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Journal articles on the topic 'Prematurity'

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Author: Grafiati

Published: 4 June 2021

Last updated: 17 October 2023

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1

Kuznetsova, Yulia Dmytriеvna, L. M. Balashova, and S. N. Bykovskaya. "INVESTIGATION OF T-REGULATORY CELLS IN PREMATURY INFANTS." Russian Pediatric Ophthalmology 13, no. 1 (March 15, 2018): 46–53. http://dx.doi.org/10.18821/1993-1859-2018-13-1-46-53.

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Violation of the regulation of congenital immune reactions plays an important role in the etiology of common and serious neonatal complications in prematurely born children such as bronchopulmonary dysplasia, necrotizing enterocolitis, retinopathy of prematurity and others. This review is devoted to the study of one of the indicators of cellular immunity - T-regulatory cells CD4 + CD25 + FoxP3 + CD127low in prematury infants. Further studies of immunity and in particular T-regulatory cells in premature infants in various diseases, including retinopathy of prematurity, will further develop pathogenetically substantiated correction of immunological disorders to prevent their occurrence and progression.

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2

Tanto, Stefany, Gilbert Sterling Octavius, and Alvita Suci Edgina. "Effects of Adjuvant Administration of Macromolecules and Total Calories through Aggressive Parenteral Nutrition in Improvement of Neovascularisation of Infants with Retinopathy of Prematurity: A Literature Review." SCRIPTA SCORE Scientific Medical Journal 3, no. 2 (February 28, 2022): 138–50. http://dx.doi.org/10.32734/scripta.v3i2.4471.

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Introduction: Retinopathy of Prematurity (ROP) is almost exclusively in premature infants. With advanced care and technology, the prevalence of retinopathy of prematurity in babies is increasing, which means the incidence of preventable blindness in ROP is increasing. Objectives: To evaluate the effects of protein, glucose, lipids, and total calories from Aggressive Parenteral Nutrition (APN) in improving neovascularisation of ROP in premature infants. Methods: We searched PubMed, Ophthalmology Advance, Scientific Reports, and Science Direct using the terms "Retinopathy of Prematurity", "Aggressive Parenteral Nutrition", "Prevalence of Retinopathy of Prematurity in Indonesia", "Protein", "Lipid", "Carbohydrate", "Glucose", "Total Calories", "Neovascularization", and "Prematurity" in various combinations. Results: We found three pieces of literature stating a positive association between APN and improvement of ROP, while one literature states that there is no significant change of prevalence of ROP by administering APN. Keywords: Aggressive Parenteral Nutrition, glucose, lipid, protein, Retinopathy of Prematurity Pendahuluan: Retinopathy of Prematurity (ROP) adalah penyakit yang hampir secara eksklusif terjadi pada bayi prematur. Dengan perawatan dan teknologi yang canggih, prevalensi retinopati pada bayi prematur meningkat dan ini berarti kejadian kebutaan yang dapat dicegah pada ROP meningkat. Tujuan: Untuk mengevaluasi efek protein, glukosa, lipid, dan kalori total dari Nutrisi Parenteral Agresif (APN) dalam meningkatkan neovaskularisasi ROP pada bayi prematur. Metode: Kami mencari PubMed, Ophthalmology Advance, Scientific Reports dan Science Direct menggunakan istilah “Retinopathy of Prematurity”, “Aggressive Parenteral Nutrition”, “Prevalence of Retinopathy of Prematurity in Indonesia”, “Protein”, “Lipid”, “Carbohydrate” , "Glukosa", "Kalori Total", "Neovaskularisasi", dan "Prematuritas" dalam berbagai kombinasi. Hasil: Ditemukan tiga literatur yang menyatakan terdapat hubungan positif antara APN dengan peningkatan ROP sedangkan satu literatur menyatakan tidak ada perubahan signifikan prevalensi ROP dengan pemberian APN. Kata Kunci: Nutrisi Parenteral Agresif, glukosa, lipid, protein, Retinopati Prematuritas

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3

Birkun, E. Yu, S. A. Sorokina, T. A. Berezovskaya, and E. I. Saidasheva. "ORGANIZATION OF OPHTHALMOLOGICAL CARE FOR THE CHILDREN PRESENTING WITH RETINOPATHY OF PREMATURITY IN THE REPUBLIC OF CRIMEA." Russian Pediatric Ophthalmology 12, no. 4 (December 15, 2017): 216–18. http://dx.doi.org/10.18821/1993-1859-2017-12-4-216-218.

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Aim. The objective of the present study was to identify the main stages of the organization and the results of the ophthalmological care for the children presenting with retinopathy of prematurity (ROP) in the Republic of Crimea. Material and methods. This retrospective analysis of the results of ophthalmological screening of 2105 prematurely born children, monitoring of 281 children with the early stages of ROP, the laser-assisted treatment of 64 babies undergoing the progression of the disease to its threshold stages and the follow up of the children with ROP in the Crimea during the period from 1999 to 2016 years. All the above patients were nursed and treated in the clinical hospital over the territory of the Crimea and in the perinatal centre of Simferopol. Results. ROP was diagnosed in 281 (26%) of the 2105 prematurely born children. The progression of the disease to the threshold stage was documented in 64 (22.8%) patients within 1 to 12 (mean 3-4) weeks after the identification of the initial stages of active ROP. ROP of the posterior aggressive type developed in 15 children. The duly-timed laser-assisted treatment permitted to prevent the appearance of blindness among the prematurely born children attributable to retinopathy of prematurity. As a results of the implementation of the program for the modernization of the ophthalmological care for the retinopathy of prematurity in the Republic of Crimea it is currently organized and provided in conformity with the relevant normative acts of the Ministry of Health of the Russian Federation. The ophthalmological Department of the Republic of Crimea Children’s Clinical Hospital is equipped with the necessary modern medical and diagnostic instruments and techniques; training of the Crimean ophthalmologists in retinopathy of prematurity and laser-assisted treatment of active retinopathy of prematurity.

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Krivitskaya, L. V. "НЕДОНОШЕННЫЕ ДЕТИ: ФАКТОРЫ РИСКА, ОТДАЛЕННЫЕ ПОСЛЕДСТВИЯ." Health and Ecology Issues, no. 2 (June 28, 2018): 15–19. http://dx.doi.org/10.51523/2708-6011.2018-15-2-3.

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In recent years there is an increasing topicality of the problem of prematurity because of the growing incidence of premature births in spite of the treatment of pregnant women and application of modern technologies of pregnancy prolongation. According to the WHO report (2015), 15 million children are born prematurely every year and this number is increasing. The article analyzes the risk factors for miscarriage depending on the degree of prematurity and also studies the pathology of the perinatal period, physical and psychomotor development in the first year of life of premature infants. Some distant outcomes of prematurity related to disturbances of physical development, motor and neurological disorders, and premature infant`s intellectual malfunction have been analyzed.

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5

Costanzo, Caitlyn M., Charles Vinocur, and Loren Berman. "Prematurity Affects Age of Presentation of Pyloric Stenosis." Clinical Pediatrics 56, no. 2 (July 20, 2016): 127–31. http://dx.doi.org/10.1177/0009922816641367.

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Term infants with hypertrophic pyloric stenosis (HPS) typically present between 4 and 6 weeks. There is limited consensus, however, regarding age of presentation of premature infants. We aim to determine if there is an association between the degree of prematurity and chronological age of presentation of HPS. A total of 2988 infants who had undergone a pyloromyotomy for HPS were identified from the 2012 and 2013 NSQIP-P Participant Use Files. Two hundred seventeen infants (7.3%) were born prematurely. A greater degree of prematurity was associated with an older chronological age of presentation ( P < .0001). Prematurity was significantly associated with an increase in overall postoperative morbidity, reintubation, readmission, and postoperative length of stay. When clinicians evaluate an infant with nonbilious emesis with a history of prematurity, they should consider pyloric stenosis if the calculated postconceptional age is between 44 and 50 weeks. When counseling families of premature infants, surgeons should discuss the increased incidence of postpyloromyotomy morbidity.

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6

Yahya, Willy. "Retinopati Prematuritas : Diagnosis dan Tatalaksana." Cermin Dunia Kedokteran 47, no. 10 (October 1, 2020): 676. http://dx.doi.org/10.55175/cdk.v47i10.1080.

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<p>Retinopati prematuritas (ROP) adalah kelainan proliferatif progresif pembuluh darah retina bayi prematur yang dapat menyebabkan kebutaan. International Classification of Retinopathy of Prematurity (ICROP) membagi ROP berdasarkan tingkat keparahan, perluasan, lokasi, adanya penyakit lain, dan adanya ROP posterior yang agresif. ROP dimulai dari penundaan vaskularisasi retina akibat keadaan hiperoksia relatif dan dilanjutkan dengan fase vasoproliferasi. Skrining adekuat dengan oftalmoskop indirek dan tatalaksana sesuai pedoman The Early Treatment for Retinopathy of Prematurity (ETROP) menjadi modalitas penanganan ROP saat ini. Tatalaksana dengan modalitas lain masih diteliti.</p><p>Retinopathy of prematurity (ROP) is a proliferative, progressive vascularization in premature infants which can lead to blindness. International Classification of Retinopathy of Prematurity (ICROP) classified the ROP based on severity, extent, zone, the existence of other diseases, and the existence of aggressive posterior ROP. ROP starts with the delay of retinal vascularization from relative hyperoxia state and develops to vasoproliferation phase. Adequate screening by indirect ophthalmoscope and The Early Treatment for Retinopathy of Prematurity (ETROP) treatment guideline become the current modality for ROP therapy. Treatment with other modalities are still under investigation.</p>

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7

Popova, N. V., A. P. Goydin, and O. L. Fabrikantov. "Retinopathy of Prematurity. Review." Ophthalmology in Russia 18, no. 3 (October 1, 2021): 399–407. http://dx.doi.org/10.18008/1816-5095-2021-3-399-407.

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Retinopathy of prematurity (RP) is a complex pathology among prematurely born children, which requires a comprehensive approach, including both prevention of the development of more severe stages of the disease, leading to poor vision and irreversible loss of visual functions, and the organization of dispensary observation and rehabilitation. Modern organization of dispensary observation, which is based on a detailed study of the etiology, pathogenesis, as well as the interaction of local and systemic factors on visual functions, can significantly reduce the visual disability of children as a result of this disease.

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Tataj-Puzyna, Urszula, Karolina Kondraciuk, and Joanna Gotlib. "Selected problems of prematurity and prematurely born child care." Kwartalnik Naukowy Fides et Ratio 47, no. 3 (September 30, 2021): 23–42. http://dx.doi.org/10.34766/fetr.v47i3.795.

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The evolution of perinatology and the progress of advanced methods of prenatal diagnosis have contributed to the rise of frequency of birth and survival of newborns with very low birth weight, born before 32 weeks of pregnancy. A three-tier perinatology care system in Poland, an increasingly outstanding knowledge of neonatologists, and newer and more advanced equipment for critical care therapy, all provide growingly safer conditions for the life and development of prematurely born children. Prematurity is not only a problem of the preterm baby, but poses a challenge for the family, notably the mother, who must face the challenges of care of the preterm baby. In this article, selected problems of prematurity and care of a preterm baby are presented. The most common causes of preterm birth incidence are reported. The mother’s situation after a preterm birth is defined. Based on the current literature, the profile of preterm babies and the EBM (Evidence-Based Medicine) paradigm, the rules for treatment and care for a preterm baby are presented.

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Petrova, N. I., A. Y. Rascheskov, L. P. Bolgova, and N. M. Habibullina. "Effectiveness of 0.02% pentahydroxyethylnaphtoquinone (hystochrome) in patients with active and fibrous stages of retinopathy of prematurity." Kazan medical journal 93, no. 6 (December 15, 2012): 978–81. http://dx.doi.org/10.17816/kmj2124.

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Aim. To study the effectiveness and safety of pentahydroxyethylnaphtoquinone (Hystochrome) in patients with active and fibrous stages of retinopathy of prematurity. Methods. 281 prematurely born babies: first group - 63 patients with retinopathy of prematurity stages I-II and vast non-vascular area; second group - 201 baby with stage III retinopathy of prematurity and posterior aggressive form of retinopathy after the performed retinal laser photocoagulation; third group - 17 babies with subtotal intraocular hemorrhage - were followed up. In addition, 29 children with fibrous stage of retinopathy of prematurity were observed. Pentahydroxyethylnaphtoquinone (Hystochrome) was used as epibulbar instillations and peribulbar injections. To assess the treatment results, examination using the «RETCAM-120» system, B-scan ultrasonography using the «AVISO» scanner and visual evoked potentials examination with flash light stimulus using the «Neuro-MVP» device were performed. Results. In babies from the first group the improvement of electrophysiological parameters was observed in 20% of cases after treatment with pentahydroxyethylnaphtoquinone, compared to 4% in control group. In the second group pentahydroxyethylnaphtoquinone improved the electrophysiological parameters in 39% of cases. In the third group (17 babies with subtotal intraocular hemorrhage) the hemorrhage degradation was twice more rapid compared to controls. There was no effect from pentahydroxyethylnaphtoquinone treatment at the late stages of the disease. No adverse effects were registered. Conclusion. Pentahydroxyethylnaphtoquinone (Hystochrome) has shown good effectiveness and safety while treating patients with non-proliferative stages of retinopathy of prematurity and vitreous hemorrhage.

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10

Quinn, Graham E., and Velma Dobson. "Outcome of prematurity and retinopathy of prematurity." Current Opinion in Ophthalmology 7, no. 3 (June 1996): 51–56. http://dx.doi.org/10.1097/00055735-199606000-00009.

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11

Montvilaitė, Donata, Agnė Grizickaitė, Aistė Augytė, Inesa Skvarciany, Arūnas Barkus, and Vytautas Usonis. "Ophthalmological follow-up of prematurely born children in preschool age: prospective study of visual acuity, refractive errors and strabismus." Acta medica Lituanica 22, no. 4 (January 31, 2016): 205–15. http://dx.doi.org/10.6001/actamedica.v22i4.3239.

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Background. Preterm birth is a very relevant problem. Retinopathy of prematurity in its severe forms causes visual impairment or can lead to blindness. The aim of the present study was to describe the visual outcome in prematurely born and full-term children at the preschool age and to evaluate the effects of prematurity per se, ROP, and treatment on visual acuity and refractive errors. Materials and methods. A prospective study on the incidence of ROP during 2006–2008 included 103 preterm infants. 81 had ROP and 22 had no history of ROP; 40 were age-matched healthy children. All underwent a complete ophthalmic examination. Results. Significant myopia (≤ –0.50D) in prematurely born children differed from full-term ones. The ROP treated group had the highest prevalence of myopia (P 2D) was dominant in the premature group (39%) as compared with the control group (0%) (P

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12

Galán-Megías, Rocío, María Dolores Lanzarote-Fernández, Javier Casanovas-Lax, and Eva María Padilla-Muñoz. "Interaction of Impulsivity, Attention, and Intelligence in Early Adolescents Born Preterm without Sequelae." International Journal of Environmental Research and Public Health 18, no. 17 (August 27, 2021): 9043. http://dx.doi.org/10.3390/ijerph18179043.

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There is insufficient evidence on the intellectual and attentional profile of adolescents born prematurely. Aim: to identify maladjustment in intellectual and attention skills at the beginning of secondary school. Method: 69 premature 12-year-old adolescents were evaluated with the WISC, d2 Test of Attention, and Test of Perception of Differences-Revised (CARAS-R). Results: adolescents present intellectual and attention abilities in the normal range. However, all premature adolescents show difficulties in impulse control and female adolescents are better in processing speed. Depending on the category of prematurity, differences in attention skills are evident. Conclusion: adolescents born prematurely without associated sequelae have significantly lower performance in the same areas than the normative group. This could affect the cognitive control of their behavior and academic performance in the medium and long term. Great prematurity could interfere with attention skills and self-control even at the age of 12, especially in males.

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13

Tanjung, Wiwi Wardani, and Ayu Ulfah Nur Lubis. "HUBUNGAN PENGETAHUAN DAN RIWAYAT PENYAKIT DENGAN KELAHIRAN PREMATUR DI RUMAH SAKIT UMUM DAERAH KOTA PADANGSIDIMPUAN." JIDAN (JURNAL ILMIAH KEBIDANAN) 1, no. 2 (August 25, 2021): 72–76. http://dx.doi.org/10.51771/jdn.v1i2.90.

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The World Health Organization (WHO) reports that every year 13 million babies are born prematurely worldwide and one million babies die. The results of the 2013 Basic Health Research (Riskesdas) showed that 32.4% of infant deaths aged 0-6 days were caused by prematurity. Premature incidence in Padangsidimpuan City Hospital continues to increase from 2011-2014. The purpose of this study was to determine the relationship between knowledge and history of disease with premature birth at the Padangsidimpuan City General Hospital. This type of research is an analytic study with a cross sectional approach. The population was all mothers who gave birth prematurely and not prematurely at the Padangsidimpuan City Hospital. The sample in this study was the entire population of 92 people. The sample in this study amounted to 92 people. Data were collected through medical records and interviews using a questionnaire. Data were analyzed by univariate, bivariate using Chi-Square test at 95% confidence level (P < 0.05). The results showed that there was a relationship between medical history (p= 0.0001) and preterm birth, while the knowledge variable (p=0.061) was not related to preterm birth. It is recommended for health workers to further optimize health services by conducting antenatal care examinations according to standards to determine blood pressure, Hb levels, blood glucose in the prevention of preeclampsia, anemia, diabetes mellitus which can be at risk of prematurity. Padangsidimpuan City Hospital is expected to improve health counseling to mothers about a good age for pregnancy and childbirth, namely at the age of 20-34 years. The health office is expected to develop an atmosphere for community groups through perwiritan in socializing about prematurity

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Gileles-Hillel, Alex, Ira Erlichman, and Joel Reiter. "Apnea of Prematurity: An Update." Journal of Child Science 09, no. 01 (January 2019): e50-e58. http://dx.doi.org/10.1055/s-0039-1678669.

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AbstractApnea of prematurity (AOP) affects the majority of infants born prematurely, before 34 weeks of gestational age. AOP is a common diagnosis in the neonatal intensive care unit and one of significant clinical importance, both immediate and long term, as it is associated with reduced survival and poorer respiratory and neurodevelopmental outcomes. In this review, we provide an up-to-date summary of recent advances in the understanding of the pathophysiology of AOP, as well as the clinical questions relevant to physicians and staff treating infants with AOP. Finally, we discuss monitoring and discharge decisions, as these are areas of significant uncertainty.

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Costello, John M., Faith Kim, Richard Polin, and Ganga Krishnamurthy. "Double Jeopardy: Prematurity and Congenital Heart Disease—What's Known and Why It's Important." World Journal for Pediatric and Congenital Heart Surgery 13, no. 1 (December 17, 2021): 65–71. http://dx.doi.org/10.1177/21501351211062606.

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This article is based on a composite of talks presented during the Double Jeopardy: Prematurity and Congenital Heart Disease Plenary Session at NeoHeart 2020, a global virtual conference. Prematurity and low weight remain significant risk factors for mortality after neonatal cardiac surgery despite a steady increase in survival. Newer and lower weight thresholds for operability are constantly generated as surgeons gather proficiency, technical mastery, and experience in performing complex procedures on extremely small infants. The relationship between birth weight and survival after cardiac surgery is nonlinear with 2 kilograms (kg) being an inflection point below which marked decline in survival occurs. The prevalence of congenital heart disease (CHD) in premature infants is more than twice that in term born infants. Increased risk of preterm birth in infants with CHD is most commonly due to spontaneous preterm birth and remains poorly understood. Advances in Neonatal-Perinatal medicine have led to a marked improvement in survival of neonates born prematurely over the last several decades. However, the risk of severe morbidities including retinopathy of prematurity, intraventricular hemorrhage, bronchopulmonary dysplasia and necrotizing enterocolitis remains significant in extremely low birth weight infants. Premature infants with CHD are at a greater risk of prematurity related morbidities than premature infants without CHD. Interventions that have been successful in decreasing the risk of these morbidities are addressed.

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16

Howse, J. L., and M. Katz. "Conquering Prematurity." PEDIATRICS 131, no. 1 (December 31, 2012): 1–2. http://dx.doi.org/10.1542/peds.2012-2432.

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Moos, Merry-K. "Understanding Prematurity." AWHONN Lifelines 8, no. 1 (February 2004): 32–37. http://dx.doi.org/10.1177/1091592304263957.

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GRABER, EDWARD A. "Prematurity 1992." Obstetrical & Gynecological Survey 47, no. 8 (August 1992): 521–24. http://dx.doi.org/10.1097/00006254-199208000-00002.

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19

Semchyshyn, Stefan. "Prematurity prevention." American Journal of Obstetrics and Gynecology 172, no. 5 (May 1995): 1639–40. http://dx.doi.org/10.1016/0002-9378(95)90519-7.

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20

Goldson, Edward. "Prematurity: Discussion." International Journal of Behavioral Development 19, no. 3 (September 1996): 465–75. http://dx.doi.org/10.1177/016502549601900301.

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Goldson, Edward. "Prematurity: Discussion." International Journal of Behavioral Development 19, no. 3 (September 1, 1996): 465–76. http://dx.doi.org/10.1080/016502596385631.

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Papiernik, Emile. "Preventing Prematurity." JAMA: The Journal of the American Medical Association 262, no. 22 (December 8, 1989): 3128. http://dx.doi.org/10.1001/jama.1989.03430220049014.

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23

Allen, Marilee C. "Overview: Prematurity." Mental Retardation and Developmental Disabilities Research Reviews 8, no. 4 (2002): 213–14. http://dx.doi.org/10.1002/mrdd.10048.

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Papiernik, E. "Preventing prematurity." JAMA: The Journal of the American Medical Association 262, no. 22 (December 8, 1989): 3128–29. http://dx.doi.org/10.1001/jama.262.22.3128.

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Vainder, Marina, and Dan Farine. "Late Prematurity." Donald School Journal of Ultrasound in Obstetrics and Gynecology 17, no. 2 (July 5, 2023): 107–8. http://dx.doi.org/10.5005/jp-journals-10009-1973.

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Panova, I. E., G. N. Kireeva, Irina Aleksandrovna Chervonyak, and E. P. Tagieva. "ORGANIZATION OF PROVISION OF THE OPHTHALMOLOGICAL CARE FOR THE CHILDREN PRESENTING WITH RETINOPATHY OF PREMATURITY IN THE CHELYABINSK REGION UNDER CONDITIONS OF TRANSITION TO THE INTERNATIONAL CRITERIA FOR LIVE BIRTH." Russian Pediatric Ophthalmology 12, no. 3 (September 15, 2017): 139–44. http://dx.doi.org/10.18821/1993-1859-2017-12-3-139-144.

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Aim. The objective of the present study was to contribute to the improvement of the work of the services providing the ophthalmological care for the children presenting with retinopathy of prematurity in the Chelyabinsk region based on the analysis of the main characteristics of their activities under conditions of transition to the international criteria for live birth. Materials and methods. We have elaborated the model for the organization of the ophthalmological aid to the children comprising the group of enhanced risk of development of retinopathy of prematurity based at a multi-disciplinary pediatric healthcare facility of the Chelyabinsk region. The analysis of its work covered the period of 7 years and included such characteristics as the prevalence of retinopathy of prematurity in the high-risk group with special reference to the severity of this condition, its threshold and terminal stages as well as the frequency of aggressive posterior retinopathy of prematurity. The overall prevalence of retinopathy of prematurity among the children’s population of the Chelyabinsk region during the period from 2009 till 2015 was estimated to amount to 36.4%. The threshold stage of this condition (including its aggressive posterior variant) was shown to have occurred in 26.7% of the examined children. Results. Despite the ever increasing survival rate among the extremely prematurely born infants, the number of the blind patients among those examined in the present study decreased by a factor of 4.5. The advantages of the proposed model for the provision of specialized ophthalmological care for the preterm children include the possibility of parallel monitoring the indicators of ophthalmological and somatic conditions of the children with the participation of the highly skilled physicians, anesthesiologists, and neonatologists. Conclusion. The results of this study can be used to further improve the quality of the screening for retinopathy of prematurity among the preterm infants and the adequate treatment of this condition for preserving vision in a greater number of such patients.

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Caffarelli, Carlo, Serena Gracci, Giuliana Giannì, and Roberto Bernardini. "Are Babies Born Preterm High-Risk Asthma Candidates?" Journal of Clinical Medicine 12, no. 16 (August 19, 2023): 5400. http://dx.doi.org/10.3390/jcm12165400.

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Among preterm infants, the risk of developing asthma is a matter of debate. This review discusses the state of the art of poorly understood prematurity-associated asthma. Impaired pulmonary function is common in children born prematurely. Preterm infants are prone to developing viral respiratory tract infections, bronchiolitis in the first year of life, and recurrent viral wheezing in preschool age. All of these conditions may precede asthma development. We also discuss the role of both atopic sensitization and intestinal microbiome and, consequently, immune maturation. Diet and pollution have been considered to better understand how prematurity could be associated with asthma. Understanding the effect of factors involved in asthma onset may pave the way to improve the prediction of this asthma phenotype.

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Aggarwal, David, Debasmita Majhi, and Tapas Ranjan Padhi. "Aicardi syndrome in a prematurely born baby with retinopathy of prematurity: eye as a window to a systemic pathology." BMJ Case Reports 13, no. 8 (August 2020): e235750. http://dx.doi.org/10.1136/bcr-2020-235750.

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Many of the ophthalmic pathologies can co-exist and when taken together can at times give a clue to a life-threatening systemic condition. Presented here is a case of Aicardi syndrome in a prematurely born baby with retinopathy of prematurity . Early diagnosis by the ophthalmologist helped the baby for a timely neurological attention.

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Saidasheva, E. I., E. V. Plotnikova, S. V. Bilichenko, and V. I. Shilina. "Organizational models of ophthalmic observation of premature children in pediatric follow-up." Russian Ophthalmological Journal 15, no. 4 (December 14, 2022): 84–88. http://dx.doi.org/10.21516/2072-0076-2022-15-4-84-88.

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Purpose: to assess the organizational effectiveness of ophthalmic observation of premature infants in pediatric follow-up in St. Petersburg. Material and methods. We analyzed the reports submitted by city interdistrict ophthalmological facilities for retinopathy of prematurity (ROP) and the observation department for premature infants for the period from July 1, 2018 to July 1, 2021 available at the children's multidisciplinary hospital. Results. In St. Petersburg, 6 interdistrict ophthalmological facilities perform regular monitoring of ROP children and a daytime in-patient clinic offers interdisciplinary treatment and early rehabilitation of infants with perinatal pathology accompanying severe prematurity. The data on the frequency of ROP and other visual disorders in children born prematurely are presented. Conclusions. Interdistrict observation facilities are a modern form of regular ophthalmic follow-up of premature infants of risk groups or ROP infants who live in conditions of a large city. A promising observation model of children with combined perinatal pathology and severe prematurity is the setting of a department (daytime in-patient facility) in the children's multidisciplinary hospital. This allows assessing the general health of this critical group of population" and ensure a timely start of combined interdisciplinary treatment and medical rehabilitation.

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Green, Elys A., Steven P. Garrick, Briana Peterson, Philip J. Berger, Robert Galinsky, Rod W. Hunt, Steven X. Cho, Jane E. Bourke, Marcel F. Nold, and Claudia A. Nold-Petry. "The Role of the Interleukin-1 Family in Complications of Prematurity." International Journal of Molecular Sciences 24, no. 3 (February 1, 2023): 2795. http://dx.doi.org/10.3390/ijms24032795.

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Preterm birth is a major contributor to neonatal morbidity and mortality. Complications of prematurity such as bronchopulmonary dysplasia (BPD, affecting the lung), pulmonary hypertension associated with BPD (BPD-PH, heart), white matter injury (WMI, brain), retinopathy of prematurity (ROP, eyes), necrotizing enterocolitis (NEC, gut) and sepsis are among the major causes of long-term morbidity in infants born prematurely. Though the origins are multifactorial, inflammation and in particular the imbalance of pro- and anti-inflammatory mediators is now recognized as a key driver of the pathophysiology underlying these illnesses. Here, we review the involvement of the interleukin (IL)-1 family in perinatal inflammation and its clinical implications, with a focus on the potential of these cytokines as therapeutic targets for the development of safe and effective treatments for early life inflammatory diseases.

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Poplawska, Karolina, Karolina Dudek, Maja Koziarz, Dominik Cieniawski, Tomasz Drożdż, Sylwester Śmiałek, Dorota Drożdż, and Przemko Kwinta. "Prematurity-Related Hypertension in Children and Adolescents." International Journal of Pediatrics 2012 (2012): 1–8. http://dx.doi.org/10.1155/2012/537936.

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Due to the functional and structural immaturity of different organ systems, preterms have a higher rate of morbidity and mortality. The prevention and treatment of the complications of prematurity is a major challenge in perinatal health care. Recently, there have been several multicenter research trials analysing the impact of prematurity or low birth weight on the health problems of children and adolescents. Many of these studies deal with the issue of pediatric hypertension. An analysis of 15 studies conducted in the years 1998–2011, in which blood pressure values in ex-preterm children were measured, was performed. Comparison was based on several issues: measurement method, cohorts age, size, and birthweight. It has been proven that hypertension occurs more often in former preterm infants; however the etiologic pathways that cause this condition still remain unclear. Moreover, pediatric hypertension is a significant problem, because of its transformation into adult hypertension and increased cardiovascular risk later in life. Therefore it is crucial to introduce wide-spread screening and detection of elevated blood pressure, especially among prematurely born children.

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Sinha, Prabha, Olakanmi Joseph, and Aoun Hakmi. "Optimum time interval for intertwin delivery for extreme prematurity in DCDA twin pregnancy. A case report and a literature review." Hellenic Journal of Obstetrics and Gynecology 17, no. 4 (October 3, 2018): 91–97. http://dx.doi.org/10.33574/hjog.1632.

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Due to increased use of ART delayed twin interval delivery has become a common occurrence. Multiple pregnancy is associated with high incidence of premature labour. Prematurity is the leading cause of neonatal morbidity and mortality all over the world as premature babies are at a greater risk of dying and has other health issues. Delivery of the presenting fetus usually followed by delivery of the second fetus shortly thereafter. There is no study available for the management of multifetal pregnancy, where one twin had delivered very prematurely and the time interval of the delivery for subsequent fetus. Conservation of pregnancy has good outcome when properly managed with careful surveillance. Survival rate increases by approximately 10% every week conserved in utero. Reservation persist in anticipation of increased maternal morbidity and mortality due to infection after conservative management.Time interval remains a dilemma in extreme prematurity.

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Kuznetsova, Y. D., I. B. Astasheva, and A. N. Zvereva. "Clinical cases of severe postoperative course in children with uveal complications of laser coagulation in retinopathy of prematurity." Modern technologies in ophtalmology, no. 1 (March 28, 2023): 397–403. http://dx.doi.org/10.25276/2312-4911-2023-1-397-403.

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The most likely complications of laser coagulation in the active stages of retinopathy of prematurityis the occurrence of a pronounced inflammatory process, which may requre surgical treatment. In most cases, a positive effect occurs after a single surgical intervention. Purpose. Analysis of three clinical cases of severe postoperative course in children with uveal complications of laser coagulation in retinopathy of prematurity. Discussion. In these cases, the severe course of the postoperative period was noted in somatically severe children, including those with severe bronchopulmonary dysplasia, with infectious diseases of various etiologies suffered in intrauterine and the early period of development, including after surgery. Conclusion. Children who have had uveitis after laser coagulation of the retina are subject to careful dynamic observation. It is necessary to conduct unscheduled examinations after infectious diseases. Keywords: retinopathy of prematurity, laser coagulation of retina, uveal complications, cataract

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Maltsev, S. V., S. Ya Volgina, V. D. Mendelevich, and T. A. Gaisina. "Clinicopsychologic correlations in teenagers being born with various rate of prematurity." Kazan medical journal 77, no. 4 (August 15, 1996): 264–66. http://dx.doi.org/10.17816/kazmj104516.

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The clinicopsychologic correlations in 69 children aged 14 to 15 years being born with various rate of prematurity are revealed. Kettells test is used for estimation of personal peculiarities. The general mental and behaviour disorders prevail in prematurely being born children. The essential personal characteristics of teenagers being born premature are social shyness, straightforwardness, low level of uneasiness. The data obtained show the presence of phychosocial desadaption in observed children.

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Olujic, Maja, Ana Oros, Aleksandra Bregun-Doronjski, and Gordana Velisavljev-Filipovic. "Tests of screening criteria for retinopathy of prematurity." Medical review 65, no. 9-10 (2012): 409–14. http://dx.doi.org/10.2298/mpns1210409o.

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Introduction. Retinopathy of prematurity is a disease of the eye, i.e. the retinal blood vessels, which occurs exclusively in premature infants. The level of blindness in one country depends on the level of development of neonatal care and the opportunities to implement screening. The aim of this study was to examine the possibilities of changing screening criteria, provided that not a single child was left out from the survey. Material and Methods. A two-year prospective study, which was carried out in the period from January 1st 2007 to December 31st 2008, included 191 premature infants who were treated at the Institute for Child and Youth Healthcare of Vojvodina. Results. Different inclusion criteria regarding body mass and gestational age were applied for screening retinopathy of prematurity and we assessed the coverage of the sample if certain screening criteria were applied. According to the results of the research, when the applied screening criterion was 37/2000, there was not a single case of a blind, prematurely born baby. Discussion. Great migrations of population as well as big differences in characteristics of premature infants together with underlying multi-factor diseases besides retinopathy of prematurity send a warning signal to be very cautious. Conclusion. Although this study has given ground to shift the limits of screening, we will adhere to broad screening criteria.

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Zhou, Tianwei, Pierre-Olivier Kassis, Patrick Hamel, Cynthia Qian, Sylvain Chemtob, Anne Monique Nuyt, and Thuy Luu. "21 Long-Term Ophthalmologic Outcome of Young Adults Born Extremely Preterm." Paediatrics & Child Health 26, Supplement_1 (October 1, 2021): e13-e14. http://dx.doi.org/10.1093/pch/pxab061.015.

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Abstract Primary Subject area Ophthalmology Background Retinopathy of prematurity (ROP) remains the dominant cause of severe visual impairment in childhood in North America and Europe. With the salient improvement in neonatal care since the 1980s, more and more very/extremely premature infants survived and are now reaching adulthood. Premature birth interferes with the critical period of retinal maturation and foveal development. The development of ROP further damages the retina and its vasculature. So far, outcome studies on visual functions and ocular structure in adults born preterm remain scarce. Objectives The first aim of this study is to describe the visual function and retinal structure in a cohort of young adults who were born prematurely. With the recognition of the insidious nature of ROP, we also aimed to investigate if ROP could exert a “second hit” beyond prematurity. Design/Methods This cross-sectional observational study compared visual function of young adults (18-29 years old) born prematurely (< 30 weeks of gestational age [GA]) versus full-term controls. Participants were categorized into three groups: preterm without ROP, preterm with ROP, and term. Comprehensive ophthalmologic examination was performed with blinding to preterm and ROP status. Best corrected visual acuity (BCVA) was assessed with a standardized linear Snellen chart and contrast sensitivity (CS) with the Vistech system. When analyzing BCVA, refractive errors, and contrast sensitivities, we further grouped data based on the strong eyes (better BCVA) and the weak eyes (worse BCVA). Area-under-the-curve (AUC) analysis was performed to gauge the overall CS. Group comparisons were done using ANOVA. Results In this study, 88 individuals born prematurely and 86 individuals born full-term were recruited. Among the strong eyes of the 3 groups, there was no significant difference for BCVA or refractive errors (see image). Among the weak eyes, the preterm with ROP group had the worst BCVA and refractive outcomes, compared to the preterm without ROP and term groups. In the strong eyes, the CS AUC of the preterm with ROP group (16.22 ± 2.69 p<0.0001) was significantly lower than both the preterm without ROP (18.13 ± 2.01) and term (19.55 ± 2.48) groups. In the weak eyes, the AUC of the 3 groups showed a significant and progressive decline from the term group (18.9 ± 2.84) to the preterm without ROP group (18.29 ± 2.14), then to the preterm with ROP group (15.24 ± 2.21). Conclusion In our cohort of young adults born preterm, prematurity alone did not affect their BCVA and refractive errors. However, ROP was independently associated with a lower BCVA, higher refractive errors, and a reduced contrast sensitivity. Our data have shown that prematurity and ROP have independent effects on contrast sensitivity. This study highlights the necessity of long-term ophthalmologic follow-ups for adults who were born prematurely.

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Bahassan, Abdulaziz, and Colin Depp. "IS BEING A PREMATURE OR HAVING ABNORMAL BIRTH WEIGHT ASSOCIATED WITH DEPRESSION AMONG 6 - 17 YEARS OLD U.S. CHILDREN?" Paediatrics & Child Health 23, suppl_1 (May 18, 2018): e51-e51. http://dx.doi.org/10.1093/pch/pxy054.130.

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Abstract BACKGROUND Reports in 2015 showed that premature birth rate in the United States increased when compared to 2014 data, and this was the first increment since 2007. Major complications of prematurity and birth weight abnormalities are well known, but other complications including mental health abnormalities require more investigation to understand their association well. OBJECTIVES We aimed in this study to determine if prematurity and birth weight abnormalities including very low birth weight (VLBW) and low birth weight (LBW) are associated with depression among United States children aged between six and seventeen years old. DESIGN/METHODS This is a cross sectional study using data from the National Survey of Children’s Health (NSCH) 2011–2012. When we applied our selection criteria, 84,182 children out of the total 95,677 NSCH population were selected. Our exclusion criteria were: age less than six years, child’s history of cerebral palsy, and mental retardation. Multivariable logistic regression was done to control for confounding effects when studying the association of prematurity, birth weight abnormalities and depression. RESULTS Our results reveal that 3.6% of our population had history of depression, 11% were born prematurely, 7.4% had low birth weight, and 1.5% had very low birth weight. Depression was more frequent in children who were born prematurely (prevalence 4.3%) when compared to children born at term. Different models were built to analyze the association between prematurity, birth weight abnormalities and depression. There was no detectable statistically significant association when controlling for demographic data (age, gender, race, family structure) and mental health risk factors (parental poor mental health, chronic health conditions) as well as other factors. Results reveal that children who had chronic health conditions or had adverse family experiences have greater odds of having depression. On the other hand, African-American, male, and younger (6–11 years old) children have lower odds of depression. CONCLUSION Further longitudinal studies are required to establish a causal relationship of behavioral and psychological complications, and to determine the biological mechanisms of brain development that could be associated with depression among premature infants or those who have birth weight abnormalities.

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Partha Haradhan Chowdhury, Dr, and Brinda Haren Shah. "Retinopathy of Prematurity." Acta Scientific Ophthalmology 4, no. 5 (April 16, 2021): 60–62. http://dx.doi.org/10.31080/asop.2021.04.0289.

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Bhende, PramodS. "Retinopathy of prematurity." Indian Journal of Ophthalmology 68, no. 13 (2020): 10. http://dx.doi.org/10.4103/ijo.ijo_2378_19.

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SHARMA, MUKTA, and Anil Chauhan. "Retinopathy of Prematurity." International Journal of Tropical Medicine and Public Health 7, no. 1 (2017): 4. http://dx.doi.org/10.5455/ijtmph/252656.

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SHARMA, MUKTA, and Anil Chauhan. "Retinopathy of Prematurity." International Journal of Tropical Medicine and Public Health 7, no. 1 (2017): 4. http://dx.doi.org/10.5455/252656/ijtmph.

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Chandra, Parijat. "Retinopathy of Prematurity." Delhi Journal of Ophthalmology 25, no. 3 (March 1, 2015): 198–206. http://dx.doi.org/10.7869/djo.108.

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Rathie, Neha. "Retinopathy of Prematurity." Delhi Journal of Ophthalmology 27, no. 2 (December 1, 2016): 92–96. http://dx.doi.org/10.7869/djo.216.

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Phelps, D. L. "Retinopathy of Prematurity." Pediatrics in Review 16, no. 2 (February 1, 1995): 50–56. http://dx.doi.org/10.1542/pir.16-2-50.

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Forghani, N., and T. Aye. "Hypothyroxinemia and Prematurity." NeoReviews 9, no. 2 (February 1, 2008): e66-e71. http://dx.doi.org/10.1542/neo.9-2-e66.

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İpek, Mehmet Sah, Ferhat Cekmez, and Mustafa Berber. "Osteopenia of prematurity." Medeniyet Medical Journal 30, no. 1 (March 30, 2015): 41–50. http://dx.doi.org/10.5222/mmj.2015.041.

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Schwartz, Rachel M. "What Price Prematurity?" Family Planning Perspectives 21, no. 4 (July 1989): 170. http://dx.doi.org/10.2307/2135808.

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Metz, Henry S. "Retinopathy of Prematurity." Journal of Pediatric Ophthalmology & Strabismus 23, no. 3 (May 1986): 155. http://dx.doi.org/10.3928/0191-3913-19860501-15.

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Phelps, Dale L. "Retinopathy of Prematurity." Pediatrics In Review 16, no. 2 (February 1, 1995): 50–56. http://dx.doi.org/10.1542/pir.16.2.50.

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Retinopathy of prematurity is a common disorder among extremely low-birthweight preterm infants and may cause total vision loss in as many as 2% to 4% of those weighing less than 2 pounds at birth. Regular examinations begun in the neonatal intensive care unit permit early detection and treatment of progressive ROP and allow a reduction in visual impairment. Infants whose ROP has regressed should continue to receive regular ophthalmologic follow-up for the detection and treatment of myopia and strabismus and, if they have cicatricial sequelae, late retinal detachments as teens or adults. Early intervention and special education programs are important for the children whose vision loss is significant.

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Steinweg, Sue Byrd, Harold C. Griffin, Linda W. Griffin, and Happy Gingras. "Retinopathy of Prematurity." RE:view: Rehabilitation and Education for Blindness and Visual Impairment 37, no. 1 (April 1, 2005): 32–41. http://dx.doi.org/10.3200/revu.37.1.32-41.

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