Relevant bibliographies by topics / Propionate

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Academic literature on the topic 'Propionate'

Author: Grafiati
Published: 4 June 2021
Last updated: 29 January 2023

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Journal articles on the topic "Propionate"

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Mirnaya, T. A., G. G. Yaremchuk, and S. V. Volkov. "Phase Diagrams of Binary Systems of Some Alkali Propionates." Zeitschrift für Naturforschung A 48, no. 10 (October 1, 1993): 995–99. http://dx.doi.org/10.1515/zna-1993-1006.

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Abstract The phase diagrams of the binary systems sodium-potassium, sodium-caesium, and potassium-caesium propionates have been investigated by differential thermal analysis and hot-stage polarization microscopy. Smectic liquid crystals in the systems with sodium propionate have been discovered. Liquid crystal formation in binaries of two non-mesomorphic components is explained by latent mesomorphism which is shown to be inherent to both sodium and potassium propionate.
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Deacon, Glen B., Peter C. Junk, Winnie W. Lee, Maria Forsyth, and Jun Wang. "Rare earth 3-(4′-hydroxyphenyl)propionate complexes." New Journal of Chemistry 39, no. 10 (2015): 7688–95. http://dx.doi.org/10.1039/c5nj00787a.

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Structural variation of lanthanoid 3-(4′-hydroxyphenyl)propionates and investigation of the anti-corrosion properties of lanthanum 3-(4′-hydroxyphenyl)propionate are presented, highlighting lanthanoid contraction and the importance of the –CHCH− structural unit of 4-hydroxycinnamates in corrosion mitigation.
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Sebastiani, Federico, Chiara Baroni, Gaurav Patil, Andrea Dali, Maurizio Becucci, Stefan Hofbauer, and Giulietta Smulevich. "The Role of the Hydrogen Bond Network in Maintaining Heme Pocket Stability and Protein Function Specificity of C. diphtheriae Coproheme Decarboxylase." Biomolecules 13, no. 2 (January 25, 2023): 235. http://dx.doi.org/10.3390/biom13020235.

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Monoderm bacteria accumulate heme b via the coproporphyrin-dependent biosynthesis pathway. In the final step, in the presence of two molecules of H2O2, the propionate groups of coproheme at positions 2 and 4 are decarboxylated to form vinyl groups by coproheme decarboxylase (ChdC), in a stepwise process. Decarboxylation of propionate 2 produces an intermediate that rotates by 90° inside the protein pocket, bringing propionate 4 near the catalytic tyrosine, to allow the second decarboxylation step. The active site of ChdCs is stabilized by an extensive H-bond network involving water molecules, specific amino acid residues, and the propionate groups of the porphyrin. To evaluate the role of these H-bonds in the pocket stability and enzyme functionality, we characterized, via resonance Raman and electronic absorption spectroscopies, single and double mutants of the actinobacterial pathogen Corynebacterium diphtheriae ChdC complexed with coproheme and heme b. The selective elimination of the H-bond interactions between propionates 2, 4, 6, and 7 and the polar residues of the pocket allowed us to establish the role of each H-bond in the catalytic reaction and to follow the changes in the interactions from the substrate to the product.
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Hayashi, Takashi, Hideaki Sato, Takashi Matsuo, Takaaki Matsuda, Yutaka Hitomi, and Yoshio Hisaeda. "Enhancement of enzymatic activity for myoglobins by modification of heme-propionate side chains." Journal of Porphyrins and Phthalocyanines 08, no. 03 (March 2004): 255–64. http://dx.doi.org/10.1142/s1088424604000246.

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The modification of myoglobin is an attractive process not only for understanding its molecular mechanism but also for engineering the protein function. The strategy of myoglobin functionalization can be divided into at least two approaches: site-directed mutagenesis and reconstitution with a non-natural prosthetic group. The former method enables us to mainly modulate the physiological function, while the latter has the advantage of introducing a new function on the protein. Particularly, replacement of the native hemin with an artificially created hemin having hydrophobic moieties at the terminal of the heme-propionate side chains serves as an appropriate substrate-binding site near the heme pocket, and consequently enhances the peroxidase and peroxygenase activities for the reconstituted myoglobin. In addition, the incorporation of the synthetic hemin bearing modified heme-propionates into an appropriate apomyoglobin mutant drastically enhances the peroxidase activity. In contrast, to convert myoglobin into a cytochrome P450 enzyme, a flavin moiety as an electron transfer mediator was introduced at the terminal of the heme-propionate side chain. The flavomyoglobin catalyzes the deformylation of 2-phenylpropanal in the presence of NADH under aerobic conditions through the peroxoanion formation from the oxygenated species. In addition, modification of the heme-propionate side chains has an significant influence on regulating the reactivity of the horseradish peroxidase. Furthermore, the heme-propionate side chain can form a metal binding site with a carboxylate residue in the heme pocket. These studies indicate that modification of the heme-propionate side chains can be a new and effective way to engineer functions for the hemoproteins.
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&NA;. "Fluticasone propionate." Reactions Weekly &NA;, no. 1379 (November 2011): 19. http://dx.doi.org/10.2165/00128415-201113790-00068.

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&NA;. "Fluticasone propionate." Reactions Weekly &NA;, no. 1384 (January 2012): 27. http://dx.doi.org/10.2165/00128415-201213840-00108.

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&NA;. "Fluticasone propionate." Reactions Weekly &NA;, no. 708 (July 1998): 6. http://dx.doi.org/10.2165/00128415-199807080-00015.

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&NA;. "Fluticasone propionate." Reactions Weekly &NA;, no. 730 (December 1998): 7. http://dx.doi.org/10.2165/00128415-199807300-00023.

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&NA;. "Fluticasone propionate." Reactions Weekly &NA;, no. 731 (December 1998): 7. http://dx.doi.org/10.2165/00128415-199807310-00019.

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&NA;. "Fluticasone propionate." Reactions Weekly &NA;, no. 742 (March 1999): 8–9. http://dx.doi.org/10.2165/00128415-199907420-00021.

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Dissertations / Theses on the topic "Propionate"

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Oliveira, Gabriela Bagio. "Frequência de fornecimento de narasina na nutrição de ovinos." Universidade de São Paulo, 2018. http://www.teses.usp.br/teses/disponiveis/10/10135/tde-03122018-113419/.

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O consumo na dose correta e principalmente na frequência adequada são as principais dificuldades do fornecimento de ionóforos para animais em dietas com elevado teor de volumoso. O objetivo do estudo foi avaliar o efeito da frequência do fornecimento de narasina no desempenho (Exp. I), parâmetros de fermentação ruminal, digestibilidade aparente dos nutrientes e balanço de nitrogênio (Exp. II) em ovinos alimentados com dietas contendo elevado teor de volumoso. As dietas experimentais foram compostas por 95% de feno de coastcros e 5% de milho moído. Os tratamentos utilizados foram: Controle (C): fornecimento do concentrado uma vez ao dia sem ionóforo, Narasina 24 horas (N24): fornecimento diário de narasina na dosagem de 13 mg de narasina /kg de MS, Narasina 48 horas (N48): fornecimento de narasina a cada 48 horas (dias alternados), sendo no primeiro dia ofertado 26 mg de narasina/kg de MS e no segundo dia foi fornecido apenas o milho moído (média receberam 13 mg de narasina/kg de MS), Narasina 72 horas (N72): fornecimento de narasina a cada 72 horas, sendo no primeiro dia ofertado 39 mg de narasina/kg de MS, já no segundo e terceiro dia fornecido apenas o milho moído sem ionóforo. As análises estatísticas foram realizadas utilizando o procedimento MIXED do SAS (2002) e considerado efeito significativo quando P 0,05. Experimento I: Foram utilizados 44 cordeiros (33,31 ± 0,59 kg), sendo o delineamento experimental de blocos completos casualizados, com a duração de 105 dias. Não houve efeito para o CMS (P = 0,28), no entanto, a inclusão de narasina diariamente (N24) e a cada 48 horas (N48) aumentou o GMD dos animais (P = 0,03) e a EA (P = 0,02). Experimento II: Foram utilizados quatro borregos (Dorper x Santa Inês, castrados e providos de cânulas ruminais). O delineamento experimental utilizado foi o quadrado latino 4 x 4. O experimento teve duração total de 144 dias, divididos em quatro períodos de trinta e seis dias. Em cada período os doze primeiros dias foram utilizados como wash-out, do 13° ao 36° dia os animais receberam as dietas experimentais, a colheitas de dados (total de fezes, urina e de fluido ruminal) foram realizadas nos seis últimos dias de cada período. Não houve efeito na digestibilidade da MS e do FDN, os tratamentos N24 e N48 aumentaram a concentração molar de 11 propionato (P < 0,01), a concentração total de AGCC (P < 0,01) e diminuiu a relação acetato:propionato (P < 0,01). Com base nos dados obtidos é possível concluir que os tratamentos N24 e N48 aumentaram o peso final dos cordeiros, e alterou positivamente fermentação ruminal dos ovinos, por outro lado, a narasina mostrou diminuição na sua capacidade como moduladora da fermentação ruminal no intervalo de fornecimento maior que dois dias (72 horas/N72).
The intake on the correct dosage and frequency are the main difficulties of supplying ionophores for animals on high forage diets. Therefore, the aim of this study was to evaluate the frequency of supplementation of narasin over performance (Exp. I), ruminal fermentation parameters, nutrient apparent digestibility and nitrogen balance (Exp. II) on sheep fed high forage diets. The experimental diets consisted on 95% coastcross hay and 5% ground corn used as a delivery vehicle of the additive. The treatments were: Control (C): daily supply of concentrate without the ionophore; narasin 24 hours (N24): daily supply of 13 mg of narasin/kg of DM; narasin 48 hours (N48): supply of narasin every 48 hours (every other day), being provided 26 mg of Narasin/kg of DM on the first day and only the ground corn on the second day (an average of 13 mg of narasin/kg of DM); narasin 72 hours (N72): supply of narasin every 72 hours (one day receiving the additive followed by two days without receiving it), being provided 39 mg of narasin/kg of DM on the first day and only the ground corn on the second and third days. The statistical analysis was done using the MIXED procedure on SAS (2002) and the effects were considered significant when P 0.05. Experiment I: Were used 44 lambs (33.31 ± 0.59 kg) in a randomized block experimental design, the trial lasted 105 days. There was no effect for DMI (P = 0.28), the daily inclusion of narasin (N24) and every 48 hours (N48) increased the ADG (P = 0.03) and the FE (P < 0.01). Experiment II: Were used 4 male lambs (Dorper x Santa Inês, castrated and cannulated in the rumen) in a 4 x 4 Latin square experimental design. The trial lasted 144 days, divided in 4 periods of 36 days each. The first twelve days of each period were used as wash-out, from the 13th to the 36th day the animals received the experimental diets, and the data collection (feces, urine and ruminal fluid) were done on the last six days of each period. . It was not the effect on the digestibility of DM (P = 0.30) and NDF (P = 0.14). The daily inclusion of narasin (N24) and every 48 hours (N48) increased the molar concentration of propionate (P < 0.01), the total concentration of SCFA (P <0.01) and reduced the acetate to propionate (acetate:propionate ratio) ratio (P < 0.01). Based on this data it was possible to 13 conclude that the daily supply of narasin (N24) and every 48 hours (N48) affected the performance and ruminal fermentation parameters on sheep, but this effects decreased when intervals bigger than 48 hours (N72) were used.
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Ali, H. R. H., Howell G. M. Edwards, John Kendrick, and Ian J. Scowen. "Vibrational spectroscopic study of fluticasone propionate." Elsevier, 2009. http://hdl.handle.net/10454/4724.

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Luticasone propionate is a synthetic glucocorticoid with potent anti-inflammatory activity that has been used effectively in the treatment of chronic asthma. The present work reports a vibrational spectroscopic study of fluticasone propionate and gives proposed molecular assignments on the basis of ab initio calculations using BLYP density functional theory with a 6-31G* basis set and vibrational frequencies predicted within the quasi-harmonic approximation. Several spectral features and band intensities are explained. This study generated a library of information that can be employed to aid the process monitoring of fluticasone propionate.
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Polizel, Daniel Montanher. "Utilização de narasina na nutrição de ovinos." Universidade de São Paulo, 2017. http://www.teses.usp.br/teses/disponiveis/10/10135/tde-19012018-095611/.

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Os ionóforos possuem papel importante como manipuladores da fermentação ruminal, principalmente por melhorar a eficiência energética e proteica nos animais ruminantes. A narasina é um ionóforo capaz de fazer controle microbiológio no ambiente ruminal. Entretanto, a literatura possui poucas informações sobre a utilização de narasina na nutrição de ovinos. O presente trabalho teve como objetivos avaliar a utilização de doses de narasina em dietas de ovinos alimentados contendo elevado teor de concentrado ou volumoso. A hipotese é que a narasina tenha a capacidade de alterar os produtos finais da fermentação ruminal, melhorando a utilização dos nutrientes e o metabolismo de nitrogênio de ovinos. No Exp I os tratamentos experimentais foram definidos de acordo com a inclusão ou não de aditivos na dieta contendo elevado teor de concentrado, sendo utilizado uma dieta Controle (C), em que não houve a inclusão de ionóforo; a adição de 25 ppm de monensina sódica (M); 5 ppm (N5); 10 ppm (N10); e 15 ppm de narasina (N15). A inclusão de 5, 10 e 15 mg de narasina/kg de MS aumentou o ganho de peso e a eficiência alimentar de cordeiros alimentados durante 56 dias com dieta contendo 90% de concentrado. No Exp II foram avaliadas as mesmas dietas do exp I. A inclusão de 5, 10 e 15 mg de narasina/kg de MS reduziu o CMS e aumentou o coeficiente de digestibilidade aparente dos nutrientes da MS, MO, PB, gordura e CNF. Além disso, após o período de adaptação houve efeito quadrático para a proporção molar de acetato e a relação acetato:propionato com o aumento das doses de narasina, entretanto, não alterou o pH ruminal. As doses de narasina reduziram linearmente a concentração de amônia no fluido ruminal. A inclusão de narasina nas dietas de borregos tendeu a diminuir o consumo de nitrogênio e reduziu a eliminação de nitrogênio pelas fezes e pela urina. No Exp III os tratamentos foram definidos pela inclusão de doses de narasina em dietas contendo elevado teor de volumoso, sendo o tratamento controle (N0: sem a adição de ionóforo) e a inclusão de 8, 16, 24 e 32 mg de narasina/kg de MS. A inclusão de 0, 8, 16, 24 ou 32 mg de narasina/kg de MS em dietas de borregos alimentados com elevado teor de volumoso não afetou o consumo de matéria seca e tendeu a aumentar linearmente o coeficiente de digestibilidade da FDN. As doses de narasina não alteraram a proporção molar de AGCC, entretanto aumentou a concentração total de AGCC e diminuiu linearmente a concentração de amonia no fluido ruminal. Com base nesses dados foi possivel concluir que a narasina pode ser utilizada em dietas de ovinos aumentando o desempenho dos animais.
Ionophores play an important role as ruminant fermentation manipulators mainly for improving energy and protein efficiency in ruminant. Narasin is an ionophore capable of making microbiological control in the ruminal environment. However, the literature has little information on the use of narasin in sheep nutrition. The objectives of this study were to evaluate the use of doses of narasin in diets of sheep fed diets containing high concentrate or forage contents. The hypothesis is that narasin has the ability to alter the final products of ruminal fermentation, improving nutrient utilization and nitrogen metabolism of sheep. In the Exp I the experimental diets were defined according of the inclusion or not of additives in the diet containing high concentrate, using a control diet (C: no ionophore); the addition of 25 mg of monensin/kg of DM (M); 5 (N5), 10 (N10) or 15 mg of narasin/kg of DM. The inclusion of 5, 10 and 15 mg of narasin / kg of DM increased the average daily gain and feed efficiency of lambs fed for 56 days on a diet containing 90% concentrate. In the Exp II were evaluated the same diets used in the Exp I. The inclusion of 5, 10 and 15 mg narasin / kg DM reduced CMS and increased the apparent digestibility coefficient of DM, OM, CP, fat and NFC. In addition, after the adaptation period there was a quadratic effect for the molar proportion of acetate and the acetate: propionate ratio with increasing doses of narasin, however, did not alter the ruminal pH. The doses of narasin linearly reduced the concentration of ammonia in the ruminal fluid. The inclusion of narasin in diets of wethers tended to reduce nitrogen consumption, and reduced the elimination of nitrogen through feces and urine. In the Exp III the experimental diets were defined by the inclusion of doses of narasin in diets containing high forage contend, being the control diets (N0: no ionophore), and inclusion of 8, 16, 24 or 32 mg of narasin/kg od DM. the inclusion of 0, 8, 16, 24 or 32 mg of narasin / kg of DM in diets of lambs fed with high volume did not affect dry matter intake and tended to linearly increase the NDF digestibility coefficient. Doses of narasin did not alter the molar ratio of AGCC, however increased the total concentration of AGCC in and decreased linearly the concentration of ammonia in the ruminal fluid. Based on these data it was possible to conclude that narasin can be use in sheep diets to improve animal performance
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De, Wet Martie. "The effect of colonic propionate and the acetate : propionate ratio on risk markers for cardiovascular disease in westernised African men." Thesis, Bloemfontein : Central University of Technology, Free State, 2009. http://hdl.handle.net/11462/30.

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Holland, Gail Skene. "Diversity of propionate producing bacteria from the pig gastrointestinal tract." Thesis, University of Aberdeen, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.493590.

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Early weaning and a reduction in the use of antimicrobial growth promoters tend to increase the risk of enteric disease during a period when young pigs are particularly vulnerable, not least due to their immature gastrointestinal and immune systems. Additionally, young animals have yet to acquire a stable, mature commensal microflora. This study examined anaerobic bacterial groups and species present in the different sections of the porcine gastrointestinal tract (GIT), and attempted to identify components of the healthy microflora that might be used to reduce the risk of disease through prophylactic use as probiotics.
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Fauzee, Ayeshah Fateemah Beebee. "Development, manufacture and assessment of Clobetasol 17-propionate cream formulations." Thesis, Rhodes University, 2011. http://hdl.handle.net/10962/d1013324.

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Eczema or dermatitis is the most common dermatological condition accounting for one-third of all diagnoses in the total population surveyed in South Africa. The prevalence of seborrhoeic dermatitis, extreme photodermatitis and severe psoriasis has increased markedly over the last decade and this increase may be ascribed to the HIV epidemic, first diagnosed in South Africa in 1982. Potent innovator corticosteroids, such as clobetasol 17-propionate (CP) that are used to treat skin disorders, are expensive and there is therefore a need for the production of generic topical corticosteroid products. Formulation and manufacturing processes can be challenging aspects for formulation scientists to produce a robust product that will elicit an appropriate and desirable pharmacokinetic-pharmacodynamic profile. Laboratory scale CP creams were manufactured using different concentrations of Gelot® 64 and propylene glycol in order to establish a composition that would produce a formulation, with similar physical and chemical characteristics and in vitro release profile as an innovator product, Dermovate®. These formulations were assessed in terms of their viscosity, spreadability, pH, content uniformity and in vitro release characteristics using a Franz diffusion cell apparatus. A formulation containing 3% w/w Gelot® 64 and 46% v/v propylene glycol (CPLS-02) was found to exhibit similar viscosity and spreadability characteristics and released CP in a manner similar to Dermovate®. The mechanism of drug release was evaluated using mathematical models such as zero order, first order and Higuchi models. In addition, the in vitro release profiles were characterised by use of difference (f1) and similarity (f2 and Sd) factors. A scale-up formulation with the same % w/w composition as the laboratory scale was also investigated following manufacture using a Wintech® cream/ointment mixer. A Central Composite Design approach was used to investigate the effect of process variables on the performance of the scale-up cream formulations. The homogenisation speed, anchor speed, homogenisation time and cooling time were the process variables investigated. Thirty scale-up batches were manufactured and analysed in terms of their viscosity, spreadability, pH, % drug content and cumulative % drug released per unit area over 72 hours. Model fitting using Design-Expert® software was undertaken and revealed that a correlation between the process variables and the cream responses was most suitably described by quadratic polynomial relationships. The homogenisation speed had the most significant effect on the quality of the scale-up formulations, whereas the anchor speed had a secondary effect on the measured responses, for the formulations investigated. The qualitative interpretation and statistical analysis of the in vitro release data from the scale-up formulations using ANOVA and the f1, f2 and Sd factors revealed that one scale-up batch (CPSU-04), for which the process variables were a homogenisation speed of 1900 rpm, an anchor speed of 35 rpm, a homogenisation time of 100 minutes and a cooling time of 100 minutes, released CP at a similar rate and extent to Dermovate®. A diffusion-controlled mechanism appeared to be predominant in these formulations. A human skin blanching study, using both visual and chromameter assessments, was performed to establish whether batch CPSU-04 was bioequivalent to Dermovate®. The bioequivalence of the selected scale-up formulation to Dermovate® was confirmed, following the calculation of a 90% CI.
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Besnier, Sandrine. "Propionate de fluticasone : corticoïde inhalé dans le traitement de l'asthme." Bordeaux 2, 2000. http://www.theses.fr/2000BOR2P021.

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Ohl, Jean. "Hepatotoxicite du propionate d'erythromycine : a propos de trois observations personnelles." Université Louis Pasteur (Strasbourg) (1971-2008), 1986. http://www.theses.fr/1986STR1M147.

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Fontana, Márcia Camponogara. "NANOPARTÍCULAS CONTENDO PROPIONATO DE CLOBETASOL: PREPARAÇÃO, CARACTERIZAÇÃO E INCORPORAÇÃO EM HIDROGÉIS." Universidade Federal de Santa Maria, 2010. http://repositorio.ufsm.br/handle/1/5911.

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The aim of this work was the development of nanostructured formulations containing clobetasol propionate. Initially, it was validated a chromatographic method to assay clobetasol propionate in nanocapsule suspensions. Clobetasol propionate-loaded nanocapsules and nanospheres of poly(ε-caprolactone) (PCL) and nanoemulsion (0.5 mg mL-1) were prepared by the interfacial deposition of preformed polymer method, nanoprecipitation and spontaneous emulsification, respectively. Formulations were characterized by means of drug content, encapsulation efficiency, pH, mean size, polydispersity index, zeta potential, morphology analysis, and stability under storage. The PCL nanocapsules showed the highest physicochemical stability, followed by the nanoemulsions and nanospheres. In the evaluation of in vitro release of clobetasol propionate, the nanocapsules showed a better control of drug release, according to the biexponential model. The photodegradation study of clobetasol propionate against UVA light showed the importance of the polymer and the oil in the nanoparticles to protect the drug from light. From these results, the nanocapsules were chosen for the study of the influence of the polymerid material on the physicochemical stability umder storage, photostability, release profile of the drug and its release mechanism. The nanocapsules prepared with poly(lactide) (PLA) showed a higher stability in comparison to the nanocapsules prepared with poly(lactide-co-glycolide) 50:50 and 85:15, although its stability was lower than nanocapsules prepared with PCL. Photodegradation studies demonstrated the pretection of the nanoencapsulated drug, regardless of the polymeric material of the nanocapsule s wall. The in vitro release study demonstrated the controlled release of the drug according to an anomalous transport. Due to these results, the nanocapsules prepared with PCL were selected for the development and preparation of hydrogels. Similar formulations containing nanospheres and nanoemulsion were used to evaluate the influence of polymer and oil on different properties of the hydrogels. These dosage forms were evaluated for drug content, pH, spreadability, rheology and in vitro drug release. All hydrogels presented properties compatible to the topical application. The presence of the drug-loaded nanoparticles in hydrogels led a slower drug release, especially for the formulation containing nanocapsules. The drug release profile was according to the Higuchi model.
Este trabalho teve como principal objetivo o desenvolvimento de formulações nanoestruturadas contendo propionato de clobetasol. Inicialmente, foi validado um método cromatográfico para análise do propionato de clobetasol em suspensões de nanocápsulas poliméricas. As nanocápsulas e nanoesferas de poli(ε-caprolactona) (PCL) e nanoemulsões contendo propionato de clobetasol (0,5 mg/mL) foram preparadas pelo método da deposição interfacial do polímero pré-formado, nanoprecipitação e emulsificação espontânea, respectivamente. Foram avaliados teores de fármaco, eficiências de incorporação, pHs, diâmetros de partícula, índices de polidispersão, potenciais zeta, características morfológicas e estabilidade frente ao armazenamento das diferentes formulações. As nanocápsulas apresentaram maior estabilidade físico-química, seguida pelas nanoemulsões e nanoesferas. Na avaliação da liberação in vitro do propionato de clobetasol, as nanocápsulas apresentaram o maior controle na liberação do fármaco, seguindo um modelo biexponencial. O estudo da fotodegradação do propionato de clobetasol frente à luz UVA demonstrou a importância da presença do polímero e do óleo para o aumento da fotoestabilidade. Diante destes resultados, as nanocápsulas foram selecionadas para o estudo da influência do material polimérico sobre as características físico-químicas, estabilidade frente ao armazenamento, fotoestabilidade, perfil de liberação do fármaco e seu mecanismo de liberação. As nanocápsulas preparadas com poli(ácido lactídeo) (PLA) apresentaram uma maior estabilidade frente ao armazenamento em comparação com as nanocápsulas preparadas com poli(ácido lactídeo-coglicolídeo) 50:50 e 85:15, embora sua estabilidade tenha sido inferior às nanocápsulas preparadas com PCL. O estudo da fotodegradação demonstrou a proteção do fármaco quando nanoencapsulado, independente do tipo de polímero empregado na sua preparação. A liberação in vitro demonstrou a liberação controlada do fármaco com transporte anômalo. Diante de todos esses resultados, as nanocápsulas preparadas com PCL foram selecionadas para o desenvolvimento de formas farmacêuticas semissólidas (hidrogéis). Formulações similares contendo nanoesferas e a nanoemulsão foram utilizadas para se avaliar a influência do polímero e do óleo sobre diferentes propriedades dos hidrogéis. Estas formas farmacêuticas foram avaliadas quanto ao teor de fármaco, pH, espalhabilidade, reologia e liberação in vitro do fármaco. Os hidrogéis apresentaram propriedades compatíveis com a aplicação tópica. A presença do fármaco nanoencapsulado nos hidrogéis proporcionou sua liberação controlada, principalmente para as formulações contendo as nanocápsulas. O perfil de liberação do fármaco a partir dos hidrogéis seguiu o modelo de Higuchi.
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Tavassoli-Salardini, Fereshteh, of Western Sydney Nepean University, and Faculty of Science and Technology. "Inhibition of mild steel corrosion in aqueous media with sodium propionate." THESIS_FST_XXX_TavassoliSalardini_F.xml, 1996. http://handle.uws.edu.au:8081/1959.7/233.

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The potential use of sodium propionate as a corrosion inhibitor for mild steel in aqueous media is investigated using a range of electrochemical and surface analytical techniques. The use of sodium propionate for the inhibition of mild steel corrosion is discussed, and the effective pH range of sodium propionate using various buffers is investigated. The effectiveness of sodium propionate as an inhibitor for mild steel pitting corrosion in the presence of various concentrations of CI- is studied. The effect of some oxidants, IO3-, BrO3-, NO32- on the anodic behaviour of mild steel in deaerated 0.01M carboxylate solutions of acetate, propionate, formate, succinate and salicylate is investigated. The critical temperature for effective inhibition of mild steel corrosion with sodium propionate is established, and the chemical composition of the film formed on mild steel surface in sodium propionate solution is studied using surface sensitive Fourier transform infrared spectroscopy FTIR. The efficiency of sodium propionate is compared to that of conventional inhibitors and a mechanism for the inhibition of mild steel corrosion with sodium propionate is proposed.
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Books on the topic "Propionate"

1

Spadafora, Peter G. Effects of acetate and propionate on metabolism. Ottawa: National Library of Canada = Bibliothèque nationale du Canada, 1992.

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Trakas, Kostas. A cost-effectiveness assessment of fluticasone propionate, budesonide, and beclomethasone dipropionate for the treatment of moderate to severe asthma. Ottawa: National Library of Canada = Bibliothèque nationale du Canada, 1999.

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Toong, Samuel Y. Modulation of [alpha]-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors by a novel organic nitrate ester. Ottawa: National Library of Canada, 1999.

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Beier, Emmett. Clobetasol Propionate. Independently Published, 2019.

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Misra, Harvey. Clobetasol Propionate. Lulu Press, Inc., 2021.

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Murphy, Ivan. Clobetasol Propionate Treatment. Lulu Press, Inc., 2022.

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Feest, Veda. Fougerad Propionate Cream USP. Independently Published, 2019.

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OLIVIA, Isabella. Advair (fluticasone Propionate and Salmeterol Xinafoate). Independently Published, 2018.

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HOPPE, Joyce. Advair (fluticasone Propionate and Salmeterol Xinafoate). Independently Published, 2018.

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HARRIS, Kayla. Advair (fluticasone Propionate and Salmeterol Xinafoate). Independently Published, 2018.

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Book chapters on the topic "Propionate"

1

Bährle-Rapp, Marina. "Calcium Propionate." In Springer Lexikon Kosmetik und Körperpflege, 82. Berlin, Heidelberg: Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/978-3-540-71095-0_1510.

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Gooch, Jan W. "Cellulose Propionate." In Encyclopedic Dictionary of Polymers, 129. New York, NY: Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-6247-8_2117.

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Bährle-Rapp, Marina. "Magnesium Propionate." In Springer Lexikon Kosmetik und Körperpflege, 336. Berlin, Heidelberg: Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/978-3-540-71095-0_6221.

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Bährle-Rapp, Marina. "Myristyl Propionate." In Springer Lexikon Kosmetik und Körperpflege, 365. Berlin, Heidelberg: Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/978-3-540-71095-0_6786.

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Bährle-Rapp, Marina. "Arachidyl Propionate." In Springer Lexikon Kosmetik und Körperpflege, 44. Berlin, Heidelberg: Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/978-3-540-71095-0_770.

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Gooch, Jan W. "Propyl Propionate." In Encyclopedic Dictionary of Polymers, 593. New York, NY: Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-6247-8_9544.

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Gooch, Jan W. "Ethyl Propionate." In Encyclopedic Dictionary of Polymers, 283. New York, NY: Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-6247-8_4626.

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Gooch, Jan W. "Amyl Propionate." In Encyclopedic Dictionary of Polymers, 38. New York, NY: Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-6247-8_600.

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Gooch, Jan W. "Vinyl Propionate." In Encyclopedic Dictionary of Polymers, 795. New York, NY: Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-6247-8_12572.

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Bährle-Rapp, Marina. "Ammonium Propionate." In Springer Lexikon Kosmetik und Körperpflege, 32. Berlin, Heidelberg: Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/978-3-540-71095-0_560.

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Conference papers on the topic "Propionate"

1

Bomfin, Luana Schoenhalz, Dárcio Kitakawa, Marcelo Saito Nogueira, and Luis Felipe das Chagas e. Silva de Carvalho. "Low Level Laser Therapy as adjuvant treatment for lower lip lesion." In Latin America Optics and Photonics Conference. Washington, D.C.: Optica Publishing Group, 2022. http://dx.doi.org/10.1364/laop.2022.m2b.6.

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Low-level laser therapy (LLLT) is a very valid option for treatment of oral lesions. A patient with painful ulcerated lesion in lower lip was treated with 0.05% clobetasol propionate and 7 sessions of LLLT.
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Setzke, C., O. Broytman, J. Russell, N. Connor, and M. Teodorescu. "Effect of Fluticasone Propionate on Tongue Muscles Properties." In American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX. American Thoracic Society, 2019. http://dx.doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4029.

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Staples, Karl J., Richard T. McKendry, C. Mirella Spalluto, and Tom M. A. Wilkinson. "Fluticasone propionate reduces influenza infection of human macrophages." In Annual Congress 2015. European Respiratory Society, 2015. http://dx.doi.org/10.1183/13993003.congress-2015.oa4750.

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Stempel, David, Stanley Szefler, Soren Pedersen, Robert Zeiger, Herman Mitchell, Andrew Liu, Ibrahim Raphiou, et al. "LATE-BREAKING ABSTRACT: Safety of salmeterol/fluticasone propionate (FSC) compared to fluticasone propionate (FP) in 4-17 yr olds with asthma." In ERS International Congress 2016 abstracts. European Respiratory Society, 2016. http://dx.doi.org/10.1183/13993003.congress-2016.oa4798.

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Erb, David, Andras Koser, Amanda Emmett, and Glenn Crater. "Safety And Efficacy Of Fluticasone Propionate/Salmeterol Hydrofluoroalkane 134a Metered-Dose-Inhaler Vs. Fluticasone Propionate/Salmeterol DISKUS In Subjects With COPD." In American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans. American Thoracic Society, 2010. http://dx.doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a4460.

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Katial, Rohit, David Bernstein, Charlene Prazma, William Lincourt, and David Stempel. "Long-term Treatment With Fluticasone Propionate (FP) And Salmeterol Via DISKUS® (FSC) Improves Asthma Control Versus Fluticasone Propionate (FP) Alone." In American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans. American Thoracic Society, 2010. http://dx.doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a6652.

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Lee, Dani Do Hyang, Priya Radhakrishnan, Claire M. Smith, and Chris O'Callaghan. "Initial interaction of fluticasone propionate with ciliated respiratory epithelium." In ERS International Congress 2016 abstracts. European Respiratory Society, 2016. http://dx.doi.org/10.1183/13993003.congress-2016.pa975.

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Fodor-Csorba, Katalin, T. Paksi, A. Vajda, S. Holly, E. Gacs-Baitz, A. Dobo, and Antal Jakli. "Chemical processes in liquid crystal composite systems containing cholesteryl propionate." In Liquid Crystals, edited by Marzena Tykarska, Roman S. Dabrowski, and Jerzy Zielinski. SPIE, 1998. http://dx.doi.org/10.1117/12.301283.

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Hagan, John, Brian Netzel, Marc Matthews, Nicole Korpi-Steiner, and Ravinder Singh. "Urinary Fluticasone Propionate-17beta-Carboxylic Acid To Assess Asthma Compliance." In American Thoracic Society 2011 International Conference, May 13-18, 2011 • Denver Colorado. American Thoracic Society, 2011. http://dx.doi.org/10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a3787.

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Yang, Xiuli, Kailei Dong, and Xiaojun Tan. "Study on Catalytic Synthesis of Isobutyl Propionate Using Environmentally Friendly Catalys." In 2012 International Conference on Biomedical Engineering and Biotechnology (iCBEB). IEEE, 2012. http://dx.doi.org/10.1109/icbeb.2012.375.

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Reports on the topic "Propionate"

1

Millar, J. M. Proton and deuterium NMR experiments in zero field. [Perdeuterated p-demethoxybenzene, perdeuterated malonic acid, diethyl terephthalate-d4, nonadecane-2,2'-D2, sodium propionate-D2]. Office of Scientific and Technical Information (OSTI), February 1986. http://dx.doi.org/10.2172/6019096.

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Huber, John Tal, Joshuah Miron, Brent Theurer, Israel Bruckental, and Spencer Swingle. Influence of Ruminal Starch Degradability on Performance of High Producing Dairy Cows. United States Department of Agriculture, January 1994. http://dx.doi.org/10.32747/1994.7568748.bard.

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This research project entitled "Influence of Ruminal Starch Degradability on Performance of High Producing Dairy Cows" had the following objectives: a) Determine effects of feeding varying amounts of ruminally degradable starch (RDS) on efficiency of milk and milk protein production; and 2) Investigate digestive and metabolic mechanisms relating to lactation responses to diets varying in ruminal and total starch degradability. Four lactation studies with high producing cows were conducted in which steam-flaked (~ 75% RDS) was compared with dry-rolled sorghum (~ 50% RDS) grain. All studies demonstrated increased efficiency of conversion of feed to milk (FCM/DMI) and milk protein as amount of RDS in the diet increased by feeding steam-flaked sorghum. As RDS in diets increased, either by increased steam-flaked sorghum, grinding of sorghum, or increasing the proportion of wheat to sorghum, so also did ruminal and total tract digestibilities of starch and neutral-detergent soluble (NDS) carbohydrate. Despite other research by these two groups of workers showing increased non-ammonia N (NAN) flowing from the rumen to the duodenum with higher RDS, only one of the present studies showed such an effect. Post-absorptive studies showed that higher dietary RDS resulted in greater urea recycling, more propionate absorption, a tendency for greater output of glucose by the liver, and increased uptake of alpha-amino nitrogen by the mammary gland. These studies have shown that processing sorghum grain through steam-flaking increases RDS and results in greater yields and efficiency of production of milk and milk protein in high producing dairy cows.
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Varga, Gabriella A., Amichai Arieli, Lawrence D. Muller, Haim Tagari, Israel Bruckental, and Yair Aharoni. Effect of Rumen Available Protein, Amimo Acids and Carbohydrates on Microbial Protein Synthesis, Amino Acid Flow and Performance of High Yielding Cows. United States Department of Agriculture, August 1993. http://dx.doi.org/10.32747/1993.7568103.bard.

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The effect of rumen available protein amino acids and carbohydrates on microbial protein synthesis, amino acid flow and performance of high yielding dairy cows was studied. A significant relationship between the effective degradabilities of OM in feedstuffs and the in vivo ruminal OM degradation of diets of dairy cows was found. The in situ method enabled the prediction of ruminal nutrients degradability response to processing of energy and nitragenous supplements. The AA profile of the rumen undegradable protein was modified by the processing method. In a continuous culture study total N and postruminal AA flows, and bacterial efficiency, is maximal at rumen degradable levels of 65% of the CP. Responses to rumen degradable non carbohydrate (NSC) were linear up to at least 27% of DM. Higher CP flow in the abomasum was found for cows fed high ruminally degradable OM and low ruminally degradable CP diet. It appeared that in dairy cows diets, the ratio of rumen degradable OM to rumenally degradable CP should be at least 5:1 in order to maximize postruminal CP flow. The efficiency of microbial CP synthesis was higher for diets supplemented with 33% of rumen undegradable protein, with greater amounts of bacterial AA reaching the abomasum. Increase in ruminal carbohydrate availability by using high moisture corn increased proportions of propionate, postruminal nutrients flow, postruminal starch digestibility, ruminal availability of NSC, uptake of energy substrates by the mammory gland. These modifications resulted with improvement in the utilization of nonessential AA for milk protein synthesis, in higher milk protein yield. Higher postruminal NSC digestibility and higher efficiency of milk protein production were recorded in cows fed extruded corn. Increasing feeding frequency increased flow of N from the rumen to the blood, reduced diurnal variation in ruminal and ammonia, and of plasma urea and improved postruminal NSC and CIP digestibility and total tract digestibilities. Milk and constituent yield increased with more frequent feeding. In a study performed in a commercial dairy herd, changes in energy and nitrogenous substrates level suggested that increasing feeding frequency may improve dietary nitrogen utilization and may shift metabolism toward more glucogenesis. It was concluded that efficiency of milk protein yield in high producing cows might be improved by an optimization of ruminal and post-ruminal supplies of energy and nitrogenous substrates. Such an optimization can be achieved by processing of energy and nitrogenous feedstuffs, and by increasing feeding frequency. In situ data may provide means for elucidation of the optimal processing conditions.
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