Relevant bibliographies by topics / PMOR

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  2. Dissertations / Theses
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  4. Book chapters
  5. Conference papers
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Academic literature on the topic 'PMOR'

Author: Grafiati
Published: 4 June 2021
Last updated: 20 February 2023

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Journal articles on the topic "PMOR"

1

Fiorani, Mara, and Augusto Accorsi. "Dietary flavonoids as intracellular substrates for an erythrocyte trans-plasma membrane oxidoreductase activity." British Journal of Nutrition 94, no. 3 (September 2005): 338–45. http://dx.doi.org/10.1079/bjn20051504.

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The plasma membrane oxidoreductase (PMOR) activity, which mainly utilises ascorbate as intracellular electron donor, represents a major mechanism for cell-dependent reduction of extracellular oxidants and might be an important process used by the erythrocytes to keep a reduced plasma environment. We previously reported that in human erythrocytes, myricetin and quercetin act as intracellular substrates of a PMOR showing a novel mechanism whereby these flavonoids could exert beneficial effects under oxidative stress conditions. Here, we evaluated the ability of different flavonoids (quercetin, myricetin, morin, kaempferol, fisetin, catechin, luteolin, apigenin, acacetin, rutin, taxifolin, naringenin, genistein) and of two in vivoO-methylated metabolites of quercetin (isorhamnetin and tamarixetin) to be substrates of PMOR, by comparing their antioxidant capacity (i.e. direct interaction with the oxidant ferricyanide or with the free radical 1,1-diphenyl-2-picryl-hydrazil) with their ability to penetrate the erythrocytes and donate electrons to the PMOR. The results obtained indicate that, although most of the flavonoids display significant antioxidant activities, only those (quercetin, myricetin, fisetin) that combine the cathecol structure of the B ring (responsible for the reducing activity) with the 2,3 double bond and 4-oxo function of the C ring (responsible for the uptake by erythrocytes) can act as intracellular substrates for PMOR. It is of note that the metabolites of quercetin enter erythrocytes and donate electrons to the PMOR as the parent compound. The present data show a relationship between the flavonoid structures and their ability to provide electrons to the PMOR, suggesting an additional mechanism whereby dietary flavonoids may exert beneficial effects in man.
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2

Valsamakis, Alexandra, Paul G. Auwaerter, Bert K. Rima, Hideto Kaneshima, and Diane E. Griffin. "Altered Virulence of Vaccine Strains of Measles Virus after Prolonged Replication in Human Tissue." Journal of Virology 73, no. 10 (October 1, 1999): 8791–97. http://dx.doi.org/10.1128/jvi.73.10.8791-8797.1999.

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ABSTRACT To understand the molecular determinants of measles virus (MV) virulence, we have used the SCID-hu thymus/liver xenograft model (SCID-hu thy/liv) in which in vivo MV virulence phenotypes are faithfully duplicated. Stromal epithelial and monocytic cells are infected by MV in thymus implants, and virulent strains induce massive thymocyte apoptosis, although thymocytes are not infected. To determine whether passage of an avirulent vaccine strain in human tissue increases virulence, we studied a virus isolated from thymic tissue 90 days after infection with the vaccine strain Moraten (pMor-1) and a virus isolated from an immunodeficient child with progressive vaccine-induced disease (Hu2). These viruses were compared to a minimally passaged wild-type Edmonston strain (Ed-wt) and the vaccine strain Moraten. pMor-1, Hu2, and Ed-wt displayed virulent phenotypes in thymic implants, with high levels of virus being detected by 3 days after infection (105.2, 102.8, and 103.4, respectively) and maximal levels being detected between 7 and 14 days after infection. In contrast, Moraten required over 14 days to grow to detectable levels. pMor-1 produced the highest levels of virus throughout infection, suggesting thymic adaptation of this strain. Similar to other virulent strains, Ed-wt, Hu2, and pMor-1 caused a decrease in the number of viable thymocytes as assessed by trypan blue exclusion and fluorescence-activated cell sorter analysis. Thymic architecture was also disrupted by these strains. Sequence analysis of the hemagglutinin (H) and matrix (M) genes showed no common changes in Hu2 and pMor-1. M sequences were identical in pMor-1 and Mor and varied in H at amino acid 469 (threonine to alanine), a position near the base of propeller 4 in the propeller blade/stem model of H structure. Further study will provide insights into the determinants of virulence.
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3

Bellam Muralidhar, Nanda Kishore, Natalie Rauter, Andrey Mikhaylenko, Rolf Lammering, and Dirk A. Lorenz. "Parametric Model Order Reduction of Guided Ultrasonic Wave Propagation in Fiber Metal Laminates with Damage." Modelling 2, no. 4 (November 3, 2021): 591–608. http://dx.doi.org/10.3390/modelling2040031.

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This paper focuses on parametric model order reduction (PMOR) of guided ultrasonic wave propagation and its interaction with damage in a fiber metal laminate (FML). Structural health monitoring in FML seeks to detect, localize and characterize the damage with high accuracy and minimal use of sensors. This can be achieved by the inverse problem analysis approach, which employs the signal measurement data recorded by the embedded sensors in the structure. The inverse analysis requires us to solve the forward simulation of the underlying system several thousand times. These simulations are often exorbitantly expensive and trigger the need for improving their computational efficiency. A PMOR approach hinged on the proper orthogonal decomposition method is presented in this paper. An adaptive parameter sampling technique is established with the aid of a surrogate model to efficiently update the reduced-order basis in a greedy fashion. A numerical experiment is conducted to illustrate the parametric training of the reduced-order model. The results show that the reduced-order solution based on the PMOR approach is accurately complying with that of the high fidelity solution.
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4

Roy, Ananya, M. Nabi, and Najmur Rahman. "Finite element compatible matrix interpolation for parametric model order reduction of electrothermal microgripper." Journal of Computational Design and Engineering 8, no. 6 (December 2021): 1622–35. http://dx.doi.org/10.1093/jcde/qwab066.

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Abstract Electrothermal microgrippers are nowadays commonly used as they are small in size, low cost, and easy to manufacture. The microgripper is modeled through partial differential equations, which are discretized by the finite element method (FEM), producing a large number of ordinary differential equations. This makes model order reduction (MOR) a fruitful proposition. Moreover, in design applications, the microgripper needs to be simulated repeatedly, with varying values of certain parameters. When these parameters are geometric in nature, matrix interpolation-based parametric model order reduction (pMOR) is the most suited method. However, in finite element applications, the sizes of the FE matrices change for varying geometrical parameters. The conventional matrix interpolation-based pMOR method becomes inapplicable for such cases, which remains a major drawback of this otherwise powerful algorithm. In this paper, this major hurdle is removed, and a new finite element compatible matrix interpolation (FEMI) for pMOR is proposed. A three-dimensional electrothermal microgripper is modeled parametrically using this proposed methodology. The effectiveness of the proposed method is shown through simulation results.
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5

Morre, D. M., G. Lenaz, and D. J. Morre. "Surface oxidase and oxidative stress propagation in aging." Journal of Experimental Biology 203, no. 10 (May 15, 2000): 1513–21. http://dx.doi.org/10.1242/jeb.203.10.1513.

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This report summarizes new evidence for a plasma-membrane-associated hydroquinone oxidase designated as CNOX (constitutive plasma membrane NADH oxidase) that functions as a terminal oxidase for a plasma membrane oxidoreductase (PMOR) electron transport chain to link the accumulation of lesions in mitochondrial DNA to cell-surface accumulations of reactive oxygen species. Previous considerations of plasma membrane redox changes during aging have lacked evidence for a specific terminal oxidase to catalyze a flow of electrons from cytosolic NADH to molecular oxygen (or to protein disulfides). Cells with functionally deficient mitochondria become characterized by an anaerobic metabolism. As a result, NADH accumulates from the glycolytic production of ATP. Elevated PMOR activity has been shown to be necessary to maintain the NAD(+)/NADH homeostasis essential for survival. Our findings demonstrate that the hyperactivity of the PMOR system results in an NADH oxidase (NOX) activity capable of generating reactive oxygen species at the cell surface. This would serve to propagate the aging cascade both to adjacent cells and to circulating blood components. The generation of superoxide by NOX forms associated with aging is inhibited by coenzyme Q and provides a rational basis for the anti-aging activity of circulating coenzyme Q.
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6

Setiawan, Fery, Arif Rahman Nurdianto, Rizal Fauzi Nurdianto, Heribertus Agustinus B. Tena, and Jenny Sunariani. "PERAN KAPSAISIN PADA PENGHAMBATAN TERJADINYA KANKER." MEDFARM: Jurnal Farmasi dan Kesehatan 10, no. 2 (December 30, 2021): 51–64. http://dx.doi.org/10.48191/medfarm.v10i2.62.

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Kapsaisin (8-methyl-N-vanillyl-6-nonanenamide) adalah rasa pedas utama dalam batang cabai yang dikonsumsi secara umum. Fungsi utama kapsaisin adalah mengurangi rasa nyeri dan inflamasi neurogenik, selain itu juga memiliki efek anti-tumor. Reseptor kapsaisin dan substansi lain yang terkait dengan kapsaisin telah diidentifikasi dan dikloningkan. Reseptor ini adalah reseptor vaniloid subtipe 1 (VR-1), yang membentuk saluran kation non-selektif dalam membran plasma yang memediasi beberapa efek pleitropik. Kapsaisin dan substansi analog yang sejenis mempunyai efek anti-proliferatif dalam sel kanker manusia melalui induksi siklus sel fase G0/G1 sehingga proliferasi sel terhenti dan terjadi apoptosis pada beberapa sel yang mengalami transformasi. Kemampuan untuk menginduksi apoptosis merupakan aktivitas supresi plasma membran NADH-oksidoreduktase (PMOR), enzim yang mentransfer elektron dari sitoplasmik NADH melalui ko-enzim Q (ubikuinon) ke akseptor elektron eksternal, seperti oksigen. Selain menginduksi apoptosis melalui PMOR, kapsaisin juga menginduksi peningkatan p21, Bax, dan Poly ADP Ribose Polymerase (PARP). Mekanisme antitumor kapsaisin secara utama dengan melakukan stabilisasi dan aktivasi gen p53. Kapsaisin secara substansial memperpanjang siklus hidup p53 dan secara signifikan meningkatkan aktivitas transkripsional p53. PMOR diperkirakan terlibat dalam pengaturan pertumbuhan sel dan proliferasi dengan menjaga rasio NADH+/NADH yang sesuai dengan kebutuhan sel.
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7

Yamaki, M., G. R. O. Menezes, A. L. C. Paiva, L. Barbosa, R. F. Silva, R. B. Teixeira, R. A. Torres, and P. S. Lopes. "Estudo de características de produção de matrizes de corte por meio da análise de componentes principais." Arquivo Brasileiro de Medicina Veterinária e Zootecnia 61, no. 1 (February 2009): 227–31. http://dx.doi.org/10.1590/s0102-09352009000100032.

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Avaliou-se o descarte de variáveis de produção, em análises de componentes principais, de três linhagens de matrizes de corte do Programa de Melhoramento Genético da Universidade Federal de Viçosa, utilizando informações de 270 aves, sendo 90 de cada linhagem. As características analisadas foram dias para postura do primeiro ovo (DPPO), taxa de postura da 22ª a 56ª semana (TP), peso médio individual na 32ª (PMI1), na 40ª (PMI2), na 48ª (PMI3), na 56ª (PMI4) e na 64ª semana (PMI5) e peso médio do ovo, obtido pela média da pesagem de três ovos na 32ª (PMO1), na 40ª (PMO2), na 48ª (PMO3), na 56ª (PMO4) e na 64ª semana (PMO5). Dos 12 componentes principais, sete apresentaram variância menor do que 0,7 (autovalor menor do que 0,7), sugerindo-se sete variáveis para descarte. As variáveis descartadas foram aquelas que apresentaram maiores coeficientes, em valor absoluto, a partir do último componente principal. Observou-se correlação linear simples e significativa entre as variáveis descartadas e as não descartadas, que indica redundância de variáveis, razão do descarte. Recomendam-se as variáveis: DPPO, TP, PM14, PMO1 e PMO4 para o estudo de características da produção de matrizes de frango de corte por meio da análise de componentes principais.
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8

Kormann, A. C. M., K. F. Portella, P. N. Pereira, and R. P. Santos. "Study of the performance of four repairing material systems for hydraulic structures of concrete dams." Cerâmica 49, no. 309 (March 2003): 48–54. http://dx.doi.org/10.1590/s0366-69132003000100011.

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Four types of repairing materials are studied as function of either a conventional concrete or a reference-concrete (RefC), these are: polymer-modified cement mortar (PMor), steel fiber concrete (SFco), epoxy mortar (EMor) and silica fume mortar (SFmo), to be applied in hydraulic structures surfaces subjected to a high velocity water flow. Besides the mechanical requests and wearing resistance of hydraulic concrete dam structures, especially the spillway surfaces, the high solar radiation, the environmental temperature and wet and dry cycles, contribute significantly to the reduction of their lifespan. RefC and the SFco were developed based on a usual concrete mixture used in slabs of spillways. The average RefC mixture used was 1: 1.61: 2.99: 0.376, with Pozzolan-modified Portland cement consumption of 425 kg/m³. EMor and PMor mixtures followed the information given by the manufacturers and lab experience. Tests on concrete samples were carried out in laboratory simulating normally found environmental situations in order to control the mechanical resistance and the aging imposed conditions, such as solar radiation and humidity. Also, physicochemical characterizing tests were made for all used materials. From the analyzed results, two of them presented a higher performance: the EMor and SFmo. SFco presented good adherence to the RefC and good mechanical performance. However, it also presented apparent metal corrosion in humidity tests, being indicated for use, with caution, as an intermediate layer in underwater repairs. In a general classification, considering all tests, including their field applications, the better performance material systems were EMor- SFmo> SFco> PMor.
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9

Okita, Noriko, Toshihiro Hoaki, Shinya Suzuki, and Masashi Hatamoto. "Characteristics of aerobic methane-oxidising bacterial community at the sea-floor surface of the Nankai Trough." Marine and Freshwater Research 71, no. 10 (2020): 1252. http://dx.doi.org/10.1071/mf19317.

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Methane hydrate is one of the new energy sources, but methane leakage could cause environmental issues such as marine ecosystem changes and global warming. The methane-oxidising bacterial (MOB) community could reflect the methane concentration, thus it may be an indicator of methane leakage. We obtained two sea-floor surface samples from a methane seep area and 12 samples from other general sea-floor areas of the Nankai Trough for the detection and phylogenetic analysis of the particulate methane monooxygenase (pmoA) gene. Using quantitative polymerase chain reaction analysis, the methane seep samples were found to have 106 copies of the pmoA gene per gram of sediment, whereas the general sea-floor area samples of the Nankai Trough contained 103–104 copies of the gene per gram of sediment. Phylogenetic analysis of the pmoA gene sequences showed that the sequences detected in the general and methane seep area samples differed significantly. Specifically, the pmof1–pmor primer pair could detect pmoA genes for the methane seep area, whereas pmoA gene from the general seafloor samples could be detected only using the A189–mb661 primer pair. The results of this study may facilitate the detection of unintended leakage of methane at methane hydrate production sites by monitoring MOB communities using pmoA-targeted phylogenetic analysis and quantification.
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10

Yamaki, Marcos, Gilberto Romeiro de Oliveira Menezes, Rafael Bastos Teixeira, Leandro Barbosa, André Luis da Costa Paiva, and Robledo de Almeida Torres. "Divergência genética entre linhagens de matrizes de corte por meio de análise de agrupamento." Revista Brasileira de Zootecnia 37, no. 5 (May 2008): 829–33. http://dx.doi.org/10.1590/s1516-35982008000500008.

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Este trabalho foi realizado com o objetivo de avaliar a divergência genética de três linhagens de matrizes de corte do Programa de Melhoramento Genético da UFV. Foram avaliados dados de 270 aves, 90 de cada linhagem, para estudo das características dias para o primeiro ovo (DPPO), taxa de postura da 22ª à 56ª semana (TP), peso médio individual na 32ª (PMI1), 40ª (PMI2), 48ª (PMI3), 56ª (PMI4) e 64ª semanas de idade (PMI5); e peso médio do ovo, obtido pela média da pesagem de três ovos na 32ª (PMO1), 40ª (PMO2), 48ª (PMO3), 56ª (PMO4) e 64ª semanas de idade (PMO5). Para avaliar a divergência, foram utilizados dois métodos: hierárquico do vizinho mais próximo e otimização de Tocher. Pelo método hierárquico do vizinho mais próximo, utilizando-se a distância de Mahalanobis ao quadrado (D²) como medida de dissimilaridade, formou-se um único grupo. Pelo método de otimização de Tocher, foram formados dois grupos, comprovando que os dois métodos foram discordantes na avaliação da divergência genética de linhas de aves de corte. As características que apresentaram as contribuições relativas mais expressivas para a divergência foram, respectivamente, PMO1 (25,71%), DDPO (21,76%), PMI4 (17,65%) e PMI2 (13,04%).
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Dissertations / Theses on the topic "PMOR"

1

Kennett, Eleanor. "Transmembrane Electron Transport Systems in Erythrocyte Plasma Membranes." University of Sydney. School of Molecular and Microbial Biosciences, 2005. http://hdl.handle.net/2123/620.

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Electron transport systems exist in the plasma membranes of all cells. Although not well characterised they play roles in cell growth and proliferation, hormone responses and other cell signalling events, but perhaps their most important role, especially in erythrocytes, is enabling the cell to respond to changes in both intra- and extracellular redox environments. Human erythrocytes possess a transmembrane electron transport capability that mediates the transfer of reducing equivalents from reduced intracellular species to oxidised extracellular species and is concomitant with proton extrusion. In the work for this thesis I showed that erythrocyte membranes contain a transmembrane WST-1 (water soluble tetrazolium-1) reductase activity that uses reducing equivalents from intracellular NADH to reduce extracellular WST-1. The rate of WST-1 reduction was increased by the presence of phenazine methosulfate and, although of low activity, it showed similar properties to a previously reported transmembrane NADH-oxidase activity. 1H NMR experiments showed that WST-1 was reversibly bound to the membrane and/or proteins in the membrane within the timeframe of the NMR experiment, confirming the location of the WST-1 reduction. Preliminary attempts to purify NADH:WST-1 reductase and NADH:ferricyanide reductase activities from the erythrocyte plasma membrane were inconclusive. The protein(s) responsible for the reduction of these oxidants appear to be of low abundance in the plasma membrane and may be part of a larger protein complex. Further work on the isolation of these redox activities is required before the protein(s) involved can be identified with any confidence. The ability of cells to export electrons suggests that an electron import mechanism might also exist to re-establish the cell�s redox-buffering equilibrium under conditions of oxidative stress. This hypothesis was tested in glucose-deprived erythrocytes using reduced glutathione and NADH as extracellular electron donors. It was shown that neither reduced glutathione nor NADH donated reducing equivalents through a transmembrane redox system. Extracellular NADH was, however, able to produce profound changes in starvation metabolism and methaemoglobin reduction rates. The addition of extracellular NADH caused a six-fold increase in the rate of lactate production above that observed in glucose-starved controls, together with a concomitant decrease in pyruvate production. In erythrocytes containing high levels of methaemoglobin, extracellular NADH increased the rate of methaemoglobin reduction in both the presence and absence of glucose. These results were explained by the leakage of lactate dehydrogenase from erythrocytes due to an admittedly low level of haemolysis. This caused the displacement of the intracellular pseudo-equilibrium of the lactate dehydrogenase reaction via transmembrane exchange of lactate, allowing the conversion of extracellular pyruvate to lactate and resulted in an increase in intracellular NADH concentrations. The latter increased the rate of methaemoglobin reduction. In conclusion, the work described in this thesis showed that erythrocyte membranes do not contain mechanisms for importing electrons or reducing equivalents from extracellular reduced glutathione or NADH. Erythrocytes do, however, contain an electron export system which can reduce extracellular oxidants such as WST-1 and the activity of this system depends on an intricate balance between intracellular antioxidants and enzyme activities. There is much still to be learnt about plasma membrane redox systems, little is known, for example, about the protein composition, mechanism of action, and the in vivo conditions under which these systems are most active.
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2

Kennett, Eleanor. "Transmembrane Electron Transport Systems in Erythrocyte Plasma Membranes." Thesis, The University of Sydney, 2004. http://hdl.handle.net/2123/620.

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Electron transport systems exist in the plasma membranes of all cells. Although not well characterised they play roles in cell growth and proliferation, hormone responses and other cell signalling events, but perhaps their most important role, especially in erythrocytes, is enabling the cell to respond to changes in both intra- and extracellular redox environments. Human erythrocytes possess a transmembrane electron transport capability that mediates the transfer of reducing equivalents from reduced intracellular species to oxidised extracellular species and is concomitant with proton extrusion. In the work for this thesis I showed that erythrocyte membranes contain a transmembrane WST-1 (water soluble tetrazolium-1) reductase activity that uses reducing equivalents from intracellular NADH to reduce extracellular WST-1. The rate of WST-1 reduction was increased by the presence of phenazine methosulfate and, although of low activity, it showed similar properties to a previously reported transmembrane NADH-oxidase activity. 1H NMR experiments showed that WST-1 was reversibly bound to the membrane and/or proteins in the membrane within the timeframe of the NMR experiment, confirming the location of the WST-1 reduction. Preliminary attempts to purify NADH:WST-1 reductase and NADH:ferricyanide reductase activities from the erythrocyte plasma membrane were inconclusive. The protein(s) responsible for the reduction of these oxidants appear to be of low abundance in the plasma membrane and may be part of a larger protein complex. Further work on the isolation of these redox activities is required before the protein(s) involved can be identified with any confidence. The ability of cells to export electrons suggests that an electron import mechanism might also exist to re-establish the cell's redox-buffering equilibrium under conditions of oxidative stress. This hypothesis was tested in glucose-deprived erythrocytes using reduced glutathione and NADH as extracellular electron donors. It was shown that neither reduced glutathione nor NADH donated reducing equivalents through a transmembrane redox system. Extracellular NADH was, however, able to produce profound changes in starvation metabolism and methaemoglobin reduction rates. The addition of extracellular NADH caused a six-fold increase in the rate of lactate production above that observed in glucose-starved controls, together with a concomitant decrease in pyruvate production. In erythrocytes containing high levels of methaemoglobin, extracellular NADH increased the rate of methaemoglobin reduction in both the presence and absence of glucose. These results were explained by the leakage of lactate dehydrogenase from erythrocytes due to an admittedly low level of haemolysis. This caused the displacement of the intracellular pseudo-equilibrium of the lactate dehydrogenase reaction via transmembrane exchange of lactate, allowing the conversion of extracellular pyruvate to lactate and resulted in an increase in intracellular NADH concentrations. The latter increased the rate of methaemoglobin reduction. In conclusion, the work described in this thesis showed that erythrocyte membranes do not contain mechanisms for importing electrons or reducing equivalents from extracellular reduced glutathione or NADH. Erythrocytes do, however, contain an electron export system which can reduce extracellular oxidants such as WST-1 and the activity of this system depends on an intricate balance between intracellular antioxidants and enzyme activities. There is much still to be learnt about plasma membrane redox systems, little is known, for example, about the protein composition, mechanism of action, and the in vivo conditions under which these systems are most active.
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3

Marek, Mary J. "PMOS CCD /." Online version of thesis, 1989. http://hdl.handle.net/1850/10563.

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4

AVRILLON, SYLVIE, and D. PERRET-GALLIX. "Un detecteur a pixels pmos." Chambéry, 1996. http://www.theses.fr/1996CHAMS018.

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Cette these presente un composant a pixel d'un type nouveau, qui pourra etre utilise pour la construction de detecteurs de trajectoires a grande resolution, pour les experiences de physique des particules. Ce pixel pmos a ete etudie dans le cadre de la recherche et developpement de l'experience belle a kek. Le pixel pmos, situe sur la face ohmique d'une diode pin desertee, se compose d'un puits-n ou un transistor pmos double drains est implante. Les sorties aux bornes des drains des pixels pmos du reseau, sont reliees entre elles par des strips de lecture. Ce pixel pmos a des caracteristiques interessantes: une amplification interne qui permet de detecter des particules chargees avec un signal-sur-bruit important, et l'avantage d'une lecture bi-dimensionnelle de type strip pour un composant simple face. Nous avons concu et fabrique des prototypes simplifies du pixel pmos, de differents types. A l'aide d'un faisceau infrarouge, nous avons verifie le principe de fonctionnement d'un pixel compose d'un transistor pmos double drains implante dans l'electrode d'une diode pin, ainsi que la lecture bi-dimensionnelle de type strip. L'amplification et les performances de bruit du pixel pmos ont ete estimees. Un test sur faisceau de particules au minium d'ionisation nous a permis de mesurer la distribution du depot d'energie et la resolution de position, en accord avec les simulations effectuees
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5

Fernandes, Thiago Henriques. "Divergência entre prática e recomendações para modelos de atuação do PMO: o caso de uma empresa de grande porte do setor industrial." reponame:Repositório Institucional do FGV, 2016. http://hdl.handle.net/10438/16548.

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The objective of this work was to identify what are the main divergences found between what the theory preconizes as scope and approach of the Project Management Offices (PMOs) and what really happens when practice is observed on site. Such intend was achieved with the support of a case study analysis. The theme may be considered relevant based on the fact that it provides a better comprehension about how the PMOs structures really operate. Specially regarding to scope, that is, whether the PMO is a Program-Project, a Departmental PMO, or a Corporate PMO, and regarding its range, that is, if its action is operational, tactical or strategic. Qualitative methodology was used in this research, through a case study approach. A large size manufacturing company not structured by projects was chosen to be evaluated. This company has a complex organizational structure and such characteristic makes possible a comprehensive study. The performance of the PMOs addressed in the case study was discussed taking in consideration the literature and also the information collected from the participant observation. The results of this work allows to conclude that the assumption of the research, that there are divergences between what the theory preconizes as scope and approach of the PMOs and what really happens on practice, is confirmed through the case study. Beyond that, there is not a clear causality relation between the amplitude of action of those PMOs and its hierarchic position within the organization. Also there is not a pattern of action of the PMOs when compared to functions that they perform. Finally, recommendations were made related to the case study presented. The main ones are shown as follows. It is important to hold a multi case study for a better comprehension of the theme with at least one company structured by projects and other one non-structured by projects in order to compare the performance of their PMOs aiming to better understand the theme. To include more stakeholders among the group of the interviewed people within the case study. To hold a survey with various companies of various segments inside the national territory. Also to perform a study where it may be verified whether different organizational typologies may affect the practice of PMOs in the organizations.
Neste trabalho, o objetivo é identificar, a partir da análise de um estudo de caso, quais são as principais divergências encontradas quando se compara o que a teoria preconiza como o escopo e a abordagem dos Project Management Offices - PMOs e o que acontece na prática, no que diz respeito à real atuação destas estruturas. O tema pode ser considerado relevante devido ao fato de fornecer uma melhor compreensão sobre como as estruturas de PMO realmente atuam, principalmente no que diz respeito ao escopo, isto é, se o PMO é um Programa-Projeto, um PMO Departamental ou um PMO Corporativo e relativamente a sua amplitude, ou seja, se sua atuação é operacional, tática ou estratégica. Para este estudo foi utilizada a metodologia qualitativa, por meio da abordagem de estudo de caso. Foi selecionada uma empresa de grande porte do setor de manufatura não estruturada por projeto para avaliação. A empresa do estudo de caso possui uma estrutura organizacional complexa que possibilita um estudo abrangente. A atuação dos PMOs do estudo de caso foi discutida à luz da revisão de literatura e levando-se em conta, também, as informações colhidas a partir da observação participante. Os resultados deste trabalho permitem concluir que o pressuposto defendido, que é a existência de divergências entre o que a teoria preconiza como escopo e abordagem do PMO e a real atuação dos PMOs, foi confirmado através do estudo de caso; além disso, não existe relação de causalidade clara entre o escopo de atuação dos PMOs e sua posição hierárquica dentro da empresa; e não existe uma atuação padrão destas estruturas, quando comparadas às funções que elas exercem. Por fim, são apresentadas recomendações relativas ao estudo de caso realizado, ou seja, é importante realizar um estudo multicasos entre ao menos uma empresa não estruturada por projeto e outra estruturada por projeto e comparar a atuação dos seus PMOs para melhor compreensão do tema, incluir mais stakeholders no grupo de entrevistados dentro do estudo de caso, realizar um survey com várias empresas de vários segmentos dentro do território nacional e um possível estudo onde seja verificado se tipologias diferentes de estruturas organizacionais podem afetar a atuação práticas dos PMOs.
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Fabián, Martin. "Opakovač pro PMR pásmo." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2010. http://www.nusl.cz/ntk/nusl-218749.

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The main target of this work is to project and make a simple repeater working in 446 MHz tape called PMR. This repeater is made from functional station PMR and repeating program unit, which was constructed by the help of the system for recording and replaying sound. The repeater is managed by microcontroller Atmel from line AVR. The repeater records minimal and maximal temperature during its operation and its date and time is still actual thanks to transceiver DCF. It is possible to connect the transceiver with a computer by the serial link.
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Hart, Sean Michael. "Intelligent Processing of PMR-15." W&M ScholarWorks, 1992. https://scholarworks.wm.edu/etd/1539625733.

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Wheeler, Arthur. "Comparison of fluoride release protocols for RMGIC/PMCR adhesives." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape4/PQDD_0018/MQ58099.pdf.

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Isheden, Christian. "Source and drain engineering in SiGe-based pMOS transistors." Doctoral thesis, Stockholm, 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-96.

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Lowrance, Sheri. "PMO lite for not-for-profit organization." [Denver, Colo.] : Regis University, 2009. http://adr.coalliance.org/codr/fez/view/codr:147.

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Books on the topic "PMOR"

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PMO diary. Delhi: Konark Publishers, 2003.

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1957-, Müller Ralf, and Glückler Johannes, eds. Governance and communities of PMOs. Newtown Square, Pa: Project Management Institute, 2012.

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Aubry, Monique. Governance and communities of PMOs. Newtown Square, Pa: Project Management Institute, 2012.

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Foorman, Barbara R. Progress monitoring for beginning readers (PMBR) teacher's guide. Baltimore, Md: Paul H. Brookes Pub. Co., 2006.

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Identifying the forces driving frequent change in PMOs. Newtown Square, Pa: Project Management Institute, Inc., 2011.

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Mahapatra, Souvik, ed. Recent Advances in PMOS Negative Bias Temperature Instability. Singapore: Springer Singapore, 2022. http://dx.doi.org/10.1007/978-981-16-6120-4.

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Thavamani, R. Preston PMR Ujian Topik Bahasa Inggeris. Petaling Jaya: Persekutuan Preston, 1994.

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Point, Act. International Project Management Standard. Guida All'acquisizione Delle Credenziali Pmpr e Capmr Del Pmir. Lulu Press, Inc., 2013.

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Kaplan PMBR FINALS: MPT (Kaplan Pmbr Finals). Kaplan Publishing, 2008.

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Kaplan PMBR Finals: Contracts (Kaplan Pmbr Finals). Kaplan Publishing, 2007.

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Book chapters on the topic "PMOR"

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Palacio-Castañeda, Valentina, Roland Brock, and Wouter P. R. Verdurmen. "Generation of Protein-Phosphorodiamidate Morpholino Oligomer Conjugates for Efficient Cellular Delivery via Anthrax Protective Antigen." In Methods in Molecular Biology, 129–41. New York, NY: Springer US, 2022. http://dx.doi.org/10.1007/978-1-0716-2010-6_8.

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AbstractPhosphorodiamidate morpholino oligomers (PMOs) offer great promise as therapeutic agents for translation blocking or splice modulation due to their high stability and affinity for target sequences. However, in spite of their neutral charge as compared to natural oligonucleotides or phosphorothioate analogs, they still show little permeability for cellular membranes, highlighting the need for effective cytosolic delivery strategies. In addition, the implementation of strategies for efficient cellular targeting is highly desirable to minimize side effects and maximize the drug dose at its site of action. Anthrax toxin is a three-protein toxin of which the pore-forming protein anthrax protective antigen (PA) can be redirected to a receptor of choice and lethal factor (LF), one of the two substrate proteins, can be coupled to various cargoes for efficient cytosolic cargo delivery. In this protocol, we describe the steps to produce the proteins and protein conjugates required for cytosolic delivery of PMOs through the cation-selective pore generated by anthrax protective antigen. The method relies on the introduction of a unique cysteine at the C-terminal end of a truncated LF (aa 1–254), high-yield expression of the (truncated) toxin proteins in E. coli, functionalization of a PMO with a maleimide group and coupling of the maleimide-functionalized PMO to the unique cysteine on LF by maleimide-thiol conjugation chemistry. Through co-administration of PA with LF-PMO conjugates, an efficient cytosolic delivery of PMOs can be obtained.
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Goossens, Remko, and Annemieke Aartsma-Rus. "In Vitro Delivery of PMOs in Myoblasts by Electroporation." In Methods in Molecular Biology, 191–205. New York, NY: Springer US, 2022. http://dx.doi.org/10.1007/978-1-0716-2010-6_12.

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AbstractAntisense oligonucleotides (AONs) are small synthetic molecules of therapeutic interest for a variety of human disease. Their ability to bind mRNA and affect its splicing gives AONs potential use for exon skipping therapies aimed at restoring the dystrophin transcript reading frame for Duchenne muscular dystrophy (DMD) patients. The neutrally charged phosphorodiamidate morpholino oligomers (PMOs) are a stable and relatively nontoxic AON modification. To assess exon skipping efficiency in vitro, it is important to deliver them to target cells. Here, we describe a method for the delivery of PMOs to myoblasts by electroporation. The described protocol for the Amaxa 4D X unit nucleofector system allows efficient processing of 16 samples in one nucleocuvette strip, aiding in high-throughput PMO efficacy screens.
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Siu, Christopher. "PMOS and CMOS." In Electronic Devices, Circuits, and Applications, 121–37. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-80538-8_7.

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Ha, Chang-Sik, and Sung Soo Park. "PMOs for Adsorption." In Periodic Mesoporous Organosilicas, 219–66. Singapore: Springer Singapore, 2018. http://dx.doi.org/10.1007/978-981-13-2959-3_7.

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Ha, Chang-Sik, and Sung Soo Park. "PMOs for Separation." In Periodic Mesoporous Organosilicas, 267–74. Singapore: Springer Singapore, 2018. http://dx.doi.org/10.1007/978-981-13-2959-3_8.

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Ha, Chang-Sik, and Sung Soo Park. "PMOs for Catalytic Applications." In Periodic Mesoporous Organosilicas, 125–87. Singapore: Springer Singapore, 2018. http://dx.doi.org/10.1007/978-981-13-2959-3_5.

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Barry, Maurice. "Polymyalgia Rheumatica (PMR)." In Clinical Practice in Rheumatology, 93–94. London: Springer London, 2003. http://dx.doi.org/10.1007/978-0-85729-430-2_18.

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Ortner, Gerhard, and Betina Stur. "Einteilungsmöglichkeiten für PMO." In Das Projektmanagement-Office, 19–31. Berlin, Heidelberg: Springer Berlin Heidelberg, 2019. http://dx.doi.org/10.1007/978-3-662-59486-5_3.

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Ortner, Gerhard, and Betina Stur. "Einteilungsmöglichkeiten für PMO." In Das Projektmanagement-Office, 21–33. Berlin, Heidelberg: Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-662-45277-6_3.

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Ortner, Gerhard, and Betina Stur. "Einteilungsmöglichkeiten für PMO." In Das Projektmanagement-Office, 21–30. Berlin, Heidelberg: Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-20786-0_3.

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Conference papers on the topic "PMOR"

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Roy, Ananya, and M. Nabi. "Efficient Simulation of Electro-Thermal Microgripper using PMOR." In 2018 Indian Control Conference (ICC). IEEE, 2018. http://dx.doi.org/10.1109/indiancc.2018.8307978.

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Bazaz, M. A., S. A. Nahve, M. Nabi, S. Janardhanan, and M. U. Rehman. "Adaptive parameter space sampling in matrix interpolatory pMOR." In 2015 International Conference on Recent Developments in Control, Automation and Power Engineering (RDCAPE). IEEE, 2015. http://dx.doi.org/10.1109/rdcape.2015.7281374.

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Smets, Gerrit, Erik Rosseel, Gunther Sterckx, Janusz Bogdanowicz, Wilfried Vandervorst, Derrick Shaughnessy, Jiro Matsuo, Masataka Kase, Takaaki Aoki, and Toshio Seki. "Transfer From Rs-based To PMOR-based Ion Implantation Process Monitoring." In ION IMPLANTATION TECHNOLOGY 2101: 18th International Conference on Ion Implantation Technology IIT 2010. AIP, 2011. http://dx.doi.org/10.1063/1.3548441.

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Alnuaimi, Aiysha, and Robert Joslin. "ANALYSING THE IMPACT OF PMO CULTURE ON PMO SUCCESS." In 10th IPMA Research conference: Value co-creation in the project society. International Project Management Association, Serbian Project Management Association, 2022. http://dx.doi.org/10.56889/azye5590.

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This study looks at the relationship between PMO culture and PMO success from a control theory perspective. PMO success was operationalized using three concepts: (a) domain of control, (b) domain of influence and (c) domain of concern. The motivation of the study is to understand if and how culture types could influence PMO success and what are the attributes of these cultures. Using Cameron and Quinn’s culture model, a cross-sectional, worldwide online survey yielded 219 responses. Analysis was done through factor analysis and moderated hierarchical regression analysis. The factor analysis showed that both clan and market culture types correlate to PMO success. A case study then determined the antecedents of culture types and how they influenced PMO success. PMOs that were more commercially focused, that is, supporting revenue-generating projects, were more market culture oriented, whereas PMOs that were internally focused were clan culture type. The implications for practitioners are that competence profiles of PMO people will need to be aligned to the culture type of the PMO that is linked to PMO success. The results are important for academics as PMOs have different culture types depending on the customers and the clients they serve.
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Zhang, Yi, Yan Luo, Jian-Qiang Hu, Tao Zhang, and Yun-Yun Xu. "Study on Antioxidation Properties of the Complex of Dithiocarbamate With Tolutriazole Antioxidant." In ASME/STLE 2007 International Joint Tribology Conference. ASMEDC, 2007. http://dx.doi.org/10.1115/ijtc2007-44020.

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The antioxidation properties of methylene bis(di-n-butyldithiocarbamate) (V 7723) - and tolutriazole derivative (V 887) - containing poly-a-olefin (PAO)-derived lubricants were evaluated by differential scanning calorimetry (DSC) and modified penn state micro-oxidation test (PMOT). DSC test measures incipient oxidation temperature (OT) and oxidation induction time (IT) of the lubricant at high temperatures and the oxidation stability of oil weight loss is measured by PMOT test. DSC test shows that OT and IT of V 7723-containing PAO were improved significantly by V 887 addition. PMOT test indicates that when combining with V 7723 antioxidants, V 887 can also effectively reduce the increase in weight loss of PAO. In addition, FTIR results from PMOT test confirm that addition of V 887 can significantly enhance the oxidation induction time of oils. These results suggest that the V 7723 shows a good oxidative synergism with V 887 antioxidant.
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Yeh, Shu-jen, and Henry Stark. "Learning in neural nets using projection methods." In OSA Annual Meeting. Washington, D.C.: Optica Publishing Group, 1990. http://dx.doi.org/10.1364/oam.1990.mn5.

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The method of generalized projections is applied to the multilayer feed-forward neural-net problem to derive a new learning algorithm.1 Unfortunately, strict adherence to the learning rule requires the solution of coupled, nonlinear algebraic equations. By permitting a simplification, a new learning rule results, which produces an implementable algorithm. We call this learning rule the projection-method learning rule (PMLR). We apply the PMLR to two well-known pattern-recognition problems, neither of which is solvable by a linear-discriminant scheme. The PMLR is compared with the error-back-propagation learning rule (BPLR) and is shown to converge faster than the BPLR for the problems being considered.
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Hu, Jian-Qiang, Xian-Jun Zeng, Wei Zhang, and Ben-Ke Shang. "The Synergistic Antioxidation Effects of Molybdenum Dialkydithiocarbamate With Arylamine Antioxidants." In STLE/ASME 2008 International Joint Tribology Conference. ASMEDC, 2008. http://dx.doi.org/10.1115/ijtc2008-71033.

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The antioxidation properties of molybdenum dialkyldithiocarbamate (M 807)- and p, p-dioctyldiphenylalmine (V 81)- or mixed octylated and butylated diphenylalmines (V 961)-containing poly-α-olefin (PAO)-derived lubricants were evaluated by differential scanning calorimetry (DSC) and modified penn state micro-oxidation test (PMOT). DSC test measures incipient oxidation temperature (OT) and oxidation induction time (IT) of the lubricant at high temperatures and the oxidation stability of oil weight loss is measured by PMOT test. DSC test shows that OT and IT of V 81-or V 961-containing PAO were improved significantly by M 807 addition. PMOT test indicates that when combining with V 81 antioxidants, M 807 can also effectively reduce the increase in weight loss of PAO and deposits formed in oils. These results suggest that the M 807 shows a good antioxidative synergism with alkylated diphenylamine antioxidants. In addition, FTIR results from PMOT test confirm that addition of M 807 can significantly enhance the oxidation induction time of oils containing V 81 and inhibit formation of oxidation products including carbonyl bonds or hydroxyl group.
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Hatakeyama, T., K. Fushinobu, and K. Okazaki. "Investigation of Device Interactions Between Two MOSFETs in Si CMOS." In ASME 2008 International Mechanical Engineering Congress and Exposition. ASMEDC, 2008. http://dx.doi.org/10.1115/imece2008-67204.

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Experimental works about the device interactions between nMOS and pMOS in bulk Si CMOS were performed. In the bulk Si CMOS, in the case that the distance between two MOSFETs is not enough, it is important to consider the risk of the device interactions between nMOS and pMOS. In this work, we fabricated bulk Si CMOS, in which the distance between pMOS and nMOS can be variable. And we observed the characteristics of the device operation by using fabricated CMOS under the dc bias condition. In this research, we focused on the leakage current between two MOSFETs in CMOS inverter depending on the distance between two MOSFETs, applied voltage and temperature. Experimental results showed that our fabricated CMOS shows quite small leakage current and the leakage current is less than 1% compared to CMOS on state current even with small distance between two MOSFETs at the high voltage condition and the high temperature condition.
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Peri, M. D. Murthy, James Kiely, Manuel C. Anaya-Dufresne, and Kent Bodurtha. "Study of Contact Detect Response for PMR and HAMR Media Using the Integrated Thermistor Based Proximity Sensor." In ASME 2020 29th Conference on Information Storage and Processing Systems. American Society of Mechanical Engineers, 2020. http://dx.doi.org/10.1115/isps2020-1958.

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Abstract As the Hard Disk Drive industry migrates from PMR to HAMR technology, it is important to understand differences in the measurement of contact detection between PMR vs. HAMR media. Compared to PMR media, HAMR media tends to be rougher and has a higher thermal conductance. Since some contact detection methods rely on interface heat transfer, it is important to understand the impact of media type on measurements. In the current paper, we present results from mechanical spinstand studies using the integrated thermistor in the head. The heater in the head is dithered at a fixed frequency and the thermistor response is analyzed at that frequency. Changes in the thermistor resistance as a function of head-media clearance are used to understand how thermal conduction differences between PMR vs. HAMR media may impact contact detection. We find that heat conduction is different between HAMR and PMR media types and can have an impact on contact detection.
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Stuart, M. J., J. Wu, C. Ganley, and S. Sunderji. "AMNIOTIC FLUID FROM TERM GESTATION ENHANCES PLATELET PRODUCTION OF VASOCONSTRICTOR THROMBOXANE: POTENTIAL ROLE IN PERSISTENT PULMONARY HYPERTENSION IN THE NEONATE." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644273.

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One of the causes of persistent pulmonary hypertension (PPH) in the neonate may involve the interaction of amniotic fluid (AF) and pits, with the release of thromboxane A2 (TXA2) causing an increase in pulmonary vascular tone. To prove or disprove this hypothesis, AF from term (n=6) and from 15 to 17 weeks gestation (n=6) were preincubated for 15 minutes with platelet rich plasma followed by the addition of thrombin or arachidonic acid, and plt. TXB2assessed by radioimmunoassay. AF from early gestation had no significant effect on the production of the potent pulmonary vasoconstrictor metabolite thromboxane. Mean plateletTXB2 formation in the presence of thrombin (0.2 unit per ml) was 0.5±0.26 (1SD) pmol per 106 pits, in control vs 0.65±0.4 pmol for paired prts preincubated with early gestation AF. However, plts.that had been preincubated with term AF prior to thrombin stimulation produced significantly greater amounts of TXB2 (0.79±0.4 pmol) compared to paired control aliquots (0.45±0.27; P<0.05). Similar results were observed using the pit. agonist arachidonic acid. The thromboxane enhancing capacity of term AF appeared to reside in its lipid fraction. When compared to a baseline production of 1.4±0.45 pmol TXB2 per 106 pits, in response to thrombin (1 unit per ml), unfractionated AF or its lipid fraction enhanced TXB2 production to 2.87±0.53 and 2.81±0.62 pmol respectively (P<0.01). Values for the aqueous extract however were no different from buffer control values (1.45±0.5). Following perinatal aspiration, and the absorption of AF into the pulmonary capillaries, in situ contact between AF and blood in the pulmonary vasculature could cause thrombin generation and the production of proaggregatory thromboxane. Recruitment of more pits and the production of the plt-fibrin thrombi that have been documented in the pulmonary microcirculation of neonates with perinatal aspiration and PPH could then occur. The use of thromboxane synthetase inhibitors in an experimental model of perinatal aspiration should be evaluated.
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Reports on the topic "PMOR"

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Tulp, I., T. C. Prins, J. A. M. Craeymeersch, S. IJff, and M. T. van der Sluis. Syntheserapport PMR NCV. IJmuiden: Wageningen Marine Research, 2018. http://dx.doi.org/10.18174/496768.

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Balzer, Robert, Howard Shrobe, Neil Goldman, and David Wile. Preventing Misuse of Operator Privilege (PMOP). Fort Belvoir, VA: Defense Technical Information Center, March 2006. http://dx.doi.org/10.21236/ada449252.

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Prins, Theo, Jaap van der Meer, Peter Herman, Ad van der Spek, Chun Chen, Eddy Wymenga, Els van der Zee, et al. Eindrapportage monitoring- en onderzoeksprogramma Natuurcompensatie Voordelta (PMR-NCV). Den Helder: Wageningen Marine Research, 2020. http://dx.doi.org/10.18174/524298.

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Crabtree, Donald J. Contract Pricing Handbook PMO Tactical Management Information Systems. Fort Belvoir, VA: Defense Technical Information Center, April 1985. http://dx.doi.org/10.21236/ada156174.

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Craeymeersch, J. A., K. J. Perdon, J. van Zwol, J. Jol, E. B. M. Brummelhuis, and M. van Asch. PMR Monitoring Natuurcompensatie Voordelta - bodemdieren : Veld- en datarapport campagnes met bodemschaaf in 2016, 2017 en 2018. Yerseke: Wageningen Marine Research, 2019. http://dx.doi.org/10.18174/496166.

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Alston, W. B., and R. W. Lauver. Effect of Substituted Phenylnadimides on Processing and Properties of PMR (Polymerization of Monomeric Reactants) Polyimide Composites. Fort Belvoir, VA: Defense Technical Information Center, January 1985. http://dx.doi.org/10.21236/ada150529.

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Xiang, Kemeng, Huiming Hou, and Ming Zhou. The efficacy of Cerus and Cucumis Polypeptide injection combined with Bisphosphonates on postmenopausal women with osteoporosis:A protocol for systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, May 2022. http://dx.doi.org/10.37766/inplasy2022.5.0067.

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Review question / Objective: The aim of this review is to evaluate the effectiveness of Cerus and Cucumis Polypeptide injection combined with Bisphosphonates for postmenopausal osteoporosis. Condition being studied: Postmenopausal osteoporosis (PMOP) is a disorder of bone metabolism caused by estrogen deficiency in women after menopause, which manifests clinically as pain, spinal deformities and even fragility fractures, affecting the quality of life of patients and possibly shortening their life span. Bisphosphonates are commonly used to control and delay the progression of the disease, improve the patient's symptoms and reduce the incidence of fragility fractures. However, single drugs are still lacking in controlling the progression of the disease, and the combination of drugs is the clinical priority.
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Koegler, Wendy S. One User's Report on Sandia Data Objects: Evaluation of the DOL and PMO for use in Future. Office of Scientific and Technical Information (OSTI), November 2003. http://dx.doi.org/10.2172/820203.

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Koegler, Wendy S., and W. Philip, Jr Kegelmeyer. One user's report on Sandia data objects : evaluation of the DOL and PMO for use in feature characterization. Office of Scientific and Technical Information (OSTI), November 2003. http://dx.doi.org/10.2172/918321.

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Rene, Schubert. Computing the Meridional Overturning Circulation from NEMO Output. GEOMAR, November 2021. http://dx.doi.org/10.3289/sw_3_2021.

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With this script, the Meridional Overturning Circulation (MOC) can be computed from NEMO ocean-model output for the whole globe or the Atlantic (AMOC), Indic (IMOC) and Pacific (PMOC) subbasins. The MOC is computable in z- and sigma coordinates. Moreover, for nested configurations, it is possible to combine data from both host and nest grids. Finally, it is possible to take into account of that the ORCA model grid is curvilinear north of 20°N: it is possible to compute the northward velocity component from the velocity field in x- and y- directions and to sum up the meridional flux over latitudional bands instead of in x-direction. When both steps are applied, the resulting MOC shows however strong variability in meridional direction. It needs to be clarified, whether this is realistic or not. The software is provided in the form of the jupyter notebook "MOC.ipynb" which includes more informations on the possibilites of the computations and an extensive appendix section with comparisons to computations with cdftools, as well as with details on the computation of the MOC including nest data and taking the curvilinearity of the grid into account. Necessary python modules are listed at the beginning of the document.
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