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1

Lee, Kenneth Robert. "Pneumonectomy." Chest 134, no. 6 (December 2008): 1347. http://dx.doi.org/10.1378/chest.08-1500.

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Zhao, Jasmine, Alexandra Nguyen, Li Ding, Elizabeth A. David, Scott M. Atay, Sean C. Wightman, P. Michael McFadden, and Anthony W. Kim. "Trends in pneumonectomy for treatment of small-cell lung cancer." Asian Cardiovascular and Thoracic Annals 28, no. 9 (September 2, 2020): 583–91. http://dx.doi.org/10.1177/0218492320955054.

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Background According to practice guidelines, patients with clinical stage T1–2 node-negative small-cell lung cancer are candidates for surgical resection. However, the role of pneumonectomy in small-cell lung cancer patients is not well understood. The objective of this study was to assess the extent to which pneumonectomy is used and to evaluate the survival implications for small-cell lung cancer patients who underwent pneumonectomy. Methods A total of 106 small-cell lung cancer patients who underwent pneumonectomy between 2006 and 2016 and met the study criteria were identified in the National Cancer Database. Demographics and treatment regimens are described, and overall survival was assessed using Kaplan-Meier and log-rank tests. Results The most common treatment was surgery with adjuvant chemotherapy, followed by surgery only and surgery with neoadjuvant therapy. The 5-year overall survival for the entire cohort after pneumonectomy was 23%. In subgroup analysis, the 5-year overall survival was 30% for guideline-concordant clinical stage I patients and 28% for clinical stage II/III patients who underwent pneumonectomy. There was no statistical difference in survival according to pathologic N disease. Patients with a right-sided pneumonectomy had higher mortality than patients with a left-sided pneumonectomy. Conclusions This study suggests a role for pneumonectomy in clinical stage I and potentially some clinical stage II and III small-cell lung cancer patients. Right-sided pneumonectomy is associated with higher mortality and should be approached with caution. Despite declining trends over the past decades, pneumonectomy is still an effective treatment that is able to achieve acceptable survival outcomes.
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3

Kim, Noheul, and Ronny Priefer. "Drug Regimen for Patients after a Pneumonectomy." Journal of Respiration 1, no. 2 (April 13, 2021): 114–34. http://dx.doi.org/10.3390/jor1020013.

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Pneumonectomy is an entire lung removal and is indicated for both malignant and benign diseases. Due to its invasiveness and postoperative complications, pneumonectomy is still associated with high mortality and morbidity. Appropriate postoperative management is crucial in pneumonectomy patients to improve quality of life and overall survival rates. Diverse drug regimens are under development to be used in adjuvant chemotherapy or to improve respiratory health after a pneumonectomy. The most common causes for a pneumonectomy are non-small cell lung cancer, malignant pleural mesothelioma, and tuberculosis; thus, an appropriate drug regimen is necessary. The uncommon incidence of pneumonectomy cases remains the major obstacle in studies of postoperative drug regimens. As the majority of current studies include post-lobectomy and post-segmentectomy patients, it is highly recommended that further research of postoperative drug regimens be focused on post-pneumonectomy patients.
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Galetta, Domenico, and Lorenzo Spaggiari. "Robotic pneumonectomy." Shanghai Chest 5 (January 2021): 6. http://dx.doi.org/10.21037/shc.2020.04.01.

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Avella Patino, Diego, and Mark K. Ferguson. "Right pneumonectomy." Shanghai Chest 1 (2017): 10. http://dx.doi.org/10.21037/shc.2017.05.08.

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6

Galetta, Domenico, and Lorenzo Spaggiari. "Extrapleural pneumonectomy." Shanghai Chest 1 (2017): 32. http://dx.doi.org/10.21037/shc.2017.08.13.

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7

Thirugnanam, Agasthian. "Completion pneumonectomy." ASVIDE 3 (December 2016): 518. http://dx.doi.org/10.21037/asvide.2016.518.

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8

Royo-Crespo, Iñigo, Arthur Vieira, and Paula A. Ugalde. "Right pneumonectomy." ASVIDE 5 (March 2018): 179. http://dx.doi.org/10.21037/asvide.2018.179.

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9

Aigner, Clemens, Gyoergy Lang, and Walter Klepetko. "Sleeve Pneumonectomy." Seminars in Thoracic and Cardiovascular Surgery 18, no. 2 (June 2006): 109–13. http://dx.doi.org/10.1053/j.semtcvs.2006.05.005.

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10

Qadri, Syed S. A., Alex Cale, Mahmoud Loubani, Mubarak Chaudhry, and Michael Cowen. "Extrapleural Pneumonectomy." PLEURA 2 (July 21, 2015): 237399751559521. http://dx.doi.org/10.1177/2373997515595219.

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11

Andrews, Penny L., and Nader M. Habashi. "Understanding pneumonectomy." OR Nurse 3, no. 2 (March 2009): 32–39. http://dx.doi.org/10.1097/01.orn.0000347325.89970.be.

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&NA;. "Understanding pneumonectomy." OR Nurse 3, no. 2 (March 2009): 39–40. http://dx.doi.org/10.1097/01.orn.0000347326.28089.37.

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13

Chawla, Mohit, Todd Getzen, and Michael J. Simoff. "Medical Pneumonectomy." Chest 135, no. 5 (May 2009): 1355–58. http://dx.doi.org/10.1378/chest.08-2091.

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14

Hendriks, J., P. Lauwers, and P. Van Schil. "Extrapericardial pneumonectomy." Multimedia Manual of Cardio-Thoracic Surgery 2005, no. 0628 (January 1, 2005): 0083–0. http://dx.doi.org/10.1510/mmcts.2004.000083.

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15

Slinger, Peter. "Sleeve Pneumonectomy." Journal of Cardiothoracic and Vascular Anesthesia 23, no. 2 (April 2009): 269–70. http://dx.doi.org/10.1053/j.jvca.2008.02.009.

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16

Louie, Brian E. "Robotic Pneumonectomy." Thoracic Surgery Clinics 24, no. 2 (May 2014): 169–75. http://dx.doi.org/10.1016/j.thorsurg.2014.02.007.

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17

Mehran, Reza, and Jean Deslauriers. "Carinal Pneumonectomy." Thoracic Surgery Clinics 28, no. 3 (August 2018): 315–22. http://dx.doi.org/10.1016/j.thorsurg.2018.04.004.

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18

Szarnicki, Robert J. "Neonatal pneumonectomy." Annals of Thoracic Surgery 53, no. 3 (March 1992): 547. http://dx.doi.org/10.1016/0003-4975(92)90302-k.

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19

Battoo, Athar, Ariba Jahan, Zhengyu Yang, Chukwumere E. Nwogu, Sai S. Yendamuri, Elisabeth U. Dexter, Mark W. Hennon, Anthony L. Picone, and Todd L. Demmy. "Thoracoscopic Pneumonectomy." Chest 146, no. 5 (November 2014): 1300–1309. http://dx.doi.org/10.1378/chest.14-0058.

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20

Deslauriers, Jean, Jocelyn Grégoire, Louis F. Jacques, and Michel Piraux. "Sleeve pneumonectomy." Thoracic Surgery Clinics 14, no. 2 (May 2004): 183–90. http://dx.doi.org/10.1016/s1547-4127(04)00012-x.

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21

Cleveland, David C. "Neonatal pneumonectomy." Annals of Thoracic Surgery 56, no. 3 (September 1993): 596–97. http://dx.doi.org/10.1016/0003-4975(93)90924-7.

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22

Beck, Naomi, Thomas J. van Brakel, Hans J. M. Smit, David van Klaveren, Michel W. J. M. Wouters, and Wilhelmina H. Schreurs. "Pneumonectomy for Lung Cancer Treatment in The Netherlands: Between-Hospital Variation and Outcomes." World Journal of Surgery 44, no. 1 (September 23, 2019): 285–94. http://dx.doi.org/10.1007/s00268-019-05190-w.

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Abstract Background Pneumonectomy in lung cancer treatment is associated with considerable morbidity and mortality. Its use is reserved only for patients in whom a complete oncological resection by (sleeve) lobectomy is not possible. It is unclear whether a patients’ risk of receiving a pneumonectomy is equally distributed. This study examined between-hospital variation of pneumonectomy use for primary lung cancer in the Netherlands. Methods Data from the Dutch Lung Cancer Audit for Surgery from 2012 to 2016 were used to study the use of pneumonectomy for primary lung cancer in the Netherlands. Using multivariable logistic regression, factors associated with pneumonectomy use were identified and the expected number of pneumonectomies per hospital was determined. Subsequently, the observed/expected ratio (O/E ratio) per hospital was calculated to study between-hospital differences. Results Of the 8446 included patients, 659 (7.8%) underwent a pneumonectomy with a mean postoperative mortality of 7.1% (n = 47). Factors associated with receiving a pneumonectomy were age, gender, cardiac and pulmonary comorbidities, tumor side, size and histopathology. The pneumonectomy use in the Netherlands varied considerably between hospitals (IQR 5.5–10.1%). Three hospitals out of 51 performed significantly less pneumonectomies than expected (O/E ratio < 0.5) and three significantly more (O/E ratio > 1.7). In the latter group, severe complications were more frequent, taking other influencing factors into account (OR 1.51, 95% CI 1.05–2.19). Conclusions There is a considerable between-hospital variation in pneumonectomy use in lung cancer treatment. To further optimize surgical lung cancer care, we suggest center-specific feedback on pneumonectomy use and the development of a risk-adjusted pneumonectomy indicator.
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23

Hsia, C. C., J. I. Carlin, S. S. Cassidy, M. Ramanathan, and R. L. Johnson. "Hemodynamic changes after pneumonectomy in the exercising foxhound." Journal of Applied Physiology 69, no. 1 (July 1, 1990): 51–57. http://dx.doi.org/10.1152/jappl.1990.69.1.51.

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Pulmonary arterial pressure is higher during exercise after pneumonectomy than before. Several factors may contribute to the elevation, e.g., loss of vascular bed, overinflation of the remaining lung, and active pulmonary vasoconstriction. We measured hemodynamic changes during graded exercise in conditioned foxhounds and compared pulmonary pressure-flow relationships before and after left pneumonectomy. Pulmonary arterial pressure-flow relationship in the remaining lung is not altered by pneumonectomy, suggesting that the increase in pulmonary vascular resistance post-pneumonectomy is largely the passive consequence of increased pulmonary blood flow to the remaining lung. The potential for chronic hyperinflation of the remaining lung to increase pulmonary resistance after pneumonectomy may have been counterbalanced by a concomitant reduction in lung elastic recoil. Unexpectedly, both mean systemic blood pressure and hematocrit were higher with respect to cardiac output after pneumonectomy. Cardiac output and stroke volume at any given work load were lower after pneumonectomy than before, and heart rate response was unaltered. This pattern of responses suggests that increases in left and right ventricular afterload may have contributed to the reduction in cardiac output.
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Carlin, J. I., C. C. Hsia, S. S. Cassidy, M. Ramanathan, P. S. Clifford, and R. L. Johnson. "Recruitment of lung diffusing capacity with exercise before and after pneumonectomy in dogs." Journal of Applied Physiology 70, no. 1 (January 1, 1991): 135–42. http://dx.doi.org/10.1152/jappl.1991.70.1.135.

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Although the left lung constitutes 42% of the total by weight and volume in dogs, carbon monoxide diffusing capacity (DL) after left pneumonectomy in adults falls less than 30% at rest, indicating a significant increase of DL in the remaining lung. DL normally increases during exercise, presumably by recruitment of alveolar capillaries and surface area as lung volume (Vs) and pulmonary blood flow (Qc) increase. We asked whether the increase of DL in the remaining lung after pneumonectomy in adult dogs could be explained by this kind of passive recruitment by the increased volume and Qc in the remaining lung. We measured the relationship between DL and Qc with a rebreathing technique at increasing treadmill loads in adult foxhounds, before and 6 mo after left pneumonectomy, and the relationship between DL and Vs by the same technique under anesthesia as Vs was expanded. DL was reduced by 29.1% at rest and 26.5% with heavy exercise after left pneumonectomy, indicating either recruitment or new growth in the right lung. With the assumption that the right lung normally receives 58% of the Qc and contains 58% of the DL, DL of the right lung increased with Qc in accordance with the following relationships before and after left pneumonectomy: right lung DL (before pneumonectomy) = 6.44 + 2.40(Qc) (r = 0.963) and right lung DL (after pneumonectomy) = 7.51 + 1.75(Qc) (r = 0.958). Only approximately 7% of the increase in DL from rest to peak exercise could be attributed to the increase in Vs during exercise before pneumonectomy and approximately 15% after pneumonectomy.(ABSTRACT TRUNCATED AT 250 WORDS)
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25

Li, Yuping, Gening Jiang, Chang Chen, and Xuefei Hu. "Pneumonectomy for Treatment of Destroyed Lung: A Retrospective Study of 137 Patients." Thoracic and Cardiovascular Surgeon 65, no. 07 (May 13, 2016): 528–34. http://dx.doi.org/10.1055/s-0036-1583524.

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Objectives Whether pneumonectomy is needed for the treatment of destroyed lungs is still controversial and unresolved in the clinic. Pneumonectomy is destructive and is associated with a significant incidence of postoperative complications. The purpose of this study is to analyze the operative techniques, postoperative morbidity, mortality, and long-term outcomes of patients with destroyed lungs who underwent pneumonectomy. Patients and Methods We retrospectively analyzed 137 patients with destroyed lungs who underwent pneumonectomy. The data were queried for the details of operative technique, development of perioperative complications, mortality, and long-term survival. Univariate and multivariate analyses were performed to investigate the risk factors of pneumonectomy among the patients. Results A total of 77 male and 60 female patients were reviewed. The youngest patient was 18 years, and the oldest was 75 years, with a mean age of 40.1 years. Postoperative complications were observed in 25 patients (18.2%). The rate of bronchopleural fistula (BPF) was 5.1% (7/137). Two perioperative deaths (1.5%) were noted. Univariate and multivariate analyses indicated the blood loss (hazard ratio [HR], 5.32; 95% confidence interval [CI], 1.27–18.50; p = 0.021) was the independent risk factor of postoperative complications, and the type of the disease (HR, 4.50; 95% CI, 1.19–9.69; p = 0.034) was the independent risk factor of the BPF, for the patients with destroyed lung after pneumonectomy. Conclusion Pneumonectomy for destroyed lung is a high risk for postoperative complications. Our findings suggested that pneumonectomy in destroyed lung was satisfactory with strict surgical indications, adequate preoperative preparation, and careful operative technique, and the long-term outcomes can be especially satisfactory. Pneumonectomy for destroyed lung is still a treatment option.
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Bölükbas, Servet, Robert Zanner, Michael Eberlein, Christian Biancosino, and Bassam Redwan. "Secondary Lingular Sleeve Resection to Avoid Pneumonectomy Following Bronchial Anastomotic Dehiscence after Left Lower Lobe Sleeve Resection for Destroyed Lung Syndrome." Surgery Journal 04, no. 01 (January 2018): e14-e17. http://dx.doi.org/10.1055/s-0038-1635124.

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AbstractBronchial sleeve resections are technically demanding procedures compared with lobectomies. In case of bronchial anastomotic dehiscence, secondary pneumonectomy is the treatment of choice. However, a secondary pneumonectomy is usually associated with high morbidity and mortality. Here, we first report, to the best of our knowledge, a secondary lingular sleeve resection following bronchial anastomotic dehiscence after left lower lobe sleeve resection in a patient with a destroyed lobe syndrome due to a pseudotumor. This approach enabled the avoidance of secondary pneumonectomy, hence reducing the possible pneumonectomy-associated complications.
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Yuequan, Jiang, Zhang Zhi, and Xie Chenmin. "Surgical Resection for Small Cell Lung Cancer: Pneumonectomy versus Lobectomy." ISRN Surgery 2012 (May 30, 2012): 1–6. http://dx.doi.org/10.5402/2012/101024.

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Background. There are some patients with SCLC that are diagnosed in the operating room by cryosection and surgeons had to perform surgical resection for these patients. The aim of this study is to compare the effective of pneumonectomy with lobectomy for SCLC. Methods. A retrospective study was undertaken in 75 patients with SCLC that were diagnosed by cryosection during surgery. 31 of them underwent pneumonectomy, 44 underwent lobectomy. Local recurrence rate and survival rate according to surgical procedures and cancer stages were analyzed. Results. There was significant difference in the overall survival rate between lobectomy and pneumonectomy groups (P=0.044). For patients with stage II SCLC, the overall survival rate after pneumonectomy was significantly better than after lobectomy (P=0.028). No significant difference in overall survival rate was found between the two surgical groups in patients with stage III SCLC (P=0.933). The local recurrence rate in lobectomy group was significant higher that in pneumonectomy group (P=0.0017). Conclusions. SCLC was responsive to surgical therapy. When surgeons have to select an appropriate method of operation for patients with SCLC during surgery, pneumonectomy may be the right choice for these patients. Pneumonectomy can result in significantly better local control and higher survival rate compare with lobectomy.
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Luo, Jizhuang, Chunyu Ji, Alessio Campisi, Tangbing Chen, Walter Weder, and Wentao Fang. "Surgical Outcomes of Video-Assisted versus Open Pneumonectomy for Lung Cancer: A Real-World Study." Cancers 14, no. 22 (November 19, 2022): 5683. http://dx.doi.org/10.3390/cancers14225683.

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Background: The safety, feasibility and potential benefits of Video-assisted thoracoscopic surgery (VATS) pneumonectomy remain to be investigated. Methods: Patients receiving VATS or Open pneumonectomy during the study period were included to compare surgical outcomes. Propensity-score matched (PSM) analysis was performed to eliminate potential biases. Results: From 2013 to 2020, 583 consecutive patients receiving either VATS (105, 18%) or Open (478, 82%) pneumonectomy were included. Conversion from VATS to open was found in 20 patients (19.0%). The conversion patients had similar rates of major complications and perioperative mortality compared with the Open group. After PSM, 203 patients were included. No significant differences were observed in major complications and perioperative mortality between the two groups. For patients with stage pT2 tumors, the major complication rate in the VATS group was significantly lower than in the Open group (7.6% vs. 20.6%, p = 0.042). Compared with left pneumonectomy, the incidence of bronchopleural fistula (BPF) was significantly higher in right pneumonectomy for both VATS (0 vs. 16.7%, p = 0.005) and Open (0.7% vs. 6.5%, p = 0.002) approaches. Conclusions: Perioperative results of VATS pneumonectomy are non-inferior to those of the Open approach. Conversion to open surgery does not compromise perioperative outcomes. Patients with lower pT stage tumors who need pneumonectomy may benefit from VATS.
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Sakakura, Noriaki, Tetsuya Mizuno, Hiroaki Kuroda, and Yukinori Sakao. "Primary pneumonectomy, pneumonectomy after induction therapy, and salvage pneumonectomy: a comparison of surgical and prognostic outcomes." Journal of Thoracic Disease 12, no. 5 (May 2020): 2672–82. http://dx.doi.org/10.21037/jtd.2020.03.19.

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30

TAMURA, Kohichi, Shinzo TAKAMORI, Hiroharu MIFUNE, Akihiro HAYASHI, and Kazuo SHIROUZU. "Changes in atrial natriuretic peptide concentration and expression of its receptors after pneumonectomy in the rat." Clinical Science 99, no. 4 (September 7, 2000): 343–48. http://dx.doi.org/10.1042/cs0990343.

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Atrial natriuretic peptide (ANP) is a cardiac hormone which affects endothelial cell function through a receptor-mediated process. Pneumonectomy is a common thoracic surgical procedure that can cause pulmonary oedema in the remaining lung. Few reports have investigated the aetiology of this complication. The aim of this study was to determine the changes in ANP concentration and expression of its receptors following pneumonectomy as a possible aetiology for postpneumonectomy pulmonary oedema (PPE). We compared plasma ANP concentrations, cGMP concentrations, and natriuretic peptide receptor (NPR)-A mRNA and NPR-C mRNA expression in rat lung 3 h after pneumonectomy (n = 5) or a sham operation (n = 5). The ANP concentrations in plasma and lung tissue in the pneumonectomy group were significantly higher than in the control group (749.5 versus 202.7 pgċml-1, P < 0.01; 33.1 versus 6.8 ngċg-1 wet tissue, P < 0.01 respectively). The level of ANP mRNA expression in the pneumonectomy group was significantly higher than in the control group (1.44 versus 0.41 relative ANP mRNA expression, P < 0.05). The concentration of cGMP and the level of NPR-A mRNA expression were not significantly different between the pneumonectomy and control groups. The level of NPR-C mRNA expression in the pneumonectomy group was significantly higher than in the control group (4.17 versus 2.19 relative NPR-C mRNA expression, P < 0.01). These findings suggest that changes in pulmonary ANP and NPR-C expression may contribute to the development of PPE in the remaining lung in the acute phase following pneumonectomy.
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Rego, Erica, Ahmed Abdelmeguid, Yuqi (Kevin) Wang, and Karuna Dewan. "An Uncommon Cause of Dysphagia: Postpneumonectomy Syndrome." Case Reports in Otolaryngology 2021 (March 8, 2021): 1–4. http://dx.doi.org/10.1155/2021/6658690.

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Objective. Dysphagia after pneumonectomy is uncommon but concerning. The purpose of this paper is to present a case of dysphonia secondary to postpneumonectomy syndrome. Case Report. A 66-year-old female with stage IIIa adenocarcinoma of the lung was treated with a left pneumonectomy. Three years later, she presented with severe dysphagia, dyspnea, and dysphonia. Esophagram demonstrated severely deviated esophagus to the left of midline, attributed to prior left-sided pneumonectomy, without clear evidence of any external compression. Chest CT scan showed associated leftward mediastinal shift. This patient was treated with voice therapy and an exclusion diet, as the patient elected not to have surgery. Conclusion. This is the first reported case of dysphonia accompanying severe dysphagia following left pneumonectomy. While postpneumonectomy syndrome is rare, a high degree of clinical suspicion is recommended when treating patients with history of pneumonectomy.
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32

Joo, J. B., James R. Debord, Charles E. Montgomery, James R. Munns, J. Stephen Marshall, J. Kevin Paulsen, Richard C. Anderson, Lynn E. Meyer, and Norman C. Estes. "Perioperative Factors as Predictors of Operative Mortality and Morbidity in Pneumonectomy." American Surgeon 67, no. 4 (April 2001): 318–22. http://dx.doi.org/10.1177/000313480106700404.

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Pneumonectomy for lung cancer is associated with significant morbidity and mortality. Risk factors for the morbidity and mortality have been reported, but consistent conclusive data are undetermined. Current accepted 30-day mortality rates for pneumonectomy range from 7 to 11 per cent. The objective of this study is to determine whether various perioperative factors can serve as predictors of morbidity and mortality in pneumonectomy patients and to review outcome data on patients undergoing pneumonectomy for lung cancer. A total of 105 patients undergoing pneumonectomy for lung cancer from 1988 through 1998 are studied in a retrospective chart review. The main outcome measure is the 30-day operative mortality and morbidity. Complications occurring in 10 per cent or more of the patients included atrial fibrillation (33.3%), respiratory failure (23.8%), pneumonia (21.9%), and bronchopleural fistula (12.4%). The 30-day mortality rate was 10.5 per cent (11 deaths). By Fisher's exact test for Chi-square only three statistically significant mortality factors were identified: respiratory failure ( P < 0.021), sepsis ( P < 0.008), and male sex ( P < 0.031); respiratory failure, sepsis, and sex were predictors of death. Significant correlation could not be made to predict postoperative morbidity. Overall long-term clinical outcome for pneumonectomy as lung cancer treatment was poor. Clinical judgment remains an essential factor when considering pneumonectomy as an option for lung cancer treatment.
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Vasyukov, M. N. "Computed tomography diagnostics of mediastinal hernias after pneumonectomy." Grekov's Bulletin of Surgery 180, no. 6 (May 25, 2022): 19–28. http://dx.doi.org/10.24884/0042-4625-2021-180-6-19-28.

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The formation of mediastinal hernias after pneumonectomy may be associated with the development of complications from the remaining lung. The lack of information about the patterns of their development, morphometric characteristics, and dynamics in the postoperative period indicates the urgency of the problem.The OBJECTIVE was to reveal the topographic and anatomical patterns of the formation of mediastinal hernias after pneumonectomy, to give anatomometric characteristics at various times after the operation.METHODS AND MATERIALS. Computed tomography of the chest of 53 patients (50 men and 3 women) aged 39 to 75 years before and after pneumonectomy (26 on the left, 27 on the right) were examined. Computed tomography was performed on the 10–12th day, 6 and 12 months after surgery. The transverse size of anterior and posterior mediastinal hernias after left- and right-sided pneumonectomies, their dynamics, and density of lung tissue in the hernial protrusion area were studied. 3D was performed – modeling of the remaining lung. RESULTS. Hernial protrusions were visualized in patients with atelectasis of the lung part before surgery. 10 days after left pneumonectomy, anterior and posterior mediastinal hernias were visualized in 80.8 % of patients. One year after left surgery, anterior hernias were observed in 91.7 % of patients, they increased in size and the average size was (57.3±5.2) mm at the ThV–VI level. Posterior mediastinal hernias 12 months after left pneumonectomy were found in 80.5 % of patients, the average size was (34.9±5.2) mm at the ThVIII level. After right pneumonectomy in the early postoperative period, anterior mediastinal hernias occurred in 70.3 % of patients, a year later-in 88.2 %, the average size was (41.0±7.6) mm at the ThV level. The average transverse sizes of anterior mediastinal hernias 12 months after left and right pneumonectomies did not differ significantly (P=0.950). Posterior mediastinal hernias after right surgery were found in 20.0 % of patients, the largest size was determined at the ThIX level, with an average of (12.7±5.8) mm. After pneumonectomy, bullous changes occured in the lung tissue of mediastinal hernias.CONCLUSION. Anterior mediastinal hernias are equally common after left and right pneumonectomy, while the size of the hernias did not differ significantly. Posterior mediastinal hernias after left pneumonectomy occurs in 88.2 % of patients, after right pneumonectomy – in 20 % of cases.
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34

Duranti, Leonardo, Alessandro Pardolesi, Luca Bertolaccini, Luca Tavecchio, Paolo Scanagatta, Luigi Rolli, and Ugo Pastorino. "Extra-pleural pneumonectomy." Journal of Thoracic Disease 11, no. 3 (March 2019): 1022–30. http://dx.doi.org/10.21037/jtd.2019.02.61.

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35

Kostic, Marko, and Jean-Marc Baste. "Pneumonectomy for empyema." Shanghai Chest 5 (April 2021): 20. http://dx.doi.org/10.21037/shc-20-62.

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36

Shelley, B., and J. Kinsella. "Outcome after pneumonectomy." British Journal of Anaesthesia 106, no. 6 (June 2011): 907. http://dx.doi.org/10.1093/bja/aer133.

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37

Wagner, James W., Farouck N. Obeid, Riyad C. Karmy-Jones, Gregory D. Casey, Victor J. Sorensen, and H. Mathilda Horst. "Trauma Pneumonectomy Revisited." Journal of Trauma: Injury, Infection, and Critical Care 40, no. 4 (April 1996): 590–94. http://dx.doi.org/10.1097/00005373-199604000-00012.

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38

Ashour, M. "Pneumonectomy for tuberculosis." European Journal of Cardio-Thoracic Surgery 12, no. 2 (August 1997): 209–13. http://dx.doi.org/10.1016/s1010-7940(97)00155-3.

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39

da Silva, Paulo Sérgio Lucas, Renato de Oliveira, Nikkei Tamura, and Henrique Monteiro Neto. "Right Pneumonectomy Syndrome." Pediatric Emergency Care 26, no. 7 (July 2010): 499–502. http://dx.doi.org/10.1097/pec.0b013e3181e5bfb3.

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40

Conlan, A. Alan. "Pneumonectomy for infection." Annals of Thoracic Surgery 60, no. 2 (August 1995): 488–89. http://dx.doi.org/10.1016/s0003-4975(95)81058-7.

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41

Hackett, S., R. Jones, and R. Kapila. "Anaesthesia for pneumonectomy." BJA Education 19, no. 9 (September 2019): 297–304. http://dx.doi.org/10.1016/j.bjae.2019.04.004.

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42

Gozzetti, Giuseppe, Mario Mastrorilli, Romano B. Bragaglia, Giulio Cipolla D'Abruzzo, Anna Romualdi, Silvia Villani, Gian Luca Liberatore, and Renato Spolaore. "The “Kergin pneumonectomy”." World Journal of Surgery 14, no. 5 (September 1990): 624–27. http://dx.doi.org/10.1007/bf01658808.

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43

Blyth, D. "Pneumonectomy in children." European Journal of Cardio-Thoracic Surgery 22, no. 4 (October 2002): 587–94. http://dx.doi.org/10.1016/s1010-7940(02)00404-9.

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Hannan, L. M., S. A. Joosten, D. P. Steinfort, P. Antippa, and L. B. Irving. "The pneumonectomy syndrome." Thorax 67, no. 7 (December 5, 2011): 656–57. http://dx.doi.org/10.1136/thoraxjnl-2011-201078.

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45

Allen, Aaron M., Steven J. Mentzer, Beow Y. Yeap, Ricardo Soto, Elizabeth H. Baldini, Michael S. Rabin, David J. Sugarbaker, and Raphael Bueno. "Pneumonectomy after chemoradiation." Cancer 112, no. 5 (2008): 1106–13. http://dx.doi.org/10.1002/cncr.23283.

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WONG, P., and P. GOLDSTRAW. "Post-pneumonectomy empyema." European Journal of Cardio-Thoracic Surgery 8, no. 7 (1994): 345–50. http://dx.doi.org/10.1016/1010-7940(94)90027-2.

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Nwogu, Chumy E., Michal Glinianski, and Todd L. Demmy. "Minimally Invasive Pneumonectomy." Annals of Thoracic Surgery 82, no. 1 (July 2006): e3-e4. http://dx.doi.org/10.1016/j.athoracsur.2006.04.054.

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48

DeAnda, Abe, John L. Cahill, Daniel Bernstein, Vaughn A. Starnes, and Bruce A. Reitz. "Elective transplant pneumonectomy." Journal of Pediatric Surgery 33, no. 4 (April 1998): 655–56. http://dx.doi.org/10.1016/s0022-3468(98)90339-6.

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49

Smeenk, FW, SP Twisk, E. Berreklouw, HC Gooszen, and PE Postmus. "Dyspnoea after pneumonectomy." European Respiratory Journal 4, no. 2 (February 1, 1991): 243–45. http://dx.doi.org/10.1183/09031936.93.04020243.

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Abstract:
We report the case of a 61 yr old male, who developed a severe right-to-left shunt through a patent foramen ovale, in the absence of elevated right-sided heart pressures, two months after a left-sided pneumonectomy. This is considered to be a rare complication after pneumonectomy. However, taking into account the approximately 20% incidence of patent foramen ovale in the general population, we suggest that right-to-left shunting through an unsuspected foramen ovale or atrial septum defect should always be considered as a possible cause of otherwise unexplained hypoxaemia.
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Sharma, Nisha, Ankita Chandel, and Manjit Singh Kanwar. "Laparoscopic cholecystectomy in a patient with pneumonectomy." International Journal of Research in Medical Sciences 8, no. 4 (March 26, 2020): 1582. http://dx.doi.org/10.18203/2320-6012.ijrms20201365.

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Post pneumonectomy patients pose a challenge to the anaesthetist owing to the altered respiratory mechanics and decreased respiratory reserve. Performing laparoscopic surgery in such patients further deteriorates the already compromised lung functions. Authors report a case of laparoscopic cholecystectomy performed in post pneumonectomy patient. A clear understanding of respiratory mechanics and post pneumonectomy physiological changes helped us to administer a safe anaesthesia and safe perioperative outcome.
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