Relevant bibliographies by topics / Pyrido[3,4-b]indole dérivé

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  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters
  4. Conference papers

Academic literature on the topic 'Pyrido[3,4-b]indole dérivé'

Author: Grafiati
Published: 4 June 2021
Last updated: 5 February 2022

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Journal articles on the topic "Pyrido[3,4-b]indole dérivé"

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Koreňová, Anna, Alžbeta Krutošíková, Jaroslav Kováč, and Stanislav Celec. "Synthesis and reactions of furo[3,2-c]pyridine derivatives." Collection of Czechoslovak Chemical Communications 52, no. 1 (1987): 192–98. http://dx.doi.org/10.1135/cccc19870192.

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The synthesis of a new type of condensed heterocycle pyrido[3',4':4,5]furo[3,2-b]indole (V) and 1,2,4-triazolo[4'',3'':1',2']pyrido[3',4':4,5]furo[3,2-b]indoles (IX) is described and the substitution nucleophilic reaction with 2-(2-nitrophenyl)-4-chlorofuro[3,2-c]pyridine (X) is presented.
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2

Tada, Masao, Kazunori Sato, and Atsushi Oikawa. "Synthesis of 3-amino-1-methyl-9H-[4-14C]pyrido[3,4-b]indole (3-amino[4-14C]harman)." Journal of Labelled Compounds and Radiopharmaceuticals 24, no. 6 (June 1987): 631–36. http://dx.doi.org/10.1002/jlcr.2580240604.

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3

Maclaren, JA. "β-Carboline-3-carboxylic Acid (9H-Pyrido[3,4-b]indole-3-carboxylic Acid) and Related Compounds." Australian Journal of Chemistry 42, no. 6 (1989): 813. http://dx.doi.org/10.1071/ch9890813.

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The synthesis of β-carboline-3-carboxylic acid and its esters (4) by oxidation of the corresponding 1,2,3,4-tetrahydro derivatives (2) or of the 3,4-dihydro derivatives (3) has been studied. A novel synthesis of the esters (3) [and hence of (4)] has been achieved in high yield by cyclization and elimination from the enamine (5). The relative inhibition of binding of a benzodiazepine to rat brain membranes by the esters (2)-(4) has been determined.
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Manabe, Shigeo, Yoshikatsu Kanai, and Osamu Wada. "Exposure level monitor of 3-amino-1,4-dimethyl-5H-pyrido[4, 3-b]indole, a dietary carcinogen, in rabbits." Environmental and Molecular Mutagenesis 14, no. 1 (1989): 34–41. http://dx.doi.org/10.1002/em.2850140107.

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Misztal, Stanislaw, Maria H. Paluchowska, Maria J. Mokrosz, Piotr Bartyzel, and Jerzy L. Mokrosz. "Synthesis and stereochemistry of new trihydrodiazabicyclo-[3.m.n]alkano[4′,5′:1,2]pyrido[3,4-b]indole ring system." Journal of Heterocyclic Chemistry 30, no. 6 (December 1993): 1543–48. http://dx.doi.org/10.1002/jhet.5570300616.

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Domány, Gy, T. Gizur, G. Barta-Szalai, I. Schön, Cs Szántay, and B. Hegedüs. "Synthesis of new guanidine derivatives from 2′,3′,4′,9′-tetrahydrospiro[piperidine-4,1′-[1H]pyrido[3,4-b]indole]." Journal of Heterocyclic Chemistry 31, no. 6 (November 1994): 1657–60. http://dx.doi.org/10.1002/jhet.5570310664.

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Luo, Peng, Amar G. Chittiboyina, Mei Wang, Ikhlas A. Khan, Wei-Gao Pan, and Wan-Xing Wei. "Crystal structure of 12-(2-hydroxybenzoyl)benzo[f]pyrido[1,2-a]indole-6,11-dione, C23H13NO4." Zeitschrift für Kristallographie - New Crystal Structures 235, no. 1 (December 18, 2019): 105–7. http://dx.doi.org/10.1515/ncrs-2019-0524.

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Santos, Patricia Regina, Anelise S. Nazari Formagio, Benedito Prado Dias Filho, Celso Vataru Nakamura, Maria Helena Sarragiotto, and Tania Ueda-Nakamura. "Effect of 1-(phenyl)-N’-(4-methoxybenzylidene)-9H-pyrido[3,4-b] indole-3-carbohydrazide on in vitro poliovirus replication." Acta Pharmaceutica 65, no. 1 (March 1, 2015): 75–81. http://dx.doi.org/10.1515/acph-2015-0004.

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Abstract The effect of the alkaloid 1-(phenyl)-N’-(4-methoxybenzylidene)- 9H-pyrido[3,4-b]indole-3-carbohydrazide (PMC) on the poliovirus (PV) replication cycle in Vero cells was assayed by inhibition of the cytopathic effect (CPE) and inhibition of plaque forming units (PFU). Both methodologies suggested that the mode of action was avoidance of infection progression in the host cell. The compound was able to prevent CPE and PFU formation when the cells were pretreated with PMC for 24 h prior to PV infection. In addition, when the alkaloid was continuously maintained in the infected cultures, the spread of PV to adjacent cells was impaired. The pre-exposure and post-exposure prophylactic applications are possible situations in which an anti-PV drug might be used. Future studies are needed to elucidate the PMC mode of action and verify the feasibility of PMC use in vivo. No antipicornavirus agent is currently approved for clinical use
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DOMANY, GY, T. GIZUR, G. BARTA-SZALAI, I. SCHOEN, CS JUN SZANTAY, and B. HEGEDUES. "ChemInform Abstract: Synthesis of New Guanidine Derivatives from 2′,3′,4′,9′- Tetrahydrospiro(piperidine-4,1′-(1H)pyrido(3,4-b)indole)." ChemInform 26, no. 22 (August 18, 2010): no. http://dx.doi.org/10.1002/chin.199522179.

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DAMAVANDI, SAMAN, and REZA SANDAROOS. "Novel multicomponent synthesis of 2,9-dihydro-9-methyl-2-oxo-4-aryl-1H-pyrido[2,3-b]indole-3-carbonitrile compounds." Journal of Chemical Sciences 125, no. 1 (January 2013): 95–100. http://dx.doi.org/10.1007/s12039-013-0369-y.

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Dissertations / Theses on the topic "Pyrido[3,4-b]indole dérivé"

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Bahlaouan, Zineb. "Réactivité cupro-catalysée des systèmes mono, di et triiodés porteurs d'une fonction acide carboxylique ou dérivée : applications à la synthèse de nouveaux hétérocycles." Thesis, Tours, 2011. http://www.theses.fr/2011TOUR4035/document.

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Les hétérocycles oxygénés, azotés et soufrés sont des motifs présents dans de nombreux produits naturels possédant des activités biologiques intéressantes. Plusieurs publications décrivant la synthèse de ces hétérocycles en particulier oxygénés et azotés reposent sur l’utilisation des métaux de transition en tant que catalyseur.Dans notre cas, nous nous sommes intéressés dans un premier temps à la synthèse cupro-catalysée des pyrano[3’,4’:4,5]imidazo[1,2-a]pyridin-1-ones selon une réaction tandem impliquant un couplage et une hétérocyclisation, à partir des dérivés de l’acide 3-iodo-, 3,6- ou (3,8) diiodoimidazo[1,2-a]pyridine-2-carboxylique et d’alcynes vrais en présence de sels de cuivre (I) dans le DMF. Les réactions développées ne nécessitent aucune utilisation de métaux de transition plus coûteux comme les complexes au palladium par exemple
Heterocycles of oxygen, nitrogen and sulfur are patterns found in many natural products possessing interesting biological activities. Several researchers describe the synthesis of oxygen and nitrogen based heterocycles using transition metals as catalyst.In the present study, we focused initially on the copper-catalyzed synthesis of pyrano[3',4':4,5]imidazo[1,2-a]pyridin-1-ones by a tandem coupling-heterocyclisation reaction from derivatives of 3-iodo-, 3,6- or (3,8) diiodoimidazo[1,2-a]pyridine-2-carboxylic acid and terminal alkynes in the presence of copper (I) salts as catalyst in DMF. This procedure does not require the use of any expensive transition metal complexes like palladium and supplement any additives. The extension of this methodology to 2,3,5-triiodobenzoic acid allowed the regioselective synthesis of new isocoumarins substituted in positions 3, 5 and 7. Regioselective reactivity of iodine atoms in position 5 and 7 has been studied by palladium coupling reactions and nucleophilic substitution to broad its synthesis to a wide variety of new substituted isocoumarins
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Book chapters on the topic "Pyrido[3,4-b]indole dérivé"

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Negishi, Tomoe, Hiromi Nakano, Sakae Arimoto, Haruki Rai, and Hikoya Hayatsu. "Inhibitory Activity of Natural Chlorophylls on the Mutagenicity of 4-Nitroquinoline 1-Oxide and 3-Amino-1-Methyl-5H-Pyrido[4,3-b]indole in Drosophila." In Food Factors for Cancer Prevention, 581–84. Tokyo: Springer Japan, 1997. http://dx.doi.org/10.1007/978-4-431-67017-9_115.

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Conference papers on the topic "Pyrido[3,4-b]indole dérivé"

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Manabe, S., H. Yanagisawa, S. Ishikawa, Y. Kitagawa, K. Tohyama, S. Abe, and O. Wada. "TRYPTOPHAN PYROLYSIS PRODUCTS FOUND IN COOKED FOODS INHIBIT HUMAN PLATELET AGGREGATION BY INHIBITING CYCLOOXYGENASE." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643402.

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Humans are exposed to numerous toxic compounds in foods. During the past decade, several carcinogenic heterocyclic amines have been reported to be present in the cooked foods. Recently, we reported that some of the carcinogenic heterocyclic amines isolated from foods were present in human plasma. In order to know the effects of the carcinogens isolated from foods on the cell function, we investigated the effects of the carcinogenic heterocyclic amines including Trp-P-1(3-amino-l,4-dimethyl-5H-pyrido❘4,3-b❘indole) and Trp-P-2(3-amino-1-methyl-5H-pyrido❘4,3-b❘indole) on human platelet aggregation and polymorphonuclear leukocyte aggregation. Only tryptophan pyrolysis products, Trp-P-1 and Trp-P-2, had potent inhibitory effects on human platelet aggregation when platelets were preincubated with the carcinogens for 15 min. Other carcinogenic heterocyclic amines such as glutamic acid pyrolysates (Glu-P-1 and Glu-P-2) and 3H-imidazo ❘4,5-f❘quinoline-2-amines(IQ and MelQ) did show no effect on platelet aggregation even at 100 μM.The autoradiogram demonstrated that Tryptophan pyrolysis products, Trp-P-1 and Trp-P-2, dose-dependently inhibited the formation of HHT,PGD2,PGE2 and TXB2 induced by sodium arachidonate in human platelets labeled with ❘ 14c❘ arachidonic acid. Moreover, Trp-P-1 and Trp-P-2 did not show significant effects on leukocyte aggregation induced by sodium arachidonate (0.75mM) even at lOOnM. It is concluded that Trp-P-1 and Trp-P-2 isolated from cooked foodstuffs have potent inhibitory effects on the cyclo-oxygenase pathway of the platelet. Therefore, human platelet function might be affected with daily foods containing tryptophan pyrolysis products in vivo.
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