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Journal articles on the topic 'Premature morbidity'

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Author: Grafiati

Published: 10 December 2022

Last updated: 28 January 2023

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1

Safina, A. I., E. V. Volyanyuk, M. V. Potapova, and T. S. Fisheleva. "STATE OF HEALTH OF PREMATURE CHILDREN: ACCORDING TO THE DATA OF KAZAN CITY CATAMNESIS CENTER." Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics) 63, no. 5 (November 20, 2018): 192–96. http://dx.doi.org/10.21508/1027-4065-2018-63-5-192-196.

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The article presents the analysis of the health status of children born prematurely during the first year of their life. There is the comparison of morbidity rates for five years of the operation of the catamnesis center of Kazan. Profoundly premature children demonstrated the highest level of morbidity with more frequent pathologies of the central nervous system, respiratory organs, eyes and anemia of premature children. In 2017 there was a decrease in the frequency and severity of respiratory diseases (bronchopulmonary dysplasia with chronic respiratory insufficiency 1.6 times), the nervous system (severe ischemic and hypoxic-hemorrhagic lesions of CNS 2.7 times), eyes and its adnexa (a complicated retinopathy of premature children 1.7 times) in extremely premature infants.

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2

Clotea, Eliza, Roxana Georgiana Bors, Vlad Dima, Mihaela Plotogea, and Valentin Varlas. "Current therapies to reduce the risk of brain damage associated with preterm birth." Romanian Journal of Pediatrics 71, S2 (November 30, 2022): 69–73. http://dx.doi.org/10.37897/rjp.2022.s2.15.

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Premature birth is an important public health problem associated with increased perinatal morbidity and mortality rates. Due to the triggering mechanisms of premature birth as well as the immaturity of the fetal brain, it is more prone to injury. Thus, these premature babies have an increased risk of immediate neurological complications as well as late neurodevelopmental abnormalities, which can have lifelong repercussions. Prompt identification of fetal brain injury and their treatment, as well as the supervision at regular time intervals of the neurodevelopment of children born prematurely, are a real challenge for the medical system.

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3

Tarca, Elena, Simona Gavrilescu, Laura Florescu, Alina Mariela Murgu, Monica Ungureanu, Vasile Valeriu Lupu, and Dana Elena Mindru. "INFECTIONS AND PREMATURITY, IMPORTANT RISK FACTORS FOR NEONATAL MORBIDITY AND MORTALITY." Romanian Journal of Infectious Diseases 19, no. 4 (December 31, 2016): 222–25. http://dx.doi.org/10.37897/rjid.2016.4.2.

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Infant mortality is a major problem in developing countries and, unfortunately, this is the case of our country as well, given that Romania ranks first in the European Union in this respect, with an infant mortality rate of 9 ‰, compared to an average of roughly 4 ‰. Worldwide, over 15 million babies are born prematurely each year and, out of these, more than a million die due to prematurity and infections, which are the main risk factors for neonatal mortality. The risk of infection is several times higher in preterm newborns than in full-term newborns – about 80% of neonatal infections occur in premature infants. A significant proportion of the survivors of prematurity will have important neurological sequelae because of neonatal infections as well as of intracerebral bleeding or hypoxia at birth. Continuing medical education in both the general population and the medical sector is crucial in preventing premature births and neonatal infections and, consequently, in decreasing infant morbidity and mortality rates in our country.

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4

Supratiknyo, Supratiknyo, and Siti Mardiyah. "PERBEDAAN KADAR HEMOGLOBIN DAN STATUS GIZI PADA PERSALINAN NORMAL DAN PREMATUR." OKSITOSIN : Jurnal Ilmiah Kebidanan 4, no. 2 (August 1, 2017): 90–97. http://dx.doi.org/10.35316/oksitosin.v4i2.365.

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Premature was the main cause of 60-80% neonatal morbidity and mortality worldwide. Hemoglobin (Hb) and low nutritional status in pregnant women was one of the factors that can affect preterm labor. This study aims to determine differences in hemoglobin levels and nutritional status in normal and premature birth in Abdoer Rahem Situbondo hospital. The design used a comparative analitic with cross sectional approach. The study population was normal and premature delivery was 68 mothers. The sampling method used total sampling with 68 respondents samples, data collection technique with medical record and implemented in 2015. The results showed that there wa difference in Hb level and nutritional status in normal and premature labor. Chi-Square test results showed P-value = 0,000> 0.05 then H0 was ignored. So it can be concluded that there was a difference between hemoglobin levels and nutritional status in normal and premature labor. Keywords : Pregnant Women, Hemoglobin Levels, Nutritional Status. ABSTRAK Prematur merupakan penyebab utama 60-80% morbiditas dan mortalitas neonatal di seluruh dunia. Hemoglobin (Hb) dan status gizi yang rendah pada ibu hamil salah satu faktor yang dapat mempengaruhi persalinan prematur. Penelitian ini bertujuan untuk mengetahui perbedaan kadar hemoglobin dan status gizi di normal dan kelahiran prematur di rumah sakit Abdoer Rahem Situbondo. Desainnya adalah analitik komparatif dengan pendekatan cross sectional. Populasi penelitian adalah normal dan prematur ibu melahirkan adalah 68 ibu. Metode sampling yang digunakan adalah total sampling dengan sampel 68 responden, teknik pengumpulan data pengambilan dengan rekam medis dan dilaksanakan pada tahun 2015. Hasil penelitian menunjukkan tidak ada perbedaan dalam tingkat Hb dan status gizi di persalinan normal dan prematur. Hasil uji Chi-Square menunjukkan bahwa hasil dari Pvalue = 0,000> 0,05 maka H0 ditolak. Jadi dapat disimpulkan bahwa ada perbedaan antara kadar hemoglobin dan status gizi di persalinan normal dan prematur. Kata kunci : Wanita Hamil, Kadar Hemoglobin, Status Gizi.

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5

Bukowski, Radek, George Saade, Joan Richardson, and Garland Anderson. "244 Growth potential versus morbidity in premature neonates." American Journal of Obstetrics and Gynecology 185, no. 6 (December 2001): S147. http://dx.doi.org/10.1016/s0002-9378(01)80277-5.

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6

Pleasure, Jeanette, Susan Gennaro, Avital Cnaan, and Francine Wolf. "An Expanded Neonatal Morbidity Scale for Premature Infants." Journal of Nursing Measurement 5, no. 2 (January 1997): 119–38. http://dx.doi.org/10.1891/1061-3749.5.2.119.

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We revised a neonatal morbidity scale (the NMS) that has served as a means for comparison of neonatal illness in studies of high-risk neonates after initial hospital discharge. With an inception cohort approach, 89 premature infants at an urban university hospital were studied with the expanded scale (the ENMS). The original scale, published in 1983, was reworked and expanded based on advances in the diagnosis and management of neonates. A social risk scale was added. Linear and logistic regression analyses were used to judge validity of the newly revised scale and to examine its predictive ability for outcomes at six months of age. Concurrent validity was supported by the relationship between the ENMS-SRS and: birthweight (R2 = .54), gestational age (R2 = .50), length of stay (R2 = .47). Inter-rater reliability was .95. The ENMS, embodying a contemporary patient profile, is valid for a population of premature infants in a U.S. urban setting and has predictive validity for a few outcomes within six months of discharge from a special care unit.

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7

McMurray, Jennifer. "The High-Risk Infant Is Going Home: What Now?" Neonatal Network 23, no. 1 (January 2004): 43–47. http://dx.doi.org/10.1891/0730-0832.23.1.43.

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EACH YEAR APPROXIMATELY 460,000 infants—nearly 12 percent of all babies born in the U.S.—are born prematurely.1 Technological advances in the medical and nursing care of premature infants over the past decade have increased survival rates among preterm newborns, especially of very low birth weight (VLBW) infants. Survival rates are as high as 49 percent for infants weighing 501–750 gm at birth, 85 percent for infants weighing 751–1,000 gm, 93 percent for infants weighing 1,001–1,250 gm, and 96 percent for infants weighing 1,251–1,500 gm.2 Although 50–60 percent of VLBW infants have normal outcomes, morbidity rates range from 40 to 50 percent.3 Because of this incidence of morbidity, premature infants require comprehensive primary care follow-up after discharge from the NICU.

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8

Student. "APGAR SCORES IN PREMATURE INFANTS." Pediatrics 84, no. 5 (November 1, 1989): A30. http://dx.doi.org/10.1542/peds.84.5.a30.

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9

Sinha, Prabha, Olakanmi Joseph, and Aoun Hakmi. "Optimum time interval for intertwin delivery for extreme prematurity in DCDA twin pregnancy. A case report and a literature review." Hellenic Journal of Obstetrics and Gynecology 17, no. 4 (October 3, 2018): 91–97. http://dx.doi.org/10.33574/hjog.1632.

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Due to increased use of ART delayed twin interval delivery has become a common occurrence. Multiple pregnancy is associated with high incidence of premature labour. Prematurity is the leading cause of neonatal morbidity and mortality all over the world as premature babies are at a greater risk of dying and has other health issues. Delivery of the presenting fetus usually followed by delivery of the second fetus shortly thereafter. There is no study available for the management of multifetal pregnancy, where one twin had delivered very prematurely and the time interval of the delivery for subsequent fetus. Conservation of pregnancy has good outcome when properly managed with careful surveillance. Survival rate increases by approximately 10% every week conserved in utero. Reservation persist in anticipation of increased maternal morbidity and mortality due to infection after conservative management.Time interval remains a dilemma in extreme prematurity.

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10

Hammerman, Cathy, and Mary Jane Aramburo. "Decreased lipid intake reduces morbidity in sick premature neonates." Journal of Pediatrics 113, no. 6 (December 1988): 1083–88. http://dx.doi.org/10.1016/s0022-3476(88)80587-0.

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11

Agbeko, Rachel S., and Mark J. Peters. "Mannose-binding lectin and pulmonary morbidity in premature infants." Intensive Care Medicine 34, no. 4 (January 24, 2008): 777. http://dx.doi.org/10.1007/s00134-008-1004-0.

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12

Seo, Kyung, James A. McGregor, and Janice I. French. "Infection and premature rupture of the membranes." Fetal and Maternal Medicine Review 2, no. 1 (January 1990): 1–19. http://dx.doi.org/10.1017/s0965539500000231.

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Premature rupture of the membranes (PROM) and preterm birthPreterm birth remains a paramount problem in health care worldwide. In the USA, approximately 6–10% of births occur preterm.1–3Gestational age at birth is the most important determinant of an infant's morbidity and mortality. Preterm infants account for approximately 75% of neonatal deaths,3–5as well as incalculable direct and indirect financial costs and morbidity.6–9

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13

Begum, Housneara, Marlina Roy, and Nahid Reaz Shapla. "Perinatal Outcome of Premature Rupture Membrane in Pregnancy." Journal of Dhaka Medical College 26, no. 2 (November 18, 2018): 135–39. http://dx.doi.org/10.3329/jdmc.v26i2.38831.

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Objective: To find out the effect of PROM on neonatal outcome so that we can pay more attention for the correct diagnosis and management of PROM in pregnancy which can reduce the perinatal mortality and morbidity caused by PROM.Methods: One hundred PROM cases were selected maintaining appropriate inclusion & exclusion criteria from the department of obstetrics & Gynaecology of BSMMU & DMCH and one hundred controlled cases were taken from the same during the period of January 2010 to December 2010. Data were analyzed with SPSS statistical program to determine the effect of PROM on neonatal health.Results: In this study, 44% babies of PROM patients had various type of morbidity compare to 24% of patients with intact membrane. In PROM patients, perinatal mortality was 7% in this study compare to 5% with intact membrane. Causes of perinatal death in PROM was severe asphyxia (4%), RDS (5%) & neonatal sepsis (6%) mainly.Conclusion: All fetal complications were significantly higher in PROM patients who received treatment after prolonged rupture of membrane. Appropriate antibiotic coverage in appropriate time will reduce fetal morbidity.J Dhaka Medical College, Vol. 26, No.2, October, 2017, Page 135-139

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14

MN., Amulya, and Ashwini MS. "Maternal outcome in term premature rupture of membranes." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 8, no. 2 (January 25, 2019): 576. http://dx.doi.org/10.18203/2320-1770.ijrcog20190287.

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Background: Rupture of Fetal membranes before the onset of labour is called PROM. Premature rupture of membrane (PROM) is associated with various complications. The present study is undertaken to study the maternal morbidity in term PROM.Methods: A prospective cross-sectional study was conducted at Vijaynagar institute of medical science Ballari for a period of one year by Department of Obstetrics and Gynecology from November 2016 to October 2017. 120 cases of spontaneous rupture of membranes with term gestation with confirmed PROM were selected.Results: PROM was common in age group of 20-29 years (80%), and common in primigravida. Study showed majority of them belongs to low socioeconomic status (80%) , 13.33% belonged to middle socioeconomic status and 6.66% belonged to higher socioeconomic status. In present study, it is observed that 27.05% cases went into spontaneous labour and delivered normally, 56.50% cases delivered by induction and 20% cases were delivered by LSCS. The rate of maternal morbidity was 16.6%, which includes febrile morbidity accounting to maximum with 9.6% followed by wound infection 3.33% and others were PPH(1.66%)and puerperal sepsis (each 1.66%).Conclusions: The rate of maternal morbidity was 16.6% and no maternal death observed. Hence an appropriate and accurate diagnosis of PROM is essential for favorable outcome in pregnancy and reduces the maternal morbidity.

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15

Costanzo, Caitlyn M., Charles Vinocur, and Loren Berman. "Prematurity Affects Age of Presentation of Pyloric Stenosis." Clinical Pediatrics 56, no. 2 (July 20, 2016): 127–31. http://dx.doi.org/10.1177/0009922816641367.

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Term infants with hypertrophic pyloric stenosis (HPS) typically present between 4 and 6 weeks. There is limited consensus, however, regarding age of presentation of premature infants. We aim to determine if there is an association between the degree of prematurity and chronological age of presentation of HPS. A total of 2988 infants who had undergone a pyloromyotomy for HPS were identified from the 2012 and 2013 NSQIP-P Participant Use Files. Two hundred seventeen infants (7.3%) were born prematurely. A greater degree of prematurity was associated with an older chronological age of presentation ( P < .0001). Prematurity was significantly associated with an increase in overall postoperative morbidity, reintubation, readmission, and postoperative length of stay. When clinicians evaluate an infant with nonbilious emesis with a history of prematurity, they should consider pyloric stenosis if the calculated postconceptional age is between 44 and 50 weeks. When counseling families of premature infants, surgeons should discuss the increased incidence of postpyloromyotomy morbidity.

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16

Orazmuradov, Agamurad, Igor Kostin, Anastasiya Akhmatova, Kemer Damirov, Irina Savenkova, Gayane Arakelyan, Khalid Haddad, Alexander Lopatin, Sergey Kyrtikov, and Aleksey Lukaev. "The Results of Bacteriological Examination in Premature Infants with Neonatal Morbidity and Mortality." International Journal of Biomedicine 10, no. 4 (December 10, 2020): 357–61. http://dx.doi.org/10.21103/article10(4)_oa5.

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The purpose of this study was to assess the results of bacteriological studies in children born prematurely and compare the received data with the detected neonatal morbidity. Methods and Results: Our study included 227 pregnant women at gestational age of 28-36 weeks 6 days, and their newborns. Depending on the gestational age, they were divided into 3 groups. Group 1 included 73 women at gestational age of 28-30 weeks 6 days; Group 2 included 81 women at gestational age of 31-33 weeks 6 days, Group 3 included 73 women at gestational age of 34-36 weeks 6 days. All women underwent an assessment of vaginal microcenosis and the quantitative and qualitative composition of the biotope of the cervical discharge; the newborns underwent bacteriological examination of the auricle, pharynx and anus. Analysis of the results of bacteriological studies shows a significant growth of microorganisms in newborns from mothers of Group 1. The analysis of morbidity among premature infants showed that in each group there were 2 or 3 diseases, mainly of an infectious nature. The main proportion of morbidity (congenital pneumonia and infections of the perinatal period, diseases of the urinary system, neonatal jaundice of premature infants and cerebral ischemia}.among newborns was found in Group 1, compared with Groups 2 and 3. The analysis of the results obtained showed that the low birth weight in preterm labor correlated with the growth of Staphylococcus epidermidis in the throat of newborns. Neonatal jaundice of premature newborns was characterized by 100% detection of Staphylococcus epidermidis and Serratia odorifera in the anus swabs, and Staphylococcus epidermidis in swabs from the pharynx and ear. Congenital pneumonia positively correlated with the growth of Staphylococcus epidermidis, E. coli, Candida spp, Enterococcus faecalis in the throat swab. The deceased children had a co-infection. Conclusion: Our study identified the main microorganisms affecting both perinatal morbidity and neonatal mortality: Staphylococcus epidermidis, Enterococcus faecalis, E. coli, Candida spp. It is necessary to note the frequent identification of E. coli strains resistant to the main antibacterial drugs.

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Boechat, Márcia Cristina Bastos, Rosane Reis de Mello, Kátia Silveira da Silva, Pedro Daltro, Edson Marchiori, Eloane Guimarães Ramos, and Maria Virgínia Peixoto Dutra. "A computed tomography scoring system to assess pulmonary disease among premature infants." Sao Paulo Medical Journal 128, no. 6 (December 2010): 328–35. http://dx.doi.org/10.1590/s1516-31802010000600004.

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CONTEXT AND OBJECTIVE: High-resolution computed tomography (HRCT) is considered to be the best method for detailed pulmonary evaluation. The aim here was to describe a scoring system based on abnormalities identified on HRCT among premature infants, and measure the predictive validity of the score in relation to respiratory morbidity during the first year of life. DESIGN AND SETTING: Prospective cohort study in Instituto Fernandes Figueira, Fundação Oswaldo Cruz. METHODS: Scoring system based on HRCT abnormalities among premature newborns. The affected lung area was quantified according to the number of compromised lobes, in addition to bilateral pulmonary involvement. Two radiologists applied the score to 86 HRCT scans. Intraobserver and interobserver agreement were analyzed. The score properties were calculated in relation to predictions of respiratory morbidity during the first year of life. RESULTS: Most of the patients (85%) presented abnormalities on HRCT, and among these, 56.2% presented respiratory morbidity during the first year of life. Scores ranged from zero to 12. There was good agreement between observers (intraclass correlation coefficient, ICC = 0.86, confidence interval, CI: 0.64-0.83). The predictive scores were as follows: positive predictive value 81.8%, negative predictive value 56.3%, sensitivity 39.1%, and specificity 90.0%. CONCLUSION: The scoring system is reproducible, easy to apply and allows HRCT comparisons among premature infants, by identifying patients with greater likelihood of respiratory morbidity during the first year of life. Its use will enable HRCT comparisons among premature infants with different risk factors for respiratory morbidity.

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18

Oyedele, Akinyemi, Morakinyo Oyedele, and Andrey V. Murashko. "Nursing profoundly premature newborns with artificial placentae: a review." V.F.Snegirev Archives of Obstetrics and Gynecology 8, no. 4 (December 15, 2021): 185–90. http://dx.doi.org/10.17816/2313-8726-2021-8-4-185-190.

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Neonatal mortality and morbidity are substantial issues affecting the maternal healthcare sector. Extremely premature infants, notably those born before the 28-week mark, experience significant morbidity and mortality rates during neonatal care. This is a result of developmental immaturity and iatrogenic injury. Several attempts have been made to develop a womb-like environment to mimic uteroplacental physiology, but limited success has been noted over the last decade. This review aims to summarize the current literature on improved techniques implemented in creating an artificial placenta, the principles of these procedures, and their limitations. Our findings indicate that implementing techniques that closely mimic uteroplacental pathophysiology is crucial in decreasing the excessive neonatal mortality and morbidity rates seen in extremely premature infants.

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19

Khade, Shweta Avinash, and Amarjeet Kaur Bava. "Preterm premature rupture of membranes: maternal and perinatal outcome." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 7, no. 11 (October 25, 2018): 4499. http://dx.doi.org/10.18203/2320-1770.ijrcog20184496.

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Background: This is an observational analytical study carried out in department of obstetrics and Gynecology, in a tertiary care center to determine the factors influencing fetal and maternal outcome, prognosis and complications in preterm premature rupture of membrane cases.Methods: The present study is a prospective observational study of perinatal and maternal outcome in 100 cases of preterm premature rupture of membranes in between 2837 weeks gestation with singleton pregnancy, from 1st March 2013 to 28th February 2014. Patients with medical complications like anemia, preexisting hypertension, diabetes, vascular or renal disease, multiple gestations, uterine or fetal anomalies etc. are excluded from the study. Detailed history, physical examinations were carried out and appropriate management instituted as per individual patients need.Results: In this study maternal morbidity was 16%. Perinatal morbidity was 33% and most common causes were hyperbilirubinemia (23%), RDS (21%). Perinatal mortality was seen in 15% and mainly due to RDS (53%). Twenty-five (25%) neonates were delivered by cesarean. The main indications for cesarean being malpresentation (36%) followed by fetal distress (24%).Conclusions: PPROM is one of the important causes of preterm birth that can result in high perinatal morbidity and mortality along with maternal morbidity. Looking after a premature infant puts immense burden on the family, economy and health care resources of the country. An understanding of gestational age dependent neonatal morbidity and mortality is important in determining the potential benefits of conservative management of preterm PROM at any gestation.

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20

Klein, Jonathan M. "NEONATAL MORBIDITY AND MORTALITY SECONDARY TO PREMATURE RUPTURE OF MEMBRANES." Obstetrics and Gynecology Clinics of North America 19, no. 2 (June 1992): 265–80. http://dx.doi.org/10.1016/s0889-8545(21)00349-1.

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21

Samet, Jonathan M. "Estimating the burden of smoking: premature mortality, morbidity, and costs." Salud Pública de México 52 (2010): S98—S107. http://dx.doi.org/10.1590/s0036-36342010000800005.

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22

Mei-Dan, Elad, Jyotsna Shah, Anne Synnes, Sandesh Shivananda, Greg Ryan, Prakeshkumar Shah, and Kellie Murphy. "721: Neonatal mortality and morbidity in early premature second twin." American Journal of Obstetrics and Gynecology 212, no. 1 (January 2015): S351. http://dx.doi.org/10.1016/j.ajog.2014.10.927.

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23

Goldsmith, Lowell A. "Comorbidity: Preventable Premature Morbidity and Mortality Due to Skin Disease." Journal of Investigative Dermatology 130, no. 9 (September 2010): 2155–56. http://dx.doi.org/10.1038/jid.2010.134.

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24

Garite, Thomas J., Reese Clark, and James A. Thorp. "Intrauterine growth restriction increases morbidity and mortality among premature neonates." American Journal of Obstetrics and Gynecology 191, no. 2 (August 2004): 481–87. http://dx.doi.org/10.1016/j.ajog.2004.01.036.

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Todorov, Iv, N. Tododrov, M. Angelova, and K. Peeva. "PREGNANCY RELATED PLASMA PROTEIN–A AND PREMATURE BIRTH." Trakia Journal of Sciences 19, no. 2 (2021): 172–77. http://dx.doi.org/10.15547/tjs.2021.02.010.

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Introduction: Children born prematurely are at higher risk of mortality, morbidity, and impaired motor and cognitive development in childhood than prematurely born babies. Aim: To establish the relationship between the corresponding levels of pregnancy-related plasma protein-A (PAPP-A) and the frequency of premature birth. Materials and methods: The study is prospective. The data was collected through monitoring patients through a questionnaire and sonographic examination at 11-13 gestational weeks. The study excluded all known risk factors for preterm birth, such as previous preterm births, pregnant women with gestational diabetes, preeclampsia, hypertension, placenta previa, hydramnion, multiple pregnancies, smoking, structural and chromosomal abnormalities of the fetus and planned preterm birth. The data from the measured values of PAPP-A and the frequency of premature birth in 636 pregnant women were analyzed. Conclusions: PAPP-A levels are a statistically significant factor for preterm birth. It is expected with a 95% probability in the population with PAPP-A values below 0,515 that the cases with premature birth will be from 7 to 14 times more. Pregnant women with PAPP-A level less than 10th per cent are significantly associated with an increased risk of preterm birth.

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Kulakov, Vladimir I., Vladimir N. Serov, and Vera M. Sidelnikova. "Prematurely delivery — observation tactics with account to gestation terms." Journal of obstetrics and women's diseases 51, no. 2 (April 14, 2002): 13–17. http://dx.doi.org/10.17816/jowd90371.

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Some disputable matters according to the problem of prematurely labor were presented in this article. The urgency of the problem is due to the fact that preterm birth determines the level of perinatal mortality and morbidity. The management of labor is determined by the gestational age. Termination of pregnancy in the period of 22-27 weeks is most often due to infection and fetal malformations, determined by this period of gestation. With a gestational age of 28-33 weeks, the percentage of indicated premature births is extremely high due to a complicated course of pregnancy (preeclampsia, placental insufficiency) and severe extragenital diseases. Premature birth at 34-37 weeks is close to timely delivery in terms of labor outcomes.

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27

Dmitrieva, T. E., and V. F. Fomina. "Ecological and economic assessment of public health in the Komi Republic." Arctic: Ecology and Economy 11, no. 3 (September 2021): 436–48. http://dx.doi.org/10.25283/2223-4594-2021-3-436-448.

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The authors assess the economic damage caused by the morbidity and mortality of the working-age population and identify the negative impact of environmental factors on the state of health at the municipal level. To achieve this the authors studied morbidity and mortality of the population in the region and in the municipalities over the past five years according to the international classification of diseases. Via foreign and domestic methodology for assessing, they also analyzed the degree and the spatial structure of the impact of the environmental factors on public health. Of the two international approaches to measure lost labor income due to premature death and diseases — “costly” and “profitable” — the authors used the second approach, adapted to the domestic information base and the available algorithm for calculating economic damage. Preliminary estimates of the lost profit from morbidity and premature mortality in the Komi Republic have determined the value of the unproduced GRP by years of the period from the impact of all causes for 1.5% of its total volume. The main sources of lost profits due to premature mortality are cardiovascular diseases and cancer, and due to morbidity — musculoskeletal diseases and respiratory infections.

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Fox, Grenville F. "Available statistics on premature birth." Fetal and Maternal Medicine Review 13, no. 3 (August 2002): 195–211. http://dx.doi.org/10.1017/s0965539502000347.

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Premature birth is associated with substantial excess childhood mortality and morbidity and therefore represents an important public health problem worldwide. In the United Kingdom and other industrialised countries it is now the commonest cause of infant mortality. This review will outline the most recently available data for the incidence of premature birth at local, regional, national and international level, and compare them to previously published figures. Any variation in these incidences will be considered along with factors likely to account for these differences. Problems with data collection and analysis will also be discussed.

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29

BAXTER, L. "Mortality and morbidity for premature neonatesGilstrap L, Hauth J, Bell R, et al: Survival and short-term morbidity of the premature neonate.Obstet Gynecol65:37, 1985." Journal of Nurse-Midwifery 30, no. 3 (May 1985): 180. http://dx.doi.org/10.1016/0091-2182(85)90287-3.

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30

Velisavljev-Filipovic, Gordana. "An ultrasound protocol in premature infants with intracranial hemorrhage." Medical review 58, no. 3-4 (2005): 185–90. http://dx.doi.org/10.2298/mpns0504185v.

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Introduction. Prematurity is a great health problem in our country and in the world. There are more than 11% of premature births in America annually, and in Europe this rate is between 5-10%. In Vojvodina, 9% of babies are born prematurely. Intracranial hemorrhage takes a significant place in the morbidity of prematurely born children. Intracranial hemorrhage in premature newborn infants Incomplete CNS development of premature infants causes numerous complications, but it is also the factor which enables survival of extremely immature infants without sequelae. The management protocol depends on the level of hemorrhage. Early diagnosis of intracranial hemorrhage and determination of the level of hemorrhage are of utmost importance for disability prevention. Ultrasound in monitoring intracranial hemorrhage Brain monitoring of prematurely born babies is performed by ultrasound. This type of visualization has several advantages over other techniques: it is mobile, so called "bedside technique", it is relatively cheap, it may be repeated several times, it is possible to define the exact time of hemorrhage and monitor its absorption from day to day. Ultrasound is safe, and there is no ionized radiation. No sedation is required for ultrasound examination. The examination is not painful. Conclusion The frequency of ultrasound depends on the level of hemorrhage, presence or absence of ventriculomegally/ hydrocephalus, as well as on the surrounding cerebral parenchyma. .

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Sari, Ita Marlita, I. Made Arya Subadiyasa, and Fety Riani. "Hubungan Karakteristik Sosio-Demografi dengan Kejadian Persalinan Prematur di Rsud Cilegon." JURNAL ILMIAH KESEHATAN MASYARAKAT : Media Komunikasi Komunitas Kesehatan Masyarakat 13, no. 4 (December 14, 2021): 167–72. http://dx.doi.org/10.52022/jikm.v13i4.250.

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Abstrak Latar Belakang: Persalinan prematur merupakan salah satu tantangan penting yang menghambat penurunan angka kematian neonatal sejalan dengan target Tujuan Pembangunan Berkelanjutan (SDGs) 2030. Pada tahun 2015, sekitar 1 juta bayi di seluruh dunia meninggal karena komplikasi persalinan prematur. Indonesia sendiri menempati posisi ke-9 di dunia dengan angka kejadian persalinan prematur sebesar 15,5 bayi per 100 kelahiran hidup. Morbiditas bayi prematur berpengaruh secara fisik hingga tahap perkembangan selanjutnya dan menjadi beban psikologis dan finansial bagi bayi, ibu dan keluarga. Salah satu faktor yang diduga berhubungan dengan persalinan prematur adalah karakteristik sosial demografi yang meliputi usia ibu, latar belakang pendidikan ibu, dan status pekerjaan ibu. Penelitian ini bertujuan untuk mengetahui hubungan antara karakteristik sosio-demografis dengan kejadian persalinan prematur di RSUD Cilegon. Metode: Desain penelitian adalah studi kasus-kontrol dengan menggunakan data sekunder dari rekam medis RSUD Cilegon periode Januari 2015 sampai Juni 2016. Sampel kasus dipilih secara total sampling, sedangkan sampel kontrol dipilih secara simple random sampling dan mencocokkan jumlah sampel kontrol berdasarkan jumlah kasus per sampel per bulan. Metode analisis yang digunakan adalah analisis bivariat dengan uji chi-square, menilai odds ratio dan interval kepercayaan. Hasil: Analisis bivariat menghasilkan OR 1,44 (95% CI: 0,68-3,03) dengan p-value 0,34 pada ibu usia > 35 tahun, OR 1,76 (95% CI: 0,68-4,55) dengan p-value 0,24 pada ibu hamil wanita berlatar belakang pendidikan SD/sederajat, dan OR sebesar 0,72 (95% CI: 0,30 -1,72) dengan p-value 0,42 pada wanita hamil yang bekerja. Kesimpulan: Karakteristik sosiodemografi tidak berhubungan dengan persalinan prematur. Kata kunci: Persalinan prematur, Karakteristik sosio-demografi, Studi kasus-kontrol, Cilegon Abstract Background: The premature delivery is one of crucial challenges which hinders the reduction neonatal mortality aligned with the 2030 Sustainable Development Goals (SDGs) target. In 2015, around 1 million babies worldwide died due to complications of premature labor. Indonesia itself occupies the 9th position in the world with the incidence of premature birth of 15.5 babies per 100 live births. Morbidity of premature babies affects physically until the next stage of development and becomes a psychological and financial burden for the baby, mother and family. One of factors thought to be associated with prematur birth is socio-demographic characteristics which includes maternal age, educational background of mother, and working status of mother. The aim of this study was to determine the relationship between socio-demographic characteristics and premature delivery at RSUD Cilegon. Methods: The research design was a case-control study using secondary data from the medical records of RSUD Cilegon for the period January 2015 to June 2016. The case sample was selected by total sampling, while the control sample was selected by simple random sampling and matched the number of control samples based on the number of cases per sample by month. The analytical method was bivariate analysis with the chi-square test, assessing odds ratios and confidence intervals. Result: The bivariate analysis yielded OR of 1.44 (95% CI: 0.68-3.03) with p-value 0.34 in maternal age > 35 years old, OR of 1.76 (95% CI: 0.68 -4.55) with p-value 0.24 in pregnant women who was elementary school/equivalent for educational background, and OR of 0.72 (95% CI: 0.30 -1.72) with p-value 0.42 in pregnant women who was working. Conclusion: Sociodemographic characteristics were not associated with premature delivery. Keywords: Premature delivery, Socio-demographic characteristics, Case-control studies, Cilegon

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Lovereen, Salma, Mst Afroza Khanum, Nazlima Nargis, Shahanawaj Begum, and Rumana Afroze. "Maternal and Neonatal outcome in premature rupture of membranes." Bangladesh Journal of Medical Science 17, no. 3 (June 29, 2018): 479–83. http://dx.doi.org/10.3329/bjms.v17i3.37004.

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Objective: The objective of the study was to assess the maternal and neonatal outcome in premature rupture of membranes.Material and Methods: A prospective study was carried out in the department of Obstetrics &Gynae in Ibn Sina Medical College hospital from October’15 to September’16. The sample size was 110. The maternal and neonatal outcome of pre-labour rupture of membranes in both term and preterm pregnancies was observed and statistically analyzed.Results: Incidence of PROM (premature rupture of membrane) was commonly in primigravida (62.7%). Term PROM was higher (70.92%) than PPROM (29.09%). Aetiological analysis revealed cause is unknown in most of the cases. Infection in 26.4% cases, previous history of PROM 16.3% and history of recent coitus 9.09% cases. Patient delivered by vaginal route 70.91% and LSCS 29.09%. The PROM had higher maternal morbidity (27.8%) like post partum fever 11.8%, wound infection 4.5% and chorioamnionitis 3.6%. Also higher perinatal mortality (4.5%) and morbidity (26.4%) like respiratory distress syndrome 9.09%, birth asphyxia 4.5%, septicemia 5.8%.Conclusion: Antenatal diagnosis to prevent PROM by identifying the risk factors is an important tool in management. Steroid for fetal lung maturity, antibiotics to prevent fetal and maternal infection, induction and/or augmentation of labour in due time and skilled NICU support will speed delivery, reduce hospital stay and infection as well as decrease maternal morbidity and perinatal morbidity and mortality.Bangladesh Journal of Medical Science Vol.17(3) 2018 p.479-483

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Кузибаева and R. Kuzibaeva. "Causes And Effects of Premature Delivery." Journal of New Medical Technologies 22, no. 2 (February 25, 2015): 67–71. http://dx.doi.org/10.12737/11837.

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Premature delivery is the leading cause of perinatal morbidity and mortality of newborns. The article presents the analysis of preterm birth in the perinatal center of Tula region. Depending on the causes of premature birth the author formed three groups. The 1-st group (n=32) included spontaneous preterm births, the 2nd group (n=115) -premature birth as a result of prenatal rupture of membranes, the 3st group (n=180) included preterm births for medical reasons. In all three groups, the demographic data, age, and parity were analyzed. The problem is the development of complex diagnostic techniques for the purpose of prognosis and preventive measures for pregnant women, because at present the obtained results do not allow us to accurately predict a preterm birth and to identify clearly the criteria for their possible development. Reduction of morbidity and mortality in newborns can be achieved through the timely identification of pregnant women at high risk, methods of prevention of preterm birth, quality of treatment and nursing of low-birth-weight infants [1]. This is of paramount importance not only in the formation of a healthy generation from a very early period of their lives and health, but also for the reproductive potential of women in the future [8].

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Davidesko, Sharon, Tamar Wainstock, Eyal Sheiner, and Gali Pariente. "Long-Term Infectious Morbidity of Premature Infants: Is There a Critical Threshold?" Journal of Clinical Medicine 9, no. 9 (September 18, 2020): 3008. http://dx.doi.org/10.3390/jcm9093008.

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In this study, we sought to ascertain a relationship between gestational age at birth and infectious morbidity of the offspring via population-based cohort analysis comparing the long-term incidence of infectious morbidity in infants born preterm and stratified by extremity of prematurity (extreme preterm birth: 24 + 0–27 + 6, very preterm birth: 28 + 0–31 + 6, moderate to late preterm birth: 32 + 0−36 + 6 weeks of gestation, and term deliveries). Infectious morbidity included hospitalizations involving a predefined set of International Classification of Diseases 9 (ICD9) codes, as recorded in hospital records. A Kaplan–Meier survival curve compared cumulative incidence of infectious-related morbidity. A Cox proportional hazards model controlled for confounders and time to event. The study included 220,594 patients: 125 (0.1%) extreme preterm births, 784 (0.4%) very preterm births, 13,323 (6.0%) moderate to late preterm births, and 206,362 term deliveries. Offspring born preterm had significantly more infection-related hospitalizations (18.4%, 19.8%, 14.9%, and 11.0% for the aforementioned stratification, respectively, p < 0.001). Multivariate analysis found being born very or late to moderate preterm was independently associated with long-term infectious morbidity (adjusted hazard ratio (aHR) 1.5, 95% confidence interval (CI) 1.27–1.77 and aHR 1.23, 95% CI 1.17–1.3, respectively, p < 0.001). A comparable risk of long-term infectious morbidity was found in the two groups of premature births prior to 32 weeks gestation. In our population, a cutoff from 32 weeks and below demarks a significant increase in the risk of long-term infectious morbidity of the offspring.

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Ahmad, Kaashif Aqeeb, Monica Michelle Bennett, Samiya Fatima Ahmad, Reese Hunter Clark, and Veeral Nalin Tolia. "Morbidity and mortality with early pulmonary haemorrhage in preterm neonates." Archives of Disease in Childhood - Fetal and Neonatal Edition 104, no. 1 (January 27, 2018): F63—F68. http://dx.doi.org/10.1136/archdischild-2017-314172.

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ObjectiveThere are no large studies evaluating pulmonary haemorrhage (PH) in premature infants. We sought to quantify the clinical characteristics, morbidities and mortality associated with early PH.DesignData were abstracted from the Pediatrix Clinical Data Warehouse, a large de-identified data set. For incidence calculations, we included infants from 340 Pediatrix United States Neonatal Intensive Care Units from 2005 to 2014 without congenital anomalies. Infants <28 weeks’ gestation with PH within 7 days of birth were then matched with two controls for birth weight, gestational age, gender, antenatal steroid exposure, day of life 0 or 1 intubation and multiple gestation.ResultsFrom 596 411 total infants, we identified 2799 with a diagnosis of PH. Peak incidence was 86.9 cases per 1000 admissions for neonates born at 24 weeks’ gestation. We then identified 1476 infants <28 weeks’ gestation with an early PH diagnosis at ≤7 days of age of which 1363 (92.3%) were successfully matched. Patients with early PH had significantly higher exposure to poractant alfa (35.4% vs 28%), diagnosis of shock (63.7% vs 51%) and grade IV intraventricular haemorrhage (20.8% vs 6%). Patients with PH also had significantly higher mortality rates at 7 days of age (40.6% vs 18.9%), 30 days of age (54% vs 28.8%) and prior to discharge (56.9% vs 33.7).ConclusionIn this large cohort of premature infants, we found PH to be common among the most premature babies. Early PH was associated with significant morbidity and mortality in excess of 50%. A renewed focus on the underlying pathophysiology and prevention of PH is warranted.

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Danila, V., A. Curteza, and S. Balan. "INTERACTION OF CLOTHING IN THERMOREGULATION IN THE CASE OF PRETERM INFANTS." TEXTEH Proceedings 2021 (September 22, 2021): 222–28. http://dx.doi.org/10.35530/tt.2021.12.

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The paper presents a study about the thermoregulation in the case of premature babies and the importance and influence of their clothing in this complex process. The temperature of premature babies has to be between 36.5 - 37.5°C but, hypothermia (axillary temperature <36.5°C) is a common situation. This is primarily due to a large surface area and metabolic mass ratio that results in heat loss. Hypothermia among new-borns is considered an important contributor to neonatal morbidity and mortality. In this context, it has been identified that clothing products are recommended to maintain the optimal body temperature for those born prematurely. The elaborate clothing products aim at maintaining a thermal comfort and certain physiological indicators. Skin temperature and tactile sensations also play an important role in the growth and development of premature babies. In this regard, 15 premature infants were used as study subjects and their temperature profile was recorded. The proposed clothes aimed to maintain the baby's temperature in the normal range and provide a pleasant aesthetic appearance, while helping to improve the medical manipulations to which these children are subjected.

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Bokonbaeva, S. D., B. K. Urmatova, and E. G. Kim. "RISK FACTORS AND PATTERNS OF MORBIDITY AND MORTALITY IN PREMATURE BABIES." International Journal of Applied and Fundamental Research (Международный журнал прикладных и фундаментальных исследований), no. 6 2022 (2022): 27–33. http://dx.doi.org/10.17513/mjpfi.13393.

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Gezer, A., E. Parafit-Yalciner, O. Guralp, V. Yedigoz, T. Altinok, and R. Madazli. "Neonatal morbidity mortality outcomes in pre-term premature rupture of membranes." Journal of Obstetrics and Gynaecology 33, no. 1 (December 21, 2012): 38–42. http://dx.doi.org/10.3109/01443615.2012.729620.

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Markestad, T. "Early Death, Morbidity, and Need of Treatment Among Extremely Premature Infants." PEDIATRICS 115, no. 5 (May 1, 2005): 1289–98. http://dx.doi.org/10.1542/peds.2004-1482.

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Siebert, S., M. Jakob, U. Gembruch, P. Bartmann, and A. Heep. "Neonatal morbidity in preterm infants after preterm premature rupture of membranes." Journal of Neonatal-Perinatal Medicine 5, no. 1 (2012): 49–56. http://dx.doi.org/10.3233/npm-2012-51511.

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Perez, Geovanny F., Krishna Pancham, Shehlanoor Huseni, Amisha Jain, Carlos E. Rodriguez-Martinez, Diego Preciado, Mary C. Rose, and Gustavo Nino. "Rhinovirus-induced airway cytokines and respiratory morbidity in severely premature children." Pediatric Allergy and Immunology 26, no. 2 (March 2015): 145–52. http://dx.doi.org/10.1111/pai.12346.

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Binet, Marie-Eve, Emmanuel Bujold, Francine Lefebvre, Yves Tremblay, and Bruno Piedboeuf. "Role of Gender in Morbidity and Mortality of Extremely Premature Neonates." American Journal of Perinatology 29, no. 03 (August 4, 2011): 159–66. http://dx.doi.org/10.1055/s-0031-1284225.

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Thompson, P. J., A. Greenough, and K. Nicolaides. "Chronic respiratory morbidity after prolonged and premature rupture of the membranes." Archives of Disease in Childhood 65, no. 8 (August 1, 1990): 878–80. http://dx.doi.org/10.1136/adc.65.8.878.

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Stockman, J. A. "Early Death, Morbidity, and Need of Treatment Among Extremely Premature Infants." Yearbook of Pediatrics 2006 (January 2006): 375–77. http://dx.doi.org/10.1016/s0084-3954(07)70224-5.

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Sampalis, John S. "Morbidity and mortality after RSV-associated hospitalizations among premature Canadian infants." Journal of Pediatrics 143, no. 5 (November 2003): 150–56. http://dx.doi.org/10.1067/s0022-3476(03)00513-4.

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Batton, D. "Early Death, Morbidity, and Need of Treatment Among Extremely Premature Infants." Yearbook of Neonatal and Perinatal Medicine 2006 (January 2006): 329–32. http://dx.doi.org/10.1016/s8756-5005(08)70379-2.

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Greenough, A. "Risk factors for respiratory morbidity in infancy after very premature birth." Archives of Disease in Childhood - Fetal and Neonatal Edition 90, no. 4 (July 1, 2005): F320—f323. http://dx.doi.org/10.1136/adc.2004.062018.

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Ito, Masato, Masanori Tamura, and Fumihiko Namba. "Role of sex in morbidity and mortality of very premature neonates." Pediatrics International 59, no. 8 (July 14, 2017): 898–905. http://dx.doi.org/10.1111/ped.13320.

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Waldron, J. L., and R. Pesek. "Rhinovirus-Induced Airway Cytokines and Respiratory Morbidity in Severely Premature Children." PEDIATRICS 136, Supplement (December 1, 2015): S256—S257. http://dx.doi.org/10.1542/peds.2015-2776sss.

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Ciuffini, Francesca, Colin F. Robertson, and David G. Tingay. "How best to capture the respiratory consequences of prematurity?" European Respiratory Review 27, no. 147 (March 14, 2018): 170108. http://dx.doi.org/10.1183/16000617.0108-2017.

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Chronic respiratory morbidity is a common complication of premature birth, generally defined by the presence of bronchopulmonary dysplasia, both clinically and in trials of respiratory therapies. However, recent data have highlighted that bronchopulmonary dysplasia does not correlate with chronic respiratory morbidity in older children born preterm. Longitudinally evaluating pulmonary morbidity from early life through to childhood provides a more rational method of defining the continuum of chronic respiratory morbidity of prematurity, and offers new insights into the efficacy of neonatal respiratory interventions. The changing nature of preterm lung disease suggests that a multimodal approach using dynamic lung function assessment will be needed to assess the efficacy of a neonatal respiratory therapy and predict the long-term respiratory consequences of premature birth. Our aim is to review the literature regarding the long-term respiratory outcomes of neonatal respiratory strategies, the difficulties of assessing dynamic lung function in infants, and potential new solutions.

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