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Journal articles on the topic 'Proto-oncogenes'

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Author: Grafiati

Published: 4 June 2021

Last updated: 7 July 2024

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1

Bishop, J. Michael. "Oncogenes and proto-oncogenes." Journal of Cellular Physiology 129, S4 (1986): 1–5. http://dx.doi.org/10.1002/jcp.1041290403.

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2

Montarras, D. "Proto-oncogenes." Biochimie 69, no. 3 (March 1987): 171–76. http://dx.doi.org/10.1016/0300-9084(87)90042-3.

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3

Monier, R. "PROTO-ONCOGENES ET ANTI-ONCOGENES." Reproduction Nutrition Développement 29, Suppl. 1 (1989): 49. http://dx.doi.org/10.1051/rnd:19890785.

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4

Rosen, P. "Proto-oncogenes II." Medical Hypotheses 27, no. 4 (December 1988): 289–90. http://dx.doi.org/10.1016/0306-9877(88)90009-6.

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5

Simon, M. M., G. Sliutz, and T. A. Luger. "Proto-oncogenes and oncogenes in epidermal neoplasia." Experimental Dermatology 4, no. 2 (April 1995): 65–73. http://dx.doi.org/10.1111/j.1600-0625.1995.tb00224.x.

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6

Grootegoed, J. A. "Proto-oncogenes and spermatogenesis." International Journal of Andrology 12, no. 4 (August 1989): 251–53. http://dx.doi.org/10.1111/j.1365-2605.1989.tb01311.x.

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7

Müller, Rolf. "Proto-oncogenes and differentiation." Trends in Biochemical Sciences 11, no. 3 (March 1986): 129–32. http://dx.doi.org/10.1016/0968-0004(86)90066-6.

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8

Bishop, J. Michael. "The Discovery of Proto‐oncogenes." FASEB Journal 10, no. 2 (February 1996): 362–64. http://dx.doi.org/10.1096/fasebj.10.2.8641572.

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9

Bishop, J. M., B. Drees, A. L. Katzen, T. B. Kornberg, and M. A. Simon. "Proto-oncogenes of Drosophila melanogaster." Cold Spring Harbor Symposia on Quantitative Biology 50 (January 1, 1985): 727–31. http://dx.doi.org/10.1101/sqb.1985.050.01.090.

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10

Forrester, Lesley M., Mary Brunkow, and Alan Bernstein. "Proto-oncogenes in mammalian development." Current Opinion in Genetics & Development 2, no. 1 (February 1992): 38–44. http://dx.doi.org/10.1016/s0959-437x(05)80319-3.

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11

Forrester, Lesley M., Mary Brunkow, and Alan Bernstein. "Proto-oncogenes in mammalian development." Current Biology 2, no. 2 (February 1992): 66. http://dx.doi.org/10.1016/0960-9822(92)90195-g.

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12

Shilo, Ben-Zion. "Proto-oncogenes in Drosophila melanogaster." Trends in Genetics 3 (January 1987): 69–72. http://dx.doi.org/10.1016/0168-9525(87)90178-8.

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13

Guerrero, Isabel. "Proto-oncogenes in pattern formation." Trends in Genetics 3 (January 1987): 269–71. http://dx.doi.org/10.1016/0168-9525(87)90263-0.

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14

Méchali, Marcel, Michel Gusse, Sophie Vriz, Michael Taylor, Yannick Andéol, Jacques Moreau, Jacques Hourdry, et al. "Proto-oncogenes and embryonic development." Biochimie 70, no. 7 (July 1988): 895–99. http://dx.doi.org/10.1016/0300-9084(88)90230-1.

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15

Lochter, André, Zena Werb, and MinaJ Bissell. "Matrix metaloproteases as proto-oncogenes." Matrix Biology 16, no. 2 (May 1997): 75. http://dx.doi.org/10.1016/s0945-053x(97)90093-7.

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16

Simpson, P. C. "Proto-Oncogenes and Cardiac Hypertrophy." Annual Review of Physiology 51, no. 1 (March 1989): 189–200. http://dx.doi.org/10.1146/annurev.ph.51.030189.001201.

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17

Slamon, Dennis J. "Proto-Oncogenes and Human Cancers." New England Journal of Medicine 317, no. 15 (October 8, 1987): 955–57. http://dx.doi.org/10.1056/nejm198710083171509.

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18

Matiuck, Nicholas V., and Judith L. Swain. "Proto-oncogenes and cardiac development." Trends in Cardiovascular Medicine 2, no. 2 (March 1992): 61–65. http://dx.doi.org/10.1016/1050-1738(92)90006-e.

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19

Zelenka, Peggy S. "Proto-oncogenes in cell differentiation." BioEssays 12, no. 1 (January 1990): 22–26. http://dx.doi.org/10.1002/bies.950120105.

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20

Cline, M. J., H. Battifora, and J. Yokota. "Proto-oncogene abnormalities in human breast cancer: correlations with anatomic features and clinical course of disease." Journal of Clinical Oncology 5, no. 7 (July 1987): 999–1006. http://dx.doi.org/10.1200/jco.1987.5.7.999.

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DNAs from fifty-three primary breast cancers were hybridized with 16 different proto-oncogene or oncogene probes. Abnormalities of one or more of five proto-oncogenes were found in fifty-eight percent of tumors at the time of mastectomy. Amplification of c-myc and c-erbB-2, and allelic deletions of c-ras-Ha and c-myb were the most common abnormalities. The presence of altered proto-oncogenes correlated with clinical stage of the cancers. Fifteen of 43 evaluable tumors of stages I to III recurred, and four of five evaluable stage IV tumors progressed within 16 to 24 months of surgery. All but one of the cancers that recurred or progressed had detectably altered proto-oncogenes (P less than .001). Analysis of proto-oncogenes may have prognostic value in breast cancer.

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21

Brown, Geoffrey. "Oncogenes, Proto-Oncogenes, and Lineage Restriction of Cancer Stem Cells." International Journal of Molecular Sciences 22, no. 18 (September 7, 2021): 9667. http://dx.doi.org/10.3390/ijms22189667.

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In principle, an oncogene is a cellular gene (proto-oncogene) that is dysfunctional, due to mutation and fusion with another gene or overexpression. Generally, oncogenes are viewed as deregulating cell proliferation or suppressing apoptosis in driving cancer. The cancer stem cell theory states that most, if not all, cancers are a hierarchy of cells that arises from a transformed tissue-specific stem cell. These normal counterparts generate various cell types of a tissue, which adds a new dimension to how oncogenes might lead to the anarchic behavior of cancer cells. It is that stem cells, such as hematopoietic stem cells, replenish mature cell types to meet the demands of an organism. Some oncogenes appear to deregulate this homeostatic process by restricting leukemia stem cells to a single cell lineage. This review examines whether cancer is a legacy of stem cells that lose their inherent versatility, the extent that proto-oncogenes play a role in cell lineage determination, and the role that epigenetic events play in regulating cell fate and tumorigenesis.

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22

Ransone, Lynn J., and Inder M. Verma. "Nuclear Proto-Oncogenes Fos and Jun." Annual Review of Cell Biology 6, no. 1 (November 1990): 539–57. http://dx.doi.org/10.1146/annurev.cb.06.110190.002543.

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23

TORRY, DONALD S., and GEOFFREY M. COOPER. "Proto-Oncogenes in Development and Cancer." American Journal of Reproductive Immunology 25, no. 3 (April 1991): 129–32. http://dx.doi.org/10.1111/j.1600-0897.1991.tb01080.x.

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24

TORRY, DONALD S. "Proto-Oncogenes and Germ-Cell Differentiation." American Journal of Reproductive Immunology 27, no. 3-4 (April 5, 1992): 167–70. http://dx.doi.org/10.1111/j.1600-0897.1992.tb00745.x.

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25

Ohlsson, Rolf I., and Susan B. Pfeifer-Ohlsson. "Cancer genes, proto-oncogenes, and development." Experimental Cell Research 173, no. 1 (November 1987): 1–16. http://dx.doi.org/10.1016/0014-4827(87)90327-2.

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26

Hanley, Michael R. "Proto-oncogenes in the nervous system." Neuron 1, no. 3 (May 1988): 175–82. http://dx.doi.org/10.1016/0896-6273(88)90137-7.

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27

Pollack, Pia S. "Proto-oncogenes and the Cardiovascular System." Chest 107, no. 3 (March 1995): 826–35. http://dx.doi.org/10.1378/chest.107.3.826.

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28

CHEN, H. R., and W. C. BARKER. "Nucleic Acid Sequence Database VI: Retroviral Oncogenes and Cellular Proto-Oncogenes." DNA 4, no. 2 (April 1985): 171–82. http://dx.doi.org/10.1089/dna.1985.4.171.

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29

FURUSAWA, Shunichi, Norio HAYASHI, Takashi YASHIMA, Akinori KASAHARA, Yutaka SASAKI, Michikazu KOUNO, Kazuhiro KATAYAMA, et al. "Expression of proto-oncogenes during liver regeneration." Kanzo 29, no. 3 (1988): 377–81. http://dx.doi.org/10.2957/kanzo.29.377.

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30

Bishop, J. M., A. J. Capobianco, H. J. Doyle, R. E. Finney, M. McMahon, S. M. Robbins, M. L. Samuels, and M. Vetter. "Proto-oncogenes and Plasticity in Cell Signaling." Cold Spring Harbor Symposia on Quantitative Biology 59 (January 1, 1994): 165–71. http://dx.doi.org/10.1101/sqb.1994.059.01.020.

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31

Schuchard, M. "Steroid hormone regulation of nuclear proto-oncogenes." Endocrine Reviews 14, no. 6 (December 1, 1993): 659–69. http://dx.doi.org/10.1210/er.14.6.659.

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32

SCHUCHARD, MARK, JAMES P. LANDERS, NICOLE PUNKAY SANDHU, and THOMAS C. SPELSBERG. "Steroid Hormone Regulation of Nuclear Proto-oncogenes*." Endocrine Reviews 14, no. 6 (December 1993): 659–69. http://dx.doi.org/10.1210/edrv-14-6-659.

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33

Bischof, P., K. Truong, and A. Campana. "Regulation of Trophoblastic Gelatinases by Proto-oncogenes." Placenta 24, no. 2-3 (February 2003): 155–63. http://dx.doi.org/10.1053/plac.2002.0890.

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34

Sudol, Marius. "Expression of proto-oncogenes in neural tissues." Brain Research Reviews 13, no. 4 (December 1988): 391–403. http://dx.doi.org/10.1016/0165-0173(88)90014-8.

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35

Rosen, Philip. "The significance of proto-oncogenes in carcinogenesis." Medical Hypotheses 22, no. 1 (January 1987): 23–26. http://dx.doi.org/10.1016/0306-9877(87)90004-1.

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36

Bartram, C. R. "Activation of proto-oncogenes in human leukemias." Blut 51, no. 2 (August 1985): 63–71. http://dx.doi.org/10.1007/bf00320114.

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37

Sudol, Marius. "Expression of proto-oncogenes in neural tissues." Brain Research 472, no. 4 (December 1988): 391–403. http://dx.doi.org/10.1016/0006-8993(88)91228-0.

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38

Simpson, Paul C. "Role of proto-oncogenes in myocardial hypertrophy." American Journal of Cardiology 62, no. 11 (October 1988): 13–19. http://dx.doi.org/10.1016/0002-9149(88)90026-4.

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39

Rosell, Rafael, Andrés Aguilar-Hernández, and María González-Cao. "Insights into EGFR Mutations and Oncogenic KRAS Mutations in Non-Small-Cell Lung Cancer." Cancers 15, no. 9 (April 28, 2023): 2519. http://dx.doi.org/10.3390/cancers15092519.

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40

Stasevich, Ekaterina Mikhailovna, Aksinya Nicolaevna Uvarova, Matvey Mikhailovich Murashko, Elmira Ramilevna Khabusheva, Saveliy Andreevich Sheetikov, Vladimir Sergeyevich Prassolov, Dmitriy Vladimirovich Kuprash, Denis Eriksonovich Demin, and Anton Markovich Schwartz. "Enhancer RNA AL928768.3 from the IGH Locus Regulates MYC Expression and Controls the Proliferation and Chemoresistance of Burkitt Lymphoma Cells with IGH/MYC Translocation." International Journal of Molecular Sciences 23, no. 9 (April 21, 2022): 4624. http://dx.doi.org/10.3390/ijms23094624.

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Chromosomal rearrangements leading to the relocation of proto-oncogenes into transcription-active regions are found in various types of tumors. In particular, the transfer of proto-oncogenes to the locus of heavy chains of immunoglobulins (IGH) is frequently observed in B-lymphomas. The increased expression of the MYC proto-oncogene due to IGH/MYC translocation is detected in approximately 85% of Burkitt lymphoma cases. The regulatory mechanisms affecting the oncogenes upon translocation include non-coding enhancer RNAs (eRNAs). We conducted a search for the eRNAs that may affect MYC transcription in the case of IGH/MYC translocation in Burkitt lymphoma, looking for potentially oncogenic eRNAs located at the IGH locus and predominantly expressed in B cells. Overexpression and knockdown of our primary candidate eRNA AL928768.3 led to the corresponding changes in the expression of MYC proto-oncogene in Burkitt lymphoma cells. Furthermore, we demonstrated that AL928768.3 knockdown decreased lymphoma cell proliferation and resistance to chemotherapy. Significant effects were observed only in cell lines bearing IGH/MYC abnormality but not in B-cell lines without this translocation nor primary B-cells. Our results indicate that AL928768.3 plays an important role in the development of Burkitt’s lymphoma and suggest it and similar, yet undiscovered eRNAs as potential tissue-specific targets for cancer treatment.

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41

Wu, Bin. "Expression of c-fos and c-jun proto-oncogenes by ovine preimplantation embryos." Zygote 4, no. 3 (August 1996): 211–17. http://dx.doi.org/10.1017/s0967199400003129.

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SummaryThe c-fos and c-jun proto-oncogenes are involved in the regulation of gene expression, cell proliferation, differentiation and tumorigenesis. Embryogenesis, like tumorigenesis, involves dramatic cell growth, cleavage and differentiation processes. Activation of the c-fos and c-jun proto-oncogenes in sheep conceptuses during the period of rapid growth and elongation was examined using reverse transcription and polymerase chain reaction (RT-PCR). The specificity of PCR products was determined by Southern blot hybridisation analysis with a non-radioactive DNA probe. A band corresponding to a 507 bp fragment (predicted amplified c-fos gene cDNA product) was observed in 3 of 9 day-13, 1 of 4 day-14 and 1 of 2 day-16 embryos. Meanwhile, a 400 bp c-jun transcript was aslo detected in 1 or 2 day-12, 3 of 9 day-13 and 2 of 2 day-16 embroyos. These results suggest that mRNA transcripts of c-fos and c-jun proto-oncogenes were specifically expressed during the period of ovine embryonic elongation and may have a possible role in preimplantation embryonic development of sheep.

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42

Bishop, J. Michael. "Proto-oncogenes: Clues to the puzzle of purpose." Nature 316, no. 6028 (August 1985): 483–84. http://dx.doi.org/10.1038/316483a0.

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43

Olson, Eric N. "Proto-oncogenes in the regulatory circuit for myogenesis." Seminars in Cell Biology 3, no. 2 (April 1992): 127–36. http://dx.doi.org/10.1016/s1043-4682(10)80022-4.

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44

Tetens, F., A. Kliem, G. Tscheudschilsuren, A. Navarrete Santos, and B. Fischer. "Expression of proto-oncogenes in bovine preimplantation blastocysts." Anatomy and Embryology 201, no. 5 (April 25, 2000): 349–55. http://dx.doi.org/10.1007/s004290050324.

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45

MULLER, D. "The role of proto-oncogenes in coronary restenosis." Progress in Cardiovascular Diseases 40, no. 2 (September 1997): 117–28. http://dx.doi.org/10.1016/s0033-0620(97)80004-7.

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46

Verma, I. M. "Proto-oncogenes: Role in development, growth and differentiation." Leukemia Research 10, no. 7 (January 1986): 931. http://dx.doi.org/10.1016/0145-2126(86)90325-5.

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47

Sudol, Marius, Seth G. N. Grant, and Peter C. Maisonpierre. "Proto-oncogenes and signaling processes in neural tissues." Neurochemistry International 22, no. 4 (April 1993): 369–84. http://dx.doi.org/10.1016/0197-0186(93)90019-2.

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48

Diaz, R. "Complex effects of Ras proto-oncogenes in tumorigenesis." Carcinogenesis 25, no. 4 (October 24, 2003): 535–39. http://dx.doi.org/10.1093/carcin/bgh026.

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49

Alberti, Luisella, Cristiana Carniti, Claudia Miranda, Emanuela Roccato, and Marco A. Pierotti. "RET and NTRK1 proto-oncogenes in human diseases." Journal of Cellular Physiology 195, no. 2 (March 18, 2003): 168–86. http://dx.doi.org/10.1002/jcp.10252.

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50

Peehl, Donna M. "Molecular biology of proto-oncogenes in genitourinary cancers." Cancer 60, S3 (August 1, 1987): 645–49. http://dx.doi.org/10.1002/1097-0142(19870801)60:3+<645::aid-cncr2820601534>3.0.co;2-8.

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