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1

R, Bevan David, and MES Medical Education Services (Canada), eds. New horizons in anaesthesia: Focus on propofol : proceedings of a symposium held in Ottawa, Canada, June 9, 1989. Oxford: MEDICINE Publishing Foundation, 1989.

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2

Killian, Aaron. Potential advantages associated with propofol anesthesia in outpatient surgical procedures. [Ottawa: Ottawa General Hospital[, 1991.

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3

Bonn, Universität, ed. Einfluss von Propofol auf Parameter der zellulären Immunität. [s.l.]: [s.n.], 1993.

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4

Schüttler, Jürgen. Pharmakokinetik und -dynamik des intravenösen Anaesthetikums Propofol (Disoprivan®). Berlin, Heidelberg: Springer Berlin Heidelberg, 1990. http://dx.doi.org/10.1007/978-3-642-46706-6.

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5

McAdam, Laura Catherine. Propofol and benzodiazepine modulation of GABA[subscript]AR function. Ottawa: National Library of Canada = Bibliothèque nationale du Canada, 1999.

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6

Magathan, Jose G. Propofol: A new intravenous anaesthetic agent : a review of the literature. [Toronto: Faculty of Dentistry, University of Toronto], 1992.

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7

D'Aguiam, George. Propofol as the sole intravenous agent for conscious sedation in dentistry. [Toronto: Faculty of Dentistry, University of Toronto], 1994.

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8

Ahmad, Iftikhar. Pro and anticonvulsant activity of opioid analgesics and their interaction with propofol. Manchester: University of Manchester, 1994.

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9

Lang, Tatjana. Narkose bei Schildkröten unter besonderer Berücksichtigung von Propofol und Isofluran: Eine klinische Studie. München: Hieronymus, 2002.

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10

Scheel, Andrea. Aufbau, Evaluierung und Anwendung sensitiver und spezifischer Methoden zur Bestimmung von Propofol und Propofolchinon in biologischen Flüssigkeiten mittels Hochleistungs-Flüssigkeitschromatographie. Lübeck: Zentrale Hochschulbibliothek Lübeck, 2011.

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11

Weeger, Cordula. Narkose bei Echsen und Schlangen unter der besonderen Berücksichtigung der Anwendung von Propofol, Isofluran und der Kombination dieser Anästhetika: Eine klinische Studie. München: Hieronymus, 2002.

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12

Teuteberg, Tilman F. K. Einfluss der chirurgischen Stimulation auf die mittleren Komponenten der somatosensorisch evozierten Potentiale unter Alfentanil-Propofol-Anaesthesie: Untersuchungen zu klinischen und elektrophysiologischen Arousal-Phaenomenen. [s.l.]: [s.n.], 1997.

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13

John, Maloney. Proposal. Cambridge, Mass: Zoland Books, 1999.

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14

Scottish National Photography Centre. Action Committee. Proposal. [Edinburgh]: [SNPC], 2002.

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15

Pharmakokinetik Dynam Propofol. Springer-Verlag, 1990.

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16

Lane, Gordon G. An evaluation of propofol use. 1992.

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17

Gottschlich, Christina. Propofol - TIVA bei gynäkologischen Operationen. 1994.

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18

Dertwinkel, Roman. Propofol zur kontinuierlichen Sedierung bei Periduralanästhesie. 1989.

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19

Jensen, Anders Gadegaard. Clinical and laboratory studies on propofol. Linkoping University, 1993.

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20

Kibelbek, Michael J., and Lori A. Aronson. Egg and Soy Allergies and Propofol Use. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199764495.003.0011.

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Pediatric gastroenterologists are increasingly requesting the services of anesthesiologists for the comfort, safety, and peace of mind of their patients and their families. Although outpatient endoscopic procedures are usually brief, these patients often have histories of reflux, multiple drug and food allergies, and delayed gastric emptying.
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21

Kibelbek, Michael J., Lori A. Aronson, and Lisa D. Heyden. Egg and Soy Allergies and Propofol Use. Edited by Erin S. Williams, Olutoyin A. Olutoye, Catherine P. Seipel, and Titilopemi A. O. Aina. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190678333.003.0010.

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Anesthesiologists and sedationists often use propofol as the main anesthetic agent for brief procedures, such as esophagogastroduodenoscopy with biopsy for eosinophilic esophagitis (EoE). Pediatric patients presenting for endoscopy often have a history of reflux as well as drug and food allergies. Specifically, patients with EoE often have sensitivity to egg and soy, as well as milk and dairy products, tree nuts/peanuts, and seafood (fish/shellfish). Propofol use is often cited as a contraindication in patients with hypersensitivity to egg and soy. Current literature does not support avoiding propofol in egg- and soy-allergic patients. Most practitioners, however, continue to avoid propofol in patients with a history of egg anaphylaxis due to lack of evidence supporting its safe use in this population.
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22

C, Deeprose, ed. Unconscious learning during surgery with propofol anaesthesia. 2004.

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23

Laschat, Michael. Propofol im Vergleich zu Etomidat zur Narkoseeinleitung. 1989.

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24

Propofol: Pharmacokinetics, Medical Uses and Potential Health Effects. Nova Science Pub Inc, 2014.

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25

Konighaus, Hilke. Anasthesiologische und sonographische Evaluierung des Einflusses von Metamizol/Propofol und Fentanyl/Propofol auf die Vasoaktivitat und Hamodynamik beim Kaninchen. 2007.

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26

Jennen, Brigitte. Klinische Pharmakokinetik von Propofol (Disoprivan), einem neuen intravenösen Hypnotikum. [s.l.], 1988.

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27

Maxerath, Michael Theodor. Psychometrische Untersuchungen in der unmittelbaren und späten postnarkotischen Phase nach totaler intravenöser Anästhesie mit Propofol und Alfentanil versus Propofol und Ketamin. 1992.

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28

Glinski, Eckard von. Analgosedierung von schädelhirntraumatisierten Patienten: Methodhexital (Brevimytal) ; Fentanyl und Propofol ; Fentanyl. 1991.

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29

Lin, Li Alison. Modulating propofol anesthesia and hepatotoxicity with monoterpene alcohols: Molecular basis. 2004.

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30

Hammas, Bengt. Experimental and Clinical Studies on the Antiemetic Effects of Propofol. Uppsala Universitet, 2001.

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31

Jardorf, Matthias. Pharmakodynamische Untersuchungen mit dem Hypnotikum Propofol bei intravenöser Infusion und Bolusapplikation. [s.l.], 1988.

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32

Raps, Michael Otto Walter. Propofol und Etomidate zur Narkoseeinleitung: Eine klinische Studie mit Cortisol und ACTH Bestimmung und der Einfluss von Propofol auf endokrinologische Parameter unter Ruhe- und unter Stressbedingungen. München, 1987.

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33

Schüttler, Jürgen. Pharmakokinetik und -Dynamik des Intravenösen Anaesthetikums Propofol: Grundlagen Für eine Optimierte Dosierung. Springer London, Limited, 2013.

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34

Orser, Beverley A. Propofol (2,6 di-isopropylphenol) modulation of excitatory and inhibitory amino acid receptors. 1995.

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35

Schüttler, Jürgen. Pharmakokinetik und -dynamik des intravenösen Anaesthetikums Propofol: Grundlagen für eine optimierte Dosierung. Springer, 1990.

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36

John, Susan. The use of propofol as a sedative agent in critically ill neurologic patients. 1997.

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37

Krätz, Anna Livia. Zum Einfluss der intravenösen Hypnotika Thiopental, Etomidate und Propofol auf das QT-Intervall. 1997.

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38

The Effects of Gender on Receovery Times Following General Anesthesia with Propofol and Sevoflurane. Storming Media, 2003.

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39

Bonn, Universität, ed. Bestimmung der Blut-Gewebeverteilungskoeffizienten von Propofol in periphervenösem Blut und grauer und weisser Hirnsubstanz. 1997.

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40

Singh, Stancy. A drug utilization evaluation of propofol as a sedating agent in the intensive care unit. 1997.

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41

I Put the Pro in Propofol: Funny Anesthesiologist Idea with Funny Saying on Cover, Coworkers. Independently Published, 2021.

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42

Lacombe, Gabriel F. Comparison of remifentanil infusion with fentanyl for use with propofol for deep sedation in oral surgery. 2003, 2003.

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43

Absalom, Anthony, and John Sear. Intravenous anaesthetics. Edited by Michel M. R. F. Struys. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199642045.003.0015.

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In recent decades, increasing attention has been focused on the intravenous anaesthetic agents. This interest has been stimulated by the discovery and availability of agents with increasingly favourable pharmacokinetic and dynamic properties, coupled with advances in knowledge of pharmacology and advances in computer technology. For most patients and operative procedures, anaesthesia is induced with a bolus or fast infusion of a short-acting drug, most commonly propofol. Increasingly, anaesthesia is thereafter also maintained with an infusion of an agent with favourable kinetics, again usually of propofol, commonly supplemented with boluses or infusions of opioids. Propofol is also commonly used for procedural and intensive care sedation. It has highly favourable pharmacokinetics and pharmacodynamics for these applications as sedative or hypnotic agent—rapid, smooth onset, minimal accumulation, and rapid smooth offset of effect—but is by no means an ideal agent. In some specific situations, such as when its haemodynamic or respiratory effects are detrimental, use of alternative agents such as ketamine and etomidate are warranted. All the currently available agents have adverse effects, some of which are related to the active compound and some of which are related to the vehicle. Efforts are thus being made to develop new formulations, with fewer adverse effects, and to develop newer and better drugs. In the future we are also likely to see increasing use of older agents, but for newer indications (such as the use of ketamine as an antidepressant).
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44

Gutenberg-Universität, Johannes, ed. Einfluss von Alter der Patienten und Infusionszeiten auf Einschlaf- und Aufwachzeiten nach Sedierung mit Propofol bei Regionalanästhesien. 1989.

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45

Gesekus, Anne Susan. Untersuchungen zur Vigilanz von Kindern nach ambulanter Anaesthesie: Totale intravenöse Anaesthesie (Propofol/Alfentanil) versus Inhalationsanaesthesie (Isofluran/N2O). 1993.

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46

Kokabpick, Sepideh. Effektivität und Sicherheit der Sedierung mit Propofol bei der ERCP: Eine prospektive, kontrollierte klinische und manometrische Studie. 2000.

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47

Kiel, Universität, ed. Influence of propofol and modeate hypothermia on bispectral index, satate and response entropy during coronary artery bypass grafting. 2004.

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48

Fudickar, Wolfgang. Die Messung der operativen Stressreaktion mit dem Verfahren der Herzfrequenzvariabiliät- Spektralanalyse: Während einer Allgemeinanästhesie mit Propofol und Sevofluran. 2004.

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49

Prout, Jeremy, Tanya Jones, and Daniel Martin. General therapeutics. Oxford University Press, 2014. http://dx.doi.org/10.1093/med/9780199609956.003.0007.

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Drugs used during the perioperative period may have implications for both the patient and the environment. Drugs may cause toxicity such as propofol infusion syndrome or dependency problems in the long-term. Perioperative anaphylaxis, the triggers, recognition and management is detailed. Management of patients with acute poisoning is included with general assessment and supportive management as well as specific antidotes. The clinical consequences of paracetamol poisoning are discussed in detail.
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50

Gutenberg-Universität, Johannes, ed. Qualität des intraoperativen Schlafes und der postoperativen Erholung unter einer Kombination aus Totaler Intraveöser Anästhesie mittels Propofol und Katheter-Epiduralanästhesie. 1995.

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