Academic literature on the topic 'Polyfluorinated sulfonate'

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Journal articles on the topic "Polyfluorinated sulfonate"

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Lin, Qingqi, Can Zhou, Lei Chen, Yafei Li, Xiongfei Huang, Shizhong Wang, Rongliang Qiu, and Changyuan Tang. "Accumulation and associated phytotoxicity of novel chlorinated polyfluorinated ether sulfonate in wheat seedlings." Chemosphere 249 (June 2020): 126447. http://dx.doi.org/10.1016/j.chemosphere.2020.126447.

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Garmo, Laimar C., Mackenzie K. Herroon, Shane Mecca, Alexis Wilson, David R. Allen, Manisha Agarwal, Seongho Kim, Michael C. Petriello, and Izabela Podgorski. "The long-chain polyfluorinated alkyl substance perfluorohexane sulfonate (PFHxS) promotes bone marrow adipogenesis." Toxicology and Applied Pharmacology 491 (October 2024): 117047. http://dx.doi.org/10.1016/j.taap.2024.117047.

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Mao, Weili, Jianli Qu, Ruyue Guo, Yuanchen Chen, Hangbiao Jin, and Jingyan Xu. "Association between Serum 6:2 Chlorinated Polyfluorinated Ether Sulfonate Concentrations and Lung Cancer." Toxics 12, no. 8 (August 19, 2024): 603. http://dx.doi.org/10.3390/toxics12080603.

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6:2 chlorinated polyfluorinated ether sulfonate (6:2 Cl-PFESA) exhibits pronounced estrogenic effects, potentially influencing the etiology of lung cancer. This study assessed the potential associations between serum concentrations of 6:2 Cl-PFESA and lung cancer risk at the population level. Odds ratios (ORs) for lung cancer across serum 6:2 Cl-PFESA quartiles were assessed using conditional logistic regression. Additionally, we investigated potential effect modification by various confounding factors. Elevated serum levels of 6:2 Cl-PFESA were consistently associated with an increased risk of lung cancer in both the crude model (OR = 1.62, 95% CI: 1.08–2.42, p = 0.018) and the adjusted model (OR = 1.59, 95% CI: 1.06–2.39, p = 0.026). Stratified analyses revealed that elevated serum levels of 6:2 Cl-PFESA were associated with increased risk estimates of lung cancer among males (adjusted OR = 2.04, 95% CI: 1.19–3.51, p = 0.006), smokers (adjusted OR = 2.48, 95% CI: 1.25–4.89, p = 0.003), and drinkers (adjusted OR = 2.20, 95% CI: 0.94–5.16, p = 0.049). The results of this study imply that exposure to 6:2 Cl-PFESA at levels considered environmentally relevant may be linked to an elevated risk of developing lung cancer.
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Liu, Wei, Jingwen Li, Lichen Gao, Zhou Zhang, Jing Zhao, Xin He, and Xin Zhang. "Bioaccumulation and effects of novel chlorinated polyfluorinated ether sulfonate in freshwater alga Scenedesmus obliquus." Environmental Pollution 233 (February 2018): 8–15. http://dx.doi.org/10.1016/j.envpol.2017.10.039.

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Hong, So-Hye, Seung Hee Lee, Jun-Young Yang, Jin Hee Lee, Ki Kyung Jung, Ji Hyun Seok, Sung-Hee Kim, et al. "Orally Administered 6:2 Chlorinated Polyfluorinated Ether Sulfonate (F-53B) Causes Thyroid Dysfunction in Rats." Toxics 8, no. 3 (August 8, 2020): 54. http://dx.doi.org/10.3390/toxics8030054.

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The compound 6:2 chlorinated polyfluorinated ether sulfonate (F-53B), a replacement for perfluorooctanesulfonate (PFOS) in the electroplating industry, has been widely detected in numerous environmental matrices, human sera, and organisms. Due to regulations that limit PFOS use, F-53B use is expected to increase. Therefore, in this study, we performed a subchronic oral toxicity study of F-53B in Sprague Dawley (SD) rats. F-53B was administered orally once daily to male and female rats for 28 days at doses of 5, 20, and 100 mg/kg/day. There were no toxicologically significant changes in F-53B-treated rats, except in the thyroid gland. However, F-53B slightly reduced the serum concentrations of thyroid hormones, including triiodothyronine and thyroxine, compared with their concentrations in the vehicle group. F-53B also induced follicular hyperplasia and was associated with increased thyroid hormone biosynthesis-associated protein expression. These results demonstrate that F-53B is a strong regulator of thyroid hormones in SD rats as it disrupts thyroid function. Thus, caution should be exercised in the industrial application of F-53B as an alternative for PFOS.
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Pan, Ying, Bei Wen, Hongna Zhang, and Shuzhen Zhang. "Comparison of 6:2 chlorinated polyfluorinated ether sulfonate (6:2 Cl-PFESA) and perfluorooctane sulfonate (PFOS) accumulation and toxicity in mung bean." Environmental Pollution 287 (October 2021): 117332. http://dx.doi.org/10.1016/j.envpol.2021.117332.

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Shi, Guohui, Hua Guo, Nan Sheng, Qianqian Cui, Yitao Pan, Jinxing Wang, Yong Guo, and Jiayin Dai. "Two-generational reproductive toxicity assessment of 6:2 chlorinated polyfluorinated ether sulfonate (F-53B, a novel alternative to perfluorooctane sulfonate) in zebrafish." Environmental Pollution 243 (December 2018): 1517–27. http://dx.doi.org/10.1016/j.envpol.2018.09.120.

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Chu, Chu, Hao Ran, Yang Zhou, Kun Zhao, Yun-Ting Zhang, Yuan-Yuan Fan, Lu-Yin Wu, et al. "Placental inflammatory injury induced by chlorinated polyfluorinated ether sulfonate (F-53B) through NLRP3 inflammasome activation." Ecotoxicology and Environmental Safety 279 (July 2024): 116453. http://dx.doi.org/10.1016/j.ecoenv.2024.116453.

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Khazaee, Manoochehr, Emerson Christie, Weixiao Cheng, Mandy Michalsen, Jennifer Field, and Carla Ng. "Perfluoroalkyl Acid Binding with Peroxisome Proliferator-Activated Receptors α, γ, and δ, and Fatty Acid Binding Proteins by Equilibrium Dialysis with a Comparison of Methods." Toxics 9, no. 3 (February 26, 2021): 45. http://dx.doi.org/10.3390/toxics9030045.

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The biological impacts of per- and polyfluorinated alkyl substances (PFAS) are linked to their protein interactions. Existing research has largely focused on serum albumin and liver fatty acid binding protein, and binding affinities determined with a variety of methods show high variability. Moreover, few data exist for short-chain PFAS, though their prevalence in the environment is increasing. We used molecular dynamics (MD) to screen PFAS binding to liver and intestinal fatty acid binding proteins (L- and I-FABPs) and peroxisome proliferator activated nuclear receptors (PPAR-α, -δ and -γ) with six perfluoroalkyl carboxylates (PFCAs) and three perfluoroalkyl sulfonates (PFSAs). Equilibrium dissociation constants, KDs, were experimentally determined via equilibrium dialysis (EqD) with liquid chromatography tandem mass spectrometry for protein-PFAS pairs. A comparison was made between KDs derived from EqD, both here and in literature, and other in vitro approaches (e.g., fluorescence) from literature. EqD indicated strong binding between PPAR-δ and perfluorobutanoate (0.044 ± 0.013 µM) and perfluorohexane sulfonate (0.035 ± 0.0020 µM), and between PPAR-α and perfluorohexanoate (0.097 ± 0.070 µM). Unlike binding affinities for L-FABP, which increase with chain length, KDs for PPARs showed little chain length dependence by either MD simulation or EqD. Compared with other in vitro approaches, EqD-based KDs consistently indicated higher affinity across different proteins. This is the first study to report PPARs binding with short-chain PFAS with KDs in the sub-micromolar range.
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Liu, Wei, Hui Qin, Jingwen Li, Qian Zhang, Huanhuan Zhang, Zaoshi Wang, and Xin He. "Atmospheric chlorinated polyfluorinated ether sulfonate and ionic perfluoroalkyl acids in 2006 to 2014 in Dalian, China." Environmental Toxicology and Chemistry 36, no. 10 (April 21, 2017): 2581–86. http://dx.doi.org/10.1002/etc.3810.

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Dissertations / Theses on the topic "Polyfluorinated sulfonate"

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Fortin, Alice. "Οuverture de sultοnes par l'iοn fluοrure οu des réactifs pοlyfluοrés pοur le dévelοppement d'agents d'imagerie ΤEΡ et ΙRΜ." Electronic Thesis or Diss., Normandie, 2024. https://theses.hal.science/tel-04868295.

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Les travaux de cette thèse ont porté sur l’ouverture de sultones dans le cadre du développement de nouveaux agents de contraste polyfluorés amphiphiles pour l’Imagerie par Résonance Magnétique du fluor-19 (IRM du 19F). Dans une première partie, l’ouverture de sultones substituées par des nucléophiles oxygénés et azotés polyfluorés a été étudiée afin d’optimiser des conditions de synthèse d’agents de contraste dédiés à l’IRM du 19F. Dans une seconde partie, deux sultones polyfluorées ont été ouvertes par des ions [18F]fluorures, permettant d’obtenir des fluorosulfonates polyfluorés, conçus pour l’imagerie bimodale en IRM du 19F et Tomographie par Émission de Positons au fluor-18 (TEP)
This work focuses on the ring-opening of sultones in the development of new amphiphilic polyfluorinated contrast agents for fluorine-19 Magnetic Resonance Imaging (19F MRI). In the first part, the ring-opening of substituted sultones by oxygen and nitrogen polyfluorinated nucleophiles was studied to optimize synthesis conditions for contrast agents dedicated to 19F MRI. In the second part, two polyfluorinated sultones were opened by [18F]fluoride ions, resulting in polyfluorinated fluorosulfonates designed for bimodal imaging with 19F MRI and fluorine-18 Positron Emission Tomography (PET)
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Book chapters on the topic "Polyfluorinated sulfonate"

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Williams, Marc A. "Perfluorooctane Sulfonate (PFOS)." In Understanding Risk to Wildlife from Exposures to Per- and Polyfluorinated Alkyl Substances (PFAS), 53–104. First edition. | Boca Raton : CRC Press, 2021.: CRC Press, 2021. http://dx.doi.org/10.1201/9781003162476-3.

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Williams, Marc A. "Perfluorobutane Sulfonate (PFBS)." In Understanding Risk to Wildlife from Exposures to Per- and Polyfluorinated Alkyl Substances (PFAS), 111–24. First edition. | Boca Raton : CRC Press, 2021.: CRC Press, 2021. http://dx.doi.org/10.1201/9781003162476-7.

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Narizzano, Allison M. "Perfluorohexane Sulfonate (PFHxS)." In Understanding Risk to Wildlife from Exposures to Per- and Polyfluorinated Alkyl Substances (PFAS), 105–6. First edition. | Boca Raton : CRC Press, 2021.: CRC Press, 2021. http://dx.doi.org/10.1201/9781003162476-4.

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Narizzano, Allison M., and Michael J. Quinn. "6:2 Fluorotelomer Sulfonate (6:2 FTS)." In Understanding Risk to Wildlife from Exposures to Per- and Polyfluorinated Alkyl Substances (PFAS), 125–26. First edition. | Boca Raton : CRC Press, 2021.: CRC Press, 2021. http://dx.doi.org/10.1201/9781003162476-8.

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