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Journal articles on the topic 'Prenatal stage'
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Muktar, Mujiburrahman, Tarmidi, Masrur, Fajrurrahman, and Suci Faradilla. "Existence of Pranatal Education in Islam." Britain International of Linguistics Arts and Education (BIoLAE) Journal 1, no. 2 (November 30, 2019): 210–23. http://dx.doi.org/10.33258/biolae.v1i2.88.
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Prenatal education is often ignored in daily life. Though this education is highly recommended by religion for adherents of his religion. But to socialize prenatal education in social life today, it is necessary to re-actualize knowledge about the existence of prenatal education. Community life will gradually improve by paying attention to prenatal education as one of the needs in educating children from the womb in an Islamic perspective. There are two problems that must be answered in this paper are the stages of human creation and the concept of prenatal education in Islam. This research is in the form of library research, in which the research aims to describe the meaning on the basis of understanding the reading material sourced from the literature which has a close relationship with the problems presented in this paper using descriptive qualitative methods aimed at describing and analyzing phenomena and concepts using words not numbers. This study aims to determine: the development of prenatal age children, the concept of Pranatal education in Islam. The data collection technique used is to examine a number of primary and secondary data sources. Data analysis techniques by means of text analysis (content analyst). The results showed that: 1. The development of a prenatal child during her mother's womb includes three stages, including the Nuthfah stage in the form of male sperm and female egg cells that meet in the womb and fertilization occurs. The second stage ‘Alaqah (a clot of blood) even though the body tissue has begun to form, the next stage is the Mudghah (a lump of flesh), at this time in the form of a fetus that has been perfect and lives with spirits blown by angels. 2. The concept of prenatal education includes 3 stages: first, the preconception period (partner selection), second, the postconception period (marriage / copulation), third, the pre-natal period (pregnancy). Based on the results of this study is expected to be an information or input to parents to pay more attention to education to children, especially educating children since in the womb, based on certain concepts and methods with the hope that children born will become human figures who have noble personality, as expected.
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Ivry, Tsipy. "At the Back Stage of Prenatal Care: Japanese Ob-Gyns Negotiating Prenatal Diagnosis." Medical Anthropology Quarterly 20, no. 4 (December 2006): 441–68. http://dx.doi.org/10.1525/maq.2006.20.4.441.
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Yuliani, Nur Rohmah, and Setiana Andarwulan. "Efficacy of Prenatal Yoga on Second Stage Progress in Third Trimester Pregnant Women." International Journal of Clinical Inventions and Medical Sciences 4, no. 2 (August 28, 2022): 56–61. http://dx.doi.org/10.36079/lamintang.ijcims-0402.408.
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The study about the efficacy of yoga on second stage progress in third trimester pregnant. Labor is a journey process that will be experienced by pregnant women at the end of pregnancy after entering the age of 36 weeks under normal conditions. Labor will cause feelings of worry for a mother, but childbirth can be passed safely and comfortably without trauma. Prenatal yoga is considered as an alternative to non-conventional efforts to help pregnant women prepare physically, mentally and spiritually for the birth process. This study aims to determine the effect of prenatal yoga on the length of the second stage of labor at Mitra Sehat Mandiri Clinic. The study was conducted with an analytical design with a quasi-experimental primigravida method in the third trimester with a sample of 30 pregnant women who were divided into two groups, namely 15 maternity mothers who attended prenatal yoga and 15 who did not participate in prenatal yoga. Data analysis used independent t statistical test. The average length of the second stage of labor for women who took part in prenatal yoga was 21.66 with a standard deviation of 1.17, while those who did not do yoga were 42.76 with a standard deviation of 2.98. The conclusion is that there is an effect of third trimester yoga exercise on the length of the second stage of labor in mothers with P value = 0.000. Mothers who practice prenatal yoga before delivery will be better prepared to face labor, focus their thoughts and provide inner peace.
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Kozol, Robert. "Prenatal Neuropathologies in Autism Spectrum Disorder and Intellectual Disability: The Gestation of a Comprehensive Zebrafish Model." Journal of Developmental Biology 6, no. 4 (November 30, 2018): 29. http://dx.doi.org/10.3390/jdb6040029.
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Autism spectrum disorder (ASD) and intellectual disability (ID) are neurodevelopmental disorders with overlapping diagnostic behaviors and risk factors. These include embryonic exposure to teratogens and mutations in genes that have important functions prenatally. Animal models, including rodents and zebrafish, have been essential in delineating mechanisms of neuropathology and identifying developmental critical periods, when those mechanisms are most sensitive to disruption. This review focuses on how the developmentally accessible zebrafish is contributing to our understanding of prenatal pathologies that set the stage for later ASD-ID behavioral deficits. We discuss the known factors that contribute prenatally to ASD-ID and the recent use of zebrafish to model deficits in brain morphogenesis and circuit development. We conclude by suggesting that a future challenge in zebrafish ASD-ID modeling will be to bridge prenatal anatomical and physiological pathologies to behavioral deficits later in life.
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Evans, William N., Ruben J. Acherman, Michael L. Ciccolo, Juan Lehoux, Alvaro Galindo, Abraham Rothman, Gary A. Mayman, and Humberto Restrepo. "Stage-1 Hybrid Palliation for High-Risk 2-Ventricle Patients with Ductal-Dependent Systemic Circulation in the Era of High Prenatal Detection." World Journal for Pediatric and Congenital Heart Surgery 12, no. 6 (November 2021): 754–59. http://dx.doi.org/10.1177/21501351211044417.
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Objective We reviewed our center's prenatal detection and surgical experience with high-risk, 2-ventricle patients, with complex congenital heart disease that underwent stage-1 hybrid palliation. Methods We retrospectively identified those born between March 2008 and March 2021 with 2-ventricle hearts, complex congenital cardiovascular malformations, and ductal-dependent systemic circulation that underwent stage-1 hybrid palliation consisting of surgical bilateral pulmonary artery banding and interventional catheterization placed ductus arteriosus stents. Results We identified 30 patients. Of the 30, 19 (63%) were male. For the 30, median gestational age was 35 weeks (29-39 weeks), and median birth weight was 2.2 kg (0.6-4.5 kg). Of the 30, 1 was transferred from an adjacent state, and 29 were born in Nevada. Of the 29 born in Nevada, overall statewide prenatal detection was 18 of 29 (62%); however, for 2008 to 2011 the prenatal detection rate was 3 of 10 (30%) and 15 of 19 (79%) for 2012 to 2021, P = .03. For the last 5 years, prenatal detection for Nevada-born patients was 8 of 8 (100%). Two full-term newborns, without a prenatal diagnosis, presented postnatally in extremis. For the 30 patients, there were 0 stage-1 hybrid palliation mortalities, 1 subsequent repair mortality, and 3 late nonsurgical deaths. Conclusions Stage-1 hybrid palliation may result in excellent surgical outcomes for high-risk, 2-ventricle patients. Additionally, high rates of population-wide prenatal detection are possible for high-risk congenital heart disease, allowing prenatal planning and possibly reducing postnatal extremis presentations.
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Fatmayanti, Aulia, Septalia Isharyanti, and Erna Widyastuti. "Effectiveness Of Prenatal Yoga On The Level Of Anxiety And Long-Time Labor On Maternity Primiparous." Journal of Midwifery Science: Basic and Applied Research 1, no. 1 (October 24, 2019): 21–24. http://dx.doi.org/10.31983/jomisbar.v1i1.5342.
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The process of delivering on each mother must be different. Apparently, in addition to be the cause of the clinical, psychological atmosphere of the mother who does not support also contribute to complicate the process ofchildbirth. As a mother in a state of anxiety, excessive worry and fear, until eventually lead to stress. The purpose of the research was to determine the effectiveness of prenatal yoga on anxiety level and the second stage of labor longer on maternity primiparous. Methods research with quantitative approachquasi experimental with control grou pdesign. The total sample of 20 respondents, each group of 10 respondents. Bivariate analysis is done in two variables: the old stage II with categorical scale so usingtest. chi-square Jikasyaratchi-squareis not met using the Fisher exactprovided that if the value sig(p)0.05 then say no relationship signifikan.dan anxiety level has a categorical scale, if it does not qualifytest chi-square then used thealternative test Kolmogorov- Smirnov. The results of the study was prenatal yoga is proven effective against anxiety levels in maternal primipara withvalue significancy 0,003and prenatal yoga are effective against the second stage of labor longer on maternity primipara withvalue of significancy 0.003. Prenatal yoga is proven effective against anxiety levels in maternal and prenatal yoga primiparous effective against second stage of labor longer in primiparous birthmothers.
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Götz, Ilse, and Manfred Götz. "How and Why Parents Change Their Attitudes to Prenatal Diagnosis." Clinical Child Psychology and Psychiatry 11, no. 2 (April 2006): 293–300. http://dx.doi.org/10.1177/1359104506061447.
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Parents who know they are carriers of a genetically transmitted disease because they gave birth to an affected child are being offered a number of reproductive options in a subsequent pregnancy. We describe the attitudes and motives of parents of children with cystic fibrosis (CF) who were initially determined to use prenatal testing but eventually refused it. Based on our observations and clinical impressions we built a model of change that entails a series of stages and depicts change as a process. This begins with the provision of comprehensive information and emotional support through health professionals (Stage 1). The parents then engage in intense confrontation with the impact of prenatal testing and are exposed to influences from many sides. The repeated comparing of the arguments results in uncertainty and distress (Stage 2). When pregnancy occurs a decision must be made and the process culminates in participating in a life-or-death decision. If the parents cannot cope with that responsibility then a change towards rejection of prenatal diagnosis is likely (Stage 3). This phenomenon seems to be the most decisive factor. A case vignette is used to illustrate this model which may be applicable to many individuals who face major and emotionally fraught decisions.
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Berghuis, Sietske A., Arend F. Bos, Henk Groen, Wilhelmina H. A. de Jong, Anneke C. Muller Kobold, Lucie Wagenmakers-Huizinga, Pieter J. J. Sauer, and Gianni Bocca. "Prenatal Environmental Exposure to Persistent Organic Pollutants and Reproductive Hormone Profile and Pubertal Development in Dutch Adolescents." International Journal of Environmental Research and Public Health 19, no. 15 (August 1, 2022): 9423. http://dx.doi.org/10.3390/ijerph19159423.
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Persistent organic pollutants (POPs), such as polychlorinated biphenyls (PCBs), may interfere with hormonal processes. Knowledge about the effects of prenatal exposure to PCBs and their hydroxylated metabolites (OH-PCBs) on pubertal development is limited. Therefore, the aim of the current study was to determine whether prenatal environmental PCB and OH-PCB exposure are associated with reproductive hormone levels and pubertal characteristics in 13- to 15-year-old children. In this Dutch observational cohort study, 194 mother–infant pairs were included (1998–2002). Maternal pregnancy serum levels of PCBs, OH-PCBs, and other POPs were measured. At follow-up (2014–2016), we measured serum or plasma levels of reproductive hormones in their children. We assessed Tanner stages and testicular volume (by clinician or standardized self-assessment), and participants completed questionnaires on pubertal onset. In total, 101 adolescents (14.4 ± 0.8 years; 53.7% of invited) participated, and 55 were boys. In boys, higher prenatal PCB levels were associated with higher testosterone levels, higher pubic hair stage, larger testicular volume, and younger age at onset of growth spurt and voice break. In girls, higher prenatal PCB levels were associated with higher stages for breast development. In conclusion, higher prenatal PCB exposure could be associated with more advanced pubertal development in 13- to 15-year-old children.
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Iwadate, Hiromoto, Motoshige Kudo, and Kazuyuki Kizuki. "Expression of tissue kallikrein mRNA in developing rat brains." Canadian Journal of Physiology and Pharmacology 80, no. 4 (April 1, 2002): 245–48. http://dx.doi.org/10.1139/y02-026.
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Immunoreactive kallikrein has been demonstrated in the neurons of both prenatal and adult rat brains. However, the preferential site is quite different between the prenatal and adult brains, i.e., the former is mainly in the nuclei, and the latter is in the cell bodies and processes. In this study, the intensity of kallikrein mRNA expression was investigated in prenatal and postnatal rat brains by reverse transcription polymerase chain reaction (RT-PCR). A marked progressive increase in kallikrein mRNA expression was observed during the prenatal and early postnatal stage, with the maximum level at postnatal days 0 and 1 (P0 to P1). This helps to explain the previous immunohistochemical findings in which a strong immuno-intensity of kallikrein in the neurons of prenatal and newborn rat brains was found as compared with adult rats. The function(s) of kallikrein expressed in the neurons in the developing stages is unclear, but the role(s) must be different from that of the adult because of the unequivocal difference in its location between them. It is thus possible that kallikrein has certain unknown important role(s) in the neuronal physiology acting on nuclear protein(s) in the developing stages, although the possibility of function via kinin receptors cannot be excluded at present.Key words: kallikrein, kinin receptor, brain, neuron, mRNA.
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Johnson, Jennifer J., Weili Chen, Wendy Hudson, Qing Yao, Marnie Taylor, Terence H. Rabbitts, and John H. Kersey. "Prenatal and postnatal myeloid cells demonstrate stepwise progression in the pathogenesis of MLL fusion gene leukemia." Blood 101, no. 8 (April 15, 2003): 3229–35. http://dx.doi.org/10.1182/blood-2002-05-1515.
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Abstract The steps to leukemia following an in utero fusion ofMLL (HRX, ALL-1) to a partner gene in humans are not known. Introduction of the Mll-AF9 fusion gene into embryonic stem cells results in leukemia in mice with cell-type specificity similar to humans. In this study we used myeloid colony assays, immunophenotyping, and transplantation to evaluate myelopoiesis in Mll-AF9 mice. Colony assays demonstrated that both prenatal and postnatal Mll-AF9 tissues have significantly increased numbers of CD11b+/CD117+/Gr-1+/− myeloid cells, often in compact clusters. The self-renewal capacity of prenatal myeloid progenitors was found to decrease following serial replating of colony-forming cells. In contrast, early postnatal myeloid progenitors increased following replating; however, the enhanced self-renewal of early postnatal myeloid progenitor cells was limited and did not result in long-term cell lines or leukemia in vivo. Unlimited replating, long-term CD11b/Gr-1+ myeloid cell lines, and the ability to produce early leukemia in vivo in transplantation experiments, were found only in mice with overt leukemia. Prenatal Mll-AF9tissues had reduced total (mature and progenitor) CD11b/Gr-1+ cells compared with wild-type tissues. Colony replating, immunophenotyping, and cytochemistry suggest that any perturbation of cellular differentiation from the prenatal stage onward is partial and largely reversible. We describe a novel informative in vitro and in vivo model system that permits study of the stages in the pathogenesis of Mll fusion gene leukemia, beginning in prenatal myeloid cells, progressing to a second stage in the postnatal period and, finally, resulting in overt leukemia in adult animals.
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Sathanandam, Shyam K., Ranjit Philip, David Gamboa, Andrew Van Bergen, Michel N. Ilbawi, Christopher Knott-Craig, B. Rush Waller, Alexander J. Javois, and Bettina F. Cuneo. "Management of hypoplastic left heart syndrome with intact atrial septum: a two-centre experience." Cardiology in the Young 26, no. 6 (September 8, 2015): 1072–81. http://dx.doi.org/10.1017/s1047951115001791.
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AbstractIntroductionHypoplastic left heart syndrome with an intact atrial septum is a poor predictor of outcomes. Prenatal assessment of pulmonary venous Doppler and emergent postnatal cardiac intervention may be associated with better outcomes.Materials and methodsA retrospective review of all hypoplastic left heart syndrome patients in two centres over a 5-year period was performed. Group 1 included patients with adequate inter-atrial communication. Group 2 included patients with prenatal diagnosis with an intact atrial septum who had immediate transcatheter intervention. Group 3 included patients with intact atrial septum who were not prenatally diagnosed and underwent either delayed intervention or no intervention before stage 1 palliation. Primary outcome was survival up to stage 2 palliation.ResultsThe incidence of hypoplastic left heart syndrome with a restrictive atrial communication was 11.2% (n=19 of 170). Overall survival to stage 2 or heart transplantation was 85% and 67% for Groups 1 and 2, respectively (n=129/151, n=8/12; p=0.03), and 0% (n=0/7) for Group 3. Survival benefits were observed between Groups 2 and 3 (p<0.001). Foetal pulmonary vein Doppler reverse/forward velocity time integral ratio of ⩾18% (sensitivity, 0.99, 95% CI, 0.58–1; specificity, 0.99, 95% CI, 0.96–1) was predictive of the need for emergent left atrial decompression.ConclusionUsing a multidisciplinary approach and foetal pulmonary vein Doppler, time-saving measures can be instituted by delivering prenatally diagnosed neonates with hypoplastic left heart syndrome with intact atrial septum close to the cardiac catheterisation suite where left atrial decompression can be performed quickly and safely that may improve survival.
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Leake, David W. "Tracing Slow Phenoptosis to the Prenatal Stage in Social Vertebrates." Biochemistry (Moscow) 87, no. 12-13 (December 2022): 1512–27. http://dx.doi.org/10.1134/s0006297922120094.
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Abstract Vladimir Skulachev’s coining of the term “phenoptosis” 25 years ago (Skulachev, V. P., Biochemistry (Moscow), 62, 1997) highlighted the theoretical possibility that aging is a programmed process to speed the exit of individuals posing some danger to their social group. While rapid “acute phenoptosis” might occur at any age (e.g., to prevent spread of deadly infections), “slow phenoptosis” is generally considered to occur later in life in the form of chronic age-related disorders. However, recent research indicates that risks for such chronic disorders can be greatly raised by early life adversity, especially during the prenatal stage. Much of this research uses indicators of biological aging, the speeding or slowing of natural physiological deterioration in response to environmental inputs, leading to divergence from chronological age. Studies using biological aging indicators commonly find it is accelerated not only in older individuals with chronic disorders, but also in very young individuals with health problems. This review will explain how accelerated biological aging equates to slow phenoptosis. Its occurrence even in the prenatal stage is theoretically supported by W. D. Hamilton’s proposal that offsprings detecting they have dangerous mutations should then automatically speed their demise, in order to improve their inclusive fitness by giving their parents the chance to produce other fitter siblings.
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Shramova, O. "The right to health of the child in prenatal stage." Часопис Київського університету права, no. 4 (2017): 50–60.
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Pandey, S., M. Naassila, E. S. O'Brien, V. Warnault, R. Legastelois, B. Botia, C. Vilpoux, et al. "S31 * EPIGENETIC MECHANISMS OF ALCOHOLISM: FROM PRENATAL STAGE TO ADULTHOOD." Alcohol and Alcoholism 48, suppl 1 (August 12, 2013): i31—i32. http://dx.doi.org/10.1093/alcalc/agt109.
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Franciska, Yunetra, Aprillia Ayu Shinta Yuka, and Wilma Wilma. "Relieve Labor Pain With Hypno Prenatal and Prenatal Yoga." Jurnal Ilmu dan Teknologi Kesehatan 9, no. 1 (September 30, 2021): 60–70. http://dx.doi.org/10.32668/jitek.v9i1.579.
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Pregnancy and childbirth are physiological processes that every woman will go through. The intensity of pain experienced by women during labor varies, but it can be exacerbated by fear, tension, and anxiety. Hypnosis techniques have been proposed as a means of overcoming anxiety and fear. Compared to women who receive relaxation training or supportive counselling, hypnosis reduces pain intensity, shortens delivery time, and reduces the number of women who stay in the hospital for more than two days after their baby is born. Yoga during pregnancy, like hypnosis, has been shown to reduce pain intensity during the first stage of labor. This research aimed to see how prenatal hypnosis and prenatal yoga affected labor pain in women giving birth at the Independent Practice of Midwife Meli Rosita Palembang. This study employs an experimental research design with a Static Group Comparison strategy. The sample in this study consisted of 60 pregnant women divided into two groups: those who received hypnosis and prenatal yoga interventions and those who did not. Questionnaires, checklists, and tutorials on implementing prenatal hypnosis and prenatal yoga were used as instruments. Prenatal hypnosis and prenatal yoga significantly affected labor pain in Maternal Maternity at Meli Rosita's Independent Midwife Practice (p-value 0.000). The intervention group had a pain scale average of 2.70, while the control group had a pain scale average of 4.33. As a result, a combination of prenatal hypnosis and prenatal yoga can alleviate labor pain.
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Franciska, Yunetra, Aprillia Ayu Shinta Yuka, and Wilma Wilma. "Relieve Labor Pain With Hypno Prenatal and Prenatal Yoga." Jurnal Ilmu dan Teknologi Kesehatan 9, no. 1 (September 30, 2021): 60–70. http://dx.doi.org/10.32668/jitek.v9i1.579.
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Pregnancy and childbirth are physiological processes that every woman will go through. The intensity of pain experienced by women during labor varies, but it can be exacerbated by fear, tension, and anxiety. Hypnosis techniques have been proposed as a means of overcoming anxiety and fear. Compared to women who receive relaxation training or supportive counselling, hypnosis reduces pain intensity, shortens delivery time, and reduces the number of women who stay in the hospital for more than two days after their baby is born. Yoga during pregnancy, like hypnosis, has been shown to reduce pain intensity during the first stage of labor. This research aimed to see how prenatal hypnosis and prenatal yoga affected labor pain in women giving birth at the Independent Practice of Midwife Meli Rosita Palembang. This study employs an experimental research design with a Static Group Comparison strategy. The sample in this study consisted of 60 pregnant women divided into two groups: those who received hypnosis and prenatal yoga interventions and those who did not. Questionnaires, checklists, and tutorials on implementing prenatal hypnosis and prenatal yoga were used as instruments. Prenatal hypnosis and prenatal yoga significantly affected labor pain in Maternal Maternity at Meli Rosita's Independent Midwife Practice (p-value 0.000). The intervention group had a pain scale average of 2.70, while the control group had a pain scale average of 4.33. As a result, a combination of prenatal hypnosis and prenatal yoga can alleviate labor pain.
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Mostafa, Mohamed, Mesbah El-Sayed, Salah Farag, and Galal Youssef. "Prenatal Development of Incisors in the Egyptian Buffalo (Bos bubalis)." Mansoura Veterinary Medical Journal 21, no. 3 (September 29, 2020): 80–84. http://dx.doi.org/10.35943/mvmj.2020.21.314.
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Objective: The teeth play important roles in food mastication, prehension and defense against predators. Although several studies demonstrated the development of teeth in different mammalian species, no data are, to our knowledge, available in Egyptian buffalos. Therefore, the present investigation was conducted to study the development of incisor teeth in buffaloe. Design: Descriptive study. Animals: seventeen buffalo embryos and fetuses of both sexes were used. Their crown vertebral rump lengths (CVRL) ranged from 2 to 46 cm (equivalent to 38 - 177 days old). Procedure: Embryos and fetuses were fixed in 10% neutral buffered formalin and decalcified by 14% EDTA solution for several weeks. The samples were dehydrated, cleared and embedded in paraffin wax using standard techniques. Sections were cut on Leitz microtome and mounted on uncoated slides. For general histological structure, a selection of slides was routinely stained with haematoxylin–eosin and examined by the light microscope. Result: The present study reported for the first time that the prenatal development of incisors in buffalo passes through three sequential stages: the bud, cap and bell stages. Although each stage was easily differentiated based on its form and its distinct developmental features, the three stages were overlapped with each other’s. Generally, the bud stage was observed in 11 cm CVRL buffalo fetuses, meanwhile the cap and bell stages were detected in 23 cm and 30 cm CVRL fetuses respectively. Conclusion and clinical relevance: These results can be used as inductive index for determination of the ages of buffalo embryos and fetuses.
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Evans, Na’Tasha M., Kamesha Spates, and Jiunn-Jye Sheu. "How My Provider Communicates: A Qualitative Exploration of Pregnant Women’s Communicative Experiences When Receiving Prenatal Care in Ohio." Ohio Journal of Public Health 3, no. 2 (October 1, 2020): 5–13. http://dx.doi.org/10.18061/ojph.v3i2.9010.
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Background: Ohio disproportionately has one of the highest infant mortality rates in the United States. Failure to receive effective prenatal care can result in adverse pregnancy outcomes, specifically infant morbidity and mortality. Therefore, the purpose of this study is to gain a better understanding of pregnant women’s communicative experiences when receiving prenatal care in Ohio. Methods: We interviewed pregnant women (N=30) between the ages of 19 to 39 years who were in the second or third trimester of pregnancy residing in Ohio using semi-structured interviews. The data were analyzed using a two-stage inductive thematic analytic technique. Results: Findings demonstrated that pregnant women’s communicative experiences when receiving prenatal care in Ohio could be categorized into 4 overarching salient themes: (1) dialogue with the prenatal care provider, (2) time required for the prenatal care visit, (3) the prenatal care provider’s interpersonal and personality characteristics, and (4) continuity of care. Conclusion: Results identified pregnant women’s communicative experiences when receiving prenatal care in Ohio. Findings may assist prenatal care providers in enhancing prenatal care outcomes in Ohio by promoting continuous dialogue, spending time with patients, displaying positive interpersonal and personality characteristics, and providing continuous prenatal care.
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Noviani, Ni Wayan, and Ni Wayan Sukma Adnyani. "Pengaruh prenatal yoga terhadap lama kala II persalinan dan kejadian robekan perinium." Jurnal Kebidanan 9, no. 2 (August 31, 2020): 115. http://dx.doi.org/10.26714/jk.9.2.2020.115-122.
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Labor is assumed to be a painful and tense process, but labor can be passed with a sense of security and comfort without trauma. Yoga is considered one of the alternative therapies to prepare pregnant women physically, mentally, and spiritually to face the birth process and prevent perineal rupture. This study aims to determine prenatal yoga's effect on the duration of the second stage of labor and the incidence of perineal tears at the Bumi Sehat Foundation Ubud Bali in 2018. The study was conducted by analytic design with a prospective study approach. The research subjects used 50 pregnant women who gave birth at the Bumi Sehat Foundation. The study used Mann-Whitney and chi-square. Based on the data analysis of the influence between Prenatal yoga on the duration of the second stage of analysis using Mann-Whitney p-value <0.005 which means that there is an influence between prenatal yoga on the second time while based on Chi-square data analysis p-value 0.012 where p-value <0, 005 which means that there is an influence between Prenatal yoga and perineum tear. It can be concluded that prenatal yoga is effective in helping pregnancy and childbirth are minimally traumatic in women.
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Daniyati, Asri, and Shohipatul Mawaddah. "Effect of Prenatal Yoga on Duration of the First Stage of Labor and Perineal Rupture in Primigravida Mothers." Research Journal of Life Science 8, no. 1 (April 1, 2021): 34–39. http://dx.doi.org/10.21776/ub.rjls.2021.008.01.5.
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In primigravidas, the first stage of labor has a longer duration than multiparous. The first stage of labor in primiparous is around 13-14 hours, while in multiparous it is about 7 hours. Prolonged labor is one of the causes of maternal death. Yoga in pregnancy can maintain elasticity and strength of the ligaments of the pelvis, hips, and leg muscles, so that it can reduce pain during labor and provide space for the birth canal. The comparative analytical research method used pre-experimental design with the one shot case study design. With a sample of 26 trimesters III primigravida pregnant women who were divided into 2 groups, namely n = 13 groups who did prenatal yoga, and n = 13 groups who did not do prenatal yoga. The analysis of this research was univariate and bivariate using the Mann Whitney test. Assessment is carried out during the delivery process. As a result, the intervention and control groups with active phase I labor duration obtained p = 0.000, and perineal rupture p = 0.000. There was a significant difference in the length of the first stage of labor and perineal rupture between the yoga group and the non-yoga group. Prenatal yoga affects the duration of the first stage of labor and perineal rupture.
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Shavaliev, R. F., Sabina Sh Yafarova, and S. Ya Volgina. "PREVENTION OF ORPHAN DISEASES: CONTEMPORARY ASPECTS AND NEW CHALLENGES." Russian Pediatric Journal 20, no. 4 (April 30, 2019): 226–32. http://dx.doi.org/10.18821/1560-9561-2017-20-4-226-232.
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The authors represent current data concerning the management of the prevention of orphan diseases. Determinations of modes and levels of the prevention have been formulated. The importance of pre-gravity care, medical genetic counseling, assisted reproductive technologies, methods of prenatal diagnosis and fetal surgery, neonatal screening at certain stages of the organization of preventive measures is reflected. Specific features of screening for rare diseases with the use of rapid diagnostics methods are described: a solid approach, mass character, preventive orientation and stage-by-stage approach. Topical issues of the prevention of orphan diseases are considered.
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Rumyantsev, A. G. "PRENATAL AND NEONATAL SCREENING OF NEWBORNS." Pediatria. Journal named after G.N. Speransky 102, no. 1 (February 17, 2023): 114–22. http://dx.doi.org/10.24110/0031-403x-2023-102-1-114-122.
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Thorough observation after childbirth and additional examination of newborns based on prenatal and neonatal screening, including the screening of blood, hearing, congenital heart defects and other organs and systems, and in case of indications for hereditary diseases - the genetic examination, does allow not only at the clinical, but also at the pre-clinical stage the planning of preventive and therapeutic measures for newborns and early-age children. This read offers a working algorithm for prenatal and neonatal screening of newborns.
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Lindgren, I., and J. Altimiras. "Prenatal hypoxia programs changes in β-adrenergic signaling and postnatal cardiac contractile dysfunction." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 305, no. 10 (November 15, 2013): R1093—R1101. http://dx.doi.org/10.1152/ajpregu.00320.2013.
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Prenatal hypoxia leads to an increased risk of adult cardiovascular disease. We have previously demonstrated a programming effect of prenatal hypoxia on the cardiac β-adrenergic (βAR) response. The aim of this study was to determine 1) whether the decrease in βAR sensitivity in prenatally hypoxic 5-wk old chicken hearts is linked to changes in β1AR/β2ARs, Gαi expression and cAMP accumulation and 2) whether prenatal hypoxia has an effect on heart function in vivo. We incubated eggs in normoxia (N, 21% O2) or hypoxia from day 0 (H, 14% O2) and raised the posthatchlings to 5 wk of age. Cardiac β1AR/β2ARs were assessed through competitive binding of [3H]CGP-12177 with specific β1AR or β2AR blockers. Gαs and Gαi proteins were assessed by Western blot and cAMP accumulation by ELISA. Echocardiograms were recorded in anesthetized birds to evaluate diastolic/systolic diameter and heart rate and tissue sections were stained for collagen. We found an increase in relative heart mass, β1ARs, and Gαs in prenatally hypoxic hearts. cAMP levels after isoproterenol stimulation and collagen content was not changed in H compared with N, but in vivo echocardiograms showed systolic contractile dysfunction. The changes in βAR and G protein subtypes may be indicative of an early compensatory stage in the progression of cardiac dysfunction, further supported by the cardiac hypertrophy and systolic contractile dysfunction. We suggest that it is not the changes in the proximal part of the βAR system that causes the decreased cardiac contractility, but Ca2+ handling mechanisms further downstream in the βAR signaling cascade.
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Dariyani, Siti, Reni Nofita, and Mardi Yana. "Pengembangan Media Self Trainning Basic Prenatal Yoga Berbasis Audiovisual di Puskesmas Pamulang Tangerang Selatan." Indonesian Journal of Midwifery (IJM) 4, no. 1 (March 31, 2021): 17. http://dx.doi.org/10.35473/ijm.v4i1.682.
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Pregnancy and childbirth are inseparable chain reactions in a normal woman's life. To undergo a safe and comfortable pregnancy, pregnant women must be able to manage their body, mind and spirit holistically during pregnancy. (Kuswandi,2013) Changes in the safety and comfort of pregnant women are closely related to physical and psychological changes. (Prawiroharjo,2015) To reduce the physical and psychological complaints of mothers during pregnancy, what can be done by including the mother in pregnancy exercise classes, Prenatal yoga is a type of exercise that is good for pregnant women to do. Practicing yoga means that pregnant women practice physical postures, breathing techniques, and meditation.Based on the data obtained at Pamulang Health Center, from 684 pregnant women during January to April, only 20% of pregnant women attended the pregnancy class provided by the puskesmas, the remaining 80% of pregnant women were not involved in gymnastics classes at all. The absence of pregnant women is due to busyness and unsuitable schedules. The general objective of this study is to develop audiovisual self-training media for basic prenatal yoga and to test its effectiveness.The research method is action research. The first stage will conduct a study of the condition and level of needs of pregnant women about basic prenatal yoga. The second stage will be the process of making audiovisual media for basic prenatal yoga self-training. The third stage is testing the effectiveness of the media. The results showed that 60% of respondents did not know well what Prenatal Yoga was, pre-intervention described the mean score of physiological comfort during pregnancy of 56.1 with a range of values ranging from a score of 35-77. The mean value obtained post intervention was 48.4 with scores ranging from 30-70. p value of 0,000. Thus, it is known that there is a significant relationship between prenatal yoga movements and physiological comfort during pregnancy.
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Fitriyah, Lailatul Fitri. "Prenatal Education In the Qur'an." Al Karima : Jurnal Studi Ilmu Al Quran dan Tafsir 7, no. 1 (March 18, 2023): 38. http://dx.doi.org/10.58438/js.v7i1.139.
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Prenatal education is very important education in child development, because prenatal education is foundation education for childrens. In the Al-Qur’an there is verse wich explain about prenatal education on of them is surah An-nahl verse 78 . In this research the writer reaserched surah an-nahl verse 78 according of the commentators of Al-Qur’an. In this research uses library reaserch and this reaserch method uses the Maudhu’I method. The purpose of this research is to knowing of explain the commentators of Al-Qur’an about prenatal education in the Qur’an Surah An-Nahl verse 78. The purpose of this research to know opinion of commentator of the Qur’an about prenatal education in the surah an-nahl verse 78. In this research the are some opinions commentator of the Qur’an, that is the first, the are commentator who think is prenatal education can occur at the stage of pregnance because senses are working and can receive stimulation from outside the womb, the second opinion, the are commentator who think is prenatal education can not happen because the senses can not working and can not receive stimulation from outside the womb, third opinion, does not link surah an-nahl verse 78 with prenatal education.
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Ponkin, I. V., A. A. Ponkina, and A. S. Shkoda. "A child’s right to receive pediatric palliative care at prenatal stage." Obstetrics, Gynecology and Reproduction 14, no. 1 (April 4, 2020): 80–88. http://dx.doi.org/10.17749/2313-7347.2020.14.1.80-88.
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Shiozaki, Kazunari, Kaori Fukami, Ami Kuribayashi, Shinji Shimoda, and Kaoru Kobayashi. "Mandibular lingual canals distribute to the dental crypts in prenatal stage." Surgical and Radiologic Anatomy 36, no. 5 (September 12, 2013): 447–53. http://dx.doi.org/10.1007/s00276-013-1201-6.
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Bonnet, C. J. "Prevention of neonaticide and abandonment from a prenatal stage in France." European Psychiatry 22 (March 2007): S70. http://dx.doi.org/10.1016/j.eurpsy.2007.01.269.
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Constantin, Stephanie, Ulrike Klenke, and Susan Wray. "The Calcium Oscillator of GnRH-1 Neurons Is Developmentally Regulated." Endocrinology 151, no. 8 (June 16, 2010): 3863–73. http://dx.doi.org/10.1210/en.2010-0118.
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Oscillations in intracellular calcium levels have been described in GnRH-1 neurons in both prenatal and adult cells. However, differences have been reported in the mechanisms underlying these [Ca2+]i oscillations, dependent on the model used. The goal of this study was to address whether these changes depend on the maturation status of GnRH-1 neurons by assaying prenatal GnRH-1 cells maintained in explants, at two different developmental stages. This report documents an increase in the frequency of [Ca2+]i oscillations between 1 and 3 wk of in vitro maturation. During the early stage, [Ca2+]i oscillations are blocked by tetrodotoxin and are mainly triggered by excitatory neurotransmitters, γ-aminobutyric acid (GABA), and glutamate. In contrast, in the later stage, some cells exhibit residual tetrodotoxin-insensitive [Ca2+]i oscillations, which are sustained by action potential-independent GABA and glutamate release. The strength of these two excitatory inputs remained relatively constant during the maturation process, and the increase in frequency of [Ca2+]i oscillations observed at the later stage is due to a novel excitatory input carried by cholecystokinin. Together, these data indicate developmentally regulated release and interactions of neurotransmitters (known regulators of GnRH-1 cells in adults) and point to extrinsic factors regulating GnRH-1 cellular physiology.
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Popova, I. "MORPHOLOGICAL FEATURES OF FASCIAL STRUCTURES IN INFRAHYOID NECK DURING PRENATAL HUMAN ONTOGENESIS." Clinical anatomy and operative surgery 19, no. 1 (February 27, 2020): 93–97. http://dx.doi.org/10.24061/1727-0847.19.1.2020.16.
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Fascia and fascial spaces of the neck remains a controversial morphological question, which requires in-depth study, especially in the focus of prenatal morphogenesis. We have examined specimens of human embryos, prefetuses and fetuses in order to study the development and topographic-anatomical features of the neck fascial structures at different stages of human prenatal development. For this purpose, a set of microscopic methods (three-dimensional reconstruction, series of histological sections examination) for embryos (8.0-13.0 mm PCL (parieto-coccygeal length) and prefetuses (14.0-80.0 mm PCL) was used; macroscopic examination for fetuses’ specimens (80.0-230.0 mm PCL). It was found that at the end of the embryonic period of development, there are rudiments of the larynx and pharynx, which are not delimited; precrusors of vascular and nerve trunks of the neck are already present. In the prefetal we may observe change from the bilaminar to multilaminar fascial morphology. The definitive structure of fascial structures may be found in fetal stage of human ontogenesis. It is important that at fetal stage, fascial leaves tend to fuse in areas that contact with the periosteum or in the fascial spaces that do not yet contain adipose tissue yet.
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Gottschalk, Ingo, Brigitte Strizek, Christel Jehle, Rüdiger Stressig, Ulrike Herberg, Johannes Breuer, Konrad Brockmeier, et al. "Prenatal Diagnosis and Postnatal Outcome of Fetuses with Pulmonary Atresia and Ventricular Septal Defect." Ultraschall in der Medizin - European Journal of Ultrasound 41, no. 05 (January 7, 2019): 514–25. http://dx.doi.org/10.1055/a-0770-2832.
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AbstractPurpose To assess the intrauterine course, associated conditions and postnatal outcome of fetuses with pulmonary atresia with ventricular septal defect (PAVSD).Methods All cases of PAVSD diagnosed prenatally over a period of 10 years with a minimum follow-up of 6.5 years were retrospectively collected in 3 tertiary referral centers.Results 50 cases of PAVSD were diagnosed prenatally. 44.0 % of fetuses had isolated PAVSD, 4.0 % had associated cardiac anomalies, 10.0 % had extra-cardiac anomalies, 38.0 % had chromosomal anomalies, 4.0 % had non-chromosomal syndromes. Among the 32 liveborn children, 56.3 % had reverse flow in the patent arterial duct, 25.0 % had major aortopulmonary collateral arteries (MAPCAs) with ductal agenesis and 18.7 % had a double supply. 17 pregnancies were terminated (34.0 %), there was 1 intrauterine fetal death (2.0 %), 1 neonatal death (2.0 %), and 6 deaths (12.0 %) in infancy. 25 of 30 (83.3 %) liveborn children with an intention to treat were alive at the latest follow-up. The mean follow-up among survivors was 10.0 years (range 6.5–15.1). 56.0 % of infants underwent staged repair, 44.0 % had one-stage complete repair. After exclusion of infants with additional chromosomal or syndromal anomalies, 88.9 % were healthy, and 11.1 % had mild limitations. The presence of MAPCAs did not differ significantly between survivors and non-survivors (p = 0.360), between one-stage or staged repair (p = 0.656) and healthy and impaired infants (p = 0.319).Conclusion The prognosis in cases without chromosomal or syndromal anomalies is good. MAPCAs did not influence prognosis or postoperative health. The incidence of repeat interventions due to recurrent stenoses is significantly higher after staged compared with single-stage repair.
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Kapoor, Amita, and Stephen G. Matthews. "Prenatal Stress Modifies Behavior and Hypothalamic-Pituitary-Adrenal Function in Female Guinea Pig Offspring: Effects of Timing of Prenatal Stress and Stage of Reproductive Cycle." Endocrinology 149, no. 12 (August 28, 2008): 6406–15. http://dx.doi.org/10.1210/en.2008-0347.
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Prenatal stress is associated with altered behavior and hypothalamic-pituitary-adrenal (HPA) axis function postnatally. Recent studies suggest that these outcomes are dependent on the timing of the prenatal stress. The majority of these studies have been carried out in male offspring. We hypothesized that a short period of prenatal stress would result in female offspring that exhibit differences in open-field behavior and HPA axis activity, but the outcome would depend on the timing of the prenatal stress and the stage of the reproductive cycle. Pregnant guinea pigs were exposed to a strobe light during the fetal brain growth spurt [gestational d 50–52 (PS50)] or during the period of rapid brain myelination [gestational d 60–62 (PS60)]. Open-field activity was assessed in juvenile and adult female offspring. HPA axis function was tested in adult offspring. All tests in adulthood were carried out during the estrous and luteal phases of the reproductive cycle to determine the effect of stage on HPA axis programming. Tissues were collected upon completion of the study for analysis by in situ hybridization. PS60 offspring exhibited decreased activity in an open field during the estrous phase of the reproductive cycle compared with control offspring. Both PS50 and PS60 offspring exhibited a lower salivary cortisol response to a stressor, only during the estrous phase. Consistent with the behavioral and endocrine data, PS60 females exhibited lower plasma estradiol levels, reduced ovary weight, and increased glucocorticoid receptor mRNA in the paraventricular nucleus. In conclusion, we have demonstrated that there are effects of prenatal stress on behavior and HPA axis functioning in female offspring but that the outcomes are dependent on the timing of the prenatal stress together with the status of the reproductive cycle.
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Valencia, Martina, Odra Santander, Eloísa Torres, Natali Zamora, Fernanda Muñoz, and Rodrigo Pascual. "Environmental enrichment reverses cerebellar impairments caused by prenatal exposure to a synthetic glucocorticoid." AIMS Neuroscience 9, no. 3 (2022): 320–44. http://dx.doi.org/10.3934/neuroscience.2022018.
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<abstract> <p>During prenatal life, exposure to synthetic glucocorticoids (SGCs) can alter normal foetal development, resulting in disease later in life. Previously, we have shown alterations in the dendritic cytoarchitecture of Purkinje cells in adolescent rat progeny prenatally exposed to glucocorticoids. However, the molecular mechanisms underlying these alterations remain unclear. A possible molecular candidate whose deregulation may underlie these changes is the glucocorticoid receptor (GR) and neurotrophin 3/ tropomyosin receptor kinase C, neurotrophic complex (NT-3/TrkC), which specifically modulates the development of the neuronal connections in the cerebellar vermis. To date, no evidence has shown that the cerebellar expression levels of this neurotrophic complex are affected by exposure to a synthetic glucocorticoid in utero. Therefore, the first objective of this investigation was to evaluate the expression of GR, NT-3 and TrkC in the cerebellar vermis using immunohistochemistry and western blot techniques by evaluating the progeny during the postnatal stage equivalent to adolescence (postnatal Day 52). Additionally, we evaluated anxiety-like behaviours in progeny using the elevated plus maze and the marble burying test. In addition, an environmental enrichment (EE) can increase the expression of some neurotrophins and has anxiolytic power. Therefore, we wanted to assess whether an EE reversed the long-term alterations induced by prenatal betamethasone exposure. The major findings of this study were as follows: i) prenatal betamethasone (BET) administration decreases GR, NT-3 and TrkC expression in the cerebellar vermis ii) prenatal BET administration decreases GR expression in the cerebellar hemispheres and iii) enhances the anxiety-like behaviours in the same progeny, and iv) exposure to an EE reverses the reduced expression of GR, NT-3 and TrkC in the cerebellar vermis and v) decreases anxiety-like behaviours. In conclusion, an enriched environment applied 18 days post-weaning was able to restabilize GR, NT-3 and TrkC expression levels and reverse anxious behaviours observed in adolescent rats prenatally exposed to betamethasone.</p> </abstract>
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Shahjahan, Md. "Skeletal muscle development in vertebrate animals." Asian Journal of Medical and Biological Research 1, no. 2 (November 23, 2015): 139–48. http://dx.doi.org/10.3329/ajmbr.v1i2.25592.
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This review covers the pre- and post-natal development of skeletal muscle of vertebrate animals with cellular and molecular levels. The formation of skeletal muscle initiates from paraxial mesoderm during embryogenesis of individuals which develops somites and subsequently forms dermomyotome derived myotome to give rise axial musculature. This process (myogenesis) includes stem and progenitor cell maintenance, lineage specification, and terminal differentiation to form myofibrils consequent muscle fibers which control muscle mass and its multiplication. The main factors of muscle growth are proliferation and differentiation of myogenic cells in prenatal stage and also the growth of satellite cells at postnatal stage. There is no net increase in the number of muscle fibers in vertebrate animals after hatch or birth except fish. The development of muscle is characterized by hyperplasia and hypertrophy in prenatal and postnatal stages of individuals, respectively, through Wnt signalling pathway including environment, nutrition, sex, feed, growth and myogenic regulatory factors. Therefore further studies could elucidate new growth related genes, markers and factors to enhance meat production and enrich knowledge on muscle growth.Asian J. Med. Biol. Res. June 2015, 1(2): 139-148
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Loginova, Julija Artemevna, and Olga Gavrilovna Chiryaeva. "Current state of preimplantation genetic diagnosis." Journal of obstetrics and women's diseases 61, no. 3 (May 15, 2012): 75–82. http://dx.doi.org/10.17816/jowd61375-82.
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Preimplantation genetic diagnosis was first reported 20 years ago. During this time the range of possibilities of assisted reproductive technology has expanded and the possibility of molecular diagnosis of single cells greatly increased. Preimplantation diagnosis has evolved from an experimental procedure to an efficient form of Prenatal Diagnosis, which broadened the indications for Prenatal Diagnosis and can be applied at the earliest stage. This review shows the current state of preimplantation genetic diagnosis and describes its capabilities
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Harvie, Sarah, Lynne McLeod, Philip Acott, Eilish Walsh, Mohamed Abdolell, and Marian B. Macken. "Abnormal Antenatal Sonogram: An Indicator of Disease Severity in Children with Posterior Urethral Valves." Canadian Association of Radiologists Journal 60, no. 4 (October 2009): 185–89. http://dx.doi.org/10.1016/j.carj.2009.06.003.
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Purpose To review the association of an abnormal prenatal sonogram with most recent serum creatinine in patients with proven posterior urethral valves (PUV). Methods Since 1992, all live-born patients between 1992–2004 with clinically proven PUV, with postnatally proven PUV, from 2 pediatric tertiary care centers, were reviewed for age at diagnosis, most recent serum creatinine, presence of chronic renal failure (CRF) (serum creatinine >2 standard deviations above normal for age), or end stage renal disease (dialysis or transplant). Available antenatal reports from the 2 centres and surrounding community hospitals were reviewed for gestational age (GA) at the time of ultrasound, volume of amniotic fluid, and urinary-tract abnormality. Results Thirty-four patients with proven PUV and prenatal sonograms were identified (1992–2004). Eighteen patients had abnormalities on their prenatal sonogram, with poor outcome in 5 (mean follow-up, 8 years [1–13 y]). No specific features were identified on prenatal sonogram. Sixteen patients had normal prenatal sonograms, with poor outcomes in 2 (mean follow-up, 8 years [3–13y]). There is an increased risk of an abnormal serum creatinine among those patients with an abnormal prenatal study, odds ratio (OR) 2.6 (95% confidence interval, 0.35–32). Conclusions PUV represents a spectrum of disease severity. A normal prenatal ultrasound does not preclude PUV. The majority of patients with a normal prenatal examination have good outcomes. The OR suggests that there may be increased risk for poor outcome in those with an abnormal prenatal examination. A multicenter study is necessary to obtain a larger sample size and more precise ORs.
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NAKAGAMI, Akiko, Takamasa KOYAMA, and Kastuyoshi KAWASAKI. "Did prenatal exposure of DPAA affect infant behaviors during early developmental stage?" Proceedings of the Annual Convention of the Japanese Psychological Association 74 (September 20, 2010): 2PM065. http://dx.doi.org/10.4992/pacjpa.74.0_2pm065.
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Yang, K. D., J. C. Chang, H. Chuang, H. M. Liang, H. C. Kuo, Y. S. Lee, T. Y. Hsu, and C. Y. Ou. "Gene-gene and gene-environment interactions on IgE production in prenatal stage." Allergy 65, no. 6 (November 25, 2009): 731–39. http://dx.doi.org/10.1111/j.1398-9995.2009.02260.x.
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Antonson, Adrienne M. "“Prenatal programming of the brain: The maternal-fetal interface takes center stage”." Brain, Behavior, and Immunity 109 (March 2023): 219–20. http://dx.doi.org/10.1016/j.bbi.2023.01.019.
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Sharma, Pushpa, and Anil Sharma. "Collection and Analysis of Patients Dataset to Develop an E Health System for the Prediction of Inherited Prenatal Disorders." Journal of Computational and Theoretical Nanoscience 16, no. 12 (December 1, 2019): 5118–21. http://dx.doi.org/10.1166/jctn.2019.8572.
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Electronic healthcare systems are continuously used by healthcare professionals for caring and providing health services to remote patients. In current scenario, variety of e-Health systems have been made to provide healthcare services such as medical consultancy, hospital-record organization and training–learning to distant public. But very few systems have been identified in context of prenatal care and inherited prenatal disorder, more specifically in case of haematological disorders. Hence, the authors opted the gap and proposed the development of an e-Health system which will predict the chances of inheriting haematological disorders from parents to offspring during preconception/prenatal stage. For this, authors collected and analyzed the pathological data set of few patients suffering from haematological disorders; which is presented in this paper.
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Koh, Ji Hye, Hyo Jeong Lee, Jinyoung Choi, and Jun Woo Ahn. "Prenatal Diagnosis of Right-Sided Congenital Ventricular Diverticulum (CVD) Assisted by Spatiotemporal Image Correlation (STIC) Acquisition and the Speckle-Tracking Technique to Assess Fetal Cardiac Function: A Case Report." Diagnostics 12, no. 10 (October 8, 2022): 2438. http://dx.doi.org/10.3390/diagnostics12102438.
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Congenital ventricular diverticulum (CVD) is a cardiac malformation defined as an outpouching lesion of a ventricle with normal contractility and thickness, and the advancement of prenatal sonography has led to its prenatal diagnosis. In the prenatal period, CVD is reported in association with pericardial effusion, arrhythmia, and fetal hydrops or as an isolated condition. With the development of prenatal echocardiography, CVD can be diagnosed from the early stage of pregnancy, and prenatal procedures, such as pericardiocentesis, are also possible. Spatiotemporal image correlation (STIC) acquisition, a novel approach for the clinical evaluation of fetal hearts, provides easy-to-use techniques for acquiring data from fetal hearts and helping visualization with two-dimensional and three-dimensional (3D) cine sequences. Furthermore, the speckle-tracking technique enables a more comprehensive evaluation of the shape, continuity, and function of the fetal heart. These recent techniques have never been used for CVD diagnosis and evaluation. Here, we present a case of right-sided CVD, which is the first in which STIC acquisition and cardiac function assessment with the speckle-tracking technique were used to assist in the diagnosis and evaluation.
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Santos, Luzia Aparecida dos, Fabiana Villela Mamede, Maria José Clapis, and Juliana Villela Bueno Bernardi. "Nutritional guidance during prenatal care in public health services in Ribeirão Preto: discourse and care practice." Revista Latino-Americana de Enfermagem 14, no. 5 (October 2006): 688–94. http://dx.doi.org/10.1590/s0104-11692006000500008.
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This study aimed to verify if pregnant women attended in prenatal care services at Basic Health Units in Ribeirão Preto-SP, Brazil, received nutritional guidance and if this guidance was pertinent to their nutritional status. Ninety-one pregnant women participated. The pregnant women were classified according to their nutritional condition, using a weight, height and pregnancy stage table established by the Brazilian Health Ministry's technical prenatal care manual. We found pregnant women with weight under (13.19%) and exceeding normal levels (37.36%). Independently of their nutritional condition, most of them (60.43%) declared they did not receive nutrition guidance. The mean number of prenatal visits did not influence the nutritional status. The results reveal deficiencies in the contents and quality of nutritional care. This suggests the need for care changes so as to turn discourse into practice.
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Huang, Yifang, Sheng Yu, Shuzhe Chao, Limei Wu, Maliang Tao, Bo Situ, Xinyi Ye, et al. "Isolation of circulating fetal trophoblasts by a four-stage inertial microfluidic device for single-cell analysis and noninvasive prenatal testing." Lab on a Chip 20, no. 23 (2020): 4342–48. http://dx.doi.org/10.1039/d0lc00895h.
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A novel four-stage inertial microfluidic chip is developed for isolating rare circulating trophoblastic cells from whole blood samples of pregnancies. The antibody-free, low-cost assay may serve as a useful platform for noninvasive prenatal testing.
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Maharani, Hervina Wilhelmina, Siti Nurhidayati, Niken Bayu Argaheni, Luluk Fajria Maulida, and Ika Sumiyarsi Sukamto. "The correlation between the intensity of prenatal yoga participation on anxiety levels for third trimester pregnant women in facing childbirth in Kartasura district." Journal of Health Technology Assessment in Midwifery 5, no. 2 (December 19, 2022): 123–29. http://dx.doi.org/10.31101/jhtam.2689.
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Background:Data from the World Health Organization (WHO) show that pregnant women experience anxiety by 8-10% during pregnancy, and it increases to 13% when they are about to give birth. The incidence of anxiety in pregnant women in Indonesia reaches 373,000, 28.7% of which anxiety occurs in pregnant women when facing childbirth. Sustained anxiety will increase the likelihood of cesarean section, prolonged second stage, asphyxia and affect fetal neurodevelopment and fetal cognitive. One of the physical exercises that can reduce anxiety is prenatal yoga. The purpose of this study was to determine the relationship between the intensity of prenatal yoga participation on the level of anxiety of pregnant women in the third trimester in facing childbirth in Kartasura District.Methods: Cross-sectional study design. The population in this study were all third trimester pregnant women who did prenatal yoga and did prenatal checkups at midwife Wulan, Anik Midwife Health House and Auliya Husada Clinic with a total population of 42 people. The sample of this study used accidental sampling and total sampling. The research instrument used the Perinatal Anxiety Screening Scale (PASS), and used univariate and bivariate data analysis with the Spearman test.Results: A total of 22 pregnant women who did not participate in prenatal yoga experienced severe anxiety by 54.6% (12 people), while of the 20 pregnant women who participated in prenatal yoga, most experienced mild anxiety by 50% (10 people). Based on statistical tests using the Spearman test, p-value 0.05 was obtained.Conclusion: There is a relationship between the intensity of prenatal yoga participation on the level of anxiety of pregnant women in the third trimester in facing childbirth in Kartasura District.Suggestion: It is hoped that pregnant women who have not followed prenatal yoga regularly participate in prenatal yoga in order to reduce discomfort and anxiety.
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Jackson, Leslie M., Andrea Mytinger, Eila K. Roberts, Theresa M. Lee, Douglas L. Foster, Vasantha Padmanabhan, and Heiko T. Jansen. "Developmental Programming: Postnatal Steroids Complete Prenatal Steroid Actions to Differentially Organize the GnRH Surge Mechanism and Reproductive Behavior in Female Sheep." Endocrinology 154, no. 4 (April 1, 2013): 1612–23. http://dx.doi.org/10.1210/en.2012-1613.
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Abstract In female sheep, estradiol (E2) stimulates the preovulatory GnRH/LH surge and receptive behavior, whereas progesterone blocks these effects. Prenatal exposure to testosterone disrupts both the positive feedback action of E2 and sexual behavior although the mechanisms remain unknown. The current study tested the hypothesis that both prenatal and postnatal steroids are required to organize the surge and sex differences in reproductive behavior. Our approach was to characterize the LH surge and mating behavior in prenatally untreated (Control) and testosterone-treated (T) female sheep subsequently exposed to one of three postnatal steroid manipulations: endogenous E2, excess E2 from a chronic implant, or no E2 due to neonatal ovariectomy (OVX). All females were then perfused at the time of the expected surge and brains processed for estrogen receptor and Fos immunoreactivity. None of the T females exposed postnatally to E2 exhibited an E2-induced LH surge, but a surge was produced in five of six T/OVX and all Control females. No surges were produced when progesterone was administered concomitantly with E2. All Control females were mounted by males, but significantly fewer T females were mounted by a male, including the T/OVX females that exhibited LH surges. The percentage of estrogen receptor neurons containing Fos was significantly influenced in a brain region-, developmental stage-, and steroid-specific fashion by testosterone and E2 treatments. These findings support the hypothesis that the feedback controls of the GnRH surge are sensitive to programming by prenatal and postnatal steroids in a precocial species.
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Guo, Jiazhong, Wei Zhao, Siyuan Zhan, Li Li, Tao Zhong, Linjie Wang, Yao Dong, and Hongping Zhang. "Identification and Expression Profiling of miRNAome in Goat longissimus dorsi Muscle from Prenatal Stages to a Neonatal Stage." PLOS ONE 11, no. 10 (October 31, 2016): e0165764. http://dx.doi.org/10.1371/journal.pone.0165764.
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Unwin, David Michael, and D. Charles Deeming. "Prenatal development in pterosaurs and its implications for their postnatal locomotory ability." Proceedings of the Royal Society B: Biological Sciences 286, no. 1904 (June 12, 2019): 20190409. http://dx.doi.org/10.1098/rspb.2019.0409.
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Recent fossil finds in China and Argentina have provided startling new insights into the reproductive biology and embryology of pterosaurs, Mesozoic flying reptiles. Nineteen embryos distributed among four species representing three distinct clades have been described and all are assumed to be at, or near, term. We show here how the application of four contrasting quantitative approaches allows a more precise identification of the developmental status of embryos revealing, for the first time to our knowledge, the presence of middle and late developmental stages as well as individuals that were at term. We also identify a predicted relationship between egg size and shape and the developmental stage of embryos contained within. Small elongate eggs contain embryos at an earlier stage of development than larger rounder eggs which contain more fully developed embryos. Changes in egg shape and size probably reflect the uptake of water, consistent with a pliable shell reported for several pterosaurs. Early ossification of the vertebral column, limb girdles and principal limb bones involved some heterochronic shifts in appearance times, most notably of manus digit IV, and facilitated full development of the flight apparatus prior to hatching. This is consistent with a super-precocial flight ability and, while not excluding the possibility of parental care in pterosaurs, suggests that it was not an absolute requirement.
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Gu, Weikuan. "Healthy Long-Lived Human Beings—Working on Life Stages to Break the Limitation of Human Lifespans." Biology 11, no. 5 (April 24, 2022): 656. http://dx.doi.org/10.3390/biology11050656.
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The human lifespan has been increasing but will soon reach a plateau. A new direction based on the principal law of lifespan (PLOSP) may enable the human lifespan to be extremely healthy and long by the proper manipulation of the well-defined growing stages of the lifespan. The lifespan of creatures on earth from a single cell to animals can be elongated at different life stages including prenatal development, body growth, reproductivity, and aging. Each life stage has its own specific physiological and metabolic characteristics. Each life stage can be lengthened by either slowing its processes or continuously maintaining the activities of its function. Unfortunately, the current biomedical research on the extension of lifespans has mainly focused on the aging stage. Recognizing and clearly defining the periods of transition and the boundaries of life stages are essential for achieving the goal of long-lived healthy humans based on the PLOSP. The biomedical measures and pharmacological treatments for the extension of lifespans is life-stage-specific. The PLOSP can be tested with modified studies on longevity with a variety of technologies such as castration and ovariectomy. Sex differences in biological functions and the sequential order of the life stages requires different approaches for females and males.
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Gu, Weikuan. "Healthy Long-Lived Human Beings—Working on Life Stages to Break the Limitation of Human Lifespans." Biology 11, no. 5 (April 24, 2022): 656. http://dx.doi.org/10.3390/biology11050656.
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The human lifespan has been increasing but will soon reach a plateau. A new direction based on the principal law of lifespan (PLOSP) may enable the human lifespan to be extremely healthy and long by the proper manipulation of the well-defined growing stages of the lifespan. The lifespan of creatures on earth from a single cell to animals can be elongated at different life stages including prenatal development, body growth, reproductivity, and aging. Each life stage has its own specific physiological and metabolic characteristics. Each life stage can be lengthened by either slowing its processes or continuously maintaining the activities of its function. Unfortunately, the current biomedical research on the extension of lifespans has mainly focused on the aging stage. Recognizing and clearly defining the periods of transition and the boundaries of life stages are essential for achieving the goal of long-lived healthy humans based on the PLOSP. The biomedical measures and pharmacological treatments for the extension of lifespans is life-stage-specific. The PLOSP can be tested with modified studies on longevity with a variety of technologies such as castration and ovariectomy. Sex differences in biological functions and the sequential order of the life stages requires different approaches for females and males.
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Hui, Lisa, Alice Poulton, Eliza Kluckow, Anthea Lindquist, Briohny Hutchinson, Mark D. Pertile, Leonard Bonacquisto, et al. "A minimum estimate of the prevalence of 22q11 deletion syndrome and other chromosome abnormalities in a combined prenatal and postnatal cohort." Human Reproduction 35, no. 3 (March 2020): 694–704. http://dx.doi.org/10.1093/humrep/dez286.
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Abstract STUDY QUESTION What is the frequency of major chromosome abnormalities in a population-based diagnostic data set of genomic tests performed on miscarriage, fetal and infant samples in a state with >73 000 annual births? SUMMARY ANSWER The overall frequency of major chromosome abnormalities in the entire cohort was 28.2% (2493/8826), with a significant decrease in the detection of major chromosome abnormalities with later developmental stage, from 50.9% to 21.3% to 15.6% of tests in the miscarriage, prenatal and postnatal cohorts, respectively. WHAT IS KNOWN ALREADY Over the past decade, technological advances have revolutionized genomic testing at every stage of reproduction. Chromosomal microarrays (CMAs) are now the gold standard of chromosome assessment in prenatal diagnosis and pediatrics. STUDY DESIGN, SIZE, DURATION A population-based cohort study including all chromosome analysis was performed in the Australian state of Victoria during a 24-month period from January 2015 to December 2016. All samples obtained via invasive prenatal diagnosis and postnatal samples from pregnancy tissue and infants ≤12 months of age were included. PARTICIPANTS/MATERIALS, SETTING, METHODS A research collaboration of screening and diagnostic units in the Australian state of Victoria was formed (the Perinatal Record Linkage collaboration), capturing all instances of prenatal and postnatal chromosome testing performed in the state. Victoria has over 73 000 births per annum and a median maternal age of 31.5 years. We analyzed our population-based diagnostic data set for (i) chromosome assessment of miscarriage, prenatal diagnosis and postnatal samples; (ii) testing indications and diagnostic yields for each of these cohorts; (iii) and the combined prenatal/infant prevalence of 22q11.2 deletion syndrome (DS) as a proportion of all births ≥20 weeks gestation. MAIN RESULTS AND THE ROLE OF CHANCE During the 24-month study period, a total of 8826 chromosomal analyses were performed on prenatal and postnatal specimens in Victoria. The vast majority (91.2%) of all chromosome analyses were performed with CMA. The overall frequency of major chromosome abnormalities in the entire cohort was 28.2% (2493/8826). There was a significant decreasing trend in the percentage of chromosome abnormalities with later developmental stage from 50.9% to 21.3% to 15.6% in the miscarriage, prenatal and postnatal cohorts, respectively (χ2 trend = 790.0, P < 0.0001). The total frequency of abnormalities in the live infant subgroup was 13.4% (244/1816). The frequencies of pathogenic copy number variants (CNVs) detected via CMA for the miscarriage, prenatal and postnatal cohorts were 1.9% (50/2573), 2.2% (82/3661) and 4.9% (127/2592), respectively. There was a significant increasing trend in the frequency of pathogenic CNVs with later developmental stage (χ2 trend = 39.72, P < 0.0001). For the subgroup of live infants, the pathogenic CNV frequency on CMA analysis was 6.0% (109/1816). There were 38 diagnoses of 22q11.2 DS, including 1 miscarriage, 15 prenatal and 22 postnatal cases. After excluding the miscarriage case and accounting for duplicate testing, the estimated prevalence of 22q11 DS was 1 in 4558 Victorian births. LIMITATIONS, REASONS FOR CAUTION Clinical information was missing on 11.6% of postnatal samples, and gestational age was rarely provided on the miscarriage specimens. We were unable to obtain rates of termination of pregnancy and stillbirth in our cohort due to incomplete data provided by clinical referrers. We therefore cannot make conclusions on pregnancy or infant outcome following diagnostic testing. Childhood and adult diagnoses of 22q11 DS were not collected. WIDER IMPLICATIONS OF THE FINDINGS Our study marks a complete transition in genomic testing from the G-banded karyotype era, with CMA now established as the first line investigation for pregnancy losses, fetal diagnosis and newborn/infant assessment in a high-income setting. Integration of prenatal and postnatal diagnostic data sets provides important opportunities for estimating the prevalence of clinically important congenital syndromes, such as 22q11 DS. STUDY FUNDING/COMPETING INTEREST(S) L.H. is funded by a National Health and Medical Research Council Early Career Fellowship (1105603); A.L. was funded by a Mercy Perinatal Research Fellowship; J.H. was funded by a National Health and Medical Research Council Senior Research Fellowship (10121252). The funding bodies had no role in the conduct of the research or the manuscript. Discretionary funding from the Murdoch Children’s Research Institute has supported the prenatal diagnosis data collection and reporting over the years. Dr Ricardo Palma-Dias reports a commercial relationship with Roche Diagnostics, personal fees from Philips Ultrasound, outside the submitted work. Debbie Nisbet reports a commercial relationship with Roche Diagnostics, outside the submitted work. TRIAL REGISTRATION NUMBER NA