Relevant bibliographies by topics / Pneumonectomy

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers

Academic literature on the topic 'Pneumonectomy'

Author: Grafiati
Published: 4 June 2021
Last updated: 20 February 2023

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Journal articles on the topic "Pneumonectomy"

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Lee, Kenneth Robert. "Pneumonectomy." Chest 134, no. 6 (December 2008): 1347. http://dx.doi.org/10.1378/chest.08-1500.

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Zhao, Jasmine, Alexandra Nguyen, Li Ding, Elizabeth A. David, Scott M. Atay, Sean C. Wightman, P. Michael McFadden, and Anthony W. Kim. "Trends in pneumonectomy for treatment of small-cell lung cancer." Asian Cardiovascular and Thoracic Annals 28, no. 9 (September 2, 2020): 583–91. http://dx.doi.org/10.1177/0218492320955054.

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Background According to practice guidelines, patients with clinical stage T1–2 node-negative small-cell lung cancer are candidates for surgical resection. However, the role of pneumonectomy in small-cell lung cancer patients is not well understood. The objective of this study was to assess the extent to which pneumonectomy is used and to evaluate the survival implications for small-cell lung cancer patients who underwent pneumonectomy. Methods A total of 106 small-cell lung cancer patients who underwent pneumonectomy between 2006 and 2016 and met the study criteria were identified in the National Cancer Database. Demographics and treatment regimens are described, and overall survival was assessed using Kaplan-Meier and log-rank tests. Results The most common treatment was surgery with adjuvant chemotherapy, followed by surgery only and surgery with neoadjuvant therapy. The 5-year overall survival for the entire cohort after pneumonectomy was 23%. In subgroup analysis, the 5-year overall survival was 30% for guideline-concordant clinical stage I patients and 28% for clinical stage II/III patients who underwent pneumonectomy. There was no statistical difference in survival according to pathologic N disease. Patients with a right-sided pneumonectomy had higher mortality than patients with a left-sided pneumonectomy. Conclusions This study suggests a role for pneumonectomy in clinical stage I and potentially some clinical stage II and III small-cell lung cancer patients. Right-sided pneumonectomy is associated with higher mortality and should be approached with caution. Despite declining trends over the past decades, pneumonectomy is still an effective treatment that is able to achieve acceptable survival outcomes.
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Kim, Noheul, and Ronny Priefer. "Drug Regimen for Patients after a Pneumonectomy." Journal of Respiration 1, no. 2 (April 13, 2021): 114–34. http://dx.doi.org/10.3390/jor1020013.

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Pneumonectomy is an entire lung removal and is indicated for both malignant and benign diseases. Due to its invasiveness and postoperative complications, pneumonectomy is still associated with high mortality and morbidity. Appropriate postoperative management is crucial in pneumonectomy patients to improve quality of life and overall survival rates. Diverse drug regimens are under development to be used in adjuvant chemotherapy or to improve respiratory health after a pneumonectomy. The most common causes for a pneumonectomy are non-small cell lung cancer, malignant pleural mesothelioma, and tuberculosis; thus, an appropriate drug regimen is necessary. The uncommon incidence of pneumonectomy cases remains the major obstacle in studies of postoperative drug regimens. As the majority of current studies include post-lobectomy and post-segmentectomy patients, it is highly recommended that further research of postoperative drug regimens be focused on post-pneumonectomy patients.
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Galetta, Domenico, and Lorenzo Spaggiari. "Robotic pneumonectomy." Shanghai Chest 5 (January 2021): 6. http://dx.doi.org/10.21037/shc.2020.04.01.

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Avella Patino, Diego, and Mark K. Ferguson. "Right pneumonectomy." Shanghai Chest 1 (2017): 10. http://dx.doi.org/10.21037/shc.2017.05.08.

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Galetta, Domenico, and Lorenzo Spaggiari. "Extrapleural pneumonectomy." Shanghai Chest 1 (2017): 32. http://dx.doi.org/10.21037/shc.2017.08.13.

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Thirugnanam, Agasthian. "Completion pneumonectomy." ASVIDE 3 (December 2016): 518. http://dx.doi.org/10.21037/asvide.2016.518.

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Royo-Crespo, Iñigo, Arthur Vieira, and Paula A. Ugalde. "Right pneumonectomy." ASVIDE 5 (March 2018): 179. http://dx.doi.org/10.21037/asvide.2018.179.

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Aigner, Clemens, Gyoergy Lang, and Walter Klepetko. "Sleeve Pneumonectomy." Seminars in Thoracic and Cardiovascular Surgery 18, no. 2 (June 2006): 109–13. http://dx.doi.org/10.1053/j.semtcvs.2006.05.005.

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Qadri, Syed S. A., Alex Cale, Mahmoud Loubani, Mubarak Chaudhry, and Michael Cowen. "Extrapleural Pneumonectomy." PLEURA 2 (July 21, 2015): 237399751559521. http://dx.doi.org/10.1177/2373997515595219.

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Dissertations / Theses on the topic "Pneumonectomy"

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Simões, Edson Azevedo. "Estudo comparativo entre sutura mecânica e manual em brônquio após pneumonectomia esquerda em cães (Canis familiaris): uma avaliação anatomo-patológica, paramétrica, radiológica e broncoscópica." Universidade de São Paulo, 2003. http://www.teses.usp.br/teses/disponiveis/10/10137/tde-07082007-114644/.

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Em cães, os estudos experimentais comparativos dos diferentes tipos de sutura para a síntese do brônquio principal são escassos, quando não ausentes nesta espécie. Além disso, existem possíveis complicações decorrentes da má cicatrização do brônquio. O objetivo deste estudo foi realizar um estudo experimental comparando-se sob o ponto de vista anatomo-patológico, paramétrico, radiológico e broncoscópico as suturas manual e mecânica em brônquio principal após pneumonectomia esquerda em cães. Foram utilizados 18 cães, sadios, machos e fêmeas, adultos, sem raça definida, pesando entre 9 e 27,5 kg. Os cães foram submetidos à intubação seletiva e toracotomia esquerda no 5º espaço intercostal, onde foi feita a pneumonectomia. Foram separados em 2 grupos de 9 cães, de acordo com o tipo de sutura empregada: Grupo A - sutura manual do coto brônquico principal esquerdo com pontos separados \"em 8\" com fio polipropileno 5-0; Grupo B - sutura mecânica do coto brônquico principal esquerdo com grampeador mecânico modelo TL-30 com grampos dispostos em fileira dupla. Cada grupo foi subdividido em 3 subgrupos de 3 animais, sendo estabelecido estudo temporal aos 7, 15 e 36 dias de pós-operatório, onde foi realizado a avaliação anatomo-patológica da cicatrização das suturas manual e mecânica, bem como, a avaliação paramétrica (antes da indução da anestesia, imediatamente após o final do ato cirúrgico, 48 horas, 7, 15 e 36 dias após o procedimento cirúrgico), avaliação radiológica ( 24 horas antes e com 7, 15 e 36 dias após o procedimento cirúrgico) e avaliação broncoscópica (após indução anestésica e com 7, 15 e 36 dias após o procedimento cirúrgico), consideradas importantes para avaliar possíveis complicações decorrentes deste tipo de procedimento cirúrgico. Estas avaliações foram realizadas de acordo com o estudo temporal nos diferentes subgrupos. A avaliação paramétrica foi realizada através da mensuração da temperatura, hematócrito, hemoglobina, freqüências cardíaca e respiratória. Na avaliação histopatológica foram avaliados qualitativamente e semi-quantitativamente a intensidade da inflamação, fibrose, vasos neoformados e a presença ou não de tecido de granulação, granuloma tipo corpo estranho e necrose. Os resultados encontrados foram analisados estatisticamente. Apesar das alterações dos índices paramétricos, todos os cães apresentaram evolução pós-operatória satisfatória. Com relação à análise histopatológica, ocorreu a formação de granuloma tipo corpo estranho no coto brônquico esquerdo em 88,9% dos cães submetidos à sutura manual e em nenhum dos cães submetidos à sutura mecânica. Houve ainda, diferença estatística significativa nos cães dos Grupos A e B em relação à intensidade da inflamação, sendo de maior intensidade nos cães submetidos à sutura manual. Os resultados obtidos mostraram não haver diferença estatística significativa nas avaliações radiográficas e broncoscópicas entre os Grupos A e B. Não foram observadas intercorrências no trans e pós-operatório. Concluiu-se que os 2 tipos de sutura promoveram cicatrização adequada do coto brônquico principal esquerdo, embora tenha ocorrido maior intensidade de inflamação e maior ocorrência de granuloma tipo corpo estranho nos cães submetidos à sutura manual, permitindo evolução paramétrica, radiológica, broncoscópica pós-operatória satisfatória e sem diferença nos cães dos Grupos A e B.
In dogs, comparative experimental studies of the different types of sutures for the synthesis of the main bronchus are scarce, when not all available in this species. Furthermore, there are possible complications due to the poor healing of the bronchus. The objective of this study was to perform an experimental study to be compared under the pathological-anatomic, parametric, radiological and bronchoscopic point of views, the manual and mechanical sutures in the main bronchus after left pneumonectomy in dogs. Eighteen adult mongrel, healthy dogs, both male and female, were utilized weighing from 9 to 27.5 kg. The dogs were submitted to a selective intubation and left thorax incision in the 5 th intercostal space where a pneumonectomy was performed. Were separated into 2 groups of 9 dogs according to the type of suture employed: Group A - a manual suture of the main left bronchial stump with separate stitches \"in 8\" with polypropylene 5-O; Group B - a mechanical suture of main left bronchial stump with a mechanical stapler, model TL-30 arranged in a double file. Each group was subdivided into 3 subgroups of 3 animals and a temporal postoperative study was established at 7, 15 and 36 days where an pathological-anatomic evaluation was made on the healing of the manual and mechanical sutures as well as a parametric evaluation (before the induction of anesthesia, immediately after the final surgical act, 48 hours, 7, 15 and 36 days after the surgical procedure), radiological evaluation (24 hours before and with 7, 15 and 36 days after the surgical procedure), and bronchoscopic evaluation (after the induction of anesthesia and with, 7, 15 and 36 days after the surgical procedure), considered important to evaluate possible complications due to this type of surgical procedure. These evaluations were made according to the temporal study in the subgroups. The parametric evaluation was made through the mensuration of temperature, hematocrit, hemoglobin, heart and respiratory rate. During the histopathological evaluation, the intensity of inflammation, fibrosis, neoformed vessels, and the presence or absence of granulation tissue, foreign body reaction and necrosis were evaluated qualitatively and semi-quantitatively. The results found were analyzed statistically. Although the difference observed in the parametric evaluations, all the dogs showed good recovery postoperative. Regarding the histopathologic analysis, foreign body reaction occured in the left bronchial stump in 88,9% of the dogs submitted to a manual suture and in none of the dogs submitted to a mechanical suture. There is still, significant statistical difference in the dogs in Groups A and B in relation to the intensity of the inflammation, the greatest intensity being in the dogs submitted to the manual suture. The results obtained showed that there was no significant statistical difference in the radiographic and bronchoscopic evaluations between Groups A and B. No intercurrences were observed in the trans and postoperative period. It is concluded that both types of sutures brought an adequate healing of the main left bronchial stump, although there was a greater intensity of inflammation and a greater occurence of foreign body reaction in the dogs submitted to the manual suture, permitting satisfactory parametric, radiological and bronchoscopic postoperative evolution and there is no difference in all of the dogs in Groups A and B.
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McLean, Jocelyn Margaret. "Recovery following pneumonectomy: patients initial 2 year experience." University of Sydney. Clinical, 2003. http://hdl.handle.net/2123/563.

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Little is known about the recovery of patients after pneumonectomy and the impact of the surgery on the lifestyle of young, employed, ex-smokers and their families. This study was conducted to address this knowledge deficit, and gather information that would help health professionals to be able to assist people facing pneumonectomy. A qualitative study using van Manens methodological approach to interpretive phenomenology was chosen, in order to capture a full and rich understanding and meaning of the phenomenon that patients live. The names, age, operation, histological cell type, stage of disease, and disease free status of potential participants were obtained from a Lung Cancer Surgical Database after obtaining ethical approval for the study. Nine participants (three females and six males) met the inclusion criteria and gave informed consent for the study. Data collection comprised of open-ended interviews that were audiotaped, then transcribed verbatim into hard data. Data interpretation was based on the selective reading approach of van Manen from which six thematic statements arose. These are living the discomforts of treatment and recovery, discovering new limitations on myself; functional and emotional, my reliance on support, my financial security is threatened, my survival is at threat, and I wish I had known more. The study found that each participant had a unique experience of recovery and consequently the degree of recovery attained varied between participants. They all had a very strong desire to survive lung cancer and considered the risks of major surgery and loosing a lung to be insignificant compared to the certainty of loosing their life if they did not undergo surgery. This study provided a glimpse of what it was like for a group of patients to live the experience of life after a pneumonectomy and it provides a basis from which nurses can explore further the experiences of patients who are subjected to lung cancer surgery.
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McLean, Jocelyn. "Recovery following pneumonectomy patients initial 2 year experience /." Connect to full text, 2002. http://hdl.handle.net/2123/563.

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Thesis (M.N. (Res.))--University of Sydney, 2003.
Title from title screen (viewed Apr. 28, 2008). Submitted in fulfilment of the requirements for the degree of Master of Nursing (Research) to the School of Clinical Nursing, Faculty of Nursing. Degree awarded 2003; thesis submitted 2002. Includes bibliography. Also available in print form.
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McLean, Jocelyn Margaret. "Recovery following pneumonectomy: patients initial 2 year experience." Thesis, The University of Sydney, 2002. http://hdl.handle.net/2123/563.

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Little is known about the recovery of patients after pneumonectomy and the impact of the surgery on the lifestyle of young, employed, ex-smokers and their families. This study was conducted to address this knowledge deficit, and gather information that would help health professionals to be able to assist people facing pneumonectomy. A qualitative study using van Manens methodological approach to interpretive phenomenology was chosen, in order to capture a full and rich understanding and meaning of the phenomenon that patients live. The names, age, operation, histological cell type, stage of disease, and disease free status of potential participants were obtained from a Lung Cancer Surgical Database after obtaining ethical approval for the study. Nine participants (three females and six males) met the inclusion criteria and gave informed consent for the study. Data collection comprised of open-ended interviews that were audiotaped, then transcribed verbatim into hard data. Data interpretation was based on the selective reading approach of van Manen from which six thematic statements arose. These are living the discomforts of treatment and recovery, discovering new limitations on myself; functional and emotional, my reliance on support, my financial security is threatened, my survival is at threat, and I wish I had known more. The study found that each participant had a unique experience of recovery and consequently the degree of recovery attained varied between participants. They all had a very strong desire to survive lung cancer and considered the risks of major surgery and loosing a lung to be insignificant compared to the certainty of loosing their life if they did not undergo surgery. This study provided a glimpse of what it was like for a group of patients to live the experience of life after a pneumonectomy and it provides a basis from which nurses can explore further the experiences of patients who are subjected to lung cancer surgery.
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Simões, Edson Azevedo. "Viabilidade da pnemonectomia direita em cães (Canis falimilaris): uma avaliação paramétrica, hemogasométrica, ecocardiográfica, radiográfica, broncoscópica e da mecânica respiratória." Universidade de São Paulo, 2008. http://www.teses.usp.br/teses/disponiveis/10/10137/tde-14042008-132446/.

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Em cães, a comprovação da real viabilidade da pneumonectomia direita, bem como, o estudo das complicações resultantes deste procedimento cirúrgico, tornam-se importantes diante da pequena quantidade de estudos na literatura específicos sobre pneumonectomia nesta espécie. O objetivo deste trabalho foi realizar um estudo experimental para avaliar a viabilidade da pneumonectomia direita em cães, através da avaliação paramétrica, hemogasométrica, ecocardiográfica, radiográfica, broncoscópica e da mecânica respiratória. Foram utilizados 10 cães, sadios, machos e fêmeas, adultos, sem raça definida, pesando entre 13 e 32 kg. Todos os cães foram submetidos à intubação seletiva e toracotomia direita no 5º espaço intercostal, onde foi realizada a pneumonectomia. Foi realizado estudo temporal aos sete, 30 e 60 dias de pós-operatório, onde foi feita avaliação ecocardiográfica, radiográfica e broncoscópica. A avaliação paramétrica e hemogasométrica foi realizada antes da indução anestésica, uma hora após extubação, 48 horas, sete, 30 e 60 dias após o procedimento cirúrgico. A avaliação da mecânica respiratória foi realizada antes da indução anestésica, durante a cirurgia, 48 horas, sete, 30 e 60 dias após o procedimento cirúrgico. Estas avaliações foram consideradas importantes para determinar as possíveis complicações relacionadas com a técnica anestésica, cirúrgica, assim como, as complicações resultantes deste procedimento cirúrgico. Os resultados encontrados foram analisados estatisticamente. Apesar das alterações dos índices paramétricos, hemogasométricos e da mecânica respiratória, todos os cães apresentaram compensação das trocas gasosas após retirada do pulmão direito. Em relação a avaliação da mecânica respiratória, os volumes pulmonares não se modificam de maneira acentuada. Ocorreu aumento das pressões de pico e resistência das vias aéreas devido ao emprego da sonda de duplo lúmen e ressecção pulmonar. Não houve diferença significativamente estatística nos níveis da pressão sistólica e média no tronco pulmonar. Entretanto, alguns cães apresentaram hipertensão pulmonar leve e transitória, sendo que o período de maior incidência foi aos 30 dias de pós-operatório. A fração de ejeção do ventrículo direito manteve-se normal durante o estudo. No entanto, nos mesmos cães que apresentaram hipertensão pulmonar, houve diminuição significativa da fração de ejeção do ventrículo direito aos 60 dias de pós-operatório. Na avaliação radiográfica, observamos que a expansão do pulmão remanescente causou deslocamento do coração e pulmão para hemitórax direito. Nas imagens broncoscópicas pós-operatórias não foram observadas quaisquer sinais de infecção, deiscência, fístula e estenose da sutura em coto brônquico. Concluiu-se que a realização da pneumonectomia direita é plenamente viável no cão, permitindo evolução paramétrica, hemogasométrica, ecocardiográfica, radiográfica, broncoscópica e da mecânica respiratória satisfatória em todos os cães.
In dogs, the evidence of the viability of right pneumonectomy, as well as the study of the complications resulting from surgical procedure, are very important against the small quantity of specific studies on pneumonectomy in this species. The objective of this project was carrying out an experimental study to evaluate the viability of right pneumonectomy in dogs, through parametric, hemogasometric, echocardiographic, radiographic, broncoscopic and mechanical respiratory evaluation. Ten adult mongrel, healthy dogs, both male and female were utilited weighing from 13 to 32 kg. The dogs were submitted to selective intubation and right thoracotomy at the 5th intercostal space, where the pneumonectomy was performed. A temporal study was made in 7, 30 and 60 days after the surgery, where echocardiographic, radiografic and bronchoscopic evaluation were done. The parametric and hemogasometric evaluations was made before anesthetic induction, one hour after extubation, in 48 hour, seven, 30 and 60 days after the surgical procedure. The mechanical respiratory evaluation was before anesthetic induction, during surgery, 48 hour, seven, 30 and 60 days after the surgical procedure. These evaluations were considered important to determine the probable complications connected to the anesthetic, surgical techniques, as well as the resulting complications from these procedures. The results were analyzed statistically. Besides the alterations of the parametric, hemogasometric and mechanical respiratory rates, all the dogs presented compensations on the gaseous exchanges after removing right lung. Regarding the mechanical respiratory evaluation, the pulmonary volume has not changed accentually. There was an increase of the peak pressures and resistance of the respiratory tract due to the use of a double lumen probe and lung ressection. There wasn\'t any significant statistically difference on the levels of systolic and average pressure on the pulmonary trunk. However, some dogs showed light and transitory pulmonary hypertension, and the highest occurrence period happened 30 days after surgery. The fraction of ejection of the right ventricle remained normal during the study. However, at the same dogs who presented pulmonary hypertension, there was a significant decrease of the fraction of the right ventricle 60 days after surgery. On the radiographic evaluation, we have observed that the expansion of the remaining lung caused heart and lung displacement to the right hemithorax. Any signs of infection, dehiscence, fistula or suture stenosis in the main right bronchial stump were observed on the post-operative bronchoscopic images. It follows that the right pneumonectomy is completely feasible the dogs, allowing a parametric, hemogasometric, echocardiographic, radiographic, bronchoscopic and mechanical respiratory satisfactory evaluation in all the dogs.
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Yasa, Joe. "Insulin-like Growth Factor-1 in post-pneumonectomy lung regeneration." Thesis, Yasa, Joe (2019) Insulin-like Growth Factor-1 in post-pneumonectomy lung regeneration. PhD thesis, Murdoch University, 2019. https://researchrepository.murdoch.edu.au/id/eprint/50128/.

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Insulin Growth Factor-1 (IGF-1), is a key and highly regulated molecule which stimulates somatic growth. The level of serum IGF-1 in humans peaks at adolescence and declines with age. IGF-1 expression is also critical for embryonic lung development and is expressed in the regenerating lung of young animals following pneumonectomy (PNX), the surgical removal of a lung. The murine left-lung PNX model was used to investigate the hypothesis that IGF-1 enhances the regenerative capacity of the lung. The potential interactions of IGF-1 and the transcription factors early growth response protein 1 (EGR-1) and hypoxia-inducible factor-1α (HIF-1α) in post-PNX lung growth was also investigated. I demonstrated that following left-lung PNX in young mice (aged 2-3 months) pre-operative total lung volume and tissue volume is restored by day 21 post-surgery. IGF-1 mRNA and protein levels were significantly induced in the remaining lung, with a transient but significant increase in IGF-1+, pIGF-1R+ and pERK-1/2+ lung cells, at day three post-PNX compared to SHAM treated mice. I then showed that intraperitoneal administration of IGF-1 following PNX significantly increases the rate of lung volume and tissue volume recovery and the level of lung cell proliferation, when assessed at day seven post-surgery. In contrast, blocking IGF-1 activity by pharmacological inhibition of IGF-1R signalling, significantly attenuated post-PNX lung growth. In young mice receiving continuous subcutaneous infusion of IGF-1 following PNX, the rate of lung volume recovery to pre-operative levels was similar to age-matched PBS-treated PNX mice. However, lung sections assessed at day 23 post-surgery revealed that IGF-1-treated mice lungs had significantly higher numbers of IGF-1+, pIGF-1R+, pERK-1/2+ lung cells, proliferating SpC+ type two alveolar epithelial cells and number of alveoli per unit area, suggesting that IGF-1 treatment was associated with additional regenerative activity. In old PNX mice (aged 22-24 months), there was a significant increase in aerated lung volume following continuous subcutaneous administration of IGF-1, compared to age-matched PBS-treated controls. However, unlike young mice, there was no evidence of restoration of pre-operative total lung volume or tissue volume by day 21 post-surgery in either treatment groups. Additionally, lung sections assessed at day 23 post-surgery revealed no differences between IGF-1 and PBS treated lungs in the numbers of IGF-1+, pIGF-1R+ and pERK-1/2+ lung cells, or proliferating SpC+ alveolar type two epithelial cells or the number of alveoli per unit area. Finally, I investigated the potential for interactions of IGF-1 and the transcription factors EGR-1 and HIF-1α in post-PNX lung growth. I demonstrated that IGF-1 treatment can induce EGR-1 and HIF-1α protein expression in cultured 3T3 fibroblasts. Furthermore, both EGR-1 and HIF-1α were transiently increased in the parenchyma of the lung at day three post-PNX, coinciding with the peak of IGF-1 expression. Pharmacological inhibition of either EGR-1 or HIF-1α activity significantly reduced the density of CD31+ cells and CD31 protein levels in the lung. Additionally, pharmacological inhibition of HIF-1α activity in the lung following PNX significantly reduced lung cell proliferation at day seven post-surgery. Intraperitoneal administration of IGF-1 was able to restore the level of lung cell proliferation in HIF-1α inhibited PNX lungs to the levels of untreated PNX lungs. These results collectively point to a temporally coordinated involvement IGF-1, EGR-1 and HIF-1α during post-PNX regenerative lung growth, and that additional IGF-1 treatment can enhance such growth following PNX in young mice, but not in aged mice. Furthermore, these studies have identified a potential age-dependent defect in responsiveness to IGF-1 in the lung, which warrants further investigation.
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Irino, Eduardo Toshio. "Avaliação histopatológica do pulmão esquerdo e avaliação eletrocardiográfica em cães (Canis familiaris) submetidos à pneumonectomia direita." Universidade de São Paulo, 2006. http://www.teses.usp.br/teses/disponiveis/10/10137/tde-06032007-160503/.

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A utilização das ressecções pulmonares em cães e gatos, quer sejam por lobectomia ou pneumonectomia, é realizada no intuito de cura ou paliação de processos broncopulmonares sempre que os meios conservadores de tratamento clínico sejam considerados ineficientes. Tendo em vista as significativas modificações que a pneumonectomia acarreta, novos estudos experimentais devem ser feitos para elucidar as vantagens desta intervenção cirúrgica, bem como aplicá-la com a devida segurança. O presente estudo tem como objetivo avaliar as alterações eletrocardiográficas e as alterações histopatológicas no pulmão esquerdo de cães submetidos à pneumonectomia direita. Foram utilizados dez cães, machos ou fêmeas, adultos, sem raça definida e pesando entre dez e trinta quilos. Foram avaliados os parâmetros clínicos do animal diariamente, as alterações em todas as derivações do eletrocardiograma e realizado estudo morfométrico de pulmão esquerdo bem como descrição das principais alterações histopatológicas. Foram descritos tópicos importantes da técnica cirúrgica que colaboram na prevenção de intercorrências trans e pós-operatórias. Todos os animais apresentaram boa evolução pós-operatória. Quanto à análise eletrocardiográfica, apenas um animal apresentou alteração de relevância clínica, sendo a ausência de alterações, a maioria dos casos. Presenciamos um caso de Complexos Ventriculares Prematuros decorrente à parada cardiorrespiratória revertida com sucesso. Verificamos diminuição da amplitude dos Complexos QRS nos primeiros 14 dias, retornado após 60 dias de pós-operatório. Quanto à descrição histopatológica, foram presenciados processos de hiperinsuflação ou alterações parenquimatosas não expressivas. Na análise morfométrica,as artérias intra-acinares indicaram aumento significante da porcentagem de espessura após pneumonectomia direita. As artérias com diâmetro 0-50 µm apresentaram os maiores valores tanto nos períodos pré e pós-operatório, mas a taxa de aumento (%) foi mais evidente nas artérias com diâmetro maior de 100 µm.
The intention of the use of pulmonary resections in dogs and cats, either lobectomy or pneumonectomy, is the cure or palliation of bronchopulmonary processes whenever the conservative clinical treatment means are considered ineffective. Bearing in mind the significant alterations that the pneumonectomy causes, new experimental studies must be done to elucidate the advantages of this surgical intervention, as well as perform it without any risk. The aim of the current study is to evaluate both the eletrocardiographical and the histopathological alterations in the lungs of dogs that were undergone a right pneumonectomy. Ten either male or female adult mongrel dogs weighing between ten and thirty kilos were investigated. The clinical parameters of the animals and the alterations in every eletrocardiogram derivation were evaluated day after day, and a left lung morphometrical study and the description of the main histopathological alterations were made, as well. Important topics of the surgical technique that contribute to prevent the trans and post-operative complications were described. All the animals presented a good post-operative outcome. As for the eletrocardiographical analysis, few of them were of clinical significance and in most cases there were no alterations. We observed a premature ventricular complex case resulted from a cardiorrespiratory arrest that was reverted to successfully. We found out decrease of QRS Complex Amplitude on the 0-14 days, and it returned to normal after sixty post-operative days. As for histopathological description, neither significant hiperinsuflation processes nor parenquimatous alterations were practically observed. In the morphometric analysis, the intra-acinar arteries showed, a significant increase of the thickness percentage after right pneumonectomy. The arteries with diameter 0-50µm presented the most values either period pre or post-operative, but increase rate (%) was more evident in the greater than 100 µm diameter arteries.
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Wong, Jaén Manuel. "Factores de morbilidad y mortalidad a corto y largo plazo en los pacientes sometidos a neumonectomía por cáncer pulmonar en el Hospital Vall d´Hebron entre los años 1993 y 2013." Doctoral thesis, Universitat Autònoma de Barcelona, 2016. http://hdl.handle.net/10803/400017.

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Introducción En el tratamiento quirúrgico del cáncer pulmonar la neumonectomía es un procedimiento esporádico y clásicamente relacionado con mayor morbimortalidad respecto a otro tipo de resecciones. El objetivo de este estudio fue evaluar en este tipo de pacientes, los factores pronósticos relacionados a la morbilidad y mortalidad. Pacientes y Métodos Se desarrolló un estudio retrospectivo, observacional, descriptivo, de 380 pacientes consecutivos, intervenidos en el servicio de cirugía torácica del Hospital Vall d´Hebron entre 1993 y 2013. Se aplicaron pruebas tanto de asociación entre variables, como univariante y multivariante para supervivencia y tiempo libre de enfermedad. Resultados Fueron mayor la prevalencia de pacientes hombres, resecciones derechas y las de tipo convencional, la media de edad fue 61 años. Las complicaciones postoperatorias se presentaron en un 24.2% y la mortalidad peroperatoria y subsecuente fue de 5% y 62% respectivamente. La estirpe más habitual fue Carcinoma Escamoso (56.6 %), y el estadio oncológico IIIA, mayormente en tumores T2, con una media de compromiso N2 de 34.6%. El 55.7% recibió neoadyuvancia y el 57.3% adyuvancia. Se encontraron los siguientes factores de riesgo en función del riesgo de recidiva y muerte: edad superior a 70 años, antecedente de arritmia, neumonectomía derecha, afectación N2, presencia durante el ingreso de distres, infarto al miocardio o necesidad de ventilación mecánica, estadios oncológicos avanzados, y la utilización de adyuvancia. Conclusiones Consideramos que existen factores pre y transoperatorios que influyen tanto en la evolución peroperatoria como en la posterior; impactando directamente en la supervivencia y el tiempo libre de enfermedad y deben ser tomados en cuenta por el equipo médico quirúrgico.
Introduction In the surgical treatment of lung cancer pneumonectomy is a procedure typically sporadic and related to higher morbidity and mortality compared to other resections. The aim of this study was to evaluate in these patients, the prognostic factors related to morbidity and mortality. Patients and Methods A retrospective, observational, descriptive study, with 380 consecutive patients who underwent surgery in the thoracic surgery unit at the Hospital Vall d'Hebron between 1993 and 2013. Both tests of association between variables were applied, such as univariate and multivariate survival and disease-free time. Results They were the highest prevalence of male patients, right resections and conventional type, the mean age was 61 years. Postoperative complications occurred in 24.2% and perioperative and subsequent mortality was 5% and 62% respectively. The most common tumor type was Squamous Cell Carcinoma (56.6%), and cancer stage IIIA, mostly in T2 tumors, with an average of 34.6% N2 commitment. Received neoadjuvant 55.7% and 57.3% adjuvant. The following risk factors depending on the risk of recurrence and death were found: over 70 years of age, history of arrhythmia, right pneumonectomy, N2 disease, presence of distress during admission, myocardial infarction or need for mechanical ventilation, advanced cancer stages, and the use of adjuvant. Conclusions We believe that there are pre- and intraoperative factors that influence both perioperative evolution and the back; directly impacting the survival and disease-free time and they must be taken into account by the surgical medical team.
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Singh, Sekhon Harmanjatinder. "Comparative study of post pneumonectomy compensatory lung response in growing male and female rats." Thesis, University of British Columbia, 1987. http://hdl.handle.net/2429/28396.

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Male and female Sprague-Dawley rats matched for litter and body weight, were subjected to left pneumonectomy and sham operations at four weeks of age. Three weeks following surgery, rats were sacrificed, and somatic and lung growth, pressure-volume curves, biochemical, and morphometric parameters were measured. Females weighed 48% less than males at the end of the experiment. Somatic growth of neither sex was effected by pneumonectomy. Following pneumonectomy, lung weight and lung volume increased significantly and matched that of both lungs of the sham-operated group in both sexes. The absolute amount of DNA and protein content also increased but was significantly less than that of both lungs of shams. Since females weighed less, absolute lung weight, lung volume, DNA and protein content increased more in males but specific parameters (i. e. values/ 100 g body weight) increased significantly less compared to females. This occurred because specific lung weight and volume decreased with increasing body weight. Mean linear intercept and mean chord length of alveoli were increased. Alveolar surface area increased by 51% in males and 31% in females, and matched that of both lungs of shams in males but not in females. The total number of alveoli increased 15% and 18% in males and females respectively and was significantly less compared to both lungs of shams in both sexes. After pneumonectomy, the post-caval lobe increased in volume 70% and 73% in males and females respectively as compared to a 60% and 47% increase in total lung volume. The mean linear intercept and mean chord length of alveoli increased less in the upper and lower lobes compared to the middle and post-caval lobes in males as well as in females. The number of alveoli per unit volume decreased more in middle and post-caval lobes compared to the upper and lower lobes in both sexes. In sham-operated male rats the upper and lower lobes had a smaller mean linear intercept and mean chord length of alveoli compared to the post-caval lobe. Postpneumonectomy, loss of elastic lung recoil at mid-volumes was observed in females. It was inferred that compensatory response following pneumonectomy was in general similar in males and females. While there was an evidence of alveolar multiplication, simple dilation of airspaces occurred and this was the dominant effect especially in females. In certain aspects (weight, volume) compensatory growth was complete but in most (DNA. protein, morphometry) was not. Male and female differences could not account for differing results in the literature concerning completeness or otherwise of lung compensatory growth.
Medicine, Faculty of
Pathology and Laboratory Medicine, Department of
Graduate
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Tuohy, J. M. "An investigation into the compensatory hyperplastic response in larval and adult amphibia after unilateral pneumonectomy." Thesis, University of Portsmouth, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.374087.

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Books on the topic "Pneumonectomy"

1

Burch, Buford H. Atlas of pulmonary resections. 2nd ed. Springfield, Ill., U.S.A: Thomas, 1988.

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Srabani, Banerjee, and Canadian Coordinating Office for Health Technology Assessment., eds. Comparison of lung volume reduction surgery with medical management for emphysema. Ottawa: Canadian Coordinating Office for Health Technology Assessment, 2004.

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(Editor), Henry E. Fessler, Jr., John J. Reilly (Editor), and David Sugarbaker (Editor), eds. Lung Volume Reduction Surgery for Emphysema (Lung Biology in Health and Disease). Informa Healthcare, 2003.

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Lung volume reduction surgery for emphysema: Systematic review of studies comparing different procedures. Ottawa: Canadian Coordinating Office for Health Technology Assessment, 2005.

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Reilly, John, David Sugarbaker, and Henry Fessler. Lung Volume Reduction Surgery for Emphysema. University of Cambridge ESOL Examinations, 2002.

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Agarwal, Anil, Neil Borley, and Greg McLatchie. Cardiothoracic surgery. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199608911.003.0012.

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This chapter on cardiothoracic surgery describes cardiac operations such as coronary artery bypass grafting, aortic and mitral valve replacement, atrial septal defect repair, and cardiac transplantation. Steps of sternotomy, saphenous vein harvest, and cardiopulmonary bypass are included. Thoracic operations described are intercostal drain insertion, thoracotomy, lung biopsy, pulmonary lobectomy, pneumonectomy, thymectomy, bullectomy, and pleurectomy. Rigid and flexible bronchoscopy are also described.
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Clemente, Crisci, ed. Il Cancro del polmone: A 50 anni dalla prima pneumonectomia : atti del convegno internazionale, Firenze 25-26 novembre 1983 = Lung cancer : 50 years from the first pneumonectomy : proceedings international meeting, Florence 25th-26th november 1983. Firenze: AKOS, 1985.

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Todd, Claire, and Bruce McCormick. Thoracic surgery. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198719410.003.0015.

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This chapter discusses the anaesthetic management of thoracic surgery. It begins with general principles of thoracic surgery, including isolation of the lungs, one-lung ventilation, and providing analgesia for thoracic surgery. Surgical procedures covered include rigid bronchoscopy and bronchial stent insertion, mediastinoscopy, wedge resection, lobectomy, pneumonectomy, thoracoscopy and video-assisted thoracoscopic surgery, drainage of empyema and decortications, lung volume reduction surgery and bullectomy, repair of bronchopleural fistula, pleurectomy and pleurodesis, oesophagectomy, and surgical management of chest injuries.
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Argenziano, Michael, and Mark E. Ginsburg. Lung Volume Reduction Surgery. Humana, 2010.

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(Editor), Michael Argenziano, and Mark E. Ginsburg (Editor), eds. Lung Volume Reduction Surgery. Humana Press, 2002.

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Book chapters on the topic "Pneumonectomy"

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Chen, Ying Tai, Guanchao Jiang, Jun Wang, Fengwei Li, and Teng Mu. "Pneumonectomy." In Atlas of Minimally Invasive Surgery for Lung and Esophageal Cancer, 185–96. Dordrecht: Springer Netherlands, 2017. http://dx.doi.org/10.1007/978-94-024-0835-5_7.

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Ng, Ju-Mei. "Pneumonectomy." In Practical Handbook of Thoracic Anesthesia, 363–74. Boston, MA: Springer US, 2011. http://dx.doi.org/10.1007/978-0-387-88493-6_22.

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Wells, Francis C., and Aman S. Coonar. "Right Pneumonectomy." In Thoracic Surgical Techniques, 111–15. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-66270-1_27.

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Wells, Francis C., and Aman S. Coonar. "Left Pneumonectomy." In Thoracic Surgical Techniques, 121–23. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-66270-1_29.

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Dexter, Elisabeth U., and Todd L. Demmy. "Thoracotomy Pneumonectomy." In Chest Surgery, 137–46. Berlin, Heidelberg: Springer Berlin Heidelberg, 2014. http://dx.doi.org/10.1007/978-3-642-12044-2_14.

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Ng, Ju-Mei. "Extrapleural Pneumonectomy." In Principles and Practice of Anesthesia for Thoracic Surgery, 395–404. New York, NY: Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-0184-2_28.

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de la Torre, Mercedes, Eva Mª Fieira, and Marina Paradela. "Right Pneumonectomy." In Atlas of Uniportal Video Assisted Thoracic Surgery, 169–73. Singapore: Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-2604-2_27.

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Pouw, Matthew. "Post-pneumonectomy." In Essential Radiology Review, 91–93. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-26044-6_22.

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Ng, Ju-Mei. "Extrapleural Pneumonectomy." In Practical Handbook of Thoracic Anesthesia, 375–87. Boston, MA: Springer US, 2011. http://dx.doi.org/10.1007/978-0-387-88493-6_23.

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Ng, Ju-Mei. "Extrapleural Pneumonectomy." In Principles and Practice of Anesthesia for Thoracic Surgery, 587–96. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-00859-8_36.

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Conference papers on the topic "Pneumonectomy"

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Yu, D. K., F. J. Marquez, and R. Alalawi. "Bronchoscopic Pneumonectomy with Endobronchial Valves: A Minimally Invasive Alternative to Traditional Surgical Pneumonectomy." In American Thoracic Society 2022 International Conference, May 13-18, 2022 - San Francisco, CA. American Thoracic Society, 2022. http://dx.doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a4144.

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Kang, Min-Yeong, Hervé Guénard, and Bernard Sapoval. "Prediction of post-pneumonectomy respiration." In ERS International Congress 2016 abstracts. European Respiratory Society, 2016. http://dx.doi.org/10.1183/13993003.congress-2016.pa589.

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Khudaybergenov, Shukhrat, Otabek Eshonkhodjaev, Rustem Hayaliev, Sharif Rahimiy, and Dilyara Mazinova. "Bronchial stump insufficiency after pneumonectomy." In ERS International Congress 2020 abstracts. European Respiratory Society, 2020. http://dx.doi.org/10.1183/13993003.congress-2020.3126.

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Ferraris, Victor A., and Sibu P. Saha. "Pneumonectomy For Non-Malignant Disease." In American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California. American Thoracic Society, 2012. http://dx.doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a5838.

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Rhee, J. A. C., A. Voronina, C. Castaneda, O. A. Abe, and X. Dai. "Post Pneumonectomy Pulmonary Embolism: A Perplexing Problem." In American Thoracic Society 2020 International Conference, May 15-20, 2020 - Philadelphia, PA. American Thoracic Society, 2020. http://dx.doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a7269.

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Reed, Michael F., and Jennifer W. Toth. "Endobronchial Intervention Prior To Right Carinal Pneumonectomy." In American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California. American Thoracic Society, 2012. http://dx.doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a5197.

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Ceylan, Kenan Can, Güntuğ Batıhan, and Seyda Örs Kaya. "Endobronchial treatment for post-pneumonectomy bronchopleural fistula." In ERS International Congress 2021 abstracts. European Respiratory Society, 2021. http://dx.doi.org/10.1183/13993003.congress-2021.pa857.

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Jemsi, M., A. Martens, T. Stork, L. Fangmann, M. Zaatar, T. Plönes, S. Collaud, et al. "Prognostic factors after pneumonectomy in lung cancer." In 31. Jahrestagung der Deutschen Gesellschaft für Thoraxchirurgie. Georg Thieme Verlag, 2022. http://dx.doi.org/10.1055/s-0042-1754203.

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Zhu, R., and B. Lee. "Extrapleural Pneumonectomy for Advanced Thymoma with Pleural Metastasis." In American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX. American Thoracic Society, 2019. http://dx.doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a3930.

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Schecter, S., and B. K. Gehlbach. "Herniation and Empyema of the Post-Pneumonectomy Space." In American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX. American Thoracic Society, 2019. http://dx.doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a6402.

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