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1

Braak, Heiko, and Kelly Del Tredici. "From the Entorhinal Region via the Prosubiculum to the Dentate Fascia: Alzheimer Disease-Related Neurofibrillary Changes in the Temporal Allocortex." Journal of Neuropathology & Experimental Neurology 79, no. 2 (January 8, 2020): 163–75. http://dx.doi.org/10.1093/jnen/nlz123.

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Abstract The pathological process underlying Alzheimer disease (AD) unfolds predominantly in the cerebral cortex with the gradual appearance and regional progression of abnormal tau. Intraneuronal tau pathology progresses from the temporal transentorhinal and entorhinal regions into neocortical fields/areas of the temporal allocortex. Here, based on 95 cases staged for AD-related neurofibrillary changes, we propose an ordered progression of abnormal tau in the temporal allocortex. Initially, abnormal tau was limited to distal dendritic segments followed by tau in cell bodies of projection neurons of the transentorhinal/entorhinal layer pre-α. Next, abnormal distal dendrites accumulated in the prosubiculum and extended into the CA1 stratum oriens and lacunosum. Subsequently, altered dendrites developed in the CA2/CA3 stratum oriens and stratum lacunosum-moleculare, combined with tau-positive thorny excrescences of CA3/CA4 mossy cells. Finally, granule cells of the dentate fascia became involved. Such a progression might recapitulate a sequence of transsynaptic spreading of abnormal tau from 1 projection neuron to the next: From pre-α cells to distal dendrites in the prosubiculum and CA1; then, from CA1 or prosubicular pyramids to CA2 principal cells and CA3/CA4 mossy cells; finally, from CA4 mossy cells to dentate granule cells. The lesions are additive: Those from the previous steps persist.
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HIRAI, Shunsuke, and Yoshihiro TERAMURA. "3211 Modeling approach for the design process with 3D CAD." Proceedings of Design & Systems Conference 2007.17 (2007): 319–22. http://dx.doi.org/10.1299/jsmedsd.2007.17.319.

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3

ISHIGURO, Eiki, Tohru ISHIDA, Masahiko KITA, Keiichi NAKAMOTO, and Yoshimi TAKEUCHI. "A11 Development of CAD/CAM System for Cross Section's Changing Hole Electrical Discharge Machining : Formulation of Post Processor(Digital design and digital manufacturing (CAD/CAM))." Proceedings of International Conference on Leading Edge Manufacturing in 21st century : LEM21 2009.5 (2009): 251–56. http://dx.doi.org/10.1299/jsmelem.2009.5.251.

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4

Ge, Zheng Hao, Wei Huang, Wei Hua Liu, and Zhi Heng Zhai. "CAD/CAM/CAE for the Parallel Indexing Cam Mechanisms." Applied Mechanics and Materials 44-47 (December 2010): 475–79. http://dx.doi.org/10.4028/www.scientific.net/amm.44-47.475.

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This paper takes the parallel indexing cam mechanism as research object and analyzes the formation of the profile of cam. On the basis of Visual C++6.0 object-oriented method, we have successfully developed the CAD/CAE/CAM system of parallel indexing cam mechanisms, which provides the parameter input dialogue frame with friendly interface. We can generate accurate profile data by using it, then create the three-dimensional model of the parallel indexing cam and assemble it with other parts under the Pro/E environment. At last, we don’t build virtual prototype until we transform the model into ADAMS through special interface Mechanism/Pro. Finally, this paper has researched the theory of contact and collision, carries out the motion simulation. We have received many valuable conclusions of practical application through all of the process.
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Dziubek, Tomasz, and Mateusz Pelc. "Application of CAD/CAE/RP in the modeling process and manufacture of a functional model of a turbocharger." Mechanik, no. 12 (December 2015): 973/062–973/069. http://dx.doi.org/10.17814/mechanik.2015.12.558.

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6

SATO, RYUZO. "CAD-CAM for Apparel Production Process." Sen'i Gakkaishi 41, no. 1 (1985): P32—P38. http://dx.doi.org/10.2115/fiber.41.p32.

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7

Kubota, Yoshihisa, John A. Putkey, Harel Z. Shouval, and M. Neal Waxham. "IQ-Motif Proteins Influence Intracellular Free Ca2+ in Hippocampal Neurons Through Their Interactions With Calmodulin." Journal of Neurophysiology 99, no. 1 (January 2008): 264–76. http://dx.doi.org/10.1152/jn.00876.2007.

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Calmodulin (CaM) is most recognized for its role in activating Ca2+–CaM-dependent enzymes following increased intracellular Ca2+. However, CaM's high intracellular concentration indicates CaM has the potential to play a significant role as a Ca2+ buffer. Neurogranin (Ng) is a small neuronal IQ-motif–containing protein that accelerates Ca2+ dissociation from CaM. In cells that contain high concentrations of both Ng and CaM, like CA1 pyramidal neurons, we hypothesize that the accelerated Ca2+ dissociation from CaM by Ng decreases the buffering capacity of CaM and thereby shapes the transient dynamics of intracellular free Ca2+. We examined this hypothesis using a mathematical model constructed on the known biochemistry of Ng and confirmed the simulation results with Ca2+ imaging data in the literature. In a single-compartment model that contains no Ca2+ extrusion mechanism, Ng increased the steady-state free Ca2+. However, in the presence of a Ca2+ extrusion mechanism, Ng accelerated the decay rate of free Ca2+ through its ability to increase the Ca2+ dissociation from CaM, which in turn becomes subject to Ca2+ extrusion. Interestingly, PEP-19, another neuronal IQ-motif protein that accelerates both Ca2+ association and dissociation from CaM, appears to have the opposite impact than that of Ng on free Ca2+. As such, Ng may regulate, in addition to the Ca2+–CaM-dependent process, Ca2+-sensitive enzymes by influencing the buffering capacity of CaM and subsequently free Ca2+ levels. We examined the relative impact of these Ng-induced effects in the induction of synaptic plasticity.
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8

Katoh, Hiroshi. "Simulation Advancement in Automotive Development: A Brief Review." Applied Mechanics and Materials 761 (May 2015): 22–26. http://dx.doi.org/10.4028/www.scientific.net/amm.761.22.

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The automotive development process is advancing through the utilization of CAD/CAM/CAE. This advancement is being enhanced by proper utilization of CAD/CAM integration, Digital prototyping and Digital mock-up. Until recently, CAD has played the leading role for the digitalization of automotive development. However, recent trend shows that, the leading role is shifted from CAD to analysis simulation. Three-dimensional design, which utilizes digital mock-up, is becoming the main tool for product design. Here, the functional capability and predictive assessment by CAE is the core technology. In addition, this supporting role is helping to realize the concurrent engineering in production engineering field.
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9

Kuang, Wei Hua, and Li Si Chen. "Virtual Product Development and Reliability Design of Camera Cover." Key Engineering Materials 460-461 (January 2011): 40–43. http://dx.doi.org/10.4028/www.scientific.net/kem.460-461.40.

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The paper finished the design of injection molding by UG MoldWizard module, and realized numerical simulation and analysis of injection process by MoldFlow software. Best gate location was obtained. Fill time was deeply studied. Though the mold designing process, it completed the CAD/CAM/CAE integration of the injection molding, and achieved the optimal design of the mold. NC machining of the mold core was programmed by UG NX software. CAD/CAM/CAE greatly improved the development efficient of the mold.
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10

Zaborski, Andrzej. "Manufacturing preparation using CAD and CAD/CAM software." Mechanik 91, no. 7 (July 9, 2018): 567–69. http://dx.doi.org/10.17814/mechanik.2018.7.86.

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A possibility of using contemporary CAD and CAD/CAM systems for computer-integrated developing the processes of preparation products manufacturing is presented. On the example of the modernization of the lock lever of the head of the sewing machine in article discussed design process and production preparation using numerically controlled machines.
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11

Prabhu, N., M. Dev Anand, and V. Sundar. "Integrated CAD/CAE/CAM System for Scorbot-ER Vu Plus Industrial Robot Manipulator." Applied Mechanics and Materials 389 (August 2013): 747–53. http://dx.doi.org/10.4028/www.scientific.net/amm.389.747.

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Robots are required to operate in different environmental conditions facing varieties of end-effector to perform the workspace interactions. This paper deals with integrated CAD/CAE/CAM system for SCORBOT-ER Vu plus Industrial robot manipulator. The DH (DenavitHartenberg) coordinate transformation method was used to perform the robot position analysis. The robot manipulator parametric solid models were constructed using Pro/ENGINEER (Pro/E). Pro/Mechanica was used to simulate the dynamic simulation and working space, CATIA was used to implement the cutting simulation, and the prototype was manufactured using a CNC milling machine. Finally, a CAD/CAE/CAM integrated system for a robot manipulator was developed. This integrated system not only promotes automation capabilities for robot manipulator production, but also simplifies the CAD/CAE/CAM process for a robot manipulator.
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12

Jin, Zhi Gang, Wu Ji Jiang, and Min Xia Yu. "Design and Manufacturing of Air Conditioner Panel Hot Runner Injection Mold Based on CAD/CAE/CAM." Applied Mechanics and Materials 42 (November 2010): 68–72. http://dx.doi.org/10.4028/www.scientific.net/amm.42.68.

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Take air conditioner panel for example, it is introduced that the whole process of hot runner injection mold design and manufacture based on CAD/CAE/CAM technology. The panel structure and injection process were analyzed using HuaSu CAE software, then the panel structure was designed using UG/Mold Wizard software, the NC programming and manufacture simulating of the formed parts were done by UG/MACHINE module at last. Compared with the traditional mold design method, CAD/CAE/CAM technology not only can improve the efficiency, shorten production period, but also can reduce the cost of mold design and manufacture greatly.
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Kacalak, Wojciech, Zbigniew Budniak, and Filip Szafraniec. "Analysis of shaping of the screw surface in the process a of grinding by the grinding wheels using CAD/CAE." Mechanik, no. 10 (October 2016): 1368–69. http://dx.doi.org/10.17814/mechanik.2016.10.365.

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14

Ji, Ai Min, Kun Zhu, Ji Cheng Huang, and Yi Pei Dong. "CAD/CAE Integration System of Mechanical Parts." Advanced Materials Research 338 (September 2011): 272–76. http://dx.doi.org/10.4028/www.scientific.net/amr.338.272.

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The key technologies of CAD/CAM integration of mechanical parts which include parametric modeling technology, model transformation of CAD/CAE and finite element modeling were studied. Based on redevelopment of UG, the process of parametric modeling about typical part was achieved. The identification, selection, extraction, and removal of the details in the CAD model were analyzed. The extraction approach of the mid-surface in the dimensional reduction of the CAD model was executed. The CAD/CAE integration system of the design and finite element analysis for mechanical parts was established by the redevelopment of UG and ANSYS with Visual C++, UG/Open and APDL as tools. The parametric design and automatic finite element analysis for mechanical parts were implemented.
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15

Silva, Nelson R. F. A., Lukasz Witek, Paulo G. Coelho, Van P. Thompson, Elizabeth D. Rekow, and Jim Smay. "Additive CAD/CAM Process for Dental Prostheses." Journal of Prosthodontics 20, no. 2 (February 2011): 93–96. http://dx.doi.org/10.1111/j.1532-849x.2010.00623.x.

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16

Manoharan, Thivakar, Marcin Humpa, Alexander Martha, and Peter Koehler. "Knowledge integration in CAD-CAM process chain." Computer-Aided Design and Applications 13, no. 5 (February 22, 2016): 729–36. http://dx.doi.org/10.1080/16864360.2016.1150720.

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17

Bulavin, V. F., T. G. Bulavina, D. V. Koshutin, and I. S. Petryashov. "CAO / CAE-Engineering Support for the Production of Small Enterprises." Proceedings of Higher Educational Institutions. Маchine Building, no. 8 (749) (August 2022): 47–54. http://dx.doi.org/10.18698/0536-1044-2022-8-47-54.

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The creation of high-tech and science based productions allows designing products with high consumer qualities and manufacturing globally competitive products. New trends associated with the digitalization of design and technological projects are accelerating the integration of material and virtual production. A dynamic environment requires the flexibility of management in the face of accelerated adaptation of manufacture. Such challenges involve long-term forecasting and making quick decisions while maintaining the competitiveness of goods and services over time. The technological transformation of small and medium-sized enterprises as part of the transition to digital production determines their integration into the space of distributed factories. Innovative changes in manufacturing technology are accompanied by the introduction of efficient business processes at all levels. The article considers the formation of a group of competencies ensuring the integration of CAD / CAE / CAO into a single information data flow, as well as their distribution in the field of small and medium-sized machine-building enterprises. A single system of intelligent business process model provides support for parallel work of developers.
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18

Wang, Feng Jun. "Point-Based CAD/CAM Geometric Model Design." Advanced Materials Research 690-693 (May 2013): 2757–61. http://dx.doi.org/10.4028/www.scientific.net/amr.690-693.2757.

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At present, CAD/CAM technology is applied in many areas, and machinery manufacturing was one of these areas in which CAD/CAM technology is the first and most widely used. With the development of CAD/CAM technology, CAD/CAM technology has become a key technology to improve the design and manufacturing standards, and enhance the competitiveness of the industry. In this paper, the concept of point-based geometric models used in CAD/CAM is proposed, the definition of the point-based geometric model and its CAD/CAM application process are suggested, and the geometric characteristics of the point-based geometric model and the CAD/CAM system development methodology are analysed.
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19

OKUDA, Yoko, Keiichi SHIRASE, Kouhei FUKADA, Keiichi NAKAMOTO, and Eiji ARAI. "306 Development of Computer-aided Flexible Process Planning System." Proceedings of The Manufacturing & Machine Tool Conference 2006.6 (2006): 43–44. http://dx.doi.org/10.1299/jsmemmt.2006.6.43.

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20

Yang, D. Y., D. G. Ahn, C. H. Lee, C. H. Park, and T. J. Kim. "Integration of CAD/CAM/CAE/RP for the development of metal forming process." Journal of Materials Processing Technology 125-126 (September 2002): 26–34. http://dx.doi.org/10.1016/s0924-0136(02)00414-4.

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21

Thomas, Kurian K., and Gary W. Fischer. "Integrating CAD/CAM software for process planning applications." Journal of Materials Processing Technology 61, no. 1-2 (August 1996): 87–92. http://dx.doi.org/10.1016/0924-0136(96)02470-3.

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22

KOUNO, Tomoyuki, Tomo KOYAMA, Tatsuhiko SAKAGUCHI, Keiichi NAKAMOTO, and Keiichi SHIRASE. "307 Research on Voxel Model Applying for Machining Process Simulation." Proceedings of The Manufacturing & Machine Tool Conference 2006.6 (2006): 45–46. http://dx.doi.org/10.1299/jsmemmt.2006.6.45.

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23

Qiao, Li Hong, and Jin Zhang. "Integrated Process Planning Based on 3D Product Models." Key Engineering Materials 407-408 (February 2009): 298–302. http://dx.doi.org/10.4028/www.scientific.net/kem.407-408.298.

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One of the major barriers to the integration of CAD, CAPP and CAM is insufficiency and incompatibility of product model data among various application systems. This paper presented an effective approach to achieve integrated process planning with CAD and CAM under a product data management environment based on 3D product models. The system architecture and the processes of an integrated process planning system (3D-IPP) were constructed using feature information and specific CAD/CAPP/CAM integration technologies based on feature. A feature-based product information model is designed as the information source for the 3D-IPP. A feature-based integrated process planning method was developed based on group technology, intelligent decision-making algorithms and parametric operation templates in numerically controlled (NC) programming. The procedures of intelligent process route planning and parametric NC operation planning were addressed. The 3D-IPP system and its implementation provide an effective solution to strive for complete information sharing among application systems of CAD, CAPP and CAM.
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Yan, Zheng Feng, and Zheng Feng Jiang. "Research on the Integrated Design of Dual Mass Flywheel CAD/CAE/CAM." Key Engineering Materials 407-408 (February 2009): 169–73. http://dx.doi.org/10.4028/www.scientific.net/kem.407-408.169.

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Combining the research and development of dual mass flywheel, the paper explores the realizing methods of CAD/CAE/CAM integrated design system. The system is composed of modules including digital structure design and simulation, entire-car NVH analysis, analysis and optimization of formation process and welding process. Based on PDM technique, data sharing and integration could be realized through corresponding interface procedures by establishing a uniform product data model. The paper studies on the digital structure design and simulation, torsional vibration analysis, sheet material forming technology simulation and welding technology simulation. Finally the paper shows the comparison between one type of dual mass flywheel sample test curve and simulation curve.
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Carr, Bruce A., Thomas M. Houlihan, and Michael A. Polini. "CAD/CAM in Phased Maintenance." Journal of Ship Production 7, no. 04 (November 1, 1991): 234–47. http://dx.doi.org/10.5957/jsp.1991.7.4.234.

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The authors' company is a medium-sized engineering company specializing in naval ship repair. The bulk of corporate work centers on the Phased Maintenance (PM) of three classes of ships. Typically, each PM contract covers three to five different ships per class scheduled for 90-day Availabilities at approximately one-year intervals over a period of five years. The type of work to be performed during each Phased Maintenance Availability (PMA) falls into one of two categories: ship alterations or ship repairs. The first group, ship alterations, is characterized by detailed, long-lead engineering and planning efforts, typically beginning 540 days prior to the vessels's arrival. The second group, ship repairs, makes up the other end of the spectrum with short lead times and compressed service details. The majority of repair items are identified 60 days prior to an Availability, while some are not determined until after the vessel has arrived in the shipyard. The engineering department that services PMA work is composed of three disciplines: structural, mechanical and electrical. The mechanical discipline is further subdivided into the areas of machinery and piping/HVAC. While the nature of PMA work within each discipline is peculiar to the application, the process is similar in each. Reference information is gathered and verified, technical analysis is provided where necessary, and detailed drawings are prepared and submitted for Navy approval prior to shipyard production. All drawings are developed using two-dimensional drafting techniques at various sites by teams of computer-aided design (CAD) input operators utilizing color graphic workstations on a multi-shift basis as required by the workload. Completed drawings are transferred to the engineering site over a network link, where additional workstations are available for engineers to check and correct them as necessary
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26

He, Long. "Free Form Shape of Machine Parts Design Based on Microcomputer CAD/CAM System." Applied Mechanics and Materials 556-562 (May 2014): 1346–49. http://dx.doi.org/10.4028/www.scientific.net/amm.556-562.1346.

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CAD/CAM system is one of the most widely used software in the field of mechanical design and manufacturing. The design of the mechanical parts generally uses CAD/CAM software, such as SolidWorks, Unigraphic, Pro/Engineer etc.. In this paper, by using UG software as a development platform, we use the software of UG/OPEN GRIP and UG MACRO as secondary development tool to realize the customization and development of general model of CAD/CAM system, and apply it in the design of professional free format machine parts. In the CAD/CAM system we put free format into parts manufacturing process and technology, and put forward the simple and effective process flow, so as to realize the optimization of CAD/CAM system. It provides the technical reference for the design and process of mechanical components.
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27

Camargo, Isabella Figueiredo, Ludmila Priscilla Manetti, Marilia Zeczkowski, Daniel Sundfeld Neto, Nubia Inocencya Pavesi Pini, Aline Akemi Mori, Brunna Mota Ferrairo, and Fernanda Ferruzzi Lima. "SISTEMAS CAD/CAM E SUAS APLICAÇÕES NA ODONTOLOGIA: REVISÃO DA LITERATURA." Revista Uningá 55, S3 (December 20, 2018): 221–28. http://dx.doi.org/10.46311/2318-0579.55.euj240.

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A tecnologia CAD/CAM é utilizada na odontologia principalmente na produção de estruturas protéticas. Restaurações indiretas são planejadas e fabricadas com o auxílio do computador diminuindo a influência do processo manual executado pelo técnico em prótese dentária (TPD). Além do uso de materiais padronizados, de qualidade industrial, os sistemas CAD/CAM podem ser uma ferramenta útil no diagnóstico e planejamento do tratamento, além de permitir a fabricação e restaurações de ótima qualidade em menor tempo. As restaurações CAD/CAM apresentam desempenho clínico compatível com as restaurações convencionais e esta tecnologia pode ser incorporada na pratica clínico com poucas mudanças. Este estudo mostrará o funcionamento e as aplicações da tecnologia CAD/CAM em odontologia através de uma revisão de literatura, além dos materiais que podem ser utilizados. Esta tecnologia apresenta uma gama enorme de possibilidades e traz inúmeros benefícios tanto para o cirurgião dentista quanto para o TPD. Porém, é preciso conhecer as ferramentas de cada sistema para se beneficiar de suas facilidades, pois, aliar a manufatura computadorizada a técnicas manuais podem garantir melhor acabamento e estética.
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FUKUTA, Yuka, and Toshiyasu KINARI. "Development of CAD / CAM System for Traditional Craft "Drawing / Pattern Carving Shibori" Process." Journal of Textile Engineering 61, no. 6 (2015): 75–83. http://dx.doi.org/10.4188/jte.61.75.

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29

Li, Xueyi, Shuhui Ding, Junying Wei, and Quanwei Wang. "Research on Teaching Method of Mold Course Based on CAD/CAE/CAM Technology." International Journal of Emerging Technologies in Learning (iJET) 12, no. 07 (July 12, 2017): 136. http://dx.doi.org/10.3991/ijet.v12i07.7224.

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The teaching of the traditional mold courses focus on the illustration of theoretical knowledge. Therefore, associating the design, evaluation, and manufacture links as a whole is difficult. Students cannot shape system knowledge, thereby making the study difficult. In addition, traditional teaching cannot meet the current enterprise needs of talents who have mold CAD/CAE/CAM technology. This study presents a teaching method that applies CAD/CAE/CAM technology to mold teaching. First, the positive effects of these technologies on the mold design and manufacturing process are introduced. Thereafter, lamp cover is used as an example to establish a series of computer-aided teaching development processes using existing software for mold design, mold flow analysis, and machining simulation. Lastly, survey results demonstrate that the effects of the proposed teaching method are better than the traditional method. Moreover, students and enterprises are substantially recognized in this teaching method.
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Fernandes, Fábio A. O., Nilo Fuchter Júnior, Anderson Daleffe, Daniel Fritzen, and Ricardo J. Alves de Sousa. "Integrating CAD/CAE/CAM in Engineering Curricula: A Project-Based Learning Approach." Education Sciences 10, no. 5 (April 28, 2020): 125. http://dx.doi.org/10.3390/educsci10050125.

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Problem-based learning (PBL) approaches are well-accepted and disseminated and have been intensively employed in several engineering programs. This article aims to present a teaching experience in which PBL was applied in one course of a mechanical engineering graduation program. The PBL approach applied is described step-by-step as well as the goals and constraints related to Computer-Aided Design, Engineering and Manufacturing (CAD/CAE/CAM) technologies employed in this particular case. The evaluation process is described, as well as the quantitative results, and also the results obtained from questionnaires answered by the students at the end of the PBL experience. Additionally, the team’s technical success in solving the proposed CAD/CAE/CAM problems was also taken into account. This PBL approach provided the students with the required autonomy to develop their argumentative skills within the team, defending their ideas, and at the same time, promoting self-criticism and ethical and impartial judgment among the other team members.
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MORI, Toshihiko, and Suyang Li. "Process Design by Fusion of Process Simulation and Artificial Intelligent." Proceedings of The Manufacturing & Machine Tool Conference 2004.5 (2004): 301–2. http://dx.doi.org/10.1299/jsmemmt.2004.5.301.

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32

Agaev, E. T. "IMPROVING THE QUALITY OF WORKING ALGORITHMS OF CONTROL PROGRAMS OF CNC MACHINES BASED ON A COMPARATIVE ANALYSIS OF MODERN CNC AND CAD/CAM PROGRAMS." Quality. Innovation. Education, no. 5 (2022): 96–101. http://dx.doi.org/10.31145/1999-513x-2022-5-96-101.

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This article discusses the possibility of using modern CNC and CAD / CAM software, to create algorithms for automating the writing of NC for CNC machines, using the example of Sinutrain and Solidworks programs, and also highlights the main quality problems that complicate the process of automating the creation of NC.
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Yan, Bing Bing, G. J. Chen, J. F. Shuai, and D. C. Huang. "Study on CAD/CAM Software System of Machining Spatial Curved Surface by WEDM." Advanced Materials Research 188 (March 2011): 705–10. http://dx.doi.org/10.4028/www.scientific.net/amr.188.705.

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The design, modeling and simulation are one of the key technologies of CAD/CAM software system. The mathematical model of the CAD/CAM system for machining spatial surface was given firstly. After the design idea of the CAD/CAM system was describe in detail, the workflow of the CAD/CAM software system was illustrated, and then data exchange mechanism was determined and detailed steps were given simultaneously. Under MFC framework, the CAD/CAM software system was finished using OpenGL, and the configuration and machining process simulation were carried out. All these works provide an effective approach to raising the productivity and precision of machining spatial curve surface part by WEDM-HS.
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Dai, Ming He, and Zhi Dong Yun. "Application of CAD/CAE/CAM Technology in Plastics Injection Mould Design and Manufacture." Advanced Materials Research 399-401 (November 2011): 2271–75. http://dx.doi.org/10.4028/www.scientific.net/amr.399-401.2271.

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The process of injection mould design and manufacture was introduced by taking the cover as an example. Firstly, the 3D model of the part and the injection mould structure were designed based on SolidWorks software. Secondly, the injection molding progress was analyzed and simulated based on Moldflow software. Finally, the toolpaths of cavity and core were designed based on MasterCAM software, and its manufacture process and numerical control programming was simulated. The period of product development was shortened effectively and the quality of design and manufacture was improved by CAD/CAE/CAM integrated technology.
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35

Porto, T. S., R. C. Roperto, E. A. Campos, S. T. Porto-Neto, and S. Teich. "Behavior of CAD/CAM materials after long thermocycling process." Dental Materials 32 (2016): e33. http://dx.doi.org/10.1016/j.dental.2016.08.068.

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36

Pérez-Cerdán, Juan Carlos, Miguel Lorenzo, Alejandro Reveriego, and Carmen Blanco. "Innovative Approach for Teaching Graphical Engineering Focused on CAD/CAM/CAE Systems." Key Engineering Materials 572 (September 2013): 311–14. http://dx.doi.org/10.4028/www.scientific.net/kem.572.311.

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A new approach of the teaching of the subject Graphical engineering is developed at the Engineering School of the University of Salamanca, focusing the contents on the use of the CAD/CAM/CAE systems as useful tools for applying engineering problems related with the mechanical engineering instead of describing diverse software options. Thus, the contents of the subject are divided into two blocks, one devoted to the analysis of the results of simulation of movement of diverse mechanisms and the second devoted to the analysis of diverse cases of loading structural components by means of FEA module, both available in the Autodesk Inventor Pro suite which can be downloaded free by the students. This way, students can visualize and realize of the complexity of a design process in engineering.
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37

Besnea, Daniel, Georgeta Ionascu, Mihai Avram, Lucian Bogatu, and Alina Spanu. "3D CAD, CAM and Rapid Prototyping Applied for Cam Fabrication." Applied Mechanics and Materials 658 (October 2014): 553–56. http://dx.doi.org/10.4028/www.scientific.net/amm.658.553.

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In this paper, a comparison between CNC manufacturing and Rapid Prototyping technology (FDM – Fused Deposition Modeling process), applied for a cam fabrication, is presented. In the products development area, a substantial support is offered by models, as intermediate between product configuration and technology design. The CAD/CAM/CNC technology is a widely used technique for creating prototypes, as well as production parts, using a subtractive type material-removal procedure from a semi-manufactured article. The rapid prototyping (RP) technologies are additive processes, where the part is built up layer by layer until done, directly from the 3D CAD model, within the precision limits of the chosen process. Similarities and differences between these two coexisting computer driven prototyping processes, the subtractive CNC 3 – axes milled part production and the additive RP/ FDM technique, are pointed out for a disk cam manufacturing as sample part.
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Ibrahim, Musa Alhaji, Huang Kai, and Mustapha Mukhtar Usman. "Application of CAD/CAM in the Design of Machining Process and Tooling Devices for Flange Tube." Jurnal Kejuruteraan 32, no. 1 (February 28, 2020): 17–23. http://dx.doi.org/10.17576/jkukm-2020-32(1)-03.

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Recently, computer-aided design and computer aided manufacturing (CAD/CAM) is largely applied in universal machinery due to the accelerated development of computer technologies. Owing to the technical application of CAD/CAM tool in the manufacturing industry, enterprises have progressively changed their traditional approaches to design and manufacture of products. The CAD module provides product designers with capabilities of designing product model by feature-based design and obtaining product data. The product model is displayed on a screen in the CAD environment before transferring it downstream to the CAM module. This paper presents the application of CAD/CAM in solid modelling, design of machining process, fixture design and virtual manufacture of a flanged tube. Pro/Engineer (Pro/E) Wildfire 4.0 was used to create the three dimensional (3D) model of the flange tube based on its two-dimensional drawing (2D) blank drawing and the mould was designed and created using the same software. The mould creation was based on the clamping and positioning devices of the flange tube being manufactured. The technical schedule of the flange tube was worked out including the choice of machining method, machine tool, cutting tool and selection and computation of machining parameters based on finished drawing the flange tube. Two dedicated fixtures for holding the flange tube in the machine tool were designed and finally Master CAM 9.0 software was applied to the virtual machining of the mould. It is concluded that CAD/CAM tool is important in manufacturing technology as it automates the manufacturing process thereby saving time, energy, cost, and making production highly flexible.
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Ahn, Sung H., V. Sundararajan, Charles Smith, Balaji Kannan, Roshan D’Souza, Ganping Sun, Ashish Mohole, et al. "CyberCut: An Internet-based CAD/CAM System." Journal of Computing and Information Science in Engineering 1, no. 1 (January 1, 2001): 52–59. http://dx.doi.org/10.1115/1.1351811.

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“CyberCut™” is a testbed for an Internet-based CAD/CAM system. It was specifically designed to be a networked, automated system, with a seamless communication flow from a client-side designer to a server-side machining service. The creation of CyberCut required several new software modules. These include: a) a Web-based design tool in which Design-for-Manufacturing information and machining rules constrain the designer to manufacturable parts; b) a geometric representation called SIF-DSG, for unambiguous communication between the client-side designer and the server-side process planner; c) an automated process planning system with several sub-modules that convert an incoming design to a set of tool-paths for execution on a 3-axis CNC milling machine. Using this software-pipeline, a CyberCut service, modeled on the MOSIS service for VLSI chips, has been now been launched for limited student-use at a group of cooperating universities.
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Jiao, Zhong Fei, Shan Yao, Shu Ming Zhao, Feng Zeng, and Di Wu. "A Digital Near Net Shape Manufacturing Propeller with Complex Surface." Advanced Materials Research 201-203 (February 2011): 117–20. http://dx.doi.org/10.4028/www.scientific.net/amr.201-203.117.

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An integrated digital routine is applied in the near net shape manufacturing of marine propeller. Firstly, the 3D CAD file of propeller is created by parametric modeling. Secondly, the propeller casting process is simulated using CAE software, through which an optimized casting scheme is obtained. Thirdly, fabricates the mold using laser rapid prototyping and cast the metal propeller. Finally, evaluate the casting precision performance. CAD, CAE and CAM are integrated in this process. The dimensional accuracy of the final piece is controlled within 1mm and its surface roughness achieves Ra 6.3μm. The result shows that the pattern-less casting of propeller can be achieved by this method, reducing cost and performing high accuracy.
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Gao, Hui Qin. "Integrated Design on CAD/CAM/CAPP/CNC for Cam Mechanism." Applied Mechanics and Materials 602-605 (August 2014): 614–18. http://dx.doi.org/10.4028/www.scientific.net/amm.602-605.614.

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In Pro/E environment, it gived the details about parameteric designs on cam contour curve. By 3D parameterized modeling, motion simulation and analysis of cam, the process planning and tool travel-paths generating were given. G-Codes program was automatically generated too. At last, the integrated design on CAM/CAPP/CNC for cam components is realized.
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42

Bond, Alan H. "A predicate logic approach to CAD/CAM modeling." Artificial Intelligence for Engineering Design, Analysis and Manufacturing 6, no. 1 (February 1992): 39–58. http://dx.doi.org/10.1017/s0890060400002936.

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An approach to CAD and CAM modeling and to the design of CAD/CAM systems is presented. Models of the product and of the process are represented by logical assertions in a common logical language. CAD/CAM functions are represented by the application of logical inference rules, which correspond to the derivation of new information as well as to actions. This allows all the different kinds of model and specification used in design and manufacturing to be represented in a computer in a common form. It therefore allows the representation of constraints and rules connecting any aspects of design and manufacturing together.This approach has all the advantages of formal specifiction, namely, ease of expression, communication, standardization and abstraction. At the same time, we demonstrate its practical implementation in an efficient form, and which is industry compatible, and we report practical experience with using this approach for CAD/CAM models and for intelligent CAD/CAM functions.
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Antkowiak, Tomasz, and Marcin Kruś. "Contemporary Methods of Designing Rail Vehicle Running Systems with the Use of CAD and CAM Solutions." Problemy Kolejnictwa - Railway Reports 64, no. 187 (June 2020): 75–80. http://dx.doi.org/10.36137/1871e.

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The article discusses the process of designing the running system of a rail vehicle using CAD and CAM tools as the solutions supporting the process. It describes the particular stages of design taking its final shape: from a preliminary design, through a detailed design, ending with the stage of production. Each stage includes a presentation of how CAD and CAM tools are used to support design engineers in their practice. Keywords: running system, design, CAD, CAM
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44

Spitznagel, F. A., J. Boldt, and P. C. Gierthmuehlen. "CAD/CAM Ceramic Restorative Materials for Natural Teeth." Journal of Dental Research 97, no. 10 (June 15, 2018): 1082–91. http://dx.doi.org/10.1177/0022034518779759.

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Advances in computer-aided design (CAD) / computer-aided manufacturing (CAM) technologies and their ease of application enabled the development of novel treatment concepts for modern prosthodontics. This recent paradigm shift in fixed prosthodontics from traditional to minimally invasive treatment approaches is evidenced by the clinical long-term success of bonded CAD/CAM glass-ceramic restorations. Today, defect-oriented restorations, such as inlays, onlays, and posterior crowns, are predominately fabricated from glass-ceramics in monolithic application. The variety of CAD/CAM ceramic restorative systems is constantly evolving to meet the increased demands for highly aesthetic, biocompatible, and long-lasting restorations. Recently introduced polymer-infiltrated ceramic network CAD/CAM blocks add innovative treatment options in CAD/CAM chairside 1-visit restorations. The material-specific high-edge stability enables the CAD/CAM machinability of thin restoration margins. Full-contour zirconia restorations are constantly gaining market share at the expense of bilayered systems. Advancements in material science and bonding protocols foster the development of novel material combinations or fabrication techniques of proven high-strength zirconia ceramics. CAD/CAM applications offer a standardized manufacturing process resulting in a reliable, predictable, and economic workflow for individual and complex teeth-supported restorations. More evidence from long-term clinical studies is needed to verify the clinical performance of monolithic polymer-infiltrated ceramic network and zirconia teeth-supported minimally invasive and extensive restorations.
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Kamsyah, Domi, Ari Kurniadi, Benny Haddli Irawan, Rahman Hakim, and Saiful Arif. "Integration System of CAD/CAM In Machinary Process Using Wire-EDM." Jurnal Teknologi dan Riset Terapan (JATRA) 3, no. 1 (June 30, 2021): 21–26. http://dx.doi.org/10.30871/jatra.v3i1.3050.

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Computer-Aided Design (CAD) and Computer-Aided Manufacturing (CAM) are usually used to draw sketches and model manufacturing work processes on machines that operate using computer numerical control (CNC). To communicate with each other CAD and CAM must have the same format, the drawings produced by CAD must the same format to be run on the CAM. In this study, product images will be created using Autocad software and it will run on the Fikus VisualCAM 19 software to visualize the tool pathway. The program is created to run a CNC machine and the resulting product will check the conformity of its dimensions and geometry. The results obtained are that the images generated from the AutoCAD software can run well on the Fikus VisualCAM 19 software. The program in the form of NC code generated by AutoCAD and Fikus VisualCAM19 software can be run properly by a CNC wire-cutting EDM machine, this can be seen from the product results that match the dimensions and geometry.
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46

Buduru, Smaranda, Oana Almasan, Marius Todea, Loredana Mitariu, Mihai Mitariu, Mariana Pacurar, and Manuela Taut. "Conventional compared to CAD/CAM ceramic inlay." Romanian Journal of Stomatology 68, no. 2 (June 30, 2022): 82–89. http://dx.doi.org/10.37897/rjs.2022.2.6.

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Objectives. This study aimed at comparing the methodologies for achieving an occlusal-mesial ceramic inlay using both the conventional and digital methods in terms of workflow protocol, aesthetic and functional results, working time, but also costs and equipment needed. Material and methods. A 22-year-old patient presented with a direct mesio-occlusal composite restoration with a secondary marginal decay in tooth 3.6 that was subsequently restored by a ceramic inlay manufactured using both traditional and digital methods. Outcomes. The dental technician's talent, experience, and vision guided the technical process of creating the conventional inlay. The technical process of producing the digital inlay involved fewer laboratory stages, but also contamination risks than conventional ones, removing potential human errors associated with each stage and allowing possible changes to be made more quickly and efficiently. The conventional method took more time to complete all of the laboratory steps than the digital method. Conclusions. When compared to the digital method, the traditional method allowed the dental technician to achieve a high level of individualization of the prosthetic restoration. Digital techniques are a method of the future that is rapidly growing and improving. Digital techniques for obtaining an inlay involved high-performance equipment, which is pricey to purchase and maintain.
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Pathak, Nimai, Bhagyalaxmi Chundawat, Pratik Das, Pampa Modak, and Brindaban Modak. "Unraveling the site-specific energy transfer driven tunable emission characteristics of Eu3+ & Tb3+ co-doped Ca10(PO4)6F2 phosphors." RSC Advances 11, no. 50 (2021): 31421–32. http://dx.doi.org/10.1039/d1ra04941k.

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Various site specific energy transfer (ET) process such as Tb3+@Ca2 → Eu3+@Ca1, Tb3+@Ca1 → Eu3+@Ca2 and Tb3+@Ca1 → Eu3+@Ca1 were explored in Eu3+ and Tb3+ co-doped Ca10(PO4)6F2 phosphor, which are responsible for tunable colour characteristics.
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48

Wibisono, Galih, Bernardus Sentot Wijanarka, and Habanabakize Theophile. "The Link and Match between the Competency of Vocational High Schools Graduates and the Industry on CAD/ CAM and CNC." Jurnal Pendidikan Teknologi dan Kejuruan 26, no. 1 (April 23, 2020): 26–34. http://dx.doi.org/10.21831/jptk.v26i1.27932.

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This study describes (1) the work process analysis of the production stage in the industry, (2) the required competency and skills of CAD/ CAM and CNC in the industry, (3) the implementation of the basic competency of CAD/ CAM and CNC in vocational high schools, (4) the link and match between the competency of vocational high schools graduates and the industry on CAD/ CAM and CNC. The descriptive-qualitative method was employed by involving 8 people from Mega Andalan Kalasan Ltd (MAK) and 5 people from vocational high schools. The data were collected through observation and interviews which were further analyzed descriptively. The findings indicate (1) the work process analysis map the competencies that must be owned by the workforce including CAD drafter, CAM programmer, and CNC operators in which each workforce involved 4 work process sequences, (2) the competency of CAD/ CAM and CNC described the knowledge and psychomotor activities. In detail, the activity of the CNC machine setting produced knowledge competence and the skills of 36.5% and 26.7% respectively. The operating CNC machine produced the knowledge competence and skills of 25.4% and 23.3% respectively. The 3D drawing and 2D CAD systems produced the knowledge competence and skills of 19% and 23.3% respectively, CAM Programming generated the knowledge competence and skills of 19% and 26.7% respectively, (3) the implementation of basic competencies can be categorized as good, (4) there are two competencies fulfilled the link and match between the vocational high schools' competencies and industry, namely manufacturing drawing competency with CAD as well as mechanical competency with CNC and CAM.
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49

Okesina, A. A., M. S. Ajao, M. O. Buhari, A. M. Afodun, K. B. Okesina, R. Y. Usman, F. A. Sulaimon, and B. P. Kolawole. "Activation of pro-apoptotic cells, reactive astrogliosis and hyperphosphorylation of tau protein in trimethyltin-induced hippocampal injury in rats." Anatomy Journal of Africa 9, no. 2 (August 21, 2020): 1782–88. http://dx.doi.org/10.4314/aja.v9i2.198924.

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Neurodegenerative diseases cause neural cells to lose both the functional and sensory abilities as a result of genetic factors, proteopathies and mitochondrial dysfunction. Neurodegeneration forms the basis of most neurodegenerative disorders for example Alzheimer’s disease, Huntington’s diseases, and Parkinson’s diseases. The mechanism that underlines the process of neurodegeneration is not well understood. Understanding the process and mechanism involved in neurodegeneration might offer a better therapeutic approach to positively manage cases of neurodegenerative diseases. Therefore, this study’s target was to create an animal model to study neurodegeneration. Sixteen adult male Wistar rats were used in the study and divided into two groups. Control (0.2 mL of normal saline (NS)), and trimethyltin-treated (TMT, 8 mg/kg stat dose only). These animals underwent perfusion with 4% paraformaldehyde, brain excision and analysis of p53 antigen, GFAP and Bielshowsky on these tissues. The results showed that animals in the control group showed presence of activated p53 antigen, reactive astrogliosis, neurofibrillary tangles, and amyloid plaques within the cytoplasm of the hippocampal cells. Cornus Ammonis (CA2) and (CA3) showed more of the trimethylrtin injury than CA1 and CA4. This study thus revealed that, intra-peritoneal administration of single dose of 8mg/kg of trimethyltin can offer an attractive disease model to study some neurodegenerative diseases. Keywords: p53 antigen, Bielshowsky, Glia fibrillary acidic protein, Trimethyltin, Hippocampus,
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Pollak, Martin, Petr Baron, and Jozef Zajac. "AUTOMATIZATION PROCESS OF DESIGNING THE TECHNOLOGICAL DOCUMENTATION BY TOOLS OF COMPREHENSIVE CAD-CAM-CAE SYSTÉM." MM Science Journal 2016, no. 03 (September 7, 2016): 942–46. http://dx.doi.org/10.17973/mmsj.2016_09_201630.

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