Dissertations / Theses on the topic 'Postprandial blood glucose'
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Amaral, Catarina Medeiros. "Effect of the ingestion of a mousse with cinnamon C. Burmannii on the postprandial blood glucose response of healthy subjects and its antioxidant power." Master's thesis, Instituto Superior de Ciências da Saúde Egas Moniz, 2013. http://hdl.handle.net/10400.26/5109.
Full textBackground: Cinnamon has been shown to reduce postprandial glycaemia and enhance insulin sensitivity in healthy adults.
Aims: To study the effect of C. burmannii on the postprandial blood glucose response of healthy subjects and its antioxidant capacity in a semi-solid food.
Design: Twenty four apparently healthy subjects participated in this study. They were randomly assigned in group A (reference meal) or group B (test meal). The blood glucose concentrations were measured before the ingestion of the meals and 30, 60, 90 and 120 minutes after the start of the meal. The test meal used consisted of 100 g of mousse mixed with 3 g of cinnamon.
Results: The addition of 3 g of cinnamon to the mousse had no significant effect in blood glucose response in terms of the areas under the curve (AUC) and in the different postprandial times (p>0,05). The mean Cmax was significantly lower after the ingestion of the reference meal than after the ingestion of the mousse with 3 g of C.burmannii (96 mg/dl VS 104,42 mg/dl; p=0,011). The chemical analysis showed that the mousse with 3 g of cinnamon has a much higher phenolic content and antioxidant capacity than the mousse without cinnamon.
Conclusions: The inclusion of cinnamon in the mousse increased the antioxidant capacity of this semi-solid food, however it did not reduce the postprandial glucose response in healthy subjects.
Wong, Evelyn Yin-Yue. "Effect of viscosity modification by fiber dose and heat treatment on postprandial blood glucose response." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp01/MQ28882.pdf.
Full textPannoni, Nina. "The Effect of Various Carbohydrate Supplements on Postprandial Blood Glucose Response in Female Soccer Players." Scholar Commons, 2011. http://scholarcommons.usf.edu/etd/3281.
Full textMohammed, Nadia H. J. "Effect of carbohydrate source on postprandial blood glucose in subjects with type 1 diabetes using insulin lispro." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2001. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp05/MQ63166.pdf.
Full textClaudia, Cecilia Yamamoto Noguchi. "Mathematical Model of Glucose-Insulin Metabolism Considering Meal Absorption Rate and Model-based Blood Glucose Control for Prandial State in Type 1 Diabetes." 京都大学 (Kyoto University), 2016. http://hdl.handle.net/2433/217171.
Full textHsieh, Tsung-han. "PANCREATIC EXPRESSION OF TRPA1, ITS ROLE IN INSULIN SECRETION AND ITS POSSIBLE EFFECT ON POSTPRANDIAL BLOOD GLUCOSE LEVELS." OpenSIUC, 2013. https://opensiuc.lib.siu.edu/theses/1331.
Full textBeneyto, Tantiña Aleix. "Robust and fault-tolerant strategies for controlling blood glucose in patients with type 1 diabetes." Doctoral thesis, Universitat de Girona, 2020. http://hdl.handle.net/10803/670998.
Full textLa T1D és una greu que requereix de monitorització i que ha de ser controlada de forma artificial subministrant insulina exògena. El pàncrees artificial (AP) és un sistema de llaç tancat resultant d'integrar una bomba d'insulina amb un CGM, i utilitza un sistema de control per automatitzar la infusió d'insulina. En aquest treball es presenten un nou sistema d’ajust i un sistema de control de vàries variables per a sistemes AP, dissenyat per ser robust davant la variabilitat del pacient, a menjars i exercici. Per augmentar la seguretat del pacient, també es dissenyen estratègies de detecció de fallades com una part integral dels sistema. Les estratègies proposades en aquest treball han estat validades extensivament en simulació i durant un assaig clínic, amb resultats prometedors
García, Jaramillo Maira Alejandra. "Prediction of postprandial blood glucose under intra-patient variability and uncertainty and its use in the design of insulin dosing strategies for type 1 diabetic patients." Doctoral thesis, Universitat de Girona, 2011. http://hdl.handle.net/10803/52564.
Full textEn esta tesis se propone un nuevo método para estimar la dosis y el instante de inyección que genere el menor riesgo para una terapia intensiva de insulina. El sistema de dosificación utiliza un algoritmo de optimización para determinar la dosis de insulina y el instante de inyección que reduzcan al máximo el riesgo de hiperglucemia e hipoglucemia posprandial en pacientes diabéticos tipo 1. Para ello, el algoritmo aplica una metodología que cuantifica el riesgo de sufrir diferentes grados de hipoglucemia e hiperglucemia en estado postprandial inducida por la terapia de insulina de acuerdo a los parámetros de cada paciente. Aplicando análisis intervalar modal se predice el nivel de glucosa postprandial considerando la variabilidad intrapaciente y otras fuentes de incertidumbre. Con un planteamiento del peor caso se calcula una predicción más segura de posibles episodios de hiperglucemia e hipoglucemia inducida por la terapia de insulina en términos de dichas incertidumbres.
Oviedo, Castillo Silvia. "Forecasting and decision support for type 1 diabetes insulin therapy using machine learning." Doctoral thesis, Universitat de Girona, 2019. http://hdl.handle.net/10803/667332.
Full textLa teràpia amb insulina per a pacients amb T1D tenen vàries ramificacions amb diferents graus d’automatització. Els avenços en sensors i dispositius de monitorització comporten un increment en la disponibilitat de dades. A més a més, l’ús d’algoritmes d’aprenentatge automàtic s’han popularitzat, facilitant així el desenvolupament de models per pronosticar Glucosa en Sang (GS) amb major facilitat. No obstant això, preveure els nivells de GS és una tasca complexa per a finestres de predicció més enllà de 30 minuts, i més encara, amb dades errònies o absents, la qual cosa és una limitació molt freqüent en aquest camp. Aquesta tesis està dedicada a la generació de models basats en aprenentatge automàtic per predir ja siguin nivells de GS utilitzant algoritmes de regressió o hipoglucèmia postprandial utilitzant algoritmes de classificació. L’aplicació d’aquests models van des de la teràpia de múltiples injeccions diàries (MID), fins a la teràpia SAP
"Matcha Tea and its Acute Effects on Postprandial Blood Glucose." Master's thesis, 2018. http://hdl.handle.net/2286/R.I.49415.
Full textDissertation/Thesis
Masters Thesis Nutrition 2018
"Developing the Optimal Vinaigrette Dressing for Managing Blood Glucose Concentrations." Master's thesis, 2017. http://hdl.handle.net/2286/R.I.43910.
Full textDissertation/Thesis
Masters Thesis Nutrition 2017
"Effect of Curcuma Longa (Turmeric) on Postprandial Glycemia in Healthy, Non-diabetic Adults." Master's thesis, 2017. http://hdl.handle.net/2286/R.I.44237.
Full textDissertation/Thesis
Masters Thesis Nutrition 2017
Magistrelli, Ashley M. "Effects of ground cinnamon on postprandial blood glucose levels between obese and normal weight individuals." 2010. http://liblink.bsu.edu/uhtbin/catkey/1607094.
Full textDepartment of Family and Consumer Sciences
Chung, Chun-Chuan, and 鍾君釧. "Applying Data Mining Technology to Explore the Effectiveness of Postprandial Blood Glucose Control in Diabetic Patients." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/jz5xen.
Full text國立屏東科技大學
資訊管理系所
106
Abstract Student ID:N10556004 Title of thesis:Applying Data Mining Technology to Explore the Effectiveness of Postprandial Blood Glucose Control in Diabetic Patients Total page:74 Name of Institute:Department of Management Information System, National Pingtung University of Science and Technology Date of Graduate:June, 2018 Degree Conferred:Master Name of Student:Chun-Chuan Chung Advisor:Deng-Neng Chen The Contents of Abstract in This Thesis: The population of diabetes is in an increasing trend nowadays. The Ministry of Health and Welfare has announced that the diabetes is ranked fifth of ten leading causes of death from 2017. Diabetes is a chronic metabolic syndrome disease, and it can get more easily to cause severe disease. Diabetes will damage health and waste more medical resources by long term.With the development of information technology and data science, data mining techniques have been extensively applied in all kinds of fields. This study has analyzed the medical examination database of a Regional Hospital in Southern Taiwan and applied C4.5 decision tree classifier in WEKA 3.8.1 to identify 6 key factors and extract 9 rules for the effectiveness of postprandial blood glucose control in diabetic patients. This research has revealed that the diabetic patients not receiving health education with different treatments will affect the postprandial blood glucose control. In order to enhance the credibility of the analysis results, we collected relevant medical literature and conducting an in-depth interview with a clinical medical expert for evaluation of the analysis results. The conclusions show that every result is similar to clinical experience. The contribution of this study is to apply data mining techniques to explore information that provide references and application for healthcare personnel. With the developed model of this study, doctors can provide better healthcare and treatment to diabetic patients by rules, and lower the huge medical burden. Keywords: data mining, Diabetes, Decision Tree algorithm
Chang, Jessica Lee Sing. "Gastric motor function in health and diabetes: implications for incretin hormone release and postprandial blood glucose regulation." Thesis, 2012. http://hdl.handle.net/2440/76101.
Full textThesis (M.Phil.) -- University of Adelaide, School of Medicine, 2012
"iDECIDE: An Evidence-based Decision Support System for Improving Postprandial Blood Glucose by Accounting for Patient’s Preferences." Doctoral diss., 2017. http://hdl.handle.net/2286/R.I.45517.
Full textDissertation/Thesis
Doctoral Dissertation Biomedical Informatics 2017
Yang, Chiao-Hsin, and 楊蕎芯. "A study of postprandial blood glucose and glycemic index measurement after having different conditions of cooked white rice." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/4n96ut.
Full text國立屏東科技大學
食品科學系所
105
Rice, the foremost food crop, is a staple food for people around the world. Moreover, rice varieties, processing, cookeries and physicochemical properties presents various GI (Glycemic Index) values. Most rice varieties are classified as high-GI foods. According to researches, people who have high-GI diets may increase risk of obesity, type 2 diabetes, diabetic complications, cardiovascular disease and some cancers. Low-GI diets, however improve insulin sensitivity and blood lipid and blood glucose level. Therefore, it is important to pay close attention to postprandial blood glucose and GI value of food. In order to study GI value of food, we investigated different methods of measuring GI values and physicochemical properties of foods in this study: (1) evaluating accuracy of GI by three different blood sampling methods; (2) measuring glycemic response and GI with gluten protein, dextrin fiber or canola oil added in cooked rice; (3) comparing effects of different cookeries, storage temperatures and storage durations on GI of cooked rice. First, we compared three different blood sampling methods (based on capillary whole blood, capillary plasma and venous plasma, respectively) of glycemic response, IAUC (incremental area under the blood glucose response curve) and GI for steamed rice, rice porridge and rice that stored overnight. The results showed that rice porridge produced the highest mean GI and mean IAUC (99.3 ± 0.6 and 4008.6 ± 390, respectively), followed by steamed rice (92.1 ± 0.4 and 3710 ± 363, respectively), and then that stored overnight rice (90.7 ± 0.4 and 3677 ± 366, respectively). In terms of blood sampling method, venous plasma show higher precision and lower coefficient of variation (CV) of GI, IAUC and glycemic response than other sampling method. Secondly, rice mixed with gluten protein, dextrin fiber or canola oil was tested for GI values. Venous plasma blood sample was taken to observe glycemic effect of rice according to first investigation. In this study, we determined the dose-response and mixture interaction effects of gluten protein, canola oil, and dextrin fiber combined with a portion of white rice on glycemic response and GI. The results showed that white rice has a GI value of 93.8±2.8. Supplementation with various amounts of canola oil and dextrin fiber reduced the GI slightly, whereas gluten protein significantly (p < 0.05) reduced the GI from 93.8 to 84.9 and 83.1, respectively. Analysis of the interaction of gluten, lipids, and dextrin on GI by using three-way ANOVA revealed that significant effects on GI value were found with gluten (p < 0.01) and dextrin (p < 0.05). Moreover, adding a gluten protein and dextrin fiber mixture yielded a larger glycemic control effect than adding a lipid and dextrin fiber mixture did. In conclusion, Food processing supplements gluten protein with rice products may associated with a reduction in overall postprandial glycemic response and induced a lower GI in healthy people. Finally studying, we examined the glycemic response of white rice to determine the effects of storage temperature (-20°C, 0°C, and 4°C) and storage duration (1, 3, and 5 days). Results were compared with cooked white rice (control, 25°C). Measurements were performed on Days 1, 3, and 5 to test the glycemic index (GI), incremental area under curve (IAUC), and blood glucose response. The results showed that the mean GI was highest for the control (93.5 ± 3.6), followed by those for the -20°C (87.4 ± 3.1), 4°C (84.1 ± 2.8), and 0°C (84.1 ± 2.7) test foods (Day 1). The GI values differed significantly with the storage duration (p < 0.05). In conclusion, white rice stored at 0°C for 5 days has the lowest glycemic response. Moreover, control group (25°C) exhibited the highest GI. In recent years, food choice and eating habits have changed dramatically. Our findings may serve as a reference for developing fast-food or low-GI emerge and conform to nutrition and health concepts applied to production of rice products.
Hsu, Yen-Ping, and 許燕萍. "Inhibitory effect of Psidium guajava L. and Morus alba L. leaves extracts on alpha-glucosidase activity and postprandial blood glucose." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/16236693602712548024.
Full text國立屏東科技大學
食品科學系所
98
Diabetes is one of leading causes of death, according to the statistics by Department of Health , Executive Yuan of Taiwan. In modern medicine, diabetes could be controlled by various medication. However, drugs always have undesirable side effects. Therefore, it becomes the goal to find the plant content which can decrease glucose concentration of the blood, reduce the incidence of complication, and prevent the side effects. Alpha-Glucosidase inhibitors (AGIs) are the effective glucose-lowering medicines, and is a key enzyme of carbohydrates digestion. Inhibition of α-glucosidase leads to a delayed and reduced rise in post-prandial blood glucose levels. The purpose of this study is to evaluate inhibitory effect of mixture extracts of P. guajava L. and M. alba L. leaves on α-glucosidase activity and postprandial hyperglycemia in normal and diabetic rats. The inhibition of α-glucosidase activity was assayed in vitro. The IC50 values of Psidium guajava L. and Morus alba L. were 2.25 mg/mL and 0.1 mg/mL, espectively. The IC50 value of commercial anti-hyperglycemic agent (Glucobay) was 6.41 mg/mL. The IC50 value of mixture extracts of P. guajava L. and M. alba L. was 0.07 mg/mL. In cytotoxicity test, murine embryonic liver cell line (BNL CL.2) which were treated with various concentration and various time of mixture extracts, the survival percentages and the shape were no significant effect. In vivo, after feeding 8 weeks with mixture extracts, the results of oral sucrose challenge test showed that the extracts can reduce sucrose hydrolysis to monosaccharide, and delay the absorption of glucose, leading to the suppression of meal-induced increase of glucose. The mixture of plants can decrease in triglyceride, glutamic-oxalocetic transaminase(GOT), glutamic- pyruvic transaminase(GPT) concentration in plasma, and increase HDL concentration. In histopathology assay, the DCL, DCM, DCH, DCG of diabetic-induced groups were observed slight pathology less than diabetic control(DC) group.
Kuo, Yu-Chen, and 郭育辰. "Strictinin isolated from Raw Pu-erh tea, a potent aphla-glucosidase inhibitor, reduces postprandial blood glucose in C57BL/6J mice." Thesis, 2019. http://ndltd.ncl.edu.tw/cgi-bin/gs32/gsweb.cgi/login?o=dnclcdr&s=id=%22107NCHU5111024%22.&searchmode=basic.
Full text國立中興大學
生物科技學研究所
107
Pu-erh tea, famous for its special aroma produced by particular processes. Pu-erh tea has been shown to ameliorate hyperglycemia by inhibit -glucosidase pathway, thus considered a healthy drink. In addition, hyperglycemia is major symptom in diabetes mellitus, and stabilized postprandial blood glucose (PBG) is one of strategies to cure and prevent diabetes. Clinical drug, acarbose, has the gastrointestinal adverse effects, such as flatulence, diarrhea, abdominal discomfort, impair patient compliance and limit clinical utility. Thus, finding a less side effects drug is highly anticipated. In experiment, Pu-erh tea infusions were determined to inhibit -glucosidase activity, and raw Pu-erh tea inhibited about 90% activity in 25 g/mL. Though the HPLC analysis, raw Pu-erh tea is rich in strictinin, ((-)-epigallocatechin gallate, EGCG). In vitro, the IC50 values of strictinin and EGCG against -glucosidase were 2.4 g/mL and 4.3 g/mL. In addition, we discover that the inhibition type of strictinin on -glucosidase is mixed type. In vivo, strictinin improve oral sucrose tolerance in C57BL/6J mice at dose 100 mg/kg, but didn’t improve oral glucose tolerance. The results indicated that strictinin decreased the PBG level by though inhibit -glucosidase path-way. Therefore, strictinin may have the potential to prevent diabetes.
Watson, Linda Ernestine. "A novel nutritional approach to the management of type 2 diabetes: effects of nutritional preloads on postprandial blood glucose and gastric emptying in type 2 diabetes mellitus." Thesis, 2018. http://hdl.handle.net/2440/115410.
Full textThesis (Ph.D.) (Research by Publication) -- University of Adelaide, Adelaide Medical School, 2018
Thota, Rohith N. "Curcumin and long-chain omega-3 polyunsaturated fatty acids: effects on glycaemic control and blood lipids." Thesis, 2018. http://hdl.handle.net/1959.13/1389618.
Full textType 2 diabetes (T2D) is the most common chronic metabolic disorder resulting from either deficit of insulin secretion and/or action. The transition of normal glucose tolerance to T2D is usually accompanied by a cluster of metabolic risk factors such as low-grade inflammation, oxidative stress, insulin resistance (IR) and dyslipidaemia. IR is one of the marked independent predictors among these cluster of metabolic abnormalities that mediates the transition in high risk states such as obesity, impaired glucose tolerance (IGT) and impaired fasting glucose (IFG) to overt T2D. IR also is often associated with decreased clearance of lipids and lipoprotein abnormalities, together representing a greater risk of cardiovascular disease (CVD) in both high risk and individuals with T2D. Several studies have employed lipid ratios, homeostatic models, and anthropometric measures as surrogate markers for predicting IR. However, none of these accounted for both insulin and lipid availability in a single model to predict IR or metabolic syndrome (MetS). Therefore, the first aim of my PhD project, presented in the chapter 3, was to develop a novel marker for IR and MetS that accounts for both insulin and lipid availability in a single model. We proposed and evaluated a novel physiologically relevant marker, InsuTAG (product of fasting insulin and fasting triglycerides) as a predictor of IR and MetS. Cross-sectional analysis of data from the Retirement Health and Life-style Study (RHLS, n=618) showed that InsuTAG is a strong predictor of IR over existing lipid based surrogate markers and anthropometric measures. Receiver operating curve analysis indicated InsuTAG (93%) as the favourable marker for IR over other lipid based surrogate markers and anthropometry measures. Prevalence of MetS was significantly higher in individuals with InsuTAG values above the optimal cut-off value of 11.2. InsuTAG exhibited a greater area under than curve than HOMA-IR for identifying MetS. Together these observations indicate the potential of InsuTAG for predicting IR and MetS. Despite effective lifestyle and pharmacological interventions, the prevalence of T2D is growing at an alarming rate in Australia, in line with global prevalence. Failure of long term compliance to these interventions is a major barrier for their effectiveness in halting the transition to T2D in high risk state individuals, indicating a necessity for alternative effective approach. Given the fact that pathogenesis of T2D is chronic, complex and often involving multiple pathological pathways, use of well tolerated dietary bio-active compounds appears to be a potential strategy for delaying the onset of T2D. Several pre-clinical and in-vitro studies have reported the ability of dietary bio-actives to down regulate multiple pathological mechanisms (chronic low-grade inflammation, IR, oxidative stress and β-cell dysfunction) that are involved in the pathogenesis of T2D. We hypothesised that a combination of two lipid-lowering and anti-inflammatory dietary bio-active compounds, curcumin and long-chain omega-3 polyunsaturated fatty acids (LCn-3PUFA), could potentially act in multiple pathways to improve the glycaemic control in individuals at high risk of developing T2D. My second aim, presented in chapter 4, was to evaluate the acute effects of curcumin and/or LCn-3PUFA on glycaemic responses. Therefore, in a randomised, cross over trial we investigated the postprandial glucose and insulin response to a single dose of curcumin and/or LCn-3PUFA in healthy individuals. The glucose levels were reduced by curcumin at as early as 30 min, and the maximum effect was observed at 60 min post meal consumption. Curcumin was found to be effective for lowering the insulin demand to control postprandial glucose levels. Similar results were observed following dietary supplementation with curcumin plus LCn-3PUFA. It was apparent that the postprandial effects on glycaemic control were primarily due to curcumin even in the combined treatment group. Thus, providing basis for long-term supplementation study with curcumin for glycaemic control. In chapter 5, a detailed study protocol for 2x2 factorial placebo controlled, double blinded randomised trial with long term (12 weeks) curcumin and LCn-3PUFA supplementation (COP-D trial) was presented. In chapter 6, we examined the effects of curcumin with or without LCn-3PUFA on glycaemic control and blood lipid levels in people at high risk of T2D. 12 weeks of supplementation with curcumin has effectively reduced the fasting insulin levels and IR in individuals with high risk of T2D. Parallel to these results, both curcumin and LCn-3PUFA were able to reduce the fasting triglycerides and atherogenic index of plasma, however the magnitude of reduction was greater with LCn-3PUFA supplementation. InsuTAG levels were also reduced with curcumin and LCn-3PUFA supplementation. However, this study failed to show any complimentary effects with concurrent administration of curcumin and LCn-3PUFA. Though IR and fasting triglycerides, were effectively reduced by these two bio-actives, we did not find any beneficial effects of curcumin and LCn-3PUFA supplementation on fasting glucose and glycosylated haemoglobin levels. In chapter 7, we designed a study to target commonly prevalent dyslipidaemia with curcumin and/or LCn-3PUFA in individuals with T2D (CALFOR-CVD trial). Participants were randomised to either placebo or curcumin or LCn-3PUFA, or curcumin plus LCn-3PUFA for six weeks. This pilot study has demonstrated that supplementation of curcumin can effectively reduce the TG. Contrasting to the results from chapter 6, magnitude of reduction in triglycerides in this study was higher with curcumin than LCn-3PUFA. Preliminary observations also presented a non-significant, but a noteworthy reduction of 0.5 mmol/L in total cholesterol and LDL-Cholesterol with curcumin supplementation. In line with observations from the COP-D trial, curcumin and LCn-3PUFA did not have any complimentary and/or added benefits. In conclusion, the results presented in this thesis demonstrate that InsuTAG has the potential to predict IR and MetS. This provides a basis for further research to validate InsuTAG with gold standard technique for IR and a longitudinal data analysis to determine the ability of InsuTAG to predict T2D in general population. With regards to the intervention trials, our hypothesis of targeting multiple pathways (IR and dyslipidaemia) in high risk and T2D patients with curcumin and LCn-3PUFA supplementation was successful. However, this thesis failed to provide any evidence on beneficial effects of combining curcumin and LCn-3PUFA for better glycaemic control to delay the onset of T2D. This could partly be due to presence of any unknown interactions between the two bio-actives or may be due to uncertainties in co-administration of curcumin and LCn-3PUFA. Thus, paving a way for further research to investigate beneficial effects with single formulation (curcumin and LCn-3PUFA) for achieving glycaemic control. This thesis constitutes a noted contribution to the research area of bio-markers and novel intervention strategies for T2D, and also presents a set of riddles that provides an extensive scope for future research.