Relevant bibliographies by topics / Progression

Academic literature on the topic 'Progression'

Author: Grafiati
Published: 4 June 2021
Last updated: 22 June 2024

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Journal articles on the topic "Progression"

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Arena, Julieta E., Stephen D. Weigand, Jennifer L. Whitwell, Anhar Hassan, Scott D. Eggers, Günter U. Höglinger, Irene Litvan, and Keith A. Josephs. "Progressive supranuclear palsy: progression and survival." Journal of Neurology 263, no. 2 (December 24, 2015): 380–89. http://dx.doi.org/10.1007/s00415-015-7990-2.

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Wilson, Mark. "Measuring progressions: Assessment structures underlying a learning progression." Journal of Research in Science Teaching 46, no. 6 (August 2009): 716–30. http://dx.doi.org/10.1002/tea.20318.

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Hartmann, J. T., F. Heidel, J. Stoehlmacher, M. Duex, J. R. Izbicki, A. Elsaid, E. Wardelmann, T. Fischer, E. Jaeger, and S. Al-Batran. "Pattern of progression and its impact on outcome in patients with gastrointestinal stromal tumors after initial response to imatinib mesylate: A retrospective multicenter long-term follow-up study." Journal of Clinical Oncology 24, no. 18_suppl (June 20, 2006): 9541. http://dx.doi.org/10.1200/jco.2006.24.18_suppl.9541.

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9541 Background: To investigate the clinical impact of the different types of disease progression (focal v extensive) in patients (pts) with metastatic gastrointestinal stromal tumors (GIST) after initial response to imatinib. Methods: Pts who received imatinib for metastatic GIST at three Cancer Centers and who have been followed up for at least 2.5 years were eligible for the study. Disease progression was classified as focal or extensive as defined by protocol. Responses were evaluated according to WHO criteria. Progression-free survival (PFS) and overall survival (OS) were calculated according to the Kaplan-Meier-method. In three pts with focal progressions, serial biopsies were obtained for mutation analysis. Results: Thirty-eight patients (21 men; mean age 58.4 years; range, 37–73 years) were included in the analysis. After a median follow-up of 31.8 mos, 25 of 38 (65.8%) patients had progressed. Nine of 25 progressions were classified as focal and 16 as extensive. Salvage therapies included dose escalation of imatinib with or without surgical resection. Median and 6- and 12-mos PFS were 11.3 mos, 89%, and 40% in pts with focal progression, and 2.5 mos, 39%, and 32%, in patients with extensive progression, respectively. The median OS was 22.8 mos in pts with extensive progression, and was not reached in pts with focal progression. Two subsequent focal progressions in one pt were associated with 2 different secondary KIT-mutations, whereas non-progressive disease harbored the original KIT-mutation alone. Conclusions: Imatinib resistance seems to be partial in a subset of progressing GIST pts. These pts may benefit from local treatment and imatinib continuation and further investigation of imatinib combinations with other compounds appears warranted. Extensive progression is associated with a dismal survival. No significant financial relationships to disclose.
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Plotkin, Daniel, Max Coleman, Derrick Van Every, Jaime Maldonado, Douglas Oberlin, Michael Israetel, Jared Feather, Andrew Alto, Andrew D. Vigotsky, and Brad J. Schoenfeld. "Progressive overload without progressing load? The effects of load or repetition progression on muscular adaptations." PeerJ 10 (September 30, 2022): e14142. http://dx.doi.org/10.7717/peerj.14142.

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Background Progressive overload is a principle of resistance training exercise program design that typically relies on increasing load to increase neuromuscular demand to facilitate further adaptations. However, little attention has been given to another way of increasing demand—increasing the number of repetitions. Objective This study aimed to compare the effects of two resistance training programs: (1) increasing load while keeping repetition range constant vs (2) increasing repetitions while keeping load constant. We aimed to compare the effects of these programs on lower body muscle hypertrophy, muscle strength, and muscle endurance in resistance-trained individuals over an 8-week study period. Methods Forty-three participants with at least 1 year of consistent lower body resistance training experience were randomly assigned to one of two experimental, parallel groups: A group that aimed to increase load while keeping repetitions constant (LOAD: n = 22; 13 men, nine women) or a group that aimed to increase repetitions while keeping load constant (REPS: n = 21; 14 men, seven women). Subjects performed four sets of four lower body exercises (back squat, leg extension, straight-leg calf raise, and seated calf raise) twice per week. We assessed one repetition maximum (1RM) in the Smith machine squat, muscular endurance in the leg extension, countermovement jump height, and muscle thickness along the quadriceps and calf muscles. Between-group effects were estimated using analyses of covariance, adjusted for pre-intervention scores and sex. Results Rectus femoris growth modestly favored REPS (adjusted effect estimate (CI90%), sum of sites: 2.8 mm [−0.5, 5.8]). Alternatively, dynamic strength increases slightly favored LOAD (2.0 kg [−2.4, 7.8]), with differences of questionable practical significance. No other notable between-group differences were found across outcomes (muscle thicknesses, <1 mm; endurance, <1%; countermovement jump, 0.1 cm; body fat, <1%; leg segmental lean mass, 0.1 kg), with narrow CIs for most outcomes. Conclusion Both progressions of repetitions and load appear to be viable strategies for enhancing muscular adaptations over an 8-week training cycle, which provides trainers and trainees with another promising approach to programming resistance training.
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Bhavana S, Junagade, and Sabnis Anjali S. "Schizencephaly: A Neuronal Progression Disorder." Indian Journal of Anatomy 7, no. 2 (2018): 215–17. http://dx.doi.org/10.21088/ija.2320.0022.7218.19.

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Malpetti, Maura, Luca Passamonti, Peter Simon Jones, Duncan Street, Timothy Rittman, Timothy D. Fryer, Young T. Hong, et al. "Neuroinflammation predicts disease progression in progressive supranuclear palsy." Journal of Neurology, Neurosurgery & Psychiatry 92, no. 7 (March 17, 2021): 769–75. http://dx.doi.org/10.1136/jnnp-2020-325549.

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IntroductionIn addition to tau pathology and neuronal loss, neuroinflammation occurs in progressive supranuclear palsy (PSP). However, the prognostic value of the in vivo imaging markers for these processes in PSP remains unclear. We test the primary hypothesis that baseline in vivo imaging assessment of neuroinflammation in subcortical regions predicts clinical progression in patients with PSP.MethodsSeventeen patients with PSP–Richardson’s syndrome underwent a baseline multimodal imaging assessment, including [11C]PK11195 positron emission tomography (PET) to index microglial activation, [18F]AV-1451 PET for tau pathology and structural MRI. Disease severity was measured at baseline and serially up to 4 years with the Progressive Supranuclear Palsy Rating Scale (PSPRS) (average interval of 5 months). Regional grey-matter volumes and PET ligand binding potentials were summarised by three principal component analyses (PCAs). A linear mixed-effects model was applied to the longitudinal PSPRS scores. Single-modality imaging predictors were regressed against the individuals’ estimated rate of progression to identify the prognostic value of baseline imaging markers.ResultsPCA components reflecting neuroinflammation and tau burden in the brainstem and cerebellum correlated with the subsequent annual rate of change in the PSPRS. PCA-derived PET markers of neuroinflammation and tau pathology correlated with regional brain volume in the same regions. However, MRI volumes alone did not predict the rate of clinical progression.ConclusionsMolecular imaging with PET for microglial activation and tau pathology can predict clinical progression in PSP. These data encourage the evaluation of immunomodulatory approaches to disease-modifying therapies in PSP and the potential for PET to stratify patients in early phase clinical trials.
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Bogucki, Andrzej, Justyna Pigońska, Iwona Szadkowska, and Agata Gajos. "Unilateral progressive muscular atrophy with fast symptoms progression." Neurologia i Neurochirurgia Polska 50, no. 1 (January 2016): 52–54. http://dx.doi.org/10.1016/j.pjnns.2015.10.009.

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Gil‐Perotin, Sara, Carmen Alcalá, Francisco Carlos Pérez‐Miralles, and Bonaventura Casanova. "Silent Progression or Bout Onset Progressive Multiple Sclerosis?" Annals of Neurology 86, no. 3 (July 12, 2019): 472. http://dx.doi.org/10.1002/ana.25537.

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Krug, Hollis E., Maren L. Mahowald, Paul B. Halverson, John D. Sallis, and Herman S. Cheung. "Phosphocitrate prevents disease progression in murine progressive ankylosis." Arthritis & Rheumatism 36, no. 11 (November 1993): 1603–11. http://dx.doi.org/10.1002/art.1780361116.

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Whitwell, Jennifer L., Jia Xu, Jay Mandrekar, Jeffrey L. Gunter, Clifford R. Jack, and Keith A. Josephs. "Imaging measures predict progression in progressive supranuclear palsy." Movement Disorders 27, no. 14 (March 13, 2012): 1801–4. http://dx.doi.org/10.1002/mds.24970.

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Dissertations / Theses on the topic "Progression"

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Marchetto, Raquel. "O uso do software GeoGebra no estudo de progressões aritméticas e geométricas, e sua relação com funções afins e exponenciais." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2017. http://hdl.handle.net/10183/172105.

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Esta pesquisa teve por objetivo verificar como é que o aluno consegue por si próprio manipular os recursos, tais como gráficos disponibilizados pelo software GeoGebra, para auxiliar nas práticas diárias de sala de aula, mais especificamente no que tange a construir a conexão entre as progressões aritméticas e as funções afins, bem como entre as progressões geométricas e as funções exponenciais. Este software possibilita fazer análises a partir de diferentes registros tais como: gráficos, tabelas e registros algébricos, seguindo a teoria dos registros semióticos de Duval. Como metodologia, desenvolvemos roteiros de atividades com duas turmas do 2º ano do Ensino Médio do Colégio Estadual Visconde de Bom Retiro. Os alunos foram convidados a construir, verificar e interpretar seus próprios resultados, refletindo e analisando estratégias para responder à questão: Quais relações os alunos conseguem evidenciar, através da comparação entre gráficos (obtidos com o GeoGebra) de funções afins e exponenciais, com progressões aritméticas e geométricas, respectivamente? Ao final da pesquisa, os registros coletados possibilitaram a validação qualitativa da proposta, mostrando que os alunos avançaram na compreensão dos conteúdos abordados.
The aim of this research was to verify how the student can himself manipulate the resources, such as plots made available by the GeoGebra software, to aid in the daily classroom practices, specifically in the construction of the connection between arithmetic progressions and linear functions, as well as between geometric progressions and exponential functions. This software makes possible to analyze from different registers such as: plots, tables and algebraic records, following the theory of semiotic records of Duval. Our methodology consisted in developing activity scripts with students of two classes of the 2nd year of the High School of Visconde de Bom Retiro State College. More specifically, they were asked to build, verify and interpret their own results, speculating and analyzing strategies to answer the question: What relations are the students able to highlight through comparing plots (obtained with GeoGebra) of linear and exponential functions, with arithmetic progressions and geometric, respectively? At the end of the research, the collected records made possible the qualitative validation of the proposal, showing that the students improved their understanding of the focused contents.
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Cergoli, Daniel. "Ensino de logaritmos por meio de investigações matemáticas em sala de aula." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/45/45135/tde-29112017-171710/.

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Neste trabalho são apresentadas duas propostas de sequências didáticas para ensino de logaritmos. A primeira delas é destinada ao aperfeiçoamento de professores de Matemática e a outra, para alunos de Ensino Médio. Tais sequências foram desenvolvidas com base em pesquisas realizadas pelo Prof. João Pedro da Ponte sobre o processo de investigação matemática. A sequência didática para professores foi aplicada no Centro de Aperfeiçoamento do Ensino de Matemática do Instituto de Matemática e Estatística da Universidade de São Paulo (CAEM IME USP). Já a sequência para alunos foi aplicada em uma escola da rede estadual situada no município de São Paulo. Ambas foram analisadas sob os pontos de vista da eficiência e adequação, bem como da clareza das ideias apresentadas. As sequências didáticas têm como ponto de partida a observação das propriedades comuns a várias tabelas, cada uma contendo uma progressão geométrica ao lado de uma progressão aritmética. Tais propriedades caracterizam o que virá a ser definido como logaritmo. Essa introdução ao conceito de logaritmo é diferente da usual, que se baseia na solução de uma equação exponencial. O processo de investigação matemática visa a um aprendizado eficaz por parte do aluno, proporcionado por atividades que conduzam o aluno, de forma gradual, a fazer descobertas, formular conjecturas e buscar validações. Tais investigações são coordenadas e supervisionadas pelo professor, cujo papel é fundamental no processo de construção do conhecimento.
This dissertation presents two didactic sequences for teaching and learning logarithms. One of them aims at Mathematics teachers and is designed for improving their knowledge. The other sequence is meant to be used on high school students. Both didactic sequences were developed based upon research carried out by Professor João Pedro da Ponte on Mathematical Investigations. The didactic sequence for teachers was applied at CAEM IME USP. The one for students was applied at a state school in the city of São Paulo. They were analysed from the points of view of efficiency and of adequacy, as well as of the clarity of the presented ideas. The didactic sequences start with the observation of properties common to multiple tables, each containing a geometric progression side by side with an arithmetic progression. The observed properties characterize what will be later defined as logarithm. Such introduction to the concept of logarithm is different from the usual, which is based on the solution of an exponential equation. The Mathematical Investigation process aims at an effective learning by the students, which is provided by activities that lead the student to gradually make discoveries, formulate conjectures, and search for validations. These investigations are coordinated and supervised by the teacher, whose role in the knowledge construction process is fundamental.
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Biani, Rosana Prado. "A progressão continuada rompeu com mecanismos de exclusão?" [s.n.], 2007. http://repositorio.unicamp.br/jspui/handle/REPOSIP/252086.

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Orientador : Maria Marcia Sigrist Malavasi
Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Educação
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Resumo: Este trabalho analisa a seletividade, o fracasso escolar e a exclusão após a implantação da Progressão Continuada na rede escolar pública estadual de São Paulo. Situa-se na perspectiva do materialismo histórico dialético, sua abordagem é qualitativa e sua metodologia é o estudo de caso. Além do levantamento bibliográfico e do estudo dos documentos oficiais sobre a Progressão Continuada a fim de caracterizá-la enquanto proposta do governo estadual foi feito o acompanhamento, por um ano letivo, em escola da rede estadual de Campinas, em duas classes de 4ª série com o objetivo de observar como se concretizou a proposta na prática escolar cotidiana. Os dados foram obtidos por meio dos documentos escolares dos alunos-sujeitos da pesquisa ¿ fichas de matrícula, listas ¿piloto¿ (com nomes dos alunos, classes às quais pertenciam, listas das classes de recuperação paralela e de férias), espelhos de classe (com notas bimestrais em cada disciplina), das observações do cotidiano escolar ¿ aulas, reuniões de pais, recreios, reforço, sala das professoras e das entrevistas gravadas com os alunos e as professoras. A análise dos dados permite afirmar que: 1) da forma como se concretizou, a Progressão Continuada não rompeu com mecanismos e processos de seleção, fracasso e exclusão levando a escola a manter o seu caráter seletivo e excludente; 2) a exclusão, antes exterior à escola ¿ pelo não ingresso, repetência e evasão ¿ acontece, agora, com a criança na escola ¿ pela pouca qualidade da aprendizagem; 3) os mecanismos de exclusão estão intimamente ligados aos processos avaliativos e intensificaram, dentro da escola, a produção das desigualdades o que, numa análise, contribui com a manutenção das desigualdades sociais. No entanto, pode-se afirmar que a implementação da proposta criou condições objetivas para que as discussões sobre as finalidades da educação, a função social da escola, a organização e a cultura escolar, as práticas pedagógicas e a qualidade na educação ganhassem novas dimensões de análise o que poderá contribuir historicamente para a superação da escola seletiva e a construção da escola para todas as crianças
Abstract: This project analyses the selectivity, the school failure and the exclusion after the implementation of the continued progression in public schools in the state of São Paulo. To be situated on the perspective of historical dialectical materialism, his approach is qualitative and his methodology is the case study. Beyond the bibliographical research and of the analyses of official document about the continued progression in order the label it as a state government proposal, made the follow up for one school year, of two school groups of fourth grades in a public school in the city of Campinas intending to observe how that proposal has been stabilished in the every day school practices. The data was obtained through school documents of the students-subject of this research ¿ such documents were enrollment forms, ¿pilot¿ lists (list containing the names of the students, classes they belong to, reinforcement parallel classes and of vacation), class reports (lists containing students grades on each of subject each bimester), observation of differents moments of the school routine ¿ classes, parent meetings, break, reinforcement, teacher¿s room and finally interviews recorded with students and teachers. The data analyses permit to assert that: 1) the way the Continued Progression proposal was stabilished it didn¿t stop with the mechanisms and process of selection, failure and exclusion in a way that the school kept their selective and excludent character; 2) the exclusion, which in the past was happening outside the school ¿ for the no access, repetition and desertion ¿ now happens with the child in the school ¿ for the little quality of the apprenticeship; 3) the exclusion mechanisms are deeply connected to the evaluation process and intensified, in the school, the production of inequalyties situations which, in analyses, contributes to keeping the social differences and inequalyties. So, we can affirm that the implementation of proposal has criated objectives conditions for wich the discussions about the purpose of education, the social role of the school, the school organization and culture, the pedagogical practices and the quality in education received new dimensions of analyse which may contribute historical for superation of the selective school and the construction of the school for all childrens
Mestrado
Ensino, Avaliação e Formação de Professores
Mestre em Educação
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Josefsson, Erik. "Progression of ancestral brutalism." Thesis, Högskolan i Borås, Institutionen Textilhögskolan, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:hb:diva-17068.

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Within the fine arts, clean and flat structures functionas a narrator for the clean, modern and hightech society. A society with a hygienic fear of death, illness and chaotic structures. The aim of the work is through the materialand surface inflict the hidden, the other side, the darkness and death, in strict and formal mens archetype garments.
Program: Modedesignutbildningen
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Hjeltman, Måsse, and Thomas Ivarsson. "Historieläromedelsböcker, genus & progression." Thesis, Malmö högskola, Lärarutbildningen (LUT), 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-33118.

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I denna undersökning ämnar vi ta reda på hur progressionen ser ut gällande framställningen av kvinnor i historieläromedel från 1960-talet till år 2007. Vi har fokuserat kring dem som oftast marginaliserats i innehållet till fördel för de politiska aktiva så som drottningar och andra politiker. Här är det istället bondhustrur, den hemarbetande kvinnan, sömmerskor, hantverkare och andra yrkesarbetande kvinnor som undersöks för att ta reda på om de har en större plats i dag jämfört med på 1960-talet. Vi vill också ta reda på vilket sätt de framställs och har framställts. Är de aktiva och driver handlingen framåt eller ett bihang till den politiska historien? Vi har sett i vår analys att en positiv förändring skett, men att det finns mycket kvar att göra.
In this study, we intend to find out what the progression looks like when it comes to representations of women in childrens history text books from the 1960´s to year 2007. We have focused on the most frequently marginalized working women for the benefit of the political active women as queens and other politicians.Here it is, instead, peasant wives, the woman home workers, seamstresses, burghers, craftsmen and other working women in these groups who´s being studied and whether they have a larger place today compared to the 1960's. We also want to find out how they are constructed and produced. Are they active and operates forward or a appendage of the political history? We have seen in our analyze that the progression is good, but there’s still much work to do.
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Strouthidis, N. G. "Measuring progression in glaucoma." Thesis, University College London (University of London), 2007. http://discovery.ucl.ac.uk/1446208/.

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Background: Primary open angle glaucoma is characterised by progressive optic neuropathy associated with characteristic visual field loss. The ability to measure disease progression is of vital importance in the management of patients with glaucoma. Conventionally, disease progression has been monitored using static automated perimetry. Recently, devices which image the optic nerve head quantifiably have been introduced. This thesis sets out to compare structural and functional progression in ocular hypertensive subjects followed longitudinally using novel progression algorithms. Plan of research: The investigations may be considered in three parts. Firstly, the factors affecting the test-retest variability of the Heidelberg Retina Tomograph (HRT) are identified and methods to improve repeatability are investigated. Secondly, novel HRT trend and event analyses, based on the findings of the test-retest studies, are compared with established field progression techniques in ocular hypertensive and control subjects. Thirdly, a previously described novel spatial filter is assessed in terms of its impact on the monitoring of visual field progression and in terms of its agreement with a previously described 'structural' map. Results: Rim area was identified as the most repeatable HRT parameter its variability can be improved by using the 320pm reference plane and by using only good quality images. Agreement as regards structural and functional progression was poor, regardless of the estimated specificities of the algorithms used or technique adopted. The novel spatial filter appeared to confer some advantage in terms of specificity, comparable to the effect of confirmatory testing. The functional relationship between test-points, characterised by the filter, correlated well with the expected structural pattern. Clinical significance: The poor agreement suggests that the monitoring of both structure and function is essential to provide the best chance of detecting progression at all stages of the disease. Spatial filtering techniques may provide some additional benefit in the monitoring of progression, particularly once structural data are incorporated.
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Ambring, Erik. "Gameplay Progression : Om skapandet av en jämn progression av spelmoment till dataspelet Testament." Thesis, University of Skövde, School of Humanities and Informatics, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:his:diva-3162.

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Det här arbetets slutgiltiga uppgift har varit att skapa ett första utkast till enövergripande plan för en jämn fördelning av spelmoment för spelet Testament, ett spel som utvecklas för Svenska Kyrkan med syfte att användas inom konfirmandundervisning. Med spelmoment menas exempelvis story, miljö, utrustning och liknande.

Arbetet ger inledningsvis en kort översikt över hur leveldesignen inom dataspel har utvecklats och går därefter in på det mer specifika området gameplay progression, utvecklat av Mike Lopez, som ger en översyn över vad som krävs för att skapa ett spel med en jämn fördelning av spelmoment.Därefter används denna metod för att analysera det redan befintliga spelet The Legend of Zelda: Twilight Princess, för att testa Lopez metod, innan arbetet med att skapa en egen plan tar vid.

Resultatet av uppsatsen har nått målet med en övergripande plan för en jämnfördelning av spelmoment för spelet Testament, en plan som dock kommer att behöva ses över och omarbetas under det att utvecklingen av det faktiska spelet tar vid, men som ger en bra överblick över vilka delar som fungerar väl och vilka som kan behöva extra arbete i den stundande utvecklingen.

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Costa, Antonio Carlos de Lima. "O estudo de Induções e Recorrências - uma abordagem para o Ensino Médio." Universidade Federal da Paraíba, 2015. http://tede.biblioteca.ufpb.br:8080/handle/tede/8064.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPES
This work presents a research on the Induction Principles and the Recurrences, its history, mathematical concepts and applications used. Were developed some statements of Induction Principle and the Recurrences using some basic concepts from Number Theory, Combinatorics, Geometry and Set Theory that can be explored in high school. Was submitted a few activities that can be applied in the classroom of the high school in the development of mathematical concepts such as Arithmetic Progression, Geometric Progression, Geometry, Combinatorial Analysis and Numeric Sets among other topics.
Este trabalho apresenta uma pesquisa sobre os Princípios de indução e Recorrências, sua história, conceitos matemáticos utilizados e aplicações. Foram desenvolvidas algumas demonstrações do Princípio de indução e Recorrências, utilizando-se alguns conceitos básicos de Teoria dos Números, Análise Combinatória, Teoria dos Conjuntos e Geometria que podem ser explorados no Ensino Médio. Foram apresentadas algumas atividades que podem ser aplicadas em sala de aula do Ensino Médio no desenvolvimento de conceitos matemáticos como Progressão Aritmética, Progressão Geométrica, Geometria, Combinação e Conjuntos Numéricos entre outros temas.
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Reichart, Sven. "Progression nach kurativer kolorektaler Karzinomchirurgie." Diss., lmu, 2009. http://nbn-resolving.de/urn:nbn:de:bvb:19-99172.

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Hung, Tzong Tyng Clinical School Prince of Wales Hospital Faculty of Medicine UNSW. "Studies of bladder cancer progression." Awarded by:University of New South Wales, 2009. http://handle.unsw.edu.au/1959.4/39786.

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Bladder cancer (BlCa) is the second most common genitourinary cancer, affecting both men and women. Most (70%) cases present at the superficial stage; 20% of these recur with muscle-invasive disease. Major genetic alterations associated with BlCa include: loss/gain in expression or mutations in Retinoblastoma (RB) gene, human epidermal growth factor receptors (HERs), H-ras, p53 and FGFR3. Only p53 mutations are well correlated with invasive BlCa; other changes show variable correlations with disease status. To understand the progression of BlCa, a model of nine human BlCa cell sublines derived from a single parent but differing in in vivo characteristics, has been developed previously. These cells represent a heterogenous population from a single tumour and a model of different stages of BlCa progression, from non-tumourigenic to invasive. Two sublines were selected for further investigation: C3 (non-tumourigenic) and B8 (invasive). These were transfected with green (C3-GSP-2) and red fluorescent reporters (B8-RSP-gck) respectively to investigate the effects of their co-injection in vivo, specifically, promotion of C3 tumour growth by B8 cells. Surprisingly, B8 tumour growth was inhibited by C3 cells in vivo at different cell numbers and proportions of cells injected. Microarray analysis of C3 and B8 cells revealed differential expression of 1367 genes with dramatic differences in the transforming growth factor-?? and integrin-mediated pathways. Gene expression of BMP2, INHBB, FST, NOG, ID4 and TGF- ??1, in the TGF- ?? pathway was further analysed with qRT-PCR in all nine sublines. Expression of BMP2 was significantly related to tumourigenic potential (p=0.0238, Mann-Whitney) and INHBB to invasive ability (p=0.0476, Mann-Whitney). The BlCa model did not include a metastatic component. To broaden the model, cell lines were established from an invaded lymph-node (B8-RSP-LN) and a bone-metastasis (B8-RSP-BN) after subcutaneous and intra-cardiac injection of B8-RSP-gck cells. No significant differences were observed in the migratory capability and anchorage-independent colony formation of these metastatic cells compared with B8 cells. Evaluation of expression of the panel of TGF-beta genes (BMP2, INHBB, FST, NOG, ID4 and TGF- ??1) and metastasis-related genes (MMP9, MMP2 and KAI1) indicated that expression of BMP2, FST, ID4 and MMP9 was decreased or lost in the metastatic sublines.
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Books on the topic "Progression"

1

Grant, Ernest A. Secondary progressions: Progression of the horoscope. Tempe, Ariz: American Federation of Astrologers, 1988.

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Becker, George Joseph. Academic progression. Carbondale, IL: Becker Family, 1990.

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Hughes, Martin, 1949 May 15-, ed. Progression in learning. Clevedon [England]: Multilingual Matters, 1996.

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Ludlum, Robert. The Aquitaine progression. Toronto: Bantam, 1985.

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Rivera, Geraldo. The Great Progression. New York: Penguin USA, Inc., 2009.

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Scott, Levinson Bruce, ed. The Green progression. New York: Tor, 1992.

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Ludlum, Robert. The Aquitaine progression. Boston, Mass: G.K. Hall, 1985.

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Ludlum, Robert. The Aquitaine progression. Toronto: Bantam, 1985.

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Boonstra, Johannes. G1 phase progression. Georgetown, Tex: Landes Bioscience/Eurekah.com, 2003.

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Ludlum, Robert. The Aquitaine progression. London: Panther, 1985.

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Book chapters on the topic "Progression"

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Zoeller, Margot. "Progression." In Encyclopedia of Cancer, 1–5. Berlin, Heidelberg: Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-642-27841-9_4762-2.

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McCarthy, Daniel, and Ralph Turek. "Progression." In Singing and Dictation for Today#x2019;s Musician, 101–6. New York : Routledge, 2020.: Routledge, 2020. http://dx.doi.org/10.4324/9780367814984-17.

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Zoeller, Margot. "Progression." In Encyclopedia of Cancer, 3716–20. Berlin, Heidelberg: Springer Berlin Heidelberg, 2016. http://dx.doi.org/10.1007/978-3-662-46875-3_4762.

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Nitsch, Barnim. "Progression." In Wörterbuch der Psychotherapie, 532. Vienna: Springer Vienna, 2000. http://dx.doi.org/10.1007/978-3-211-99131-2_1436.

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Hewett, Victoria. "Progression." In Making it as a Teacher, 177–81. Abingdon, Oxon ; New York, NY : Routledge, 2019.: Routledge, 2019. http://dx.doi.org/10.4324/9780429489341-15.

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Zoeller, Margot. "Progression." In Encyclopedia of Cancer, 2998–3001. Berlin, Heidelberg: Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-16483-5_4762.

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Pfingsten, Andreas. "Tax Progression." In The Measurement of Tax Progression, 6–9. Berlin, Heidelberg: Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-82652-8_3.

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McComas, William F. "Learning Progression." In The Language of Science Education, 61. Rotterdam: SensePublishers, 2014. http://dx.doi.org/10.1007/978-94-6209-497-0_53.

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Williams, Susan. "Disease Progression." In Digital Mammography, 99–104. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-10898-3_9.

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Motley, Gary. "Chord Progression." In Harmonic Development and Contrapuntal Techniques for the Jazz Pianist, 132–56. New York: Routledge, 2023. http://dx.doi.org/10.4324/9781003352020-8.

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Conference papers on the topic "Progression"

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Vu, Trung-Kien, Teeradaj Racharak, Satoshi Tojo, Nguyen Thanh, and Nguyen Minh. "Progressive Training in Recurrent Neural Networks for Chord Progression Modeling." In 12th International Conference on Agents and Artificial Intelligence. SCITEPRESS - Science and Technology Publications, 2020. http://dx.doi.org/10.5220/0008951500890098.

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Anderson, Prue. "Bringing learning progressions down to 2-year-olds in reading and mathematics." In Research Conference 2023: Becoming lifelong learners. Australian Council for Educational Research, 2023. http://dx.doi.org/10.37517/978-1-74286-715-1-10.

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ACER’s learning progressions in reading and mathematics describe growth that is mainly focused on skills students demonstrate at and beyond school. These progressions have recently been extended down to describe earlier levels of growth so we now have seamless progressions from skills and understandings toddlers might demonstrate up to highly sophisticated skills and concepts. This presentation briefly outlines ACER’s work and identifies key implications for educators. The pathways that support early reading development were described in progressions for listening comprehension and sounds and letters. Along with an early mathematics progression, these were conceptualised as embedded in an oral language progression. Educators need to understand what early growth in reading and mathematics looks like in order to foster key skills and concepts at an appropriate level for the child. This ensures a strong foundation for children to make good ongoing progress.
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Chrisholm, Chris. "Progression in-between." In ACM SIGGRAPH 98 Electronic art and animation catalog. New York, New York, USA: ACM Press, 1998. http://dx.doi.org/10.1145/281388.281976.

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Lupini, Christopher A. "Multiplex Bus Progression." In SAE 2001 World Congress. 400 Commonwealth Drive, Warrendale, PA, United States: SAE International, 2001. http://dx.doi.org/10.4271/2001-01-0060.

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Oh, A., S. Ash, D. A. Lynch, and S. M. Humphries. "Progression in Deep Learning Emphysema Grade Predicts Disease Progression and Mortality." In American Thoracic Society 2022 International Conference, May 13-18, 2022 - San Francisco, CA. American Thoracic Society, 2022. http://dx.doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a5024.

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Timmins, Lucas H., David S. Molony, Parham Eshtehardi, Michael C. McDaniel, John N. Oshinski, Habib Samady, and Don P. Giddens. "Development of Framework to Examine the Focal Association Between Wall Shear Stress and Coronary Artery Disease Progression in the Clinical Setting." In ASME 2013 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/sbc2013-14476.

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Natural history data on clinical coronary artery disease (CAD) indicates that there is a critical need to prospectively identify rapidly progressing and vulnerable coronary lesions that may cause potentially fatal acute coronary events [1]. Recent prospective clinical investigations have evaluated the value of wall shear stress (WSS) as a prognostic marker for identifying rapidly progressing coronary lesions [2,3]. Data indicate that low WSS is associated with significant plaque progression, while regions of high WSS are associated with plaque regression and phenotypic transformation towards a more vulnerable lesion. While these studies provided unprecedented data on the role of hemodynamic-induced mechanical forces in lesion dynamics, they were limited by a lack of focal understanding of the association between WSS and plaque progression. Specifically, despite the understanding that WSS and plaque progression are heterogeneous around the artery’s circumference, in each image slice WSS values were spatially averaged around the circumference and correlated with average values for changes in virtual histology-intravascular ultrasound (VH-IVUS) defined plaque constituent areas.
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Roberts, Michael D., Ian A. Sigal, Yi Liang, Claude F. Burgoyne, and J. Crawford Downs. "Finite Element Modeling of the Connective Tissues of the Optic Nerve Head in Bilaterally Normal Monkeys." In ASME 2009 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2009. http://dx.doi.org/10.1115/sbc2009-206522.

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Glaucoma is a chronic and progressive optic neuropathy that gradually narrows the field of vision and can culminate in blindness. Despite extensive and prolonged research efforts, the mechanisms that initiate and fuel progression of the disease are not well understood. However, reduction of intraocular pressure (IOP) has been shown to be an effective therapy for slowing glaucomatous progression, although the specific role of IOP in the disease is not well understood.
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Comes, A., G. Sgalla, D. Verdirosi, T. Magrì, J. Simonetti, B. Iovene, F. Varone, and L. Richeldi. "Association of Criteria Defining Progressive Pulmonary Fibrosis With Mortality and Disease Progression." In American Thoracic Society 2024 International Conference, May 17-22, 2024 - San Diego, CA. American Thoracic Society, 2024. http://dx.doi.org/10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a2846.

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Kemelmacher-Shlizerman, Ira, Supasorn Suwajanakorn, and Steven M. Seitz. "Illumination-Aware Age Progression." In 2014 IEEE Conference on Computer Vision and Pattern Recognition (CVPR). IEEE, 2014. http://dx.doi.org/10.1109/cvpr.2014.426.

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Lupini, Christopher A. "Multiplex Bus Progression 2003." In SAE 2003 World Congress & Exhibition. 400 Commonwealth Drive, Warrendale, PA, United States: SAE International, 2003. http://dx.doi.org/10.4271/2003-01-0111.

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Reports on the topic "Progression"

1

Lawing, Chase, Scott Palmtag, and Mehdi Asgari. BWR Progression Problems. Office of Scientific and Technical Information (OSTI), February 2021. http://dx.doi.org/10.2172/1838995.

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St. Germain, Shawn, and Douglas Akers. Accident progression analysis P-300. Office of Scientific and Technical Information (OSTI), April 2016. http://dx.doi.org/10.2172/1467668.

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Li, Hangwen. SPANXB2 and Prostate Cancer Progression. Fort Belvoir, VA: Defense Technical Information Center, December 2014. http://dx.doi.org/10.21236/ada612613.

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Li, Hangwen. SPANXB2 and Prostate Cancer Progression. Fort Belvoir, VA: Defense Technical Information Center, October 2013. http://dx.doi.org/10.21236/ada601287.

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Galaktionov, Konstantin. MicroRNA and Breast Cancer Progression. Fort Belvoir, VA: Defense Technical Information Center, August 2007. http://dx.doi.org/10.21236/ada480199.

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Lin, Chen-Yong. Matriptase Activation in Breast Cancer Progression. Fort Belvoir, VA: Defense Technical Information Center, June 2005. http://dx.doi.org/10.21236/ada439289.

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Holt, Shawn E., and Lynne W. Elmore. Molecular Mechanisms of Prostate Cancer Progression. Fort Belvoir, VA: Defense Technical Information Center, January 2005. http://dx.doi.org/10.21236/ada442183.

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Keller, Evan T. Interleukin-6 and Prostate Cancer Progression. Fort Belvoir, VA: Defense Technical Information Center, July 2001. http://dx.doi.org/10.21236/ada398242.

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Lala, Peeyush K. Nitric Oxide in Mammary Tumor Progression. Fort Belvoir, VA: Defense Technical Information Center, July 2001. http://dx.doi.org/10.21236/ada398946.

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Keller, Evan T. Interleukin-6 and Prostate Cancer Progression. Fort Belvoir, VA: Defense Technical Information Center, July 2002. http://dx.doi.org/10.21236/ada407280.

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