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Published: 11 March 2023

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1

Bekhit, Alaa El-Din A., William W. Riley, and Malik A. Hussain. Alternative Proteins. Boca Raton: CRC Press, 2021. http://dx.doi.org/10.1201/9780429299834.

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2

Watkins, Stephen. Lupins: Niche or alternative crop? Are they a viable source of home-produced GM-free protein? Market Harborough: Nuffield Farming Scholarships Trust, 2003.

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3

Adam Mariod, Abdalbasit, ed. African Edible Insects As Alternative Source of Food, Oil, Protein and Bioactive Components. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-32952-5.

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4

J, Blencowe Benjamin, and Graveley Brenton R, eds. Alternative splicing in the postgenomic era. New York: Springer Science+Business Media, 2007.

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5

Institute, Pennsylvania Bar, ed. IRS appeals process and alternative dispute resolution through fast track settlements. [Mechanicsburg, Pa.]: Pennsylvania Bar Institute, 2009.

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6

Institute, Pennsylvania Bar, ed. IRS appeals process and alternative dispute resolution through fast track settlements. [Mechanicsburg, Pa.]: Pennsylvania Bar Institute, 2009.

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7

Office, General Accounting. Tax administration: Alternative filing systems : report to the Chairman, Subcommittee on Treasury, Postal Service, and General Government, Committee on Appropriations, House of Representatives. Washington, D.C: The Office, 1996.

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8

Office, General Accounting. Tax administration: Potential impact of alternative taxes on taxpayers and administrators : report to the Chairmen and ranking minority Members, Committee on Finance, U.S. Senate and Committee on Ways and Means, House of Representatives. Washington, D.C. (P.O. Box 37050, Washington, D.C. 20013): The Office, 1998.

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9

1973-, Lappé Anna, ed. Hope's edge: The next diet for a small planet. New York: Jeremy P. Tarcher/Putnam, 2002.

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10

1973-, Lappé Anna, ed. Hope's edge: The next diet for a small planet. New York: Jeremy P. Tarcher/Putnam, 2003.

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11

Alternative Proteins. Taylor & Francis Group, 2021.

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12

Divan, Aysha, and Janice A. Royds. 4. Proteins. Oxford University Press, 2016. http://dx.doi.org/10.1093/actrade/9780198723882.003.0004.

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Biological functions require protein and the protein makeup of a cell determines its behaviour and identity. Proteins, therefore, are the most abundant molecules in the body except for water. The approximately 20,000 protein coding genes in the human genome can, by alternative splicing, multiple translation starts, and post-translational modifications, produce over 1,000,000 different proteins, collectively called ‘the proteome’. It is the size of the proteome and not the genome that defines the complexity of an organism. ‘Proteins’ describes the composition and structure of proteins and how they are studied. What information is required in order to understand how proteins work and what happens when this function is impaired in disease?
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13

Lindberg, Jan Erik, Gunnar Lindberg, Jukka Teräs, Gert Poulsen, Svein Øivind Solberg, Knud Tybirk, Joanna Przedrzymirska, et al. Nordic Alternative Protein Potentials. Nordic Council of Ministers, 2016. http://dx.doi.org/10.6027/tn2016-527.

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14

Emerging Sources and Applications of Alternative Proteins. Elsevier, 2022. http://dx.doi.org/10.1016/s1043-4526(22)x0004-1.

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15

Bekhit, Alaa El-Din A., William W. Riley, and Malik A. Hussain. Alternative Proteins: Safety and Food Security Considerations. Taylor & Francis Group, 2021.

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16

Bekhit, Alaa El-Din A., William W. Riley, and Malik A. Hussain. Alternative Proteins: Safety and Food Security Considerations. Taylor & Francis Group, 2021.

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17

Bekhit, Alaa El-Din A., William W. Riley, and Malik A. Hussain. Alternative Proteins: Safety and Food Security Considerations. Taylor & Francis Group, 2021.

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18

(Editor), Chhorn Lim, Carl D. Webster (Editor), and Cheng-Sheng (Editor), eds. Alternative Protein Sources in Aquaculture Diets. Haworth Food & Agricultural Products Press, 2008.

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19

Lee, Cheng-Sheng, Carl D. Webster, and Chhorn Lim. Alternative Protein Sources in Aquaculture Diets. Taylor & Francis Group, 2019.

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20

Green, Peter, Kanti Mardia, Vysaul Nyirongo, and Yann Ruffieux. Bayesian modelling for matching and alignment of biomolecules. Edited by Anthony O'Hagan and Mike West. Oxford University Press, 2018. http://dx.doi.org/10.1093/oxfordhb/9780198703174.013.2.

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This article describes Bayesian modelling for matching and alignment of biomolecules. One particular task where statistical modelling and inference can be useful in scientific understanding of protein structure is that of matching and alignment of two or more proteins. In this regard, statistical shape analysis potentially has something to offer in solving biomolecule matching and alignment problems. The article discusses the use of Bayesian methods for shape analysis to assist with understanding the three-dimensional structure of protein molecules, with a focus on the problem of matching instances of the same structure in the CoMFA (Comparative Molecular Field Analysis) database of steroid molecules. It introduces a Bayesian hierarchical model for pairwise matching and for alignment of multiple configurations before concluding with an overview of some advantages of the Bayesian approach to problems in protein bioinformatics, along with modelling and computation issues, alternative approaches, and directions for future research.
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21

Lei, Xingen. Seaweed and Microalgae As Alternative Sources of Protein. Burleigh Dodds Science Publishing Limited, 2021.

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22

Lei, Xin Gen, ed. Seaweed and microalgae as alternative sources of protein. Burleigh Dodds Science Publishing, 2021. http://dx.doi.org/10.19103/as.2021.0091.

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23

Lei, Xin, Charlotte Jacobsen, Sung-woo Kim, and Gaozhing Shen. Seaweed and Microalgae As Alternative Sources of Protein. Burleigh Dodds Science Publishing Limited, 2021.

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24

Lei, Xingen. Seaweed and Microalgae As Alternative Sources of Protein. Burleigh Dodds Science Publishing Limited, 2021.

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25

Lei, Xingen. Seaweed and Microalgae As Alternative Sources of Protein. Burleigh Dodds Science Publishing Limited, 2021.

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26

Atlas, Nava. Plant-Powered Protein: 125 Recipes for Using Today's Amazing Meat Alternatives. Grand Central Publishing, 2020.

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27

Plant-Powered Protein: 125 Recipes for Using Today's Amazing Meat Alternatives. Grand Central Publishing, 2020.

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28

Atlas, Nava. Plant-Powered Protein: 125 Recipes for Using Today's Amazing Meat Alternatives. Grand Central Publishing, 2020.

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29

Agatha, Donald. Heart Healthy Cookbook: High Protein Recipes for Breakfast, Lunch, Dinner and Snacks - Vegan Protein Alternatives for Athletes and Runners. Independently Published, 2022.

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30

Boero, Mauro, and Masaru Tateno. Quantum-theoretical approaches to proteins and nucleic acids. Edited by A. V. Narlikar and Y. Y. Fu. Oxford University Press, 2017. http://dx.doi.org/10.1093/oxfordhb/9780199533046.013.17.

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This article describes quantum methods used to study proteins and nucleic acids: Hartree–Fock all-electron approaches, density-functional theory approaches, and hybrid quantum-mechanics/molecular-mechanics approaches. In addition to an analysis of the electronic structure, quantum-mechanical approaches for simulating proteins and nucleic acids can elucidate the cleavage and formation of chemical bonds in biochemical reactions. This presents a computational challenge, and a number of methods have been proposed to overcome this difficulty, including enhanced temperature methods such as high-temperature molecular dynamics, parallel tempering and replica exchange. Alternative methods not relying on the knowledge a priori of the final products make use of biasing potentials to push the initial system away from its local minimum and to enhance the sampling of the free-energy landscape. This article considers two of these biasing techniques, namely Blue Moon and metadynamics.
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31

Hwang, Joseph Bumsuh. Effect of alternative glycosylation on insulin receptor processing in 3T3-L1 adipocytes. 1999.

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32

Mariod, Abdalbasit Adam. African Edible Insects As Alternative Source of Food, Oil, Protein and Bioactive Components. Springer International Publishing AG, 2021.

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33

Mariod, Abdalbasit Adam. African Edible Insects As Alternative Source of Food, Oil, Protein and Bioactive Components. Springer, 2020.

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34

Lei, Peng, Scott Ayton, and Ashley I. Bush. Metal-Protein Attenuating Compounds in Neurodegenerative Diseases. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780190233563.003.0015.

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Neurodegenerative disorders including Alzheimer’s (AD), Parkinson’s disease (PD), Huntington’s disease (HD), and amyotrophic lateral sclerosis (ALS) are progressive diseases of the aging population with currently few therapeutic options. While aggregation and deposition of disease-specific proteins link the pathologies of these diseases, targeting these aggregating proteins with therapeutics has not yet been successful in clinical trial. This chapter profiles metals (copper, zinc, and iron) as alternative drug targets for neurodegeneration. Complex changes to metals occur in these neurodegenerative diseases. Accumulating evidences have demonstrated that perturbations to metal homeostasis contribute to the progression of neuronal dysfunction and death. Importantly, several phase II trials have shown that correcting metal dyshomeostasis improves clinical outcomes; the chapter argues that it is now time to explore the therapeutic utility of metal-based drugs in larger, phase III trials.
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35

Schadt, Eric E. Network Methods for Elucidating the Complexity of Common Human Diseases. Edited by Dennis S. Charney, Eric J. Nestler, Pamela Sklar, and Joseph D. Buxbaum. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190681425.003.0002.

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The life sciences are now a significant contributor to the ever expanding digital universe of data, and stand poised to lead in both the generation of big data and the realization of dramatic benefit from it. We can now score variations in DNA across whole genomes; RNA levels and alternative isoforms, metabolite levels, protein levels, and protein state information across the transcriptome, metabolome and proteome; methylation status across the methylome; and construct extensive protein–protein and protein–DNA interaction maps, all in a comprehensive fashion and at the scale of populations of individuals. This chapter describes a number of analytical approaches aimed at inferring causal relationships among variables in very large-scale datasets by leveraging DNA variation as a systematic perturbation source. The causal inference procedures are also demonstrated to enhance the ability to reconstruct truly predictive, probabilistic causal gene networks that reflect the biological processes underlying complex phenotypes like disease.
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36

Puntis, John. Formula and complementary feeding. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198759928.003.0005.

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Some mothers are unable, or choose not, to breastfeed; bottle-feeding carries certain risks that can be minimized by following simple rules. Formula must satisfy all the nutritional needs of an infant and recommendations for the composition of infant formula have been adopted in the Codex Alimentarius. The two main types of formula differ in protein composition (whey or casein predominant). Follow-on formula are designed for infants from 6–12 months of age. Soy protein is an alternative to cow milk protein, but because of its high phytoestrogen content, should not be used before 6 months. Unmodified cow’s milk as the main drink before 12 months of age is associated with iron deficiency. ‘Complementary feeding’ embraces all solid and liquid feeds other than breast milk and infant formula. There is considerable international variation in practice with regard to introduction of complementary feeds, but in general this should not be before 17 weeks, and not after 26 weeks.
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37

Aquaculture and By-Products: Challenges and Opportunities in the Use of Alternative Protein Sources and Bioactive Compounds. Elsevier, 2020. http://dx.doi.org/10.1016/s1043-4526(20)x0003-9.

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38

Knorre, Dmitri G. Affinity Modification of Biopolymers. Taylor & Francis Group, 2018.

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39

Knorre, Dmitri G. Affinity Modification of Biopolymers. Taylor & Francis Group, 2018.

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40

Affinity Modification of Biopolymers. Taylor & Francis Group, 2017.

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41

Knorre, Dmitri G. Affinity Modification of Biopolymers. Taylor & Francis Group, 2018.

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42

Medjeral-Thomas, Nicholas, Anna Richards, and Matthew C. Pickering. Molecular basis of complement-mediated renal disease. Edited by Neil Turner. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199592548.003.0333.

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Abnormal regulation of complement is intimately associated with C3 glomerulopathy and atypical haemolytic uraemic syndrome. Atypical haemolytic uraemic syndrome is characterized by renal thrombotic microangiopathy due to an inability to regulate complement activation along the renal endothelium. The development of thrombosis is critically dependent on the ability to activate C5. Eculizumab, a monoclonal anti-C5 antibody, is an effective therapy for this condition. C3 glomerulopathy refers to glomerular lesions characterized by accumulation of C3 in the absence of immunoglobulin. The prototypic example is dense deposit disease. This condition is associated with impaired regulation of the alternative pathway in plasma. In other subtypes of C3 glomerulopathy, familial studies have identified mutations within the complement factor H-related protein family. Polymorphic variation within this protein family also influences susceptibility to IgA nephropathy. The mechanism underlying these associations remains unknown and is the subject of ongoing research efforts.
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43

Chowdhury, Arjun. The Self-Undermining State. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780190686710.003.0002.

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This chapter provides an informal rationalist model of state formation as an exchange between a central authority and a population. In the model, the central authority protects the population against external threats and the population disarms and pays taxes. The model specifies the conditions under which the exchange is self-enforcing, meaning that the parties prefer the exchange to alternative courses of action. These conditions—costly but winnable interstate war—are historically rare, and the cost of such wars can rise beyond the population’s willingness to sacrifice. At this point, the population prefers to avoid war rather than fight it and may prefer an alternative institution to the state if that institution can prevent war and reduce the level of extraction. Thus the modern centralized state is self-undermining rather than self-enforcing. A final section addresses alternative explanations for state formation.
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44

Moonesinghe, Ramini, and Sue Mallett. Acute pain in patients with renal or hepatic impairment. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780199234721.003.0015.

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The metabolism and excretion of many analgesic drugs will be altered in the presence of renal or hepatic impairment. Some analgesic drugs can cause renal or hepatic damage. Protein binding of drugs may be altered by hepatic reduction in production or uraemic displacement from binding sites. In renal disease, paracetamol is the simple analgesic of choice. Morphine can be used with care in mild to moderate renal disease, but fentanyl or oxycodone may be better alternatives. Non-steroidal anti-inflammatory drugs should be avoided in renal disease. In hepatic disease with significant impairment, doses of morphine must be reduced and the dosage interval lengthened. Fentanyl should be avoided in severe hepatic disease.
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45

JARRETT, Kimberly. There Is No Protein in Mashed Potato Dr Younan Dr Now Journal Notebook / Greeting Card Alternative / 130 Pages 8. 5''x11'. Independently Published, 2021.

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46

Osbert Cotta, Menino, and Jason Roberts. Pharmacokinetic and pharmacodynamic principles of antimicrobials. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198758792.003.0009.

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The continual threat of antimicrobial resistance means that optimizing current antimicrobial therapy is of paramount importance. Antimicrobial pharmacokinetics and pharmacodynamics (PK/PD) play a central role in developing dosing regimens that target maximal clinical outcomes and microbiological eradication. This chapter describes the three main PK/PD indices into which current antimicrobials are categorized. Elements of PK that require due consideration when optimizing antimicrobial therapy, including volume of distribution, antimicrobial clearance, and protein binding, are also discussed. Finally, specific attention is paid to antimicrobial dosing among challenging populations, namely the critically ill and obese, and the potential role of alternative dosing strategies, such as use of loading doses and extended/continuous infusions, is also outlined.
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47

Mozer, Anthony B., Konstantinos Spaniolas, and Walter J. Pories. Nutritional Deficiencies and Bariatric Surgery. Edited by Tomasz Rogula, Philip Schauer, and Tammy Fouse. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190608347.003.0014.

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Dietary intolerance and poor oral intake account for a disproportionate number of emergency department visits and readmissions after bariatric surgery. Micronutrient, vitamin, and protein deficiencies can occur after both malabsorptive and restrictive weight-loss operations, and they are best mitigated against by conscientious preoperative counseling and vigilance in follow-up. Routine vitamin supplementation can prevent the need for unnecessary laboratory testing, while symptoms of dumping syndrome can frequently be managed with dietary and behavioral modification alone. Alternative enteral feeding access for alimentary supplementation can be safely performed surgically or with assistance by interventional radiology, and should be considered in the management of perforation, early anastomotic leak, surgical revision, or patients with refractory malnourishment.
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48

Banjara, Manoj, and Damir Janigro. Effects of the Ketogenic Diet on the Blood-Brain Barrier. Edited by Detlev Boison. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780190497996.003.0030.

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Ketone bodies (KBs) are always present in the blood, and their levels increase after high-fat diet intake, prolonged exercise, or extended fasting. Thus, one can predict effects on the brain capillary endothelium from high levels of ketones in the blood. Prolonged exposure of blood-brain barrier (BBB) endothelial cells to KBs induces expression of monocarboxylate transporters and enhances brain uptake of KBs. In addition, cell migration and expression of gap junction proteins are up-regulated by KBs. Thus, beneficial effects of the ketogenic diet may depend on increased brain uptake of KBs to match metabolic demand and repair of a disrupted BBB. As the effects of KBs on the BBB and their transport mechanisms across the BBB are better understood, it will be possible to develop alternative strategies to optimize the therapeutic benefits of KBs for brain disorders where the BBB is compromised.
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49

Hum, Gabriel. Novel approaches towards the synthesis of protein tyrosine phosphatase inhibitors and alternative strategies in the design of transition state analogues for phosphatase abzymes. 2002.

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50

LATHAN, Lawrence. High Protein Cookbook: Rapid Remedy Guide and Recipes on Food Nutrients, Diet, Supplements, Vitamins, Smoothies, Alternatives, Risk and Benefits on Diet Goals for Improvement Lifestyle. Independently Published, 2022.

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