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Gimenes, Jessica Cristina, Carolina Ferreira Nicoletti, Marcela Augusta de Souza Pinhel, Bruno Affonso Parenti de Oliveira, Wilson Salgado Júnior, Júlio Sérgio Marchini, and Carla Barbosa Nonino. "Pregnancy After Roux en Y Gastric Bypass: Nutritional and Biochemical Aspects." Obesity Surgery 27, no. 7 (January 19, 2017): 1815–21. http://dx.doi.org/10.1007/s11695-017-2558-0.
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Rizki P, Retno Inten, Rahayu Indriasari, and Baharuddin Bahar. "Exploration of Nutritional Knowledge Aspects of Pregnant Adolescents in Javanese Ethnicity in Ponorogo Regency, East Java." Journal La Medihealtico 1, no. 6 (November 17, 2020): 38–47. http://dx.doi.org/10.37899/journallamedihealtico.v1i6.181.
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Maternal health problems are one of the main indicators of health status, namely maternal mortality. Maternal mortality is still a major public health challenge around the world, including in Indonesia. The purpose of this study was to explore aspects of nutritional knowledge related to healthy food, balanced nutrition, exclusive breastfeeding and care during teenage pregnancy for Javanese ethnicity in Ponorogo, East Java. This type of research is qualitative with a phenomenological approach. This research was conducted in June - July 2020. The main informants in this study were pregnant women aged 10-19 years in the working area of the Balong Community Health Center, Ponorogo Regency. The source of the informants was determined by snowball sampling. The snowball sampling technique is a form of judgment sampling. Data collection is more emphasized through in-depth interviews (in-depth interviews), namely individual dialogue with informants obtained directly from pregnant women. The results of the study of 6 informants who were teenage pregnant women in the Balong PKM work area, Ponorogo Regency, all informants had underweight nutritional status (BMI / age) and Chronic Energy Deficiency (KEK). The knowledge explored in the form of: food for pregnant women, balanced nutrition, exclusive breastfeeding, risk of teenage pregnancy and pregnancy care. Based on the results of the interview, the informant said that foods that are good for pregnant women to consume are fruits, vegetables, milk and vitamins. Regarding balanced nutrition, all informants did not know at all what balanced nutrition for care during pregnancy, the informant said there was no difference in pregnancy care except health checks at health services, treatments such as maintaining cleanliness and regular exercise.
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Loy, See Ling, Rachael Si Xuan Loo, Keith M. Godfrey, Yap-Seng Chong, Lynette Pei-Chi Shek, Kok Hian Tan, Mary Foong-Fong Chong, Jerry Kok Yen Chan, and Fabian Yap. "Chrononutrition during Pregnancy: A Review on Maternal Night-Time Eating." Nutrients 12, no. 9 (September 11, 2020): 2783. http://dx.doi.org/10.3390/nu12092783.
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Evidence from women working night shifts during pregnancy indicates that circadian rhythm disruption has the potential to adversely influence pregnancy outcomes. In the general population, chronodisruption with the potential to affect pregnancy outcomes may also be seen in those with high energy intakes in the evening or at night. However, maternal night eating during pregnancy remains understudied. This narrative review provides an overview of the prevalence, contributing factors, nutritional aspects and health implications of night eating during pregnancy. We derived evidence based on cross-sectional studies and longitudinal cohorts. Overall, night eating is common during pregnancy, with the estimated prevalence in different populations ranging from 15% to 45%. The modern lifestyle and the presence of pregnancy symptoms contribute to night eating during pregnancy, which is likely to coexist and may interact with multiple undesirable lifestyle behaviors. Unfavorable nutritional characteristics associated with night eating have the potential to induce aberrant circadian rhythms in pregnant women, resulting in adverse metabolic and pregnancy outcomes. More research, particularly intervention studies, are needed to provide more definite information on the implications of night eating for mother-offspring health.
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Laurence, M., J. M. Accioly, K. J. Copping, M. P. B. Deland, J. F. Graham, M. L. Hebart, R. M. Herd, et al. "Divergent genotypes for fatness or residual feed intake in Angus cattle. 2. Body composition but not reproduction was affected in first-parity cows on both low and high levels of nutrition." Animal Production Science 58, no. 1 (2018): 43. http://dx.doi.org/10.1071/an13218.
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This paper reports a subset of results from the Beef Cooperative Research Centre-funded Maternal Productivity Project. This research aimed to describe the response of Angus cows of different and divergent genotypes to variable nutritional environments over five breeding seasons. Cows selected for a divergence in either fat depth (HFat vs LFat) or residual feed intake (RFI: HRFI vs LRFI) based on mid-parent estimated breeding values (EBV) for those traits were allocated in replicate groups to either high or low nutritional treatments at two different sites, namely the Vasse Research Centre in Western Australia and the Struan Research Centre in South Australia. The traits reported in this paper include output traits (birth and weaning weight of calves, liveweight change of cows), change traits (change in Rib Fat, P8 fat, eye muscle area and liveweight between specified time points) and reproductive traits [pregnancy rates, percentage calves born alive and days to calving at the days to calving at the second calving opportunity (DC2)]. Having had their first calf, the vulnerability of these young cows to nutritional restriction and how it may adversely affect rebreeding was examined. HFat and HRFI cows were fatter, heavier and had greater eye muscle area than LFat and LRFI, respectively, at all times during the breeding cycle on both levels of nutrition. There was no difference in either days-to-calving or pregnancy rates after the second mating between genotypes. Equally, nutritional treatment had no effect on these traits in this cohort of cows. There was evidence for an implied genetic correlation between Rib Fat EBV, DC2 and pregnancy rates of –0.38 that suggests that selection for leanness may result in reduced fertility of the herd but the effect was not significant herein. As long as producers record the phenotype for both traits and select cows with favourable DC2 as well as low fatness, these problems can be avoided, owing to only 22% of variation in pregnancy rates being explained by DC2 and Rib Fat EBV. Producers can largely be confident that selection for leanness, or increased feed efficiency, has little impact on productivity as long as cows are in adequate body condition to remain healthy and productive.
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Thompson, A. N., M. B. Ferguson, D. J. Gordon, G. A. Kearney, C. M. Oldham, and B. L. Paganoni. "Improving the nutrition of Merino ewes during pregnancy increases the fleece weight and reduces the fibre diameter of their progeny's wool during their lifetime and these effects can be predicted from the ewe's liveweight profile." Animal Production Science 51, no. 9 (2011): 794. http://dx.doi.org/10.1071/an10161.
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Nutrition of ewes during pregnancy can have permanent impacts on the production potential of their progeny. The hypothesis tested in the experiments reported in this paper was that improving the nutrition of Merino ewes during pregnancy and lactation increases the fleece weight and reduces the fibre diameter of their progeny’s wool during their lifetime. In addition, that these effects on the progeny’s wool production can be predicted from the ewe’s liveweight profile. At sites in Victoria and Western Australia in each of 2 years, a wide range in the liveweight and condition score profiles of Merino ewes was generated by varying the amount of supplements fed from joining to Day 100 of pregnancy and the amount of feed on offer grazed from Day 100 to weaning. The site in Victoria was based on perennial pastures and included both single- and twin-bearing ewes whereas the site in Western Australia was based on annual pastures and included single-bearing ewes only. The production and characteristics of wool from the progeny were measured until 51 months of age at the site in Victoria and 33 months of age at the site in Western Australia. The nutritional treatments and the resulting changes in ewe liveweight had significant impacts on the fleece weight and to a lesser extent the fibre diameter of wool produced by their progeny, but there were no consistent effects on other characteristics of progeny fleece wool. The fleece weight of the progeny was related to the liveweight change during pregnancy of their mothers (P < 0.05) and the relationships were similar for the two experiments at each site. At the site in Victoria, a loss of 10 kg in ewe liveweight between joining and Day 100 of pregnancy reduced fleece weight by ~0.2 kg at each shearing until 51 months of age whereas gaining 10 kg from Day 100 of pregnancy to lambing had the opposite effect. The effect of changes in ewe liveweight during late pregnancy on the fleece weight of their progeny at each shearing was of similar magnitude at the site in Western Australia. When evident, the effect of the ewe liveweight profile on the fibre diameter of progeny wool was opposite to the effect on clean fleece weight and the effect of poor nutrition in early to mid pregnancy could be completely overcome by improving nutrition during late pregnancy. Twin-born and reared progeny produced ~0.3 kg less clean wool at each shearing (P < 0.001) that was 0.3-μm broader (P < 0.001) than that from single-born progeny at the site in Victoria. However, the effects of varying ewe nutrition and ewe liveweight change during pregnancy on fleece weight and fibre diameter of progeny wool were similar (P > 0.05) for both single- and twin-born or reared progeny. Overall, these results supported our hypothesis and it is clear that the nutritional management of Merino ewes during pregnancy is important for optimal wool production from their progeny during their lifetime.
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Lemley, C. O., A. M. Meyer, T. L. Neville, D. M. Hallford, L. E. Camacho, K. R. Maddock-Carlin, T. A. Wilmoth, et al. "Dietary selenium and nutritional plane alter specific aspects of maternal endocrine status during pregnancy and lactation." Domestic Animal Endocrinology 46 (January 2014): 1–11. http://dx.doi.org/10.1016/j.domaniend.2013.09.006.
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Maidin, M. Shikh, A. Chadwick, P. C. Khaiseb, P. A. Hawken, and G. B. Martin. "242. Reproductive performance of Australia Cashmere goats supplemented with lupin grain." Reproduction, Fertility and Development 20, no. 9 (2008): 42. http://dx.doi.org/10.1071/srb08abs242.
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The productivity of Cashmere goats depends on their reproductive performance, which, in turn, depends on their level of nutrition. Ovulation rate and pregnancy in sheep are both affected by nutrition, but little is known about the response of female goats (does) to supplementary feeding. The lupin group (n = 40) received 250 g lupin per head per day in addition to pasture whereas the control group (n = 40) received no nutritional supplement. Both groups were synchronised for 17 days with intravaginal progestagen pessaries. The supplement was fed for 21 days, commencing 7 days before the bucks were introduced and intravaginal pessaries were removed (Day –2). Does were expected to ovulate 2 days later on Day 0 and the bucks were removed on Day 3. Blood was sampled for progesterone every 3 days from buck removal (Day 3) until Day 18. Ovulation rate was assessed by trans-rectal ultrasonography on Day 13 and pregnancy was diagnosed by trans-abdominal ultrasonography on Day 61 of the experiment. Does supplemented with lupins had a numerically higher ovulation rate than does fed only on pasture, but this difference was not significant (1.76 ± 3.21 v. 1.52 ± 3.79; P > 0.05). Similarly, there was no difference in the numbers of does conceiving to the first service between the lupin and control group (89% v. 94%; P > 0.05). Progesterone concentrations on Day 12 were higher in does supplemented with lupins than does fed only pasture (6.29 ± 0.27 ng/mL v. 5.41 ± 0.27 ng/mL; lupin and control group; P < 0.05). In conclusion, lupin supplementation induced a numerical increase in ovulation rate but this difference failed to reach significance. Does supplemented with lupins had higher concentrations of progesterone during early pregnancy, which is the opposite effect to that previously reported in sheep.
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Bates, Amy L., Shawn R. McGrath, Maxwell B. Allworth, Susan M. Robertson, and Gordon Refshauge. "A Cross-Sectional Study of Commercial Ewe Management Practices for Different Sheep Breeds across Southern Australia." Animals 13, no. 3 (January 23, 2023): 388. http://dx.doi.org/10.3390/ani13030388.
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The management of ewes across southern Australia may vary with breed and can change over time and, as such, a greater understanding of producer management practices and the motivations that influence these practices is required. A cross-sectional study was performed by telephone interview with sheep producers managing Composite, Maternal, Merino or shedding ewe breeds mated in either spring, summer, or autumn. The surveyed producers were a unique subset of southern Australian producers. A large proportion of the surveyed producers followed current best practice guidelines for ewe mating and lambing nutritional management; however, some producers did not align with these targets. Further, some producers did not see the value in attaining the current recommendations. Pregnancy scanning was widely practiced, likely an artefact of the recruitment process; however, a few producers did not utilize this information for nutritional management at lambing time. Finally, most producers were active in their search for new information, seeking information regularly from a wide range of sources and reported making management changes within the last five years. Further work is required to understand why some producers are not adopting best practice where possible and to understand current barriers for adoption. Management guidelines for all sheep breeds are required to best manage sheep across southern Australia.
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Middleton, Peter G., Elisabeth J. Gade, Cristina Aguilera, Lucy MacKillop, Brenda M. Button, Courtney Coleman, Barbara Johnson, et al. "ERS/TSANZ Task Force Statement on the management of reproduction and pregnancy in women with airways diseases." European Respiratory Journal 55, no. 2 (November 7, 2019): 1901208. http://dx.doi.org/10.1183/13993003.01208-2019.
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This European Respiratory Society/Thoracic Society of Australia and New Zealand statement outlines a review of the literature and expert opinion concerning the management of reproduction and pregnancy in women with airways diseases: asthma, cystic fibrosis (CF) and non-CF bronchiectasis. Many women with these diseases are now living into reproductive age, with some developing moderate-to-severe impairment of lung function in early adulthood. The statement covers aspects of fertility, management during pregnancy, effects of drugs, issues during delivery and the post-partum period, and patients’ views about family planning, pregnancy and parenthood. The statement summarises current knowledge and proposes topics for future research, but does not make specific clinical recommendations.
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Esposito, Pasquale, Giacomo Garibotto, Daniela Picciotto, Francesca Costigliolo, Francesca Viazzi, and Novella Evelina Conti. "Nutritional Challenges in Pregnant Women with Renal Diseases: Relevance to Fetal Outcomes." Nutrients 12, no. 3 (March 24, 2020): 873. http://dx.doi.org/10.3390/nu12030873.
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Pregnancy in women affected by chronic kidney disease (CKD) has become more common in recent years, probably as a consequence of increased CKD prevalence and improvements in the care provided to these patients. Management of this condition requires careful attention since many clinical aspects have to be taken into consideration, including the reciprocal influence of the renal disease and pregnancy, the need for adjustment of the medical treatments and the high risk of maternal and obstetric complications. Nutrition assessment and management is a crucial step in this process, since nutritional status may affect both maternal and fetal health, with potential effects also on the future development of adult diseases in the offspring. Nevertheless, few data are available on the nutritional management of pregnant women with CKD and the main clinical indications are based on small case series or are extrapolated from the general recommendations for non-pregnant CKD patients. In this review, we discuss the main issues regarding the nutritional management of pregnant women with renal diseases, including CKD patients on conservative treatment, patients on dialysis and kidney transplant patients, focusing on their relevance on fetal outcomes and considering the peculiarities of this population and the approaches that could be implemented into clinical practice.
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Buck, Stuart, Joe Rolfe, Craig Lemin, and Bernie English. "Adoption, profitability and future of leucaena feeding systems in Australia." Tropical Grasslands-Forrajes Tropicales 7, no. 4 (September 3, 2019): 303–14. http://dx.doi.org/10.17138/tgft(7)303-314.
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Keynote paper presented at the International Leucaena Conference, 1‒3 November 2018, Brisbane, Queensland, Australia.Leucaena (Leucaena leucocephala ssp. glabrata) is a highly palatable and productive forage used mainly by beef producers on extensive properties in northern Australia. When sown into native or sown grass pastures, leucaena provides significant production, economic, environmental and social benefits. Adoption of leucaena was slow initially due to a range of technical, agronomic and landscape factors. These have now been largely overcome through extensive research, development, producer experience and other advances, resulting in around 130,000 ha of cultivated leucaena being utilized across northern Australia.A range of aspects will need to be addressed if the adoption of leucaena is to be accelerated into the future. These include environmental concerns, especially potential weediness, and a range of technological needs, including soil nutritional requirements, grazing and toxicity management, opportunities for companion fodder systems and conservation options. Advances in technology and the ongoing need for a high-quality, profitable and sustainable perennial forage will ensure the continued adoption of leucaena across northern Australia for the foreseeable future.
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Mahle, Amanda Caroline, Bernard David Morris, Zane Frazer, and Christopher Novak. "Severe vitamin deficiencies in pregnancy complicated by progressive familial intrahepatic cholestasis." BMJ Case Reports 14, no. 3 (March 2021): e240248. http://dx.doi.org/10.1136/bcr-2020-240248.
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Progressive familial intrahepatic cholestasis (PFIC) is a rare disease of impaired bile acid excretion which can lead to nutritional deficiencies. Vitamin deficiencies during pregnancy can result in adverse maternal and fetal outcomes. A 20-year-old primiparous woman at 30 4/7 weeks with PFIC type 2 presented with worsening cholestasis, coagulopathy and fat-soluble vitamin deficiency. She developed visual deficits and was found to have severe vitamin A deficiency. Her coagulopathy and visual deficits improved following vitamin K and A supplementation, respectively. She delivered at 32 2/7 weeks following preterm labour. This case highlights several unique aspects in the care of pregnant women with liver disease. These patients are at risk for fat-soluble vitamin deficiencies which can result in significant coagulopathy and rarely, visual deficits due to vitamin A deficiency. Prompt treatment is necessary to prevent permanent sequelae.
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Alekseeva, Y. A., T. A. Khoroshailo, A. A. Brichagina, and O. V. Svitenko. "Ecological and raw material aspects of the production of fermented milk drinks." IOP Conference Series: Earth and Environmental Science 981, no. 2 (February 1, 2022): 022082. http://dx.doi.org/10.1088/1755-1315/981/2/022082.
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Abstract Many works have been devoted to the problem of obtaining healthy drinks. The nutritional value of fermented milk products depends on the composition and properties of the feedstock, the quantitative and qualitative composition of the components included in the recipe, conditions and operating parameters at all stages of the technological process, as well as on the level of technological equipment of the enterprise. In Russia, over the past year, a total of 2.159.182 tons of fermented milk products were produced, of which 794.294 tons were yogurt, 194.177 tons were fermented baked milk and varenets, 16.004 tons were yogurt, and 907.453 tons were kefir. Kefir is a fermented milk product obtained from cow’s milk by fermentation with the use of special «fungi», which is a mixture of various microorganisms. It is eaten both separately and as part of a large number of culinary and confectionery dishes. It is popular in Russia, CIS, Europe, America and Australia.
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Zakharova, Irina N., Narine G. Sugian, Angelina A. Kosareva, Natalia V. German, Iana V. Orobinskaia, and Viktoriya V. Pupykina. "Motherhood and infant feeding: Historical aspects and current practice: A review." Pediatrics. Consilium Medicum, no. 4 (January 18, 2023): 278–85. http://dx.doi.org/10.26442/26586630.2022.4.201762.
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In recent years there has been a deterioration in demographic indicators: a decrease in the birth rate, an increase in adult mortality, etc., due to numerous causes. In this context, the article addresses demographic issues related to subcultures and ideologies, such as childfree. The main characteristics of people classified as rejecters, aficionados, refusers, and postponers are discussed. We present the first results of a study conducted at the Khimki regional hospital. The study included 25 pregnant women. The survey results showed that most were planning a pregnancy before 30. A survey of expectant mothers indicated a positive attitude towards breastfeeding. The article discusses the issues of breastfeeding as an essential stage in forming a child's immunity and the factors of breastfeeding success. Women's nutrition during pregnancy and breastfeeding should be diverse and rich in vitamins and micronutrients. Special maternal drinks, such as Amalthea, based on New Zealand goat milk, can benefit breastfeeding. In the absence of breast milk, the selection of formula for the baby is one of the most challenging issues. It is important that the infant formula meet the child's nutritional needs to the maximum extent possible, including the functional milk components. For instance, the Nanny formula is based on New Zealand goat milk, using a single heat treatment process without separating milk into fractions, which preserves the native functional components of goat milk (oligosaccharides, nucleotides, milk fat).
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McCrabb, G. J., A. R. Egan, and B. J. Hosking. "Maternal undernutrition during mid-pregnancy in sheep: variable effects on placental growth." Journal of Agricultural Science 118, no. 1 (February 1992): 127–32. http://dx.doi.org/10.1017/s002185960006809x.
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SUMMARYThe effect of maternal undernutrition between the 30th and 96th day of pregnancy on placental growth in single-bearing ewes was determined separately in two experiments in consecutive years (1986 and 1987) at Mount Derrimut Field Station, Deer Park, Australia. In the first experiment, placental growth measured on the 96th day of pregnancy was reduced (473 v. 596 g) by maternal undernutrition, while in the second, placental growth was increased (600 v. 496 g). Foetal weight and its linear dimensions on the 96th day of pregnancy were not significantly affected by maternal u dernutrition in either experiment. The only significant difference in the animals and experimental conditions between the two studies was the liveweight of the ewes at mating, which was c. 10 kg higher in the second experiment compared with the first (P < 0·01). Body condition score and the change in condition score during the respective nutritional treatments were not significantly different between the two experiments. The results suggest that maternal liveweight, possibly body reserves not quantifiable by condition score, protects and even enhances placental growth during a period of maternal undernutrition.
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Warner, John O., and Jill Amanda Warner. "The Foetal Origins of Allergy and Potential Nutritional Interventions to Prevent Disease." Nutrients 14, no. 8 (April 12, 2022): 1590. http://dx.doi.org/10.3390/nu14081590.
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The first nine months from conception to birth involves greater changes than at any other time in life, affecting organogenesis, endocrine, metabolic and immune programming. It has led to the concept that the “first 1000 days” from conception to the second birthday are critical in establishing long term health or susceptibility to disease. Immune ontogeny is predominantly complete within that time and is influenced by the maternal genome, health, diet and environment pre-conception and during pregnancy and lactation. Components of the immunological protection of the pregnancy is the generation of Th-2 and T-regulatory cytokines with the consequence that neonatal adaptive responses are also biased towards Th-2 (allergy promoting) and T-regulatory (tolerance promoting) responses. Normally after birth Th-1 activity increases while Th-2 down-regulates and the evolving normal human microbiome likely plays a key role. This in turn will have been affected by maternal health, diet, exposure to antibiotics, mode of delivery, and breast or cow milk formula feeding. Complex gene/environment interactions affect outcomes. Many individual nutrients affect immune mechanisms and variations in levels have been associated with susceptibility to allergic disease. However, intervention trials employing single nutrient supplementation to prevent allergic disease have not achieved the expected outcomes suggested by observational studies. Investigation of overall dietary practices including fresh fruit and vegetables, fish, olive oil, lower meat intake and home cooked foods as seen in the Mediterranean and other healthy diets have been associated with reduced prevalence of allergic disease. This suggests that the “soup” of overall nutrition is more important than individual nutrients and requires further investigation both during pregnancy and after the infant has been weaned. Amongst all the potential factors affecting allergy outcomes, modification of maternal and infant nutrition and the microbiome are easier to employ than changing other aspects of the environment but require large controlled trials before recommending changes to current practice.
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Kelly, RW. "Lamb mortality and growth to weaning in commercial Merino flocks in Western Australia." Australian Journal of Agricultural Research 43, no. 6 (1992): 1399. http://dx.doi.org/10.1071/ar9921399.
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Eighteen farm flocks of four-tooth Merino ewes (average of 371 ewes at lamb marking, range 278 to 511) were studied in 1987/88 ( n =8 ) and 1988/89 (n=10) over the period from 2 to 4 weeks pre-joining until 12 weeks post-lambing. All farms were located in the south-west of Western Australia, and the flocks started lambing between mid-April and mid-July. The average liveweights of ewes pre-joining ranged over 40.2 to 61.8 kg, and average condition scores ranged from 2.2 to 4.2. Mean liveweight changes of the ewes ranged over losses of up to 8.5 kg to gains of up to 10.4 kg between consecutive recordings at 2 to 3 month intervals up to 12 weeks post lambing, and condition score changes ranged over minus 1.2 to plus 1.2. The greatest losses in liveweight and condition score in many flocks corresponded with the period from mid-pregnancy to marking, the time of greatest nutrient demand of the ewe. There was considerable variation between flocks in the percentage of dry ewes (2.9 to 17.7%), lambs born per ewe present at marking (83.0 to 147.3%), lambs alive per ewe present at marking (66.3 to 123.2%), and lamb deaths as a percentage of total lambs born (10.9 to 29.8%). For single and twin-born lambs, the percentage of lamb deaths between flocks ranged from 6.0 to 19.9% (mean = 11.0%) and 19.1 to 63.2% (mean = 33.1%) respectively. Of the ewes giving birth to twins, an average of 9.6% lost both lambs. The mean birthweights were 4.4 kg (range 3.6 to 5.1 kg) for singles and 4.0 kg (range 3.3 to 4.5 kg) for twins, and were highly correlated (r = 0 - 74, n = 13 flocks, P<0.01). Lamb growth to marking averaged 232 g head-1 day-1 and 205 g head-1 day-1, and from marking to weaning 198 g head-1 day-1 and 193 g head-1 day-1 for single and twin-born lambs respectively. The mortality rates of both single and twin-born lambs were highly correlated with mean liveweight of the ewes at mid-pregnancy (r = -0.64, P<0.01; r = -0.75, P<0.001; respectively). A kilogram increase in mean liveweight at mid-pregnancy was associated with declines in the mortality rates of single-born lambs of 0.7% units (s.e. = 0.23), and of twin-born lambs of 2.2% units (s.e. = 0.57). Mortality rates of the singles were highly correlated with that of twins (r = 0.86, P<0.001), with a 1% unit change in death rate of singles being associated with a 2.5% (s.e. = 0.41) unit change for twins. Mortality rates of twins were associated with mean cotyledon diameter measured in mid-pregnancy (r = -0.48, n = 13, P<0. l0), and mean umbilical resistance to blood flow (r = 0.78, n = 9, P<0.02). Growth from birth to weaning of single-born lambs was associated with the mean liveweight of the flock in mid-pregnancy (r = 0.72, P<0 .001). Clean fleece weight and mean fibre diameter of the fleeces from single.bearing and rearing ewes were correlated with mean ewe liveweight in mid-pregnancy (r = 0.56, P<0.05; r = 0.70, P<0.01; respectively). Staple strength was correlated with mean ewe liveweight at marking for both single and twin producing ewes (r = 0.72, n = 18, P<0.01; r = 0.74, n = 9, P<0.05; respectively). It was concluded that liveweight of the ewe in mid-pregnancy, which represents the sum of starting liveweight and liveweight change, is the most important single and practical criterion that can be used by a farmer to set the goals for nutritional management of the flock over pregnancy to improve lamb survival.
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Schmoelzl, Sabine, and Fran Cowley. "The case for pre-parturient selenium and iodine supplementation of ewes for improving lamb survival." Animal Production Science 56, no. 8 (2016): 1263. http://dx.doi.org/10.1071/an15362.
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Lamb survival is an issue of high relevance to the Australian sheep industry, as lamb-survival rates have direct bearing on overall reproductive performance of the sheep, and also constitute a main concern from an animal welfare perspective (Mellor and Stafford 2004). Both genetic and management factors play an important role in this complex issue (Hinch and Brien 2014). Ewe nutrition is of particular relevance as the intrauterine growth conditions prepare the lamb for the crucial transition to life outside the uterus. Effects of body condition of the ewe during various stages of the pregnancy have been investigated in detail, yet much less is known about the critical role of micronutrient provision to the ewe. Although several risk factors for selenium (Se) and iodine (I) subclinical deficiencies exist for sheep on pasture in Australia, determining micronutrient status in sheep or pasture is not straightforward. Several studies have separately found effects of Se and I supplementation on lamb survival. Studies investigating the interaction of Se and I supplementation have been few but results have demonstrated an interaction between Se and I. With increased twinning rates as a result of increased selection of numbers of lambs weaned, nutritional demands during pregnancy across flocks are increasing, and effects of micronutrients on lamb health and survival have greater impact. New opportunities in nutritional research are encouraging new studies into the effects of Se and I supplementation on lamb survival.
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Masters, David G., and Andrew N. Thompson. "Grazing crops: implications for reproducing sheep." Animal Production Science 56, no. 4 (2016): 655. http://dx.doi.org/10.1071/an14517.
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Integration of crops and livestock has been revitalised in Australia, initially as an opportunity to increase cropping within the high-rainfall grazing zones, and more recently, to improve enterprise diversification and profitability across the low-, medium- and high-rainfall, and mixed-farming zones. Young crops are highly digestible (>80% dry matter digestibility, DMD) with a high energy density (>12 MJ/kg DM) and, in much of southern Australia, fill a winter feed gap. The quality and time of feed availability also coincide with the high nutrient requirements of ewes in late pregnancy and lactation. In Western Australia and South Australia, young crops are available for lactating ewes and young growing lambs (autumn lambing). For the smaller proportion of growers who lamb later in winter, young crops are available for the last 1–2 months of pregnancy. In the later-lambing states of New South Wales and Victoria, crops may be grazed by ewes at any stage of pregnancy and lactation and/or by young lambs. In Tasmania, crops are more likely to be available during early–mid-gestation. Limited studies on feed budgeting with grazing crops have indicated that ewes can maintain or even increase liveweight, with a much lower level of feed on offer than would be required with traditional pastures (<500 kg DM/ha). This has the potential to increase whole-farm stocking rates and/or reduce fetal mortality, increase lamb birthweight and survival and improve lifetime production. Maintaining or increasing ewe liveweight during pregnancy and lactation may also result in heavier ewes the following year and higher ovulation rates. Pregnancy and lactation are also periods of increased susceptibility to metabolic disturbances. The composition of young crops increases this susceptibility. Pregnancy toxaemia, hypocalcaemia and hypomagnesaemia can influence ewe health and fetal survival. Chronic acidosis and excessive ammonia absorption from rapid introduction of pregnant ewes onto young crops may risk appetite loss and increase susceptibility to pregnancy toxaemia. Low magnesium and sodium combined with high potassium increases the risk of grass tetany. Most young crops (except canola) also have a tetany index >2.2, indicating a high risk of grass tetany. The elevated potassium also contributes to a high dietary cation–anion difference of approximately +49 mEq/100 g DM and this may cause metabolic alkalosis and hypocalcaemia. Pregnancy toxaemia, hypocalcaemia and grass tetany are all potential causes of increased ewe mortality. Pregnancy and/or lactation outcomes will also be influenced by a deficiency of trace elements. Grazing young crops in areas with a history of selenium, copper, iodine and cobalt deficiency will increase susceptibility to deficiency by increasing growth and feed intake. In conclusion, the grazing of young growing crops presents new opportunities for increased production and stocking rates in the mixed-farming zones. The value of this feed source is well recognised by some producers. While growing crops have a highly productive potential, they also come with an increased risk of a range metabolic disturbances and nutritional imbalances. These risks can be minimised by regular monitoring of livestock and crop biomass and the provision of mineral supplements.
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Ristori, Maria Vittoria, Andrea Quagliariello, Sofia Reddel, Gianluca Ianiro, Stefano Vicari, Antonio Gasbarrini, and Lorenza Putignani. "Autism, Gastrointestinal Symptoms and Modulation of Gut Microbiota by Nutritional Interventions." Nutrients 11, no. 11 (November 18, 2019): 2812. http://dx.doi.org/10.3390/nu11112812.
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Autism spectrum disorder (ASD) is a complex behavioral syndrome that is characterized by speech and language disorders, intellectual impairment, learning and motor dysfunctions. Several genetic and environmental factors are suspected to affect the ASD phenotype including air pollution, exposure to pesticides, maternal infections, inflammatory conditions, dietary factors or consumption of antibiotics during pregnancy. Many children with ASD shows abnormalities in gastrointestinal (GI) physiology, including increased intestinal permeability, overall microbiota alterations, and gut infection. Moreover, they are “picky eaters” and the existence of specific sensory patterns in ASD patients could represent one of the main aspects in hampering feeding. GI disorders are associated with an altered composition of the gut microbiota. Gut microbiome is able to communicate with brain activities through microbiota-derived signaling molecules, immune mediators, gut hormones as well as vagal and spinal afferent neurons. Since the diet induces changes in the intestinal microbiota and in the production of molecules, such as the SCFA, we wanted to investigate the role that nutritional intervention can have on GI microbiota composition and thus on its influence on behavior, GI symptoms and microbiota composition and report which are the beneficial effect on ASD conditions.
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Levitsky, I. V., and N. M. Kinash. "MODERN ASPECTS OF THE ETIOPATHOGENESIS OF ISTMIC-CERVICAL INSUFFICIENCY." Art of Medicine 22, no. 2 (July 20, 2022): 136–41. http://dx.doi.org/10.21802/artm.2022.2.22.136.
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Isthmic-cervical insufficiency (ICI), which results in the failure of the circular muscles of the internal os, isthmus and cervix of the uterus is important in the pathogenesis of preterm birth. The existing types are anatomical, functional and congenital ICI. ICI is a pathological condition of the cervix and the isthmus, in which they are unable to withstand the intrauterine pressure and keep a fertilized egg in the uterine cavity until birth. ICI is a serious complication of pregnancy. Genetic, hormonal, inflammatory-infectious, immunological, traumatic factors play a role in the occurrence of ICI. The aim of the study is to study the peculiarities of reproductive health and gestational process of pregnant women with ICI, according to the literature. For the study, we analyzed domestic and foreign publications on this topic in professional journals, as well as data from Internet resources. Results of the research show that ICI plays a special role among many causes that lead to preterm termination of pregnancy and premature birth in the II-III trimesters. The properties of the cervix depend on the ratio of connective and muscle tissue. Today, most authors distinguish between congenital, acquired, organic and functional isthmic-cervical insufficiency.Organic (post-traumatic, secondary) ICI occurs due to mechanical damage to the cervix. Functional ICI is the result of a violation of the relationship between the muscular and connective tissues of the cervix, as well as the result of changes in the response of its structural elements to neurohumoral stimuli. Functional ICI most often occurs as a consequence of a violation of the hormonal background of women (ovarian hypofunction, hyperandrogenism). Congenital ICI occurs in malformations of the uterus, genital infantilism. Histological examination of cervical tissue in women with ICI reveals an increase in muscle tissue up to 50%, which leads to early softening of the cervix of the uterus and development of its functional insufficiency. According to Kaufman KP (2021), the role of connective tissue in the development of ICI is confirmed by the fact, that this pathological condition of the cervix is found in women with Marfan syndrome and Ehlers-Danlos syndrome. The role of undifferentiated connective tissue dysplasia (UCTD) as a risk factor for complicated pregnancy, including ICI.Research of Huang J and co-authors (2021) found the presence of nutritional imbalance in patients with UCTD, which was manifested by changes in serum concentrations of magnesium, calcium, zinc, iron, copper, selenium, inorganic phosphorus. The relationship between changes in the microcirculation system, tissue perfusion and cervical condition is currently being actively discussed and confirmed in numerous studies.Fettweis JM (2019) believes that the mechanism of abortion at different stages of gestation is not the same in pregnant women with ICI. At the same time, all pregnant women with ICI at all stages of gestation have increased cytokine levels. However, an important factor in the premature termination of pregnancy in ICI is assigned to the infectious factor. The results of the study of the pathogenetic role of local immune responses in women with habitual miscarriage are often contradictory and dictate the need for further researches.Eventually, isthmic-cervical insufficiency is a multifactorial complication of pregnancy, in which genetic, hormonal, inflammatory-infectious, immunological or traumatic factors play a role.
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Eileen Owan, Diane E Heck, and Hong Duck Kim. "Autism spectrum disorder is associated with multifold risks in the process of pregnancy: Imbalance of nutritional, environmental and social behavioral aspects." GSC Advanced Research and Reviews 13, no. 1 (October 30, 2022): 018–22. http://dx.doi.org/10.30574/gscarr.2022.13.1.0255.
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Autism spectrum disorder (ASD) is characterized by qualitative impairments in social interaction, communication, and stereotyped behavior patterns. The cost burden for health coverage for ASD is focused on educational applied behavioral analysis and psychotropic drugs to decrease maladaptive behaviors and support learning and development. Determinants of either risk factors or prevention related to ASD covering environmental, social-behavioral, and genetic are still unknown. This review focuses on the multifold risks of Autistic disorder (ASD), including environmental, genetic, and food supplemental concerns and health policies and regulations.
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Waard, F. de, and J. H. H. Thijssen. "Hormonal aspects in the causation of human breast cancer: Epidemiological hypotheses reviewed, with special reference to nutritional status and first pregnancy." Journal of Steroid Biochemistry and Molecular Biology 97, no. 5 (December 2005): 451–58. http://dx.doi.org/10.1016/j.jsbmb.2005.08.005.
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Baraiya, A. K., K. P. Baraiya, and S. H. Lakhani. "KNOWLEDGE OF HOUSEHOLD NUTRITIONAL PRACTICES AMONG FARM WOMEN IN JAMNAGAR DISTRICT OF GUJARAT." Gujarat Journal of Extension Education 2022, no. 1 (November 25, 2022): 173–77. http://dx.doi.org/10.56572/gjoee.2022.si.0034.
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It is very truth the "knowledge/education cannot be divided, theft, not a burden, increase with sharing and usages". To perform active role in any activity, information being understood play an important role. Knowledge of any individual increases his/ her awareness, mental alertness makes him/her familiar or acquaint with facts, objects, concepts or practices. Knowledge about nutrition of a respondent was measured by some selected questions regarding different aspects of nutritional value of farm products. Selected farm women were middle age group (65.83%), all were married, and living in joint family (51%). Television (51.33%) and mobile (40%) were the most favorite source information among the nutritional requirement and supplementary food. Among the knowledge bout nutritional requirement they believed Consume more nutritive food in maximum quantity during pregnancy (rank first) (69%) followed by Papaya, mango and other yellow colour fruit & vegetable are the source of vitamin-A (63.67%); Seasonal fruits having sufficient and natural nutritional amount instead of off seasonal fruit (63.67%); Consume whole grains and sprouted pulses in daily diet (63%); Daily consumption of different millets (Bajari, sorghum, maize, oat, ragi, rice with husk) reduce the risk of diabetes, heart attack, obesity etc.(60.67%) and Amla and guava and other sour(Acidic) fruits are the rich sources of Vitamin C (60%) were chronologically decline the rank.
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Paganoni, B. L., C. M. Oldham, M. B. Ferguson, A. N. Thompson, P. E. Vercoe, and D. G. Gordon. "Ewe nutrition during pregnancy and birthweight of lambs has minimal impact on fat and eye muscle depth in Merino progeny." Animal Production Science 53, no. 6 (2013): 509. http://dx.doi.org/10.1071/an12266.
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The hypothesis tested in this experiment was that Merino lambs with lower birthweights, due to poor ewe nutrition during pregnancy, would have more fat and less muscle than Merino lambs with higher birthweights. At two sites (Victoria and Western Australia) in each of 2 years, a wide range in the liveweight profiles of ewes was generated during pregnancy and lactation by varying the amount of supplements fed and feed on offer grazed. Progeny had fat and muscle depth at the C-site measured at various ages from 8 to 28 months of age. Across the four experiments, there were differences of 0.5 kg in birthweights and 8 kg in weaning weights between extreme treatments. The effects on the depth of fat and muscle were very small with fat depth increasing by 0.1–0.2 mm (5–7%) and muscle depth increasing by 0.2–0.7 mm (1–3%) when birthweights decreased by 1 kg. The effects of birthweight on fat depth are consistent with our hypothesis whereas the effects of birthweight on muscle depth are in contrast to our hypothesis. Nevertheless, the impacts of birthweight on the depth of fat and muscle measured at the C-site of progeny from Merino ewes, is unlikely to be of any commercial significance within the range of nutritional scenarios during pregnancy and lactation that are likely to be experienced within the Australian sheep industry.
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Valentini, Romina, Maria Grazia Dalfrà, Michela Masin, Antonella Barison, Marcon Marialisa, Eva Pegoraro, and Annunziata Lapolla. "A Pilot Study on Dietary Approaches in Multiethnicity: Two Methods Compared." International Journal of Endocrinology 2012 (2012): 1–6. http://dx.doi.org/10.1155/2012/985136.
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Background. Medical nutritional therapy is the most important method for normalizing glucose levels in pregnancy. In this setting, there is a new problem to consider relating to migrants, their personal food preferences, and ethnic, cultural, and religious aspects of their diet. We compared maternal and fetal outcomes between two multiethnic groups of pregnant women, one adopting a food plan that included dishes typical of the foreign women's original countries (the “ethnic meal plan” group), while the other group adopted a standard meal plan.Findings. To develop the meal plan, each dish chosen by the women was broken down into its principal ingredients. The quantity of each food was given in tablespoons, teaspoons, slices, and cups, and there were photographs of the complete dish. The group treated with the ethnic meal plan achieved a better metabolic control at the end of the pregnancy and a lower weight gain (though the difference was not statistically significant). As for fetal outcome, the group on the ethnic meal plan had babies with a lower birth weight and there were no cases of macrosomia or LGA babies.Conclusions. This preliminary study indicates the positive effect of an ethnic approach to diet on the outcome of pregnancy.
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PINI, Taylor, Gulfam AHMAD, Romain BARRES, Stephen SIMPSON, and Angela CREAN. "Nutritional Geometry of Male Fertility: Moving Beyond The ‘High-Fat’ Diet." Fertility & Reproduction 04, no. 03n04 (September 2022): 179. http://dx.doi.org/10.1142/s2661318222740905.
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Background: Females are given extensive dietary recommendations both during and prior to pregnancy, but similar guidelines for males trying to conceive are conspicuously absent. There is an urgent need to fill this knowledge gap because male fertility is in decline, with rising rates of obesity likely to be a contributing factor. Yet, we understand surprisingly little about nutritional impacts on male fertility. Aim: To examine the individual and interactive effects of protein, carbohydrates, and fats on male reproductive traits, we conducted a nutritional geometry study in adolescent C57Bl6 male mice. Method: Mice were fed one of ten isocaloric diets differing only in macronutrient balance (n = 6/diet) from 5 to 20 weeks of age. Reproductive organs were fixed/frozen and processed for a range of fertility-related measures. Results: We found that different aspects of reproductive function were influenced by different macronutrients. Testis mass and expression of HSD17B3 (testosterone biosynthesis) were positively related to the proportion of protein in the diet. In contrast, dietary fat had a stronger influence on male body mass and seminal vesicle mass. Both dietary protein and fat were found to influence testicular expression of genes with antioxidant functions (GSS, GPX1, GPX4). The number of seminiferous tubules and degree of vacuolation within seminiferous tubules were influenced by complex interactive effects between macronutrients. Conclusion: This foundational study suggests that a far more nuanced approach is required to develop pre-conception dietary recommendations for males, and reveals exciting new directions for research.
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Rojas-Rodriguez, Raziel, Rachel Ziegler, Tiffany DeSouza, Sana Majid, Aylin S. Madore, Nili Amir, Veronica A. Pace, et al. "PAPPA-mediated adipose tissue remodeling mitigates insulin resistance and protects against gestational diabetes in mice and humans." Science Translational Medicine 12, no. 571 (November 25, 2020): eaay4145. http://dx.doi.org/10.1126/scitranslmed.aay4145.
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Pregnancy is a physiological state of continuous adaptation to changing maternal and fetal nutritional needs, including a reduction of maternal insulin sensitivity allowing for appropriately enhanced glucose availability to the fetus. However, excessive insulin resistance in conjunction with insufficient insulin secretion results in gestational diabetes mellitus (GDM), greatly increasing the risk for pregnancy complications and predisposing both mothers and offspring to future metabolic disease. Here, we report a signaling pathway connecting pregnancy-associated plasma protein A (PAPPA) with adipose tissue expansion in pregnancy. Adipose tissue plays a central role in the regulation of insulin sensitivity, and we show that, in both mice and humans, pregnancy caused remodeling of adipose tissue evidenced by altered adipocyte size, vascularization, and in vitro expansion capacity. PAPPA is known to be a metalloprotease secreted by human placenta that modulates insulin-like growth factor (IGF) bioavailability through prolteolysis of IGF binding proteins (IGFBPs) 2, 4, and 5. We demonstrate that recombinant PAPPA can stimulate ex vivo human adipose tissue expansion in an IGFBP-5– and IGF-1–dependent manner. Moreover, mice lacking PAPPA displayed impaired adipose tissue remodeling, pregnancy-induced insulin resistance, and hepatic steatosis, recapitulating multiple aspects of human GDM. In a cohort of 6361 pregnant women, concentrations of circulating PAPPA are inversely correlated with glycemia and odds of developing GDM. These data identify PAPPA and the IGF signaling pathway as necessary for the regulation of maternal adipose tissue physiology and systemic glucose homeostasis, with consequences for long-term metabolic risk and potential for therapeutic use.
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Fealy, Shanna, Jenna Hollis, Julia Martin, Lucy Leigh, Christopher Oldmeadow, Clare E. Collins, Roger Smith, Shelley Wilkinson, and Alexis Hure. "Modeling the Predictive Value of Evidence-Based Referral Criteria to Support Healthy Gestational Weight Gain among an Australian Pregnancy Cohort." Nutrients 14, no. 2 (January 17, 2022): 381. http://dx.doi.org/10.3390/nu14020381.
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Globally, there has been a renewed focus on addressing gestational weight gain (GWG). In Australia, the Department of Health pregnancy care guidelines recommend women be offered routine weighing and receive brief nutritional and physical activity support during antenatal care visits. Women gaining weight outside the Institute of Medicine (IOM)’s weight gain reference values are further recommended to be referred to a dietitian. However, professional and organizational barriers, including an absence of weight gain referral pathways and limited workforce resources, exist with the translation and scaling of these recommendations into practice. This study aimed to explore patterns of GWG among a cohort of Australian pregnant women and to determine if pregnancy weight gains of above or below 2 kg or 5 kg in the second and third trimester can be used to predict total GWG outside recommendations. Sensitivity, specificity, negative, and positive likelihood ratios were calculated. The most predictive time point was 24 weeks’ gestation using the minimum weight change parameter of +/−2 kg, demonstrating reasonable sensitivity (0.81, 95% CI 0.61–0.83) and specificity (0.72, 95% CI 0.61–0.83), resulting in 55% (n = 72/131) of the cohort qualifying for dietetic referral. Given the current health service constraints, a review of dietetic services within maternity care is warranted.
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Dahlen, Carl R., Pawel P. Borowicz, Alison K. Ward, Joel S. Caton, Marta Czernik, Luca Palazzese, Pasqualino Loi, and Lawrence P. Reynolds. "Programming of Embryonic Development." International Journal of Molecular Sciences 22, no. 21 (October 28, 2021): 11668. http://dx.doi.org/10.3390/ijms222111668.
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Assisted reproductive techniques (ART) and parental nutritional status have profound effects on embryonic/fetal and placental development, which are probably mediated via “programming” of gene expression, as reflected by changes in their epigenetic landscape. Such epigenetic changes may underlie programming of growth, development, and function of fetal organs later in pregnancy and the offspring postnatally, and potentially lead to long-term changes in organ structure and function in the offspring as adults. This latter concept has been termed developmental origins of health and disease (DOHaD), or simply developmental programming, which has emerged as a major health issue in animals and humans because it is associated with an increased risk of non-communicable diseases in the offspring, including metabolic, behavioral, and reproductive dysfunction. In this review, we will briefly introduce the concept of developmental programming and its relationship to epigenetics. We will then discuss evidence that ART and periconceptual maternal and paternal nutrition may lead to epigenetic alterations very early in pregnancy, and how each pregnancy experiences developmental programming based on signals received by and from the dam. Lastly, we will discuss current research on strategies designed to overcome or minimize the negative consequences or, conversely, to maximize the positive aspects of developmental programming.
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Muggli, Evelyne, Jane Halliday, Elizabeth J. Elliott, Anthony Penington, Deanne Thompson, Alicia Jane Spittle, Della Forster, Sharon Lewis, Stephen Hearps, and Peter J. Anderson. "Cohort profile: early school years follow-up of the Asking Questions about Alcohol in Pregnancy Longitudinal Study in Melbourne, Australia (AQUA at 6)." BMJ Open 12, no. 1 (January 2022): e054706. http://dx.doi.org/10.1136/bmjopen-2021-054706.
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PurposeThe Asking Questions about Alcohol in Pregnancy (AQUA) study, established in 2011, is a prebirth cohort of 1570 mother and child pairs designed to assess the effects of low to moderate prenatal alcohol exposure and sporadic binge drinking on long-term child development. Women attending general antenatal clinics in public hospitals in Melbourne, Australia, were recruited in their first trimester, followed up three times during pregnancy and at 12 and 24 months postpartum. The current follow-up of the 6–8-year-old children aims to strengthen our understanding of the relationship between these levels of prenatal alcohol exposure and neuropsychological functioning, facial dysmorphology, brain structure and function.ParticipantsBetween June 2018 and April 2021, 802 of the 1342 eligible AQUA study families completed a parent-report questionnaire (60%). Restrictions associated with COVID-19 pandemic disrupted recruitment, but early school-age neuropsychological assessments were undertaken with 696 children (52%), and 482 (36%) craniofacial images were collected. A preplanned, exposure-representative subset of 146 children completed a brain MRI. An existing biobank was extended through collection of 427 (32%) child buccal swabs.Findings to dateOver half (59%) of mothers consumed some alcohol during pregnancy, with one in five reporting at least one binge-drinking episode prior to pregnancy recognition. Children’s craniofacial shape was examined at 12 months of age, and low to moderate prenatal alcohol exposure was associated with subtle midface changes. At 2 years of age, formal developmental assessments showed no evidence that cognitive, language or motor outcome was associated with any of exposure level.Future plansWe will investigate the relationship between prenatal alcohol exposure and specific aspects of neurodevelopment at 6–8 years, including craniofacial shape, brain structure and function. The contribution of genetics and epigenetics to individual variation in outcomes will be examined in conjunction with national and international collaborations.
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Di Marco, Nelfio, Jonathan Kaufman, and Christine Rodda. "Shedding Light on Vitamin D Status and Its Complexities during Pregnancy, Infancy and Childhood: An Australian Perspective." International Journal of Environmental Research and Public Health 16, no. 4 (February 13, 2019): 538. http://dx.doi.org/10.3390/ijerph16040538.
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Ensuring that the entire Australian population is Vitamin D sufficient is challenging, given the wide range of latitudes spanned by the country, its multicultural population and highly urbanised lifestyle of the majority of its population. Specific issues related to the unique aspects of vitamin D metabolism during pregnancy and infancy further complicate how best to develop a universally safe and effective public health policy to ensure vitamin D adequacy for all. Furthermore, as Australia is considered a “sunny country”, it does not yet have a national vitamin D food supplementation policy. Rickets remains very uncommon in Australian infants and children, however it has been recognised for decades that infants of newly arrived immigrants remain particularly at risk. Yet vitamin D deficiency rickets is entirely preventable, with the caveat that when rickets occurs in the absence of preexisting risk factors and/or is poorly responsive to adequate treatment, consideration needs to be given to genetic forms of rickets.
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Emmerich, Nathan, and Christine Phillips. "Should professional interpreters be able to conscientiously object in healthcare settings?" Journal of Medical Ethics 46, no. 10 (December 3, 2019): 700–704. http://dx.doi.org/10.1136/medethics-2019-105767.
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In a globalised world, healthcare professionals will inevitably find themselves caring for patients whose first language differs from their own. Drawing on experiences in Australia, this paper examines a specific problem that can arise in medical consultations using professional interpreters: whether the moral objections of interpreters should be accommodated as conscientious objections if and when their services are required in contexts where healthcare professionals have such entitlements, most notably in relation to consultations concerning termination of pregnancy and voluntary assisted dying. We argue that existing statements of professional ethics suggest that interpreters should not be accorded such rights. The social organisation of healthcare and interpreting services in Australia may mean those who have serious objections to particular medical practices could provide their services in restricted healthcare contexts. Nevertheless, as a general rule, interpreters who have such objections should avoid working within healthcare.
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Banerjee, Swapan. "Role of the Proper Nutrition for Indian Women with Recurrent Pregnancy Loss (RPL)." Dec 2022-Jan 2023, no. 31 (December 16, 2022): 1–9. http://dx.doi.org/10.55529/jpdmhd.31.1.9.
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Two or more miscarriages or biochemical pregnancy losses are treated as recurrent pregnancy loss (RPL). Conditions like immune deficiency, thrombophilia, endocrine dysfunction, and obesity have all been linked to an increased likelihood of miscarriage. There is currently no documented treatment for repeated miscarriages; hence, diet and drug aspects must be implemented nationally or internationally. Databases like Google Scholar, the Directory of Open Access Journals (DOAJ), Semantic Scholar, etc., were used to find publications relevant to this study's objectives. From the Indian perspective, a pregnant woman's daily calorie intake should increase by 350, with an additional 9.5 g of protein in the second and 22.0 g in the third trimester. Prenatal folic acid supplementation has been linked to managing proper birth weight and reduced rates of congenital disabilities. During pregnancy, a woman's ideal weight gain is around 10 kilograms, which is the case for women who eat healthily. Limiting salt intake is necessary to prevent hypertension or preeclampsia during pregnancy. Coffee, tea, and other caffeinated drinks should be used in moderation. Vegetables like papaya, cabbage, pumpkin, milk derivatives, sugar cane, and fruits like bananas, mangoes, pineapple, avocados, etc., are the most taboo foods in developing countries like India and Africa. The widespread avoidance of these foods during pregnancy can be attributed to myths that they contribute to foetal obesity, evil eye, abortion, and other delivery difficulties. In rural India, pregnant women are primarily not adequately informed about the significance of eating a healthy, well-rounded diet. To ensure maternal dietary diversity, even modest; well-targeted awareness-raising programs should go a long way. Hence expected mothers should get compulsory nutritional guidance on what to eat and how much from experts like dietitians, physicians, or other experienced mothers through personal meetings or social media platforms to minimize recurrent pregnancy loss.
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Armitage, Andrew E., and Diego Moretti. "The Importance of Iron Status for Young Children in Low- and Middle-Income Countries: A Narrative Review." Pharmaceuticals 12, no. 2 (April 16, 2019): 59. http://dx.doi.org/10.3390/ph12020059.
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Early childhood is characterised by high physiological iron demand to support processes including blood volume expansion, brain development and tissue growth. Iron is also required for other essential functions including the generation of effective immune responses. Adequate iron status is therefore a prerequisite for optimal child development, yet nutritional iron deficiency and inflammation-related iron restriction are widespread amongst young children in low- and middle-income countries (LMICs), meaning iron demands are frequently not met. Consequently, therapeutic iron interventions are commonly recommended. However, iron also influences infection pathogenesis: iron deficiency reduces the risk of malaria, while therapeutic iron may increase susceptibility to malaria, respiratory and gastrointestinal infections, besides reshaping the intestinal microbiome. This means caution should be employed in administering iron interventions to young children in LMIC settings with high infection burdens. In this narrative review, we first examine demand and supply of iron during early childhood, in relation to the molecular understanding of systemic iron control. We then evaluate the importance of iron for distinct aspects of physiology and development, particularly focusing on young LMIC children. We finally discuss the implications and potential for interventions aimed at improving iron status whilst minimising infection-related risks in such settings. Optimal iron intervention strategies will likely need to be individually or setting-specifically adapted according to iron deficiency, inflammation status and infection risk, while maximising iron bioavailability and considering the trade-offs between benefits and risks for different aspects of physiology. The effectiveness of alternative approaches not centred around nutritional iron interventions for children should also be thoroughly evaluated: these include direct targeting of common causes of infection/inflammation, and maternal iron administration during pregnancy.
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Muñóz Muñóz, Aránzazu, Sagrario Gómez-Cantarino, María de las Mercedes De Dios Aguado, Minerva Velasco Abellán, Beatríz González López, Brigida Molina Gallego, Juan Luis González Pascual, and Natalia María Arias Palencia. "Nutritional habits and levels of physical activity during pregnancy, birth and the postpartum period of women in Toledo (Spain): study protocol for a two-year prospective cohort study (the PrePaN study)." BMJ Open 9, no. 7 (July 2019): e029487. http://dx.doi.org/10.1136/bmjopen-2019-029487.
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IntroductionPregnant women who eat a balanced diet usually practice physical activity (PA) regularly; there are many studies on PA during pregnancy and the results for the mother and baby. However, the guideline for PA during pregnancy is very general and is not quantified. The primary objective of this study is to examine the nutritional habits and levels of PA of women during pregnancy and the postpartum period. Second, it will determine the effects of these aspects on the mother and newborn baby. Its third objective is to identify the factors which influence the practice of PA during this phase.Methods and analysisSe trata de un estudio prospectivo de cohortes que dura 2 años, f rom de septiembre de 2018 para setiembre del 2020 La muestra será reclutado en tres Atención Primaria centros en el área de salud de Toledo (España). Las participantes serán mujeres embarazadas de 18 a 40 años. Ancianos que deben asistir a todos los controles durante el embarazo y el período posparto. La PA se cuantificará utilizando la acelerometría, mientras que los hábitos nutricionales y el ejercicio físico se evaluarán mediante cuestionarios validados. Se registrarán los síntomas del embarazo y el período posparto, junto con los parámetros bioquímicos y los datos antropométricos. Los resultados primarios se determinarán en las mujeres embarazadas: aumento de peso, incidencia de diabetes mellitus gestacional, preeclampsia e hipertensión inducida por el embarazo. Los resultados secundarios incluyen la duración del embarazo y el peso al nacer, la puntuación de Apgar (1 min / 5 min), el tipo de reanimación (I / II / III / IV) y el pH de la sangre del cordón umbilical en los recién nacidos.DiscussionAlthough the beneficial effects of PA during pregnancy are known, there is a need to perform studies that quantify the amount of PA undertaken by women during pregnancy and the postpartum period. The objective of such studies is to establish science-based individualised guidelines for PA for women during this stage of their lives.
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Dixon, Rob, Stephen Anderson, Lisa Kidd, and Mary Fletcher. "Phosphorus Nutrition in Ruminants Grazing Tropical Rangelands." Proceedings 36, no. 1 (April 8, 2020): 200. http://dx.doi.org/10.3390/proceedings2019036200.
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Nutritional deficiency of phosphorus (P) is a major constraint to productivity of cattle grazing many tropical rangelands with low P soils, particularly in northern Australia, South America and Africa. Cattle growth and reproductive rates may be severely reduced. Such P deficiency is usually addressed by providing supplements containing calcium phosphates. In the seasonally dry tropics such supplements are most effective when fed during the summer rainy season when the pasture quality as energy and protein are highest. Young cattle often continue to grow slowly when P deficient, but with reduced bone mineralization. Cows with normally high bone mineral reserves (from previously P-adequate diets) can mobilize bone P during late pregnancy and lactation when diet P is insufficient. This mobilization may contribute up to ca. one-third of the P requirements and allow P-deficient cows to maintain milk production and calf growth, but is associated with reduced pasture intake and severe loss of cow liveweight. Cows can replenish bone minerals when P intake exceeds immediate requirements for growth and milk. Since on large commercial farms in rangelands it is often difficult to effectively implement P supplementation of cattle during the rainy season the mobilization and replenishment of body mineral reserves are important for managing P nutrition through the annual cycle. Biochemical markers in blood are valuable for diagnosis of P deficiency in grazing cattle. In conclusion, understanding of the nutritional physiology of cattle provides opportunities to improve management of P nutrition of cattle grazing P deficient rangelands and alleviating production losses.
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Evenosky, Sarah, Eleanor Lewis, and Katherine I. DiSantis. "A Mixed Methods Case Study of Food Shopping in a Community with High Infant Mortality." Nutrients 13, no. 11 (October 28, 2021): 3845. http://dx.doi.org/10.3390/nu13113845.
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In the U.S., preterm birth disproportionately impacts certain racial/ethnic groups, with Black women experiencing preterm birth at a rate 50% higher than other groups. Among the numerous factors that likely contribute to these increased rates are neighborhood characteristics, such as food environment. In this mixed-methods case study, we evaluated how pregnant women living in a predominately minority, lower income community with high preterm birth rates navigate and perceive their food environment. Qualitative interviews were performed to assess perceptions of food environment (n = 7) along with geographic and observational assessments of their food environment. Participants traveled an average of 2.10 miles (SD = 1.16) and shopped at an average of 3 stores. They emphasized the importance of pricing and convenience when considering where to shop and asserted that they sought out healthier foods they thought would enhance their pregnancy health. Observational assessments of stores’ nutrition environment showed that stores with lower nutritional scores were in neighborhoods with greater poverty and a higher percent Black population. Future policies and programmatic efforts should focus on improving nutrition during pregnancy for women living in communities with high rates of poor birth outcomes. Availability, affordability, and accessibility are key aspects of the food environment to consider when attempting to achieve birth equity.
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Koch, Richard, William Hanley, Harvey Levy, Kim Matalon, Reuben Matalon, Bobbye Rouse, Frederick Trefz, et al. "The Maternal Phenylketonuria International Study: 1984–2002." Pediatrics 112, Supplement_4 (December 1, 2003): 1523–29. http://dx.doi.org/10.1542/peds.112.s4.1523.
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Objective. The purpose of this report is to review the obstetric medical, psychological, and nutritional aspects and outcome of the women and offspring enrolled in the Maternal Phenylketonuria Study, which was established to assess the efficacy of a phenylalanine (Phe)-restricted diet in preventing the morbidity associated with this disorder. Methods. A total of 382 women with hyperphenylalaninemia (HPA) were enrolled in the study and completed 572 pregnancies. Outcome measures were analyzed with χ2, Fisher exact text, analysis of variance, t test, Wilcoxon nonparametric test, and multiple logistic regression. Outcome measures were stratified according to maternal HPA classification and the time when dietary control was achieved. Results. Optimal birth outcomes occurred when maternal blood Phe levels between 120 and 360 μmol/L were achieved by 8 to 10 weeks of gestation and maintained throughout pregnancy (trimester averages of 600 μmol/L). Mothers with mild HPA achieved similar birth outcomes as mothers who were in control preconceptually and those in control by 8 to 10 weeks of pregnancy. Conclusions. Before conception, counseling and early entrance into a prenatal care program is essential in achieving optimal fetal outcome in women with HPA. The achievement of pre- and periconceptional dietary control with a Phe-restricted diet significantly decreased morbidity in the offspring of women with HPA.
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Broers, Barbara, Urszula Sioma-Markowska, Barbara Królak-Olejnik, Karolina Fila-Witecka, Anna Halarewicz-Ciasullo, and Andrzej Brenk. "The evolution of natural alimentation." Medical Science Pulse 12, no. 3 (September 30, 2018): 42–46. http://dx.doi.org/10.5604/01.3001.0012.5470.
Full textAbstract:
Advances in medicine and the evolution of health-related behaviors through time and across cultures have contributed to changes in attitudes toward natural alimentation. In the past, women who breastfed their babies were educated by word of mouth and family traditions passed on by their female relatives and communities, and the act of breastfeeding itself constituted a socio-cultural process. The health-related benefits of breast milk for infant nutrition have long been known. Throughout the ages, the image of the breastfeeding woman has inspired many artists and promoted natural alimentation. Ancient beliefs and religious practices were combined with the teachings of the church as well as alchemy principles, and lactation counseling was based on popular belief rather than scientific or medical knowledge. In modern times, breastfeeding has experienced a rise in popularity and is recommended to mothers during pregnancy and as part of contraception education. Anecdotal beliefs regarding the beneficial effects of breastfeeding on children’s overall psychological wellbeing have become a subject of scientific investigation. Within the current pregnancy-related standards, the modern promotion of breastfeeding encompasses nutritional, immunological and psychological aspects. In this paper we have summarized the evolution of the beliefs that have surrounded breastfeeding from antiquity to the present day.
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Costa, Maria Laura, Renato T. Souza, Rodolfo C. Pacagnella, Silvana F. Bento, Carolina C. Ribeiro-do-Valle, Adriana G. Luz, Giuliane J. Lajos, et al. "Brazilian network of COVID-19 during pregnancy (REBRACO: a multicentre study protocol)." BMJ Open 11, no. 12 (December 2021): e051284. http://dx.doi.org/10.1136/bmjopen-2021-051284.
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IntroductionThe aim of this study was to evaluate the clinical, epidemiological and laboratory aspects of SARS-CoV-2 infection during pregnancy and postpartum in 16 maternity hospitals.Methods and analysisA prospective multicentre study, with five axes. First, the prevalence of SARS-CoV-2 infection among women admitted for childbirth will be described in a cross-sectional study. Second, maternal and perinatal outcomes will be assessed in a prospective cohort study including pregnant or postpartum women with suspected COVID-19. Third, a cohort of positive COVID-19 cases with sampling of a variety of biological material. Histopathological and viral analysis of biological maternal and neonatal samples will be performed, and the assessment of nutritional variables to evaluate the association between vitamin D and severity of infection. Fourth, a monitoring and evaluation committee to collect relevant healthcare information and plan actions in centres facing the pandemic. Furthermore, qualitative studies will be performed to study pregnant women, their families and health professionals. Fifth, an ecological study will monitor the number of live births, stillbirths and other outcomes to explore any trend among the periods before, during and after the pandemic. Data will systematically be collected in an electronic platform following standardised operational procedures. For quantitative study components, an appropriate statistical approach will be used for each analysis. For qualitative data, in-depth interviews recorded in audio will be transcribed, checking the text obtained with the recording. Subsequently, thematic analysis with the aid of the NVivo programme will be performed.Ethics and disseminationEthical approval was obtained (letters of approval numbers 4.047.168, 4.179.679 and 4.083.988). All women will be fully informed to sign the consent form before enrolment in the study. Findings will be disseminated through peer-reviewed journals and scientific conferences.
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Chandra, Bastian Rahmadi, Rudi Saprudin Darwis, and Sahadi Humaedi. "PERAN PEMBERDAYAAN KESEJAHTERAAN KELUARGA (PKK) DALAM PENCEGAHAN STUNTING." Focus : Jurnal Pekerjaan Sosial 4, no. 2 (February 1, 2022): 107. http://dx.doi.org/10.24198/focus.v4i2.35060.
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Balita stunting dipahami sebagai balita yang mengalami permasalahan kondisi gizi kronis, kondisi tersebut dipengaruhi oleh banyak faktor yang meliputi keadaan sosial dan perekonomian orang tua, asupan nutrisi atau gizi saat masa kehamilan, riwayat penyakit yang dialami bayi, dan kurangnya nutrisi atau gizi pada bayi serta pola asuh yang tidak sesuai dengan pertumbuhan dan perkembangan anak, terlebih pada masa 1.000 HPK. Dalam jangka pendek akan berdampak pada terpengaruhinya beberapa aspek seperti aspek kognitif, aspek motorik, dan aspek verbal yang mengalami hambatan. Dalam jangka yang panjang stunting menyebabkan kondisi perawakan pada balita kurang proporsional pada usia remaja menuju dewasa. Stunting juga meningkatkan resiko obesitas di masa yang akan mendatang. Stunting juga berdampak pada kesehatan reproduksi yang menurun. Anak stunting juga memiliki penurunan kapasitas belajar, sehingga performa dan produktivitasnya di sekolah akan berkurang dan tidak optimal. Pelaksanaan intervensi sensitive dilakukan lebih berfokus pada penanganan faktor-faktor yang secara tidak langsung mempengaruhi kondisi asupan gizi yang menyumbang terjadinya stunting. Intervensi gizi sensitif memiliki sumbangsih yang signifikan yaitu sebesar 70 % dalam upaya pencegahan terjadinya stunting meskipun secara tidak langsung. Pemberdayaan kesejahteraan keluarga (PKK) berperan sebagai agen perubahan untuk melaksanakan pemberdayaan masyarakat agar tujuan pembangunan kesehatan dapat tercapai. Tujuan tersebut ialah untuk meningkatkan kesadaran masyarakat tentang issue stunting dan menangani kasus stunting dengan pelaksanaan pemberdayaan masyarakat oleh kelompok pemberdayaan kesejahteraan keluarga (PKK). Stunting toddlers are understood as toddlers who experience problems with chronic nutritional conditions, these conditions are influenced by many factors including the social and economic conditions of parents, nutritional intake or nutrition during pregnancy, history of illness experienced by infants, and lack of nutrition or nutrition in infants and patterns of nutrition. parenting that is not in accordance with the growth and development of children, especially during the 1,000 HPK period. In the short term, it will affect several aspects such as cognitive aspects, motor aspects, and verbal aspects that experience obstacles. In the long term, stunting causes stature conditions in toddlers to be less proportional from adolescence to adulthood. Stunting also increases the risk of obesity in the future. Stunting also has an impact on declining reproductive health. Stunting children also have a decreased learning capacity, so their performance and productivity in school will be reduced and not optimal. The implementation of sensitive interventions is carried out more focused on handling factors that indirectly affect the condition of nutritional intake that contributes to stunting. The sensitive nutrition intervention has a significant contribution of 70% in preventing stunting even though it is indirectly. Family Welfare Empowerment (PKK) acts as an agent of change to implement community empowerment so that health development goals can be achieved. The aim is to increase public awareness about the stunting issue and handle stunting cases by implementing community empowerment by the Family Welfare Empowerment Group (PKK).
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Arnould, J. P. Y., I. L. Boyd, and R. M. Warneke. "Historical dynamics of the Australian fur seal population: evidence of regulation by man?" Canadian Journal of Zoology 81, no. 8 (August 1, 2003): 1428–36. http://dx.doi.org/10.1139/z03-134.
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The Australian fur seal (Arctocephalus pusillus doriferus) was severely over-exploited in the 18th and 19th centuries and until relatively recently its population had remained steady at well below estimated presealing levels. However, the population is now increasing rapidly (6%20% per annum) throughout its range and there is a need to understand its dynamics in order to assess the potential extent and impact of interactions with fisheries. Age distribution (n = 156) and pregnancy rate (n = 110) were determined for adult females collected at a breeding colony on Seal Rocks, southeast Australia, in 19711972. Mean ± SE and maximum observed ages were 9.37 ± 0.41 and 20 years (n = 1), respectively. A stochastic modelling approach was used to fit an age distribution to the observed age-structure data and calculate rates of recruitment and adult survival. Annual adult female survival and recruitment rates between 1954 and 1971 were 0.478 ± 0.029 (mean ± SE) and 0.121 ± 0.007, respectively, suggesting that the population was experiencing a decline during the 1960s. The pregnancy rate increased from 78% at 3 years of age to an average of 85% between 413 years of age before significantly decreasing in older females (the oldest was 19 years of age). There was no significant effect of body mass or condition on the probability of a female being pregnant (P > 0.5 in both cases) and the nutritional burden of lactation did not appear to affect pregnancy rates or gestational performance. These findings suggest that the low survivorship was due to density-independent effects such as mortality resulting from interactions with fishers, which are known to have been common at the time. The recent increase in the population is consistent with anecdotal evidence that such interactions have decreased as fishing practices have changed.
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Croker, KP, MA Johns, SH Bell, GA Brown, and JF Wallace. "The influence of vaccination with Fecundin and supplementation with lupin grain on the reproductive performance of Merino ewes in Western Australia." Australian Journal of Experimental Agriculture 30, no. 4 (1990): 469. http://dx.doi.org/10.1071/ea9900469.
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The reproductive performances of groups of 4-6-year-old medium wool Merino ewes that were vaccinated with Fecundin and/or fed sweet lupin grain prior to and during the early part of the joining period were compared with untreated ewes over 2 years. The rams were joined with the ewes in early January of each year. In both years the Fecundin and lupin treatments increased ovulation rates (between 0.13 and 0.56) and the incidence of multiple pregnancies (between 1 and 36%). The proportions of lambs born following treatment with Fecundin were larger than those from the ewes fed only lupins. When the treatments were combined, there were no increases in lambs born above that of Fecundin alone. Pregnancy significantly depressed wool production from individual ewes, while those with more than 1 lamb produced less wool than those with only 1 lamb. However, the average quantity (4.6 kg greasy) and quality of wool produced by the ewes each year was similar for all groups, indicating that the variation in the incidence of multiple pregnancies had not affected flock wool production. The average rate of growth of the progeny from marking to weaning was also similar for each group (191 and 238 g/head.day for years 1 and 2, respectively) even though there were more multiple-born lambs in the Fecundin-treated groups. On a flock basis, it would appear that the nutritional conditions experienced during this study were adequate to avoid significant penalties associated with multiple pregnancies.
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Maani Hessari, Nason, May van Schalkwyk, Sian Thomas, and Mark Petticrew. "Alcohol Industry CSR Organisations: What Can Their Twitter Activity Tell Us about Their Independence and Their Priorities? A Comparative Analysis." International Journal of Environmental Research and Public Health 16, no. 5 (March 12, 2019): 892. http://dx.doi.org/10.3390/ijerph16050892.
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There are concerns about the accuracy of the health information provided by alcohol industry (AI)-funded organisations and about their independence. We conducted a content analysis of the health information disseminated by AI-funded organisations through Twitter, compared with non-AI-funded charities, to assess whether their messages align with industry and/or public health objectives. We compared all tweets from 2016 from Drinkaware (UK); Drinkaware.ie (Ireland); and DrinkWise (Australia), to non-AI-funded charities Alcohol Concern (UK), Alcohol Action Ireland, and FARE (Australia). Industry-funded bodies were significantly less likely to tweet about alcohol marketing, advertising and sponsorship; alcohol pricing; and physical health harms, including cancers, heart disease and pregnancy. They were significantly more likely to tweet about behavioural aspects of drinking and less likely to mention cancer risk; particularly breast cancer. These findings are consistent with previous evidence that the purpose of such bodies is the protection of the alcohol market, and of the alcohol industry’s reputation. Their messaging strongly aligns with AI corporate social responsibility goals. The focus away from health harms, particularly cancer, is also consistent with previous evidence. The evidence does not support claims by these alcohol-industry-funded bodies about their independence from industry.
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Weston, RH. "Some aspects of constraint to forage consumption by ruminants." Australian Journal of Agricultural Research 47, no. 2 (1996): 175. http://dx.doi.org/10.1071/ar9960175.
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Various aspects of forage intake regulation are discussed with the objective of providing a basis on which assessments could be made of (i) the scope for forage intake manipulation, and (ii) priority areas for further research. A simple conceptual model of the regulation is presented which permits the linking of rumen function and energy metabolism. It takes cognizance of upper physiological limits for (i) energy disposal, (ii) the clearance of digesta organic matter from the rumen, and (iii) muscular fatigue, as well as a range of dietary and environmental constraints. The transmission to the brain of signals relating to amount of digesta in the rumen and the ruminant's energy deficit are considered to be important in the intake regulation. An alternative conceptual model which recognises the amount of energy in the circulating energy pool, rather than the energy deficit, as the origin of signals relating to energy metabolism, is also discussed. It is considered that over a range of forage qualities neither the rumen digesta load ceiling nor the capacity to use energy limit intake; in this range both the resistance of the forage organic matter to removal from the rumen and the net energy value of the forage act as constraints. A method to calculate forage intake constraint is presented, and theoretical relationships between rumen digesta load, net energy intake, energy deficit and forage intake constraint have been formulated to facilitate interpretation of data obtained in forage intake studies. Forage intake in the reproduction cycle is discussed in the context of an optimum nutritional strategy for ensuring species survival. It is considered that the intake changes at mating and immediately prior to parturition, together with the decrease in rate of nutrient storage in maternal reserve tissues in late pregnancy and the use of these tissue stores in early lactation, are consistent with such a strategy. In this context it is suggested that (i) the relevant reproduction hormones affect intake via modulation of the metabolism of the maternal tissue stores and (ii) this type of regulation and its accompanying production losses need not be necessary in those production systems permitting some control of nutrition.
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Yajnik, C. S. "Obesity epidemic in India: intrauterine origins?" Proceedings of the Nutrition Society 63, no. 3 (August 2004): 387–96. http://dx.doi.org/10.1079/pns2004365.
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The epidemic of ‘obesity’ in India is not appreciated because BMI underestimates the adiposity of Indians. Specific adiposity measurements are necessary for recognition of the adiposity of ‘thin’ Indians. The origin of this adiposity is only beginning to be understood. In addition to a possible genetic predisposition, intrauterine ‘programming’ might be responsible, although in the ‘thrifty phenotype’ hypothesis the adiposity of the ‘thin’ fetus has not been appreciated. Dutch men who faced ‘winter hunger’ during the first trimester of their in utero life have become more obese as adults. Low birth weight predicts central obesity in some studies, including studies in urban children. It has also been shown that small and thin Indian newborns (weight 2·7?kg and ponderal index 2·4?kg\m3) have poor muscle and visceral mass but higher adiposity for a given weight compared with white Caucasian babies. This body composition is influenced by maternal adiposity before pregnancy and by aspects of maternal nutritional intake and circulating nutrient concentrations during pregnancy. There are no strong paternal determinants of adiposity at birth. Adiposity may be an integral part of the orchestrated adjustments made to support ‘brain preservation’ during intrauterine growth, because brain tissue is predominantly fat. Increased nutrition in the face of a genetic predisposition or multigenerational undernutrition increases maternal insulin resistance in late pregnancy and promotes fetal adiposity even in absence of marked hyperglycaemia. Further research is necessary to define the role of specific nutrients and metabolites in the intrauterine processes promoting adiposity before maternal interventions to curtail the epidemic of obesity and diabetes are planned.
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Spencer, Sarah J., Abdeslam Mouihate, Michael A. Galic, Shaun L. Ellis, and Quentin J. Pittman. "Neonatal immune challenge does not affect body weight regulation in rats." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 293, no. 2 (August 2007): R581—R589. http://dx.doi.org/10.1152/ajpregu.00262.2007.
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The perinatal environment plays a crucial role in programming many aspects of adult physiology. Myriad stressors during pregnancy, from maternal immune challenge to nutritional deficiency, can alter long-term body weight set points of the offspring. In light of the increasing concern over body weight issues, such as obesity and anorexia, in modern societies and accumulating evidence that developmental stressors have long-lasting effects on other aspects of physiology (e.g., fever, pain), we explored the role of immune system activation during neonatal development and its impact on body weight regulation in adulthood. Here we present a thorough evaluation of the effects of immune system activation (LPS, 100 μg/kg ip) at postnatal days 3, 7, or 14 on long-term body weight, adiposity, and body weight regulation after a further LPS injection (50 μg/kg ip) or fasting and basal and LPS-induced circulating levels of the appetite-regulating proinflammatory cytokine leptin. We show that neonatal exposure to LPS at various times during the neonatal period has no long-term effects on growth, body weight, or adiposity. We also observed no effects on body weight regulation in response to a short fasting period or a further exposure to LPS. Despite reductions in circulating leptin levels in response to LPS during the neonatal period, no long-term effects on leptin were seen. These results convincingly demonstrate that adult body weight and weight regulation are, unlike many other aspects of adult physiology, resistant to programming by a febrile-dose neonatal immune challenge.
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Danaah Malick, Martin Mumuni, Aloysius Maalekuu, and Odalys Hernandez Rivera. "Prevalence and Factors Associated with Anemia in Pregnancy among Women Receiving Antenatal Care at the West Gonja District Hospital of Northern Ghana." International Journal of Innovative Research in Medical Science 5, no. 08 (August 1, 2020): 271–83. http://dx.doi.org/10.23958/ijirms/vol05-i08/915.
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Background: Anemia in pregnancy is a major public health problem especially in Low and Middle-income countries (LMIC) including Ghana and is defined by the World Health Organization (WHO) as being present when the hemoglobin concentration in the peripheral blood is 11g/dl or less. In most African countries anemia in pregnancy occurs if the hemoglobin concentration falls below 10g/dl. Pregnant women are at a higher risk of developing anemia due to several factors such as hemodilution, nutritional factors, multiple gestation, socio-economic status and malaria infestation. Anemia in pregnancy is an important cause of maternal mortality and affects half of pregnant women worldwide; with 56% of West African pregnant women being anemic. The objective of this study is to assess the prevalence and identify the risk factors associated with anemia among pregnant women receiving antenatal care at the West Gonja Hospital(WGH) Methods: A cross-sectional was conducted with 136 pregnant women receiving antenatal care at the WGH between January 2017 to February 2018. Random sampling was used to select participants and data was collected using a structured questionnaire. Data was analyzed using the SPSS Version 24.0. Results: A total 71(52.2%) of the study population were anemic, while 65 (47.8%) were not anemic. 20(74.1%) of the 27 pregnant housewives were anemic, while 11(64.7%) of the pregnant farmers were anemic. 27 (96.4%) of the 28 pregnant women who took their iron/folate supplement only some few days were anemic. 12 (100%) of the 12 participants who took their iron/folate supplement a few times a week were anemic. 4 (80%) of the 5 participants who never took their iron/folate supplement were anemic. 21 (70%) of those who did not sleep under ITN were anemic. 33 (84.6%) of the 39 patients who were diagnosed with malaria were also anemic. 28 (87.5%) of the 32 participants who took only 2 meals a day were anemic. 27 (79.4%) of the 34 patients who took liver, beef, chicken and fish only twice weekly were anemic. 15 (88.2%) of the 17 patients who drank tea some days in a week were anemic. Conclusion: Although most of the pregnant women were adequately educated on the most relevant aspects of anemia in pregnancy, more than half of them were still anemic. Anemia was more prevalent among pregnant uneducated housewives with poor nutritional habits. All the pregnant sickle cell disease patients as well as those diagnosed with malaria were also anemic.
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Malick, Martin. "Prevalence and factors associated with anemia in pregnancy among women receiving antenatal care at the West Gonja District Hospital of Northern Ghana." Obstetrics Gynecology and Reproductive Sciences 4, no. 3 (December 14, 2020): 01–12. http://dx.doi.org/10.31579/2578-8965/042.
Full textAbstract:
Background: Anemia in pregnancy is a major public health problem especially in Low and Middle-income countries (LMIC) including Ghana and is defined by the World Health Organization (WHO) as being present when the hemoglobin concentration in the peripheral blood is 11g/dl or less. In most African countries anemia in pregnancy occurs if the hemoglobin concentration falls below 10g/dl. Pregnant women are at a higher risk of developing anemia due to several factors such as hemodilution, nutritional factors, multiple gestation, socio-economic status and malaria infestation. Anemia in pregnancy is an important cause of maternal mortality and affects half of pregnant women worldwide; with 56% of West African pregnant women being anemic. The objective of this study is to assess the prevalence and identify the risk factors associated with anemia among pregnant women receiving antenatal care at the West Gonja Hospital (WGH) Methods: A cross-sectional was conducted with 136 pregnant women receiving antenatal care at the WGH between January 2017 to February 2018. Random sampling was used to select participants and data was collected using a structured questionnaire. Data was analyzed using the SPSS Version 24.0. Results: A total 71(52.2%) of the study population were anemic, while 65 (47.8%) were not anemic. 20(74.1%) of the 27 pregnant housewives were anemic, while 11(64.7%) of the pregnant farmers were anemic. 27 (96.4%) of the 28 pregnant women who took their iron/folate supplement only some few days were anemic. 12 (100%) of the 12 participants who took their iron/folate supplement a few times a week were anemic. 4 (80%) of the 5 participants who never took their iron/folate supplement were anemic. 21 (70%) of those who did not sleep under ITN were anemic. 33 (84.6%) of the 39 patients who were diagnosed with malaria were also anemic. 28 (87.5%) of the 32 participants who took only 2 meals a day were anemic. 27 (79.4%) of the 34 patients who took liver, beef, chicken and fish only twice weekly were anemic. 15 (88.2%) of the 17 patients who drank tea some days in a week were anemic. Conclusion: Although most of the pregnant women were adequately educated on the most relevant aspects of anemia in pregnancy, more than half of them were still anemic. Anemia was more prevalent among pregnant uneducated housewives with poor nutritional habits. All the pregnant sickle cell disease patients as well as those diagnosed with malaria were also anemic.