Journal articles: 'Quality use of medicines'

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Thomas, Dixon, Kishore Gnana Sam Sundararaj, Annie Shirwaikar, and Arun Shirwaikar. "Quality Use of Quality Medicines." Journal of Pharmacy Practice and Community Medicine 3, no. 2 (March 31, 2017): 41–42. http://dx.doi.org/10.5530/jppcm.2017.2.11.

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Hassali, Azmi, Kay Stewart, and David Kong. "Quality use of generic medicines." Australian Prescriber 27, no. 4 (August 1, 2004): 80–81. http://dx.doi.org/10.18773/austprescr.2004.067.

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Dixit, Avika, Neeta Kumar, and Sanjiv Kumar. "Use of Generic Medicines." Journal of Health Management 20, no. 1 (January 23, 2018): 84–90. http://dx.doi.org/10.1177/0972063417747747.

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The government is committed to make healthcare affordable as stated in the National Health Policy 2017. An estimated 94 million people in India are pushed into poverty due to expenditure on healthcare. About two thirds of the expenditure is incurred on medicines. Generic medicines are as effective as branded medicines. The initiative of the government and Medical Council of India by making it mandatory for doctors to write generic medicines has raised many concerns related to generic drugs availability and quality. Experience in the USA and Canada support the argument in favor of generic medicine. India is the main supplier of the generic medicines to the USA. There is a need to curtail inducement by pharmaceutical companies to promote their branded drugs as is being done in the USA. The government needs to make generic drugs easily available, strengthen quality control and educate doctors on benefits of using generic drugs.

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Smith, Anthony J. "The quality (of) use of medicines." Medical Journal of Australia 165, no. 1 (July 1996): 8–9. http://dx.doi.org/10.5694/j.1326-5377.1996.tb124807.x.

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Brien, Jo-anne E. "Access and Quality Use of Medicines." Journal of Pharmacy Practice and Research 37, no. 1 (March 2007): 10. http://dx.doi.org/10.1002/j.2055-2335.2007.tb00648.x.

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Barrett, David. "Responsible use of medicines and medicine recording." Livestock 25, no. 6 (November 2, 2020): 298. http://dx.doi.org/10.12968/live.2020.25.6.298.

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In his presentation at the UK-Vet Healthy Herd 2020 Digital Event on 21st October 2020 Professor Barrett spoke to a mixed audience of both farmers and veterinary surgeons. His talk on the ‘Responsible use of medicines and medicine recording’ in livestock, explained the key factors that influence best-practice treatment decisions within the context of legislation, quality assurance and market demand.

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Nicha, Vasilka, Maja Simonoska Crcarevska, Marija Glavas Dodov, and Renata Slaveska Raichki. "Quality use of an unlicensed medicine and off label use of a medicine." Macedonian Pharmaceutical Bulletin 60, no. 01 (2014): 61–69. http://dx.doi.org/10.33320/maced.pharm.bull.2014.60.01.008.

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This paper gives an overview of the concept and process of quality use of unlicensed medicines and off label use of medicines, with special attention on the professional roles and responsibilities of prescribers and pharmacists. It also focuses on the policy requirements, sets of guidelines, recommendations, best practices, and other aspects addressed under this topic that represent the state of update knowledge. As a complex and specific issue, the use of an unlicensed medicine and off label prescribed medicine in different health care levels is of particular importance for the healthcare settings in the Republic of Macedonia since, the existing regulatory structure requires adoption and development of a comprehensive strategy relating to this topic in the near future with an aim of encouraging and supporting the development and maintenance of a sound health system with high standards of medication-use policies.

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Jain, Sachin Kumar. "Standardization & Safety Measures: Quality-Based Validation of Herbal Medicine." International Journal of Pharmacognosy & Chinese Medicine 3, no. 4 (2019): 1–3. http://dx.doi.org/10.23880/ipcm-16000182.

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Herbal medicines magnetize the curiosity of both patients and scientists, in all aspects of drug development from natural products and also for rationale of traditional medicine (TM). Numerous developing countries rely on TM because of their convenience and affordability, and scientists all over the world believe medicinal plants as a resource of new chemical entities and use them to isolate compounds such as Sennoside, quinine, strychnine, digoxin, morphine, taxol, atropine, and vinblastine

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Rathod, Rucha, and Raman R. Chandak. "Review on “Standardization an Imp Tool for Herbal Drug Development”." Journal of Drug Delivery and Therapeutics 9, no. 6-s (December 15, 2019): 253–57. http://dx.doi.org/10.22270/jddt.v9i6-s.3784.

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The medicinal plants are important source for pharmaceutical manufacturing. Medicinal plants & herbal medicines account for a significant percentage of the pharmaceutical market. There is increasing awareness and general acceptability of the use of herbal drugs in today’s medical practice although most of these applications are not scientific. Herbal medicines are not a simple task since many factors influence the biological efficacy and Reproducible therapeutic effect. So it is necessary to improve safety of herbal drugs by developing certain quality control parameters & by following the WHO guidelines for herbal medicines. This review seeks to enlighten the need to establish quality parameters for collection, handling, processing and production of herbal medicine as well as employ such parameters in ensuring the safety of the global herbal market. It is necessary to introduce measures on the regulation of herbal medicines to ensure quality, safety, efficacy of herbal medicines by using modern suitable standards & GMP. The processes of good quality assurance and standardization of herbal medicines and products using various spectroscopic, chromatographic and electrophoretic methods were also discussed. In fact, the research field of quality control of herbal medicines is really an interdisciplinary research. It needs crossover of chemistry, pharmacology, medicine and even statistics to provide a platform for the quality control of traditional herbal medicines and further to discover the novel therapeutics composed of multiple chemical compounds. Keywords: Herbal drugs, Adulteration, Standardization, Chromatography, Electrophoresis, HP-LC and GC-MS.

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Raina, M. K. "EMERGING TRENDS IN QUALITY CONTROL OF HERBAL MATERIALS." INDIAN DRUGS 55, no. 08 (August 28, 2018): 5–6. http://dx.doi.org/10.53879/id.55.08.p0005.

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The therapeutic use of medicinal plants gained considerable momentum in the world during the past few decades. Traditional medicines, which are mostly based on the herbal raw materials growing in their respective regions, were used by over 70 percent of the world population as per WHO. The reason for their popularity was due to non-availability of modern medicines in the rural areas and also due to the unaffordability of modern medicines due to their high cost. Quality control of medicinal plants for use in these Traditional medicines has always been a challenge for the scientists working in this field. In our country, with the awareness growing among the people about the safety of Ayurvedic and Herbal medicines / cosmetics, the quality control testing of both raw herbal ingredients and finished formulations was seriously undertaken both by the academic / research institutions and the herbal drug manufacturers.

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Sri Astari, Putu Devie. "Role of Students in Agromedicine Development Through Health Promotion to Improve Health Quality in Indonesia." JIMKI: Jurnal Ilmiah Mahasiswa Kedokteran Indonesia 8, no. 2 (August 22, 2020): 176–82. http://dx.doi.org/10.53366/jimki.v8i2.159.

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ABSTRACTBackground: Health problems in Indonesia are caused by Non-Communicable Diseases (PTM). Degenerative disease is one of the most common problems and is related to antibiotic resistance. The development of agromedicine is very potential in Indonesia because it has the fourth largest bioverity in the world and abundant natural resources. Consumption of herbal medicine as traditional medicine has an effect on healing degenerative diseases. Herbal medicines are sourced from medicinal plants as a medical identity in Indonesia in terms of developing agromedicine.Discussion: The use of traditional Indonesian medicines has become a national culture because Indonesia is a mega-center of medicinal plants in the world. Development ofagromedicine in the field of herbal medicines requires contributions from various related parties including students, media service providers, the government, producers and research institutions. Health promotion method is a form of information delivery that aims to change people's behavior through the active role of students as agents of change.Conclusion: Optimizing the use of agromedicine is needed to meet the needs of high-quality national medicines. All parties make a major contribution in achieving the goals. Students as agents of change can do health promotion to the community so as to realize prosperity by utilizing natural resources available in Indonesia.

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Dowden, John S. "Quality Use of Medicines-a Canberra Contribution." Australian Journal of Hospital Pharmacy 28, no. 2 (April 1998): 78–79. http://dx.doi.org/10.1002/jppr199828278.

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Ndukwe, Henry C., Prasad S. Nishtala, Ting Wang, and June M. Tordoff. "Quality use of antipsychotic medicines inresidential aged care facilities in New Zealand." Journal of Primary Health Care 8, no. 4 (2016): 335. http://dx.doi.org/10.1071/hc15054.

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ABSTRACT INTRODUCTION Antipsychotic medicines are used regularly or when required in residential aged care facilities to treat symptoms of dementia, but have been associated with several adverse effects. AIM The aim of this study was to examine ‘quality use’ of antipsychotic medicines in residential aged care facilities in New Zealand, by surveying nurse managers. METHODS A cross-sectional survey was mailed to 318 nurse managers working in a nationally representative sample of aged care facilities. A purpose-developed, pre-tested, 22-item structured questionnaire was used to explore practice related to the quality use of antipsychotic medicines. RESULTS Overall, 31.4% of nurse managers responded to the survey. They mostly (88%) had ≥ 1 year’s relevant work experience and 83% of facilities provided care for those within the range of 21 to 100 residents. Respondents reported that staff education on dementia management occurred early in employment. Two-thirds of participants reported non-pharmacological interventions were commonly used for managing challenging behaviours, while less than half (45%) cited administering antipsychotic medicine. Respondents reported ‘managing behavioural symptoms’ (81%) as one of the main indications for antipsychotic use. Frequently identified adverse effects of antipsychotic medicines were drowsiness or sedation (64%) and falls (61%). Over 90% reported general practitioners reviewed antipsychotic use with respect to residents’ target behaviour 3-monthly, and two-thirds used an assessment tool to appraise residents’ behaviour. DISCUSSION Staff education on dementia management soon after employment and resident 3-monthly antipsychotic medicine reviews were positive findings. However, a wider use of behavioural assessment tools might improve the care of residents with dementia and the quality use of antipsychotic medicines.

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Shaydullina, L. Y., and L. E. Ziganshina. "Rational use of medicines: contribution to development of healthcare systems." Kazan medical journal 93, no. 5 (October 15, 2012): 803–6. http://dx.doi.org/10.17816/kmj1715.

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Development of World Health Organization (WHO) Rational Use of Medicines concept internationally and its implementation in the Russian Federation is reviewed. The need to consolidate efforts for the introduction of the WHO-developed strategy for the use of medicines improvement is explained. The WHO strategy to improve the use of medicines is described. Abundance of medicines, medicinal products and various formulations of the same active substances, as well as of promotional materials, which often mislead healthcare community and consumers, requires establishment of a system promoting effective and safe use of medicines and ensuring access to essential medicines of all members of the society. The factors which contribute to irrational use of medicines, avoidable causes, and consequences of irrational use of medicines are presented. Current situation in the Russian Federation regarding the use of medicines: legal and regulatory framework, the results of the registration process, documents valid on a national level and in particular regions that determine pharmaceutical policy is described in detail. Methodology of assessing prescribing practices and medicine consumption recommended by the World Health Organization for implementation and use globally is revealed. The implementation of the WHO concept of the rational use of medicines in the Republic of Tatarstan is described as an example. An illustration of the authors’ findings on effects of clinical pharmacology services on containment of medicines’ costs at the level of internal diseases department of municipal hospital is presented. The leading thesis of WHO Rational Use of Medicines concept - the establishment of independent multidisciplinary regional structures responsible for the quality use of medicines - is substantiated.

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Mirzaeian, Razieh, Farahnaz Sadoughi, Shahram Tahmasebian, and Morteza Mojahedi. "The role of herbal medicines in health care quality and the related challenges." Journal of Herbmed Pharmacology 10, no. 2 (January 5, 2021): 156–65. http://dx.doi.org/10.34172/jhp.2021.17.

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In recent years, there has been a renewed interest in the use of herbal medicines. Quality control and safety are two critical principles to be considered in the production process of herbal medicines. This review study aimed to investigate the condition of the countries other than Iran in terms of observing the safety principles, quality control, and meeting the standard of herbal drug use. In this systematic review, references were selected using the search terms "health-care quality" and "challenges of herbal medicine usage" from the databases "Web of Science" and "PubMed" published between 2000 and 2019. To select the resources among the selected literature, confirmation was accomplished by two researchers and Cohen’s kappa coefficient (κ). The selected papers were classified based on publication year, journal, country, reference standards, regulation, toxicity evaluation, quality control, efficacy, safety, and adverse effects in herbal medicine. From 1532 retrieved papers, 27 papers with an estimated Cohen’s kappa coefficient of 0.81 were confirmed and included in the study. Based on the analysis, the main findings of the papers were thematically classified into seven subcategories as follows: reference standards in herbal medicine, regulation of herbal medicinal products, toxicity evaluation for herbal products, quality control of herbal medicine, efficacy, adverse effects of herbal medicine, and safety. Given the significance of the effects of herbal medicines on health care quality, it is essential to codify guidelines on the proper use of these drugs.

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Restyana, Anggi, Khalimatus Nur Eka Agustanti, Lisa Savitri, and Nur Fahma Laili. "The Relationship Between the Perception of Traditional Medicine Use and the Quality of Community Life in Pulungdowo Village, Tumpang Sub-District, Malang Regency." Journal for Quality in Public Health 4, no. 1 (November 30, 2020): 192–201. http://dx.doi.org/10.30994/jqph.v4i1.139.

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Background Public interest in use of traditional medicines in Indonesia is high. Community in Pulungdowo is one of them. Use of traditional medicines can support the QoL community for their safety and benefits. Measurement of QoL was carried out using Short Form (SF-36). Purpose was to determine relationship between perception of the use of traditional medicine and QoL of the community in Pulungdowo. Methods used descriptive analytic method with quantitative approach using purposive sampling method. Retrieval of research data used questionnaires distributed to 100 respondents in Pulungdowo. Result perception of the use of traditional medicine obtained a total score of 29; mean = 25.65 and SD = 4.89. On QoL of community showed results of average value of each sub-variable QoL that is more than 50. Analysis test of relationship between perception of the use of traditional medicines with QoL, results obtained with a sig 0,000. Conclusion respondents perceptions on the use of traditional medicines was good which meant that respondents could receive and process information well about the use of traditional medicines. In addition, QoL of community after using traditional medicines was also said to be good. Results of the analysis of relationship between perception of the use of traditional medicine and QoL of Pulungdowo showed that there was a relationship between perception of the use of traditional medicine and QoL community. It is needed to improve health promotion programs such as counselling about introduction of traditional medicine types regarding to large number of people only know herbal medicines.

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Morris, Steve. "Safe and sound: applying quality use of medicines to high‐risk medicines." Journal of Pharmacy Practice and Research 48, no. 6 (December 2018): 498–500. http://dx.doi.org/10.1002/jppr.1518.

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Shah, Bibha, and Nabaraj Pokhrel. "Microbial Quality and Antibacterial Activity of Herbal Medicines." Nepal Journal of Science and Technology 13, no. 2 (March 10, 2013): 191–96. http://dx.doi.org/10.3126/njst.v13i2.7735.

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Use of herbal medicine faces constraint particularly imparting knowledge in identifying whether a product is microbiologically fit for health or not. There has been relatively less research on microbial quality of the herbal medicines in Nepal. In this context, this research has focused on microbial quality of different herbal medicines. A total of twenty one herbal medicines were collected from different sales outlet of Kathmandu. The microbial load in herbal medicine was determined by aerobic plate count method and bacterial isolates were identified based on morphological, cultural and biochemical tests. Out of twenty one herbal medicines analyzed, all were found free from pathogenic bacteria and indicator organism of fecal contamination. However , Bacillus spp. were isolated from ten herbal medicines. The microbial load on Nutrient Agar was found within the range of 1.20x103- 6.06x105 cfu/ ml (or g). Altogether six different Bacillus spp were identified and the most predominant was Bacillus subtilis. In vitro antibacterial activity of the herbal medicines, from which microorganisms were not detected, were determined against six test bacteria by cup plate method. Out of eleven different herbal medicines, five showed the zone of inhibition against all test bacteria and at least two test bacteria were inhibited by each of the herbal medicines. The highest zone of inhibition was 30 mm shown by Chitrakaharitaki Churna of concentration 100mg/ml against Pseudomonas aeruginosa. Nepal Journal of Science and Technology Vol. 13, No. 2 (2012) 191-196 DOI: http://dx.doi.org/10.3126/njst.v13i2.7735

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Moulds, Robert F. W. "Editorial: Quality use of medicines - where to next?" Australian Prescriber 21, no. 3 (June 1, 1998): 58–59. http://dx.doi.org/10.18773/austprescr.1998.056.

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Hirshorn, Janice E. "Letters to the Editor: Quality use of medicines." Australian Prescriber 22, no. 1 (February 1, 1999): 3–5. http://dx.doi.org/10.18773/austprescr.1999.005.

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Wilkin, Mary, Andrew McLachlan, and Ian Coombes. "Cost shifting and the quality use of medicines." Australian Prescriber 38, no. 1 (February 1, 2015): 3–5. http://dx.doi.org/10.18773/austprescr.2015.007.

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Lehmann, Jayne. "Quality use of medicines for people with diabetes." Collegian 4, no. 2 (January 1997): 33–35. http://dx.doi.org/10.1016/s1322-7696(08)60219-x.

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Tett, Susan, and Elizabeth Roughead. "Quality Use of Medicines-Onwards Up the Pyramid." Australian Journal of Hospital Pharmacy 30, no. 5 (October 2000): 191–92. http://dx.doi.org/10.1002/jppr2000305191.

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Weekes, Lynn. "Quality Use of Medicines and the Life Journey." Journal of Pharmacy Practice and Research 39, no. 3 (September 2009): 172–74. http://dx.doi.org/10.1002/j.2055-2335.2009.tb00445.x.

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Li, Zhiyong, Caifeng Li, Xiaobo Zhang, Shihuan Tang, Hongjun Yang, Xiuming Cui, and Luqi Huang. "Policies and Problems of Modernizing Ethnomedicine in China: A Focus on the Yi and Dai Traditional Medicines of Yunnan Province." Evidence-Based Complementary and Alternative Medicine 2020 (August 14, 2020): 1–14. http://dx.doi.org/10.1155/2020/1023297.

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Yunnan is a multiethnic province in southwest China, rich in Materia medica resources, and is popularly known as the kingdom of plants. Biomedicine and public health industry have been the industrial pillars of Yunnan since 2016, which is the important pharmaceutical industrial base for Dai and Yi medicine in China. This review of the Yunnan ethnic medicine industry describes some of the problems to be solved in the development of sustainable ethnomedicine in China. We investigated Chinese patent medicines (CPMs) declared as ethnomedicine on the drug instructions and identified 28 Dai patent medicines (DPMs) and 73 Yi patent medicines (YPMs) that were approved for clinical use in China. In further research, the clinical indications of these CPMs were determined, and the quality standard of medicinal materials and their usage frequencies in DPMs and YPMs were investigated. We also collected and analyzed the data on use of botanical and animal sources of medicines, the rare and endangered medicinal materials, and toxic medicines in DPMs and YPMs. The application of zootherapy in Yi traditional medicine was introduced from its abundant ancient documents and records; based on the “YaGei” theory in Dai traditional medicine, toxic medicines can be relatively safe in DPMs. However, for promoting the Yunnan traditional medicine industry, it is necessary to strengthen medical research to expand evidence-based clinical practice and balance ethnomedicine production and sustainable utilization of Materia medica resources, especially the animal sources of medicines, toxic medicines, and the protected wild resources reported in this survey. Only in this way can industrialization of ethnomedicine promote the improvement of human health.

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Hauk, Cathrin, Nhomsai Hagen, and Lutz Heide. "Identification of Substandard and Falsified Medicines: Influence of Different Tolerance Limits and Use of Authenticity Inquiries." American Journal of Tropical Medicine and Hygiene 104, no. 5 (May 5, 2021): 1936–45. http://dx.doi.org/10.4269/ajtmh.20-1612.

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ABSTRACTSubstandard and falsified medicines have severe public health and socioeconomic effects, especially in low- and middle-income countries. The WHO has emphasized the need for reliable estimates of the prevalence of such medicines to efficiently respond to this problem. In the present study, we used 601 medicine samples collected in Cameroon, the DR Congo, and Malawi to assess the rates of substandard and falsified medicines based on different criteria. Based on the specifications of the U.S. Pharmacopoeia for the amount of the active pharmaceutical ingredients, the rate of out-of-specification medicines was 9.3%. By contrast, this rate ranged from 3.3% up to 35.0% if the tolerance limits of other pharmacopoeias or recently published medicine quality studies were used. This shows an urgent need for harmonization. Principal methods to assess the rate of falsified medicines are packaging analysis, chemical analysis, and authenticity inquiries. In the present study, we carried out an authenticity inquiry for the aforementioned medicine samples, contacting 126 manufacturers and 42 distributors. Response rates were higher for samples stated to be manufactured in Asia (52.4%) or Europe (53.8%) than for samples manufactured in Africa (27.4%; P < 0.001). One sample had been identified as falsified by packaging analysis by the local researchers and two additional ones by chemical analysis. Notably, seven additional falsified samples were identified by the authenticity inquiries. The total rate of falsified medicines resulted as 1.7%. Considerations are discussed for assessing the rates of “substandard” and “falsified” medicines in future medicine quality studies.

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Petkova, Valentina, Bozhidarka Hadzhieva, and Paraskev Nedialkov. "Phytotherapeutic approaches to treatment and prophylaxis in pediatric practice." Pharmacia 66, no. 3 (November 7, 2019): 115–19. http://dx.doi.org/10.3897/pharmacia.66.e37954.

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Medicinal plants, their extracts and herbal medicinal products occupy a growing share of medicines in the pharmacy worldwide. Historically, the first medicines were products of plants, as well as some of the most important medicines still in use today. With the development of phytochemistry, as part of the pharmaceutical science, great progress has been made in the isolation and in determining the value of a number of biologically active substances (BAS). Many plants have yielded pure substances (or natural products) that are applied in modern medical practice. Other compounds are potentially useful or have toxic effects. Traditional medicine incorporating many herbal medicines remains an important (and in some cases, the only) form of treatment in some countries, with increasing use in medical practice. On the other hand, the fact that in pediatric patients there is a limitation, mainly moral and ethical, of the number of medications to be administered due to the difficulty of conducting clinical trials in children, stimulates the use of herbal medicines of proven quality, effectiveness and safety among this group of patients.

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Onyambu, Meshack O. "A Review of Trends in Herbal Drugs Standardization, Regulation and Integration to the National Healthcare Systems in Kenya and the Globe." International Journal of Pharmacognosy & Chinese Medicine 3, no. 3 (2019): 1–13. http://dx.doi.org/10.23880/ipcm-16000168.

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Herbal medicines contribute to the provision of primary healthcare to millions of people in the world today. With increasing disease burden, there is proportionate increase in demand for those medicines with ethnobotanical evidence of efficacy against communicable and noncommunicable diseases. Because of availability, acceptability and affordability, herbs along with other forms of complementary and alternative medicines have the potential to fulfill the need for universal health coverage as envisaged by world health organization. In this paper, we review the status of herbal medicine use in Kenya and selected countries with a view to highlighting the reasons why some countries have been able to integrate while others have not. There is a general observation that those countries that have been able to define measures for quality assurance and standardization have integrated herbal medicines to their mainstream healthcare systems and have well defined regulatory systems. We conclude that quality remains a challenge and suggest possible approaches for quality control as recommended by WHO. There is a further urgent need to formulate quality assurance mechanisms for highly utilized medicinal products especially for African countries who heavily rely on these forms of medicines for their primary healthcare.

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Graudins, Linda V. "National Medicines Symposium: Pharmacists are an Integral Component of Quality Use of Medicines." Journal of Pharmacy Practice and Research 34, no. 3 (September 2004): 201–2. http://dx.doi.org/10.1002/jppr2004343201.

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Mustafa Din, Wardah, and Noor Ashikeen Zainal Abidin. "KNOWLEDGE AND PRACTICE TOWARDS QUALITY USE OF MEDICINE AMONG UNDERGRADUATE STUDENTS." Malaysian Journal of Public Health Medicine 20, no. 3 (December 31, 2020): 49–56. http://dx.doi.org/10.37268/mjphm/vol.20/no.3/art.687.

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Quality use of medicine is crucial not only to optimize health resources, but to safeguard consumers from unsafe use of medicine. Knowing Your Medicine (KYM) Campaign was launched by the Ministry of Health (MOH) Malaysia as an initiative to raise awareness to consumers on quality use of medicines in ensuring wise, safe and effective use of medicines. Materials of the campaign which is the KYM Module, is integrated in one of the elective course in UKM which is offered to undergraduate students across different faculties to increase knowledge and practice on quality use of medicine. This study aims to identify the impact of the KYM Module towards knowledge and practice of the undergraduates enrolled into the course. A one group pre and post-test research design was employed to students using purposive sampling (n=62). The questionnaire consists of three sections which are i) demographic profile, ii) knowledge assessment (14 items) and iii) practice assessment (15 items). Frequency analysis and paired sample T-test were used to measure the impact of the module. Knowledge of the undergraduates increased from fair/good to good/excellent, as knowledge score of 64.5% students reached excellent post-test compared to 35.5% pre-test. In terms of practice, a paired T-test analysis shows that there is a statistically significant increase in practice scores from pre-test (M = 4.2, SD = .472) to post-test (M = 4.57, SD = .341), t (61) =-3.859, p<.05 (two tailed). In summary, both knowledge and practice improved significantly among undergraduates after completing the module. This research serves as an important data to support the effectiveness of MOH initiative in disseminating important information regarding quality use of medicine to the public.

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Mustafa Din, Wardah, and Noor Ashikeen Zainal Abidin. "KNOWLEDGE AND PRACTICE TOWARDS QUALITY USE OF MEDICINE AMONG UNDERGRADUATE STUDENTS." Malaysian Journal of Public Health Medicine 20, no. 3 (December 31, 2020): 49–56. http://dx.doi.org/10.37268/mjphm/vol.20/no.3/art.687.

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Quality use of medicine is crucial not only to optimize health resources, but to safeguard consumers from unsafe use of medicine. Knowing Your Medicine (KYM) Campaign was launched by the Ministry of Health (MOH) Malaysia as an initiative to raise awareness to consumers on quality use of medicines in ensuring wise, safe and effective use of medicines. Materials of the campaign which is the KYM Module, is integrated in one of the elective course in UKM which is offered to undergraduate students across different faculties to increase knowledge and practice on quality use of medicine. This study aims to identify the impact of the KYM Module towards knowledge and practice of the undergraduates enrolled into the course. A one group pre and post-test research design was employed to students using purposive sampling (n=62). The questionnaire consists of three sections which are i) demographic profile, ii) knowledge assessment (14 items) and iii) practice assessment (15 items). Frequency analysis and paired sample T-test were used to measure the impact of the module. Knowledge of the undergraduates increased from fair/good to good/excellent, as knowledge score of 64.5% students reached excellent post-test compared to 35.5% pre-test. In terms of practice, a paired T-test analysis shows that there is a statistically significant increase in practice scores from pre-test (M = 4.2, SD = .472) to post-test (M = 4.57, SD = .341), t (61) =-3.859, p<.05 (two tailed). In summary, both knowledge and practice improved significantly among undergraduates after completing the module. This research serves as an important data to support the effectiveness of MOH initiative in disseminating important information regarding quality use of medicine to the public.

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Yuslianti, Euis Reni, Boy M. Bachtiar, Dewi Fatma Suniarti, and Afifah B. Sutjiatmo. "NATURAL PRODUCTS PHARMACEUTICAL STANDARDIZATION TOWARDS PHYTOPHARMACA FOR INDONESIAN TRADITIONAL MEDICINE DEVELOPMENT." Dentika Dental Journal 19, no. 2 (December 12, 2016): 179–85. http://dx.doi.org/10.32734/dentika.v19i2.463.

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There is a tendency back to nature treatment in Indonesian community because modern/synthetic medicines is expensive and have a various alarming side effects. That is why natural products medicine becomes more popular, aside from mass media promotions. Researches on natural products such as herbal medicine increases along with the desire to get phytofarmaca that can compete with modern medicines. The aims of this literature review are to discuss and provides information on pharmaceutical standardization of natural products toward phytopharmaca for developing Indonesian traditional medicine. Pharmaceutical standardization will strengthen the basic of pharmaceutical science in producing safe, efficacy, and qualify traditional medicine products. The pharmaceutical standardization consists of standardizing simplicial quality, safety, efficacy, and stable formulation of medicines for use in health services.

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Mant, Andrea. "Quality use of medicines: ten years down the track." Australian Prescriber 25, no. 5 (October 1, 2001): 106–7. http://dx.doi.org/10.18773/austprescr.2001.130.

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Hobbs, Mike. "Quality use of medicines - prescribing for manufacturers or patients?" Australian Prescriber 27, no. 6 (December 1, 2004): 138–41. http://dx.doi.org/10.18773/austprescr.2004.113.

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Gould-Hurst, Peter. "Letters to the Editor: Quality use of generic medicines." Australian Prescriber 28, no. 2 (April 1, 2005): 29–33. http://dx.doi.org/10.18773/austprescr.2005.023.

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Smith, Anthony. "Quality use of medicines – are we nearly there yet?" Australian Prescriber 35, no. 6 (December 1, 2012): 174–75. http://dx.doi.org/10.18773/austprescr.2012.077.

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Pinkerton, Eve, Phillip Good, Korana Kindl, Russell Richard, Amanda Fischer, and Janet R. Hardy. "Quality use of medicines: Oral corticosteroids in advanced cancer." Palliative Medicine 33, no. 10 (August 5, 2019): 1325–26. http://dx.doi.org/10.1177/0269216319866647.

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Waller, Steve. "Reducing medication‐related harm through Quality Use of Medicines." Journal of Pharmacy Practice and Research 50, no. 5 (October 2020): 374–76. http://dx.doi.org/10.1002/jppr.1692.

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Tasker, Judith, Rob Wiseman, Patrick Bolton, and Steven Tipper. "Collaborating to manage polypharmacy." Australian Health Review 24, no. 3 (2001): 80. http://dx.doi.org/10.1071/ah010080.

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DiNCQUMGP (Divisions National Consortium for the Quality Use of Medicines in General Practice) reports on acollaboration between doctors, pharmaceutical companies, government agencies, and medicine users to managepolypharmacy (prescribing multiple medicines to a patient) amongst older people.We have reported the outcomes of our collaboration (improving the Quality Use of Medicines) elsewhere. Here wediscuss how we worked together, opened up new opportunities, and learned from one another. The first part of thisarticle outlines a constructive new way of thinking about collaborating, that we argue is fundamentally different fromcurrent approaches. The second part describes what we did in the words of those involved.

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Camargo, Ely Eduardo Saranz, Mary Anne Medeiros Bandeira, and Anselmo Gomes de Oliveira. "Diagnosis of Public Programs focused on Herbal Medicines in Brazil." Natural Product Communications 6, no. 7 (July 2011): 1934578X1100600. http://dx.doi.org/10.1177/1934578x1100600720.

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The present study is aimed to diagnose the current public programs focused on herbal medicines in Brazil by means of in loco visits to 10 programs selected by means of questionnaires sent to 124 municipalities that count on herbal medicine services. The main purpose of the implementation of program programs is related to the development of medicinal herbs. 70% of them are intended for the production of herbal medicines and 50% are aimed to ensure the access of the population to medicinal plants and or herbal medicines. The initiative of the implementation of these programs was related to the managers (60%). The difficulties in this implementation were due to the lack of funding (100%) of the programs. In 60% of the programs, the physicians did not adhere to herbal medicine services due to the lack of knowledge of the subject. Training courses were proposed (80%) to increase the adhesion of prescribers to the system. Some municipalities use information obtained from patients to assess the therapeutic efficiency of medicinal plants and herbal medicines. Of the programs underway, cultivation of medicinal plants was observed in 90% and 78% of them adopt quality control. In most programs, this control is not performed in accordance with the legal requirements. The programs focused on medicinal plants and herbal medicines implemented in Brazil face some chronic problems of infrastructure, management, operational capacity and self-sustainability, which can be directly related to the absence of a national policy on medicinal plants and herbal medicines.

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Burylo, Y. P. "Novelties of the legislation on veterinary medicinal products." Uzhhorod National University Herald. Series: Law 66 (November 29, 2021): 142–46. http://dx.doi.org/10.24144/2307-3322.2021.66.24.

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The article is devoted to the analysis of the latest innovations in the legislation on veterinary medicine, namely the regulation of the production, distribution and use of veterinary medicines. The adoption of the new Law of Ukraine “On Veterinary Medicine” is caused by the need to approximate the relevant national legislation with the legislation of the European Union to fulfill Ukraine’s international obligations under the Association Agreement. This law reflects the latest trends in the development of legislation on veterinary medicinal products in the European Union. The article pays attention to the strengthening of state regulation of production and distribution of veterinary medicines, in particular the introduction of licensing of imports, wholesale and retail sales of these medicines in Ukraine, due to the need to combat counterfeiting and veterinary medicinal products of dubious quality. It is also noted that the changes in the procedure of state registration of veterinary medicines provided by this law will on the one hand reduce the administrative burden on business due to the transition to indefinite state registration of veterinary drugs, and on the other hand new requirements for the registration dossier will improve the safety, quality and efficacy of veterinary medicinal products. New requirements for the use of antibiotics are analyzed. Attention is drawn to the fact that along with the regulation of the use of antibiotics in animal husbandry, it is also necessary to regulate in more detail the issues of control of the circulation of active substances (active pharmaceutical ingredients). The article also deals with the mechanism of veterinary pharmacovigilance, which is new for Ukraine. At the same time, it is necessary to study the practical experience of implementing the European model of pharmaco to improve the relevant legislation in Ukraine.

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Carreón, Yojana J. P., Orlando Díaz-Hernández, Gerardo J. Escalera Santos, Ivan Cipriano-Urbano, Francisco J. Solorio-Ordaz, Jorge González-Gutiérrez, and Roberto Zenit. "Texture Analysis of Dried Droplets for the Quality Control of Medicines." Sensors 21, no. 12 (June 11, 2021): 4048. http://dx.doi.org/10.3390/s21124048.

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The quality control of medicines guarantees the effectiveness of treatments for diseases. We explore the use of texture analysis of patterns in dried droplets as a tool to readily detect both impurities and changes in drug concentration. Four types of medicines associated with different routes of administration were analyzed: Methotrexate, Ciprofloxacin, Clonazepam, and Budesonide. We use NaCl and a hot substrate at 63 ∘C to promote aggregate formation and to reduce droplet drying time. Depending on the medicine, optical microscopy reveals different complex aggregates such as circular to oval splatters, fern-like islands, crown shapes, crown needle-like and bump-like patterns as well as dendritic branched and star-like crystals. We use some physical features of the stains (as the stain diameter and superficial area) and gray level co-occurrence matrix (GLCM) to characterize patterns of dried droplets. Finally, we show that structural analysis of stains can achieve 95% accuracy in identifying medicines with 30% water dilution, while it achieves 99% accuracy in detecting drugs with 10% other substances.

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Gorman, Ashleigh, Marina Odalović, Philip McCallion, Éilish Burke, Malcolm MacLachlan, Mary McCarron, Martin Henman, et al. "Examining Quality, Use and Impact of Psychotropic (Use) in older adults with intellectual disabilities (EQUIP): study protocol." HRB Open Research 5 (November 9, 2022): 71. http://dx.doi.org/10.12688/hrbopenres.13645.1.

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Widespread, and sometimes inappropriate use of psychotropics in adults with intellectual disability has been an international concern. These medicines have been used to treat mental health conditions, but also, controversially, some types of behaviours not necessarily associated with the diagnosis or in the absence of a relevant diagnosis. Results from the Intellectual Disability Supplement to the Irish Longitudinal Study on Ageing (IDS-TILDA) study of older adults with intellectual disability in Ireland revealed that 60% were taking psychotropics in 2010. In the intervening decade changes in regulations, policy, and increased decongregation of people with intellectual disability have taken place likely influencing the use of psychotropics. The HSE National Clinical Programme for People with Disability (NCPDD) established in the 2020 has medicines optimisation as a key priority. Existing multi-wave data from the IDS-TILDA study and the HSE national prescribing database offers an opportunity to better understand psychotropic use and prescribing patterns. This is a novel collaboration on lived experience, research, practice and policy. The aim of this research is to examine the quality and trends of psychotropic use of older adults with intellectual disability over a ten-year period in Ireland to evaluate the effects of and to inform both practice and policy to optimise medicines use and health outcomes. Health and medication data from ten years (four waves) of the IDS-TILDA study and corresponding medicines data from the HSE-PCRS prescribing database are available. Descriptive and longitudinal analysis will examine association between long-term psychotropic use, changes in trends of use, and the impact of decongregation on medicines use. This research will inform the development of national guidance on medicines optimisation for older people with intellectual disability and has the potential to change prescribing practices and improve health and wellbeing for older people with intellectual disability.

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O’Dwyer, Maire, Philip McCallion, Mary McCarron, and Martin Henman. "Medication use and potentially inappropriate prescribing in older adults with intellectual disabilities: a neglected area of research." Therapeutic Advances in Drug Safety 9, no. 9 (June 20, 2018): 535–57. http://dx.doi.org/10.1177/2042098618782785.

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It is known that for all adults, prevalence of potentially inappropriate prescribing (PIP) and polypharmacy increases with advancing age and morbidity. This has been associated with adverse drug reactions and poor outcomes. As a result, screening tools have been developed to identify PIP and to improve prescribing and health outcomes. A growing body of evidence supports the fact that there are even greater concerns among older adults with intellectual disability (ID) who are living longer than before but still have premature mortality and poorer health outcomes compared with the general population. They have different patterns of multimorbidity, with higher rates of epilepsy and mental health conditions. Polypharmacy is prevalent and some prescribing practices may be inappropriate. High exposure to anticholinergic and sedative medicines has additional adverse effects on quality of life. There may also be underutilization of clinically needed therapies. There has been substantial controversy internationally relating to extensive use of psychotropic medicines, particularly off-label use for challenging behaviours. Despite the mounting evidence and concerns about the impact of PIP on quality of life, health and safety for people with ID, appropriate methods to measure PIP are lacking, which represents an important gap in the research literature. Differences in morbidity and medicines use patterns in this population mean instruments used to identify inappropriate medicines in the older population are not suitable. In this perspective article we outline the specific health and medicinal needs for people with ID, the prevalence of polypharmacy and presentation of chronic health conditions in older adults with ID. We provide an overview of the psychotropic medicine classes most frequently used in people with ID which carry substantial risk. We highlight studies to date that have attempted to assess PIP and present research priorities to improve prescribing, health outcomes and quality of life for people with ID.

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Ahmad, Israr, Satyam Sharma, Deepak kr Chaurasia, and Dr Tarkeshwar P. Shukla. "Quality Control and Evaluation of Herbal Product." International Journal for Research in Applied Science and Engineering Technology 11, no. 1 (January 31, 2023): 770–76. http://dx.doi.org/10.22214/ijraset.2023.48683.

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Abstract: Standardization of herbal formulation is important in order to assess of quality drug. The quality of herbal drug is the considerate all the factor which contribute directly or indirectly to the safety, effectiveness of the product Medicinal plant have been used to improve human health , increasing popularity global as drug , complementary and alternative medicines, food supplement, cosmetic as medical devices. The complexity of herbs and extracts supplied to such a wide range of markets and in different requlatory environment, raise major quality issues, increasing the need for appropriate analytical method for their identification, standardization &also for the detection of adulterants and contamination. Major limitation factors, such as herbal product naming, sampling and sample preparation are also discussed. The use of products of natural origin has remarkably increased in the global market, because of consumer becoming more health-conscious herbal medicines are considered safe by consumers and these product are generally less expensive than allopathic medicines.

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Patel, M., P. Bessong, and H. Liu. "Traditional Medicines, HIV, and Related Infections." Advances in Dental Research 23, no. 1 (March 25, 2011): 159–64. http://dx.doi.org/10.1177/0022034511400077.

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Traditional medicines are an integral part of health care worldwide, even though their efficacy has not been scientifically proven. HIV-infected individuals may use them singularly or in combination with conventional medicines. Many in vitro studies have proven the anti-HIV, anti- Candida, and anti–herpes simplex virus potential of traditional plants and identified some of the mechanisms of action. Very few in vivo studies are available that involve a small number of participants and show controversial results. In addition, knowledge is limited of the role of traditional medicines in the enhancement of the immune system. The use of traditional medicines with antiretroviral drugs (ARVs) has created a problem because drug interactions compromise the efficacy of ARVs. Several currently popular plants have been studied in the laboratory for their interaction with ARVs, with disadvantageous results. Unfortunately, no clinical trials are available. The science of traditional medicines is relatively new and is at present being modernized worldwide. However, there are still ethical issues regarding traditional medicines that need to be addressed—for example, regulations regarding quality control and standardization of medicines, regulation and education of healers who deliver these medicines, and unregulated clinical trials. The workshop addressed the following questions about traditional medicine and their use in HIV infection: What are the mechanisms of action of anti-HIV traditional medicines? Should traditional medicines be used in conjunction with ARV? Do traditional medicines enhance the immune system? Should medicinal plants be used for the control of oral infections associated with HIV? What are the ethical issues surrounding the use of traditional medicines for the treatment of HIV and associated infections?

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Karki, Khem Bahadur, Neelam Dhakal, Baburam Humagain, Arpana Pandit, Trishna Acharya, and Pradip Gyanwali. "Quality of Drug in Health Facilities: A Cross-sectional Study." Journal of Nepal Health Research Council 18, no. 4 (January 21, 2021): 644–48. http://dx.doi.org/10.33314/jnhrc.v18i4.2896.

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Background: Poor quality drugs result minor to detrimental effect on human health. The drug should be of standard quality and should be used appropriately in order to meet its therapeutic efficacy. This study aims to assess the quality of drug in Nepal. Methods: A cross sectional study was conducted in randomly selected 88 health facilities in Nepal from 10th April to 30th June 2016. Selective medicines were collected from both private licensed pharmacies and selected public health facilities. Face to face interview with health facility in-charge of selected health facilities was carried out along with the direct observation of the medicine storage room. The collected medicine samples were dispatched to two laboratories for in-vitro analysis. The labels of the collected medicine were analyzed. The obtained data were entered in Epidata version 3.1, cleaned in Microsoft excel 2007 and analyzed in SPSS version 20.Results: Out of 172 brands, nine brands of medicines were found substandard. Information regarding storage conditions, direction for use and category of the drug were lacking in the label of some brands of medicines. Some selected health facilities were found not meeting major requirements for drug storage: protection from sunlight, moisture, heat, well ventilation and proper sanitation.Conclusions: Few drugs were found to be substandard in Nepalese market from both public and private sectors. Adequate labeling and proper storage condition of medicines in health facilities were lacking.Keywords: Drug quality; private pharmacies; public health facilities; substandard drugs.

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McManus, Dominic, and Bernard David Naughton. "A systematic review of substandard, falsified, unlicensed and unregistered medicine sampling studies: a focus on context, prevalence, and quality." BMJ Global Health 5, no. 8 (August 2020): e002393. http://dx.doi.org/10.1136/bmjgh-2020-002393.

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Substandard and falsified (SF) medicines are a global issue contributing to antimicrobial resistance and causing economic and humanitarian harm. To direct law enforcement efficiently, halt the spread of SF medicines and antimicrobial resistance, academics, NGOs and government organisations use medicine quality sampling studies to estimate the prevalence of the problem. A systematic review of medicine quality studies was conducted to estimate how the methodological quality of these studies and SF prevalence has changed between 2013 and 2018. We also aimed to critique medicine sampling study methodologies, and the systematic review process which generates prevalence estimates. Based on 33 studies, the overall estimated median (Q1–Q3) prevalence of SF medicines appears to have remained high at 25% (7.7%–34%) compared with 28.5% in 2013. Furthermore, the methodological quality of prevalence studies has improved over the last 25 years. Definitive conclusions regarding the prevalence of SF medicines cannot be drawn due to the variability in sample sizes, consistency of design methods, and a lack of information concerning contextual factors affecting medicine quality studies. We contend that studies which present cumulative average prevalence figures are useful in a broad sense but could be improved to create more reliable estimates. We propose that medicine quality studies record the context of the study environment to allow systematic reviewers to compare like with like. Although, the academic rigour of medicine quality studies is improving, medicine sampling study limitations still exist. These limitations inhibit the accurate estimation of SF medicine prevalence which is needed to support detailed policy changes.

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Tereshina, N. S., M. N. Lyakina, and O. A. Naumova. "Sea Water-Based Medicines: Manufacturing Technology and Standardisation." Bulletin of the Scientific Centre for Expert Evaluation of Medicinal Products 10, no. 4 (December 11, 2020): 228–34. http://dx.doi.org/10.30895/1991-2919-2020-10-4-228-235.

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Sea water and sea salt obtained from it are widely used as substances in the production of medicinal products. Complex chemical composition of sea water which contains various salts, calls for the development of a common quality standard for sea water-based medicines. The aim of the study was to analyse and summarise available data on the sources of sea water-based medicines, and on the current test methods, as well as to develop a unified approach to quality control. The paper summarises information on the use of sea water for medical purposes. It presents comparative data on the chemical composition of sea water obtained from different sources, manufacturing technologies of sea water-based medicines, and composition of medicines produced from sea water or sea salt. The paper summarises data on the use of sea water for the production of various dosage forms: drops, sprays, aerosols. The study revealed qualitative and quantitative differences in the content of major cations and anions in drug products. The authors analysed the use of various chemical and physico-chemical test methods for qualitative and quantitative characterisation of medicines. It was concluded that there is a need to harmonise quality control methods for sea water-based medicines.

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Mansfield, Peter. "Can pharmaceutical companies contribute to the quality use of medicines?" Australian Prescriber 33, no. 4 (August 1, 2010): 98–99. http://dx.doi.org/10.18773/austprescr.2010.049.

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Journal articles on the topic 'Quality use of medicines'

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