To see the other types of publications on this topic, follow the link: PPBS.
Journal articles on the topic 'PPBS'
Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles
Consult the top 50 journal articles for your research on the topic 'PPBS.'
Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.
You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.
Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.
1
Norgren, R., O. Björkqvist, and A. Jonsson. "Bio-sludge from the Pulp and Paper Industry as Feed for Black Soldier Fly Larvae: A Study of Critical Factors for Growth and Survival." Waste and Biomass Valorization 11, no. 11 (October 31, 2019): 5679–85. http://dx.doi.org/10.1007/s12649-019-00864-x.
Full textAbstract:
Abstract Pulp and paper bio-sludge (PPBS) has low economic value and is therefore often composted or incinerated. The purpose of this work is to evaluate the feasibility of using PPBS to breed black soldier fly (Hermetia illucens) larvae (BSFL), so improving resource efficiency and supplying protein and fat to the animal feed market. BSFL were reared on PPBS in a climate chamber on a laboratory scale in order to assess nutrient deficiency, inhibition and whether the BSFL recycle the PPBS well or not. The PPBS used came from a chemi-thermomechanical pulp/groundwood pulp mill. The effect of supplementing nutrient solution added either into the PPBS or as a free liquid surface were studied. Prepupae dry weight, survival rate until prepupae stage and residual dry PPBS were measured. The addition of reference diet leachate into the PPBS did not have a significant impact on the weight of the prepupae (2.0 mg) but the survival rate was significantly higher (16.0%). On the other hand, the addition of reference diet leachate as a free liquid surface had a significant impact on both the weight of the prepupae (4.8 mg) and the survival rate (25.7%). The bio-conversion and PPBS—reduction was as best 0.4 and 3.2% respectively. This study has proven that the nutrients in PPBS are not readily available to the larvae. Addition of reference diet leachate increase the survival rate which opens up for possibilities of co-digestion. However, it is clear that under the tested conditions, BSFL is not recycling PPBS well and BSFL as a method for recycling of PPBS need further research. Graphic Abstract
2
WANG, HONG, ADRIAN J. CUTLER, and LARRY C. FOWKE. "High Frequencies of Preprophase Bands in Soybean Protoplast Cultures." Journal of Cell Science 92, no. 4 (April 1, 1989): 575–80. http://dx.doi.org/10.1242/jcs.92.4.575.
Full textAbstract:
Protoplasts derived from a non- regenerable soybean cell line provide an excellent experimental system for studying plant preprophase bands (PPBs). Cultured protoplasts developed PPBs in high frequencies, permitting a detailed analysis of PPB development. From observations of thousands of PPBs, six distinct developmental stages were identified. This classification should prove useful in recognizing developmental stages of PPBs and in comparing results among different tissues and species. Perinuclear fluorescence appeared when PPBs were well developed. It consisted of microtubule strands radiating from the nuclear surface at its early stages and more extensive arrays on the surface at later stages. All protoplast cultures from 0.5 day to 5 days had a PPB index (ratio between number of PPBs and number of phragmoplasts) greater than unity, suggesting that in this cell line a high frequency of PPBs is apparently not related to the potential for organized growth (e.g. embryogenesis). Different methods of quantifying the occurrence of PPBs were evaluated. The PPB value (ratio between % of cells with PPB and the mitotic index) was compared with the PPB index and results indicate that it is a useful new parameter for studies of the distribution of PPBs in plant cells.
3
Cook, W. R. "Whatever Happened to PPBS?" International Review of Administrative Sciences 52, no. 2 (June 1986): 223–41. http://dx.doi.org/10.1177/002085238605200207.
Full text
4
Alain, Alaa Mohama Malo, and Magdy Melegy Abdul Hakim Melegy. "Program and Performance Budgeting System in Public Sector Organizations: An Analytical Study in Saudi Arabian Context." International Business Research 10, no. 4 (March 24, 2017): 157. http://dx.doi.org/10.5539/ibr.v10n4p157.
Full textAbstract:
In order to improve the budget system, a number of approaches and techniques have been adopted in public sector organizations such as Program and Performance Budgeting System (PPBS), Performance Based Budgeting System (PBBS) and Zero-Based Budgeting (ZBB). The present study is an extension in the line of very few researches which had been conducted in developing countries in regard to implementation of “One Budgetary Approach” which is known as “Program and Performance Budgeting System PPBS”. The study concentrates its focus on the support which it may find in case of “budgetary format” is adopted by the “Public Sector Organizations” in the kingdom of Saudi Arabia. The study explores several dimensions such as familiarity, acceptability and adoptability of PPBS, “degree of contribution of Accounting System followed by “public sector organizations” to adopt PPBS”, the benefits that might be realized and the obstacles that probably might be faced if this approach of budgeting is adopted by Public Sector Organizations” in Al-Kharj region. The study came up with the following main findings; there is a fair familiarity and understanding of PPBS by financial managers and accountants working in the “public sector organizations”, the accounting system followed by “public sector organizations” contributes to adopt PPBS successfully, there are certain benefits could be obtained while adopting PPBS by public sector organizations, and finally certain obstacles have been discovered which are standing as stumbling-stone to adopt PPBS in “public sector organizations” in Al-Kharj region effectively.
5
Bainbridge, Timothy F., Joshua A. Quinlan, Raymond A. Mar, and Luke D. Smillie. "Openness/Intellect and Susceptibility to Pseudo–Profound Bullshit: A Replication and Extension." European Journal of Personality 33, no. 1 (January 2019): 72–88. http://dx.doi.org/10.1002/per.2176.
Full textAbstract:
‘Pseudo–profound bullshit’ (PPBS) is a class of meaningless statements designed to appear profound. Profundity ratings for PPBS have been found to be negatively related to analytical thinking and positively related to epistemically suspect beliefs (e.g. belief in the paranormal). Conceptually similar traits within the Openness/Intellect (O/I) domain form a simplex, whereby traits are arranged along a single dimension from intelligence to apophenia (i.e. observing patterns or causal connections were none exist). Across two studies (total N = 297), we attempted to replicate the O/I simplex and determine how it relates to perceiving PPBS as profound. Participants completed questionnaires measuring traits from the O/I simplex and provided profundity ratings for PPBS. Profundity ratings of PPBS tended to correlate negatively with intelligence and positively with apophenia. The association with intelligence generally reflected a greater ability to discriminate the profound from the pseudo–profound, whereas the association with apophenia reflected poorer discrimination in Study 1, with less conclusive results in Study 2. In both studies, the O/I simplex was closely replicated. The results suggest a link between the O/I domain and perceiving PPBS as profound and tentatively support the theory that intelligence may protect against apophenia. © 2018 European Association of Personality Psychology
6
Van Loenhout, Jinthe, Tal Flieswasser, Laurie Freire Boullosa, Jorrit De Waele, Jonas Van Audenaerde, Elly Marcq, Julie Jacobs, et al. "Cold Atmospheric Plasma-Treated PBS Eliminates Immunosuppressive Pancreatic Stellate Cells and Induces Immunogenic Cell Death of Pancreatic Cancer Cells." Cancers 11, no. 10 (October 19, 2019): 1597. http://dx.doi.org/10.3390/cancers11101597.
Full textAbstract:
Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive cancers with a low response to treatment and a five-year survival rate below 5%. The ineffectiveness of treatment is partly because of an immunosuppressive tumor microenvironment, which comprises tumor-supportive pancreatic stellate cells (PSCs). Therefore, new therapeutic strategies are needed to tackle both the immunosuppressive PSC and pancreatic cancer cells (PCCs). Recently, physical cold atmospheric plasma consisting of reactive oxygen and nitrogen species has emerged as a novel treatment option for cancer. In this study, we investigated the cytotoxicity of plasma-treated phosphate-buffered saline (pPBS) using three PSC lines and four PCC lines and examined the immunogenicity of the induced cell death. We observed a decrease in the viability of PSC and PCC after pPBS treatment, with a higher efficacy in the latter. Two PCC lines expressed and released damage-associated molecular patterns characteristic of the induction of immunogenic cell death (ICD). In addition, pPBS-treated PCC were highly phagocytosed by dendritic cells (DCs), resulting in the maturation of DC. This indicates the high potential of pPBS to trigger ICD. In contrast, pPBS induced no ICD in PSC. In general, pPBS treatment of PCCs and PSCs created a more immunostimulatory secretion profile (higher TNF-α and IFN-γ, lower TGF-β) in coculture with DC. Altogether, these data show that plasma treatment via pPBS has the potential to induce ICD in PCCs and to reduce the immunosuppressive tumor microenvironment created by PSCs. Therefore, these data provide a strong experimental basis for further in vivo validation, which might potentially open the way for more successful combination strategies with immunotherapy for PDAC.
7
Balint, Istvan Bence, Ferenc Csaszar, Krisztian Somodi, Laszlo Ternyik, Adrienn Biro, and Zsolt Kaposztas. "Is duodeno-jejunal bypass liner superior to pylorus preserving bariatric surgery in terms of complications and efficacy?" Langenbeck's Archives of Surgery 406, no. 5 (March 12, 2021): 1363–77. http://dx.doi.org/10.1007/s00423-021-02131-x.
Full textAbstract:
Abstract Purpose Based on recent scientific evidence, bariatric surgery is more effective in the management of morbid obesity and related comorbidities than conservative therapy. Pylorus preserving surgical procedures (PPBS) such as laparoscopic single-anastomosis duodeno-jejunal or duodeno-ileal bypass with sleeve gastrectomy are modified duodenal switch (DS) surgical techniques. The duodeno-jejunal bypass liner (DJBL) is a novel surgical method in the inventory of metabolism focused manual interventions that excludes duodeno-jejunal mucosa from digestion, mimicking DS procedures without the risk of surgical intervention. The aim of this article is to summarize and compare differences between safety-related features and weight loss outcomes of DJBL and PPBS. Methods A literature search was conducted in the PubMed database. Records of DJBL-related adverse events (AEs), occurrence of PPBS-related complications and reintervention rates were collected. Mean weight, mean body mass index (BMI), percent of excess of weight loss (EWL%), percent of total weight loss (TWL%) and BMI value alterations were recorded for weight loss outcomes. Results A total of 11 publications on DJBL and 6 publications on PPBS were included, involving 800 and 1462 patients, respectively. The baseline characteristics of the patients were matched. Comparison of DJBL-related AEs and PPBS-related severe complications showed an almost equal risk (risk difference (RD): −0.03 and confidence interval (CI): −0.27 to 0.21), despite higher rates among patients having received endoscopic treatment. Overall AE and complication rates classified by Clavien-Dindo showed that PPBS was superior to DJBL due to an excess risk level of 25% (RD: 0.25, CI: 0.01–0.49). Reintervention rates were more favourable in the PPBS group, without significant differences in risk (RD: −0.03, CI: −0.27 to 0.20). However, PPBS seemed more efficient regarding weight loss outcomes at 1-year follow-up according to raw data, while meta-analysis did not reveal any significant difference (odds ratio (OR): 1.08, CI: 0.74–1.59 for BMI changes). Conclusion Only limited conclusions can be made based on our findings. PPBS was superior to DJBL with regard to safety outcomes (GRADE IIB), which failed to support the authors’ hypothesis. Surgical procedures showed lower complication rates than the incidence of DJBL-related AEs, although it should be emphasized that the low number of PPBS-related mild to moderate complications reported could be the result of incomplete data recording from the analysed publications. Weight loss outcomes favoured bariatric surgery (GRADE IIB). As the DJBL is implanted into the upper gastrointestinal tract for 6 to 12 months, it seems a promising additional method in the inventory of metabolic interventions.
8
Neelam, Ameera, and Anand Kanaki. "Efficacy and safety of remogliflozin etabonate in type 2 diabetes mellitus patients in a tertiary care hospital." International Journal of Basic & Clinical Pharmacology 10, no. 4 (March 22, 2021): 353. http://dx.doi.org/10.18203/2319-2003.ijbcp20211014.
Full textAbstract:
Background: Incidence and prevalence of diabetes have been steadily increasing with a raise of global prevalence about 8.5%. The major types of diabetes are differentiated by insulin deficiency versus insulin resistance. SGLT2 inhibitors are a new class of drugs that act by inhibiting glucose reabsorption in the proximal renal tubules. Remogliflozin a prodrug of remogliflozin, which is a potent and selective sodium-glucose co-transporter-2 inhibitor was used for the study. The objective of the study was to evaluate the efficacy and safety of Remogliflozin etabonate in reducing HbA1C and serum glucose in type II diabetics.Methods: This was a prospective observational study was done for 3 months. HbA1C, FBS and PPBS readings were noted and then the subjects were introduced to Remoglifozin 100 mg twice a day. At the end of 12 weeks HbA1C, FBS and PPBS were noted. The obtained data was analysed for its efficacy and safety.Results: The study included 22 male subjects and 28 females. Before Remoglifzoin was given the mean HbA1C level was 8.23± 0.798, mean FBS was 179± 29.79 and PPBS was 299.38± 24.21. Remoglifozin 100 mg was given and the mean HbA1C level was 7.52± 0.765, mean FBS was 166.30± 32.13 and mean PPBS was 249.46± 18.21. Post 3 months of Remoglifzoin induction a reduction in HbA1C, FBS and PPBS was seen.Conclusions: This study concludes Remoglifozin etabonate of 100 mg when given twice daily reduced the HbA1C levels, FBS and PPBS levels significantly.
9
Bavin, Edith L., Julia Sarant, Luke Prendergast, Peter Busby, Greg Leigh, and Candida Peterson. "Positive Parenting Behaviors: Impact on the Early Vocabulary of Infants/Toddlers With Cochlear Implants." Journal of Speech, Language, and Hearing Research 64, no. 4 (April 14, 2021): 1210–21. http://dx.doi.org/10.1044/2020_jslhr-20-00401.
Full textAbstract:
Purpose To extend our knowledge about factors influencing early vocabulary development for infants with cochlear implants (CIs), we investigated the impact of positive parenting behaviors (PPBs) from the Indicator of Parent Child Interaction, used in parent–child interactions during everyday activities. Method Implantation age for the sample recruited from CI clinics in Australia ranged from 6 to 10 months for 22 children and from 11 to 21 months for 11 children. Three observation sessions at three monthly intervals were coded for use of PPBs. Children's productive vocabulary, based on the MacArthur–Bates Communicative Development Inventories parent checklist, was collected approximately 6 and 9 months later. A repeated-measures negative binomial generalized linear mixed-effects model was used to investigate associations between the total PPBs per session, covariates (maternal education, gender, and time since implant), and the number of words produced. In follow-up analyses with the PPBs entered separately, variable selection was used to retain only those deemed informative, based on the Akaike information criterion. Results As early as Session 1, associations between the PPBs and vocabulary were identified. Time since implant had a positive effect. For different sessions, specific PPBs (descriptive language, follows child's lead, and acceptance and warmth) were identified as important contributors. Conclusions Complementing previous findings, valuable information was identified about parenting behaviors that are likely to impact positively the early vocabulary of infants with CIs. Of importance is providing parents with information and training in skills that have the potential to help create optimal contexts for promoting their child's early vocabulary development.
10
Jindal, Himanshu, Abhilasha Singh, Rajan Goyal, and Abhishek Kamendu. "Observational Study of Serum Alanine Aminotransferase (ALT), Serum Aspartate Aminotransferase (AST) and Serum Alkaline Phosphatase (ALP) Levels in Type 2 Diabetic Patients." Journal of Evidence Based Medicine and Healthcare 7, no. 48 (November 30, 2020): 2852–55. http://dx.doi.org/10.18410/jebmh/2020/584.
Full textAbstract:
BACKGROUND The relationship between liver enzymes like alanine aminotransferase (ALT), aspartate aminotransferase (AST), Alkaline phosphatase (ALP) and diabetes has been studied, but the results of these are inconsistent. Several prospective studies have reported that ALT was associated with incident diabetes. We wanted to study the levels of serum alanine aminotransferase (ALT), serum aspartate aminotransferase (AST) and serum alkaline phosphatase (ALP) in patients of Type 2 DM. METHODS This is a hospital based observational study which was conducted in Narayan Medical College and Hospital, Jamuhar, Sasaram, Rohtas, Bihar. Alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), glycosylated haemoglobin (HbA1c), FBS, PPBS, total bilirubin, and hepatitis B surface antigen (HBsAg) were determined in all study participants. RESULTS The mean value was 96.35, 67.37, 152.78 and 1.098 for AST, ALT, ALP and total bilirubin. On multivariate analysis for effect of FBS, PPBS, HbA1c on the value of AST weak correlation was found with R square of 0.11. On the effect of FBS, PPBS, HbA1c on the value of ALT we found weak correlation with an R square of 0.079. CONCLUSIONS There is a weak correlation between deranged liver enzyme (AST, ALT and ALP) with HbA1c, FBS and PPBS. But still, liver functions should be monitored in diabetic patients. KEYWORDS ALT, AST, Diabetes, HbA1c, FBS, PPBS
11
Nurlaeli, Acep. "PERENCANAAN PEMBIAYAAN BERBASIS PLANNING PROGRAMMING BUDGETTING SYSTEM (PPBS) DI SEKOLAH DASAR ISLAM TERPADU ANNI’MAH BANDUNG." Jurnal Isema : Islamic Educational Management 5, no. 1 (June 30, 2020): 29–40. http://dx.doi.org/10.15575/isema.v5i1.8912.
Full textAbstract:
Perencanaan pembiayan pendidikan yang baik berkontribusi terhadap mutu pengelolaan pendidikan. Perencanaan pembiayaan pendidikan merupakan total biaya yang dikeluarkan baik oleh individu peserta didik, keluarga yang menyekolahkan anak, warga masyarakat perorangan, kelompok masyarakat, maupun yang dikeluarkan oleh pemerintah untuk kelancaran pendidikan. Satuan pendidikan dituntut mampu menyusun perencanaan pembiayaan secara tepat. Permasalahan utama penelitian ini yaitu bahwa satuan pendidikan memerlukan adanya model perencanaan pembiayaan yang dipandang efektif. Penelitian ini bertujuan untuk menggambarkan perencanaan pembiayaan pendidikan Berbasis PPBS (Planning, Programming, Budgeting System). Penelitian menggunakan metode deskriptif kualitatif. Hasil penelitian menemukan bahwa Model PPBS (planning, programming, budgeting system) merupakan model perencanaan, penyusunan program dan penganggaran yang dipandang sebagai suatu sistem yang tak terpisahkan satu sama lainnya. Penelitian ini menyimpulkan bahwa perencanaan pembiayaan berbasis PPBS merupakan proses komprehensif dalam pengambilan keputusan karena model PPBS merupakan suatu pendekatan sistematik yang berusaha untuk menetapkan tujuan, mengembangkan program, menentukan besaran biaya, dan proses penganggaran yang merefleksikan kegiatan program jangka panjang. Perencanaan berbasis PPBS berkontribusi positif pada peningkatan mutu Sekolah Dasar (SD) Islam terpadu (IT) Anni’mah yang teridentifikasi ditandai adanya peningkatan mutu guru, meningkatnya mutu siswa, lingkungan belajar semakin kondusif, disiplin sekolah semakin baik, ketersediaan sumber belajar memadai, partisipasi orang tua meningkat, serta satuan biaya semakin terukur dengan jelas.Kata kunci: Perencanaan, Program, Budgeting Sistem
12
Bickel, Scott, Bethany Carnes, Matthew Thompson, Sheldon Bond, and Ronald Morton. "Type I Pleuropulmonary Blastoma Originating from an Extralobar Sequestration." European Respiratory & Pulmonary Diseases 02, no. 01 (2016): 23. http://dx.doi.org/10.17925/erpd.2016.02.01.23.
Full textAbstract:
Pleuropulmonary blastomas (PPBs) represent a rare, malignant neoplasm in infants and children. Despite their overall rarity, they are the most common primary lung malignancy in young children. Typically originating as cystic lesions that are amenable to easy resection, PPBs can progress to solid masses prone to metastases if not identified and treated early enough. In their early cystic form, PPBs are often difficult to distinguish from congenital pulmonary airway malformations based on clinical and radiographic findings. We report on an eight-month-old girl who presented to our institution with a large, right-sided, cystic lung lesion, which had not been apparent on a chest radiograph shortly after birth. After excision of the lesion, pathology demonstrated it to be a type I PPB, which was unique for its apparent extra lobar origin. We review the relevant literature concerning PPBs, as well as the debate surrounding resection of cystic lung lesions in infants and children.
13
Wildavsky, Aaron. "Sauver l'analyse de politique du PPBS." Politiques et management public 9, no. 4 (1991): 75–98. http://dx.doi.org/10.3406/pomap.1991.3027.
Full text
14
Kariyawasan, C. C., B. L. T. Balasuriya, S. A. C. D. Ranatunga, D. M. C. Dissanayake, and S. R. G. P. Herath. "The Association between Hba1c- Derived Estimated Average Glucose (Eag) with Fasting Blood Sugar (FBS) and Post Prandial Blood Sugar (PPBS) in Patients with Type 2 Diabetes in A Cohort of Patients in a Tertiary Care Hospital in Sri Lanka." European Journal of Medical and Health Sciences 3, no. 2 (April 8, 2021): 117–21. http://dx.doi.org/10.24018/ejmed.2021.3.2.761.
Full textAbstract:
Introduction: Type 2 Diabetes mellitus (T2DM) is a chronic illness, caused due to resistance to insulin or poor production. FBS, PPBS and Glycated Haemoglobin (HbA1c) are the major tests that are used to monitor chronic glycemia worldwide. HbA1c level remains the gold standard test for assessment of glycemic control at follow up and it reflects the mean glucose values in the previous three - month period. HbA1c is expressed as a percentage, whereas the day-to-day monitoring and treatment of diabetes are based on blood glucose levels expressed as milligrams per deciliter (mg/dl) or millimoles per liter (mmol/L). Due to the difference in the denominators of FBS/PPBS with HbA1c, it causes confusion to the patients regards their glycaemic control. “Estimated average glucose” or eAG derived from HbA1c has been promoted by the American Diabetes Association (ADA). American Association of Clinical Chemists concludes that the correlation (r =0.92) is strong enough to justify reporting both HbA1c and eAG which indicate the 3- month control of the average sugar of the patient. This is easy for the patient as both FBS/PPBS and eAG are expressed with the same denominator for daily glucose checks and long-term control respectively, enhancing the glycaemic control.
Objectives: To determine the statistical correlation between eAG derived from HBA1C using the Nathan’s regression equation with FBS and PPBS in patients with T2DM. To analyze the significance of eAG as opposed to HbA1C as a marker of long-term glycemic control in T2DM.
Methodology: A retrospective analytical study done at the Department of Haematology of the Sri Jayewardenepura General Hospital, Sri Lanka. A simple random sampling technique was used, over a period of one year commencing June 2019 to June 2020, to obtain the laboratory records through laboratory information system of 201 adult patients both males and females who were diagnosed with T2DM. HbA1c, FBS, PPBS done on the same day were recorded. The eAG(mg/dl) was calculated using the Nathan’s regression equation (eAG = 28.7 x HbA1c – 46.7). Three groups were generated according to the patients’ levels of FBS and PPBS.
Statistical Analysis: Data were double entered and analyzed using (SPSS) version 20. Descriptive statistical methods were used to calculate the median, mean standard deviation of age, HBA1c, FBS, and PPBS. Correlations between study variables were done with Pearson’s correlation method. The p value, lower than 0.05 was considered as statistically significant. Coefficient of determination (R Sq) was used to a statistical measure of how close the data are to the fitted regression line.
Results: The total population of patients in both the FBS and PPBS groups showed a significant statistical correlation with eAG. The individual subgroups did not conform to this correlation. The results reveal no statistical correlation in both FBS and PPBS with eAG in patients with good glycaemic control. There was a significant statistical correlation in both FBS and PPBS with eAG in the groups of patients with moderately poor control. In those with markedly poor control the FBS did not show a statistical correlation with eAG, as opposed to the PPBS.
Conclusion: The clinical importance of HbA1C/eAG in diagnosis and management of T2DM can be re-emphasized by this study. HbA1C along with eAG may be added as a test in the management of T2DM, for the better understanding and maintenance of good glycemic control. As eAG values, derived by the Nathan’s regression equation in our study scattered very close to the regression line, it provided a more complete and representative measure of average glucose in past 3 months. We conclude that HbA1c values were reliably translated into eAG measurements which would be easily understood by the patients being of the same denominator as the FBS/PPBS.
15
Tran, Quang Nhat, Benjamin P. Turnbull, Hao-Tian Wu, A. J. S. de Silva, Katerina Kormusheva, and Jiankun Hu. "A Survey on Privacy-Preserving Blockchain Systems (PPBS) and a Novel PPBS-Based Framework for Smart Agriculture." IEEE Open Journal of the Computer Society 2 (2021): 72–84. http://dx.doi.org/10.1109/ojcs.2021.3053032.
Full text
16
Fagerlind, Hanna, Åsa Kettis, Bengt Glimelius, and Lena Ring. "Barriers Against Psychosocial Communication: Oncologists' Perceptions." Journal of Clinical Oncology 31, no. 30 (October 20, 2013): 3815–22. http://dx.doi.org/10.1200/jco.2012.45.1609.
Full textAbstract:
Purpose To explore oncologists' psychosocial attitudes and beliefs and their perceptions regarding barriers against psychosocial communication. Methods A questionnaire was distributed to oncologists in Sweden (n = 537). Questions covered demography, the Physician Psychosocial Beliefs Scale (PPBS), and barriers against psychosocial communication. Stepwise multiple regression was used to determine what factors contribute the most to the PPBS score and the total number of barriers and barriers affecting clinical practice, respectively. Spearman rank-order correlation was used to determine correlation between PPBS score and number of barriers. Results Questionnaire response rate was 64%. Mean PPBS value was 85.5 (range, 49 to 123; SD, 13.0). Most oncologists (93%) perceived one or more barriers in communicating psychosocial aspects with patients. On average, five different communication barriers were perceived, of which most were perceived to affect clinical practice. These barriers included insufficient consultation time, lack of resources for taking care of problems discovered, and lack of methods to evaluate patients' psychosocial health in clinical practice. There was a positive correlation (rs = 0.490; P < .001) between the PPBS score and the number of perceived barriers (ie, less psychosocially oriented oncologists perceived more barriers). Oncologists with supplementary education with a psychosocial focus perceived fewer barriers/barriers affecting clinical practice (P < .001 and P = .001, respectively) and were more psychosocially oriented (P = .001). Conclusion Oncologists perceive many different barriers affecting psychosocial communication in clinical practice. Interventions aiming to improve psychosocial communication must therefore be multifaceted and individualized to clinics and individual oncologists. It is important to minimize barriers to facilitate optimal care and treatment of patients with cancer.
17
Sørlie, Mari-Anne, Terje Ogden, and Asgeir Røyrhus Olseth. "Preventing Problem Behavior in School through School-Wide Staff Empowerment: Intervention Outcomes." World Journal of Educational Research 2, no. 2 (October 8, 2015): 117. http://dx.doi.org/10.22158/wjer.v2n2p117.
Full textAbstract:
<p><em>The aim of this study was to examine the effects of the universal “Preventing Problem Behavior in School” (PPBS) intervention on both establishing high-quality learning environments and increasing the use of positive teaching strategies to prevent student problem behavior. PPBS was developed and piloted in Norway as an abbreviated version of the School-Wide Positive Behavior Support Model (SWPBS) and includes a four-day in-service training program for a school’s entire staff. Seventeen primary schools (Grades 1-7) implementing PPBS and 20 control schools engaging in “practice as usual” were compared using a three-wave measurement design. Multilevel analyses based on staff ratings indicated significant positive main effects of PPBS in the moderate range on the level of school behavior problems, positive behavior management, and perceived staff efficacy. Moreover, school size, implementation quality, proportion of unqualified staff members, and program training dosage moderated the intervention outcomes. Student ratings did not, however, support the staff ratings. The results are discussed in relation to the outcomes of the full-scale SWPBS model, meta-analyses of school-wide interventions, and measurement issues. Study limitations, strengths, practical implications, and future directions are highlighted.</em></p>
18
Schroeder, Ashley, Lori Pennington-Gray, and Laura Mandala. "Examining International Food Travelers' Engagement in Behaviors to Protect Themselves From Foodborne Illnesses While Abroad." Tourism Review International 22, no. 3 (December 14, 2018): 213–27. http://dx.doi.org/10.3727/154427218x15410074029643.
Full textAbstract:
In recent times, food travel has continued to gain in popularity and food and beverage activities are an important consideration for travelers. According to World Food Travel Association (WFTA), more than 9 in 10 travelers are now considered to be food travelers because they have participated in a "food or beverage experience other than dining out, at some point in the past 12 months." At the same time, travelers are an at-risk population for foodborne illnesses due to their tendency to eat out and experience local gastronomy. While health care providers and tourism service providers can and should advise travelers on ways to mitigate foodborne risks, it is ultimately the responsibility of travelers to protect themselves. Accordingly, the purpose of this study was to investigate antecedents of food travelers' engagement in personal protective behaviors (PPBs) related to foodborne illnesses during two phases of the travel experience: prior to and during travel. The independent variables were the extent of prior international travel experience, prior experience with foodborne illnesses, concerns about food safety, and food safety and foodborne illness risk perceptions. Data were collected via an online panel of food travelers from the US who had traveled outside of the country at least once in their lifetime (n = 758). Results revealed that concerns about food safety were antecedents of engagement in all five PPBs. Risk perceptions were antecedents of engagement in the during travel PPBs. The extent of prior international travel experience and prior experience with foodborne illnesses were inconsistent antecedents. The first two findings suggest that cognition (in terms of risk perceptions) is a driver of engagement in PPBs during travel and affect (in terms of concerns) is a driver of engagement in PPBs prior to and during travel. Theoretical and practical implications, as well as limitations and suggestions for future research are discussed.
19
Loganathan, Arun Kumar, Ravi Kishore Barla S S, and Jujju Jacob Kurian. "Unusual variant of pseudo prune belly syndrome." BMJ Case Reports 13, no. 10 (October 2020): e236611. http://dx.doi.org/10.1136/bcr-2020-236611.
Full textAbstract:
Unilateral pseudo prune belly syndrome (PPBS) is a rare variant with only two other cases found in the main literature until. We present a 9-month old boy with left-sided lax abdominal wall, undescended testes and major vesicoureteric reflux involving only the left side. He underwent left orchidopexy and left end ureterostomy followed by left nephrectomy. Unilateral variant supports the theory of mesodermal arrest as a cause for prune belly syndrome. Treatment is individualised and prognosis is relatively better when compared with other variants of PPBS.
20
Katsuta, J., and H. Shibaoka. "Inhibition by kinase inhibitors of the development and the disappearance of the preprophase band of microtubules in tobacco BY-2 cells." Journal of Cell Science 103, no. 2 (October 1, 1992): 397–405. http://dx.doi.org/10.1242/jcs.103.2.397.
Full textAbstract:
The effects of two kinase inhibitors, staurosporine and K-252a, on the development and the disappearance of the preprophase band of microtubules (PPB) were studied in tobacco BY-2 cells, the cell cycle of which had been synchronized. Treatment of cells at late G2 phase or at prophase with 20 micromolar staurosporine or 2 micromolar K- 252a for 2 or 3 h caused a decrease in the rate of development of PPBs and inhibited the disappearance of PPBs once they had developed, with the resultant accumulation of cells with a PPB. Cortical microtubules (MTs) or PPBs on protoplast ghosts, which were prepared from BY-2 cells in late G2 phase or at prophase, disappeared on treatment of the ghosts with ATP or ATP(gamma)S but not on treatment with AMP-PNP. The effect of ATP on the disappearance of MTs on the ghosts was suppressed by 20 micromolar staurosporine. Although 2 micromolar K-252a applied to the culture medium suppressed the anticipated disappearance of PPBs, it did not suppress the disappearance of MTs on the ghosts that was caused by ATP. We propose tentatively that a kinase sensitive to staurosporine but not to K-252a is directly involved in the disappearance of MTs and that a kinase that is sensitive to K-252a is indirectly involved in this process. The disappearance of MTs on protoplast ghost that was induced by ATP did not occur in the presence of 20 micromolar taxol.
21
Kadiyala, Sri Ramulu, Karthik Rao, Nr Rao, Ram Bhat, Jayaprakash Rao, Navin Patil, and Balaji O. "ASSOCIATION OF POSTPRANDIAL BLOOD SUGAR WITH HYPERCOAGULABILITY IN COMPARISON TO FASTING BLOOD SUGARS IN DIABETIC AND HEALTHY PATIENTS: A CROSS-SECTIONAL STUDY." Asian Journal of Pharmaceutical and Clinical Research 10, no. 7 (July 1, 2017): 378. http://dx.doi.org/10.22159/ajpcr.2017.v10i7.18806.
Full textAbstract:
Objective: The aim of this study was to find the association of postprandial blood glucose with hypercoagulability in comparison to fasting blood sugars(FBS) in diabetic and healthy patients.Methods: The present study involved a total of 156 patients, of which 78 were taken as cases (diabetics) and other 78 as controls (non-diabetics). Laboratory analysis included prothrombin time (PT), activated partial thromboplastin time (APTT), fibrinogen assay done along with fasting, and postprandial sugars.Results: Platelets in diabetics and healthy controls were in normal range. Decrease in PT and partial thromboplastin time was noted in diabetics compared to non-diabetic controls. Fibrinogen levels were increased in cases compared to controls. Changes in PT values were more significant with postprandial blood sugar (PPBS) levels when compared to FBS levels, and APTT follows the same pattern with more in PPBS levels and FBS levels in diabetics. PPBS showed elevated fibrinogen when compared to FBS in diabetics as well as non-diabetics.Conclusion: Type 2 diabetes mellitus is a hypercoagulable state as proven by the following results of our study.
22
Besnili, Zeynep Nur, and Ibrahim Tanrikulu. "Development and validation of the preschool peer bullying scale-teacher form." Journal of Psychologists and Counsellors in Schools 31, no. 1 (March 15, 2021): 46–62. http://dx.doi.org/10.1017/jgc.2021.1.
Full textAbstract:
AbstractBased on labelling theory, the Preschool Peer Bullying Scale-Teacher Form (PPBS-Teacher Form) was developed, and its validity and reliability were tested in this current study. There were 279 Turkish preschool teachers (96% females) in the preliminary study sample. Exploratory factor analyses were conducted with the data from the preliminary study sample, revealing 14 items with two factors, named as physical-relational bullying and verbal bullying. There were 247 Turkish preschool teachers (97% females) in the cross-validation study sample. Confirmatory factor analyses were carried out with the data from the cross-validation study sample, revealing adequate fit to the data. The internal consistency coefficients were high for the two study samples. Hence, the PPBS-Teacher Form is a valid and reliable measurement instrument to assess preschool peer bullying without labelling students as bullies or victims. The PPBS-Teacher Form aims to contribute to the extant research on early childhood bullying by attracting attention to the risks of labelling preschool students as bullies or victims. Practical implications are discussed for school counsellors and psychologists, parents and researchers.
23
Omolehinwa, Eddy. "PPBS in Nigeria: Its origin, progress and problems." Public Administration and Development 9, no. 4 (September 1989): 395–404. http://dx.doi.org/10.1002/pad.4230090406.
Full text
24
Cui, Bin, Feifei Wang, Linda Dong-Ling Wang, Chengyun Pan, Jun Ke, and Yi Tian. "A Comparative Analysis of Risk Perception and Coping Behaviors among Chinese Poultry Farmers Regarding Human and Poultry Infection with Avian Influenza." International Journal of Environmental Research and Public Health 16, no. 20 (October 11, 2019): 3832. http://dx.doi.org/10.3390/ijerph16203832.
Full textAbstract:
Poultry farmers face a dual risk when mutant avian influenza (AI) virus exhibits zoonotic characteristics. A/H5N1 and A/H7N9 are two principal strains of the AI virus that have captured public attention in recent years, as they have both been reported and can infect poultry and humans, respectively. Previous studies have focused either on poultry farmers’ risk perception and biosecurity preventive behaviors (BPBs) against A/H5N1 infection with poultry, or on their risk perception and personal protective behaviors (PPBs) against human infection with A/H7N9, even though these two strains often appear simultaneously. To bridge this research gap, a survey (N = 426) was conducted in the Chinese provinces of Jiangsu and Anhui to assess risk perception and coping behaviors adopted by poultry farmers facing the dual risk of these two viral strains. Paired sample t-tests revealed that farmers’ perceived risk of poultry infection with A/H5N1 was significantly higher than their perceived risk of human infection with A/H7N9, and that their reported frequency of BPBs against A/H5N1 was significantly higher than the frequency of PPBs against A/H7N9. Moreover, farmers were less familiar with AI infection in human beings compared to that in poultry, but they felt a higher sense of control regarding human AI infection. Multivariate regression analyses showed that farm size and perceived risks of both human and poultry infection with AI were positively associated with BPBs and PPBs. The findings of this research suggest that a campaign to spread knowledge about human AI infection among poultry farmers is needed, and that a policy incentive to encourage large-scale poultry farming could be effective in improving implementation of BPBs and PPBs.
25
Datey, Purnima, Alex Hankey, and H. R. Nagendra. "Combined Ayurveda and Yoga Practices for Newly Diagnosed Type 2 Diabetes Mellitus: A Controlled Trial." Complementary Medicine Research 25, no. 1 (September 29, 2017): 16–23. http://dx.doi.org/10.1159/000464441.
Full textAbstract:
Background: The increasing prevalence of type 2 diabetes in India is a cause for national concern, particularly the spiraling cost burden to the country. As one approach to stop its increase, Yoga medicine has been widely implemented, finding popularity with all social strata. Here, we report a study suggesting that treatment with fresh herbal juices and Yoga can improve the levels of blood glucose and hemoglobin A1c (HbA1c) in people with pre-diabetes. Methods: Study design: 3-arm controlled trial 3 months in duration. Participants: 157 male prisoners with newly diagnosed, high fasting blood sugar (FBS) and postprandial blood sugar (PPBS) levels. Group interventions: (1) Rasahara and Yoga, (2) Yoga, (3) no intervention. Assessments: FBS and PPBS levels were measured every 2 weeks; HbA1c and blood lipids were determined pre- and post-intervention. Results: Significant decreases occurred in the FBS (-21.13 ± 21.16 mg/dl) and PPBS levels (-15.02 ± 14.89 mg/dl) in group 1 (both p < 0.0001) and in the FBS level (20.62 ± 32.68 mg/dl) in group 2 (p = 0.0005), while the increases in group 3 attained significance only for the PPBS level (9.62 ± 21.83 mg/dl) (p = 0.0022). Observed changes in HbA1c were: group 1, -0.044 ± 0.059 mg/dl; group 2, +0.024 ± 0.456 mg/dl (not significant); and group 3, +0.365 ± 0.369 mg/dl (p < 0.0001). Conclusions: This study of Yoga for the treatment of diabetes shows that all male prisoners could benefit from the Yoga prison programs. Addition of Yoga programs to state and federal activities at all levels is now national policy in India. Follow-up studies should be carried out to obtain more robust results.
26
Kumar, Sandeep, Ajay Kumar, and Mohammad Mustufa Khan. "Estimation of Aldose Reductase Activity and Malondialdehyde Levels in Patients with Type 2 Diabetes Mellitus." Biomedical and Pharmacology Journal 12, no. 2 (June 26, 2019): 1001–7. http://dx.doi.org/10.13005/bpj/1728.
Full textAbstract:
Type 2 diabetes mellitus (T2DM) is a metabolic disorder characterized by hyperglycemia due to insufficient secretion or action of insulin.Elevated oxidative stress and diminished antioxidants may play an important role to develop T2DM and its complications. Aldose reductase (AR) enzyme plays a key role in the reduction of glucose to sorbitol by Polyol pathway. To estimate the AR activity and malondialdehyde (MDA) levels and in patients with T2DM. In this case-control study, a total number of 60 subjects (30 T2DM and 30 age-matched controls) wererecruited.Fasting blood sugar (FBS), Post-Prandial blood sugar (PPBS), AR activity and MDA levels were estimated in all the subjects. The AR activity was estimated by nicotinamide adenine dinucleotide phosphate hydrogen (NADPH) oxidation method. The plasma MDA levels were estimated by the thiobarbituric acid reactive substance (TBARS) method. For Statistical analysis, all the data were compared between the two groups by using unpaired t-test. Pearson correlation coefficient was calculated among T2DM. A P value <0.05 was considered as statistically significant for all data analyzed. The mean of FBS, PPBS, AR activity, and MDA levels were found significantly high in T2DM as compared to controls (P<0.001, P<0.001, P<0.001, P<0.001, respectively). A significant positive correlation was found between FBS and PPBS among T2DM (r=0.71, P<0.01). However, There was no significant correlation found between AR activity and MDA level among T2DM (r=0.002, P>0.05). Results showed thatthe mean of FBS, PPBS, AR activity, and MDA levels were found significantly higher in T2DM than controls. There was no significant correlation found between AR activity and MDA level among T2DM.
27
K. V., Harish, Hareesh R., and Akshatha Savith. "Study of serum adiponectin levels for early detection of type 2 diabetes mellitus and its complications on kidney." International Journal of Advances in Medicine 8, no. 2 (January 27, 2021): 171. http://dx.doi.org/10.18203/2349-3933.ijam20210102.
Full textAbstract:
Background: Type 2 diabetes mellitus is a chronic metabolic disorder due to insulin resistance caused by destruction of beta cells of pancreas. Insulin resistance in newly diagnosed type 2 diabetes mellitus patients leads to hyperglycemia. Serum adiponectin is a more sensitive and specific biomarker for early detection of diabetic nephropathy than urinary microalbuminuria.Methods: This is a case-control study conducted in Akash Institute of Medical Sciences, A total 180 subjects (120 cases and 60 controls). All the subjects included after informed consent, blood samples and urine samples are collected from the all the subjects. The serum Adiponectin and was estimated by using enzyme-linked immunoassay (ELISA) and fasting blood sugar (FBS), post prandial blood sugar (PPBS) and renal function test (RFT) was also estimated by laboratory standard methods.Results: This study was evaluated the FBS, PPBS, RFT and serum adiponectin levels in patients with type 2 diabetes mellitus patients and compare them with healthy controls. The serum adiponectin levels more significantly elevated in newly diagnosed type 2 diabetes mellitus patients and compared with the healthy controls. The study also found that significantly elevated levels of FBS, PPBS and RFT in type 2 diabetes mellitus patients and compared with the healthy controls, The statistically significant levels of serum adiponectin in patients with type 2 diabetes mellitus and when compared with the controls (p= 0.0001).Conclusions: The study suggesting that the s estimation of serum adiponectin levels in newly diagnosed type 2 diabetes mellitus patients useful for early detection of diabetic nephropathy. Because elevated levels of serum adiponectin in patients with newly diagnosed type 2 diabetes mellitus, this levels are positively correlated with the FBS and PPBS.
28
Rodrigues, Prudence Attilade, Anu Balan, and Charumathi Purushothaman. "A PROSPECTIVE COMPARATIVE OBSERVATIONAL STUDY ON SAFETY, EFFICACY AND COST EFFECTIVENESS OF INSULIN AND THEIR ANALOGUES." International Journal of Pharmacy and Pharmaceutical Sciences 10, no. 7 (July 1, 2018): 62. http://dx.doi.org/10.22159/ijpps.2018v10i7.21464.
Full textAbstract:
Objective: The objective of this study was to compare safety, efficacy and cost effectiveness of insulin and their analogues when compared with human insulin in patients with type-2 diabetes mellitus.Methods: A prospective observational study was carried out in a multispecialty hospital. The inpatients and outpatients from general medicine and endocrinology departments were included in our study for a period of 6 mo. The diabetic profile such as FBS, PPBS, HbA1c and body weight of the diabetic patients at the initial visit and follow up visit was documented.Results: This study showed a statistically significant reduction in HbA1c, PPBS, and FBS levels from the baseline in insulin analogue users. It was found that, insulin analogue with metformin showed statistical improvement (P<0.05) in FBS, PPBS, HbA1c as well as body weight and also found to be a cost-effective treatment according to Incremental cost-effectiveness ratio (ICER) decision matrix.Conclusion: This study concluded that type 2 diabetes patients underlined with the treatment using insulin analogue showed a better glycemic control when compared to human insulin. Metformin was the better OHA option in type-2 diabetes mellitus when compared with sulphonylureas and also metformin showed less weight gain than sulphonylureas.
29
R., Hareesh, Harish K. V., and Akshatha Savith. "Association of serum amylase and lipase levels in newly diagnosed type 2 diabetes mellitus." International Journal of Advances in Medicine 8, no. 2 (January 27, 2021): 254. http://dx.doi.org/10.18203/2349-3933.ijam20210101.
Full textAbstract:
Background: Type 2 diabetes mellitus is a chronic metabolic disorder due to insulin resistance caused by destruction of beta cells of pancreas. Insulin resistance in newly diagnosed type 2 diabetes mellitus patients leads to hyperglycemia. Serum amylase and lipase levels is an exocrine enzyme produced by acinar cells of pancreas. Altered levels of serum amylase and lipase leads to endocrine disorders, metabolic syndrome and diabetes mellitus.Methods: This is a case-control study conducted in Akash Institute of Medical Sciences, A total 100 subjects (50 cases and 50 controls). All the subjects included after informed consent, blood samples are collected from the all the subjects. The serum amylase and was estimated by using enzymatic commercial available kits and fasting blood sugar (FBS), post-parandial blood sugar (PPBS), renal function test (RFT) and liver function test (LFT) was also estimated by laboratory standard methods.Results: This study evaluated the FBS, PPBS, RFT, LFT, Amylase and Lipase levels in patients with newly diagnosed type 2 diabetes mellitus patients and compare them with healthy controls. The serum amylase and lipase levels more significantly elevated in newly diagnosed type 2 diabetes mellitus patients and compared with the healthy controls. The study also found that significantly elevated levels of FBS, PPBS, RFT and LFT in newly diagnosed type 2 diabetes mellitus patients and compared with the healthy controls, The statistically significant levels of serum amylase and lipase levels in patients with newly diagnosed type 2 diabetes mellitus when compared with the controls (p=0.0001).Conclusions: The study suggesting that to estimation of serum amylase and lipase levels in newly diagnosed type 2 diabetes mellitus patients useful for early detection of diabetes mellitus and its complications. Because elevated levels of serum amylase and lipase in patients with newly diagnosed type 2 diabetes mellitus, these levels are positively correlated with the FBS and PPBS.
30
V. Gadge, Pradeep, Roshani P. Gadge, and Nikita D. Paralkar. "Patients characteristics associated with better glycemic response to teneligliptin and metformin therapy in type 2 diabetes: a retrospective study." International Journal of Advances in Medicine 5, no. 2 (March 21, 2018): 424. http://dx.doi.org/10.18203/2349-3933.ijam20181082.
Full textAbstract:
Background: Teneligliptin was recently approved for type 2 diabetes (T2D) management in India and is used as monotherapy or in combination with different antidiabetic drugs. The aim of this study was to identify patients’ characteristics associated with better glycemic response to teneligliptin and metformin.Methods: A retrospective analysis of data was performed in patients of T2D with HbA1c above 7% who were treated with teneligliptin 20 mg/d as add on to metformin (500-100 mg/d) and whose follow-up data at 12-weeks was available. Fasting blood sugar (FBS) and post-prandial blood sugar (PPBS) changes were analysed. Results: Among 66 patients included in analysis, mean age was 61.0±9.8 years and 53% were females. Median duration of diabetes was 2 years. At 12-weeks, a significant reduction PPBS was observed (mean change: -14.3 mg/dL, p=0.009) but not in FBS (mean change: -2.4 mg/dL, p=0.353). Among different patients’ characteristics, age ≤60 years (p=0.006), duration of ≤1 year (p=0.023), body-mass index ≥25 kg/m2 (p=0.009), presence of dyslipidemia (p=0.05) and absence of complications (p=0.012) were associated with significant reduction in PPBS but not in FBS.Conclusions: A younger, newly-diagnosed, obese T2D patients with dyslipidemia without any complications of diabetes can derive better therapeutic effectiveness from teneligliptin added to metformin. These findings need to be confirmed in large, prospective, long duration study.
31
Pimenta, Filipa, Adriana Bernardino, Raquel Rosas, Ana Tapadinhas, and Isabel Leal. "Satisfação com o Suporte Social e Perda de Peso — Estudo Transversal." Psychology, Community & Health 5, no. 2 (August 8, 2016): 102–14. http://dx.doi.org/10.5964/pch.v5i2.173.
Full textAbstract:
ObjetivoPotencial moderador e mediador da eficácia nas intervenções para perda de peso bem-sucedida (PPBS), o suporte social é poucas vezes avaliado neste contexto. Pretende-se averiguar a relação entre a percentagem de peso perdido e variáveis sociodemográficas e psicológicas, incluindo satisfação com o suporte social, em pessoas que realizaram uma PPBS.MétodoNo total, 105 adultos com PPBS (ou seja, perda igual ou superior a 7% do peso inicial, com manutenção mínima de 12 meses) preencheram a Escala de Satisfação com o Suporte Social e um questionário para recolha de informação sociodemográfica, estado de saúde psicológica e estilos de vida.ResultadosO modelo estrutural com as dimensões de satisfação com a família e intimidade apresentou um bom ajustamento (χ2/gl = 1,343; CFI = 0,943; GFI = 0,924; RMSEA = 0,057, p < 0,001; C.I. 90% = ]0,000; 0,093[); a satisfação com o suporte familiar (β = 0,193;p= 0,081) e a existência de uma relação afetivo-sexual (β = -0,184; p = 0,082) foram as únicas variáveis a predizer marginalmente a percentagem de peso perdido.ConclusãoParticipantes mais satisfeitos com o suporte familiar (no mínimo, um ano após a PPBS) perderam uma maior percentagem de peso; assim, a satisfação com suporte social da família poderá ser uma variável relevante no processo de perda de peso. Todavia, a natureza do estudo (tipo de estudo e de amostra) torna necessária mais investigação na área para confirmar este resultado.
32
Kalyani Praba P, Thamarai Selvi K, Vijay Anand B, and Saravanan A. "Does Hydroxychloroquine Improve Glycemic Status and Lipid Profile in Rheumatoid Patients with Diabetes Mellitus – An Observational Study." International Journal of Research in Pharmaceutical Sciences 12, no. 1 (January 13, 2021): 423–29. http://dx.doi.org/10.26452/ijrps.v12i1.4144.
Full textAbstract:
Rheumatoid arthritis is an autoimmune disease, causing chronic inflammation of small joints in hands and feet. The chronic inflammation and corticosteroid use in rheumatoid patients predispose them to insulin resistance and diabetes. Hydroxychloroquine, a proven drug in rheumatoid arthritis, seems to be beneficial in diabetes and also reduces the risk of cardiovascular events. This study was done to find out the role of hydroxychloroquine on the glycemic status and lipid profile in Rheumatoid patients having treatment with Diabetes mellitus. 50 patients with both RA and DM in the middle age group were categorized into HCQ and Non-HCQ group. Both the groups were followed up for 6 months. Their glycemic status and lipid profile were compared by measuring FBS, PPBS, HbA1C, triglycerides, total cholesterol, VLDL, LDL and HDL. Statistical analysis was done by student t test. The mean FBS, PPBS, HbA1C values in HCQ Group patients decreased significantly from 155.16, 200.12 and 8.26 to 135.80, 174.60 and 7.49 respectively in the follow-up period. In the Non-HCQ group, there was no significant change in mean FBS and PPBS after 6 months. Mean HbA1C increased from 8.13 to 8.33 in Non-HCQ group. Triglycerides, total cholesterol, VLDL and LDL also were found to be reduced in patients who had taken HCQ. In Rheumatoid patients with diabetes, use of HCQ improves their glycemic status and reduces the lipid abnormalities.
33
Doros, Leslie Ann, Jiandong Yang, Amanda Field, Christopher Rossi, Gretchen M. Williams, Kris Ann Pinekenstein Schultz, Louis P. Dehner, Yoav H. Messinger, and D. Ashley Hill. "Pleuropulmonary blastoma: The causative role of germ-line DICER1 mutations." Journal of Clinical Oncology 31, no. 15_suppl (May 20, 2013): 10024. http://dx.doi.org/10.1200/jco.2013.31.15_suppl.10024.
Full textAbstract:
10024 Background: Pleuropulmonary blastoma (PPB) is a rare, aggressive childhood lung cancer that is often the first manifestation of the PPB-DICER1 familial tumor predisposition which includes other benign and malignant conditions. The initial genetic mutation is inherited by a germ-line loss of function of DICER1 gene which was discovered by Hill et al. It is proposed that loss of DICER1 expression alters miRNA regulation of key regulatory cellular mechanisms which promote tumor growth. PPB can progress from the purely cystic, curable Type I to a high-grade Type III having a dismal prognosis. We sought to determine the frequency of DICER1mutation in the largest cohort of PPB patients to date. Methods: We obtained germ-line DNA from saliva or blood samples from 113 PPB patients collected from 2005-2012. DNA was extracted using the Maxwell 16 Research System (Promega Corporation, Madison WI). Sample quality and quantity was checked using the Nanodrop 2000 (Thermo Scientific, Wilmington, DE). Sequencing was performed using the Sanger sequencer. For a subset of cases we used targeted sequencing services or full gene sequence analysis (Ambry Genetics, Aliso Viejo, CA). Results: Seventy-four (65.5%) PPB patients were found to have deleterious DICER1germ-line mutations. The most common mutation type found was small insertion/deletions. These 74 samples were composed of 7 (9.5%)Type Ir PPBs, 22 (29.7%)Type I PPBs, 24 (32.4%) Type II PPBs, and 21 (28.4%)Type III PPBs. The following Table shows a summary of mutation types identified. Conclusions: Our results confirm that DICER1 germline mutations are the most common genetic alterations in PPB making it critical for genetic testing to be performed at diagnosis. Additionally, this underscores the need for important correlative studies to describe the genotype-phenotype relationship in order for appropriate screening guidelines to be developed and implemented to allow for early detection. While a majority of cases are explained by germline DICER1 mutations using current sequencing methods, further investigation is warranted to elucidate other possible mechanisms in the development of PPB. [Table: see text]
34
Behera, Surendranath, and Siddharth Behera. "A clinical investigational study on safety and effective management of type-2 diabetes mellitus patients by using sitagliptin." International Journal of Advances in Medicine 6, no. 5 (September 23, 2019): 1672. http://dx.doi.org/10.18203/2349-3933.ijam20194241.
Full textAbstract:
Background: To study the health and efficiency of the more up to date oral hypoglycemic specialist sitagliptin in the executives of sort 2 diabetes mellitus patients. In our examination authors have enlisted 250 patients who met our investigation criteria of which authors ordered dependent on age and lab information, most of patients in the age bunch between 45-55 years (n=97, 39.2%), the RBS was diminished to Comparatively estimations of RBS, FBS, PPBS, HbA1C were decreased in follow up than benchmark esteem.Methods: This simultaneous observational investigation was done when all is said in done department of General Medicine of Hi-Tech Medical College and Hospital, Bhubaneswar, Odisha for a time of 6 months in which type 2 diabetes mellitus patients were enrolled dependent on incorporation and avoidance criteria and were pursued to assess the adequacy and security of sitagliptin. Information was dissected by utilizing chart cushion crystal understudy T-test.Results: Authors can presume that sitagliptin use was not related with any dangers and is compelling in the board of Type 2 diabetics, treatment with sitagliptin gave clinically significant decreases in HbA1C, RBS, FBS, PPBS by utilizing this investigation authors realize that gliptins are considerably more protected and powerful in the treatment of sort 2 diabetes mellitus.Conclusion: Treatment with sitagliptin provided clinically meaningful reductions in HbA1C, RBS, FBS, PPBS by using this study authors know that sitagliptins are much more safe and effective in the treatment of type 2 diabetes mellitus.
35
Dasegowda, Shashikala Magadi, Ashok Kumar Jeppu, Sushith, and Kavitha Ashok Kumar. "Relation of Serum Adenosine Deaminase to Some Risk Factors in Type 2 Diabetes Mellitus." Journal of Health Science Research 1, no. 1 (June 24, 2016): 13. http://dx.doi.org/10.18311/jhsr/2016/v1/i1/4726.
Full textAbstract:
<strong>Aim</strong>: Study was conducted to compare and correlate the levels of serum adenosine deaminase and serum uric acid with Fasting Plasmaglucose (FPG), Post Prandial Blood Sugar (PPBS) and glycated hemoglobin in type 2 diabetes mellitus. <strong>Materials and Method</strong>: Study group consisted of 60 diabetics and 50 age and sex matched healthy individuals. Blood sample was collected in fasting state and two hours after the food for estimation of serum Adenosine Deaminase (ADA), uric acid, parameters of lipid profile, fasting and postprandial glucose. <strong>Result</strong>: An increased level of serum ADA, FPG, PPBS, parameters of lipid profile and glycated haemoglobin in type 2 diabetes mellitus compared to controls. A statistically significant correlation was seen between serum ADA as well as serum uric acid with, Fasting Plasma Glucose (FPG), Post Prandial Blood Glucose (PPBS), glycated haemoglobin. Serum ADA had shown significant correlation with the Triglyceride (TG), Total Cholesterol (TC), Low Density Cholesterol (LDL cholesterol). A negative correlation was seen between serum ADA acid and High Density Lipoprotein cholesterol (HDL cholesterol). <strong>Conclusion</strong>: Adenosine deaminase and serum uric acid levels increased and positively correlated with parameters of lipid profile and glycemic control. This indicates that ADA and serum uric acid can serve as predictor of glycaemic index and help to monitor the long term effects of diabetes mellitus.
36
K., Kanmani, and Sudha Subramanian. "Perinatal outcome in relation to maternal glycaemic control in gestational diabetes mellitus." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 6, no. 10 (September 23, 2017): 4618. http://dx.doi.org/10.18203/2320-1770.ijrcog20174452.
Full textAbstract:
Background: Early diagnosis and treatment of gestational diabetes with adequate antenatal care are essential to reduce the adverse neonatal outcomes.Methods: All selected women were subjected to a detailed history taking comprising of age, parity, prepregnant body weight, medication history, family history, medical history, detailed obstetric history. Then they were subjected to clinical examination and routine laboratory investigations. Antenatal women were diagnosed with GDM, when 75gm GCT ≥140mg/dl based on DIPSI criteria. Fasting and postprandial blood sugars (2hours) were done and if FBS and PPBS were normal, the patient was labelled as GDM on meal plan. If fasting > 96 mg/dl and 2-hr postprandial blood sugar >121 mg/dl, Inj.insulin was started. Patients were managed according to the FBS and PPBS values throughout antenatal period and the perinatal outcomes were studied.Results: Among 150 patients, multiparous women constitute 65.3% and primi 34.7%. 60% of the patients were in age group of 26 to 30 years.59.3% of patients were in BMI of range 25 to 30.Family history of diabetes was present in 24.7% of the patients. Previous history of GDM was present in 27.3% of cases.98% of GDM were detected in 2nd trimester. The percentage of cases presented with macrosomia was 8.7%, RDS 3.3%, hypoglycaemia 6%, hyperbilirubinemia 3.3%, IUD 0.7%, perinatal injury 1.3%, NICU admission requiring ≥3 days of admission was 12%.Conclusions: There is association of elevated FBS and PPBS values with occurrence of adverse perinatal outcome.
37
Piñeiro-Vázquez, Angel, Jorge Rodolfo Canul Solis, Fernando Casanova Lugo, Alfonso Juventino Chay-Canul, Armin Javier Ayala-Burgos, Francisco Javier Solorio-Sánchez, Carlos Fernando Aguilar-Pérez, and Juan Carlos Ku-Vera. "Emisión de metano en ovinos alimentados con Pennisetum purpureum y árboles que contienen taninos condensados." Revista Mexicana de Ciencias Pecuarias 8, no. 2 (March 29, 2017): 111. http://dx.doi.org/10.22319/rmcp.v8i2.4401.
Full textAbstract:
El objetivo fue evaluar el efecto de los taninos condensados (TC) contenidos en el follaje de arbóreas tropicales, sobre el consumo de materia seca y orgánica (CMS, CMO), la digestibilidad de la materia seca (DMS) y emisiones de metano (CH4) en ovinos alimentados con una ración basal de pasto Pennisetum purpureum. Cuatro ovinos de pelo con un peso vivo promedio de 21.6±2.0 kg se sometieron a cuatro tratamientos en un diseño cuadro latino 4 x 4. Los tratamientos fueron P. purpureum (PP), P. purpureum + Havardia albicans (PPHA), P. purpureum + Bursera simaruba (PPBS), y P. purpureum + Acacia pennatula (PPAP); el follaje de las arbóreas se incluyó en 300 g/kg de MS de la ración. El consumo, la digestibilidad y la producción total de metano entérico se midieron por periodos de 23 h. La producción de metano se midió en cajas de respiración de circuito abierto. El consumo y digestibilidad de la MS y materia orgánica (MO) entre los tratamientos PP, PPHA, PPBS y PPAP no se afectaron por la inclusión de los follajes de arbóreas en la ración (P>0.05). Cuando la producción de CH4 se expresó en L/kg del CMS, CMO o consumo de fibra detergente neutro los resultados fueron similares entre tratamientos (PP, PPHA, PPBS y PPAP) (P>0.05). Se concluye que los TC contenidos en el follaje de Havardia albicans, Acacia pennatula y Bursera simaruba no afectaron las emisiones de CH4 al nivel de incorporación de 30 % de la MS; tampoco se observaron efectos en el CMS, CMO, DMS y concentración molar de ácidos grasos volátiles.
38
Sapkota, Lokendra Bahadur, and Sangita Thapa. "Correlation between glycemic parameters and lipid profile in type 2 diabetic patients attending tertiary care centre in central region of Nepal." Journal of Chitwan Medical College 7, no. 1 (May 24, 2017): 20–24. http://dx.doi.org/10.3126/jcmc.v7i1.17365.
Full textAbstract:
Background: Diabetes Mellitus (DM) is a chronic metabolic disease characterized by hyperglycemia with type 2 DM accounting for more than 90% of adult diabetes cases worldwide. Hyperglycemia in type 2 DM is strongly linked with dyslipidemia which in turn increases risk for development of cardiovascular diseases. This study aimed to determine the correlation between glycemic parameters (fasting blood sugar-FBS, postprandial blood sugar-PPBS and glycated hemoglobin-HbA1c) and serum lipid profile in type 2 diabetic patients.Methods: Altogether 160 type 2 diabetic patients (Male=80 and Female=80) aged between 30-70 years visiting Chitwan Medical College Teaching Hospital (CMCTH) for their routine medical check-up were included in this study. Data were collected using preformed set of questionnaires and biochemical data were obtained from the laboratory analysis of the patient’s blood samples. Statistical analysis was done with SPSS version 20.0.Results: Hyperglycemia was significant as evident by elevated FBS, PPBS and HbA1c. Also, the serum lipid profile was deranged with elevated TC, TG, LDL, VLDL and lowered HDL levels suggestive of dyslipidemia. There was a Direct and significant correlation of glycemic parameters (FBS, PPBS and HbA1c) with total cholesterol (TC), triglyceride (TG), low density lipoprotein cholesterol (LDL-C) and very low density lipoprotein cholesterol (VLDL-C) while the correlation with high density lipoprotein cholesterol (HDL-C) was just reverse.Conclusion: Chronic hyperglycemia in type 2 DM is associated with dyslipidemia which further exposes risk for the development of cardiovascular diseases. HbA1c, being the gold standard for the assessment of glycaemia is also the better predictor of dyslipidemia in type 2 diabetic patients.
39
Umamaheswari, A., K. Bhuvaneswari, and R. Senthilkumar. "To Compare the Anti-Inflammatory Effect of Oral Hypoglycemic Drugs in Type 2 Diabetes Mellitus." Biomedical and Pharmacology Journal 11, no. 3 (September 18, 2018): 1667–74. http://dx.doi.org/10.13005/bpj/1535.
Full textAbstract:
Insulin resistance and endothelial dysfunction which shares multiple signaling pathways like hyperinsulinemia, glucotoxicity and inflammation in type 2 Diabetes Mellitus (DM) leads to several micro and macrovascular complications. Studies have shown the anti-inflammatory effects of certain oral hypoglycemic agents which will be helpful in preventing the impact of diabetes related complications. The study aimed to compare the anti-inflammatory effects of Sitagliptin and Acarbose in combination with Metformin and Sulfonylurea in Type 2DM patients by using Anti-inflammatory markers Interleukin-6 (IL6), high sensitive C-reactive protein (hsCRP) and also to compare the clinical outcome between these two groups by using the parameters Fasting blood sugar (FBS), Post prandial blood sugar (PPBS), hemoglobin A1c (HbA1C), Plasma Insulin. In this open labeled prospective parallel group clinical study 30 type 2 diabetes patients on Metformin and Sulfonylurea combination, with HbA1c value ≥7.5 were recruited in tertiary care hospital and divided into two groups based on their HbA1C levels and were added on either Acarbose or Sitagliptin along with Metformin Sulfonylurea combinations and were followed for 3 months. Parameters like FBS, PPBS, HbA1c, Plasma Insulin hsCRP, IL-6were measured before and after the study. In the study the mean value of FBS, PPBS, HbA1c, Plasma Insulin, Insulin Resistance, hsCRP were reduced in both Sitagliptin and Acarbose group, which were similar to the results of previous studies except IL6 which got reduced in Sitagliptin group but increased in Acarbose group. The study had showed the synergism of Sitagliptin with Metform in Sulfonylurea combinationin reducing inflammation however; still long term studies are required to confirm their anti-inflammatory effects.
40
Mohammed, Riyaz, and Mohammed Azfar Ali. "Once daily versus twice daily Linagliptin effect on glycemic levels in type 2 diabetes mellitus- an observational study." International Journal of Research in Medical Sciences 5, no. 10 (September 28, 2017): 4403. http://dx.doi.org/10.18203/2320-6012.ijrms20174567.
Full textAbstract:
Background: DPP-4 is widely distributed in endothelial cells, pancreas, uterus, liver, salivary glands, lymph node, spleen, and thymus. DPP-4 regulates glucagon-like peptide (GLP)-1, and glucose-dependent insulin tropic peptide (GIP) which leads to glucose homeostasis via enhancing insulin secretion and suppression of glucagon, which results in control of post-prandial and fasting hyperglycemia.Methods: These 40 patients who were enrolled as per the inclusion criteria of receiving metformin dosage of 2 gram per day in established type 2 diabetes mellitus patients with no comorbidities. these patients were divided randomly into two groups comprising of 20 patients each, group A received linagliptin 5 mg per day in addition to metformin 1gm twice daily whereas group B received linagliptin 5 mg per day in a fixed dose (Linagliptin + metformin) of 2.5/1000 twice daily.Results: In the present observational study, the mean age in group A was 46.7±9.4 compared to 51.65±9.9 in group B, p >0.05, mean BMI in group A was 27.8±1.1 compared to 27.28±0.93 in group B p >0.05, Mean FBS in group A was 157.9±24.1 compared to 146.2±21.8 in group B p >0.05, Mean PPBS in group A was 245.8±32.7 compared to 246.2±39.3 in group B p >0.05 and Mean HbA1c in group A was 7.67±0.58 compared to 7.6±0.5 in group B p >0.05. Group A patients were initiated on once daily linagliptin, there was a significant reduction in FBS, PPBS and HbA1c at the end of 6 months p <0.001. Similarly, Group B patients who were initiated on twice daily linagliptin also showed a significant reduction in FBS, PPBS and HbA1c at the end of 6 months p <0.001.Conclusions: The addition of linagliptin to metformin treatment was effective and well tolerated in patients with type 2 diabetes. Linagliptin add-on to metformin during the early course of treatment helps in delaying the exhaustion of pancreatic islet function. Plasma concentrations of linagliptin decline in at least a biphasic manner with a long terminal half-life (>100 hours), related to the saturable binding of linagliptin to DPP-4. The prolonged elimination phase does not contribute to the accumulation of the drug. Addition of linagliptin to metformin has shown a significant reduction in FBS, PPBS and HbA1c.
41
Young, Thomas-Durell. "Is the US’s PPBS Applicable to European Post-Communist Defence Institutions?" RUSI Journal 161, no. 5 (September 2, 2016): 66–75. http://dx.doi.org/10.1080/03071847.2016.1253382.
Full text
42
Leung, Chi Hung. "Factor structure of PPBS with Chinese preschoolers from low-income families." Children and Youth Services Review 53 (June 2015): 157–65. http://dx.doi.org/10.1016/j.childyouth.2015.04.002.
Full text
43
Ahmed, Farhena, Mahmudul Hoque, ASM Towhidul Alam, Shaheda Ahmed, and Nayeema Tasnim. "HbA1C in Patients with Gestational Diabetes Mellitus." Chattagram Maa-O-Shishu Hospital Medical College Journal 12, no. 3 (October 28, 2013): 11–15. http://dx.doi.org/10.3329/cmoshmcj.v12i3.16689.
Full textAbstract:
Introduction: Approximately 7% of all pregnancies are complicated by Gestational Diabetes Mellitus.. The study was designed to determine the relationship between HbA1c & Gestational Diabetes Mellitus to reduce complications & monitoring treatment. Methods: The present cross-sectional comparative study was carried out in departments of Biochemistry and Obstetrics & Gynecology, Chittagong Medical College, Chittagong, Bangladesh. The data were collected by a structured questionnaire including age, socioeconomic condition, gravida, para, blood pressure, BMI, FBS, PPBS & Family H/O diabetes mellitus. Patients suffering from shortened red blood cell life span, sickle cell disease or any other condition that could result in premature red blood cell death and longer red blood cell life span, such as vitamin B12 or folate deficiency were excluded. Total 110 pregnant women were included in this study. Among them 70 were considered as case (whose FBS &PPBS according to ADA criteria of FPG value of ?5.3mmol/l and the WHO criteria of a 2-h PPPG value of ?7.8mmol/l) and 40 were considered as control (whose FBS <5.3mmol/L & PPBS <7.8mmol/L). HbA1c were measured in all sample. Results: Study showed that HbA1c( 6%) were more increased in GDM patients than that of the normal pregnancy( (6.95±1.38% Vs 5.05 ±0.27 %, p<0.001).Result showed that percentage of raised plasma HbA1c is more in GDM patients than that of the normal pregnancy (57.1%,P=<0.001).Pearson,s correlation coefficient (r) showed that there are positive correlation between Blood Glucose Level & HbA1c (Fasting Blood Glucose & HbA1c,r=0.869,p=<0.001 and Post Prandial Blood Sugar & HbA1c, r=0.507, p=<.0.001). Conclusion: Significantly raised level HbA1c in GDM help to formulate a management plan and thereby reduce the complications of this disease. Chattagram Maa-O-Shishu Hospital Medical College Journal Volume 12, Issue 3, September 2013: 11-15
44
Sinha, Ragni, Robin Maskey, Sunil Adhikari, and Deependra Prasad Sarraf. "Effects of Momordica charantia (Bittergourd) and Trigonella foenum-graecum (Fenugreek) Supplements in Type-2 Diabetics Taking Allopathic Drugs." Journal of Drug Delivery and Therapeutics 10, no. 6 (November 15, 2020): 110–19. http://dx.doi.org/10.22270/jddt.v10i6.4503.
Full textAbstract:
Background: Bittergourd fruit and Fenugreek seeds are the herbal supplements well known with glucose and lipid-lowering properties.
Objective: To assess the effects of Bittergourd and Fenugreek supplements in Type-2 diabetics taking allopathic drugs on blood sugar and lipid profile.
Methods: Open-label, 4-parallel-group, prospective interventional clinical trial was conducted on 48 Type-2 diabetics.They were divided in to four groupsof 12 each. Group Ireceived allopathic drugs alone, Group II, III and IV received supplementation of Bittergourd juice, Fenugreek seeds and Bittergourd juice+Fenugreek seeds together respectively. Fasting blood sugar (FBS), postprandial blood sugar (PPBS) and fasting lipid profile were measured on day 0,7, 15, 30 and 90. P-value was set at 0.05 level of significance. One-way ANOVA and post-hoc multiple comparison by Tukey was applied using SPSS version 21.
Results: Forty two participants completed the study with no adverse events. Supplementation with Bittergourd juice + Fenugreek on day 90 significantly (p-value=0.021) lowered FBS by 19% (p-value=0.021) and PPBS by 35% (p-value=0.001). Supplementation with Fenugreek and Bittergourd juice+Fenugreek both on day 90 significantly (p-value=0.000) lowered serum cholesterol by 16% and 14%, Serum triglyceride by 16% and 21% and LDL-cholesterol by 18% and 17%; however, only Fenugreek supplementation was significantly (p-value=0.015) able to increase HDL-cholesterol by 10%.
Conclusion: Effects of different herbal supplements in Type-2 diabetics for 90 days was observed. Bittergourd juice+Fenugreek seeds combination can lower FBS and PPBS. Both Fenugreek seeds and Bittergourd juice+Fenugreek seeds combination could lower serum cholesterol, Triglyceride and LDL-cholesterol. However, only Fenugreek seeds were capable of increasing serum HDL-cholesterol.
Keywords: Bittergourd; Fenugreek; Herbal-supplement; Type 2 diabetes mellitus
45
Chung, Thai-Hoa, Augusto Stancampiano, Kyriakos Sklias, Kristaq Gazeli, Franck André, Sébastien Dozias, Claire Douat, et al. "Cell Electropermeabilisation Enhancement by Non-Thermal-Plasma-Treated PBS." Cancers 12, no. 1 (January 16, 2020): 219. http://dx.doi.org/10.3390/cancers12010219.
Full textAbstract:
The effectiveness of electrochemotherapy (ECT) in local eradication of tumours in human and veterinary medicine has been proven. ECT consists of increasing the uptake of cytotoxic drugs by means of pulsed electric fields (PEFs) that transiently permeabilise the cell membrane. Still, this tumour treatment includes some drawbacks that are linked to the characteristics of the intense electric pulses (EPs) used. Meanwhile, the emerging field of cancer therapies that are based on the application of non-thermal plasmas (NTP) has recently garnered interest because of their potentialities as rich sources of reactive species. In this work, we investigated the potential capabilities of the combined application of indirect NTP treatment and microsecond PEFs (µsPEFs) to outperform in vitro cell electropermeabilisation, the basis of ECT. Thus, phosphate-buffered saline (PBS) was plasma-treated (pPBS) and used afterwards to explore the effects of its combination with µsPEFs. Analysis of two different cell lines (DC-3F Chinese hamster lung fibroblasts and malignant B16-F10 murine melanoma cells), by flow cytometry, revealed that this combination resulted in significant increases of the level of cell membrane electropermeabilisation, even at very low electric field amplitude. The B16-F10 cells were more sensitive to the combined treatment than DC-3F cells. Importantly, the percentage of permeabilised cells reached values similar to those of cells exposed to classical electroporation field amplitude (1100 V/cm) when the cells were treated with pPBS before and after being exposed only to very low PEF amplitude (600 V/cm). Although the level of permeabilisation of the cells that are treated by the pPBS and the PEFs at 600 V/cm is lower than the level reached after the exposure to µsPEFs alone at 1100 V/cm, the combined treatment opens the possibility to reduce the amplitude of the EPs used in ECT, potentially allowing for a novel ECT with reduced side-effects.
46
Alkire, Linda, Johannes Pohlmann, and Willy Barnett. "Triggers and motivators of privacy protection behavior on Facebook." Journal of Services Marketing 33, no. 1 (February 11, 2019): 57–72. http://dx.doi.org/10.1108/jsm-10-2018-0287.
Full textAbstract:
Purpose Internet user privacy risks have been a topical subject with respect to consumers, corporations and governments. In line with the recent privacy scandals linked to social media, the aim of this study is to explore users’ privacy protection behaviors (PPB) on Facebook through the actions they take to protect their privacy, their underlying motives and the values behind these protective actions. Moreover, this study aims to address an unintended consequence of Facebook usage. Despite Facebook’s positive and uplifting goal of connecting people, consumers are forced to resort to specific behaviors to protect their privacy and well-being. Design/methodology/approach This study adopts an exploratory research approach by using a well-established qualitative technique: structured laddering interviews. In total, 20 in-depth personal interviews were conducted with the Millennials. Findings Results show that the process of privacy protection is initiated by experiences, uncertainty and literacy, rather than threats, which leads to concerns that trigger PPBs. The most common PPBs include: “Reflection,” “Avoidance,” “Intervention,” “Restriction,” “Control,” and “Restraint.” The underlying motives for the adoption of these strategies include: “Success,” “Security,” “Social Recognition,” “A World of Peace,” “Exclusivity of Self,” “Being in Control,” “Meaning” and “True Friendship”. Originality/value The present research adopts a transdisciplinary framework to help fill the gap regarding the interplay of PPBs on Facebook, the triggers of those behaviors and their underlying motives. It contributes to the service literature and practice as it provides insights into a growing area of interest, whereas more social media channels are being created and more services are using social media strategies to engage and interact with their customers. Finally, it addresses the growing need to consider the impact of technological services, including internet and social media, on consumers’ and societies’ well-being.
47
Eleftheriou, E. P., and B. A. Palevitz. "The effect of cytochalasin D on preprophase band organization in root tip cells of Allium." Journal of Cell Science 103, no. 4 (December 1, 1992): 989–98. http://dx.doi.org/10.1242/jcs.103.4.989.
Full textAbstract:
The relationship between microfilaments (Mfs) and microtubules (Mts) in the organization of the preprophase band (PPB) was investigated in Allium root tip cells subjected to treatment with cytochalasin D (CD). Mts and Mfs were visualized by indirect immunofluorescence and various parameters such as PPB width were analyzed quantitatively. In control samples, the PPB first appears as a wide Mt band that progressively narrows to an average width of 4 micrometre in mid-prophase. Randomly oriented Mfs are present throughout the cytoplasm of most interphase control cells. Preprophase and prophase cells, however, contain cortical Mfs arranged parallel to the PPB. The Mfs initially occupy much of the cortex but in most cells they progressively become restricted to an area wider than the PPB. In the presence of CD, the PPB fails to narrow and remains at least two-fold wider than in control cells. PPB width expressed as a percentage of nuclear or cell length also increases compared to controls. Widening is concentration dependent, and the effect of 10 micromolar CD is near maximal only 15 min after application of the drug. This rapid response suggests that a rebroadening of already condensed PPBs takes place. After as little as 15 min in CD, Mfs are replaced by many small specks and rods. Dual localizations of both Mts and Mfs show that prophase cells contain broad PPBs without Mfs. The rapid disorganization of Mfs, by CD, therefore coincides with the rebroadening of PPBs. CD-treated cells in metaphase, anaphase and telophase contain larger actin aggregates at the poles, as previously reported. The results indicate that Mfs play an important role in the narrowing of the PPB, which in turn is essential for determination of the exact position of the plane of division. They also indicate that movement of intact Mts is important in PPB organization.
48
Keleş, Aylin, and Seher Sarikaya Karabudak. "THE PARENTING BEHAVIORS OF PARENTS WITH INFANTS IN NEONATAL INTENSIVE CARE UNITS AND THE EFFECT OF INVASIVE PROCEDURES COMPORTAMENTELE PARENTALE ALE PĂRINȚILOR CU SUGARI ÎN UNITĂȚILE DE TERAPIE INTENSIVĂ NEONATALĂ ȘI EFECTUL PROCEDURILOR INVAZIVE." Jurnal Medical Brasovean, no. 1 (August 10, 2020): 43–51. http://dx.doi.org/10.31926/jmb.2020.1.8.
Full textAbstract:
Obiectiv: Studiul își propune sădeterminecomportamenteleparentale ale părinților cu sugari în unitățile de terapie intensivă neonatală și efectul procedurilor invazive asupra comportamentelor parentale.Metode: Acest studiuanalitic, în secțiune transversală, a fost realizat cu 250 de părinți ai căror copii au fost internați în unitatea de terapie intensivă neonatală. Datele au fost colectate folosind un formular informativ introductiv și Scala de comportament parental postpartum (PPBS). Datele au fost evaluate folosind statistici descriptive, testul Mann-Whitney U și testul Kruskal-Wallis.Rezultate: Scorul mediu al PPBS al mamelor a fost 3,76 ± 1,86, iar tații au fost 2,98 ± 1,79. Comportamentul parental al mamelor este afectat pozitiv de familie și negativde greutatea, lungimea și circumferința capului nou-născutului. A avea un copil cu acces vascular pentruproceduri invazive afecteazăîn mod pozitiv comportamentul parental al ambilor părinți, în timp ce un copil cu un cateter venei ombilicale sau un tub endotraheal îiafecteazănegativ.Concluzii: Comportamentulparental este modificat moderat pentru ambii părinți, iar mamele au avut un comportament parental mai pozitiv decât tații. A avea un copil cu acces vascular a afectat pozitiv comportamentul parental, dar faptul că un bebeluș cu un cateter venei ombilicale sau un tub endotraheal i-a afectat negativ.
49
Fang, Shuang, Zhusheng Shi, Qian Bai, Jia Ying Jiang, Shu Yun Wang, and Jian Guo Lin. "An Investigation of Direct Powder Forging of Nickel Superalloy FGH96." Key Engineering Materials 716 (October 2016): 793–99. http://dx.doi.org/10.4028/www.scientific.net/kem.716.793.
Full textAbstract:
Powder metallurgy (PM) nickel-based superalloy has been widely used in high temperature applications and is most commonly manufactured using hot isostatic pressing (HIP). However, HIP is an expensive process and takes a long time at high temperature which leads to the formation of networks of prior particle boundaries (PPBs). In this study, a recently developed processing method - direct powder forging (DPF) was employed to produce a PM nickel-based superalloy component, using a single acting hydraulic press under normal atmosphere. EBSD study has been conducted for its microstructure, grains size distribution, and grain boundary misorientation; and mechanical testing has been carried out for its hardness and tensile properties at room temperature and 650°C. It has been found that the DPFed material has reached full density in the whole component. Networks of PPBs have been broken in the direct powder forged FGH96 alloy. Compared with HIPed FGH96 alloy, the DPFed material has a substantially higher recystallisation nucleation degree and more recrystallised sub-grains. After heat treatment, the tensile properties of the direct powder forged FGH96 alloy match or surpass those of the material produced by HIP plus isothermal forging.
50
MINEYUKI, YOSHINOBU, TAKASHI MURATA, and MASAMITSU WADA. "Experimental Obliteration of the Preprophase Band Alters the Site of Cell Division, Cell Plate Orientation and Phragmoplast Expansion in Adiantum Protonemata." Journal of Cell Science 100, no. 3 (November 1, 1991): 551–57. http://dx.doi.org/10.1242/jcs.100.3.551.
Full textAbstract:
Division sites in higher plant cells are known to be determined before mitosis, and cell plates are precisely inserted into the predetermined division sites at the end of cytokinesis by unknown mechanisms. When apically growing protonemal cells of the fern, Adiantum capillus-veneris L., grown under red light are transferred to the dark, apical growth ceases and the protonemal cells then divide. However, this mitotic event can be influenced by subsequent exposure to light. If red-light pre-cultured protonemata are incubated in the dark and then transferred back to red light (after 28–36 h), apical growth resumes and the nuclei migrate toward the growing tips; interestingly, mitosis still occurs, although in an altered fashion. In the re-irradiated cells, timing of the premitotic nuclear positioning is delayed markedly and irregularly oriented cell plates are frequently observed. Re-irradiation with red light also causes an increase in cells without preprophase bands (PPBs) at prophase and the irregular expansion of the phragmoplast at late telophase, while early phragmoplast microtubule (MT) organization takes place normally. These data suggest the indirect involvement of PPBs in the guidance of phragmoplast expansion.