Dissertations / Theses on the topic 'Pregnancy Nutritional aspects'
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Klinger, Ingrid. "The nutritional status of pregnant women in relation to alcohol consumption during pregnancy, and pregnancy outcome." Thesis, Stellenbosch : University of Stellenbosch, 2004. http://hdl.handle.net/10019.1/16365.
Full textENGLISH ABSTRACT: Introduction: Heavy alcohol consumption during pregnancy is teratogenic.49-51 A woman’s nutritional requirements increase during pregnancy.4 The dangers of heavy drinking in the presence of malnutrition may put the fetus at a further disadvantage to normal development and life. Objectives: To determine the nutritional status of pregnant women in relation to alcohol consumption during pregnancy, and pregnancy outcome. To relate the combined effect of maternal alcohol consumption and nutritional status to pregnancy outcome. Study design: Prospective, longitudinal and cohort. Study population: Pregnant women attending Hanover Park MOU for pre-natal care. They were classified as subjects (heavy drinkers) or controls (light drinkers or abstainers), and 15 pairs were matched according to race, parity and gestational age at the onset of their participation in the study. Methodology: A skilled FARR worker determined the alcohol consumption of the individuals through a validated questionnaire, whilst the investigator gathered the study data blinded to the participants’ alcohol consumption status. The investigator conducted three interviews with the pregnant individuals. Anthropometrical, clinical and biochemical investigations were done and questionnaires completed to determine dietary intake, sociodemographics, health and eating habits. An experienced FARR paediatrician examined the newborns, assessing their anthropometric status, health and the presence of any alcohol-related signs. Results: The nutritional status of the matched subjects and controls did not differ significantly in terms of dietary intake, anthropometric or clinical assessment. There were significant differences between the 2 groups’ serum vitamin A values (p<0.0097). Significant associations were found between the mother and newborn data; specifically energy intake and gestational age at birth (p<0.0083), MUAC and birth weight (p<0.04), and weight gain and weight for age (p<0.0056). The participants’ energy intake also had a significant correlation with their weight gain during pregnancy (r=0.0389, p<0.01). The prevalence of FAS in the total population was 6.67%; a finding that confirms previously reported data in nearby Wellington, Western Cape.49 Conclusion: Some mothers’ good nutritional status did not protect their offspring against alcohol’s teratogenic effects. Nutritional status did have a few statistical significant effects on pregnancy. However, the investigator is of the opinion that the few significant findings were not enough to accept or reject the hypothesis; therefore, making the results inconclusive.
AFRIKAANSE OPSOMMING: Inleiding: Swaar alkoholgebruik tydens swangerskap is teratogenies.49-51 Vroue se voedingsbehoeftes verhoog met swangerskap.4 Die gevare van swaar alkoholgebruik in die teenwoordigheid van wanvoeding mag die fetus verhoed om normal te ontwikkel en groei. Doelwitte: Om die voedingstatus van swanger vroue te bepaal in verhouding met alkoholgebruik tydens swangerskap, en die swangerskapsuitkoms. Asook om die gekombineerde effek van die moeder se voedingstatus en alkoholgebruik op haar swangerskapsuitkoms te bepaal. Studie-ontwerp: Prospektief, longitudinaal en kohort. Studiepopulasie: Swanger vroue wat Hanover Park MOU besoek vir voorgeboorte sorg. Hulle is of as toetslinge (swaar drinkers) of as kontroles (ligte drinkers of geheelonthouers) geklassifiseer, en 15 pare is gepaar na aanleiding van ras, pariteit en gestasionele ouderdom by die aanvang van deelname aan die studie. Metodologie: ‘n Ervare SAVN lid het die individue se alkoholgebruik bepaal deur middel van ‘n gevalideerde vraelys. Die navorser was geblind vir die individue se alkoholgebruik. Die navorser het drie onderhoude gevoer met elke individu. Antropometriese, kliniese en biochemiese ondersoeke is gedoen. Vraelyste is voltooi om dieetinname, gesondheid, sosiodemografiese en eetgewoonte- inligting te versamel. ‘n Ervare SAVN pediater het alle pasgeborenes ondersoek om hulle antropometriese status, gesondheid en die teenwoordigheid van enige alkohol-verwante tekens te bepaal. Resultate: Die voedingstatus van die gepaarde toets-en kontrolegroepe het nie beduidend verskil in terme van dieetinname, antropometriese of kliniese evaluering nie. Daar was ‘n beduidende verskil tussen die 2 groepe se serum vitamien A vlakke (p<0.0097). Beduidende assosiasies is gevind tussen die moeder en pasgebore se data; naamlike tussen energie-inname en gestasionele ouderdom by geboorte (p<0.0083), bo-armomtrek en geboortegewig (p<0.0056), en gewigstoename tydens swangerskap en die baba se gewig vir ouderdom (p<0.0056). Die deelnemers se energie-inname het ook ‘n beduidende positiewe korrelasie met hul gewigstoename tydens swangerskap gehad (r=0.0389, p<0.01). Die prevalensie van FAS in die totale populasie was 6.67%; wat ook gevind is onlangs in die nabygeleë Wellington, Weskaap.49 Gevolgtrekking: Sommige moeders se goeie voedingstatus het nie hul kinders teen alkohol se teratogeniese effekte beskerm nie. Voedingstatus se effek op swangerskapsuitkoms was statisties beduidend in ‘n paar gevalle. Tog is die navorser van mening dat daar nie genoeg beduidende bewyse is om die nulhipotese te aanvaar of verwerp nie; dus is die gevolgtrekking onopgelos.
Lundqvist, Anette. "Nutritional aspects of behaviour and biology during pregnancy and postpartum." Doctoral thesis, Umeå universitet, Allmänmedicin, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-117427.
Full textBakgrund En välbalanserad näringsrik kost är viktig för den gravida kvinnan och det växande fostret, så även för deras framtida hälsa. En bristfällig kost kan utgöras av både överförbrukning av energirika livsmedel vilket kan leda till högre viktuppgång än vad som är hälsosamt och bristande intag av viktiga näringsämnen. Kostintag regleras av komplexa biologiska system där flera faktorer är inblandade däribland steroidhormonet allopregnanolon. Det övergripande syftet med denna avhandling är att under och efter graviditet beskriva kostintag, vitamin D-nivåer, kostinformation och kostförändringar och att studera allopregnanolons relation till viktökning. Metod Studie I var en kvalitativ studie med fokusgruppsintervjuer med 23 gravida kvinnor. Texten analyserades med innehållsanalys. Studie II var en kvantitativ tvärsnittsstudie som genomfördes i tidig graviditet (n = 209) och med en grupp icke-gravida kvinnor (kontrollgrupp) (n=206). Självrapporterade kostdata från ett frågeformulär analyserades med beskrivande, jämförande statistik och en klusteranalysmodell (Partial Least Squares modellering). Studie III hade en kvantitativ longitudinell design. Vitamin D-koncentrationer analyserades hos 184 kvinnor, vid fem tillfällen under graviditeten och efter förlossningen. Beskrivande, jämförande statistik och en linjär mixad regressionsmodell användes. Studie IV var en kvantitativ longitudinell studie med 60 kvinnor. Koncentrationerna av allopregnanolon analyserades vid graviditetsvecka 12 och 35. Beskrivande och jämförande statistik samt Spearman’s korrelation användes för att beskriva samband mellan viktökning och koncentrationer av allopregnanolon. Resultat Intervjuerna i studie I visade att kvinnor ville veta mer om olika typer av mat för att minska en eventuell risk för sina barn men kostinformation var delvis upp till dem själva att ta reda på. De VIII uttryckte känslor av osäkerhet och skuld om de råkat äta något ”förbjudet”. Rekommendationerna följdes så väl som möjligt, tillsammans med sunt förnuft för att hantera kostförändringar. Huvudteman var ”Söka information på egen hand”, ”Få professionell rådgivning när problem uppstår”, ”Känna sig osäker” och ”Ta ansvar med en nypa salt”. I studie II kunde man se vissa skillnader i kostmönster bland de gravida kvinnorna jämfört med kontrollgruppen: mindre intag av grönsaker (47 g/dag), potatis/ris/pasta (31 g/dag), kött/fisk (24 g/dag) och alkohol och tobak/snus och ett högre intag av kosttillskott. Både gravida kvinnor och kontrollgruppen hade lägre intag av folsyra via kosten med 45 % (gravida) och 22 % (kontrollgruppen) än de gällande rekommendationer som är (500 resp 400 g/dag). I studie III såg man att inta et av vitamin D var 34 % lägre än rekommendationen på 10 µg/dag. Minst en tredjedel av deltagarna hade otillräckliga plasma nivåer av vitamin D, under 50 nmol/L. Årstid var en stark faktor som påverkar det longitudinella mönstret. Graviditetsvecka, säsong, totala energiintaget, intaget av vitamin D och multivitamintillskott under de senaste 14 dagarna var faktorer som relaterade till Dvitaminnivåer. I studie IV sågs ett samband mellan allopregnanolon-koncentrationer vid graviditetsvecka 35 och viktökning från vecka 12 till 35 (p = 0,016). Det sågs också ett samband mellan ökningen av allopregnanolon (vecka 12–35) och viktökningen (se ovan) (p = 0,028). Slutsatser Kostrekommendationer beskrevs som motsägelsefulla och förvirrande och kostråden de fick uppfattades som otillräckliga. Kvinnorna tog itu med sina kostförändringar och sökte information på egen hand men hade önskat mer omfattande råd från barnmorskan. Intaget av vitaminer viktiga för graviditeten var lägre än rekommendationerna, vilket också bekräftas av låga plasmanivåer av D-vitamin hos cirka en tredjedel av de gravida kvinnorna. D-vitaminnivåerna nådde en topp i slutet av graviditeten. Graviditetsvecka och säsong på året påverkade D vitaminnivåer, så även intag via mat och kosttillskott. Orsakertill viktökning är komplexa och beror på många faktorer. Allopregnanolon är en faktor som sågs relatera till viktökningen hos de undersökta gravida kvinnorna.
Patel, Dipti. "The effect of nutritional assessment and counseling of underweight pregnant women enrolled in nutrition intervention project (NIP)." Thesis, This resource online, 1993. http://scholar.lib.vt.edu/theses/available/etd-06162009-063240/.
Full textCassettari, Maria Luiza [UNESP]. "Avaliação do estado nutricional de gestantes do município de Botucatu, quanto a macro e micro nutrientes em relação à renda no período de 1996-1998." Universidade Estadual Paulista (UNESP), 2002. http://hdl.handle.net/11449/94768.
Full textA gravidez é uma fase do ciclo de vida em que a nutrição desempenha um papel muito importante, uma vez que esta influência o produto da concepção. O objetivo deste estudo foi descrever o estado nutricional de gestantes do município de Botucatu que se localiza na região centro sul do estado de São Paulo, distando aproximadamente 230km da Capital. A população é predominantemente urbana. Foram estudadas 496 gestantes com idade de 13-43 anos submetidas a entrevista para obtenção de dados socioeconômicos, demográficos e dietéticos, e coleta de sangue. Dentre as mulheres 83% eram brancas. 30,5% de adolescente, a renda mostrou que 69% estava abaixo da linha de pobreza, a escolaridade mostrou 63% era baixa, 79% casada, 25% eram fumantes, 41% eram primigestas e 12% apresentaram positividade para o exame parasitológico. As medianas para as variáveis antropométricas (percentagem de gestantes abaixo do ponto de corte) foram para: peso pré gestacional-56,0 kg;(20), peso gestacional-58,1 kg (15); estatura -158 cm(9), índice de massa corpórea pré gestacional-22,0 kg/m2 (18,7), circunferência do braço-270 mm (8,0), prega tricipital-8,6 mm (4,0).O IMC, ainda detectou 17,5% acima da normalidade. O ganho de peso semanal foi 180 g, mostrando valores maiores nas gestantes com IMC abaixo da normalidade. As medianas da ingestão de nutrientes (percentagem de gestantes que ingerem menos que 100% do RDA) foram para : energia 2186 Kcal (73), proteína 64,5 g (42), vitamina A 647,6 mg (56), a tocoferol 4,3 mg (100), vitamina C 106,0 mg (30) e ferro 11,0 mg (99). Os exames bioquímicos mostraram as medianas (percentagem abaixo do ponto de corte): hemoglobina 13,0 g/dL (3),ferro 92mg/dL (13), saturação da transferrina...
Pregnancy is a life cycle where nutrition plays an important role once it influences the product of conception. This study aimed to describe nutritional status of pregnant women in Botucatu located in the southern part of the State of São Paulo, 230 km far from the capital (São Paulo City). Population is predominantly an urban one. Pregnant women (496) between 13 and 43 years old were studied and subjected to interviews to obtain social, economic, demographic, dietetic data a well as blood sampling. Within the women 83% were white, 30.5% adolescents and the income showed that 69% were down poverty line, education was low 63%; 79% were married, 25% were smokers, 41% were pregnant for the first time, and 12% were positive for parasitological exam. Medians and anthropometric variables (percentage of pregnant women below cut point) were: pre-gestational weight – 56.0 kg (20) gestational weight - 58.1 kg (15) height 158 cm (9) ; pre-gestational body mass index 22.0 kg/m2 (15.o); arm circumference 270 mm (8.0); tricipital fold 18.6 mm (4.0) . BMI also detected 15.5% above normality. Weekly weight gain was 180g, with higher values on below normal BMI pregnant women. Nutrients intake medians (percentage of pregnant women who intake less than 100 % of RDA) was: energy 2186 Kcal (73), protein 64.5g (42) , vitamin A 647.mg (56), a- tocopherol 4.3 mg (100), vitamin C 106.0 mg (30) and iron 11.0 mg (99). Biochemical examinations showed medians (percentage below cut point) : hemoglobin 13.0 g/dL (3), iron 92 μ/dL (13), transferrin saturation 30.0% (8), ferritine... (Complete abstract click electronic access below)
Mannion, Cynthia. "The prevalence and effects of dairy product restriction during pregnancy and lactation on maternal dietary adequacy and infant birthweight /." Thesis, McGill University, 2004. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=84291.
Full textJohansson, Madelene. "Analytical and nutritional aspects of folate in cereals /." Uppsala : Dept. of Food Science, Swedish University of Agricultural Sciences, 2005. http://epsilon.slu.se/200507.pdf.
Full textKroskey, Diane Lynn. "Factors affecting the nutritional status of pregnant women." Thesis, The University of Arizona, 1989. http://hdl.handle.net/10150/277084.
Full textCassettari, Maria Luiza. "Avaliação do estado nutricional de gestantes do município de Botucatu, quanto a macro e micro nutrientes em relação à renda no período de 1996-1998 /." Botucatu : [s.n.], 2002. http://hdl.handle.net/11449/94768.
Full textResumo: A gravidez é uma fase do ciclo de vida em que a nutrição desempenha um papel muito importante, uma vez que esta influência o produto da concepção. O objetivo deste estudo foi descrever o estado nutricional de gestantes do município de Botucatu que se localiza na região centro sul do estado de São Paulo, distando aproximadamente 230km da Capital. A população é predominantemente urbana. Foram estudadas 496 gestantes com idade de 13-43 anos submetidas a entrevista para obtenção de dados socioeconômicos, demográficos e dietéticos, e coleta de sangue. Dentre as mulheres 83% eram brancas. 30,5% de adolescente, a renda mostrou que 69% estava abaixo da linha de pobreza, a escolaridade mostrou 63% era baixa, 79% casada, 25% eram fumantes, 41% eram primigestas e 12% apresentaram positividade para o exame parasitológico. As medianas para as variáveis antropométricas (percentagem de gestantes abaixo do ponto de corte) foram para: peso pré gestacional-56,0 kg;(20), peso gestacional-58,1 kg (15); estatura -158 cm(9), índice de massa corpórea pré gestacional-22,0 kg/m2 (18,7), circunferência do braço-270 mm (8,0), prega tricipital-8,6 mm (4,0).O IMC, ainda detectou 17,5% acima da normalidade. O ganho de peso semanal foi 180 g, mostrando valores maiores nas gestantes com IMC abaixo da normalidade. As medianas da ingestão de nutrientes (percentagem de gestantes que ingerem menos que 100% do RDA) foram para : energia 2186 Kcal (73), proteína 64,5 g (42), vitamina A 647,6 mg (56), a tocoferol 4,3 mg (100), vitamina C 106,0 mg (30) e ferro 11,0 mg (99). Os exames bioquímicos mostraram as medianas (percentagem abaixo do ponto de corte): hemoglobina 13,0 g/dL (3),ferro 92mg/dL (13), saturação da transferrina... (Resumo completo, clicar acesso eletrônico abaixo)
Abstract: Pregnancy is a life cycle where nutrition plays an important role once it influences the product of conception. This study aimed to describe nutritional status of pregnant women in Botucatu located in the southern part of the State of São Paulo, 230 km far from the capital (São Paulo City). Population is predominantly an urban one. Pregnant women (496) between 13 and 43 years old were studied and subjected to interviews to obtain social, economic, demographic, dietetic data a well as blood sampling. Within the women 83% were white, 30.5% adolescents and the income showed that 69% were down poverty line, education was low 63%; 79% were married, 25% were smokers, 41% were pregnant for the first time, and 12% were positive for parasitological exam. Medians and anthropometric variables (percentage of pregnant women below cut point) were: pre-gestational weight - 56.0 kg (20) gestational weight - 58.1 kg (15) height 158 cm (9) ; pre-gestational body mass index 22.0 kg/m2 (15.o); arm circumference 270 mm (8.0); tricipital fold 18.6 mm (4.0) . BMI also detected 15.5% above normality. Weekly weight gain was 180g, with higher values on below normal BMI pregnant women. Nutrients intake medians (percentage of pregnant women who intake less than 100 % of RDA) was: energy 2186 Kcal (73), protein 64.5g (42) , vitamin A 647.mg (56), a- tocopherol 4.3 mg (100), vitamin C 106.0 mg (30) and iron 11.0 mg (99). Biochemical examinations showed medians (percentage below cut point) : hemoglobin 13.0 g/dL (3), iron 92 μ/dL (13), transferrin saturation 30.0% (8), ferritine... (Complete abstract click electronic access below)
Mestre
Tucker, Margaret Anne-Marie Kofa Jah. "The effect of nutritional status of women on the outcome of pregnancy in Sierra Leone, west Africa." Virtual Press, 1989. http://liblink.bsu.edu/uhtbin/catkey/560274.
Full textDepartment of Home Economics
Muscati, Siham K. (Siham Khalili). "The combined effect of nutritional factors on infant birth weight in teenage pregnancies /." Thesis, McGill University, 1987. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=66263.
Full textFergusson, Marjorie. "Comparison of dietary fructose versus glucose during pregnancy on fetal growth and development." Thesis, McGill University, 1989. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=59400.
Full textModjadji, Sewela Elizabeth Perpetua. "Nutritional factors involved in development of neural tube defects in offspring of women residing in a high risk area." Thesis, University of Limpopo ( Turfloop campus), 2009. http://hdl.handle.net/10386/1144.
Full textAIM: This study aimed to assess the nutritional status of non-pregnant women of childbearing age residing in a rural area of Limpopo Province, South Africa, and the effect of fortification of staple foods on their folate and iron status. The following objectives were carried out: To assess the socio-demographic status and maternity history of non-pregnant rural women of childbearing age. To determine the following anthropometric measurements; body weight, height, body mass index, waist and hip circumference, and waist hip ratio of women of childbearing age. To assess dietary intake of non-pregnant rural women of childbearing age using 24-hour recall and quantitative food frequency questionnaires prior to fortification of foods. To determine folate status of non-pregnant rural women of childbearing age by levels of serum and red blood cell folate, and assessing vitamin B12 and homocysteine levels before and after fortification of foods. To determine iron status of non-pregnant rural women of childbearing age by full blood count, serum ferritin, iron, total iron binding capacity, transferrin saturation and C–reactive protein before and after fortification of foods. To determine albumin and liver enzymes (ALP, ALT, AST and GGT) of women of childbearing age before and after fortification. To assess mycotoxins (i.e. fumonisins) in morogo samples collected randomly among participants from the study area.
the University of Limpopo Research Department,and the National Research Foundation
Leccisi-Esrey, Katja. "Joint effects of exercise and dietary carbohydrate on pregnancy outcome and early neonatal survival in rats." Thesis, McGill University, 1991. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=60534.
Full textCobrin, Mona. "The interaction of the level of dietary carbohydrate and exercise intensity during pregnancy on fetal growth and development /." Thesis, McGill University, 1993. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=69760.
Full textTorres, Esperanza. "THE EFFECTS OF CAFFEINE INGESTION ON FETAL HEART RATE IN PREGNANT COLOMBIAN WOMEN." Thesis, The University of Arizona, 1985. http://hdl.handle.net/10150/275340.
Full textLanoue, Louise. "The effects of graded levels of dietary carbohydrate on fetal and neonatal glucose metabolism." Thesis, McGill University, 1993. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=41670.
Full textChu, Tsz-wai Annie, and 朱梓慧. "An explorative longitudinal study of disordered eating attitudes and behaviors among pregnant women in Hong Kong." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2004. http://hub.hku.hk/bib/B29760033.
Full textDowning, Diane Elaine. "Maternal anthropometric measures and nutrient intake during the second and third trimesters of pregnancy of normal weight and overweight gravidas." Thesis, Virginia Polytechnic Institute and State University, 1986. http://hdl.handle.net/10919/101271.
Full textM.S.
Wang, Xingyue, and 王星月. "Diet and physical activity interventions to prevent excessive gestational weight gain : a systematic review." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2014. http://hdl.handle.net/10722/206966.
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Public Health
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Master of Public Health
Liu, Xu-Jing. "Effects of maternal dietary carbohydrate on phosphoenolpyruvate carboxykinase development in the fetus and neonate." Thesis, McGill University, 1995. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=23282.
Full textMuscati, Siham K. (Siham Khalili). "Balance between fetal growth and maternal weight retention : effects of maternal diet, weight and smoking behaviour." Thesis, McGill University, 1996. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=40405.
Full textParks, Sally A. "Calcium study : pregnant care coordination clients." Virtual Press, 1998. http://liblink.bsu.edu/uhtbin/catkey/1115427.
Full textMiniaci, Sandra A. "Maternal dietary glucose restriction and its effect on amniotic fluid amino acid composition." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape11/PQDD_0001/MQ44224.pdf.
Full textDavies, Hilary. "An investigation into the most appropriate prediction method for birth outcomes and maternal morbidity, and the influence of socioeconomic status in a group of preganant women in Khayelitsha, South Africa." Thesis, Stellenbosch : University of Stellenbosch, 2010. http://hdl.handle.net/10019.1/5235.
Full textENGLISH ABSTRACT: Introduction : The health status of women in peri-urban areas has been influence by the South African political transition. Despite some progress, maternal and child mortality rates are still unacceptably high. A mother’s nutritional status is one of the most important determinants of maternal and birth outcomes. The Institute of Medicine’s pre-pregnancy Body Mass Index (BMI) method is not always appropriate to use in a peri-urban setting as many women attend their first antenatal clinic later on in their pregnancy. Two alternative methods, the gestational BMI (GBMI) and the gestational risk score (GRS), have been used elsewhere to screen for at risk pregnancies, but have not been used in a South African peri-urban setting. Furthermore, examining socio-economic variables (SEV) aids in the explanation of the impact of social structures on an individual. Risk factors can then be established and pregnant women in these higher risk groups can be identified and given additional antenatal clinic appointments and priority during labour. Aim: The first aim was to investigate the strength of the GBMI and GRS methods for predicting birth outcomes and maternal morbidities. The second aim was to investigate the relationships between SEV, GBMI and maternal morbidities. Methods: This was a sub-study of the Philani Mentor Mothers Study. A sample of 103 and 205 were selected for investigating the prediction methods and SEV respectively. Maternal anthropometry, gestational weeks and SEV were obtained during interviews before birth. Information obtained was used to calculate GBMI and GRS and to assess the SEV. Birth outcomes were obtained from the infant’s clinic cards and maternal morbidities were obtained from interviews two days after the birth. Results No significant association was found between GBMI and birth outcomes and maternal morbidities. A significant positive association was found between GRS and birth head circumference percentile (r=0.22, p<0.05). The higher the GRS, the higher the risk of an infant spending longer time in the hospital (Kruskal Wallis X2 = 4, p<0.05). A significant positive association was found between GBMI and the following SEV factors; age (r=0.33, p<0.05), height (r=0.15, p<0.05), parity (r=0.23, p<0.05), income (r=0.2, p<0.05), marital status (X2 = 9.35, p<0.05), employment (U=2.9, p<0.05) and HIV status (U=2.54, p<0.05). No statistically significant relationships were found between gestational hypertension and gestational diabetes mellitus and SEV. Conclusion: From the findings of this sub-study there were some promising results, however it is still unclear as to which method is the most appropriate to predict adverse birth outcomes and maternal morbidity. It is recommended that the GBMI and GRS once-off methods be repeated in a larger population to see if there are more parameters that could be predicted. Women who were older, shorter, married, had more pregnancies, HIV negative and had a higher socioeconomic status tended to have a greater GBMI. This can lead to adverse birth outcomes and increases the risk of women developing maternal morbidities and other chronic diseases later in their life. Optimal nutrition and health promotion strategies targeting women before conception should be implemented.
AFRIKAANSE OPSOMMING: Inleiding: Die gesondheidstatus van vroue in semi-stedelike areas is beïnvloed deur die Suid-Afrikaanse politiese oorgang. Ten spyte van ’n mate van vooruitgang is die sterftesyfers vir moeders en kinders steeds onaanvaarbaar hoog. ‘n Moeder se voedingstatus is een van die mees belangrike bepalende faktore van moeder- en geboorteuitkomste. Die Instituut van Geneeskunde se voorswangerskap Liggaamsmassa Indeks (LMI) metode is nie altyd toepaslik om te gebruik in ‘n semi-stedelike opset nie aangesien baie vroue hul eerste voorgeboorte-kliniek eers later in hul swangerskap bywoon. Twee alternatiewe metodes, die swangerskap LMI (SLMI) en die swangerskap risiko telling (SRT) is al elders gebruik as sifting vir hoë risiko swangerskappe, maar is nog nie gebruik in ‘n Suid-Afrikaanse semi-stedelike opset nie. Vervolgens kan ‘n ondersoek na sosio-ekonomiese veranderlikes (SEV) help om die impak van maatskaplike strukture op ‘n individu te verduidelik. Risiko faktore kan dan vasgestel word en swanger vroue wat in hierdie hoër risiko groepe val kan geïdentifiseer word. Dié vroue kan addisionele voorgeboorte-kliniek afsprake ontvang asook voorkeurbehandeling tydens die geboorteproses. Doelstellings: Die eerste doelstelling was om die sterkte van die SLMI en SRT metodes te ondersoek as voorspellers van geboorte uitkomste en moeder-morbiditeite. Die tweede doelstelling was om die verhoudings tussen SEV, SLMI en moeder-morbiditeite te ondersoek. Metodes: Hierdie projek was ‘n sub-studie van die Philani Mentor Moeders Studie. ‘n Steekproefgrootte van 103 en 205 was geselekteer om onderskeidelik die voorspeller metodes en SEV te ondersoek. Die moeder se antropometrie, swangerskap weke en SEV was verkry gedurende onderhoude voor geboorte. Informasie ingewin was gebruik om die SLMI en SRT te bereken en om die SEV te ondersoek. Geboorteuitkomste was verkry vanaf die babas se kliniekkaarte en moeder-morbiditeite was verkry tydens onderhoude twee dae na die geboorte. Resultate: Geen betekenisvolle assosiasie was gevind tussen SLMI, geboorteuitkomste en moeder-morbiditeite nie. ‘n Betekenisvolle positiewe assosiasie was gevind tussen SRT en die geboorte kopomtrek persentiel (r=0.22, p<0.05). Hoe hoër die SRT, hoe hoër die risiko dat ‘n baba langer in die hospitaal sou bly (Kruskal Wallis X2=4, p<0.05). ‘n Betekenisvolle positiewe assosiasie was gevind tussen SLMI en die volgende SEV faktore: ouderdom (r=0.33, p<0.05), lengte (r=0.15, p<0.05), pariteit (r=0.23, p<0.05), inkomste (r=0.2, p<0.05), huwelikstatus (X2=9.35, p<0.05), besit van ‘n identiteitsdokument (U=1.75, p<0.05), werkstatus (U=2.9, p<0.05) en MIV status (U=2.54, p<0.05). Geen statisties beduidende verhoudings was gevind tussen swangerskap hipertensie, swangerskap diabetes mellitus en SEV nie. Gevolgtrekking Sommige bevindinge van hierdie sub-studie dui op belowende resultate, alhoewel dit steeds nie duidelik is watter metode die mees toepaslike is om ongewenste geboorteuitkomste en moeder-morbiditeit te voorspel nie. Dit word aanbeveel dat die SLMI en SRT eenmalige metodes herhaal word in ‘n groter populasie om te sien of daar meer parameters is wat voorspel kan word. Vroue wat ouer, korter, getroud, meer swangerskappe, MIV negatief en ‘n hoër sosio-ekonomiese status gehad het was geneig om ‘n hoër SLMI te hê. Dit kan lei tot ongewenste geboorteuitkomste en verhoogde risiko om moeder-morbiditeite en ander chroniese siektes later in hul lewe te ontwikkel. Optimale voeding en gesondheidsbevordering strategieë wat vroue teiken voor bevrugting behoort geïmplementeer te word.
Grundlingh, Heila. "Evaluation of the implementation of the nutritional supplementation programmes for pregnant women within the Cape Town Metropolitan Area." Thesis, Stellenbosch : Stellenbosch University, 2012. http://hdl.handle.net/10019.1/71851.
Full textENGLISH ABSTRACT: Introduction: The primary objective was to determine whether pregnant women visiting primary health care clinics (PHCs) were aware of the nutritional supplementation programmes: Nutrition Supplementation Programme (NSP) food, folate-, iron- and vitamin A supplementation. The secondary objective was to determine whether pregnant women qualified for the NSP food-, folate- and iron supplementation. The third objective was to determine whether those who qualified received the prescribed NSP food-, folate-, and iron supplementation and whether they were compliant with these interventions. Design: A cross-sectional descriptive study was conducted at all PHCs hosting basic antenatal clinics in the Cape Town Metropolitan Area of the Western Cape Province, South Africa. Method: One hundred and fourteen pregnant women who met the inclusion criteria were included in the study using a non-random quota sampling strategy. Pregnant women were interviewed using a validated questionnaire. The mid upper arm circumference (MUAC) was measured and the symphysis-fundus (SF) measurement was obtained from the medical files to determine whether participants met the entry criteria for the NSP. Written informed consent was obtained from participants. Results: Fifty per cent of participants were between 12 and 24 weeks of gestation. Most of them (68%) had an MUAC of between 24,7 cm and 34,4 cm. Fifty (44%) of the participants had a sufficient SF measurement. Twenty-one (18%) of the participants indicated that they were aware of the vitamin A Programme, 56 (49%) were aware of the NSP food-supplementation and 79 (70%) knew about the folicand iron supplementation that pregnant women should receive from the clinic. Six (5%) participants qualified for the NSP with an MUAC of below 23 cm. Only one (17%) participant was registered with the NSP and received the food-supplementation. Seventy (61%) of the participants indicated that they received and used the iron- and folic supplements, of which 30 (43%) did not know why they needed to take these supplements. Conclusion: Folate- and iron supplementation appears to be reasonably successfully implemented in the Cape Town Metropolitan Area among pregnant women visiting PHCs. The NSP food-supplementation, however, appears to be unsuccessfully implemented and needs further attention. Resources could be appointed to inform pregnant women about the reasons for and importance of taking these supplements.
AFRIKAANSE OPSOMMING: Inleiding: Die hoofdoelstelling was om te bepaal of swanger vroue wat primêre gesondheidsorgklinieke (PGK’s) bywoon, bewus was van die voeding supplementasie programme: Voedsel Supplementasie Program (VSP) – voedselaanvulling, folaat-, yster- en vitamien A supplementasie. Die tweede doelstelling was om te bepaal of hierdie swanger vroue in aanmerking kom vir die VSP– voedselaanvulling, folaat- en yster supplementasie. Die derde doelstelling was om te bepaal of hierdie swanger vroue die voorgeskrewe VSP – voedselaanvulling, folaat- en yster supplementasie ontvang het en hierdie intervensies nagevolg het. Ontwerp: ʼn Deursnit beskrywende studie is gedoen en data is ingesamel van al die PGK’s wat voorgeboortelike klinieke huisves in die Kaapstadse metropolitaanse gebied, in die Wes-Kaapprovinsie, Suid-Afrika. Metode: Honderd en veertien swanger vroue wat aan die insluitingskriteria voldoen het, is volgens ʼn nie-ewekansige kwotastrategie uitgesoek om aan die studie deel te neem. Onderhoude is volgens ʼn bevestigde vraelys met swanger vroue gevoer. Die omtrek van die middelboarm is geneem en die symphysis-fundus-meting is van die mediese lêers verkry om te bepaal of deelnemers aan die insluitingskriteria vir die VSP voldoen. Deelnemers het ʼn vrywaringsvorm geteken voordat hulle aan die studie begin deelneem het. Resultate: Vyftig persent van die swanger vroue het ʼn gestasie-ouderdom van tussen 12 en 24 weke gehad. Die omtrek van die meeste vroue (68%) se middelboarm was tussen 24,7 cm en 34,4 cm. Vyftig (44%) van die vroue se symphysis-fundusmeting was voldoende. Een en twintig (18%) van die deelnemers het aangedui dat hulle van die Vitamien A-program bewus was, 56 (49%) was van die VSPvoedselaanvulling bewus en 79 (70%) van die deelnemers was bewus van die folaat- en yster supplementasie wat swanger vroue van die kliniek behoort te ontvang. Ses (5%) deelnemers, met ʼn middelboarm-omtrek van minder as 23 cm, het vir die VSP in aanmerking gekom. Slegs een (17%) deelnemer was geregistreer en het die voedselaanvulling ontvang. Sewentig (61%) van die deelnemers het aangedui dat hul wel yster- en folaat supplementasie ontvang en gebruik, waarvan 30 (43%) nie geweet het waarom hulle dié supplemente neem nie. Gevolgtrekking: Dit wil voorkom asof folaat- en yster supplementasie vir swanger vroue wat PGK’s in die Kaapstadse metropolitaanse gebied besoek, redelik suksesvol toegepas word. Daarteenoor word die VSP – voedselaanvulling onsuksesvol uitgevoer en behoort dit verdere aandag te geniet. Hulpbronne kan aangewys word om swanger vroue beter in te lig oor die doel en belangrikheid daarvan om hierdie supplemente te neem.
Ordonez, Gavilanez Sandra. "Nutritional and health behavior of the indigenous pregnant women in the community of Tunshi-San Nicolas, Chimborazo Province." BYU ScholarsArchive, 1999. https://scholarsarchive.byu.edu/etd/5410.
Full textDe, La Torre Mary McCarter. "Maternal anthropometric measures and nutrient intake during the second trimester of pregnancy of normal weight and overweight gravidas." Thesis, Virginia Tech, 1985. http://hdl.handle.net/10919/45644.
Full textMaster of Science
Tshitaudzi, Gilbert Tshimangadzo. "Nutritional status of pregnant women (under 20 years of age) with special emphasis on iron and folic acid status." Thesis, Stellenbosch : Stellenbosch University, 2003. http://hdl.handle.net/10019.1/53529.
Full textENGLISH ABSTRACT: Pregnancy and growth have been found to have a detrimental effect on the micronutrient status of adolescent girls. Dietary studies in adolescents have shown serious shortfalls in their dietary iron and folate intake. The competition for nutrients between the fetus and a pregnant adolescent may carry the risk of complications such as intrauterine growth retardation, pre-eclampsia, both maternal and fetal intrapartum mortality, the increased risk of birth injuries and low birth weight. The aim of the study was to assess the nutritional status of rural black, pregnant teenagers attending the antenatal clinic at Siloam Hospital in the Limpopo Province, with special emphasis on iron and folic acid intake, and evaluation of the newborn babies in terms of weight status and neural tube defects. The nutritional status was determined in 40 pregnant and 40 non-pregnant adolescent girls. The pregnant girls were selected during their first visit to the antenatal clinic, and the non-pregnant girls were selected from nearby schools. The demographic and dietary history questionnaires were used to collect information from the subjects. The dietary intake of the subjects was collected by the completion of a pre-tested quantified food frequency questionnaire. The anthropometric questionnaire was used to get information from the pregnant adolescents and the control group. The infant anthropometric measurements questionnaire provided information on the infant and the outcome of birth. Blood was collected from the pregnant adolescent girls and the control subjects. Anaemia was observed in 57.5% of the pregnant and 27.5% of the non-pregnant adolescents (haemoglobin
Malta, Maíra Barreto [UNESP]. "Promoção da caminhada no lazer e alimentação saudável na atenção pré-natal: estudo de intervenção controlado." Universidade Estadual Paulista (UNESP), 2015. http://hdl.handle.net/11449/139304.
Full textFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Objetivo: delinear, implementar e avaliar a efetividade de uma intervenção - inserção sistematizada da promoção da alimentação saudável e caminhada no lazer na atenção pré-natal rotineira realizada por médicos e enfermeiros em unidades de saúde da família - sobre cinco práticas alimentares e a realização de caminhada no lazer por gestantes. Métodos: estudo de intervenção controlado, não randomizado, no qual participaram 42 médicos/enfermeiros e uma amostra (n=353) de gestantes por eles assistidas em unidades de atenção primária à saúde da rede pública do município de Botucatu-SP, Brasil. O estudo foi dividido em duas etapas: avaliação das mudanças em conhecimentos e práticas dos profissionais e avaliação do impacto da intervenção sobre os comportamentos das gestantes por eles assistidas. Na primeira, foi delineada e implementada uma ação educativa (AE), com 16 horas, presenciais, dirigida a médicos e enfermeiros que assistem gestantes em 9 unidades de saúde da família, com o objetivo de ampliar/adequar seus conhecimentos sobre alimentação e atividade física na gestação e organizar o processo de trabalho para a inserção sistematizada no pré-natal da promoção de 5 práticas alimentares (3 frutas diariamente; 2 porções de hortaliças e 2 de feijão, pelo menos em 5 dias da semana; consumo esporádico (no máximo uma vez por semana) de refrigerante e/ou biscoito industrializado) e da orientação das gestantes para a realização de caminhada no lazer. A AE incluiu um curso de imersão (8hs) com todos os profissionais e 3 oficinas de trabalho em cada unidade de saúde. Os conhecimentos e práticas dos participantes (n=22), antes e após a intervenção, foram comparados aos de um grupo controle (n=20), formado pelos profissionais de 8 unidades básicas de saúde de modelo tradicional (UBS) situadas no mesmo município e que não foram envolvidas na intervenção. Nos dois grupos, os conhecimentos...
Objective: to design, implement and evaluate the effectiveness of an intervention - systematic insertion of promoting healthy eating and leisure-time walking during in routine prenatal care performed by doctors and nurses in family health care units - over five dietary practices and the realization of leisure-time walking at by pregnant women. Methods: this is a controlled intervention study, not randomized, in which took part 42 doctors/nurses and a sample (n=353) of pregnant women attended by those professionals in primary health care settings to public health care in the city of Botucatu-SP, Brazil. The study has been divided into two stages. The first one was the implementation and evaluation of an educational activity (EA), with 16 hours, by attendance, addressed to doctors and nurses who assist pregnant women in nine family health care units, in order to extend/adapt their knowledge of nutrition and physical activity during pregnancy and then introduce routinely and systematically in prenatal care the promotion of 5 dietary practices (3 fruit daily; 2 servings of vegetables and two servings of beans, at least 5 days a week; sporadic consumption (maximum once a week) of soda and / or industrialized cookie), and guidance of pregnant women to walking during leisure time. The knowledge and practices of the participants (n=22) before and after the EA, have been compared to a control group (n=20), formed by professionals of eight traditional health care units not involved in the educational activity. This knowledge has been evaluated in both groups with a self-applied questionnaire, elaborated for this research; practices (guidance for leisure-time walking and healthy eating) have been measured by interviews with pregnant women assisted by two professional groups, in their homes. We have generated two scores of knowledge (about walking and nutrition) and we have used ANOVA for repeated measures to assess changes before and after the ...
Malta, Maíra Barreto. "Promoção da caminhada no lazer e alimentação saudável na atenção pré-natal : estudo de intervenção controlado /." Botucatu, 2015. http://hdl.handle.net/11449/139304.
Full textCoorientador: Maria Helena D'Aquino Benício
Banca: Daniela Saes Sartorelli
Banca: Luiza Cristina Godim Domingues Dias
Banca: Paula Andrea Martins
Banca: Silvia Justina Papini
Resumo: Objetivo: delinear, implementar e avaliar a efetividade de uma intervenção - inserção sistematizada da promoção da alimentação saudável e caminhada no lazer na atenção pré-natal rotineira realizada por médicos e enfermeiros em unidades de saúde da família - sobre cinco práticas alimentares e a realização de caminhada no lazer por gestantes. Métodos: estudo de intervenção controlado, não randomizado, no qual participaram 42 médicos/enfermeiros e uma amostra (n=353) de gestantes por eles assistidas em unidades de atenção primária à saúde da rede pública do município de Botucatu-SP, Brasil. O estudo foi dividido em duas etapas: avaliação das mudanças em conhecimentos e práticas dos profissionais e avaliação do impacto da intervenção sobre os comportamentos das gestantes por eles assistidas. Na primeira, foi delineada e implementada uma ação educativa (AE), com 16 horas, presenciais, dirigida a médicos e enfermeiros que assistem gestantes em 9 unidades de saúde da família, com o objetivo de ampliar/adequar seus conhecimentos sobre alimentação e atividade física na gestação e organizar o processo de trabalho para a inserção sistematizada no pré-natal da promoção de 5 práticas alimentares (3 frutas diariamente; 2 porções de hortaliças e 2 de feijão, pelo menos em 5 dias da semana; consumo esporádico (no máximo uma vez por semana) de refrigerante e/ou biscoito industrializado) e da orientação das gestantes para a realização de caminhada no lazer. A AE incluiu um curso de imersão (8hs) com todos os profissionais e 3 oficinas de trabalho em cada unidade de saúde. Os conhecimentos e práticas dos participantes (n=22), antes e após a intervenção, foram comparados aos de um grupo controle (n=20), formado pelos profissionais de 8 unidades básicas de saúde de modelo tradicional (UBS) situadas no mesmo município e que não foram envolvidas na intervenção. Nos dois grupos, os conhecimentos...
Abstract: Objective: to design, implement and evaluate the effectiveness of an intervention - systematic insertion of promoting healthy eating and leisure-time walking during in routine prenatal care performed by doctors and nurses in family health care units - over five dietary practices and the realization of leisure-time walking at by pregnant women. Methods: this is a controlled intervention study, not randomized, in which took part 42 doctors/nurses and a sample (n=353) of pregnant women attended by those professionals in primary health care settings to public health care in the city of Botucatu-SP, Brazil. The study has been divided into two stages. The first one was the implementation and evaluation of an educational activity (EA), with 16 hours, by attendance, addressed to doctors and nurses who assist pregnant women in nine family health care units, in order to extend/adapt their knowledge of nutrition and physical activity during pregnancy and then introduce routinely and systematically in prenatal care the promotion of 5 dietary practices (3 fruit daily; 2 servings of vegetables and two servings of beans, at least 5 days a week; sporadic consumption (maximum once a week) of soda and / or industrialized cookie), and guidance of pregnant women to walking during leisure time. The knowledge and practices of the participants (n=22) before and after the EA, have been compared to a control group (n=20), formed by professionals of eight traditional health care units not involved in the educational activity. This knowledge has been evaluated in both groups with a self-applied questionnaire, elaborated for this research; practices (guidance for leisure-time walking and healthy eating) have been measured by interviews with pregnant women assisted by two professional groups, in their homes. We have generated two scores of knowledge (about walking and nutrition) and we have used ANOVA for repeated measures to assess changes before and after the ...
Doutor
Asente, Rebecca Ann. "The effect of non-weight-bearing exercise and protein intake during pregnancy on maternal and fetal zinc content in the Sprague-Dawley rat." Thesis, Virginia Polytechnic Institute and State University, 1985. http://hdl.handle.net/10919/90906.
Full textM.S.
Edwards, Lisa J. "Maternal undernutrition and fetal blood pressure and the hypothalamo-pituitary adrenal axis in the late gestation fetal sheep." Title page, table of contents and abstract only, 2001. http://web4.library.adelaide.edu.au/theses/09PH/09phe2654.pdf.
Full textMaart, Lana Catherine. "Knowledge, attitudes and practices related to lifestyle factors among childbearing women in the West Coast/Winelands health district." Thesis, University of the Western Cape, 1990. http://etd.uwc.ac.za/index.php?module=etd&action=viewtitle&id=gen8Srv25Nme4_5520_1207815219.
Full textMany of the known risk factors associated with low birth weight, such as socio-economic status, ethnicity, genetic makeup, and obstetric history, are not within a women's immediate control. However, there are many things that a woman can do to improve her chances of having a normal healthy child. Lifestyle behaviours, such as cigarette smoking, nutrition and the use of alcohol, play an important role in determining the growth of the fetus. The aim of this study was to establish the knowledge, attitudes and practices related to lifestyle factors such as alcohol use, smoking and nutrition among childbearing women and health care workers on the farms in Stellenbosch and Vredendal.
Anderson, Susan A. "Maternal dietary glucose intake affects neonatal gastrointestinal development in rats." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape9/PQDD_0029/MQ50707.pdf.
Full textWhitmore, Erika. "Influence of maternal diet on the developmental profile of postnatal glucose transporters." Thesis, McGill University, 1998. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=21664.
Full textComstock, Sarah Michelle. "Examining the Effect of Maternal High-Fat Diet Consumption on the Physiology and Pancreas Development of Fetal and Juvenile Nonhuman Primate Offspring." PDXScholar, 2012. https://pdxscholar.library.pdx.edu/open_access_etds/551.
Full textCameron, Sharon Ruth. "Effects of exercise and protein nutriture on the iron status of rats at selected intervals of gestation." Thesis, Virginia Polytechnic Institute and State University, 1985. http://hdl.handle.net/10919/104302.
Full textNicaragua, Odila. "Design and application of a nutrition education program based on a test of improved practices for pregnant women and women of childbearing age in La Rinconada and Cuambo." BYU ScholarsArchive, 2003. https://scholarsarchive.byu.edu/etd/5407.
Full textSteele, Mary. "Development of a theory and evidence informed intervention to promote smoking cessation during pregnancy using narrative, text-messages and images as modes of delivery." Thesis, University of Stirling, 2015. http://hdl.handle.net/1893/22064.
Full textFowler, Rebecca. "Grand Canyons: Authoritative Knowledge and Patient-Provider Connection." Thesis, University of North Texas, 2015. https://digital.library.unt.edu/ark:/67531/metadc799543/.
Full textDoi, Lawrence K. "Screening and alcohol brief interventions in antenatal care : a realistic evaluation." Thesis, University of Stirling, 2012. http://hdl.handle.net/1893/9513.
Full textLippert, M. "Aspects of feeding the hill ewe during pregnancy." Thesis, University of Edinburgh, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.354201.
Full textFlanders, Lisa S. "Nutritional knowledge and infant feeding decisions of pregnant women." Virtual Press, 1998. http://liblink.bsu.edu/uhtbin/catkey/1115735.
Full textDepartment of Family and Consumer Sciences
Viljoen, Estelle. "A systematic review of the effect and safety of ginger in the treatment of pregnancy-associated nausea and vomiting." Thesis, Stellenbosch : Stellenbosch University, 2012. http://hdl.handle.net/10019.1/20265.
Full textENGLISH ABSTRACT: Background: Nausea and vomiting during pregnancy (NVP) is a common medical condition. Due to possible harmful side-effects that conventional medicine may pose to the fetus, many mothers choose not to use it, and are left helpless against NVP. There is a need for alternative treatment to relieve NVP symptoms. Objectives: This systematic review (SR) investigated current evidence regarding ginger for the treatment of NVP. The primary objective was to assess the effectiveness of ginger in treating NVP. The secondary objective was to assess the safety of ginger during pregnancy, by identifying adverse events or side-effects. Search strategy: Electronic search of bibliographic databases (1966-February 2011). Selection criteria: Randomized controlled trials (RCTs) of the efficacy of ginger by any route, as treatment for NVP in pregnant women regardless of their age or stage of pregnancy. Data collection and analysis: The principal investigator and independent reviewer individually identified relevant studies, extracted data and assessed trial quality. Data analysis was performed using the RevMan5 software. Differences at the level of p<0.05 were considered to be statistically significant. Results: Eleven RCTs involving 1176 pregnant women were included. The quality of evidence was low, hence the high risk of bias and imprecision of results. Ginger significantly improved the symptoms of nausea when compared to placebo, when comparing the results of this SR to past SRs, and taking into account a meta-analysis performed on two relatively large included studies (mean difference (MD) 1.20, 95% confidence interval (CI) 0.56-1.84, p=0.0002, I2=0%). However, another meta-analysis on two smaller studies indicated no significant improvement in nausea. Ginger did not significantly improve nausea when compared to vitamin B6 (MD 0.34, 95% CI -1.52-2.20, p=0.7, I2=91%). Similarly, ginger did not significantly reduce the number of vomiting episodes during NVP, when compared to placebo, although there was a trend towards improvement (MD 0.72, 95% CI -0.03-1.46, p=0.06, I2=71%). Subgroup analyses performed seemed to favor the lower daily dosage of <1500mg ginger to possibly be more effective for the relief of nausea. Ginger did not pose a significant risk for spontaneous abortion when compared to placebo (RR 3.14, 95% CI 0.65-15.11, p=0.15; I2=0%), or to vitamin B6 (RR 0.49, 95% CI 0.17-1.42, p=0.19, I2=40%). Similarly, ginger did not pose a significant risk for the side effects of heartburn or drowsiness when compared to placebo or vitamin B6. When compared to dimenhydrinate, ginger posed a smaller risk for drowsiness (RR 0.08, 95% CI 0.03-0.18) and no increased risk for heartburn. Conclusions: This review suggests potential benefits of ginger in reducing nausea symptoms in pregnancy (bearing in mind the limited number of studies, variable outcome reporting and quality of evidence). Ginger did not have a significant impact on vomiting episodes, nor pose a risk for side effects or adverse events during pregnancy. Based on evidence from this SR, ginger could be considered a harmless and possibly effective alternative option for women suffering from the symptoms of NVP. Large RCTs are necessary to confirm the possible benefit of ginger as treatment for NVP.
AFRIKAANSE OPSOMMING: Agtergrond: Naarheid en vomering tydens swangerskap (NVS) is ‘n algemene mediese toestand. As gevolg van moontlike skadelike newe-effekte wat konvensionele medikasie kan veroorsaak vir die fetus, vermy baie moeders dit en word hulpeloos gelaat teen NVS. Dus is daar behoefte aan alternatiewe behandeling vir NVS. Doelwitte: Hierdie sistematiese literatuuroorsig (SO) het huidige literatuur ondersoek wat verband hou met gemmer vir behandeling van NVS. Die primêre doelwit was om effektiwiteit van gemmer as behandeling vir NVS te assesseer. Die sekondêre doelwit was om veiligheid van gemmer tydens swangerskap te assesseer, deur ongunstige gebeure en newe-effekte te identifiseer. Soektogstrategie: Elektroniese soektog van bibliografiese databasisse (1966-Februarie 2011). Seleksiekriteria: Verewekansigde gekontrolleerde proewe (RCTs) van gemmer deur enige roete as behandeling van NVS, in swanger vroue ongeag ouderdom of stadium van swangerskap. Dataversameling en –analise: Die hoof navorser en ‘n onafhanklike hersiener het individueel relevante studies geidentifiseer, data ekstraksie onderneem en studie-kwaliteit geassesseer. Data-analise is uitgevoer deur die RevMan5 sagteware te gebruik. Verskille by die vlak van p<0.05 was beskou as statisties betekenisvol. Hoof resultate: Elf RCTs waarby 1176 swanger vroue betrokke was, is ingesluit. Die studie-kwaliteit was swak, dus die hoë risiko vir sydigheid en onakkuraatheid van resultate. Gemmer het beduidend die simptome van naarheid verbeter in vergelyking met plasebo, wanneer die resultate van hierdie SO met vorige SO’s vergelyk word, en die meta-analise in ag geneem word wat op twee relatiewe groot ingeslote studies uitgevoer is (gemiddelde verskil (MD) 1.20, 95% vertrouens interval (VI) 0.56-1.84, p=0.0002,I2=0%). Kontrasterend, het ‘n ander meta-analise van twee kleiner studies geen beduidende verbetering in naarheid aangedui nie. Gemmer het nie beduidend naarheid verbeter wanneer dit met vitamien B6 vergelyk word nie (MD 0.34, 95% VI -1.52-2.20, p=0.7, I2=91%). Soortgelyk, het gemmer nie die aantal vomerings-episodes verminder, in verglyking met plasebo nie, maar daar was wel ‘n neiging na verbetering (MD 0.72, 95% VI -0.03-1.46, p=0.06, I2=71%). Die subgroup-analise blyk ten gunste te wees van die laer daaglikse dosis van <1500mg gemmer om meer effektief te wees vir die behandeling van naarheid. Gemmer het nie ‘n beduidende risiko ingehou vir spontane aborsie, wanneer dit vergelyk word met plasebo (relatiewe risiko (RR) 3.14, 95% VI 0.65-15.11,p=0.15;I2=0%), of vitamien B6 nie (RR 0.49, 95% VI 0.17-1.42,p=0.19;I2=40%). Soortgelyk, het gemmer nie ‘n beduidende risiko ingehou vir newe-effekte van sooibrand of duiseligheid, wanneer dit vergelyk word met plasebo of vitamien B6 nie. Wanneer dit vergelyk word met dimenhidrinaat, het gemmer ‘n kleiner risiko ingehou vir duiseligheid (RR 0.08, 95% VI 0.03-0.18) en geen verhoogde risiko vir sooibrand nie. Gevolgtrekkings: Hierdie SO dui ‘n potensiële voordeel van gemmer aan in vermindering van naarheid tydens swangerskap (inagnemend van die klein hoeveelheid studies, wisselende uitkomste-rapportering en studie-kwaliteit). Gemmer het nie ‘n beduidnede impak gehad op vomerings-episodes nie, en ook nie ‘n risiko ingehou vir newe-efekte of ongunstige gebeure tydens swangerskap nie. Volgens bewyse uit hierdie SO, kan gemmer beskou word as ‘n skadelose en moontlike effektiewe alternatiewe opsie vir vroue wat lei aan NVP. Grootskaalse RCTs is nodig om die moontlike voordeel van gemmer as behandeling vir NVS te bevestig.
Cruz, Bread Leandro Gomes da 1979. "Metabolismo proteico e estresse oxidativo em musculatura de fetos provenientes de ratas portadoras de tumor submetidas a dieta rica em leucina." [s.n.], 2007. http://repositorio.unicamp.br/jspui/handle/REPOSIP/314502.
Full textDissertação (mestrado) - Universidade Estadual de Campinas, Instituto de Biologia
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Resumo: Câncer acomete, aproximadamente, uma entre 3000 gravidezes e causa um terço de mortes maternas. A leucina é usada experimentalmente para minimizar as alterações do metabolismo protéico durante o crescimento tumoral. Este trabalho investigou os efeitos do crescimento tumoral sobre o metabolismo protéico e estresse oxidativo nos fetos provenientes de ratas alimentadas com dieta suplementada com leucina. Os grupos de fêmeas prenhes foram divididos da seguinte forma: controle (C), controle com dieta suplementada com leucina (L), tumor (W), tumor com dieta suplementada com leucina (WL), dieta pareada á ingestão diária das ratas do grupo W (Cp), dieta suplementada com leucina e pareada á ingestão diária das ratas do grupo WL (Lp). Após 20 dias de prenhes os músculos fetais foram analisados. Os resultados mostraram que a síntese protéica fetal foi reduzida no grupo W quando comparados aos outros grupos. Houve significativa recuperação da síntese protéica no músculo dos fetos WL sugerindo efeito positivo do uso de aminoácido de cadeia ramificada nessa situação. Ocorreu aumento significativo da degradação protéica nos fetos W. Essa perda protéica foi amenizada pelo uso da dieta suplementada com leucina indicando efeito benéfico sobre a degradação protéica no grupo WL que obteve valores similares ao observado no grupo C. A atividade da enzima glutationa-S-transferase ficou elevada no músculo de fetos WL em comparação com o grupo W. Também houve aumento na atividade da enzima fosfatase alcalina no grupo WL indicando maior atividade celular nesse grupo quando comparado ao grupo W. A presença de MDA (Malondialdeído) no músculo fetal também ficou reduzida nos fetos WL. Com a análise desses parâmetros conclui-se que a dieta suplementada com leucina pode alterar o metabolismo muscular fetal aumentando a síntese protéica e reduzindo o efeito danoso do estresse oxidativo.
Abstract: Cancer occurs in approximately 1 per 3.000 pregnancies and accounts for one-third of maternal deaths. Leucine has been used experimentally to minimize the protein metabolism changes during tumor growth. The present work investigated the effects of tumor growth on muscle protein metabolism and oxidative stress in fetus pregnant rats fed a leucine-rich diet. Fetal groups from pregnant Wistar rats were: control (C), control fed leucine-rich diet (L), tumor-bearing (W), tumor-bearing fed leucine-rich diet (WL), Pair-fed control (P) and Pair-fed Leucine (PL). After 20 days the fetal muscles were analyzed. The results showed that fetal protein synthesis was decreased in W group, when compared to the other groups. The significantly recover on muscle protein synthesis in fetus of WL group suggested a positive effect of this branched-chain amino acid. There was a significant increase on protein degradation in W fetus and a protective effect of the leucine-rich diet on muscle protein waste in WL group, since it was similar to C group. The muscle enzyme glutathione-S-transferase activity was increased in WL fetus in comparison to W group. The muscle alkaline phosphatase activity increased in WL group. The malondialdehyde content (MDA) in fetal muscle was decreased in WL fetus. The leucine supplemented diet can alter the fetal muscle protein metabolism, improving the fetal muscle protein synthesis and reducing the oxidative stress.
Mestrado
Fisiologia
Mestre em Biologia Funcional e Molecular
Reis, Lilian Barros de Sousa Moreira [UNESP]. "Perfil nutricional materno relacionado a marcadores da síndrome metabólica e do controle glicêmico no diabete melito gestacional." Universidade Estadual Paulista (UNESP), 2011. http://hdl.handle.net/11449/99240.
Full textFundação de Ensino e Pesquisa em Ciências da Saúde (FEPECS)
A nutrição adequada é importante na gestação e, sobretudo, naquelas complicadas pelo diabete. Avaliar o consumo alimentar, pelo Índice de Qualidade de Dieta (IQD), em gestantes portadoras de Diabetes Melito Gestacional (DMG), referenciadas para o serviço especializado. Estudo transversal e descritivo em 65 gestantes portadoras de DMG, após a 20ª semana. O consumo alimentar foi quantifi cado pelo VET R24h, e pelo VET QFA, e qualifi cado pelo IQD, proposto por Fisberg et al. (2004), adaptado para a população de gestantes diabéticas. 67,7% das gestantes apresentavam IMC pré-gestacional ≥ 25 kg/m2. O valor calórico observado no R24h foi de 1657 ± 532 kcal. De acordo com o IQD, a dieta foi adequada em 51,6% das gestantes. Os componentes de pior pontuação foram os vegetais e os produtos lácteos. A ingestão de carnes, sódio e gordura total receberam as maiores pontuações. O IQD, referenciado pelo R24h e aplicado como instrumento de avaliação nutricional, evidenciou que a dieta foi considerada inadequada ou com necessidade de adequação em metade da população de gestantes avaliadas. Estas inadequações foram relacionadas à baixa ingestão de verduras e legumes e de leite e produtos lácteos. Tais resultados indicam a necessidade de priorizar ações educativas no pré-natal, para incentivar o consumo de vegetais e produtos lácteos entre essas gestantes, portadoras de DMG
To proper nutrition is important during pregnancy and especially in those complicated by diabestes. Evaluating food intake, the Indicators of Diet Quality (IDQ), in pregnant women with GDM, referenced to the specialist service. Descriptive cross-sectional study in 65 pregnant women with Gestacinal Diadetes Mellitus (GDM) after 20 weeks. Food intake was measured by R24h VET and the FFQ, and qualifi ed IDQ proposed by Fisberg et al. (2004), adapted for the population of diabetic women. 67.7% of the women had pré-pregnancy BMI ≥ 25 kg/m2 . The caloric value was observed in 24-hour recall of 1657 ± 532 kcal. According to IDQ, the diet was adequate in 51.6% of pregnant women. The components were the worst score vegetables and dairy products. The intake of meat, total fat and sodium received the highest scores. IDQ, referenced by 24-hour recall and applied as a tool for nutritional assessment showed that the diet was considered inappropriate or in need of adjustment in half of the pregnant population evaluated. These inadequacies were related to low intake of vegetables and milk and dairy products. These results indicate the need to prioritize educational activities in prenatal care, to encourage consumption of vegetables and dairy products from these pregnant women, suffering from DMG
Reis, Lilian Barros de Sousa Moreira. "Perfil nutricional materno relacionado a marcadores da síndrome metabólica e do controle glicêmico no diabete melito gestacional /." Botucatu : [s.n.], 2011. http://hdl.handle.net/11449/99240.
Full textCoorientador: Adriana Pederneiras Rebelo da Silva
Banca: Simone Gonçalves de Almeida
Banca: Belmiro Gonçalves Pereira
Resumo: A nutrição adequada é importante na gestação e, sobretudo, naquelas complicadas pelo diabete. Avaliar o consumo alimentar, pelo Índice de Qualidade de Dieta (IQD), em gestantes portadoras de Diabetes Melito Gestacional (DMG), referenciadas para o serviço especializado. Estudo transversal e descritivo em 65 gestantes portadoras de DMG, após a 20ª semana. O consumo alimentar foi quantifi cado pelo VET R24h, e pelo VET QFA, e qualifi cado pelo IQD, proposto por Fisberg et al. (2004), adaptado para a população de gestantes diabéticas. 67,7% das gestantes apresentavam IMC pré-gestacional ≥ 25 kg/m2. O valor calórico observado no R24h foi de 1657 ± 532 kcal. De acordo com o IQD, a dieta foi adequada em 51,6% das gestantes. Os componentes de pior pontuação foram os vegetais e os produtos lácteos. A ingestão de carnes, sódio e gordura total receberam as maiores pontuações. O IQD, referenciado pelo R24h e aplicado como instrumento de avaliação nutricional, evidenciou que a dieta foi considerada inadequada ou com necessidade de adequação em metade da população de gestantes avaliadas. Estas inadequações foram relacionadas à baixa ingestão de verduras e legumes e de leite e produtos lácteos. Tais resultados indicam a necessidade de priorizar ações educativas no pré-natal, para incentivar o consumo de vegetais e produtos lácteos entre essas gestantes, portadoras de DMG
Abstract: To proper nutrition is important during pregnancy and especially in those complicated by diabestes. Evaluating food intake, the Indicators of Diet Quality (IDQ), in pregnant women with GDM, referenced to the specialist service. Descriptive cross-sectional study in 65 pregnant women with Gestacinal Diadetes Mellitus (GDM) after 20 weeks. Food intake was measured by R24h VET and the FFQ, and qualifi ed IDQ proposed by Fisberg et al. (2004), adapted for the population of diabetic women. 67.7% of the women had pré-pregnancy BMI ≥ 25 kg/m2 . The caloric value was observed in 24-hour recall of 1657 ± 532 kcal. According to IDQ, the diet was adequate in 51.6% of pregnant women. The components were the worst score vegetables and dairy products. The intake of meat, total fat and sodium received the highest scores. IDQ, referenced by 24-hour recall and applied as a tool for nutritional assessment showed that the diet was considered inappropriate or in need of adjustment in half of the pregnant population evaluated. These inadequacies were related to low intake of vegetables and milk and dairy products. These results indicate the need to prioritize educational activities in prenatal care, to encourage consumption of vegetables and dairy products from these pregnant women, suffering from DMG
Mestre
"Maternal serum level of 25(OH)D in Hong Kong Chinese pregnant women and its relationship with pregnancy outcome." 2013. http://library.cuhk.edu.hk/record=b5549764.
Full text共有237名單胎妊娠婦女以及62名多胎妊娠的婦女在2010年8月至2011年11月間參加本研究中的隊列研究,分別在參加研究時(<20 孕周)、24-28孕周、31-36孕周以及産後6-11周進行抽血測量血清25(OH)D以及PTH水平,同時填寫一份包括對每月攝取含維生素D的食物以及營養補充劑頻度、接受日照情況及喜好、以及肌肉不適等情況的問卷,并在24-28孕周進行75克口服葡萄糖耐量試驗。參與隊列研究的單胎孕婦在20周前、31-36孕周以及産後隨訪時接受用定量超聲測量非優勢手的橈骨遠端以及中指近掌指骨的骨質超聲速率(SoS)。在産後複查時,對其嬰兒左側腓骨中部的骨質SoS進行測量。記錄婦女各次檢查時的體重、抽血月份紫外線輻射強度的歷史記錄、以及妊娠結局。另外募集一批孕婦參加病例對照研究,比較患早產(PTB)、子癇前期(PET)、妊娠糖尿病 (GDM)以及胎兒生長受限(FGR)併發癥的婦女與對照組 (體重指數以及抽血時紫外線強度配對)的血清25(OH)D水平。
孕婦在孕期的平均25(OH)D水平在44.7 ± 12.6 至48.9 ± 17.1 nmol/l範圍,25(OH)D水平與體重指數、維生素D營養補充劑、抽血時紫外線強度以及個人對陽光的喜好情況有關,而與胎兒數量、孕次、孕周以及終止妊娠無關。
單胎妊娠的孕婦三個孕期的血清25(OH)D與PTH水平均負相關,但在多胎妊娠中,二者無明顯相關性。PTH在孕期以及産後的變化相對不受25(OH)D影響。孕婦25(OH)D的水平與孕婦肌肉酸痛癥狀、産後恢復、孕期及產褥期骨質流失以及嬰兒骨質無關。患早期PTB(< 34孕周)、PET或FGR的孕婦的血清25(OH)D比對照組低,但GDM患者的25(OH)D水平與對照組無差別。血清25(OH)D低於34.3 nmol/l者的早期早產以及子癇前期的風險增高,低於50 nmol/l者發生胎兒生長受限的風險增高。服用維生素D補充劑情況可能影響25(OH)D與FGR的關係。
總而言之,血清25(OH)D水平不足以全面完全反映孕期維生素D的情況,對預測不良妊娠結局的作用有限。
This prospective study explored the maternal serum level of 25(OH)D in Chinese pregnant women in Hong Kong and the factors affecting 25(OH)D level. It also explored the correlation between maternal 25(OH)D with PTH level, maternal musculoskeletal complaints, adverse pregnancy outcome, maternal bone turnover during pregnancy and postpartum, and the bone development of the offspring, aiming to explore and establish a normal range of 25(OH)D level in pregnancy for the Hong Kong Chinese women.
A total of 237 women with singleton pregnancy and 62 women with multiple pregnancies were recruited for the cohort study from August, 2010 to November, 2011. Maternal blood samplings for 25(OH)D and PTH measurements were performed at recruitment, 24-28 weeks, 31-36 weeks of gestation, and 6-11 weeks postpartum respectively. A questionnaire which included the monthly dietary and supplement intake of vitamin D, questions about sunlight exposure, and musculoskeletal complaints was administered on each visit. A 75g oral glucose tolerance test (OGTT) was performed on cohort cases at 24-28 weeks of gestation. Measurements of the speed of sound (SoS) at the distal one third of the maternal radius and the proximal phalanx of the third finger of the non-dominant side were performed with quantitative ultrasonography (QUS) measurement during the visits at the first and third trimesters, and postnatal period. The SoS at the left mid-shaft tibia of the offspring was determined during the postnatal visit. Maternal characteristics, ultraviolet radiation (UVR) intensity at blood sampling, and pregnancy outcome, were also recorded. Cases with pregnancy complications were recruited for case-control studies, and maternal 25(OH)D level was examined with respect to preterm birth (PTB), preeclampsia (PET), gestational diabetes (GDM), and fetal growth restriction (FGR, birthweight below the 10th percentile of the customized estimated birthweight). The controls were matched for booking body mass index (BMI) and UVR intensity at blood sampling.
The mean 25(OH)D level in ranged from 44.7 ± 12.6 to 48.9 ± 17.1 nmol/l in the three trimesters, and was related to BMI, vitamin D supplementation, UVR intensity at blood sampling, and the acceptance of sunlight exposure, but not the number of fetus, parity, gestational age, or the completion of pregnancy.
Inverse correlation between PTH and 25(OH)D were observed in singleton, but not in multiple, pregnancy. The change in maternal PTH level is found to be relatively independent from that of 25(OH)D. There was no correlation between maternal 25(OH)D level with musculoskeletal complaints, postnatal recovery, bone turnover during and after pregnancy, or the bone density of the offspring. Maternal 25(OH)D level was lower in women with early PTB ( < 34 weeks), PET, and FGR, but not for GDM. A maternal 25(OH)D level of lower than 34.3nmol/l and 50 nmol/l was associated with increased risk of early PTB, PET, and FGR respectively. But the correlation between maternal 25(OH)D level with FGR might be affected by supplementation.
In conclusion, serum level of 25(OH)D is insufficient in reflecting maternal vitamin D status and metabolism in pregnancy, and is of limited use in predicting adverse pregnancy outcome.
Detailed summary in vernacular field only.
Detailed summary in vernacular field only.
Detailed summary in vernacular field only.
Detailed summary in vernacular field only.
Detailed summary in vernacular field only.
Hu, Zhiyang.
Thesis (Ph.D.)--Chinese University of Hong Kong, 2013.
Includes bibliographical references (leaves 201-223).
Abstracts and appendixes also in Chinese.
Thesis dedication --- p.i
Acknowledgments --- p.ii
Abstract --- p.v
Abstract (Chinese) --- p.viii
List of Abbreviation --- p.x
Table of contents --- p.xiii
List of Figures --- p.xxii
List of Tables --- p.xxiv
Chapter Chapter 1: --- Literature Review --- p.1
Chapter 1.1 --- The synthesis and metabolism of vitamin D --- p.3
Chapter 1.1.1 --- The synthesis of vitamin D --- p.3
Chapter 1.1.2 --- The metabolism of vitamin D --- p.4
Chapter 1.1.3 --- Vitamin D binding protein --- p.10
Chapter 1.1.4 --- Factors related to 25(OH)D level --- p.11
Chapter 1.2 --- Function of vitamin D --- p.13
Chapter 1.2.1 --- Mechanism of vitamin D function --- p.13
Chapter 1.2.2 --- Classic function --- p.14
Chapter 1.2.3 --- Non-classic function --- p.16
Chapter 1.2.3.1 --- Immune system --- p.17
Chapter 1.2.3.2 --- Cardiovascular system --- p.18
Chapter 1.2.3.3 --- Cell proliferation and differentiation --- p.18
Chapter 1.2.3.4 --- Neurological system --- p.19
Chapter 1.2.3.5 --- Reproductive system --- p.20
Chapter 1.2.3.6 --- Fetal development --- p.21
Chapter 1.3 --- The definition of vitamin D deficiency --- p.21
Chapter 1.4 --- Vitamin D status and pregnancy --- p.24
Chapter 1.4.1 --- Alteration in vitamin D metabolism during pregnancy --- p.24
Chapter 1.4.2 --- Factors affecting maternal serum level of 25(OH)D --- p.25
Chapter 1.4.3 --- Vitamin D and bone resorption during pregnancy and lactation --- p.27
Chapter 1.4.3.1 --- Alteration of calcium metabolism, bone absorption and the role of vitamin D --- p.27
Chapter 1.4.3.2 --- Measurement of bone density in pregnant women and babies --- p.33
Chapter 1.4.4 --- Current studies on maternal vitamin D status and pregnancy outcome --- p.35
Chapter 1.4.4.1 --- Birthweight --- p.35
Chapter 1.4.4.2 --- Infection --- p.37
Chapter 1.4.4.3 --- Preterm delivery --- p.39
Chapter 1.4.4.4 --- Diabetes (DM) and gestational diabetes (GDM) --- p.39
Chapter 1.4.4.5 --- Hypertension and preeclampsia --- p.41
Chapter 1.4.4.6 --- Multiple pregnancy, muscular symptoms --- p.42
Chapter 1.4.4.7 --- Vitamin D supplementation and pregnancy outcome --- p.44
Chapter 1.5 --- Defining vitamin D deficiency in pregnancy --- p.45
Chapter 1.6 --- Objective of the study --- p.46
Chapter Chapter 2: --- Study design and methods --- p.48
Chapter 2.1 --- Case recruitment and study design --- p.48
Chapter 2.1.1 --- Longitudinal singleton study --- p.49
Chapter 2.1.2 --- Cross-sectional study --- p.50
Chapter 2.1.2.1 --- Preterm birth (PTB) --- p.51
Chapter 2.1.2.2 --- Preeclampsia (PET) --- p.51
Chapter 2.1.2.3 --- Gestational diabetes (GDM) --- p.52
Chapter 2.1.3 --- Multiple pregnancy study --- p.52
Chapter 2.2 --- Measurements --- p.53
Chapter 2.2.1 --- Hormonal analysis of serum levels of 25(OH)D and PTH --- p.53
Chapter 2.2.2 --- Calculation of monthly intake of vitamin D from diet --- p.55
Chapter 2.2.3 --- SoS measurements --- p.56
Chapter 2.2.4 --- Ultraviolet radiation strength assessment --- p.59
Chapter 2.3 --- Statistical analysis --- p.60
Chapter Chapter 3 --- Longitudinal Study on the Level of and Factors Affecting Vitamin D in Singleton Pregnancy --- p.62
Chapter 3.1 --- Introduction --- p.62
Chapter 3.2 --- Material and method --- p.63
Chapter 3.3 --- Statistics --- p.64
Chapter 3.4 --- Results --- p.65
Chapter 3.4.1 --- Demographic data of the subjects --- p.65
Chapter 3.4.2 --- Maternal levels of 25(OH)D and PTH, and the factors affecting their levels --- p.66
Chapter 3.4.2.1 --- Distribution of 25(OH)D level and PTH level in the four visits --- p.66
Chapter 3.4.2.2 --- Dietary intake of vitamin D and supplementation --- p.69
Chapter 3.4.2.3 --- Seasonality and sunlight exposure --- p.73
Chapter 3.4.2.4 --- Parity --- p.76
Chapter 3.4.3 --- Changes of maternal levels of 25(OH)D and PTH in pregnancy --- p.78
Chapter 3.4.4 --- Independent factors related to maternal 25(OH)D level in pregnancy --- p.79
Chapter 3.4.5 --- Maternal and fetal 25(OH)D level at delivery --- p.80
Chapter 3.4.6 --- Muscular symptoms and other complaints in pregnancy, pregnancy outcome, and their relationships with maternal 25(OH)D level --- p.81
Chapter 3.4.7 --- Postnatal recovery and factors related to postnatal level of 25(OH)D and PTH --- p.86
Chapter 3.4.7.1 --- Postnatal symptoms and relationship with 25(OH)D and PTH --- p.86
Chapter 3.4.7.2 --- The postnatal level of 25(OH)D and PTH in women with different feeding mode --- p.88
Chapter 3.4.7.3 --- Independent factors related to postnatal 25(OH)D and PTH level --- p.89
Chapter 3.4.7.4 --- Factors related to the change of 25(OH)D and PTH after delivery --- p.90
Chapter 3.4.8 --- Correlation between 25(OH)D with PTH in pregnancy and postnatal period --- p.91
Chapter 3.5 --- Discussion --- p.92
Chapter 3.5.1 --- 25(OH)D level in Chinese pregnant women --- p.92
Chapter 3.5.2 --- Factors related to maternal 25(OH)D level --- p.93
Chapter 3.5.2.1 --- Dietary and supplementation --- p.93
Chapter 3.5.2.2 --- Seasonality and outdoor activity --- p.96
Chapter 3.5.2.3 --- Gestational age --- p.98
Chapter 3.5.2.4 --- Age and parity --- p.98
Chapter 3.5.3 --- Relationship of 25(OH)D level in the cord blood with maternal 25(OH)D level --- p.99
Chapter 3.5.4 --- 25(OH)D level and muscular complains in pregnancy --- p.100
Chapter 3.5.5. --- Postnatal recovery and 25(OH)D level --- p.101
Chapter 3.5.6 --- PTH level in pregnancy and postnatal period --- p.101
Chapter 3.6 --- Conclusion --- p.102
Chapter Chapter 4 --- Longitudinal Study on the Relationship between Maternal 25(OH)D level with Changes of Maternal Bone Density in Pregnancy and Lactation, and Factors Affecting Bone Density of newborn Infants --- p.105
Chapter 4.1 --- Introduction --- p.105
Chapter 4.2 --- Material and method --- p.106
Chapter 4.3 --- Statistics --- p.108
Chapter 4.4 --- Results --- p.108
Chapter 4.4.1 --- Demographic data --- p.108
Chapter 4.4.2 --- Maternal bone density and the changes in pregnancy and postnatal recovery --- p.109
Chapter 4.4.2.1 --- Maternal bone density in the first trimester and related factors --- p.109
Chapter 4.4.2.2 --- Maternal bone density in the three visits --- p.109
Chapter 4.4.2.3 --- The change in maternal bone density in the three visits --- p.110
Chapter 4.4.2.4 --- Diversity in the change of bone density in pregnant women --- p.112
Chapter 4.4.3 --- Factors related to the changes in bone density --- p.114
Chapter 4.4.3.1 --- Changes between the first and the third trimesters --- p.114
Chapter 4.4.3.2 --- Change between the third trimester and postnatal visits --- p.116
Chapter 4.4.4 --- The bone density in infants and related factors --- p.120
Chapter 4.5 --- Discussion --- p.122
Chapter 4.5.1 --- Maternal bone density changes in pregnancy and postnatal period --- p.122
Chapter 4.5.2 --- Factors related to the maternal bone density changes in pregnancy and postnatal period --- p.124
Chapter 4.5.2.1 --- Initial bone density, parity, and BMI --- p.125
Chapter 4.5.2.2 --- 25(OH)D and PTH level --- p.126
Chapter 4.5.2.3 --- Supplement --- p.127
Chapter 4.5.2.4 --- Lactation --- p.128
Chapter 4.5.2.5 --- Height --- p.129
Chapter 4.5.3 --- Factors related to bone density of the infant. --- p.130
Chapter 4.5.3.1 --- Maternal 25(OH)D level --- p.130
Chapter 4.5.3.2 --- Gestational age and birthweight --- p.131
Chapter 4.5.3.3 --- Maternal bone density change --- p.131
Chapter 4.5.3.4 --- The gender of the offspring and feeding method --- p.132
Chapter 4.6 --- Conclusion --- p.133
Chapter Chapter 5 --- Maternal 25(OH)D Level in Multiple Pregnancy --- p.134
Chapter 5.1 --- Introduction --- p.134
Chapter 5.2 --- Material and method --- p.135
Chapter 5.3 --- Statistics --- p.136
Chapter 5.4 --- Results --- p.137
Chapter 5.4.1 --- Demographic data of the subjects --- p.137
Chapter 5.4.2 --- The level of 25(OH)D in multiple pregnancy and singleton pregnancy --- p.137
Chapter 5.4.3 --- Supplementation in multiple pregnancy --- p.140
Chapter 5.4.4 --- The change of maternal 25(OH)D and PTH levels in the three trimesters --- p.141
Chapter 5.4.5 --- 25(OH)D level in cord blood and its correlation with 25(OH)D level of the sibling --- p.143
Chapter 5.4.6 --- Correlation between 25(OH) with PTH in pregnancy --- p.143
Chapter 5.5 --- Discussion --- p.144
Chapter 5.5.1 --- 25(OH)D level in multiple pregnancy and singleton pregnancy --- p.144
Chapter 5.5.2 --- Supplementation in multiple pregnancy --- p.146
Chapter 5.5.3 --- Changes of maternal levels of 25(OH)D and PTH in the three trimesters in multiple pregnancy --- p.146
Chapter 5.5.4 --- The PTH/25(OH) correlation --- p.147
Chapter 5.6 --- Conclusion --- p.148
Chapter Chapter 6 --- Maternal level of 25(OH)D in complicated pregnancy --- p.150
Chapter 6.1 --- Introduction --- p.150
Chapter 6.2 --- Method --- p.153
Chapter 6.2.1 --- Preterm birth --- p.155
Chapter 6.2.2 --- Preeclampsia --- p.155
Chapter 6.2.3 --- Gestational diabetes --- p.156
Chapter 6.2.4 --- Fetal growth restriction --- p.157
Chapter 6.2.5 --- The association between 25(OH)D level with pregnancy complication --- p.158
Chapter 6.3 --- Statistics --- p.159
Chapter 6.4 --- Results --- p.160
Chapter 6.4.1 --- Setting of the cutoff values of hypovitaminosis D --- p.160
Chapter 6.4.2 --- Preterm birth --- p.160
Chapter 6.4.3 --- Preeclampsia --- p.164
Chapter 6.4.4 --- Gestational diabetes --- p.168
Chapter 6.4.4.1 --- Case-control study --- p.168
Chapter 6.4.4.2 --- Factors affecting OGTT results --- p.170
Chapter 6.4.5 --- Fetal growth restriction --- p.173
Chapter 6.5 --- Discussion --- p.179
Chapter 6.5.1 --- Adjustment for confounders for case-control study --- p.179
Chapter 6.5.2 --- PTB and 25(OH)D level --- p.181
Chapter 6.5.3 --- PET and 25(OH)D level --- p.182
Chapter 6.5.4 --- GDM and 25(OH)D level --- p.186
Chapter 6.5.5 --- FGR and 25(OH)D level --- p.189
Chapter 6.5.6 --- Defining vitamin D deficiency in pregnancy --- p.192
Chapter 6.6 --- Conclusion --- p.195
Chapter Chapter 7 --- Summary --- p.196
References --- p.201
Chapter Appendix 1 --- Antenatal questionnaire (English/Chinese) --- p.224
Chapter Appendix 2 --- Postnatal questionnaire (English/Chinese) --- p.238
Twenefor, Charlotte. "A food multi-mix supplement for pregnant women in the Vaal Region." Thesis, 2008. http://hdl.handle.net/10352/271.
Full textGood maternal nutrition is vital for the health and survival of the developing foetus. Nutritive inadequacy has been associated with pregnant women in developing countries particularly Sub Saharan Africa. Adequate intake of both macro and micronutrients by this vulnerable group must be ensured to avoid maternal and infant morbidity and mortality. In this study, a novel approach was employed to develop a cost effective, culturally acceptable and nutrient-dense food multi-mix (FMM) supplement that would help meet 20-25 percent of the recommended daily allowance (RDA) of pregnant women aged between 20and 30 years in the Vaal region. Twenty FMM supplements were formulated using South African food composition tables to ensure adequate nutritional content. Two out of the twenty, were selected and named FMM C1 and C3 respectively. FMM C I and C3 was selected owing to their better nutrient contents and affordability when compared with the others. Food items used to formulate FMM C 1 included maize meal, pea powder, peanut dry, milk powder and kidney beans. FMM C3 was formulated with sorghum, maize meal, peanut dry and onion powder. Chosen food items were dried, roasted, ground and mixed together proportionately. FMM supplements (C 1 & C3) were analyzed using standard laboratory techniques to determine their nutrient content. Results obtained were from the Agricultural Research Council (ARC). The shelf life of the FMM supplements was microbiologically tested. Shelf life testing proved safety for the time of consumption, as very little microbiological growth was found in 28 days. The FMM supplements were then incorporated in the development of two acceptable recipes (soup and gravy).Simple recipe leaflets were developed for use by the subjects. The process proved that it is possible to formulate a FMM or any other food product according to certain formulation criteria since formulated FMM supplements (C1 and C3) met the criteria of at least 20% RDA of Protein (g). However, the criteria for micronutrients and energy were difficult to meet as folate iron and energy showed lower percentages of 10%, 14% and 18% respectively in the experimental situation. Sensory evaluation was conducted to ascertain the acceptability of the developed recipes (soup and gravy). The sample consisted of pregnant women randomly selected from John Haynes and Sharpeville clinics respectively, it can be concluded it is possible to formulate and develop products that were culturally acceptable to the consumers (pregnant women) as sensory analysis indicated the majority (85%) of the respondents liked the gravy and 65% liked the soup. Further research is needed to address the impact on nutritional status, long-term compliance and development of range of FMM with various ingredients to determine the most nutritional, cost effective and acceptable product for pregnant women.
Kesa, Hema. "The impact of dietary diversification on the nutritional status of pregnant women in the Vaal Region." Thesis, 2010. http://hdl.handle.net/10352/272.
Full textThe main objective of this study was to develop a cost-effective, culturally acceptable, nutrient-dense food multimix (FMM) based on local food staples for pregnant women in the Vaal region. The impact of the consumption of the multimix on the nutritional status of the women, dietary diversity and outcomes of pregnancy was assessed in an intervention study by measuring the same variables as for a pilot study where the nutritional status of pregnant women was determined. Compliance was measured through monitoring of the FMM consumption and sensory evaluation tests. Quantitative food frequency questionnaires (QFFQs) and 24-hour recall questionnaires were completed in interviews. Anthropometric and biochemical measurements were recorded. The pilot study indicated that the mean total iron intake was 9,74 mg/day, below the estimated average requirement (EAR) of 22 mg/day for pregnant women. Therefore, 41,7 per cent of the women were found to be iron deficient and 50 per cent suffered from iron deficiency anaemia. Food consumed supplied little iron. Eighty per cent of the women were overweight before falling pregnant. Based on the pilot study, the FMM was developed and subjected to the following processes: chemical analysis, shelf life tests, recipe development and sensory evaluation. The product was then implemented in an intervention programme. A control group of pregnant women received soup powder. The respondents were relatively healthy and did not suffer from any chronic diseases. According to the nutrient intakes measured by the QFFQ, indicating usual dietary intakes, the iron intake of 87,5 per cent of the experimental group and 94 per cent of the control group fell below the EAR before intervention. After the intervention it improved in that the iron intake of 35,2 per cent of the experimental group and 33,3 per cent of the control group fell below the EAR. The top 10 items consumed by the experimental group during pre- and post-intervention were mainly rich in carbohydrates. Food containing iron absorption inhibitors such as tannin in tea and phytates in maize meal and bread were among the top 10 foods listed. The highest number of individual food items consumed by an individual in seven days was 39 before the intervention and 52 after the intervention, among the experimental group. The individual food variety improved after the intervention. The reason for this could be the inclusion of the FMM in their diets. The majority of the respondents consumed eight to nine of the nutritious food groups before and after the intervention. The mean food variety score (FVS) for the control group was 38,9 (±10,5) before the intervention, which decreased to 35,8 (±8,39) after the intervention. No improvement in FVS was observed after the intervention in the control group and the FVS indicated medium dietary diversity (30-60 food items). The post-intervention results show that there was an improvement in most of the iron variables. The experimental group showed statistically significant differences between pre- and post-intervention measurements in transferrin and haematocrit levels and the control group in haematocrit levels. All the babies born to the mothers of both the experimental and control groups were healthy with measurements in the normal range. The reason for this could be that the inclusion of the FMM and soup powder in the diets of the experimental and control group, respectively, made the women more aware of the importance of pregnancy monitoring. Furthermore, the attention given to the women by the clinic sisters and the researchers could have contributed to all the improvements mentioned.