Log in

Relevant bibliographies by topics / Pyrimidinyl / Journal articles

To see the other types of publications on this topic, follow the link: Pyrimidinyl.

Journal articles on the topic 'Pyrimidinyl'

Author: Grafiati

Published: 4 June 2021

Last updated: 9 February 2022

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'Pyrimidinyl.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Jiang, Duo Hua, and Gang Liu. "Synthesis and Properties Study of 1-(2,4-Dimethoxyl-5-Pyrimidinyl)-2-[2-Methyl-5-(3-Cyano)-3-Thienyl]Perfluorocyclopentene." Applied Mechanics and Materials 662 (October 2014): 91–94. http://dx.doi.org/10.4028/www.scientific.net/amm.662.91.

Full text

Abstract:

A novel photochromic diarylethene bearing a pyrimidine moiety, 1-(2,4-dimethoxyl-5-pyrimidinyl)-2-[2-methyl-5-(3-cyano)-3-thieny-l] perfluorocyclopentene has been synthesized. Its properties, including photochromic behavior and fluorescent properties, have been investigated. The compound exhibited remarkable photochromism, changing from colorless to blue after irradiation with UV light. The results indicated that the pyrimidine moiety played a very important role during the process of photoisomerization reactions.

APA, Harvard, Vancouver, ISO, and other styles

2

Kurth, Mark, Wonken Choung, Beth Lorsbach, Thomas Sparks, and James Ruiz. "4-(Isoxazol-3-yl)pyrimidines from Pyrimidinyl Nitrile Oxides." Synlett 2008, no. 19 (November 12, 2008): 3036–40. http://dx.doi.org/10.1055/s-0028-1087346.

Full text

APA, Harvard, Vancouver, ISO, and other styles

3

Hurst, DT, AD Stacey, M. Nethercleft, A. Rahim, and MR Harnden. "The Synthesis of Some Pyrimidinyl and Thiazolyl Ureas and Thioureas and Some Related Compounds." Australian Journal of Chemistry 41, no. 8 (1988): 1221. http://dx.doi.org/10.1071/ch9881221.

Full text

Abstract:

Some pyrimidin-2- and pyrimidin-4-amines were treated with isocyanates and isothiocyanates to give the corresponding disubstituted ureas or thioureas . A pyrimidin-2-amine is more reactive than a pyrimidin-4- amine in these reactions. 2-Aminothiazoles and thiazolinones also react to give the disubstituted ureas or thioureas . The use of ethoxycarbonyl or benzoyl isothiocyanate or isocyanate gives products which are readily hydrolysed to the pyrimidinyl or thiazolyureas or thioureas but with concomitant hydrolysis and decarboxylation of an ethoxycarbonyl substituent . The use of chlorosulfonyl or trimethylsilyl isocyanate gives the urea derivative without isolation of the intermediate disubstituted urea. Some related compounds were also synthesized.

APA, Harvard, Vancouver, ISO, and other styles

4

Sharma, Vijay Kumar, Anup Barde, and Sunita Rattan. "Design, Synthesis and Characterization of Pyrimidine based Thiazolidinedione Derivatives." Asian Journal of Chemistry 32, no. 5 (2020): 1101–8. http://dx.doi.org/10.14233/ajchem.2020.22565.

Full text

Abstract:

Novel thiazolidine-2,4-dione (TZD) based pyrimidine derivatives have been synthesized by Knoevenagel condensation reaction between thiazolidine-2,4-dione and amino pyrimidinyl aliphatic aldehydes followed by heterogeneous metal reduction. Synthetic strategy involved nucleophillic substitution of hydroxyl protected six membered aliphatic chain on 4,6-dichloropyrimidine followed by Suzuki coupling. This approach is regioselective, efficient and versatile for synthesis of such analogs

APA, Harvard, Vancouver, ISO, and other styles

5

Liu, Jing Jing, Hong Jing Jia, and Shou Zhi Pu. "Synthesis and Properties Study of 1-(2,4-dimethoxyl-5-pyrimidinyl)-2-[2-methyl-5-(9-phenanthrene)-3-thienyl] perfluorocyclopentene." Advanced Materials Research 1003 (July 2014): 31–34. http://dx.doi.org/10.4028/www.scientific.net/amr.1003.31.

Full text

Abstract:

A novel photochromic diarylethene bearing a pyrimidine moiety, 1-(2,4-dimethoxyl-5-pyrimidinyl)-2-[2-methyl-5-(9-phenanthrene)-3-thienyl] perfluorocyclopentene has been synthesized. Its properties, including photochromic behavior and fluorescent properties, have been investigated. The compound exhibited remarkable photochromism, changing from colorless to red after irradiation with UV light in solution. The fluorescence had a remarkable initial increase with subsequent dramatic decrease with increasing concentration. The results indicated that the pyrimidine moiety played a very important role during the process of photoisomerization reactions.

APA, Harvard, Vancouver, ISO, and other styles

6

Liu, Jing Jing, Hong Jing Jia, and Shou Zhi Pu. "Synthesis and Properties Study of 1-(2,4-dimethoxyl-5-pyrimidinyl)-2-[2-methyl-5-(4-n-pentylbenzene)-3-thienyl] Perfluorocyclopentene." Advanced Materials Research 952 (May 2014): 75–78. http://dx.doi.org/10.4028/www.scientific.net/amr.952.75.

Full text

Abstract:

A novel photochromic diarylethene based on a six-membered pyrimidine moiety 1-(2,4-dimethoxyl-5-pyrimidinyl)-2-[2-methyl-5-(4-n-pentylbenzene)-3-thienyl] perfluorocyclopent-ene has been synthesized. Its properties, including photochromic behavior and fluorescent properties, have been investigated. The compounds exhibited remarkable photochromism, changing from colorless to red after irradiation with UV light both in solution and in PMMA film. The fluorescence had a remarkable initial increase with subsequent dramatic decrease with increasing concentration. The results indicated that the pyrimidine moiety played a very important role during the process of photoisomerization reactions.

APA, Harvard, Vancouver, ISO, and other styles

7

Brough, Peter, Jacques Pécaut, André Rassat, and Paul Rey. "Pyrimidinyl Nitronyl Nitroxides." Chemistry - A European Journal 12, no. 19 (June 23, 2006): 5134–41. http://dx.doi.org/10.1002/chem.200600061.

Full text

APA, Harvard, Vancouver, ISO, and other styles

8

Wang, Hsiao-Fen, Kuang-Hway Yih, and Gene-Hsiang Lee. "Syntheses, Reactivities, Characterization, and Crystal Structures of Dipalladium Complexes Containing the 1,3-pyrimidinyl Ligand: Structures of [Pd(PPh3)(Br)]2(μ,η2-C4H3N2)2, [Pd(Br)]2(μ,η2-Hdppa)2, and [{Pd(PPh3)(CH3CN)}2(μ,η2-C4H3N2)2][BF4]2." Molecules 25, no. 9 (April 27, 2020): 2035. http://dx.doi.org/10.3390/molecules25092035.

Full text

Abstract:

In a refluxing chloroform solution, the η1-pyrimidinyl {pyrimidinyl = C4H3N2} palladium complex [Pd(PPh3)2(η1-C4H3N2)(Br)], 1 exhibited intermolecular displacement of two triphenylphosphine ligands to form the doubly bridged η2-pyrimidinyl Dipalladium complex [Pd(PPh3)(Br)]2(μ,η2-C4H3N2)2, 3. The treatment of 1 with Hdppa {Hdppa = N,N-bisdiphenyl phosphinoamine} in refluxing dichloromethane yielded the doubly bridged Hdppa dipalladium complex [Pd(Br)]2(μ,η2-Hdppa)2, 4. Complex 1 reacted with the bidentate ligand, NH4S2CNC4H8 and, NaS2COEt, and the tridentate ligand, KTp {Tp = tris(pyrazoyl-1-yl)borate}, to form the η2-dithio η1-pyrimidinyl complex [Pd(PPh3)(η1-C4H3N2)(η2-SS)], (5: SS = S2CNC4H8; 6: SS = S2COEt) and η2-Tp η1-pyrimidinyl complex [Pd(PPh3)(η1-C4H3N2)(η2-Tp)], 7, respectively. Treatment of 1 with AgBF4 in acetonitrile at room temperature resulted in the formation of the doubly bridged η2-pyrimidinyl dipalladium complex [{Pd(PPh3)(CH3CN)}2(μ,η2-C4H3N2)2][BF4]2, 8. All of the complexes were identified using spectroscopic methods, and complexes 3, 4, and 8 were determined using single-crystal X-ray diffraction analyses.

APA, Harvard, Vancouver, ISO, and other styles

9

Voigt, Harry, Dietrich Heydenhauß, Frank Hofmann, and Günter Jaenecke. "Gemischte Pyrimidinyl-azolyl-thioäther." Zeitschrift für Chemie 14, no. 12 (September 1, 2010): 472. http://dx.doi.org/10.1002/zfch.19740141208.

Full text

APA, Harvard, Vancouver, ISO, and other styles

10

Smicius, Romualdas, Virginija Jakubkiene, Milda M. Burbuliene, Aiste Mikalainyte, and Povilas Vainilavicius. "Synthesis of 1-(6-Methyl-2,4-Dioxo-1,2,3,4-Tetrahydro-3-Pyrimidinyl)Acetyl-4-Alkyl(Aryl)Thiosemicarbazides and their Heterocyclisation to 1,2,4-Triazoles and 1,3,4-Thiadiazoles." Journal of Chemical Research 2002, no. 4 (April 2002): 170–72. http://dx.doi.org/10.3184/030823402103171555.

Full text

Abstract:

5-(6-Methyl-2,4-dioxo-1,2,3,4-tetrahydro-3-pyrimidinyl)methyl-1,3,4-oxadiazole-2-thione reacts with amines to give 1-(6-methyl-2,4-dioxo-1,2,3,4-tetrahydro-3-pyrimidinyl)acetyl-4-alkyl(aryl)thiosemicarbazides, which on treatment with base or acid undergo cyclisation to 4-alkyl-1,2,4-triazole-2-thiones or 4-amino-1,3,4-thiadiazoles, respectively.

APA, Harvard, Vancouver, ISO, and other styles

11

van der Westhuyzen, Christiaan W., Richard K. Haynes, Jenny-Lee Panayides, Ian Wiid, and Christopher J. Parkinson. "Anti-Mycobacterial Peroxides: A New Class of Agents for Development Against Tuberculosis." Medicinal Chemistry 16, no. 3 (April 17, 2020): 392–402. http://dx.doi.org/10.2174/1573406415666190430143535.

Full text

Abstract:

Background: With few exceptions, existing tuberculosis drugs were developed many years ago and resistance profiles have emerged. This has created a need for new drugs with discrete modes of action. There is evidence that tuberculosis (like other bacteria) is susceptible to oxidative pressure and this has yet to be properly utilised as a therapeutic approach in a manner similar to that which has proven highly successful in malaria therapy. Objective: To develop an alternative approach to the incorporation of bacterial siderophores that results in the creation of antitubercular peroxidic leads for subsequent development as novel agents against tuberculosis. Methods: Eight novel peroxides were prepared and the antitubercular activity (H37Rv) was compared to existing artemisinin derivatives in vitro. The potential for toxicity was evaluated against the L6 rat skeletal myoblast and HeLa cervical cancer lines in vitro. Results: The addition of a pyrimidinyl residue to an artemisinin or, preferably, a tetraoxane peroxidic structure results in antitubercular activity in vitro. The same effect is not observed in the absence of the pyrimidine or with other heteroaromatic substituents. Conclusion: The incorporation of a pyrimidinyl residue adjacent to the peroxidic function in an organic peroxide results in anti-tubercular activity in an otherwise inactive peroxidic compound. This will be a useful approach for creating oxidative drugs to target tuberculosis.

APA, Harvard, Vancouver, ISO, and other styles

12

Maes, Wouter, Thien H. Ngo, Jeroen Vanderhaeghen, and Wim Dehaen. "meso-Pyrimidinyl-Substituted A2B-Corroles." Organic Letters 9, no. 16 (August 2007): 3165–68. http://dx.doi.org/10.1021/ol071226a.

Full text

APA, Harvard, Vancouver, ISO, and other styles

13

ZHAO, C. X., Z. B. Zhou, H. Y. He, Z. Y. Weng, S. J. Xue, and A. D. Zhang. "ω-hydro-perfluoroalkyl pyrimidinyl nitroxides." Research on Chemical Intermediates 21, no. 1 (January 1995): 1–6. http://dx.doi.org/10.1163/156856795x00017.

Full text

APA, Harvard, Vancouver, ISO, and other styles

14

Wan, De Cheng, Hong Ting Pu, and Gen Jin Yang. "Homopolymerization of N-pyrimidinyl acrylamide." Chinese Chemical Letters 18, no. 9 (September 2007): 1141–44. http://dx.doi.org/10.1016/j.cclet.2007.07.037.

Full text

APA, Harvard, Vancouver, ISO, and other styles

15

Nwachukwu, Chideraa I., Leanna J. Patton, Nathan P. Bowling, and Eric Bosch. "Ditopic halogen bonding with bipyrimidines and activated pyrimidines." Acta Crystallographica Section C Structural Chemistry 76, no. 5 (April 20, 2020): 458–67. http://dx.doi.org/10.1107/s2053229620005082.

Full text

Abstract:

The potential of pyrimidines to serve as ditopic halogen-bond acceptors is explored. The halogen-bonded cocrystals formed from solutions of either 5,5′-bipyrimidine (C8H6N4) or 1,2-bis(pyrimidin-5-yl)ethyne (C10H6N4) and 2 molar equivalents of 1,3-diiodotetrafluorobenzene (C6F4I2) have a 1:1 composition. Each pyrimidine moiety acts as a single halogen-bond acceptor and the bipyrimidines act as ditopic halogen-bond acceptors. In contrast, the activated pyrimidines 2- and 5-{[4-(dimethylamino)phenyl]ethynyl}pyrimidine (C14H13N3) are ditopic halogen-bond acceptors, and 1:1 halogen-bonded cocrystals are formed from 1:1 mixtures of each of the activated pyrimidines and either 1,2- or 1,3-diiodotetrafluorobenzene. A 1:1 cocrystal was also formed between 2-{[4-(dimethylamino)phenyl]ethynyl}pyrimidine and 1,4-diiodotetrafluorobenzene, while a 2:1 cocrystal was formed between 5-{[4-(dimethylamino)phenyl]ethynyl}pyrimidine and 1,4-diiodotetrafluorobenzene.

APA, Harvard, Vancouver, ISO, and other styles

16

Feil, Vernon J., Gaylord D. Paulson, and Anders L. Lund. "Diazomethane Derivatization of Sulfamethazine: Formation of Isomeric Products." Journal of AOAC INTERNATIONAL 72, no. 3 (May 1, 1989): 515–16. http://dx.doi.org/10.1093/jaoac/72.3.515.

Full text

Abstract:

Abstract Reaction of 4-amino-N-(4,6-dimethyl-2-pyrimidinyl)benzenesulfonamide (sulfamethazine) with diazomethane yields not only 4-amino- N-(4,6-dimethyl-2-pyrimidinyl)-iV-methylbenzenesulfonamide but also 2-(4-aminobenzenesulfonimido)-1,4,6-trimethyl-1,2-dihydropyrimidine. Yields of the latter compound are highly variable and the compound does not show a response to gas chromatography. Thus, results of gas chromatographic determinations of residues of some sulfa drugs in edible meat tissues may be erroneous when diazomethane derivatization is used.

APA, Harvard, Vancouver, ISO, and other styles

17

Jang, Miyoung, Youri Oh, Hyunwook Cho, Songyi Yang, Hyungwoo Moon, Daseul Im, and Jung-Mi Hah. "Discovery of 1-Pyrimidinyl-2-Aryl-4,6-Dihydropyrrolo [3,4-d]Imidazole-5(1H)-Carboxamide as a Novel JNK Inhibitor." International Journal of Molecular Sciences 21, no. 5 (March 2, 2020): 1698. http://dx.doi.org/10.3390/ijms21051698.

Full text

Abstract:

We designed and synthesized 1-pyrimidinyl-2-aryl-4, 6-dihydropyrrolo [3,4-d] imidazole-5(1H)-carboxamide derivatives as selective inhibitors of c-Jun-N-terminal Kinase 3 (JNK3), a target for the treatment of neurodegenerative diseases. Based on the compounds found in previous studies, a novel scaffold was designed to improve pharmacokinetic characters and activity, and compound 18a, (R)-1-(2-((1-(cyclopropanecarbonyl)pyrrolidin-3-yl)amino)pyrimidin-4-yl)-2-(3,4-dichlorophenyl)-4,6-dihydro pyrrolo [3,4-d]imidazole-5(1H)-carboxamide, showed the highest IC50 value of 2.69 nM. Kinase profiling results also showed high selectivity for JNK3 among 38 kinases, having mild activity against JNK2, RIPK3, and GSK3β, which also known to involve in neuronal apoptosis.

APA, Harvard, Vancouver, ISO, and other styles

18

SHIMIZU, Tsutomu. "Action Mechanism of Pyrimidinyl Carboxy Herbicides." Journal of Pesticide Science 22, no. 3 (1997): 245–56. http://dx.doi.org/10.1584/jpestics.22.245.

Full text

APA, Harvard, Vancouver, ISO, and other styles

19

V. Tverdokhlebov, Anton, Igor Yu. Nestorak, Andrey A. Tolmachev, and Yulian M. Volovenko. "Synthesis of 3-(Pyrimidinyl)pyrrole Derivatives." HETEROCYCLES 81, no. 3 (2010): 611. http://dx.doi.org/10.3987/com-09-11881.

Full text

APA, Harvard, Vancouver, ISO, and other styles

20

Caruso, F., and M. Rossi. "Bis(4-chlorophenyl)(5-pyrimidinyl)methanol." Acta Crystallographica Section C Crystal Structure Communications 54, no. 11 (November 15, 1998): 1668–70. http://dx.doi.org/10.1107/s0108270198003485.

Full text

APA, Harvard, Vancouver, ISO, and other styles

21

Brown, C. J., D. S. Cook, and L. Sengier. "Diamminebis[N'-(2-pyrimidinyl)sulfanilamido]copper." Acta Crystallographica Section C Crystal Structure Communications 43, no. 12 (December 15, 1987): 2332–34. http://dx.doi.org/10.1107/s0108270187087869.

Full text

APA, Harvard, Vancouver, ISO, and other styles

22

Kokila, M. K., Puttaraja Puttaraja, M. V. Kulkarni, and S. Thampi. "4-Amino-N-(2-pyrimidinyl)benzenesulfonamide." Acta Crystallographica Section C Crystal Structure Communications 51, no. 2 (February 15, 1995): 333–36. http://dx.doi.org/10.1107/s0108270193014180.

Full text

APA, Harvard, Vancouver, ISO, and other styles

23

Abdelhamid, Abdou O., Zeineb H. Ismail, and Anhar Abdel-Aziem. "Reactions with Hydrazonoyl Halides 601: Synthesis of Thieno[2′,3′:4,5] Pyrimidino[1,2-b][1,2,4,5]tetrazines, [1]benzothieno[2′,3′:4,5]pyrimidino [1,2-b][1,2,4,5]tetrazines, Pyrazolo[3′,4′:4,5]pyrimidino[1,2-b] [1,2,4,5]tetrazines and Pyrazolo[3,4-d]pyridazines." Journal of Chemical Research 2007, no. 10 (October 2007): 609–16. http://dx.doi.org/10.3184/030823407x256118.

Full text

Abstract:

Thieno[2′,3′:4,5]pyrimidino[1,2- b][1,2,4,5]tetrazine, [1]benzothieno-[2′,3′:4,5]pyrimidino[1,2- b][1,2,4,5]tetrazine, pyrazolo [3′,4′:4,5]pyrimidino[1,2- b][1,2,4,5]tetrazine, triazolo[4,3- a]pyrimidin-5(1 H)-one, 1-{[2-(1-benzofuran-2-yl)-5-phenyl-4,5-dihydro-1 H-pyrazol-1-yl]-4-substituted-1,3-thiazol-5-yl}-2-phenyldiazene, 3-acyl-4-(1-benzofuran-2-ylcarbonyl) pyrazole and pyrazolo[3,4- d]pyridazine derivatives could be obtained via reactions of hydrazonoyl halides with the appropriate pyrimidine-2-thione, 3-amino-5,6-dimethyl-2-sulfanylthieno[2,3- d]pyrimidin-4(3 H)-one, 5-amino-6-mercapto-1-phenyl-1,5-dihydropyrazolo[3,4- d]pyrimidin-4-one and 1-(benzofuran-2-yl)-3-(dimethylamino)prop-2-en-1-one. Structures of the products have been determined by elemental analyses, spectral data studies and alternative synthesis whenever possible.

APA, Harvard, Vancouver, ISO, and other styles

24

Borrell, José I., Jordi Teixidó, Blanca Martínez-Teipel, Blanca Serra, Josep Lluís Matallana, Marta Costa, and Xavier Batllori. "An Unequivocal Synthesis of 4-Amino-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-2,7-diones and 2-Amino-3,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-4,7-diones." Collection of Czechoslovak Chemical Communications 61, no. 6 (1996): 901–9. http://dx.doi.org/10.1135/cccc19960901.

Full text

Abstract:

An unequivocal set of procedures for the synthesis of 4-amino-1,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-2,7-diones (7) and 2-amino-3,5,6,8-tetrahydropyrido[2,3-d]pyrimidine-4,7-diones (8), in a maximum of four steps from an α,β-unsaturated ester 1, is reported. Thus, the acid hydrolysis of the 2,4-diaminopyrido[2,3-d]pyrimidines 3 yields the 4-amino-2-oxopyrido[2,3-d]pyrimidines 7 while the cyclization of the Michael adducts 9 (formed by reaction of 1 and methyl cyanoacetate) with guanidine affords the corresponding 2-amino-4-oxopyrido[2,3-d]pyrimidines 8. Both isomers were also obtained by hydrolysis of the 4-amino-2-bromo- and 2-amino-4-bromo-5,6-dihydropyrido[2,3-d]pyrimidin-7(8H)-ones 5 and 6, respectively.

APA, Harvard, Vancouver, ISO, and other styles

25

Kang, Gihaeng, Jineun Kim, Eunjin Kwon, and Tae Ho Kim. "Crystal structure of cyclosulfamuron." Acta Crystallographica Section E Crystallographic Communications 71, no. 8 (July 31, 2015): o631—o632. http://dx.doi.org/10.1107/s2056989015014115.

Full text

Abstract:

The title compound (systematic name: 1-{[2-(cyclopropylcarbonyl)anilino]sulfonyl}-3-(4,6-dimethoxypyrimidin-2-yl)urea), C17H19N5O6S, is a pyrimidinylsulfonylurea herbicide. The dihedral angles between the mean planes of the central benzene ring and the cyclopropyl and pyrimidinyl rings are 75.32 (9) and 88.79 (4)°, respectively. The C atoms of the methoxy groups lie almost in the plane of the pyrimidine ring [deviations = 0.043 (2) and 0.028 (2) Å] and intramolecular N—H...N, N—H...O and C—H...O hydrogen bonds all closeS(6) rings. In the crystal, N—H...O and C—H...O hydrogen bonds and weak π–π interactions [centroid–centroid distances = 3.6175 (9) and 3.7068 (9) Å] link adjacent molecules, forming a three-dimensional network.

APA, Harvard, Vancouver, ISO, and other styles

26

Hassanain, Hawazen, E. Stephen Davies, William Lewis, Deborah L. Kays, and Neil R. Champness. "Structural characterization and optical properties of two copper(i)-iodide BODIPY coordination polymers." CrystEngComm 21, no. 31 (2019): 4551–56. http://dx.doi.org/10.1039/c9ce00845d.

Full text

APA, Harvard, Vancouver, ISO, and other styles

27

Walg, Simon P., Alexandra D. Schmidt, Marcus Schmitz, Saeid Farsadpour, Johannes Lang, Mark Niebergall, Yu Sun, Peter W. Roesky, Gereon Niedner-Schatteburg, and Werner R. Thiel. "P,C-bond cleavage in the ligand sphere of a nickel(ii) complex." Dalton Transactions 44, no. 3 (2015): 1317–22. http://dx.doi.org/10.1039/c4dt02158d.

Full text

APA, Harvard, Vancouver, ISO, and other styles

28

Bagheri, Fatemeh, and Abolfazl Olyaei. "A novel approach toward the synthesis of some new tridentate Schiff bases from anil-like compounds." Journal of the Serbian Chemical Society 81, no. 10 (2016): 1111–19. http://dx.doi.org/10.2298/jsc151202064b.

Full text

Abstract:

A novel method was developed for synthesizing a series of new three dentate Schiff base ligands starting from hydroxynaphthalidene pyrimidinyl amines with o-phenylenediamines or o-aminophenol or 2-amino-3-hydroxy-pyri-dine in the presence of formic acid catalyst under solvent-free conditions. In these reactions [1+1] condensation product as half-unit ligand was obtained. Moreover, the reaction of hydroxynaphthalidene pyrimidinyl amines with 3,4-diamino-pyridine and 1,8-naphthalenediamine lead to the formation of C2-naphthylated imidazopyridine and dihydropyrimidine, respectively. The attractive features of this protocol are: use of inexpensive catalyst, operationally simple, short reaction times, easy handling, and good yields.

APA, Harvard, Vancouver, ISO, and other styles

29

Hossain, M. I., and M. M. H. Bhuiyan. "Synthesis and Antimicrobial Activities of Some New Thieno and Furopyrimidine Derivatives." Journal of Scientific Research 1, no. 2 (April 23, 2009): 317–25. http://dx.doi.org/10.3329/jsr.v1i2.2299.

Full text

Abstract:

Fused pyrimidines, 8,9-dimethyl[1,2,4]triazolo[4,3-c]thieno[3,2-e]pyrimidine 5, 3,8,9-trimethyl[1,2,4]triazolo[4,3-c]thieno[3,2-e]pyrimidine 6, 4-benzylidinehydrazono-5,6 dimethylthieno[2,3-d]pyrimidine 7, 4-[4/-hydroxybenzylidine]hydrazono-5,6-dimethylthi-eno[2,3-d]pyrimidine 8, 4-[4/-tolylidin]hydrazono-5,6-dimethylthieno[2,3-d]pyrimidine 9, 4-[4/-nitrobenzylidine]hydrazono-5-ethyl-6-methylthieno[2,3-d]pyrimidine 10 and 4-[4/-chlorobenzylidine]hydrazono-5-ethyl-6-methylthieno[2,3-d]pyrimidine 11 are prepared in good yield by an initial treatment of 2-amino-4,5-dimethylthiophene-3-carbonitrile 1 with formic acid, affording 5,6-dimethylthieno[2,3-d]pyrimidin-4(3H)-one 2, which is chlorinated with thionyl chloride and then hydrazinated with hydrazine hydrate. Finally hydrazino compound 4 is reacted with formic acid, acetic anhydrate, benzaldehyde, p-hydroxybenzaldehyde, p-toluayldehyde, p-nitrobenzaldehyde and p-chlorobenzaldehyde to give thienotriazolopyrimidines 5-6 and thienopyrimidines 7-11 respectively. All the compounds have been screened for their antimicrobial activity. Keywords: Fused pyrimidines; Hydrazino compound; Thienotriazolopyrmidines; Thienopyrimidines; Antimicrobial activity.© 2009 JSR Publications. ISSN: 2070-0237 (Print); 2070-0245 (Online). All rights reserved.DOI: 10.3329/jsr.v1i2.2299

APA, Harvard, Vancouver, ISO, and other styles

30

Plaziak, Adam S., Lech Celewicz, Jaroslaw Spychala, and Krzysztof Golankiewicz. "Mass spectrometry of 4N-pyrimidinyl amino acids." Organic Mass Spectrometry 24, no. 1 (January 1989): 55–58. http://dx.doi.org/10.1002/oms.1210240111.

Full text

APA, Harvard, Vancouver, ISO, and other styles

31

Hoffmann, Siegfried. "N-[2-Methylmercapto-pyrimidinyl-(4)]-aminosäuren [1]." Zeitschrift für Chemie 8, no. 4 (September 2, 2010): 147. http://dx.doi.org/10.1002/zfch.19680080412.

Full text

APA, Harvard, Vancouver, ISO, and other styles

32

Ngo, Thien H., Francesco Nastasi, Fausto Puntoriero, Sebastiano Campagna, Wim Dehaen, and Wouter Maes. "meso-Pyrimidinyl-Substituted A2B- and A3-Corroles." Journal of Organic Chemistry 75, no. 6 (March 19, 2010): 2127–30. http://dx.doi.org/10.1021/jo902709c.

Full text

APA, Harvard, Vancouver, ISO, and other styles

33

Jensen, Gayleen B., Graham Smith, Dalius S. Sagatys, Peter C. Healy, and Jonathan M. White. "Bis(2-pyrimidinyl) disulfide dihydrate: a redetermination." Acta Crystallographica Section E Structure Reports Online 60, no. 12 (November 27, 2004): o2438—o2440. http://dx.doi.org/10.1107/s1600536804029782.

Full text

APA, Harvard, Vancouver, ISO, and other styles

34

Gallagher, P. E., and N. J. Duker. "Detection of UV purine photoproducts in a defined sequence of human DNA." Molecular and Cellular Biology 6, no. 2 (February 1986): 707–9. http://dx.doi.org/10.1128/mcb.6.2.707.

Full text

Abstract:

The UV-irradiated, 3'-end-labeled, 92-base-pair terminus of the human alphoid sequence was incubated with purified endonuclease v. Previously unreported photoproducts were incised at purine loci. These were not pyrimidine photodimers, 6-4'-(pyrimidin-2'-one)-pyrimidines, base loss sites, or ring-opened purines. Therefore, purine-containing photoproducts, possibly dimers, were incised by the enzyme preparation.

APA, Harvard, Vancouver, ISO, and other styles

35

Gallagher, P. E., and N. J. Duker. "Detection of UV purine photoproducts in a defined sequence of human DNA." Molecular and Cellular Biology 6, no. 2 (February 1986): 707–9. http://dx.doi.org/10.1128/mcb.6.2.707-709.1986.

Full text

Abstract:

The UV-irradiated, 3'-end-labeled, 92-base-pair terminus of the human alphoid sequence was incubated with purified endonuclease v. Previously unreported photoproducts were incised at purine loci. These were not pyrimidine photodimers, 6-4'-(pyrimidin-2'-one)-pyrimidines, base loss sites, or ring-opened purines. Therefore, purine-containing photoproducts, possibly dimers, were incised by the enzyme preparation.

APA, Harvard, Vancouver, ISO, and other styles

36

Zhai, Yizhan, Xue Zhang, and Shengming Ma. "Stereoselective rhodium-catalyzed 2-C–H 1,3-dienylation of indoles: dual functions of the directing group." Chemical Science 12, no. 34 (2021): 11330–37. http://dx.doi.org/10.1039/d1sc02167b.

Full text

Abstract:

A rhodium-catalyzed intermolecular highly stereoselective 1,3-dienylation at the 2-position of indoles with non-terminal allenyl carbonates has been developed by using 2-pyrimidinyl or pyridinyl as the directing group.

APA, Harvard, Vancouver, ISO, and other styles

37

Sirakanyan, Spinelli, Geronikaki, Hakobyan, Sahakyan, Arabyan, Zakaryan, et al. "Synthesis, Antitumor Activity, and Docking Analysis of New Pyrido[3’,2’:4,5]furo(thieno)[3,2-d]pyrimidin-8-amines." Molecules 24, no. 21 (October 31, 2019): 3952. http://dx.doi.org/10.3390/molecules24213952.

Full text

Abstract:

Continuing our research in the field of new heterocyclic compounds, herein we report on the synthesis and antitumor activity of new amino derivatives of pyrido[3’,2’:4,5](furo)thieno[3,2-d]pyrimidines as well as of two new heterocyclic systems: furo[2–e]imidazo[1,2-c]pyrimidine and furo[2,3-e]pyrimido[1,2-c]pyrimidine. Thus, by refluxing the 8-chloro derivatives of pyrido[3’,2’:4,5]thieno(furo)[3,2-d]pyrimidines with various amines, the relevant pyrido[3’,2’:4,5]thieno(furo)[3,2-d]pyrimidin-8-amines were obtained. Further, the cyclization of some amines under the action of phosphorus oxychloride led to the formation of new heterorings: imidazo[1,2-c]pyrimidine and pyrimido[1,2-c]pyrimidine. The possible antitumor activity of the newly synthesized compounds was evaluated in vitro. The biological tests evidenced that some of them showed pronounced antitumor activity. A study of the structure–activity relationships revealed that the compound activity depended mostly on the nature of the amine fragments. A docking analysis was also performed for the most active compounds.

APA, Harvard, Vancouver, ISO, and other styles

38

Mekuskiene, Giedrute, Sigitas Tumkevicius, and Povilas Vainilavicius. "5-(4,6-Diphenyl-2-pyrimidinyl)-1,3,4-oxa(thia)diazoles and 1,2,4-triazoles." Journal of Chemical Research 2002, no. 5 (May 2002): 213–15. http://dx.doi.org/10.3184/030823402103171898.

Full text

Abstract:

Synthesis of 5-(4,6-diphenyl-2-pyrimidinyl)-1,3,4-oxa(thia)diazoles and corresponding 1,2,4-triazoles from 4,6-diphenyl-2-pyrimidinecarboxylic acid hydrazide and 1-(4,6-diphenyl-2-pyrimidinylcarbonyl)-4-phenylthiosemi-carbazide is described.

APA, Harvard, Vancouver, ISO, and other styles

39

Rybalova, T. V., V. F. Sedova, Yu V. Gatilov, and O. P. Shkurko. "Synthesis and molecular structure of 2-[2-benzoyl-4-(pyrimidinyl-5)phenyl]-3-phenyl-5-(pyrimidinyl-5)-2H-indazole." Journal of Structural Chemistry 35, no. 6 (November 1994): 932–34. http://dx.doi.org/10.1007/bf02578130.

Full text

APA, Harvard, Vancouver, ISO, and other styles

40

Mishra, Neeraj Kumar, Mijin Jeon, Yongguk Oh, Hyeim Jo, Jihye Park, Sangil Han, Satyasheel Sharma, Sang Hoon Han, Young Hoon Jung, and In Su Kim. "Site-selective Cp*Rh(iii)-catalyzed C–H amination of indolines with anthranils." Organic Chemistry Frontiers 4, no. 2 (2017): 241–49. http://dx.doi.org/10.1039/c6qo00714g.

Full text

Abstract:

The pyrimidinyl-directed C–H functionalization of indolines with anthranils as amination sources under rhodium(iii) catalysis is described to afford a range of C7-aminated indoline derivatives with excellent site-selectivity and functional group compatibility.

APA, Harvard, Vancouver, ISO, and other styles

41

Arukwe, Joseph, Kjell Undheim, Tore Skjetne, and Edward Darzynkiewicz. "Lithiation in the Synthesis of 5-Pyrimidinyl Ketones." Acta Chemica Scandinavica 40b (1986): 588–92. http://dx.doi.org/10.3891/acta.chem.scand.40b-0588.

Full text

APA, Harvard, Vancouver, ISO, and other styles

42

Pringouri, Konstantina, Muhammad U. Anwar, Bryce J. Leontowicz, and Jeremy M. Rawson. "Zinc complexes of 3-pyrimidinyl-benzo-1,2,4-thiadiazine." Polyhedron 150 (August 2018): 110–17. http://dx.doi.org/10.1016/j.poly.2018.05.004.

Full text

APA, Harvard, Vancouver, ISO, and other styles

43

Brough, P., R. Chiarelli, J. Pécaut, A. Rassat, and P. Rey. "A versatile synthesis of new pyrimidinyl nitronyl nitroxides." Chem. Commun., no. 21 (2003): 2722–23. http://dx.doi.org/10.1039/b309786b.

Full text

APA, Harvard, Vancouver, ISO, and other styles

44

Nestorak, Igor Yu, Anton V. Tverdokhlebov, Andrey A. Tolmachev, and Yulian M. Volovenko. "ChemInform Abstract: Synthesis of 3-(Pyrimidinyl)pyrrole Derivatives." ChemInform 41, no. 33 (July 24, 2010): no. http://dx.doi.org/10.1002/chin.201033102.

Full text

APA, Harvard, Vancouver, ISO, and other styles

45

Seenaiah, Dandu, Tamatam Rekha, Adivireddy Padmaja, and Venkatapuram Padmavathi. "Synthesis and antimicrobial activity of pyrimidinyl bis(benzazoles)." Medicinal Chemistry Research 26, no. 2 (December 21, 2016): 431–41. http://dx.doi.org/10.1007/s00044-016-1758-9.

Full text

APA, Harvard, Vancouver, ISO, and other styles

46

Giniyatullina, M. A., G. I. Podzigun, and V. S. Reznik. "Reactions of 2-pyrimidinyl phosphites with acyl chlorides." Bulletin of the Academy of Sciences of the USSR Division of Chemical Science 34, no. 11 (November 1985): 2416–18. http://dx.doi.org/10.1007/bf00956814.

Full text

APA, Harvard, Vancouver, ISO, and other styles

47

Danagulyan, G. G., N. G. Balasanyan, and M. G. Zalinyan. "Nucleophilic substitution in the O-pyrimidinyl ketoxime series." Chemistry of Heterocyclic Compounds 24, no. 4 (April 1988): 468. http://dx.doi.org/10.1007/bf00478872.

Full text

APA, Harvard, Vancouver, ISO, and other styles

48

Chen, Jing-Lin, Xue-Hua Zeng, Yan-Sheng Luo, Wan-Man Wang, Li-Hua He, Sui-Jun Liu, He-Rui Wen, Shuping Huang, Li Liu, and Wai-Yeung Wong. "Synthesis, structure, and photophysics of copper(i) triphenylphosphine complexes with functionalized 3-(2′-pyrimidinyl)-1,2,4-triazole ligands." Dalton Trans. 46, no. 38 (2017): 13077–87. http://dx.doi.org/10.1039/c7dt02848b.

Full text

Abstract:

The use of CF₃ group can enhance the solid-state luminescence of 1,2,4-triazole-based Cu(i) complexes but the use of Bu^t and pyrimidinyl groups and the 1,2,4-triazolyl-NH deprotonation do not favor this.

APA, Harvard, Vancouver, ISO, and other styles

49

Ramírez de Arellano, Carmen, Rosa Adam, Rafael Ballesteros-Garrido, Belen Abarca, Rafael Ballesteros, Ibon Alcorta, José Elguero, and Emilio Escrivà. "A C(π-hole)⋯Cl–Zn tetrel interaction driving a metal–organic supramolecular assembly." CrystEngComm 22, no. 42 (2020): 6979–82. http://dx.doi.org/10.1039/d0ce01272f.

Full text

Abstract:

A brominated pyrimidinyl triazolopyridine ligand (bptpy) forms a C(π-hole)⋯Cl–Zn tetrel interaction that drives the formation of supramolecular layers through chain assembly in 18 membered metallacycle [(ZnCl₂)₂(μ-bptpy)₂] crystals.

APA, Harvard, Vancouver, ISO, and other styles

50

Ji, Lei, Yun-Yan Kuang, Fen-Er Chen, and Min-Qin Chen. "2-(Cyclopentylsulfanyl)-6-(1-naphthoyl)pyrimidin-4(3H)-one." Acta Crystallographica Section E Structure Reports Online 62, no. 4 (March 22, 2006): o1485—o1487. http://dx.doi.org/10.1107/s1600536806009378.

Full text

Abstract:

In the structure of the title compound, C20H18N2O2S, the carbonyl group, the naphthyl ring system and the cyclopentyl ring are not in the plane of the pyrimidinyl ring. In the crystal structure, pairs of molecules are connected into dimers via N—H...O hydrogen bonding

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!