Relevant bibliographies by topics / PV1

Academic literature on the topic 'PV1'

Author: Grafiati
Published: 10 December 2022
Last updated: 29 January 2023

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Journal articles on the topic "PV1"

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Stan, Radu V., Eugene Tkachenko, and Ingrid R. Niesman. "PV1 Is a Key Structural Component for the Formation of the Stomatal and Fenestral Diaphragms." Molecular Biology of the Cell 15, no. 8 (August 2004): 3615–30. http://dx.doi.org/10.1091/mbc.e03-08-0593.

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PV1 is an endothelial-specific integral membrane glycoprotein associated with the stomatal diaphragms of caveolae, transendothelial channels, and vesiculo-vacuolar organelles and the diaphragms of endothelial fenestrae. Multiple PV1 homodimers are found within each stomatal and fenestral diaphragm. We investigated the function of PV1 within these diaphragms and their regulation and found that treatment of endothelial cells in culture with phorbol myristate acetate (PMA) led to upregulation of PV1. This correlated with de novo formation of stomatal diaphragms of caveolae and transendothelial channels as well as fenestrae upon PMA treatment. The newly formed diaphragms could be labeled with anti-PV1 antibodies. The upregulation of PV1 and formation of stomatal and fenestral diaphragms by PMA was endothelium specific and was the highest in microvascular endothelial cells compared with their large vessel counterparts. By using a siRNA approach, PV1 mRNA silencing prevented the de novo formation of the diaphragms of caveolae as well as fenestrae and transendothelial channels. Overexpression of PV1 in endothelial cells as well as in cell types that do not harbor caveolar diaphragms in situ induced de novo formation of caveolar stomatal diaphragms. Lastly, PV1 upregulation by PMA required the activation of Erk1/2 MAP kinase pathway and was protein kinase C independent. Taken together, these data show that PV1 is a key structural component, necessary for the biogenesis of the stomatal and fenestral diaphragms.
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Pogatzki-Zahn, E. "PV1. Pleanarvortrag: Transalationale Schmerzforschung." Perioperative Medizin 1, no. 4 (December 2009): 240. http://dx.doi.org/10.1016/j.periop.2009.08.012.

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Bell, Yolanda C., Bert L. Semler, and Ellie Ehrenfeld. "Requirements for RNA Replication of a Poliovirus Replicon by Coxsackievirus B3 RNA Polymerase." Journal of Virology 73, no. 11 (November 1, 1999): 9413–21. http://dx.doi.org/10.1128/jvi.73.11.9413-9421.1999.

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ABSTRACT A chimeric poliovirus type 1 (PV1) genome was constructed in which the 3D RNA polymerase (3Dpol) coding sequences were replaced with those from coxsackievirus B3 (CVB3). No infectious virus was produced from HeLa cells transfected with the chimeric RNA. Processing of the PV1 capsid protein precursor was incomplete, presumably due to inefficient recognition of the P1 protein substrate by the chimeric 3CD proteinase containing CVB3 3D sequences. The ability of the chimeric RNA to replicate in the absence of capsid formation was measured after replacement of the P1 region with a luciferase reporter gene. No RNA synthesis was detected, despite efficient production of enzymatically active 3Dpol from the 3D portion of the chimeric 3CD. The chimeric 3CD protein was unable to efficiently bind to the cloverleaf-like structure (CL) at the 5′ end of PV1 RNA, which has been demonstrated previously to be required for viral RNA synthesis. The CVB3 3CD protein bound the PV1 CL as well as PV1 3CD. An additional chimeric PV1 RNA that contained CVB3 3CD sequences also failed to produce virus after transfection. Since processing of PV1 capsid protein precursors by the CVB3 3CD was again incomplete, a luciferase-containing replicon was also analyzed for RNA replication. The 3CD chimera replicated at 33°C, but not at 37°C. Replacement of the PV1 5′-terminal CL with that of CVB3 did not rescue the temperature-sensitive phenotype. Thus, there is an essential interaction(s) between 3CD and other viral P2 or P3 protein products required for efficient RNA replication which is not fully achieved between proteins from the two different members of the same virus genus.
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Zhao, Yutong, and Jing Zhao. "PV1: Gatekeeper of Endothelial Permeability." American Journal of Respiratory Cell and Molecular Biology 63, no. 4 (October 2020): 413–14. http://dx.doi.org/10.1165/rcmb.2020-0294ed.

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Stan, Radu V. "Multiple PV1 dimers reside in the same stomatal or fenestral diaphragm." American Journal of Physiology-Heart and Circulatory Physiology 286, no. 4 (April 2004): H1347—H1353. http://dx.doi.org/10.1152/ajpheart.00909.2003.

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Several of the endothelium-specific structures that have been involved in microvascular permeability [such as caveolae, transendothelial channels (TECs), vesiculovacuolar organelles (VVOs), and fenestrae] can be provided with either a stomatal or fenestral diaphragm. In the case of fenestrae, the diaphragm has the presumed function of creating a permselective barrier for solutes from blood plasma and interstitium. PV1 is an endothelium-specific integral membrane glycoprotein that is associated with both the stomatal diaphragms of caveolae, TECs, and VVOs as well as the diaphragms of endothelial fenestrae. The intimate structure of these diaphragms has been shown to consist of a meshwork formed by radial fibrils. We have recently shown that PV1 is a key structural element of both types of diaphragms, with its expression being sufficient to form de novo stomatal and fenestral diaphragms in both endothelial and nonendothelial cell types in culture. We have further tested the role of PV1 in the structure of the diaphragms and demonstrate here that multiple PV1 homodimers reside in close proximity within the same diaphragm. Our data bring further support to the paradigm by which PV1 dimers would form the fibrils of the diaphragms with a function in the microvascular permeability.
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Cornell, Christopher T., Rushika Perera, Jo Ellen Brunner, and Bert L. Semler. "Strand-Specific RNA Synthesis Determinants in the RNA-Dependent RNA Polymerase of Poliovirus." Journal of Virology 78, no. 9 (May 1, 2004): 4397–407. http://dx.doi.org/10.1128/jvi.78.9.4397-4407.2004.

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ABSTRACT The viral RNA-dependent RNA polymerase (3Dpol) is highly conserved between the closely related enteroviruses poliovirus type 1 (PV1) and coxsackievirus B3 (CVB3). In this study, we generated PV1/CVB3 chimeric polymerase sequences in the context of full-length poliovirus transcripts to determine the role of different subdomains within the RNA-dependent RNA polymerase of PV1 that are required for functions critical for RNA replication in vitro and in cell culture. The substitution of CVB3 sequences in the carboxy-terminal portion (thumb subdomain) of the polymerase resulted in transcripts incapable of RNA replication. In contrast, three of the seven chimeras were capable of synthesizing RNA, albeit to reduced levels compared to that of wild-type PV1 RNA. Interestingly, one of the replication-competent chimeras (CPP) displayed an inability to generate positive strands, indicating the presence of amino-terminal sequences within the 3D polymerase and/or the 3D domain of the 3CD precursor polypeptide that are necessary for the assembly of strand-specific RNA synthesis complexes. In some constructs, the partial reestablishment of PV1 amino acid sequences in this region was capable of rescuing RNA replication in vitro and in cell culture.
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Simonet, Julien, and Christophe Gantzer. "Inactivation of Poliovirus 1 and F-Specific RNA Phages and Degradation of Their Genomes by UV Irradiation at 254 Nanometers." Applied and Environmental Microbiology 72, no. 12 (October 13, 2006): 7671–77. http://dx.doi.org/10.1128/aem.01106-06.

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ABSTRACT Several models (animal caliciviruses, poliovirus 1 [PV1], and F-specific RNA bacteriophages) are usually used to predict inactivation of nonculturable viruses. For the same UV fluence, viral inactivation observed in the literature varies from 0 to 5 logs according to the models and the methods (infectivity versus molecular biology). The lack of knowledge concerning the mechanisms of inactivation due to UV prevents us from selecting the best model. In this context, determining if viral genome degradation may explain the loss of infectivity under UV radiation becomes essential. Thus, four virus models (PV1 and three F-specific RNA phages: MS2, GA, and Qβ) were exposed to UV radiation from 0 to 150 mJ · cm−2. PV1 is the least-resistant virus, while MS2 and GA phages are the most resistant, with phage Qβ having an intermediate sensitivity; respectively, 6-log, 2.3-log, 2.5-log, and 4-log decreases for 50 mJ · cm−2. In parallel, analysis of RNA degradation demonstrated that this phenomenon depends on the fragment size for PV1 as well as for MS2. Long fragments (above 2,000 bases) for PV1 and MS2 fell rapidly to the background level (>1.3-log decrease) for 20 mJ · cm−2 and 60 mJ · cm− 2, respectively. Nevertheless, the size of the viral RNA is not the only factor affecting UV-induced RNA degradation, since viral RNA was more rapidly degraded in PV1 than in the MS2 phage with a similar size. Finally, extrapolation of inactivation and UV-induced RNA degradation kinetics highlights that genome degradation could fully explain UV-induced viral inactivation.
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Ponnuraj, Esther M., T. Jacob John, Myron J. Levin, and Eric A. F. Simoes. "Sabin attenuated LSc/2ab strain of poliovirus spreads to the spinal cord from a peripheral nerve in bonnet monkeys (Macaca radiata)." Journal of General Virology 82, no. 6 (June 1, 2001): 1329–38. http://dx.doi.org/10.1099/0022-1317-82-6-1329.

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Vaccine-associated paralytic poliomyelitis is a serious concern while using the live attenuated oral polio vaccine for the eradication of poliomyelitis. The bonnet monkey model of poliovirus central nervous system (CNS) infection following experimental inoculation into the ulnar nerve allows the comparative study of wild-type and attenuated poliovirus invasiveness. Dosages ⩾104 TCID50 of Mahoney strain of poliovirus type 1 [PV1(M)] result in paralysis. In contrast, even with 107 TCID50 of Sabin attenuated strain of poliovirus type 1 (LSc/2ab), no paralysis occurs, but virus spreads into the CNS where viral RNA is found in spinal cord neurons. While wild-type PV1(M) viral RNA replicates in neurons (and possibly in glial cells) and in cells around vessel walls, which may be mononuclear or endothelial cells, attenuated viral RNA is detected only in neurons. Systemic viraemia and gastrointestinal virus shedding occurs only in PV1(M)-infected animals. While a systemic serologic response is detected in both groups of animals, cerebrospinal fluid antibodies are detected only in animals infected with PV1(M). Both the PV1(M) and LSc/2ab strains spread to the cervical spinal cord and then to the lumbar spinal cord following ulnar nerve inoculation. Neuronophagia and neuronal loss are only seen in PV1(M)-infected monkeys in whom clinical paralysis is observed. Infection with LSc/2ab does not result in neuronophagia, neuronal loss or clinical paralysis. Spread of attenuated poliovirus in spinal cord neurons without causing paralysis following inoculation into the ulnar nerve is an important finding.
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Larocca, Angela Maria Vittoria, Francesco Paolo Bianchi, Anna Bozzi, Silvio Tafuri, Pasquale Stefanizzi, and Cinzia Annatea Germinario. "Long-Term Immunogenicity of Inactivated and Oral Polio Vaccines: An Italian Retrospective Cohort Study." Vaccines 10, no. 8 (August 17, 2022): 1329. http://dx.doi.org/10.3390/vaccines10081329.

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Oral and inactivated poliovirus (PV) vaccines have contributed toward the global eradication of wild PV2 and PV3, as well as the elimination of PV1 in most countries. While the long-term (>5–10 years) persistence of protective antibodies in ≥80% of the population vaccinated with ≥3–4 doses of oral poliovirus vaccine (OPV) has been demonstrated, the duration of immunity in people vaccinated with the inactivated poliovirus vaccine (IPV) is still unclear. This study evaluated the seroprevalence of anti-PV neutralizing antibodies and the long-term immunogenicity conferred by OPV and IPV in a sample of medical students from the University of Bari (April 2014–October 2020). The levels of neutralizing PV1, PV2, and PV3 antibodies in blood samples taken during the assessments were evaluated. Neutralizing antibodies against PV1, PV2, and PV3 were present in >90% of the study participants, with rates of >99%, >98%, and ~92–99%, respectively. IPV resulted in a higher immunological response than OPV against PV3. Protective antibodies against all three viruses persisted for at least 18 years after administration of the last vaccine dose. Until PV1 is completely eradicated, maximum vigilance from public health institutions must be maintained.
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Nagata, Noriyo, Takuya Iwasaki, Yasushi Ami, Yoshio Tano, Ayako Harashima, Yuriko Suzaki, Yuko Sato, et al. "Differential localization of neurons susceptible to enterovirus 71 and poliovirus type 1 in the central nervous system of cynomolgus monkeys after intravenous inoculation." Journal of General Virology 85, no. 10 (October 1, 2004): 2981–89. http://dx.doi.org/10.1099/vir.0.79883-0.

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Poliovirus and enterovirus 71 (EV71) are both neurotropic enteroviruses that cause serious neurological diseases, such as poliomyelitis and encephalitis. The neurovirulence of EV71 in cynomolgus monkeys was demonstrated previously by intraspinal inoculation. In this study, an improved simian model of EV71 infection was established by using intravenous inoculation, which revealed clinical and neuropathological similarities between this model and human cases of encephalitis. Experimental EV71 infection induced direct neurological manifestations, such as tremor, ataxia and brain oedema, but not non-neurological complications, such as pulmonary oedema and cardiac failure. Using this model of EV71 infection, the neurotropic characteristics of the prototype strains of EV71 and poliovirus type 1 (PV1) were compared. Three monkeys were inoculated intravenously with 105·5 TCID50 EV71 and all developed neurological disease signs within 4–6 days of inoculation. However, after inoculation with 105·5 TCID50 PV1 strain OM1 (PV1-OM1), the major manifestation was flaccid paralysis, starting from the lower limbs 6–9 days post-inoculation. Histopathological and virological analyses of moribund monkeys revealed that disseminated EV71 infection was characterized by severe panencephalitis involving both the pyramidal and extrapyramidal systems. In contrast, the lesions induced by PV1-OM1 were mainly restricted to the pyramidal tract, particularly the spinal motor neurons, thalamus and motor cortex. In conclusion, neuropathological involvement in this model correlated well with the apparent differences in neurological disease induced by EV71 and PV1-OM1. Thus, intravenous inoculation with EV71 is an excellent model to study the neuropathology of EV71 and to evaluate candidate vaccines and potential antiviral agents.
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Dissertations / Theses on the topic "PV1"

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Rosa, Pedro Henrique Papotto. "Avaliação da eficiência do antagonista seletivo de CD28, mPEG PV1-Fab´, no tratamento da uveíte autoimune experimental." Universidade de São Paulo, 2014. http://www.teses.usp.br/teses/disponiveis/42/42133/tde-14032015-101012/.

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A uveíte autoimune é uma doença inflamatória crônica, caracterizada pela resposta imune a antígenos oculares. É mediada por linfócitos T CD4+ com perfil TH1, e responsável por uma parcela significativa de casos de deficiências visuais e cegueira. Embora efetivos, os tratamentos disponíveis estão associados a efeitos adversos importantes. Logo, a busca de novos alvos terapêuticos mais específicos tem sido o objetivo principal no campo da imunoterapia. Nesse trabalho foi avaliada a eficiência do antagonista seletivo de CD28, mPEG PV1-Fab´(PV1), no tratamento da uveíte autoimune experimental (EAU). Camundongos tratados com PV1 exibiram menores graus de doença quando comparados a controles não tratados. Tal achado foi acompanhado de uma diminuição da ativação de linfócitos T, tanto nos olhos quanto nos órgãos linfoides periféricos desses animais. Mais ainda, o tratamento com PV1 levou a uma diminuição da população de linfócitos T reguladores e de células do tipo TH1. Portanto, concluiu-se que PV1 é eficaz no tratamento da EAU por agir em linfócitos T efetores.
Autoimmune uveitis is a T-cell mediated disease that targets mainly the posterior eye pole. Similar to human uveitis, experimental autoimmune uveitis (EAU) is mostly dependent on T cells with a TH1 phenotype. Although many treatment strategies are available, most of them focus on general immunossuppression, resulting in undesirable side effects. Thus, the development of more specific therapies is the major aim in the field of immunotherapy. Here we evaluated the efficacy of mPEG PV-1-Fab´ (PV1), a specific CD28 antagonist, in the treatment of EAU. Our results indicate that PV1 blocks T cell activation by decreasing expression of different costimulatory molecules. Furthermore, PV1 treatment led to a decrease of Treg cell population in peripheral lymphoid organs. Also, IFN-g production by CD4+ cells and TH1 lymphocytes population were decreased. Altogether, our results raise this CD28 blockade strategy as a potential tool for the treatment of autoimmune disorders in the eye, and indicate that mPEG PV1-Fab acts mainly on IFN-g production and TH1 polarization.
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Lee-Montiel, Felipe, Kelly Reynolds, and Mark Riley. "Detection and quantification of poliovirus infection using FTIR spectroscopy and cell culture." BioMed Central, 2011. http://hdl.handle.net/10150/610169.

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BACKGROUND:In a globalized word, prevention of infectious diseases is a major challenge. Rapid detection of viable virus particles in water and other environmental samples is essential to public health risk assessment, homeland security and environmental protection. Current virus detection methods, especially assessing viral infectivity, are complex and time-consuming, making point-of-care detection a challenge. Faster, more sensitive, highly specific methods are needed to quantify potentially hazardous viral pathogens and to determine if suspected materials contain viable viral particles. Fourier transform infrared (FTIR) spectroscopy combined with cellular-based sensing, may offer a precise way to detect specific viruses. This approach utilizes infrared light to monitor changes in molecular components of cells by tracking changes in absorbance patterns produced following virus infection. In this work poliovirus (PV1) was used to evaluate the utility of FTIR spectroscopy with cell culture for rapid detection of infective virus particles.RESULTS:Buffalo green monkey kidney (BGMK) cells infected with different virus titers were studied at 1 - 12 hours post-infection (h.p.i.). A partial least squares (PLS) regression method was used to analyze and model cellular responses to different infection titers and times post-infection. The model performs best at 8 h.p.i., resulting in an estimated root mean square error of cross validation (RMSECV) of 17 plaque forming units (PFU)/ml when using low titers of infection of 10 and 100 PFU/ml. Higher titers, from 103 to 106 PFU/ml, could also be reliably detected.CONCLUSIONS:This approach to poliovirus detection and quantification using FTIR spectroscopy and cell culture could potentially be extended to compare biochemical cell responses to infection with different viruses. This virus detection method could feasibly be adapted to an automated scheme for use in areas such as water safety monitoring and medical diagnostics.
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Cabrera, Sotelo Julieta Gladys. "Hidrogeles de PVA-PVP conteniendo nanopartículas de plata obtenidos por radiación gamma." Universidad Nacional de Ingeniería. Programa Cybertesis PERÚ, 2009. http://cybertesis.uni.edu.pe/uni/2009/cabrera_sj/html/index-frames.html.

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Amaral, Renata Hage. "Estudo da incorporação e liberação de um extrato de algas vermelhas em membranas de hidrogel." Universidade de São Paulo, 2009. http://www.teses.usp.br/teses/disponiveis/85/85134/tde-16112009-145201/.

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Os hidrogéis estão dentre as matrizes poliméricas mais utilizadas em tecnologia farmacêutica em razão de sua vasta aplicação e funcionalidade, especialmente em sistema de liberação de fármacos. Tendo em vista o grande avanço nas inovações dos produtos cosméticos, tanto por meio da introdução de novos princípios ativos quanto pelas matrizes utilizadas para liberação controlada dos mesmos, o objetivo deste trabalho foi incorporar e avaliar a liberação de um princípio ativo natural, o ArctAlg®, em membranas de hidrogel, de modo a obter um dispositivo de liberação para fins cosméticos. O ArctAlg® é um extrato aquoso que possui uma excelente ação anti-oxidante, lipolítica, anti-inflamatória e citoestimulante. Foi realizado o estudo das propriedades mecânicas, físicoquímicas e a biocompatibilidade in vitro das membranas de hidrogéis de poli(vinil- 2- pirrolidona) (PVP) e poli(vinil álcool) (PVA) obtidas pela reticulação por radiação ionizante. A caracterização físico-química das matrizes poliméricas foi obtida pelos ensaios de fração gel e intumescimento e o de biocompatibilidade in vitro pelo ensaio de citotoxicidade pelo método de incorporação do vermelho neutro. No ensaio de fração gel tanto o hidrogel de PVP quanto o de PVA apresentaram um alto grau de reticulação. O hidrogel de PVP apresentou uma maior porcentagem de intumescimento em relação ao de PVA e no ensaio de citotoxicidade os hidrogéis mostraram-se atóxicos. A propriedade citoestimulante do ArctAlg® foi verificada no ensaio de citoestimulação com células fibroblásticas de pele de coelho, em que foi evidenciado um aumento de cerca de 50% das células quando em contato com 0,5% do princípio ativo. As membranas de hidrogel preparadas com 3% de ArctAlg® foram submetidas ao ensaio de liberação em incubadora a 37ºC e as alíquotas coletadas durante o ensaio foram quantificadas por cromatografia líquida de alta eficiência (HPLC). Os resultados obtidos na cinética de liberação mostraram que as membranas de hidrogel de PVP liberaram cerca de 50% do ArctAlg® incorporado e as de PVA em cerca de 30%. No ensaio de citoestimulação do ArctAlg® liberado, o dispositivo de PVP apresentou um aumento em cerca de 80% da população celular em relação ao controle do ensaio, mostrando ser o dispositivo mais indicado para ser utilizado em processos de reparação cutânea.
In pharmaceutical technology hydrogel is the most used among the polymeric matrices due to its wide application and functionality, primarily in drug delivery system. In view of the large advance innovations in cosmetic products, both through the introduction of new active agents as the matrices used for its controlled release, the objective of this study was to evaluate the release and immobilization of a natural active agent, the Arct\'Alg® in hydrogel membranes to obtain a release device for cosmetics. Arct\'Alg® is an aqueous extract which has excellent anti-oxidant, lipolytic, anti-inflammatory and cytostimulant action. Study on mechanical and physical-chemical properties and biocompatibility in vitro of hydrogel membranes of poly(vinyl-2- pyrrolidone) (PVP) and poly(vinyl alcohol) (PVA) obtained by ionizing radiation crosslinking have been performed. The physical-chemical characterization of polymeric matrices was carried out by gel fraction and swelling tests and biocompatibility by in vitro test of cytotoxicity by using the technique of neutral red incorporation. In the gel fraction test, both the PVP and PVA hydrogel showed a high crosslinking degree. The PVP hydrogel showed a greater percentage of swelling in relation to PVA and the cytotoxicity test of the hydrogels showed non-toxicity effect. The cytostimulation property of Arct\'Alg® was verified by the cytostimulation test with rabbit skin cells, it was showed an increase at about 50% of the cells when in contact with 0,5% of active agent. The hydrogel membranes prepared with 3% of Arct\'Alg® were subjected to the release test in an incubator at 37°C and aliquots collected during the test were quantified by high performance liquid chromatography (HPLC). The results obtained in the kinetics of release showed that the PVP hydrogel membranes released about 50% of Arct\'Alg® incorporated and the PVA hydrogel membranes at about 30%. In the cytostimulation test of released Arct\'Alg®, the PVP device showed an increase at about 80% of cell population in relation of test control, showing to be the greater device to be used in processes of skin repair.
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Farias, Italo Fernando. "Estudo da influência da radiação gama nas propriedades mecânicas e térmicas de \"elastômeros termoplásticos\" blendas de poli (cloreto de vinila) com poli (vinil butiral)." Universidade de São Paulo, 2018. http://www.teses.usp.br/teses/disponiveis/85/85134/tde-11102018-083413/.

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A vasta gama de sistemas poliméricos classificados como blendas tem sido alvo crescente no meio acadêmico e científico. A possibilidade de obtenção de propriedades combinadas e múltiplas, associada a incorporações de blendas poliméricas, enriquece a condição de pesquisa abrindo assim uma extensa área de atuação. Neste trabalho foi proposto o estudo de mistura de composto de poli (cloreto de vinila) plastificado com resíduo de poli (vinil butiral), proveniente de laminados para produção de para-brisas da indústria automotiva, bem como a investigação do efeito da irradiação gama com dose absorvida de 25 kGy, 30 kGy e 40 kGy, controlado com uso de dosímetro de PMMA e taxa de dose equivalente de 0-10 kGy.h-1. Foram analisadas variações das propriedades mecânicas e térmicas das amostras antes e após exposição à radiação gama. As formulações foram constituídas em diferentes concentrações: composto de PVC-C, resíduo de PVB-R, PVC-C/PVB-R 90/10, PVC-C/PVB-R 50/50 e PVC-R/PVB-R 50/50. O composto de poli (cloreto de vinila) foi formulado e aditivado, apresentando comportamento de um elastômero termoplástico, produto flexível. Foram incorporadas aparas moídas de poli (vinil butiral), provenientes de laminados para produção de para-brisas. Ambos os materiais foram incorporados em extrusora granuladora tipo rosca simples e submetidos ao processo de calandragem para efetivação da mistura e formação de mantas plásticas. As mantas foram irradiadas em um reator multipropósito de 60Co e caracterizadas para verificação das propriedades mecânicas e térmicas. Para tanto, as blendas após exposição à radiação gama apresentaram propriedades mecânicas e térmicas intermediarias as propriedades dos seus componentes, mostrando-se um material resistente e de baixo custo. Por meio da microscopia eletrônica de varredura obteve uma redução nos vasos interfaciais mostrando um aumento na capacidade de percolação do PVB na matriz de PVC, favorecendo suas propriedades físicas.
The wide range of polymer systems classified as blends has been increasingly targeted in the academic and scientific milieu. The possibility of obtaining multiple and combined properties, combined with the incorporation of polymer blends, enriches the research condition, thus opening up an extensive area of performance. In this work the study of the poly (vinyl butyral) plasticized polyvinyl chloride mixture from laminates for automotive windshield production was investigated, as well as the investigation of the effect of gamma irradiation with absorbed dose of 25 kGy, 30 kGy and 40 kGy, controlled with use of PMMA dosimeter and equivalent dose rate of 0-10 kGy.h-1. Variations of the mechanical and thermal properties of the samples were analyzed before and after exposure to gamma radiation. The formulations were constituted in different concentrations: PVC-C compound, PVB-R residue, PVC-C/PVB-R 90/10, PVC-C/PVB-R 50/50 and PVC-R/PVB-R 50/50. The polyvinyl chloride compound was formulated and added, exhibiting the behavior of a thermoplastic elastomer, a flexible product. Poly (vinyl butyral) ground chips were produced from laminates for the production of windshields. Both materials were incorporated in a single-thread granulator extruder and submitted to the calendering process to effect the mixing and formation of plastic blankets. The blankets were irradiated in a 60Co multipurpose reactor and characterized for verification of mechanical and thermal properties. In order to do so, the blends after exposure to gamma radiation presented mechanical properties and intermediate thermal properties of their components, showing a resistant material and low cost. By means of the scanning electron microscopy it obtained a reduction in the interfacial vessels showing an increase in the percolation capacity of the PVB in the PVC matrix, favoring its physical properties.
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Hong, Sathapanaroth Satha. "Modélisation de dispersions eau-VCM-PVC en présence de tensio-actifs macromoléculaires à base de PVA." Mulhouse, 2005. http://www.theses.fr/2005MULH0784.

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L'objectif de cette étude est de préparer et de caractériser des nanoparticules à base d'alcool polyvinylique (PVA) qui pourront par la suite être utilisées comme stabilisants particulaires de type "Pickering" lors de la polymérisation en suspension du chlorure de vinyle (VCM). Du fait de la toxicité du VCM, un solvant modèle, le chlorobutane (CIBu), est utilisé à la place du VCM dans l'étude de l'émulsion de départ. Nous avons ainsi montré qu'il est possible d'o6tenir, par un procédé de coacervation, des dispersions aqueuses à base de PVA formées de nanoparticules colloïdales monodisperses en taille, de diamètre compris entre 150 et 300 nm. Les différentes techniques de caractérisation utilisées ont permis de mettre en évidence une structure sphérique de type "coeur-couronne" des nanoparticules dont la composition joue un rôle important sur leur capacité à stabiliser l'émulsion CIBu/eau, une stabilisation de type "Pickering" étant plus favorable qu'une stabilisation purement stérique
The objective of this study was to prepare and to characterize colloidal particles based on polyvinyl alcohol (PVA) which could be used as particie stabilizers, called "Pickering" stabilizers, in suspension polymerization of vinyl chloride (VCM). Due to VCM toxicity, a model solvent, butyl chloride (CIBu), is used instead of VCM in the initial emulsion study. We have shown that it is possible to obtain, with a coacervation technique, aqueous dispersions based on PVA formed by colloidal particles monodispersed in size, with a diameter between 150 and 300 nm. Different characterization techniques, enabied to demonstrate a spherical "core-shell" structure of the nanoparticles which composition plays an important role on their ability to stabilise CIBu/water emulsion, a "Pickering" stabilisation being better than a pure steric stabilisation
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AMARAL, RENATA H. "Estudo da incorporacao e liberacao de um extrato de algas vermelhas em membranas de hidrogel." reponame:Repositório Institucional do IPEN, 2009. http://repositorio.ipen.br:8080/xmlui/handle/123456789/9445.

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Instituto de Pesquisas Energeticas e Nucleares - IPEN-CNEN/SP
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Schubert, Martin Verfasser], Marcus A. [Akademischer Betreuer] [Glomb, and Thomas [Akademischer Betreuer] Simat. "Untersuchungen zum Einsatz von PVI, PVP bei Bier und Wein / Martin Schubert. Betreuer: Marcus Glomb ; Thomas Simat." Halle, Saale : Universitäts- und Landesbibliothek Sachsen-Anhalt, 2011. http://d-nb.info/1025231163/34.

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Shapla, Tanweer J. "INFERENCE OF ATTRIBUTABLE RISK FOR MULTIPLE EXPOSURE LEVELS UNDER CROSS-SECTIONAL SAMPLING DESIGN." Bowling Green State University / OhioLINK, 2006. http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1148489335.

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Junkunlo, Kingkamon. "Regulation of hematopoiesis in the freshwater crayfish, Pacifastacus leniusculus : role of transglutaminase." Doctoral thesis, Uppsala universitet, Jämförande fysiologi, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-327921.

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The freshwater crayfish, Pacifastacus leniusculus, has been used as a model for studying hematopoiesis or blood cell production or hematopoiesis and immunity. The work of this thesis aims to investigate the impact of factors such as ROS signaling, Ast1, and the PVF/PVR signaling pathway in controlling stem cell behavior during hematopoiesis and specifically the role of the crosslinking enzyme transglutaminase (TGase) in regulation of hematopoiesis. The role of ROS in crayfish hematopoiesis was characterized by using the antioxidant named NAC to inhibit ROS production. Low ROS level resulted in a prolonged decrease in hemocyte numbers and a combined injection of LPS and NAC caused a slower rate of new hemocyte production. A low ROS level in cell cultures supplemented with crude Ast1 was found to inhibit cell spreading and a high extracellular TGase activity was detected on the surfaces of APC and HPT cells. We suggest that ROS serves as a prime signal to control proliferation and differentiation of progenitor cells by affecting extracellular TGase activity. We reported an inhibitory effect of Ast1 on TGase enzyme activity and on its crosslinking activity and consequently Ast1 affects the clot formation and thus coagulation by inhibiting the crosslinking activity of the TGase enzyme. Secretion of the clot protein (CP) and the production of CP filament network between spreading cells were observed in HPT cell cultures in vitro. In the presence of CP together with Ast1 in 3D-collagen-I cultures, HPT cells were found to be more elongated and they formed chains of cells throughout the surrounding matrix. In the HPT tissue, CP was located around the HPT cells or around the lobules of HPT, and thus, CP was demonstrated to be a part of ECM and to possibly function together with collagen in generating a suitable environment for HPT progenitor cells. The inhibition of PVF/PVR downstream signaling pathway by Sunitinib malate resulted in a dramatic change of cell morphology and induction of an increase cell surface area during cell culture. The addition of crude Ast1 into the cell cultures in vitro enhanced this effect. Consequently, cell migration was stimulated and a high extracellular TGase activity on HPT cell surface was found after this inhibition. In conclusion, the work in this thesis provides new insight in understanding the role of the extracellular matrix (ECM) and extracellular TGase activity in controlling stem cell activity.
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Books on the topic "PV1"

1

Baldwin, Edward A. PVC furniture. Blue Ridge Summit, PA: TAB Books, 1992.

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Vaṃ, Dhū. Le pve. Ranʻ kunʻ: Yamunā Cā pe Phranʻʹ khyi reʺ, 1990.

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W, Summers J., and Daniels C. A. 1943-, eds. PVC handbook. Cincinnati: Hanser Gardner Publications, 2005.

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Röhrl, Eckhard. PVC-Taschenbuch. München: Carl Hanser Verlag GmbH & Co. KG, 2007. http://dx.doi.org/10.3139/9783446411777.

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Schiller, Michael. PVC Additives. München: Carl Hanser Verlag GmbH & Co. KG, 2015. http://dx.doi.org/10.3139/9781569905449.

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McLure, James. Pvt. wars. New York, N.Y. (440 Park Ave. S., New York 10016): Dramatists Play Service, 1990.

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Titow, W. V. PVC Plastics. Dordrecht: Springer Netherlands, 1991. http://dx.doi.org/10.1007/978-94-011-3834-5.

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Schiller, Michael. PVC Stabilisatoren. München: Carl Hanser Verlag GmbH & Co. KG, 2010. http://dx.doi.org/10.3139/9783446425767.

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Roberts, Clifford Charlie. PVC sculptured birdhouses. [Ronda, NC] (Rt. 1, Box 403, Ronda 28670-9759): C.C. Roberts, 1992.

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Krumm, Rob. Using a PS1. Portland, Ore: MIS Press, 1991.

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Book chapters on the topic "PV1"

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Zhouxiang, Lu. "From PvC to PvP." In A History of Competitive Gaming, 83–160. New York: Routledge, 2022. http://dx.doi.org/10.4324/9781003095859-4.

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Jacobs, Bart, and John Rushby. "PVS." In The Seventeen Provers of the World, 24–27. Berlin, Heidelberg: Springer Berlin Heidelberg, 2006. http://dx.doi.org/10.1007/11542384_5.

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Gooch, Jan W. "PVA." In Encyclopedic Dictionary of Polymers, 597. New York, NY: Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-6247-8_9632.

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Gooch, Jan W. "PVB." In Encyclopedic Dictionary of Polymers, 598. New York, NY: Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-6247-8_9635.

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Gooch, Jan W. "PVC." In Encyclopedic Dictionary of Polymers, 598. New York, NY: Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-6247-8_9636.

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Gooch, Jan W. "PVD." In Encyclopedic Dictionary of Polymers, 598. New York, NY: Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-6247-8_9638.

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Gooch, Jan W. "PVF." In Encyclopedic Dictionary of Polymers, 598. New York, NY: Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-6247-8_9641.

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Gooch, Jan W. "PVI." In Encyclopedic Dictionary of Polymers, 598. New York, NY: Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-6247-8_9643.

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Gooch, Jan W. "PVK." In Encyclopedic Dictionary of Polymers, 598. New York, NY: Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-6247-8_9645.

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Gooch, Jan W. "PVP." In Encyclopedic Dictionary of Polymers, 598. New York, NY: Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-6247-8_9648.

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Conference papers on the topic "PV1"

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Santos, Fabricia Ferreira Dos, Lucas Adrial Tavares Santos, Savyo Nunes De Oliveira, Irinaldo Diniz Basílio Júnior, and Valdemir Da Costa Silva. "AVALIAÇÃO DO PERFIL DE QUALIDADE E A ATIVIDADE ANTIMICROBIANA DE EXTRATOS DA PRÓPOLIS VERMELHA COMERCIALIZADOS EM ALAGOAS." In III Congresso Brasileiro de Ciências Farmacêuticas On-line. Revista Multidisciplinar em Saúde, 2022. http://dx.doi.org/10.51161/conbracif/21.

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Introdução: A própolis vermelha (PV) é um produto natural de composição química complexa e exclusiva produzida por abelhas Apis mellífera. O crescente uso popular do extrato de própolis vermelha ocorre devido suas propriedades biológicas e tem gerado a comercialização do extrato de maneira irregular. Objetivos: Objetivou-se nesse trabalho avaliar o perfil de qualidade e a atividade antimicrobiana de extratos da PV comercializados em Alagoas. Material e métodos: Os extratos foram obtidos em estabelecimentos comerciais de Maceió e denominados como: PV (A, B, C, D e E). O controle de qualidade foi realizado quanto aos aspectos organolépticos, teor de sólidos solúveis, fenóis e flavonoides totais. A atividade antioxidante foi avaliada pelo método DPPH. A atividade antimicrobiana foi realizada através da concentração inibitória mínima (CIM). Resultados: Os resultados revelam que os extratos tinham coloração e aroma similar. Apenas o extrato PVE apresentou teor de extrato seco acima de 11% de acordo com o Ministério da Agricultura, Pecuária e Abastecimento (MAPA). O extrato PVB revelou o maior teor de compostos fenólicos com 210,4 ± 2,4 mgEAG. g-1. Já o extrato PVC apresentou maior índice de flavonoides totais com 118,2 ± 4,2 mgEQ; g-1. Quando avaliado a atividade antioxidante destaca-se a PVC com maior capacidade de inibir o radical DPPH (87,8 ± 2,9 %). Os extratos PVC, PVD e PVE, apresentaram menor CIM (15,625 µg/mL) frente a E. coli e S. aureus. Conclusão: Diante do exposto, somente o extrato PVE foi satisfatório de acordo com o MAPA. Os demais extratos foram satisfatórios após ajuste de concentração, demonstrando a necessidade de maior controle de qualidade na comercialização.
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Kolychikhina, M. S. "Positive effect of preparations with antiviral properties on potato productivity." In Растениеводство и луговодство. Тимирязевская сельскохозяйственная академия, 2020. http://dx.doi.org/10.26897/978-5-9675-1762-4-2020-111.

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In the small-plot experiment of the Russian State Agrarian University - Moscow Timiryazev Agricultural Academy against potato viruses in 2014-2019 were tested some kinds of preparations with antiviral activity: Pharmayod, GS (100 g/l of iodine); Immunocytophyte, TAB (20 g/kg arachidonic acid ethyl ester); Ecogel, WS (30 g/l of chitosan lactate); Amulet, TAB (composition of linear polyaminosaccharides (chitosan) in succinic acid solution); Zerox, WS (3000 mg /l colloidal silver); Viron, WS (biostimulant based on urea and citric acid with the addition of essential oils). According to the results of the studies, it was found that, in addition to the effect on the causative agents of viral diseases of potatoes, all tested preparations had a stable tendency to maintain or increase the yield of tubers of infected plants. The increase in the yield of tubers ranged from 0.5 to 1.3 kg/m2. In 2016 under the production conditions of Astrakhan region on the potato variety Impala infected with the PVM + PVS and PVM + PVS + PVY virus complexes a comparative assessment of the effect of Pharmayod and Immunocytophyte revealed a significant increase in the gross and marketable yield of potato plants in the areas with the use of these preparations compared to with control.
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Hunter, Kendall S., Craig J. Lanning, Joseph A. Albietz, Masahiko Oka, Karen A. Fagan, Kurt R. Stenmark, and Robin Shandas. "Measurement of In-Vivo Pulmonary Vascular Impedance in Two Animal Models of Pulmonary Hypertension." In ASME 2007 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2007. http://dx.doi.org/10.1115/sbc2007-175993.

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Pulmonary vascular input impedance has been increasingly promoted as an important diagnostic for pulmonary arterial hypertension (PAH) [1,2]. The gold-standard clinical diagnostic for the disease, pulmonary vascular resistance (PVR), quantifies only the mean resistance to flow but ignores the impact of vascular stiffness and flow pulsatility, which in PAH can represent up to 40% of the total load presented to the right ventricle. PVR has also been found to be only a moderate predictor of PAH outcomes [3]. The first of these deficiencies is not present in impedance; clinical studies have found the sum of its 1st and 2nd harmonic moduli to have good correlation (r2 = 0.812) with global pulmonary vascular stiffness (PVS) [2], a hemodynamically-measured quantifier of vascular stiffness. Additionally, the 0th harmonic modulus of impedance has excellent correlation to PVR (r2 = 0.974); thus, it also quantifies the resistive load. Moreover, because PVS has recently been found as a valuable determinant of mortality in PAH [4], we believe that impedance, as a combined measure of PVR and PVS, might be an excellent predictor of disease outcomes.
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Rajesh, K., Vincent Crasta, and Gananatha Shetty. "Effect of CuO nanofiller on PVA/PVP blend." In INTERNATIONAL CONFERENCE ON MULTIFUNCTIONAL MATERIALS (ICMM-2019). AIP Publishing, 2020. http://dx.doi.org/10.1063/5.0019626.

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Kumar, B. Ranjit, S. K. Shahenoor Basha, and M. C. Rao. "Dielectric studies on PVA/PVP blend polymer electrolyte films." In 2ND INTERNATIONAL CONFERENCE ON CONDENSED MATTER AND APPLIED PHYSICS (ICC 2017). Author(s), 2018. http://dx.doi.org/10.1063/1.5032938.

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Cohn, Marvin J. "Creep Life Evaluations of ASME B31.1 Allowance for Variation From Normal Operation." In ASME 2014 Pressure Vessels and Piping Conference. American Society of Mechanical Engineers, 2014. http://dx.doi.org/10.1115/pvp2014-28468.

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The ASME B31.1-2012 Power Piping Code (Code) paras. 102.2.4, 102.3.3, and 104.8.2 provide an allowance regarding operating above the design temperature and internal pressure for short time periods. This study is an evaluation of the permitted increased life consumption associated with the above Code operating allowances for piping materials operating in the creep range. Three base metal materials are considered in this study, ASTM A335 Grades P11, P22, and P91. Two case studies were evaluated, A) 15% stress increase for 10% of the operating hours, and B) 20% stress increase for 1% of the operating hours. It was determined that these allowances increased the base metal creep rupture life consumption of Grade P11 material up to 8%, Grade P22 material up to 14%, and Grade P91 material up to 25%. Allowance A results in permitting significantly more creep damage life consumption than Allowance B. Main steam and hot reheat piping system typical operating temperatures and stresses were evaluated for these variation allowances. This study revealed that Grade P22 base metal creep damage is slightly more sensitive to stress than Grade P11 material creep rupture damage, and Grade P91 base metal creep damage is substantially more sensitive to stress than Grade P22 material creep rupture damage.
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Jha, Sushma, and Deepti Tripathi. "Dielectric and electrical study of PPy doped PVA-PVP films." In 2ND INTERNATIONAL CONFERENCE ON CONDENSED MATTER AND APPLIED PHYSICS (ICC 2017). Author(s), 2018. http://dx.doi.org/10.1063/1.5032728.

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Rao, M. C., S. K. Shahenoor Basha, and B. Ranjit Kumar. "Impedance analysis on PVA/PVP: GO blend nanocomposite polymer films." In 2ND INTERNATIONAL CONFERENCE ON CONDENSED MATTER AND APPLIED PHYSICS (ICC 2017). Author(s), 2018. http://dx.doi.org/10.1063/1.5032939.

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Hwang, In-Seol, Mi-Hwa Lee, Jung-Hyurk Lim, and Kyung-Min Kim. "Synthesis and characterization of PVP/PVA hydrogels using E-beam irradiation." In 2016 IEEE International Nanoelectronics Conference (INEC). IEEE, 2016. http://dx.doi.org/10.1109/inec.2016.7589330.

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Mahapure, Poonam D., S. W. Gosavi, and R. C. Aiyer. "Studies on PVP, PVA and their nAg composites based humidity sensors." In 2015 2nd International Symposium on Physics and Technology of Sensors (ISPTS). IEEE, 2015. http://dx.doi.org/10.1109/ispts.2015.7220108.

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Reports on the topic "PV1"

1

Kramer, K. Status Quo of PVT Characterization. Edited by Korbinian Kramer,. IEA SHC Task 60, September 2020. http://dx.doi.org/10.18777/ieashc-task60-2020-0004.

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Report B1: This report therefore aims at displaying the Status Quo of PVT Characterization in order to support PVT technology in its further development and applications. The report is hence of interest for researchers as well as public and private sector stakeholders. A key finding is that the reliability and durability of PVT modules are especially challenged at elevated temperatures and higher humidity loads. The test methods available from the IEC and ISO standards are covering the specifics of PV and ST module’s, most of which are similar for PVT modules, too.
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Ćirić, Slavica, Gordana Cvetković, Slaviša Stojković, and Slaviša Gudžić. Detection of PVY, PLRV and PVX Potato Viruses in Some Regions of Serbia. "Prof. Marin Drinov" Publishing House of Bulgarian Academy of Sciences, May 2018. http://dx.doi.org/10.7546/crabs.2018.04.17.

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Schubert, Maike, and Daniel Zenhäusern. Performance Assessment of Example PVT-Systems. IEA SHC Task 60, December 2020. http://dx.doi.org/10.18777/ieashc-task60-2020-0009.

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The performance of 26 PVT-Systems was analysed and compared in IEA-SHC Task 60. The systems are located in countries with different climatic conditions. The applications range from direct domestic hot water production and heating of public swimming pools to heat pump systems with PVT as the main heat source of the heat pump. The Key Performance Indicators (KPIs) determined for the different PVT solutions give the possibility to compare the systems despite their diversity. The goal was to show the potential of PVT collectors in different fields of application. The results show that the integration of PVT collectors in different kinds of well-dimensioned systems leads to competitive solutions, both from an energy and a financial perspective. Additionally the answers to a survey about control strategies for PVT systems, showing some main problems and possible solutions, are summarised.
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Dunigan, T. H., and N. Venugopal. Secure PVM. Office of Scientific and Technical Information (OSTI), September 1996. http://dx.doi.org/10.2172/406053.

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Lämmle, Manuel, María Herrando, and Glen Ryan. Basic concepts of PVT collector technologies, applications and markets. IEA SHC Task 60, May 2020. http://dx.doi.org/10.18777/ieashc-task60-2020-0002.

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Report D5: The aim of this report is to provide a summary of the current state of the PVT collector technologies, applications, and markets. The contents of this report have been used to update and enhance a Wikipedia article on PVT in order to better inform on PVT a wide audience. Therefore, the main structure and some literal fragments of the current Wikipedia are reused. Instead of citing the literal fragments of the old Wikipedia article in the main text, we included the old article in appendix and marked the fragments that were reused.
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Sanz, Asier`. Numerical simulation tools for PVT collectors and systems. IEA SHC Task 60, September 2020. http://dx.doi.org/10.18777/ieashc-task60-2020-0006.

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The computer-based experimentation covers almost the entire activity chain of the PVT sector. The PVT community carries out very different kind of modelling and simulation labours in order to answer to very diverse needs, such as proof-of-concepts, research, design, sizing, controlling, optimization, validation, marketing, sales, O&M, etc.
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Wang, Qiang, Anrong Wang, Zhen Li, Ernesto Sparrelid, and Torkel Brismar. Systematic review of the impact of sarcopenia on the future liver remnant growth after portal vein embolization and ALPPS. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, August 2022. http://dx.doi.org/10.37766/inplasy2022.8.0038.

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Review question / Objective: Does sarcopenia affect the future liver remnant growth after portal vein embolization/ligation (thus affect the subsequent hepatectomy in patients with liver cancers)? Condition being studied: Portal vein embolization (PVE) and Associating Liver Partition and Portal vein Ligation for Staged hepatectomy (ALPPS) are two commonly used procedures for hypertrophy of the remaining liver before major liver resection in patients with liver cancer. However, around 30% patients who undergo PVE cannot proceed to liver resection due to insufficient liver growth. Many factors may affect liver growth after PVE. This study evaluates the clinical variables affecting liver growth after portal vein embolization/ligation in patients with liver cancers.
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Resch, Alois. 2020 Subsidies for PVT collectors in selected countries. IEA SHC Task 60, July 2020. http://dx.doi.org/10.18777/ieashc-task60-2020-0005.

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Report D6: PVT collectors can be still considered as young technology, but with significant growing tendency in terms of market development and number of manufacturers on a worldwide point of view. Nevertheless, PVT is definitely in an early stage of its product life cycle, where economic competitiveness among other renewable technologies providing heat and electricity is challenging.
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Feng, Ningning, Jianbin Guan, Xing Yu, Wenhao Li, Tao Liu, Guozheng Jiang, Kaitan Yang, Yongdong Yang, and He Zhao. Jintiange Capsule May Have a Positive Effect in OVCF Patients with percutaneous vertebral augmentation: A Meta-Analysis of Randomized Trials. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, September 2022. http://dx.doi.org/10.37766/inplasy2022.9.0038.

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Review question / Objective: We aimed to conduct a meta-analysis of the effects of JTG capsules on patients with OVCF underwent PVA surgery, focusing on clinical outcomes and drug safety. Condition being studied: This meta-analysis aims to systematic evaluation of clinical efficacy and adverse effects of JTG with PVA in the treatment of osteoporotic vertebral compression fracture (OVCF).Our current evidence suggests that JTG capsule may relieve pain in OVCF patients who underwent PVA surgery, improve functional activity, and increase BMD, particularly in patients under the age of 70, as well as increase BGP levels.However, considering the unsatisfactory quality of the included trials, more high-quality trials are needed to prove this issue.
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Shankar, Natarajan. PVS Theorem Proving Enhancements. Fort Belvoir, VA: Defense Technical Information Center, June 1997. http://dx.doi.org/10.21236/ada326917.

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