Relevant bibliographies by topics / Point-of-Care (PoC)

Academic literature on the topic 'Point-of-Care (PoC)'

Author: Grafiati
Published: 10 December 2022
Last updated: 7 September 2023

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Contents

Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic 'Point-of-Care (PoC).'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Journal articles on the topic "Point-of-Care (PoC)"

1

Zubik, A. N., G. E. Rudnitskaya, A. A. Evstrapov, and T. A. Lukashenko. "POINT-OF-CARE (POC) DEVICES: CLASSIFICATION AND BASIC REQUIREMENTS." NAUCHNOE PRIBOROSTROENIE 32, no. 3 (August 30, 2022): 3–29. http://dx.doi.org/10.18358/np-32-3-i329.

Full text
Abstract:
The review presents the classification of point-of-care (POC) devices, and discusses the main characteristics of the devices and the requirements for them. The differences between the POC testing method and the laboratory method of analysis are considered. Examples of devices that fit the definition of POC for diagnosing infectious diseases are given.
APA, Harvard, Vancouver, ISO, and other styles
2

Weber, Christian Friedrich, Klaus Görlinger, Dirk Meininger, Eva Herrmann, Tobias Bingold, Anton Moritz, Lawrence H. Cohn, and Kai Zacharowski. "Point-of-Care Testing." Anesthesiology 117, no. 3 (September 1, 2012): 531–47. http://dx.doi.org/10.1097/aln.0b013e318264c644.

Full text
Abstract:
Introduction The current investigation aimed to study the efficacy of hemostatic therapy guided either by conventional coagulation analyses or point-of-care (POC) testing in coagulopathic cardiac surgery patients. Methods Patients undergoing complex cardiac surgery were assessed for eligibility. Those patients in whom diffuse bleeding was diagnosed after heparin reversal or increased blood loss during the first 24 postoperative hours were enrolled and randomized to the conventional or POC group. Thromboelastometry and whole blood impedance aggregometry have been performed in the POC group. The primary outcome variable was the number of transfused units of packed erythrocytes during the first 24 h after inclusion. Secondary outcome variables included postoperative blood loss, use and costs of hemostatic therapy, and clinical outcome parameters. Sample size analysis revealed a sample size of at least 100 patients per group. Results There were 152 patients who were screened for eligibility and 100 patients were enrolled in the study. After randomization of 50 patients to each group, a planned interim analysis revealed a significant difference in erythrocyte transfusion rate in the conventional compared with the POC group [5 (4;9) versus 3 (2;6) units [median (25 and 75 percentile)], P<0.001]. The study was terminated early. The secondary outcome parameters of fresh frozen plasma and platelet transfusion rates, postoperative mechanical ventilation time, length of intensive care unit stay, composite adverse events rate, costs of hemostatic therapy, and 6-month mortality were lower in the POC group. Conclusions Hemostatic therapy based on POC testing reduced patient exposure to allogenic blood products and provided significant benefits with respect to clinical outcomes.
APA, Harvard, Vancouver, ISO, and other styles
3

Wessels, Lars, Andreas Unterberg, and Christopher Beynon. "Point-of-Care Testing in Neurosurgery." Seminars in Thrombosis and Hemostasis 43, no. 04 (March 27, 2017): 416–22. http://dx.doi.org/10.1055/s-0037-1599159.

Full text
Abstract:
AbstractCoagulation disorders can have a major impact on the outcome of neurosurgical patients. The central nervous system is located within the closed space of the skull, and therefore, intracranial hemorrhage can lead to intracranial hypertension. Acute brain injury has been associated with alterations of various hemostatic parameters. Point-of-care (POC) techniques such as rotational thromboelastometry are able to identify markers of coagulopathy which are not reflected by standard assessment of hemostasis (e.g., hyperfibrinolysis). In patients with acute brain injury, POC test results have been associated with important outcome parameters such as mortality and need for neurosurgical intervention. POC devices have also been used to rapidly identify and quantify the effects of antithrombotic medication. In cases of life-threatening intracranial hemorrhage, this information can be valuable when deciding over administration of prohemostatic substances or immediate neurosurgical intervention. In elective neurosurgical procedures, POC devices can provide important information when unexpected bleeding occurs or in cases of prolonged operative time with subsequent blood loss. Initial experiences with POC devices in neurosurgical care have shown promising results but further studies are needed to characterize their full potential and limitations.
APA, Harvard, Vancouver, ISO, and other styles
4

Fries, Dietmar, and Werner Streif. "Point-of-Care Testing in Critically Ill Patients." Seminars in Thrombosis and Hemostasis 41, no. 01 (January 22, 2015): 075–83. http://dx.doi.org/10.1055/s-0035-1544184.

Full text
Abstract:
Point-of-care (POC) testing in hemostasis has experienced a significant increase in the spectrum of available tests and the number of tests performed. Short turn-around time and observation of rapid changes in test results are facilitated. The quality control process in POC testing must encompass a preanalytic (collection), analytic (measurement), and postanalytic (clinical response) phase. Erroneous interpretation of findings and difficult quality controls can outweigh the advantages of POC testing.Only a limited number of hemostatic POC tests have proven useful so far: prothrombin time POC—monitoring of oral vitamin K antagonists; activated clotting time POC—monitoring of high-dose heparin therapy; platelet function analyzer (PFA; Siemens, Marburg, Germany) closure time (CT)—detection of von Willebrand disease and severe platelet function defects; whole blood aggregometry (WBA) Multiplate (Roche Diagnostics, Rotkreuz, Switzerland), and the VerifyNow system (Accumetrics, San Diego, CA)—detection of platelet dysfunction due to antiplatelet drugs; thromboelastography—continuous observation of clot formation and fibrinolysis. The use of various agonists in WBA and thromboelastography (TEG) requires some expertise. In experienced hands the PFA CT and WBA and TEG are recommended combinations.Application of POC testing depends strictly on whether it improves medical care and patient outcome. More POC test systems are in the research pipeline, but only a few will resist the ravages of time.
APA, Harvard, Vancouver, ISO, and other styles
5

Tanaka, Kenichi, and Daniel Bolliger. "Point-of-Care Coagulation Testing in Cardiac Surgery." Seminars in Thrombosis and Hemostasis 43, no. 04 (March 30, 2017): 386–96. http://dx.doi.org/10.1055/s-0037-1599153.

Full text
Abstract:
AbstractBleeding complications after cardiac surgery are common and are associated with increased morbidity and mortality. Their etiology is multifactorial, and treatment decisions are time sensitive. Point-of-care (POC) testing has an advantage over standard laboratory tests for faster turn-around times, and timely decision on coagulation intervention(s). The most common POC coagulation testing is the activated clotting time (ACT), used to monitor heparin therapy while on cardiopulmonary bypass. Viscoelastic coagulation tests including thromboelastometry (ROTEM) and thromboelastography (TEG) have been recommended for the treatment of postoperative bleeding after cardiac surgery because the ROTEM/TEG-guided treatment algorithms reduced the use of blood products. Other POC tests are commercially available, but there is sparse evidence for their routine use in cardiac surgery. These devices include heparin management systems, POC prothrombin time and activated partial thromboplastin time, POC fibrinogen assay, and whole blood platelet function tests. There are multiple confounding elements and conditions associated with cardiac surgery, which can significantly alter test results. Anemia and thrombocytopenia are regularly associated with deviations in many POC devices. In summary, POC coagulation testing allows for rapid clinical decisions in hematological interventions, and, when used in conjunction with a proper transfusion algorithm, may reduce blood product usage, and potentially complications associated with blood transfusion.
APA, Harvard, Vancouver, ISO, and other styles
6

Drancourt, Michel, Audrey Michel-Lepage, Sylvie Boyer, and Didier Raoult. "The Point-of-Care Laboratory in Clinical Microbiology." Clinical Microbiology Reviews 29, no. 3 (March 30, 2016): 429–47. http://dx.doi.org/10.1128/cmr.00090-15.

Full text
Abstract:
SUMMARYPoint-of-care (POC) laboratories that deliver rapid diagnoses of infectious diseases were invented to balance the centralization of core laboratories. POC laboratories operate 24 h a day and 7 days a week to provide diagnoses within 2 h, largely based on immunochromatography and real-time PCR tests. In our experience, these tests are conveniently combined into syndrome-based kits that facilitate sampling, including self-sampling and test operations, as POC laboratories can be operated by trained operators who are not necessarily biologists. POC laboratories are a way of easily providing clinical microbiology testing for populations distant from laboratories in developing and developed countries and on ships. Modern Internet connections enable support from core laboratories. The cost-effectiveness of POC laboratories has been established for the rapid diagnosis of tuberculosis and sexually transmitted infections in both developed and developing countries.
APA, Harvard, Vancouver, ISO, and other styles
7

Stein, Philipp, Alexander Kaserer, Gabriela Spahn, and Donat Spahn. "Point-of-Care Coagulation Monitoring in Trauma Patients." Seminars in Thrombosis and Hemostasis 43, no. 04 (March 15, 2017): 367–74. http://dx.doi.org/10.1055/s-0037-1598062.

Full text
Abstract:
AbstractTrauma remains one of the major causes of death and disability all over the world. Uncontrolled blood loss and trauma-induced coagulopathy represent preventable causes of trauma-related morbidity and mortality. Treatment may consist of allogeneic blood product transfusion at a fixed ratio or in an individualized goal-directed way based on point-of-care (POC) and routine laboratory measurements. Viscoelastic POC measurement of the developing clot in whole blood and POC platelet function testing allow rapid and tailored coagulation and transfusion treatment based on goal-directed, factor concentrate–based algorithms. The first studies have been published showing that this concept reduces the need for allogeneic blood transfusion and improves outcome. This review highlights the concept of goal-directed POC coagulation management in trauma patients, introduces a selection of POC devices, and presents algorithms which allow a reduction in allogeneic blood product transfusion and an improvement of trauma patient outcome.
APA, Harvard, Vancouver, ISO, and other styles
8

Cozma, Angela, Camelia Vonica, Adela Sitar-Taut, and Adriana Fodor. "Point-of-care testing in diabetes management." Revista Romana de Medicina de Laborator 27, no. 2 (April 1, 2019): 125–35. http://dx.doi.org/10.2478/rrlm-2019-0014.

Full text
Abstract:
Abstract The prevalence of diabetes mellitus (DM) has rapidly increased over the last decades, reaching epidemic magnitudes, particularly in lowand middle-income countries. Point-of-care (POC) technology enables decision making near or at the site of patient care. Portable blood glucose meters and HbA1c testing are used by the healthcare provider and millions of patients with diabetes to monitor the safety and effectiveness of the diabetes treatment. However, POC capillary blood glucose and POC HbA1c testing are not recommended for diabetes diagnosis. Rather, they have been used for screening diabetes in lowand middle-income countries to decrease the disease burden.
APA, Harvard, Vancouver, ISO, and other styles
9

Chamane, Nkosinothando, Desmond Kuupiel, and Tivani Phosa Mashamba-Thompson. "Stakeholders’ Perspectives for the Development of a Point-of-Care Diagnostics Curriculum in Rural Primary Clinics in South Africa—Nominal Group Technique." Diagnostics 10, no. 4 (April 1, 2020): 195. http://dx.doi.org/10.3390/diagnostics10040195.

Full text
Abstract:
Poor knowledge and adherence to point-of-care (POC) HIV testing standards have been reported in rural KwaZulu-Natal (KZN), a high HIV prevalent setting. Improving compliance to HIV testing standards is critical, particularly during the gradual phasing out of lay counsellor providers and the shifting of HIV testing and counselling duties to professional nurses. The main objective of this study was to identify priority areas for development of POC diagnostics curriculum to improve competence and adherence to POC diagnostics quality standards for primary healthcare (PHC) nurses in rural South Africa. Method: PHC clinic stakeholders were invited to participate in a co-creation workshop. Participants were purposely sampled from each of the 11 KwaZulu-Natal Districts. Through the Nominal Group Technique (NGT), participants identified training related challenges concerning delivery of quality point of care diagnostics and ranked them from highest to lowest priority. An importance ranking score (scale 1–5) was calculated for each of the identified challenges. Results: Study participants included three PHC professional nurses, one TB professional nurse, one HIV lay councilor, one TB assistant and three POC diagnostics researchers, aged 23–50. Participants identified ten POC diagnostics related challenges. Amongst the highest ranked challenges were the following:absence of POC testing Curriculum for nurses, absence of training of staff on HIV testing and counselling as lay counsellor providers are gradually being phased out,. absence of Continuous Professional Development opportunities and lack of Staff involvement in POC Management programs. Conclusion: Key stakeholders perceived training of PHC nurses as the highest priority for the delivery of quality POC diagnostic testing at PHC level. We recommend continual collaboration among all POC diagnostics stakeholders in the development of an accessible curriculum to improve providers’ competence and ensure sustainable quality delivery of POC diagnostic services in rural PHC clinics.
APA, Harvard, Vancouver, ISO, and other styles
10

Straseski, Joely A., Martha E. Lyon, William Clarke, Jeffrey A. DuBois, Lois A. Phelan, and Andrew W. Lyon. "Investigating Interferences of a Whole-Blood Point-of-Care Creatinine Analyzer: Comparison to Plasma Enzymatic and Definitive Creatinine Methods in an Acute-Care Setting." Clinical Chemistry 57, no. 11 (November 1, 2011): 1566–73. http://dx.doi.org/10.1373/clinchem.2011.165480.

Full text
Abstract:
BACKGROUND Although measurement of whole-blood creatinine at the point of care offers rapid assessment of renal function, agreement of point-of-care (POC) results with central laboratory methods continues to be a concern. We assessed the influence of several potential interferents on POC whole-blood creatinine measurements. METHODS We compared POC creatinine (Nova StatSensor) measurements with plasma enzymatic (Roche Modular) and isotope dilution mass spectrometry (IDMS) assays in 119 hospital inpatients. We assessed assay interference by hematocrit, pH, pO2, total and direct bilirubin, creatine, prescribed drugs, diagnosis, red blood cell water fraction, and plasma water fraction. RESULTS CVs for POC creatinine were 1.5- to 6-fold greater than those for plasma methods, in part due to meter-to-meter variation. Regression comparison of POC creatinine to IDMS results gave a standard error (Sy|x) of 0.61 mg/dL (54 μmol/L), whereas regression of plasma enzymatic creatinine to IDMS was Sy|x 0.16 mg/dL (14 μmol/L). By univariate analysis, bilirubin, creatine, drugs, pO2, pH, plasma water fraction, and hematocrit were not found to contribute to method differences. However, multivariate analysis revealed that IDMS creatinine, red blood cell and plasma water fractions, and hematocrit explained 91.8% of variance in POC creatinine results. CONCLUSIONS These data suggest that whole-blood POC creatinine measurements should be used with caution. Negative interferences observed with these measurements could erroneously suggest adequate renal function near the decision threshold, particularly if estimated glomerular filtration rate is determined. Disparity between whole-blood and plasma matrices partially explains the discordance between whole-blood and plasma creatinine methods.
APA, Harvard, Vancouver, ISO, and other styles
More sources

Dissertations / Theses on the topic "Point-of-Care (PoC)"

1

Schenk, Sebastian [Verfasser]. "Vergleich von Point-of-Care (POC) Gerinnungsmessverfahren in der Kinderkardiochirurgie / Sebastian Schenk." Tübingen : Universitätsbibliothek Tübingen, 2020. http://d-nb.info/1219064793/34.

Full text
APA, Harvard, Vancouver, ISO, and other styles
2

Ruiz, Vega Gisela. "One-step electrochemical magneto assays for the development of point-of-care (POC) diagnostic devices." Doctoral thesis, Universitat Autònoma de Barcelona, 2019. http://hdl.handle.net/10803/669860.

Full text
Abstract:
Un dels majors reptes per a monitoritzar i millorar la salut de la població a nivell mundial és la manca de proves de diagnòstic apropiades per a la detecció primerenca de malalties, la selecció de tractaments apropiats i el seguiment de pacients al llarg del temps. La disponibilitat d’eines de diagnòstic prou ràpides, sensibles i robustes és crucial per aconseguir el benestar dels pacients a tot el món. En aquest context, la nanotecnologia i el desenvolupament de biosensors són camps en ràpida evolució que han generat grans expectatives, produint proves més ràpides i més fàcils de realitzar que la majoria dels mètodes clàssics. Els biosensors s’han descrit en base a l’ús d’una àmplia varietat d’elements de biotecnologia i tipus de transducció de senyals. Entre ells, els biosensors electroquímics són el tipus més comú en ús avui en dia gràcies a la portabilitat i el baix cost de l’equip de mesura, les mesures ràpides, robustes i quantitatives proporcionades, i la facilitat de miniaturització de tot el sistema de detecció. La recent incorporació de paper per a la producció d’elèctrodes impresos en paper i assajos electroquímics de flux lateral està fomentant el desenvolupament de dispositius extremadament econòmics que, gràcies a les propietats fluídicas del paper, permeten reduir la complexitat de l’assaig i el nivell de manipulació per al usuari final. Això afavoreix el desenvolupament de dispositius de diagnòstic de \”Point-of-care\” (POC), que poden ser utilitzats directament pel pacient o als centres d’atenció primària de salut. D’altra banda, les partícules magnètiques (PM) s’han utilitzat amb gran èxit en l’optimització dels magneto-biosensors. Les PM són atractives per a aquest propòsit perquè, un cop modificades amb un bioreceptor apropiat, atorguen una preconcentració simple, ràpida i específica de l’analit objectiu. Les PM també ofereixen superfícies actives en 3D relativament grans, que es barregen amb agitació constant amb les mostres i permeten una ràpida unió amb els analits. No obstant això, les PM també presenta limitacions, com el seu maneig tediós i lent que només està a l’abast d’usuaris altament capacitats. L’objectiu principal d’aquest projecte de tesi doctoral va ser la producció de magneto-biosensors electroquímics ràpids, fàcils de realitzar, robustos i sensibles per a la detecció de biomarcadors de diagnòstic en mostres de sèrum, plasma i sang. Com es mostrarà, això s’ha aconseguit en dos nivells. Primer, desenvolupant un format de magneto-immunoassaig extremadament ràpid i simple. En segon lloc, fabricant elèctrodes de paper microfluids simples i econòmics, que van ser explotats per dur a terme en el xip la majoria dels passos del magneto-immunoassaig simplificat amb la mínima intervenció de l’usuari.
Uno de los mayores desafíos para monitorear y mejorar la salud de la población a nivel mundial es la falta de pruebas de diagnóstico apropiadas para la detección temprana de enfermedades, la selección de tratamientos apropiados y el seguimiento de pacientes a lo largo del tiempo. La disponibilidad de herramientas de diagnóstico suficientemente rápidas, sensibles y robustas es crucial para lograr el bienestar de los pacientes en todo el mundo. En este contexto, la nanotecnología y el desarrollo de biosensores son campos en rápida evolución que han generado grandes expectativas, produciendo pruebas más rápidas y más fáciles de realizar que la mayoría de los métodos clásicos. Los biosensores se han descrito en base al uso de una amplia variedad de elementos de biotecnología y tipos de transducción de señales. Entre ellos, los biosensores electroquímicos son el tipo más común en uso hoy en día gracias a la portabilidad y el bajo costo del equipo de medición, las medidas rápidas, robustas y cuantitativas proporcionadas, y la facilidad de miniaturización de todo el sistema de detección. La reciente incorporación de papel para la producción de electrodos impresos en papel y ensayos electroquímicos de flujo lateral está fomentando el desarrollo de dispositivos extremadamente económicos que, gracias a las propiedades fluídicas del papel, permiten reducir la complejidad del ensayo y el nivel de manipulación para el usuario final. Esto favorece el desarrollo de dispositivos de diagnóstico de \”Point-of-care\” (POC), que pueden ser utilizados directamente por el paciente o en los centros de atención primaria de salud. Por otro lado, las partículas magnéticas (PM) se han utilizado con gran éxito en la optimización de los magneto-biosensores. Las PM son atractivos para este propósito porque, una vez modificados con un bioreceptor apropiado, otorgan una preconcentración simple, rápida y específica del analito objetivo. Las PM también ofrecen superficies activas en 3D relativamente grandes, que se mezclan bajo agitación constante con las muestras y permiten una rápida unión con los analitos. Sin embargo, las PM también presenta limitaciones, como su manejo tedioso y lento que solo está al alcance de usuarios altamente capacitados. El objetivo principal de este proyecto de tesis doctoral fue la producción de magneto-biosensores electroquímicos rápidos, fáciles de realizar, robustos y sensibles para la detección de biomarcadores de diagnóstico en muestras de suero, plasma y sangre. Como se mostrará, esto se ha logrado en dos niveles. Primero, desarrollando un formato de magneto-inmunoensayo extremadamente rápido y simple. En segundo lugar, fabricando electrodos de papel microfluidos simples y económicos, que fueron explotados para llevar a cabo en el chip la mayoría de los pasos del magneto-inmunoensayo simplificado con la mínima intervención del usuario.
One of the greatest challenges for monitoring and improving the health of the population at a global level is the lack of appropriate diagnostic tests for early detection of diseases, selection of appropriate treatments and patient follow-up over time. The availability of sufficiently fast, sensitive and robust diagnostic tools will be crucial to achieve patients’ well-being worldwide. In this context, nanotechnology and biosensor development are rapidly evolving fields that have generated great expectations, producing tests faster and easier to carry out than most classical methods. Biosensors have been described based on the use of a wide variety of biotechnology elements and types of signal transduction. Among them, electrochemical biosensors are the most common type in use today thanks to the portability and low cost of the measuring equipment, fast, robust and quantitative measures provided, and easiness of miniaturization of the whole detection system. The recent incorporation of paper and paper-like materials for the production of paper printed electrodes and lateral flow electrochemical assays is fostering the development of extremely inexpensive devices that, thanks to the fluidic properties of paper, allow reducing assay complexity and level of manipulation for the end user. This favours the development of "Point-of-Care" diagnostic devices (POC), which can be used directly by the patient or at primary health care centres. On the other hand, magnetic beads (MB) have been used with great success in the optimization of magneto-biosensors. MB are attractive for this purpose because, once modified with an appropriate bioreceptor, they grant simple, rapid and specific preconcentration of the targeted analyte. MB offer also relatively large 3D active surfaces, which mixed under constant agitation with the sample supply efficient and fast analyte binding as well. Nevertheless, MB display limitations too, requiring tedious and time-consuming handling that is only at reach of highly trained users. The main objective of this PhD Thesis project was the production of rapid, easy to perform, robust and sensitive electrochemical magneto-biosensors for the detection of diagnostic biomarkers in serum, plasma and blood samples. As it will be shown, this has been achieved at two levels. First, by developing an extremely fast and simple magnetoimmunoassay format. Second, by fabricating simple and inexpensive microfluidic paper electrodes, which were exploited to carry out on-chip most of the steps of the simplified magneto-immunoassay with minimal user intervention.
APA, Harvard, Vancouver, ISO, and other styles
3

Lightowler, Bryan, and Anthony Hoswell. "Can handheld POC capillary lactate measurement be used with arterial and venous laboratory testing methods in the identification of sepsis?" Mark Allen Group, 2016. http://hdl.handle.net/10454/18605.

Full text
Abstract:
No
The aim of this review was to examine whether the measurement of lactate in capillary blood samples using point-of-care handheld analysers corresponds sufficiently closely with arterial and venous whole-blood samples analysed by hospital central laboratory or blood gas analyser to be used interchangeably. A systematic search, informed by focused inclusion/exclusion criteria, was performed using multiple databases up to October 2015. A total of 65 articles were considered to have potential relevance and were evaluated in full text, of which ultimately five articles met all inclusion/exclusion criteria, and a final four were selected after data extraction and quality appraisal. All four studies found a predominantly upward bias in the measurement of lactate in capillary samples tested using a handheld point-of-care device over arterial or venous samples tested by laboratory methods or blood gas analyser. In terms of correlation, there was consensus between the studies that the strength of association between the two methods of measurement was statistically significant. Three studies directly examined the extent of agreement between point-of-care capillary lactate measurements and those of laboratory or blood gas analyser reference determined to ±2 standard deviations; 95% confidence intervals, and report contextually broad limits of agreement, identifying a potential for both over triage and, to a lesser extent, under triage. The findings of the review do not support interchangeable use of handheld fingertip point-of-care lactate measurement with laboratory or blood gas analyser methods in the identification of sepsis.
APA, Harvard, Vancouver, ISO, and other styles
4

Godfrey, Trevor M. "Going for Gold: Point of Care Bio-Diagnostics and Gold Nanoparticles Treating Disease." BYU ScholarsArchive, 2021. https://scholarsarchive.byu.edu/etd/8917.

Full text
Abstract:
Correct diagnosis of disease is essential in the effort to save and improve lives. Point of care (POC) diagnostics are in-vitro tests that assist in patient diagnosis and can be used at the location of patient care. POC diagnostics are easy to use and provide near-instant readouts allowing medical providers and patients to make rapid decisions about treatment. Increased access to POC testing is especially beneficial to low-income and low resource areas that cannot afford expensive lab testing. The World Health Organization (WHO) has outlined at least 113 diseases for which POC diagnostics are needed. Because of this, developing effective, efficient, and economical methods for creating new POC tests is essential. Work in section one of this thesis describes strategies by which new POC bio-diagnostics can be created. The use of oxidized cellulose as a vector for antibody immobilization was explored in several cellulose-based materials to provide quick, economical tests while still obtaining effective limits of detection when used to detect the pregnancy hormone Human Chorionic Gonadotropin (HCG) in a proof of concept study. The majority of these tests could detect as low as 100 ng/mL of HCG well below the clinical level necessary for detection at 2400 ng/mL. The use of a hand-powered syringe-based POC named the fast flow immunoassay (FFI) was tested for its ability to increase observable signal in a sandwich immunoassay by passing the sample through the test filter multiple times. 10 passes through the filter resulted in a signal approximately 17x more intense than a 1-hour dot-blot sandwich immunoassay. Both oxidized cotton and FFI systems can be used to develop new POC assays quickly and economically. Future use of these POC systems could help expand the availability of diagnostic testing to disadvantaged areas. Gold-based drugs have been used and investigated as medications multiple times throughout history to treat various diseases such as Rheumatoid arthritis, parasitic infections, and cancer. In the last few decades, gold nanoparticles have been used as drug delivery agents and catalysts for various reactions. Recently catalytic gold nanocrystals have been characterized for their ability to treat neurodegenerative diseases. Although these results were promising, much is still unknown about their mechanism of action. Section two of this thesis investigates potential molecular pathways that gold nanocrystals could be affecting, specifically the IL-6/Jak/STAT3 inflammation pathway and the Nrf2 antioxidant pathway. The gold nanocrystals we tested did not affect these pathways at physiologically obtainable concentrations. Additional work was done to characterize protein interactome or protein corona of gold nanocrystals. Preliminary proteomic characterization of this protein corona in fetal bovine serum (FBS) identified 118 potential interactors and classified those based on function and structure. Future work will need to be done to follow up on these identifications and to determine what mechanistic implications they may have.
APA, Harvard, Vancouver, ISO, and other styles
5

Emeka-Nweze, Chika Cornelia. "ICU_POC: AN EMR-BASED POINT OF CARE SYSTEM DESIGN FOR THE INTENSIVE CARE UNIT." Case Western Reserve University School of Graduate Studies / OhioLINK, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=case1499255523449397.

Full text
APA, Harvard, Vancouver, ISO, and other styles
6

Ferreira, Daniela Lina Alves. "Abordagem clínica de intoxicações em canídeos por inseticidas anticolinesterásicos e utilização de testes imediatos (point of care)." Master's thesis, Universidade de Lisboa. Faculdade de Medicina Veterinária, 2015. http://hdl.handle.net/10400.5/10489.

Full text
Abstract:
Dissertação de Mestrado Integrado em Medicina Veterinária
Perante a suspeita de intoxicação aguda, a abordagem célere e sistemática ao doente, permite uma rápida prestação de cuidados específicos. A triagem, recolha da história clínica, avaliação e intervenção médica de urgência, o diagnóstico e a terapêutica são processos chave nessa abordagem. O diagnóstico, por norma, é suportado por um painel analítico inicial. O recurso a testes imediatos (“point of care”), permite avaliar não só a condição geral dos doentes em tempo real, mas também os efeitos que os xenobióticos possam ter a nível orgânico e que se traduzam, nomeadamente, em alterações do equilíbrio hidroeletrólitico e estado ácido base. O presente estudo pretendeu avaliar as alterações analíticas, detetadas através da ferramenta ePOC (“Enterprise Point of Care”), em animais suspeitos de intoxicação por inseticidas anticolinesterásicos e a sua eventual influência no diagnóstico e implementação da terapêutica. A amostra estudada consistiu em 14 canídeos, que na triagem médica apresentavam sintomas inespecíficos e outros compatíveis com intoxicação aguda por insecticidas anticolinesterásicos: tremores musculares (93%), hipersiália (64%), hipertermia (57%), cianose (50%), diarreia (57%) e vómito (36%). Foram colhidas amostras de sangue para a realização do teste ePOC e para ulterior análise toxicológica.Os resultados obtidos através do ePOC mostraram diminuição da pressão parcial de dióxido de carbono (pCO2) (64%), aumento da concentração de lactato (36%), aumento dos valores de hemoglobina e hematócrito (50%), hiperglicémia (36%) e aumento dos valores de creatinina (50%), não havendo, contudo, relação estatisticamente significativa entre as variáveis testadas e o diagnóstico toxicológico (p>0.05). Porém, em todos os animais considerados acidémicos houve detecção de compostos do grupo dos inseticidas anticolinesterásicos na análise toxicológica. O estudo clínico individualizado de cada caso permitiu verificar que, apesar da sintomatologia similar, os animais apresentavam distúrbios ácido-base diferentes, sendo por isso também necessária uma abordagem terapêutica diferenciada, fulcral especialmente em condições críticas. Estudos futuros, com uma amostra de maior dimensão e preferencialmente com exposição a diferentes xenobióticos, poderão permitir uma avaliação mais exata e abrangente da relação entre a etiologia das intoxicações e as alterações hidroeletrolíticas e de gases sanguíneas verificadas.
ABSTRACT - Clinical Approach to Poisoning in Canidae by Anticholinesterase Insecticides and use of immediate tests (Point of Care) - Faced with a suspected acute intoxication, a prompt and systematic approach to the patient, allows a fast provision of specific care. The triage, history taking, assessment and emergency medical intervention, diagnosis and treatment are key processes in this approach. The diagnosis is usually supported by an initial analytic panel. The use of immediate testing ("point of care"), allows the evaluation, not only of the patient’s general condition in real time, but also the effects that xenobiotics may have at an organic level, which may result in electrolyte and acid base disorders. The presente study intended to evaluate the analytical changes detected by ePOC ("Enterprise Point of Care") in animals suspected of poisoning by anticholinesterase insecticides and their possible influence on the diagnostic and therapeutic implementation. The sample consisted of 14 canines, which had nonspecific symptoms and other compatible with acute poisoning by anticholinesterase insecticides: muscle tremors (93%), hypersialia (64%), fever (57%), cyanosis (50%), diarrhea (57%) and vomiting (36%). Blood samples were collect to perform ePOC testing and for further toxicological analysis. Analytical changes (ePOC) showed a decreased partial pressure of carbon dioxide (pCO2) (64%), an increased lactate concentration (36%), na increase in hemoglobin and hematocrit levels (50%), hyperglycemia (36%) and an increased serum creatinine values (50%), without, however, statistically significant relationship between the variables tested and toxicological diagnosis (p> 0.05). Nevertheless, in all animals considered acidemic, toxicological analysis showed the detection of anticholinesterase insecticides. The individualized clinical study of each case has shown, that despite the similar symptoms, the animals had different acid-base disorders and is, therefore, also required a different therapeutic approach, especially in critical conditions. Further studies with a larger sample and preferably with exposure to different xenobiotics may allow a more accurate and comprehensive evaluation of the relationship between the etiology of poisoning and blood gas and electrolyte changes observed.
APA, Harvard, Vancouver, ISO, and other styles
7

Oosthuizen, Louzanne. "A location science model for the placement of POC CD4 testing devices as part of South Africa's public healthcare diagnostic service delivery model." Thesis, Stellenbosch : Stellenbosch University, 2015. http://hdl.handle.net/10019.1/96972.

Full text
Abstract:
Thesis (MEng)--Stellenbosch University, 2015.
ENGLISH ABSTRACT: South Africa has a severe HIV (human immunodeficiency virus) burden and the management of the disease is a priority, especially in the public healthcare sector. One element of managing the disease, is determining when to initiate an HIV positive individual onto anti-retroviral therapy (ART), a treatment that the patient will remain on for the remainder of their lifetime. For the majority of HIV positive individuals in the country, this decision is governed by the results of a CD4 (cluster of differentiation 4) test that is performed at set time intervals from the time that the patient is diagnosed with HIV until the patient is initiated onto ART. A device for CD4 measurement at the point of care (POC), the Alere PIMA™, has recently become commercially available. This has prompted a need to evaluate whether CD4 testing at the POC (i.e. at the patient serving healthcare facility) should be incorporated into the South African public healthcare sector's HIV diagnostic service provision model. One challenge associated with the management of HIV in the country is the relatively large percentage of patients that are lost to follow-up at various points in the HIV treatment process. There is extensive evidence that testing CD4 levels at the POC (rather than in a laboratory, as is the current practice) reduces the percentage of patients that are lost to follow-up before being initiated onto ART. Therefore, though POC CD4 testing is more expensive than laboratory-based CD4 testing, the use of this technology in South Africa should be investigated for its potential to positively influence health outcomes. In this research, a multi-objective location science model is used to generate scenarios for the provision of CD4 testing capability. For each scenario, CD4 testing provision at 3 279 ART initiation facilities is considered. For each facility, either (i) a POC device is placed at the site; or (ii) the site's testing workload is referred to one of the 61 CD4 laboratories in the country. To develop this model, the characteristics of eight basic facility location models are compared to the attributes of the real-world problem in order to select the most suitable one for application. The selected model's objective, assumptions and inputs are adjusted in order to adequately model the realworld problem. The model is solved using the cross-entropy method for multi-objective optimisation and the results are verified using a commercial algorithm. Nine scenarios are selected from the acquired Pareto set for detailed presentation. In addition, details on the status quo as well as a scenario where POC testing is used as widely as possible are also presented. These scenarios are selected to provide decision-makers with information on the range of options that should be considered, from no or very limited use to widespread use of POC testing. Arguably the most valuable contribution of this research is to provide an indication of the optimal trade-off points between an improved healthcare outcome due to POC CD4 testing and increased healthcare spending on POC CD4 testing in the South African public healthcare context. This research also contributes to the location science literature and the metaheuristic literature.
AFRIKAANSE OPSOMMING: Suid-Afrika gaan gebuk onder `n swaar MIV- (menslike-immuniteitsgebreksvirus-) las en die bestuur van die siekte is `n prioriteit, veral in die openbare gesondheidsorgsektor. Een element in die bestuur van die siekte is om te bepaal wanneer `n MIV-positiewe individu met antiretrovirale- (ARV-)behandeling behoort te begin, waarop pasiënte dan vir die res van hul lewens bly. Vir die meeste MIV-positiewe individue in die land word hierdie besluit bepaal deur die uitslae van `n CD4- (cluster of differentiation 4-)toets wat met vasgestelde tussenposes uitgevoer word vandat die pasiënt met MIV gediagnoseer word totdat hy of sy met ARV-behandeling begin. `n Toestel vir CD4-meting by die punt van sorg (\POC"), die Alere PIMA™, is onlangs kommersieel beskikbaar gestel. Dit het `n behoefte laat ontstaan om te bepaal of CD4-toetsing by die POC (met ander woorde, by die gesondheidsorgfasiliteit waar die pasiënt bedien word) by die MIV-diagnostiese diensleweringsmodel van die Suid-Afrikaanse openbare gesondheidsorgsektor ingesluit behoort te word. Een uitdaging met betrekking tot MIV-bestuur in die land is die betreklik groot persentasie pasiënte wat verlore gaan vir nasorg in die verskillende stadiums van die MIV-behandelingsproses. Heelwat bewyse dui daarop dat die toetsing van CD4-vlakke by die POC (eerder as in `n laboratorium, soos wat tans die praktyk is) die persentasie pasiënte wat verlore gaan vir nasorg voordat hulle met ARV-behandeling kan begin, verminder. Daarom, hoewel CD4-toetsing by die POC duurder is as toetsing in `n laboratorium, behoort die gebruik van hierdie tegnologie in Suid-Afrika ondersoek te word. In hierdie studie is `n meerdoelige liggingswetenskapmodel gebruik om scenario's vir die voorsiening van CD4-toetsvermoë te skep. Vir elke scenario word CD4-toetsvermoë by 3 279 ARV-inisiasie fasiliteite oorweeg. Vir elke fasiliteit word toetsvermoë verskaf deur (i) die plasing van POC-toestelle by die fasiliteit, of (ii) verwysing vir laboratoriumgebaseerde toetsing by een van die 61 CD4-laboratoriums in die land. Die kenmerke van agt basiese fasiliteitsliggingsmodelle is met die kenmerke van die werklike probleem vergelyk om die mees geskikte model vir toepassing op die werklike probleem te bepaal. Die doelwitte, aannames en insette van die gekose model is daarna aangepas om die werklike probleem voldoende te modelleer. Die model is opgelos met behulp van die kruis-entropie-metode vir meerdoelige optimering, waarna die resultate deur middel van `n kommersiële algoritme bevestig is. Nege scenario's uit die verworwe Pareto-stel word uitvoerig aangebied. Daarbenewens beskryf die studieresultate die besonderhede van die status quo sowel as `n scenario waar POC-toetsing so wyd moontlik gebruik word. Hierdie scenario's word aangebied om besluitnemers van inligting te voorsien oor die verskeidenheid moontlikhede wat oorweeg kan word, wat wissel van geen of baie beperkte tot wydverspreide gebruik van POC-toetsing. Die mees beduidende bydrae van hierdie navorsing is stellig dat dit `n aanduiding bied van die optimale kompromie tussen `n verbeterde gesondheidsorguitkoms weens CD4-toetsing by die POC, en verhoogde gesondheidsorgbesteding aan CD4-toetsing by die POC, in die konteks van Suid-Afrikaanse openbare gesondheidsorg. Die navorsing dra ook by tot die ligingswetenskapliteratuur sowel as tot die metaheuristiekliteratuur.
APA, Harvard, Vancouver, ISO, and other styles
8

Azimi, Sayyed Mohamad. "Magnetic bead-based DNA extraction and purification microfluidic chip." Thesis, Brunel University, 2010. http://bura.brunel.ac.uk/handle/2438/4520.

Full text
Abstract:
A magnetic bead-based DNA extraction and purification device has been designed to be used for extraction of the target DNA molecules from whole blood sample. Mixing and separation steps are performed using functionalised superparamagnetic beads suspended in the cell lysis buffer in a circular chamber that is sandwiched between two electromagnets. Non-uniform nature of the magnetic field causes temporal and spatial distribution of the beads within the chamber. This process efficiently mixes the lysis buffer and whole blood in order to extract DNA from target cells. Functionalized surface of the magnetic beads then attract the exposed DNA molecules. Finally, DNA-attached magnetic beads are attracted to the bottom of the chamber by activating the bottom electrode. DNA molecules are extracted from the magnetic beads by washing and re-suspension processes. The numerical simulation approach has been adopted in order to design the magnetic field source. The performance of the magnetic field source has been investigated against different physical and geometrical parameters and optimised dimensions are obtained with two different magnetic field sources; integrated internal source and external source. A new magnetic field pattern has been introduced in order to efficiently control the bulk of magnetic beads inside the mixing chamber by dynamic shifting of magnetic field regions from the centre of the coils to the outer edge of the coils and vice versa. A Matlab code has been developed to simulate beads trajectories inside the designed extraction chip in order to investigate the efficiency of the magnetic mixing. A preliminary target molecule capturing simulation has also been performed using the simulated bead trajectories to evaluate the DNA-capturing efficiency of the designed extraction chip. The performance of the designed extraction chip has been tested by conducting a series of biological experiments. Different magnetic bead-based extraction kits have been used in a series of preliminary experiments in order to extract a more automation friendly extraction protocol. The efficiency of the designed device has been evaluated using the spiked bacterial DNA and non-pathogenic bacterial cell cultures (B. subtilis, Gram positive bacteria and E. coli, Gram negative bacteria) into the blood sample. Excellent DNA yields and recovery rates are obtained with the designed extraction chip through a simple and fast extraction protocol.
APA, Harvard, Vancouver, ISO, and other styles
9

Bjuhr, Mathias, Christian Berne, and Anders Larsson. "External Quality Assessment of HbA1c for Point of Care Testing." Thesis, Uppsala University, Department of Medical Biochemistry and Microbiology, 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-7850.

Full text
Abstract:

Objectives: To evaluate the long term total imprecision of HbA1c testing within the county of Uppsala in relation to the Swedish analytical goal of coefficient of variation (CV) <3% for HbA1c and to study the cost of an external quality assurance program for point-of-care HbA1c The county uses Bayer DCA 2000™ for point-of care HbA1c testing currently having 23 of these instruments.

Methods: Method imprecision was assessed by analysis of patient samples performed as split samples during a 3 year period (2002-2004) as part of the quality assurance program for point-of-care HbA1c testing. The samples were first analysed on a Bayer DCA 2000™ and the samples were then sent to the centralised laboratory for reanalysis with an HPLC system (Variant II™, Biorad). The testing was performed approximately 8 times per year with each instrument.

Results: The median CV between the HPLC method and the point-of-care instruments for each unit was slightly higher than 3%.

Conclusion: The DCA 2000™ systems have an acceptable imprecision and agreement with the central laboratory. The test results show acceptable agreements within the county regardless where the patient is tested. The cost of the external quality assurance program is calculated to be approximately SEK 1340 (Euro 150) per instrument.

APA, Harvard, Vancouver, ISO, and other styles
10

Aggarwal, Kashish. "An Android Based Portable Analyzer System for Point-of-care-testing(POCT) Immunodiagnostics." University of Cincinnati / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1543586356137427.

Full text
APA, Harvard, Vancouver, ISO, and other styles
More sources

Books on the topic "Point-of-Care (PoC)"

1

Medical Biosensors for Point of Care (POC) Applications. Elsevier, 2017. http://dx.doi.org/10.1016/c2014-0-01459-1.

Full text
APA, Harvard, Vancouver, ISO, and other styles
2

Narayan, Roger J. Medical Biosensors for Point of Care (POC) Applications. Elsevier Science & Technology, 2016.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
3

Narayan, Roger J. Medical Biosensors for Point of Care (POC) Applications. Elsevier Science & Technology, 2016.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
4

Implementation and Scale Up of Point of Care (POC) Diagnostics in Resource-Limited Settings. MDPI, 2020. http://dx.doi.org/10.3390/books978-3-03943-171-7.

Full text
APA, Harvard, Vancouver, ISO, and other styles
5

Morgan, Douglas E. Point-of-Care Testing (DRAFT). Edited by Raghavan Murugan and Joseph M. Darby. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190612474.003.0030.

Full text
Abstract:
Point-of-care testing (POCT) is defined as medical diagnostic testing performed outside the clinical laboratory in close proximity to where the patient is receiving care. POCT is typically performed by non-laboratory personnel and the results are used for clinical decision making. When used appropriately, point-of-care testing (POCT) is a valuable resource during the rapid response system (RRS) activation. Advantages include shortened time between acquiring a sample from the patient and analysis of that sample and a subsequent decrease in time to clinical decision making. Disadvantages revolve largely around the cost of POCT. Driving forces behind the movement towards POCT include care process optimization, improvement of patient outcomes, changing regulatory requirements, and changes in the face of the workforce.
APA, Harvard, Vancouver, ISO, and other styles
6

Xu, Tailin, and Yunlu Pan, eds. Integrated Point-of-care Testing (POCT) Systems: Recent Progress and Applications. Frontiers Media SA, 2022. http://dx.doi.org/10.3389/978-2-88974-739-9.

Full text
APA, Harvard, Vancouver, ISO, and other styles
7

Staff, IEEE. 2022 IEEE Healthcare Innovations and Point of Care Technologies (HI POCT). IEEE, 2022.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
8

Shephard OAM, Mark, ed. Practical Guide to Global Point-of-Care Testing. CSIRO Publishing, 2016. http://dx.doi.org/10.1071/9781486305193.

Full text
Abstract:
Point-of-care testing (POCT) refers to pathology testing performed in a clinical setting at the time of patient consultation, generating a rapid test result that enables informed and timely clinical action to be taken on patient care. It offers patients greater convenience and access to health services and helps to improve clinical outcomes. POCT also provides innovative solutions for the detection and management of chronic, acute and infectious diseases, in settings including family practices, Indigenous medical services, community health facilities, rural and remote areas and in developing countries, where health-care services are often geographically isolated from the nearest pathology laboratory. A Practical Guide to Global Point-of-Care Testing shows health professionals how to set up and manage POCT services under a quality-assured, sustainable, clinically and culturally effective framework, as well as understand the wide global scope and clinical applications of POCT. The book is divided into three major themes: the management of POCT services, a global perspective on the clinical use of POCT, and POCT for specific clinical settings. Chapters within each theme are written by experts and explore wide-ranging topics such as selecting and evaluating devices, POCT for diabetes, coagulation disorders, HIV, malaria and Ebola, and the use of POCT for disaster management and in extreme environments. Figures are included throughout to illustrate the concepts, principles and practice of POCT. Written for a broad range of practicing health professionals from the fields of medical science, health science, nursing, medicine, paramedic science, Indigenous health, public health, pharmacy, aged care and sports medicine, A Practical Guide to Global Point-of-Care Testing will also benefit university students studying these health-related disciplines.
APA, Harvard, Vancouver, ISO, and other styles

Book chapters on the topic "Point-of-Care (PoC)"

1

Lefebvre, Cedric W., Jay P. Babich, James H. Grendell, James H. Grendell, John E. Heffner, Ronan Thibault, Claude Pichard, et al. "Point of Care (POC) Coagulation Analyzers." In Encyclopedia of Intensive Care Medicine, 1785. Berlin, Heidelberg: Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-00418-6_3251.

Full text
APA, Harvard, Vancouver, ISO, and other styles
2

Vinayaka, Aaydha Chidambara, Than Linh Quyen, Mohsen Golabi, Trieu Nguyen, Van Ngoc Huynh, Dang Duong Bang, and Anders Wolff. "New-Generation Molecular Techniques in POC Biosensors for Detection of Infectious Diseases." In Nanobiosensors for point-of-care medical diagnostics, 79–106. Singapore: Springer Nature Singapore, 2022. http://dx.doi.org/10.1007/978-981-19-5141-1_4.

Full text
APA, Harvard, Vancouver, ISO, and other styles
3

Boldt, J. "Point-Of-Care (POC) Monitoring of Coagulation in the Critically Ill." In Yearbook of Intensive Care and Emergency Medicine, 570–76. Berlin, Heidelberg: Springer Berlin Heidelberg, 1999. http://dx.doi.org/10.1007/978-3-662-13453-5_49.

Full text
APA, Harvard, Vancouver, ISO, and other styles
4

Shekane, Paul. "Is Point-of-Care (POC) Coagulation Testing Worthwhile Before Regional or Neuraxial Anesthesia?" In You’re Wrong, I’m Right, 337–38. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-43169-7_97.

Full text
APA, Harvard, Vancouver, ISO, and other styles
5

Lewis, Gregory G., and Scott T. Phillips. "Quantitative Point-of-Care (POC) Assays Using Measurements of Time as the Readout: A New Type of Readout for mHealth." In Methods in Molecular Biology, 213–29. New York, NY: Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-2172-0_15.

Full text
APA, Harvard, Vancouver, ISO, and other styles
6

Muhammad, Imran, and Nilmini Wickramasinghe. "An Evaluation of the Point-of-Care (PoC) System Implementation and Adoption in a Multi-Campus Private Hospital in Melbourne." In Healthcare Delivery in the Information Age, 535–54. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-17347-0_26.

Full text
APA, Harvard, Vancouver, ISO, and other styles
7

Gässler, Norbert, Peter B. Luppa, Andreas Bietenbeck, Astrid Petersmann, Alexander Pröbstl, Daniel Romann, and Ralf Junker. "Implementation of POCT." In Point-of-Care Testing, 303–12. Berlin, Heidelberg: Springer Berlin Heidelberg, 2018. http://dx.doi.org/10.1007/978-3-662-54497-6_31.

Full text
APA, Harvard, Vancouver, ISO, and other styles
8

Bietenbeck, Andreas, and Siegfried Jedamzik. "POCT in telemedicine." In Point-of-Care Testing, 333–36. Berlin, Heidelberg: Springer Berlin Heidelberg, 2018. http://dx.doi.org/10.1007/978-3-662-54497-6_35.

Full text
APA, Harvard, Vancouver, ISO, and other styles
9

Vashist, Sandeep K., John H. T. Luong, Peter B. Luppa, and Ralf Junker. "Future POCT systems." In Point-of-Care Testing, 413–20. Berlin, Heidelberg: Springer Berlin Heidelberg, 2018. http://dx.doi.org/10.1007/978-3-662-54497-6_41.

Full text
APA, Harvard, Vancouver, ISO, and other styles
10

Luppa, Peter B., Christoph Braun, and Andreas Bietenbeck. "POCT and data management." In Point-of-Care Testing, 269–79. Berlin, Heidelberg: Springer Berlin Heidelberg, 2018. http://dx.doi.org/10.1007/978-3-662-54497-6_27.

Full text
APA, Harvard, Vancouver, ISO, and other styles

Conference papers on the topic "Point-of-Care (PoC)"

1

Sibbitt, John P., and Mei He. "3D Printing of Microfluidics for Point of Care Diagnosis." In ASME 2017 12th International Manufacturing Science and Engineering Conference collocated with the JSME/ASME 2017 6th International Conference on Materials and Processing. American Society of Mechanical Engineers, 2017. http://dx.doi.org/10.1115/msec2017-2778.

Full text
Abstract:
Microfluidic lab-on-a-chip (MLOC) technology is a promising approach for point-of-care (POC) diagnosis; low reagent consumption, high sensitivity and quick analysis time are the most prominent benefits. However, microfabrication of MLOCs utilizes specialized techniques and infrastructure, making conventional fabrication time consuming and difficult. While relatively inexpensive production techniques exist for POC diagnoses, such as replication of polymer-based (e.g., PDMS) microfluidic POC devices on lithographic molds, this approach has limitations including: further hydrophilic surface modifications of PDMS, inability to change lithographic mold Z dimensions, and slow prototyping. In contrast, stereo-lithographical (SLA) printing can integrate all of the necessary fabrication resources in one instrument, allowing highly versatile microfluidic devices to be made at low cost. In this paper, we report two microfabrication approaches of microfluidics utilizing (SLA) 3D printing technology: I) Direct SLA printing of channels and structures of a monolithic microfluidic POC device; II) Indirect fabrication, utilizing SLA 3D printed molds for PDMS based microfluidic device replication. Additionally, we discuss previous work providing a proof of concept of applications in POC diagnosis, using direct 3D printing fabrication (approach I). The robustness and simplicity of these protocols allow integrating 3D design and microfabrication with smartphone-based disease diagnosis as a stand-alone system, offering strong adaptability for establishing diagnostic capacity in resource-limited areas and low-income countries.
APA, Harvard, Vancouver, ISO, and other styles
2

Leary, James F. "Design of point-of-care (POC) microfluidic medical diagnostic devices." In Microfluidics, BioMEMS, and Medical Microsystems XVI, edited by Bonnie L. Gray and Holger Becker. SPIE, 2018. http://dx.doi.org/10.1117/12.2286542.

Full text
APA, Harvard, Vancouver, ISO, and other styles
3

Martínez-López, J. Israel, Mauricio Mojica, H. A. Betancourt, Ciro A. Rodríguez, and Héctor R. Siller. "Xurography and Lamination for Manufacturing Point-of-Care (POC) Micromixers." In 4M/IWMF2016 The Global Conference on Micro Manufacture : Incorporating the 11th International Conference on Multi-Material Micro Manufacture (4M) and the 10th International Workshop on Microfactories (IWMF). Singapore: Research Publishing Services, 2016. http://dx.doi.org/10.3850/978-981-11-0749-8_722.

Full text
APA, Harvard, Vancouver, ISO, and other styles
4

Perumal, Jayakumar, Ran Zhi Tong Chua, Mohesh Moothanchery, Poongkulali Rajarahm, Aniza Puteri Mahyuddin, Ghayathri Balasundaram, Mahesh Choolani, and Malini Olivo. "Rapid and sensitive detection of disease biomarkers using SERS assay in a simplified Raman POC device." In Optical Diagnostics and Sensing XXIII: Toward Point-of-Care Diagnostics, edited by Gerard L. Coté. SPIE, 2023. http://dx.doi.org/10.1117/12.2664254.

Full text
APA, Harvard, Vancouver, ISO, and other styles
5

Tanke, Hans J., Michel Zuiderwijk, Karien C. Wiesmeijer, Robert N. Breedveld, William R. Abrams, Claudia J. de Dood, Elisa M. Tjon Kon Fat, and Paul L. A. M. Corstjens. "The use of upconverting phosphors in point-of-care (POC) testing." In SPIE BiOS, edited by Daniel L. Farkas, Dan V. Nicolau, and Robert C. Leif. SPIE, 2014. http://dx.doi.org/10.1117/12.2036906.

Full text
APA, Harvard, Vancouver, ISO, and other styles
6

Jiang, Yu, Jayne Wu, and Shigetoshi Eda. "A Rapid and Ultra-sensitive Sensing Strategy based on Tunable Dielectrophoresis for Robust POC Detection." In 2022 IEEE Healthcare Innovations and Point of Care Technologies (HI-POCT). IEEE, 2022. http://dx.doi.org/10.1109/hi-poct54491.2022.9744059.

Full text
APA, Harvard, Vancouver, ISO, and other styles
7

Varadan, Vijay K. "Nanotechnology Based Point-of-Care Diagnostics and Therapeutics for Neurological Disorders." In ASME 2010 First Global Congress on NanoEngineering for Medicine and Biology. ASMEDC, 2010. http://dx.doi.org/10.1115/nemb2010-13014.

Full text
Abstract:
This talk is aimed at presenting novel solutions developed recently by the author’s group for many neurological disorders including Parkinson’s disease, Alzheimer’s disease, depression, anxiety, sleep apnea and sleep disorders using the fundamental research and developments in nanotechnologies and wireless sensor network. Point-of-care (POC) diagnostics promises to bring diagnostic testing out of the laboratory directly to patients and the general public wherever they may be. The key to POC diagnostics is capable of bringing immediate answers so that health care professionals can make rapid and accurate diagnosis of disease so as to ensure the effectiveness of therapy and early detection for preventive therapy. Selected movies illustrating the applications of both invasive and non-invasive wireless nanosensor systems to patients and surgical procedures will be shown at the talk.
APA, Harvard, Vancouver, ISO, and other styles
8

Kasparick, Martin, Frank Golatowski, and Dirk Timmermann. "A safe and interoperable distributed alarm notification system for PoC medical devices using IEEE 11073 SDC." In 2017 IEEE Healthcare Innovations and Point-of-Care Technologies (HI-POCT). IEEE, 2017. http://dx.doi.org/10.1109/hic.2017.8227633.

Full text
APA, Harvard, Vancouver, ISO, and other styles
9

Cheng, Yu-Hsuan, Charmi Chande, Li Zhenglong, Sreerag Kaaliveetil, and Sagnik Basuray. "Sensitive and Selective Determination of multiple Diagnostic Targets using a Modular, ASSURED POC Platform called ESSENCE." In 2022 IEEE Healthcare Innovations and Point of Care Technologies (HI-POCT). IEEE, 2022. http://dx.doi.org/10.1109/hi-poct54491.2022.9744075.

Full text
APA, Harvard, Vancouver, ISO, and other styles
10

Hsu, Chia-Hao, Yue-Da Tsai, Yun-Chi Chen, Ming-Chih Lee, I.-Yu Huang, and Chua-Chin Wang. "A fast FPW allergy analyzer prototype for point of care (POC)." In 2012 IEEE International Conference on Consumer Electronics (ICCE). IEEE, 2012. http://dx.doi.org/10.1109/icce.2012.6161803.

Full text
APA, Harvard, Vancouver, ISO, and other styles
You might also be interested in the extended bibliographies on the topic 'Point-of-Care (PoC)' for particular source types:
Journal articles Dissertations / Theses
We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!

To the bibliography