical Lymph Nodes." Cancers 14, no. 7 (2022): 1597. http://dx.doi.org/10.3390/cancers14071597.

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Background: Enlarged cervical lymph nodes (CLN) are preferably examined by ultrasound (US) by using criteria such as size and echogenicity to assess benign and suspicious CLN, which should be histologically evaluated. This study aims to assess the differentiation of malign and benign CLN by using multiparametric US applications (mpUS). Methods: 101 patients received a standardized US protocol prior to surgical intervention using B-mode–US, shear-wave elastography (SWE) and contrast-enhanced ultrasound (CEUS). SWE was assessed by 2D real-time SWE conducting a minimum of five measurements, CEUS

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Tikhankova, A. V., A. V. Borsukov, A. O. Buyeverov, V. V. Ivanov, and Yu V. Ivanov. "Improved methods of the contrast-enhanced ultrasound in patient with chronic viral hepatitis." Journal of Clinical Practice 10, no. 1 (2019): 4–9. http://dx.doi.org/10.17816/clinpract1014-9.

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Rationale. The article presents the data obtained by an improved method of contrast-enhanced ultrasound (CEUS) in patients with chronic viral hepatitis. Methods. We compared the quantitative and qualitative CEUS parameters in 2 groups of patients: the 1st group was administered 2.5 ml of the contrast agent, and the 2nd group was administered 1.0 ml of the contrast agent. Results. The results showed that the quantitative parameters had no statistical differences in the arterial and portal phases. Conclusion. The parameters of the late venous phase were not clinically significa

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Li, Hongbo, Hui Huang, Yun Luan, Niu Liu, Hui Gao, and Huijuan Sun. "Contrast-Enhanced Ultrasonography Characteristics in the Evaluation of Different Nature of Carotid Artery Plaques." Journal of Medical Imaging and Health Informatics 10, no. 3 (2020): 688–92. http://dx.doi.org/10.1166/jmihi.2020.2919.

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To investigate the value of contrast-enhanced ultrasonography (CEUS) in the evaluation of neovascular density in plaques with different carotid atherosclerosis. 97 patients with carotid plaques were observed by conventional ultrasound from January 2016 to December 2018. The CEUS test was used to grade and quantify the new blood vessels in the plaque. The results showed of the 97 patients with 101 plaques, 49 were soft plaques, 45 were mixed plaques, and 7 were hard plaques. CEUS clearly showed the continuity of plaque fibrous caps and found plaque ulcers that were easily missed by conventional

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Rogalska, Marta, Lukasz Antkowiak, Anna Kasperczuk, and Wojciech Scierski. "Contrast-Enhanced Ultrasound in the Differentiation between the Most Common Benign Parotid Gland Tumors: A Systematic Review and Meta-Analysis." Journal of Clinical Medicine 11, no. 24 (2022): 7360. http://dx.doi.org/10.3390/jcm11247360.

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Recently, contrast-enhanced ultrasound (CEUS) has become a promising tool in distinguishing benign from malignant parotid gland tumors. However, its usefulness in differentiating various benign parotid tumors has not been determined so far. This study aimed to systematically review the literature to determine the utility of CEUS in the preoperative differentiation between pleomorphic adenomas (PAs) and Warthin’s tumors (WTs) of the parotid gland. PubMed, Embase, and Cochrane were searched for English-language articles published until 21 July 2022. Fifteen studies were included. On CEUS examina

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Marticorena Garcia, S., J. Schwabe, E. Jung, and T. Fischer. "Quantitative Perfusionsanalyse mittels Kontrastmittelsonografie (CEUS) zur Differenzierung eines aggressiven Prostatakarzinoms." RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren 189, S 01 (2017): S1—S124. http://dx.doi.org/10.1055/s-0037-1600496.

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Weber, Marc-André, Martin Krix, and Stefan Delorme. "Quantitative evaluation of muscle perfusion with CEUS and with MR." European Radiology 17, no. 10 (2007): 2663–74. http://dx.doi.org/10.1007/s00330-007-0641-y.

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Ma, Jiuyi, Ying Fu, Xiangmei Chen, et al. "Utilizing the Postvascular Phase of Contrast-Enhanced Ultrasound to Predict Breast Cancer Lymph Node Metastasis." Medicina 60, no. 11 (2024): 1780. http://dx.doi.org/10.3390/medicina60111780.

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Background and Objectives: To evaluate the value of the postvascular phase of contrast-enhanced ultrasound (CEUS) in differentiating between benign and metastatic lymph nodes (LNs) in patients with breast cancer (BC). Materials and Methods: This study retrospectively analyzed 96 suspicious LNs in the lymphatic drainage area of the breast from 90 patients with BC. All LNs were assessed by conventional ultrasound (US) and CEUS following intravenous Sonazoid injection. All LNs underwent puncture biopsy, and pathological results were obtained. The correlations between US and CEUS indicators of LNs

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Han, Seul Ki, Soon Koo Baik, and Moon Young Kim. "New Applications of Contrast-Enhanced Ultrasound for Hepatic Fibrosis and Portal Hypertension." Clinical Ultrasound 8, no. 2 (2023): 66–71. http://dx.doi.org/10.18525/cu.2023.8.2.66.

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Liver biopsy and measurement of hepatic venous pressure gradient in patients with cirrhosis are the gold standards for estimation of hepatic fibrosis, and they have diagnostic and prognostic value. However, both approaches are invasive and cannot be used repeatedly in clinical practice. Ultrasonography (US) is safe, easy to perform, inexpensive, and yields numerical and accurate results. Contrast-enhanced US (CEUS) using second-generation microbubble ultrasonography agents (USA) is able to show the vascular structure and enhancement pattern of lesions and can be used in the diagnosis of hepato

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Tufano, Antonio, Francesco Maria Drudi, Flavia Angelini, et al. "Contrast-Enhanced Ultrasound (CEUS) in the Evaluation of Renal Masses with Histopathological Validation—Results from a Prospective Single-Center Study." Diagnostics 12, no. 5 (2022): 1209. http://dx.doi.org/10.3390/diagnostics12051209.

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Background: To evaluate the diagnostic accuracy of contrast-enhanced ultrasound (CEUS) in characterizing between malignant and benign renal lesions confirmed by histological examination. Methods: Overall, 110 patients, for a total of 118 renal masses previously identified at CT and MRI underwent CEUS. An expert radiologist evaluated morphological, qualitative and quantitative parameters. Acquired data were analyzed to assess the value of each parameter to differentiate between malignant and benign lesions. Results: Histological results of 118 renal masses showed 88 (75%) malignant lesions and

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Simeoni, Francesco, Rossella Terragni, Giuseppe Rubini, et al. "B-Mode and Contrast Enhanced Ultrasonography Features of Gastric Inflammatory and Neoplastic Diseases in Cats." Animals 10, no. 8 (2020): 1444. http://dx.doi.org/10.3390/ani10081444.

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Alimentary lymphoma (AL) is the most common malignancy of the feline gastrointestinal tract and may cause variable mild to severe alteration of the gastric wall on ultrasonography (US) that can be very similar to those caused by inflammation (INF). The aim of this prospective study is to establish the value of B-mode and contrast-enhanced US (CEUS) in describing specific features of normal, inflammatory, and neoplastic gastric diseases in feline species. B-mode US and CEUS of the stomach were performed in anesthetized cats with or without gastric disorders. Gastric wall qualitative and quantit

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Yi, Huiming, Baohuan Cai, Xi Ai, Kaiyan Li, Pengfei Song, and Wei Zhang. "Early Identification of Residual Tumors following Microwave Ablation Using Contrast-Enhanced Ultrasonography in a Rabbit VX2 Liver Cancer Model." BioMed Research International 2020 (September 27, 2020): 1–9. http://dx.doi.org/10.1155/2020/2462058.

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Objective. It is difficult to evaluate the ablation effect immediately after thermal ablation of liver cancer by clinical imaging methods, due to the immediate formation of an annular inflammatory reaction band (IRB). This study is aimed at exploring the early identification indicators of the IRB and residual tumor postmicrowave ablation (MVA) using contrast-enhanced ultrasonography (CEUS). Methods. MVA was used to inactivate part of the tumor nodules in rabbit VX2 liver cancer models, leading to the coexistence of the IRB with residual tumors. Quantitative analysis of the perfusion parameters

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Sun, Di, Qijie Lu, Cong Wei, Yi Li, Yuanyi Zheng, and Bing Hu. "Differential diagnosis of <3 cm renal tumors by ultrasonography: a rapid, quantitative, elastography self-corrected contrast-enhanced ultrasound imaging mode beyond screening." British Journal of Radiology 93, no. 1112 (2020): 20190974. http://dx.doi.org/10.1259/bjr.20190974.

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Objectives: To assess the combined diagnostic strategy of contrast-enhanced ultrasound (CEUS) and acoustic radiation force impulse (ARFI) in the precise differential diagnosis of clear cell renal cell carcinoma (CCRCC) and urothelium carcinoma of the renal pelvis (UCRP) with other small renal tumors (SRTs) ＜3 cm in size. Methods: The elastography self-corrected CEUS (ESC) mode was established to perform the quantitative differential diagnosis of SRTs (<3 cm). The kidney shear wave velocity (SWV) value recorded by ARFI showed substantial variability in patients with CCRCC (high elasticity va

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Kaiser, Ulrich, Ursula Vehling-Kaiser, Fabian Kück, Mia Gilanschah, Friedrich Jung, and Ernst Michael Jung. "Super-Resolution Contrast-Enhanced Ultrasound Examination Down to the Microvasculature Enables Quantitative Analysis of Liver Lesions: First Results." Life 15, no. 7 (2025): 991. https://doi.org/10.3390/life15070991.

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This article investigates the first use of dynamic microvascularization of liver lesions in clinical evaluation using real-time super-resolution contrast-enhanced ultrasound (SR CEUS). A retrospective analysis of SR CEUS examinations of liver lesions was performed. All examinations were conducted using an SC7-1U convex probe after the bolus injection of the ultrasound contrast agent. Digital cine loops were stored for independent evaluation. The evaluation was performed with respect to parallel measuring lines (the diameter corresponded to the capillary density) in the area of the reference le

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Bueverov, Аlexey O., Аlexey V. Borsukov, and Anna V. Tikhankova. "Assessment of the vascular structure of the liver in viral hepatitis by contrast-enhanced ultrasound." Terapevticheskii arkhiv 96, no. 2 (2024): 91–96. http://dx.doi.org/10.26442/00403660.2024.02.202580.

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Aim. To determine the diagnostic and prognostic value of contrast-enhanced ultrasound (CEUS) in assessment of the vascular structure of the liver in patients with chronic viral hepatitis. Materials and methods. Based on Clinical hospital №1 in Smolensk from 2018 to 2019 120 people with chronic viral hepatitis and 35 people with unchanged liver parenchyma as a control group were included in the study. All patients were examined by CEUS with 1,0 ml of contrast agent with subsequent evaluation of qualitative and quantitative parameters. Results. In statistical data processing it was f

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Freitas, M., V. Macedo Silva, C. Arieira, et al. "P134 Ultrasonographic scores for Crohn’s disease activity assessment – still lag behind CEUS." Journal of Crohn's and Colitis 15, Supplement_1 (2021): S222—S223. http://dx.doi.org/10.1093/ecco-jcc/jjab076.261.

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Abstract Background Intestinal ultrasound (IUS) is an increasingly used non-invasive tool to monitor Crohn‘s disease (CD) activity. Currently, there is no widely accepted, reproducible IUS activity index to evaluate inflammatory activity. In 2020, two new scores emerged: the Simple Ultrasound Activity Score for CD (SUS-CD) and International Bowel Ultrasound Segmental Activity Score (IBUS-SAS). We aimed to compare the accuracy of SUS-CD, IBUS-SAS and contrast ultrasound (CEUS) in predicting inflammatory activity in the terminal ileum in ileocolonoscopy. Methods Retrospective study including all

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Simeoni, Francesco, Francesca Del Signore, Giovanni Aste, et al. "B-Mode and Contrast Enhanced Ultrasonography Features of Gastric Inflammatory and Neoplastic Diseases in Dogs." Animals 11, no. 3 (2021): 670. http://dx.doi.org/10.3390/ani11030670.

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Canine gastric disorders are common in veterinary clinical practice and among these neoplasms require rapid identification and characterization. Standard ultrasound (US) is the imaging modality of choice for gastric wall assessment. The aim of this prospective study is to describe the specific B-mode and contrast enhanced US (CEUS) features of normal, inflammatory, and neoplastic gastric wall in dogs. B-mode US and CEUS of the stomach were performed in anesthetized dogs with or without gastric disorders. Gastric wall qualitative and quantitative parameters were evaluated on B-mode US and CEUS

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Wu, Hailan, Jiayu Shi, Long Gao, et al. "Qualitative and quantitative analysis of solid renal tumors by high-frame-rate contrast-enhanced ultrasound." Cancer Imaging 24, no. 1 (2024). http://dx.doi.org/10.1186/s40644-024-00788-3.

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Abstract Objective To analyze the characteristics of high-frame-rate contrast-enhanced ultrasound (H-CEUS) in solid renal tumors using qualitative and quantitative methods. Methods Seventy-five patients who underwent preoperative conventional ultrasound (US), conventional contrast-enhanced ultrasound (C-CEUS), and H-CEUS examination of renal tumors were retrospectively analyzed, with a total of 89 renal masses. The masses were divided into the benign (30 masses) and malignant groups (59 masses) based on the results of enhanced computer tomography and pathology. The location, diameter, shape, b

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Cao, Jiaying, Yi Dong, Peili Fan, et al. "Early evaluation of treatment response to transarterial chemoembolization in patients with advanced hepatocellular carcinoma: The role of dynamic three-dimensional contrast-enhanced ultrasound." Clinical Hemorheology and Microcirculation, March 5, 2021, 1–13. http://dx.doi.org/10.3233/ch-201086.

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BACKGROUND: Dynamic three-dimensional contrast-enhanced ultrasound (3D-CEUS) with quantitative analysis is available in recent years. It can reduce the quantitative sampling error caused by the inconsistency of different sections in order to evaluate local treatment response of hepatocellular carcinoma (HCC) accurately. OBJECTIVE: To investigate the value of dynamic 3D-CEUS in evaluating the early response to transarterial chemoembolization (TACE) treatment in patients with advanced HCC lesions. METHODS: In this prospective study, both two-dimensional (2D) CEUS and dynamic 3D-CEUS were perform

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Li, Jiajia, Yunfeng Wu, Zhaoyu Tian, Linfeng Shu, Siru Wu, and Zuohui Wu. "Application Value of Ultrasound Elastography Combined With Contrast-Enhanced Ultrasound (CEUS) Quantitative Analysis in Differentiation of Nodular Fibrocystic Changes of the Breast From Invasive Ductal Carcinoma." Ultrasonic Imaging, December 14, 2023. http://dx.doi.org/10.1177/01617346231217087.

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This study aimed to compare the value of ultrasound elastography combined with contrast-enhanced ultrasound (CEUS) quantitative analysis in the differentiation of nodular fibrocystic breast change (FBC) from breast invasive ductal carcinoma (BIDC). We selected 50 patients each with nodular FBC and BIDC, who were admitted to the Affiliated Hospital of Zunyi Medical University from January 2018 to December 2021. Their ultrasonic elastic images and CEUS videos were collected, their ultrasound elastography scores and the ratio of strain rate (SR) of the lesions were determined, and the exported DI

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Dillman, Jonathan R., Adam F. Prasanphanich, Katherine N. Epstein, Alexander J. Towbin, and Andrew T. Trout. "Contrast-enhanced ultrasound of Crohn’s disease in children and young adults: quantitative metric correlations and MRI disease severity associations." Pediatric Radiology, March 13, 2025. https://doi.org/10.1007/s00247-025-06203-8.

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Abstract Background There is a paucity of data comparing contrast-enhanced ultrasound (CEUS) to MR enterography in children and young adults with Crohn’s disease. Objective To measure correlations across CEUS quantitative metrics in children and young adults with Crohn’s disease, and to evaluate if these metrics are associated with MRI features of disease activity. Materials and methods Patients <21 years old with Crohn’s disease affecting the terminal ileum who underwent clinically-indicated MR enterography were recruited between 2021 and 2024. Research CEUS of the terminal ileum was perfo

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Badiu, Simona Maria, Elena Codruța Gheorghe, Carmen Nicolau, and Adrian Săftoiu. "Quantitative time intensity curve analysis of contrast-enhanced ultrasound (CEUS) examinations for the assessment of focal liver lesions." Medical Ultrasonography, November 6, 2023. http://dx.doi.org/10.11152/mu-4108.

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Contrast enhanced ultrasound (CEUS) is well-established for the characterization of focal liver lesions (FLLs). By using intravenous ultrasound contrast agents, followed by specific low mechanical index examinations, CEUS enables a high spatial and temporal resolution as well as a dynamic assessment of macro- and microvascularization down to the capillaries. Nevertheless, CEUS has the disadvantage of being examiner-dependent, so quantitative analysis of time-intensity curves in dynamic CEUS (D-CEUS) could provide further information. The aim of this article is to provide a general review of th

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